57-06-7 | Allyl isothiocyanate

Packsize	Purity	Availability	Price	Discounted Price
5g	contains BHT as stabilizer, 95%	in stock	$76.00	$53.00
25g	contains BHT as stabilizer, 95%	in stock	$92.00	$65.00

Description

• Catalog Number: AG82736
• Chemical Name: Allyl isothiocyanate
• CAS Number: 57-06-7
• Molecular Formula: C4H5NS
• Molecular Weight: 99.1542
• MDL Number: MFCD00004822
• SMILES: C=CCN=C=S

Computed Properties

• Complexity: 81.5
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 6
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• XLogP3: 2.4

Literature

• The anthelminthic drug praziquantel is a selective agonist of the sensory transient receptor potential melastatin type 8 channel.

  Toxicology and applied pharmacology 20171201

• Sinigrin attenuates the progression of atherosclerosis in ApoE(-/-) mice fed a high-cholesterol diet potentially by inhibiting VCAM-1 expression.

  Chemico-biological interactions 20170625

• N-Acetyl-L-cysteine inhibits sulfur mustard-induced and TRPA1-dependent calcium influx.

  Archives of toxicology 20170501

• Potential roles for calcium-sensing receptor (CaSR) and transient receptor potential ankyrin-1 (TRPA1) in murine anorectic response to deoxynivalenol (vomitoxin).

  Archives of toxicology 20170101

• Calcium-Sensing Receptor and Transient Receptor Ankyrin-1 Mediate Emesis Induction by Deoxynivalenol (Vomitoxin).

  Toxicological sciences : an official journal of the Society of Toxicology 20170101

• Effects of Food Components That Activate TRPA1 Receptors on Mucosal Ion Transport in the Mouse Intestine.

  Nutrients 20161001

• Identification and functional characterization of four transient receptor potential ankyrin 1 variants in Apolygus lucorum (Meyer-Dür).

  Insect molecular biology 20160801

• Hepatoprotective effects of allyl isothiocyanate against carbon tetrachloride-induced hepatotoxicity in rat.

  Chemico-biological interactions 20160725

• Activation of Transient Receptor Potential Ankyrin-1 by Insoluble Particulate Material and Association with Asthma.

  American journal of respiratory cell and molecular biology 20151201

• A TRPA1 channel that senses thermal stimulus and irritating chemicals in Helicoverpa armigera.

  Insect molecular biology 20150801

• Dose response chemopreventive potential of allyl isothiocyanate against 7,12-dimethylbenz(a)anthracene induced mammary carcinogenesis in female Sprague-Dawley rats.

  Chemico-biological interactions 20150425

• Allyl isothiocyanate (AITC) inhibits pregnane X receptor (PXR) and constitutive androstane receptor (CAR) activation and protects against acetaminophen- and amiodarone-induced cytotoxicity.

  Archives of toxicology 20150101

• Functional expression of the transient receptor potential channel TRPA1, a sensor for toxic lung inhalants, in pulmonary epithelial cells.

  Chemico-biological interactions 20131205

• Suppression of dimerumic acid on hepatic fibrosis caused from carboxymethyl-lysine (CML) by attenuating oxidative stress depends on Nrf2 activation in hepatic stellate cells (HSCs).

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20131201

• Small molecule activators of the Nrf2-HO-1 antioxidant axis modulate heme metabolism and inflammation in BV2 microglia cells.

  Pharmacological research 20131001

• Activation of transient receptor potential ankyrin-1 (TRPA1) in lung cells by wood smoke particulate material.

  Chemical research in toxicology 20130520

• Stimulation of the chemosensory TRPA1 cation channel by volatile toxic substances promotes cell survival of small cell lung cancer cells.

  Biochemical pharmacology 20130201

• Effect of synthetic eel calcitonin, elcatonin, on cold and mechanical allodynia induced by oxaliplatin and paclitaxel in rats.

  European journal of pharmacology 20121205

• ERK-modulated intrinsic signaling and G(2)/M phase arrest contribute to the induction of apoptotic death by allyl isothiocyanate in MDA-MB-468 human breast adenocarcinoma cells.

