56423-63-3 | 2-Bromopyrazine

Packsize	Purity	Availability	Price	Discounted Price
250mg	95%	in stock	$8.00	$5.00
1g	95%	in stock	$8.00	$6.00
5g	95%	in stock	$24.00	$17.00
10g	95%	in stock	$42.00	$30.00
25g	95%	in stock	$98.00	$69.00

Description

• Catalog Number: AB43905
• Chemical Name: 2-Bromopyrazine
• CAS Number: 56423-63-3
• Molecular Formula: C4H3BrN2
• Molecular Weight: 158.984
• MDL Number: MFCD08275680
• SMILES: Brc1cnccn1

Computed Properties

• Complexity: 57.7
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 7
• Hydrogen Bond Acceptor Count: 2
• XLogP3: 0.9

Upstream Synthesis Route

2-Bromopyrazine is a versatile chemical compound commonly utilized in organic synthesis for a variety of important applications. As a brominated pyrazine derivative, it serves as a key building block for the construction of complex molecules in the pharmaceutical and agrochemical industries. Its unique structure and reactivity make it a valuable intermediate in the preparation of various biologically active compounds.In chemical synthesis, 2-Bromopyrazine is commonly employed as a precursor in the synthesis of heterocyclic compounds, such as pyrazoles and pyrazolines, which are essential scaffolds in medicinal chemistry. Its ability to undergo diverse chemical transformations, including cross-coupling reactions and nucleophilic substitutions, enables the efficient formation of novel, functionalized molecules with potential pharmacological activities.Moreover, 2-Bromopyrazine exhibits good compatibility with a range of reagents and reaction conditions, making it a reliable starting material for the synthesis of new drug candidates and agrochemicals. Its presence in the molecular structure of organic compounds often imparts desirable properties or biological activities, highlighting its significance in drug discovery and development processes.Overall, the strategic use of 2-Bromopyrazine in chemical synthesis plays a crucial role in the design and synthesis of biologically relevant molecules with potential applications in pharmaceuticals, agrochemicals, and materials science. Its versatility and synthetic utility make it a valuable tool for chemists seeking to access structurally diverse and functionally rich compounds for various research and industrial purposes.

Literature

• Aminopyrazine inhibitors binding to an unusual inactive conformation of the mitotic kinase Nek2: SAR and structural characterization.

  Journal of medicinal chemistry 20101111