  International journal of oncology 20121201

• Transient receptor potential ankyrin 1 activation enhances hapten sensitization in a T-helper type 2-driven fluorescein isothiocyanate-induced contact hypersensitivity mouse model.

  Toxicology and applied pharmacology 20121101

• Cellular and molecular responses of Salmonella Typhimurium to antimicrobial-induced stresses during the planktonic-to-biofilm transition.

  Letters in applied microbiology 20121001

• Removal of off-flavors from sea tangle (Laminaria japonica) extract by fermentation with Aspergillus oryzae.

  Bioresource technology 20121001

• Development of an antimicrobial sachet containing encapsulated allyl isothiocyanate to inactivate Escherichia coli O157:H7 on spinach leaves.

  International journal of food microbiology 20121001

• Opioid modulation of facial itch- and pain-related responses and grooming behavior in rats.

  Acta dermato-venereologica 20120901

• Differences in peripheral endocannabinoid modulation of scratching behavior in facial vs. spinally-innervated skin.

  Neuropharmacology 20120901

• Analysis of transient receptor potential ankyrin 1 (TRPA1) in frogs and lizards illuminates both nociceptive heat and chemical sensitivities and coexpression with TRP vanilloid 1 (TRPV1) in ancestral vertebrates.

  The Journal of biological chemistry 20120831

• Comparison of TRPA1-versus TRPV1-mediated cough in guinea pigs.

  European journal of pharmacology 20120815

• The role of transient receptor potential ankyrin 1 (TRPA1) receptor activation in hydrogen-sulphide-induced CGRP-release and vasodilation.

  European journal of pharmacology 20120815

• Structural influence of isothiocyanates on expression of cytochrome P450, phase II enzymes, and activation of Nrf2 in primary rat hepatocytes.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120801

• Suppression of TRIF-dependent signaling pathway of toll-like receptors by allyl isothiocyanate in RAW 264.7 macrophages.

  International immunopharmacology 20120801

• Inactivation of salmonella on tomato stem scars by edible chitosan and organic Acid coatings.

  Journal of food protection 20120801

• Hydrogen sulfide-induced mechanical hyperalgesia and allodynia require activation of both Cav3.2 and TRPA1 channels in mice.

  British journal of pharmacology 20120701

• Protective effects of isothiocyanates on blood-CSF barrier disruption induced by oxidative stress.

  American journal of physiology. Regulatory, integrative and comparative physiology 20120701

• Catalytic and structural diversity of the fluazifop-inducible glutathione transferases from Phaseolus vulgaris.

  Planta 20120601

• TRPA1 is functionally expressed in melanoma cells but is not critical for impaired proliferation caused by allyl isothiocyanate or cinnamaldehyde.

  Naunyn-Schmiedeberg's archives of pharmacology 20120601

• 5,6-EET is released upon neuronal activity and induces mechanical pain hypersensitivity via TRPA1 on central afferent terminals.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20120502

• Contact and fumigant toxicity of Armoracia rusticana essential oil, allyl isothiocyanate and related compounds to Dermatophagoides farinae.

  Pest management science 20120501

• Antimicrobial activity of cyclodextrin entrapped allyl isothiocyanate in a model system and packaged fresh-cut onions.

  Food microbiology 20120501

• Chemical reduction of the mycotoxin beauvericin using allyl isothiocyanate.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120501

• Inactivation of Salmonella on whole cantaloupe by application of an antimicrobial coating containing chitosan and allyl isothiocyanate.

  International journal of food microbiology 20120416

• Anti-inflammatory potential of allyl-isothiocyanate--role of Nrf2, NF-(κ) B and microRNA-155.

  Journal of cellular and molecular medicine 20120401

• Activation of TRPA1 by luminal stimuli induces EP4-mediated anion secretion in human and rat colon.

  American journal of physiology. Gastrointestinal and liver physiology 20120401

• Role of transient receptor potential ankyrin 1 in gastric accommodation in conscious guinea pigs.

  The Journal of pharmacology and experimental therapeutics 20120401

• Apolipoprotein E genotype affects tissue metallothionein levels: studies in targeted gene replacement mice.

  Genes & nutrition 20120401

• Activation of transient receptor potential A1 by a non-pungent capsaicin-like compound, capsiate.

  British journal of pharmacology 20120301

• Modulation of mouse gastrointestinal motility by allyl isothiocyanate, a constituent of cruciferous vegetables (Brassicaceae): evidence for TRPA1-independent effects.

  British journal of pharmacology 20120301

• Activation of transient receptor potential ankyrin 1 evokes nociception through substance P release from primary sensory neurons.

  Journal of neurochemistry 20120301

• Antidromic vasodilatation and the migraine mechanism.

  The journal of headache and pain 20120301

• Fetal ethanol exposure attenuates aversive oral effects of TrpV1, but not TrpA1 agonists in rats.

  Experimental biology and medicine (Maywood, N.J.) 20120301

• 3-(Adamantan-1-yl)-4-(prop-2-en-1-yl)-1H-1,2,4-triazole-5(4H)-thione.

  Acta crystallographica. Section E, Structure reports online 20120301

• Efficacy of washing with hydrogen peroxide followed by aerosolized antimicrobials as a novel sanitizing process to inactivate Escherichia coli O157:H7 on baby spinach.

  International journal of food microbiology 20120215

• Synthesis and biological evaluation of [6]-gingerol analogues as transient receptor potential channel TRPV1 and TRPA1 modulators.

  Bioorganic & medicinal chemistry letters 20120215

• Effects of microencapsulated Allyl isothiocyanate (AITC) on the extension of the shelf-life of Kimchi.

  International journal of food microbiology 20120201

• Allyl isothiocyanate as a potential inducer of paraoxonase-1--studies in cultured hepatocytes and in mice.

  IUBMB life 20120201

• The principal urinary metabolite of allyl isothiocyanate, N-acetyl-S-(N-allylthiocarbamoyl)cysteine, inhibits the growth and muscle invasion of bladder cancer.

  Carcinogenesis 20120201

• In vitro inhibitory activity of essential oil vapors against Ascosphaera apis.

  Natural product communications 20120201

• Apoptosis Induction in Primary Human Colorectal Cancer Cell Lines and Retarded Tumor Growth in SCID Mice by Sulforaphane.

  Evidence-based complementary and alternative medicine : eCAM 20120101

• TRPA1 channels regulate astrocyte resting calcium and inhibitory synapse efficacy through GAT-3.

  Nature neuroscience 20120101

• Essential oils in food preservation: mode of action, synergies, and interactions with food matrix components.

  Frontiers in microbiology 20120101

• Possible involvement of transient receptor potential channels in electrophile-induced insulin secretion from RINm5F cells.

  Biological & pharmaceutical bulletin 20120101

• Modeling effective dosages in hormetic dose-response studies.

  PloS one 20120101

• Warmth suppresses and desensitizes damage-sensing ion channel TRPA1.

  Molecular pain 20120101

• The safety of cruciferous plants in humans: a systematic review.

  Journal of biomedicine & biotechnology 20120101

• TRPA1 contributes to the acute inflammatory response and mediates carrageenan-induced paw edema in the mouse.

  Scientific reports 20120101

• Preparation and characterization of solid lipid nanoparticles loaded with frankincense and myrrh oil.

  International journal of nanomedicine 20120101

• The Role of TRP Proteins in Mast Cells.

  Frontiers in immunology 20120101

• Expression of transient receptor potential ankyrin 1 (TRPA1) and its role in insulin release from rat pancreatic beta cells.

  PloS one 20120101

• Etodolac blocks the allyl isothiocyanate-induced response in mouse sensory neurons by selective TRPA1 activation.

  Pharmacology 20120101

• Real-time analysis of sulfur-containing volatiles in Brassica plants infested with root-feeding Delia radicum larvae using proton-transfer reaction mass spectrometry.

  AoB PLANTS 20120101

• Antimicrobial activities of isothiocyanates against Campylobacter jejuni isolates.

  Frontiers in cellular and infection microbiology 20120101

• Synthesis and in vitro antimicrobial study of 4-thiazolidinone containing sulfanilamide.

  Acta poloniae pharmaceutica 20120101

• Artepillin C, a major ingredient of Brazilian propolis, induces a pungent taste by activating TRPA1 channels.

  PloS one 20120101

• TRP-channel-specific cutaneous eicosanoid release patterns.

  Pain 20111201

• Influence of NaCl and NaNO3 on sinigrin hydrolysis by foodborne bacteria.

  Journal of food protection 20111201

• Allyl isothiocyanate (AITC) induces stomatal closure in Arabidopsis.

  Plant, cell & environment 20111101

• Nitro-oleic acid targets transient receptor potential (TRP) channels in capsaicin sensitive afferent nerves of rat urinary bladder.

  Experimental neurology 20111101

• TRPV1 and TRPA1 stimulation induces MUC5B secretion in the human nasal airway in vivo.

  Clinical physiology and functional imaging 20111101

• Differentially expressed cDNAs in Alternaria alternata treated with 2-propenyl isothiocyanate.

  Microbiological research 20111020

• The effect of menthol vapor on nasal sensitivity to chemical irritation.

  Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20111001

• Expression of functional TRPA1 receptor on human lung fibroblast and epithelial cells.

  Journal of receptor and signal transduction research 20111001

• Preferential activation of the vagal nodose nociceptive subtype by TRPA1 agonists in the guinea pig esophagus.

  Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20111001

• Transient receptor potential A1 channels: insights into cough and airway inflammatory disease.

  Chest 20111001

• Comparative efficacy of plant-derived essential oils for managing ambrosia beetles (Coleoptera: Curculionidae: Scolytinae) and their corresponding mass spectral characterization.

  Journal of economic entomology 20111001

• Allyl isothiocyanate arrests cancer cells in mitosis, and mitotic arrest in turn leads to apoptosis via Bcl-2 protein phosphorylation.

  The Journal of biological chemistry 20110916

• Facial injections of pruritogens or algogens elicit distinct behavior responses in rats and excite overlapping populations of primary sensory and trigeminal subnucleus caudalis neurons.

  Journal of neurophysiology 20110901

• Activation characteristics of transient receptor potential ankyrin 1 and its role in nociception.

  American journal of physiology. Cell physiology 20110901

• Design and pharmacological evaluation of PF-4840154, a non-electrophilic reference agonist of the TrpA1 channel.

  Bioorganic & medicinal chemistry letters 20110815

• Transient receptor potential ankyrin 1 is expressed by inhibitory motoneurons of the mouse intestine.

  Gastroenterology 20110801

• Smelling the wood from the trees: non-linear parasitoid responses to volatile attractants produced by wild and cultivated cabbage.

  Journal of chemical ecology 20110801

• TRPA1 contributes to specific mechanically activated currents and sensory neuron mechanical hypersensitivity.

  The Journal of physiology 20110715

• In vitro and in vivo antifungal activity of synthetic pure isothiocyanates against Sclerotinia sclerotiorum.

  Pest management science 20110701

• Transient receptor potential (TRP) channels as drug targets for diseases of the digestive system.

  Pharmacology & therapeutics 20110701

• Ruminal methane inhibition potential of various pure compounds in comparison with garlic oil as determined with a rumen simulation technique (Rusitec).

  The British journal of nutrition 20110701

• The cap'n'collar transcription factor Nrf2 mediates both intrinsic resistance to environmental stressors and an adaptive response elicited by chemopreventive agents that determines susceptibility to electrophilic xenobiotics.

  Chemico-biological interactions 20110630

• Intragastric administration of allyl isothiocyanate increases carbohydrate oxidation via TRPV1 but not TRPA1 in mice.

  American journal of physiology. Regulatory, integrative and comparative physiology 20110601

• Enhanced responses of lumbar superficial dorsal horn neurons to intradermal PAR-2 agonist but not histamine in a mouse hindpaw dry skin itch model.

  Journal of neurophysiology 20110601

• The cannabinoid WIN 55,212-2-mediated protection of dentate gyrus granule cells is driven by CB1 receptors and modulated by TRPA1 and Cav 2.2 channels.

  Hippocampus 20110501

• Properties and therapeutic potential of transient receptor potential channels with putative roles in adversity: focus on TRPC5, TRPM2 and TRPA1.

  Current drug targets 20110501

• Propofol restores transient receptor potential vanilloid receptor subtype-1 sensitivity via activation of transient receptor potential ankyrin receptor subtype-1 in sensory neurons.

  Anesthesiology 20110501

• TRPA1 is required for histamine-independent, Mas-related G protein-coupled receptor-mediated itch.

  Nature neuroscience 20110501

• Transient receptor potential (TRP) A1 activated currents in TRPV1 and cholecystokinin-sensitive cranial visceral afferent neurons.

  Brain research 20110406

• The pore properties of human nociceptor channel TRPA1 evaluated in single channel recordings.

  Biochimica et biophysica acta 20110401

• Allyl isothiocyanate regulates caspase-1/receptor interacting protein-2 expression.

  International immunopharmacology 20110401

• Allyl isothiocyanates and cinnamaldehyde potentiate miniature excitatory postsynaptic inputs in the supraoptic nucleus in rats.

  European journal of pharmacology 20110325

• Allyl-, butyl- and phenylethyl-isothiocyanate activate Nrf2 in cultured fibroblasts.

  Pharmacological research 20110301

• Inactivation of Salmonella in liquid egg albumen by antimicrobial bottle coatings infused with allyl isothiocyanate, nisin and zinc oxide nanoparticles.

  Journal of applied microbiology 20110301

• Larvicidal activity of Myrtaceae essential oils and their components against Aedes aegypti, acute toxicity on Daphnia magna, and aqueous residue.

  Journal of medical entomology 20110301

• Selective depletion of mutant p53 by cancer chemopreventive isothiocyanates and their structure-activity relationships.

  Journal of medicinal chemistry 20110210

• Inhibition of virulence potential of Vibrio cholerae by natural compounds.

  The Indian journal of medical research 20110201

• The role of N-methyl-D-aspartate receptor subunits in the rat thalamic mediodorsal nucleus during central sensitization.

  Brain research 20110131

• A cell-based impedance assay for monitoring transient receptor potential (TRP) ion channel activity.

  Biosensors & bioelectronics 20110115

• Optimization of ultrasonic-stimulated solvent extraction of sinigrin from Indian mustard seed (Brassica Juncea L.) using response surface methodology.

  Phytochemical analysis : PCA 20110101

• Transient receptor potential A1 channel contributes to activation of the muscle reflex.

  American journal of physiology. Heart and circulatory physiology 20110101

• Male Phyllotreta striolata (F.) produce an aggregation pheromone: identification of male-specific compounds and interaction with host plant volatiles.

  Journal of chemical ecology 20110101

• The role of proboscis of the malaria vector mosquito Anopheles stephensi in host-seeking behavior.

  Parasites & vectors 20110101

• Inhibition of TRPA1 channel activity in sensory neurons by the glial cell line-derived neurotrophic factor family member, artemin.

  Molecular pain 20110101

• Benzyl isothiocyanate, a major component from the roots of Salvadora persica is highly active against Gram-negative bacteria.

  PloS one 20110101

• Pharmacological blockade of TRPM8 ion channels alters cold and cold pain responses in mice.

  PloS one 20110101

• TRP Channels as Sensors and Signal Integrators of Redox Status Changes.

  Frontiers in pharmacology 20110101

• Allyl isothiocyanate induced stress response in Caenorhabditis elegans.

  BMC research notes 20110101

• Toxic effects of a horseradish extract and allyl isothiocyanate in the urinary bladder after 13-week administration in drinking water to F344 rats.

  The Journal of toxicological sciences 20110101

• Use of brassica plants in the phytoremediation and biofumigation processes.

  International journal of molecular sciences 20110101

• [Antibacterial activity of essential oil vapor for histamine-producing bacteria].

  Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20110101

• Dietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cells.

  Clinical epigenetics 20110101

• Acetaminophen, via its reactive metabolite N-acetyl-p-benzo-quinoneimine and transient receptor potential ankyrin-1 stimulation, causes neurogenic inflammation in the airways and other tissues in rodents.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20101201

• Allyl isothiocyanate-rich mustard seed powder inhibits bladder cancer growth and muscle invasion.

  Carcinogenesis 20101201

• Determination of new biomarkers to monitor the dietary consumption of isothiocyanates.

  Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20101201

• Determination of amoxapine and nortriptyline in blood plasma and serum by salt-assisted liquid-liquid microextraction and high-performance liquid chromatography.

  Journal of separation science 20101201

• Overexpression of human transient receptor potential M5 upregulates endogenous human transient receptor potential A1 in a stable HEK cell line.

  Assay and drug development technologies 20101201

• 4-Allyl-3-(2-methyl-4-quinol-yl)-1H-1,2,4-triazole-5(4H)-thione.

  Acta crystallographica. Section E, Structure reports online 20101201

• Facial injections of pruritogens and algogens excite partly overlapping populations of primary and second-order trigeminal neurons in mice.

  Journal of neurophysiology 20101101

• Differential itch- and pain-related behavioral responses and µ-opoid modulation in mice.

  Acta dermato-venereologica 20101101

• Analogues of morphanthridine and the tear gas dibenz[b,f][1,4]oxazepine (CR) as extremely potent activators of the human transient receptor potential ankyrin 1 (TRPA1) channel.

  Journal of medicinal chemistry 20101014

• Calcium transient evoked by TRPV1 activators is enhanced by tumor necrosis factor-{alpha} in rat pulmonary sensory neurons.

  American journal of physiology. Lung cellular and molecular physiology 20101001

• Drosophila TRPA1 channel is required to avoid the naturally occurring insect repellent citronellal.

  Current biology : CB 20100928

• Evidence for the pathophysiological relevance of TRPA1 receptors in the cardiovascular system in vivo.

  Cardiovascular research 20100901

• Multidirectional time-dependent effect of sinigrin and allyl isothiocyanate on metabolic parameters in rats.

  Plant foods for human nutrition (Dordrecht, Netherlands) 20100901

• Mortality and behavior in Heterodera glycines juveniles following exposure to isothiocyanate compounds.

  Journal of nematology 20100901

• Transient receptor potential A1 is involved in cold-induced contraction in the isolated rat colon smooth muscle.

  Sheng li xue bao : [Acta physiologica Sinica] 20100825

• Allyl isothiocyanate triggers G2/M phase arrest and apoptosis in human brain malignant glioma GBM 8401 cells through a mitochondria-dependent pathway.

  Oncology reports 20100801

• Allyl isothiocyanate-induced changes in the distribution of white blood cells in rats.

  The Journal of toxicological sciences 20100801

• Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents.

  Journal of medicinal chemistry 20100722

• Chemo-nociceptive signalling from the colon is enhanced by mild colitis and blocked by inhibition of transient receptor potential ankyrin 1 channels.

  British journal of pharmacology 20100701

• Use of natural antimicrobials to increase antibiotic susceptibility of drug resistant bacteria.

  International journal of food microbiology 20100615

• Rb+ efflux assay for assessment of non-selective cation channel activities.

  Assay and drug development technologies 20100601

• Removing the mustard oil bomb from seeds: transgenic ablation of myrosin cells in oilseed rape (Brassica napus) produces MINELESS seeds.

  Journal of experimental botany 20100601

• Nitro-oleic acid inhibits firing and activates TRPV1- and TRPA1-mediated inward currents in dorsal root ganglion neurons from adult male rats.

  The Journal of pharmacology and experimental therapeutics 20100601

• Dynamic changes in the TRPA1 selectivity filter lead to progressive but reversible pore dilation.

  American journal of physiology. Cell physiology 20100601

• TRPA1-expressing primary afferents synapse with a morphologically identified subclass of substantia gelatinosa neurons in the adult rat spinal cord.

  The European journal of neuroscience 20100601

• Stability and antimicrobial activity of allyl isothiocyanate during long-term storage in an oil-in-water emulsion.

  Journal of food science 20100601

• [Effects of pulpal inflammation on the activities of periodontal mechanoreceptive afferent fibers].

  Kokubyo Gakkai zasshi. The Journal of the Stomatological Society, Japan 20100601

• [Field sampling methods for earthworm: a review].

  Ying yong sheng tai xue bao = The journal of applied ecology 20100601

• Transient receptor potential A1 and cannabinoid receptor activity in human normal and hyperplastic prostate: relation to nerves and interstitial cells.

  European urology 20100501

• TRPA1 receptor induced relaxation of the human urethra involves TRPV1 and cannabinoid receptor mediated signals, and cyclooxygenase activation.

  The Journal of urology 20100501

• Preservation of acidified cucumbers with a natural preservative combination of fumaric acid and allyl isothiocyanate that target lactic acid bacteria and yeasts.

  Journal of food science 20100501

• Antimicrobial activity of phenolics and glucosinolate hydrolysis products and their synergy with streptomycin against pathogenic bacteria.

  Medicinal chemistry (Shariqah (United Arab Emirates)) 20100501

• New biomarkers for monitoring the levels of isothiocyanates in humans.

  Chemical research in toxicology 20100419

• Behavioral evidence of thermal hyperalgesia and mechanical allodynia induced by intradermal cinnamaldehyde in rats.

  Neuroscience letters 20100412

• A dietary agonist of transient receptor potential cation channel V3 elicits endothelium-dependent vasodilation.

  Molecular pharmacology 20100401

• Biological profile of erucin: a new promising anticancer agent from cruciferous vegetables.

  Toxins 20100401

• Analysis of Drosophila TRPA1 reveals an ancient origin for human chemical nociception.

  Nature 20100325

• Activation of TRPA1 channels by fenamate nonsteroidal anti-inflammatory drugs.

  Pflugers Archiv : European journal of physiology 20100301

• Active packaging of fresh chicken breast, with allyl isothiocyanate (AITC) in combination with modified atmosphere packaging (MAP) to control the growth of pathogens.

  Journal of food science 20100301

• Evaluation of natural antimicrobials on typical meat spoilage bacteria in vitro and in vacuum-packed pork meat.

  Journal of food science 20100301

• Inhibition of bladder cancer development by allyl isothiocyanate.

  Carcinogenesis 20100201

• Multiple cation channels mediate increases in intracellular calcium induced by the volatile irritant, trans-2-pentenal in rat trigeminal neurons.

  Cellular and molecular neurobiology 20100101

• Enhanced activation of the transient receptor potential channel TRPA1 by ajoene, an allicin derivative.

  Neuroscience research 20100101

• Allyl isothiocyanate as a cancer chemopreventive phytochemical.

  Molecular nutrition & food research 20100101

• The roles of iPLA2, TRPM8 and TRPA1 in chemically induced cold hypersensitivity.

  Molecular pain 20100101

• Allyl isothiocyanate that induces GST and UGT expression confers oxidative stress resistance on C. elegans, as demonstrated by nematode biosensor.

  PloS one 20100101

• TRPA1 modulation of spontaneous and mechanically evoked firing of spinal neurons in uninjured, osteoarthritic, and inflamed rats.

  Molecular pain 20100101

• Immunochemical detection of food-derived isothiocyanate as a lysine conjugate.

  Bioscience, biotechnology, and biochemistry 20100101

• Effect of allyl isothiocyanate (AITC) in both nitrite- and nitrosamine-induced cell death, production of reactive oxygen species, and DNA damage by the single-cell gel electrophoresis (SCGE): does it have any protective effect on HepG2 cells?

  International journal of toxicology 20100101

• Transcript and protein profiling identify candidate gene sets of potential adaptive significance in New Zealand Pachycladon.

  BMC evolutionary biology 20100101

• In vivo patch-clamp analysis of response properties of rat primary somatosensory cortical neurons responding to noxious stimulation of the facial skin.

  Molecular pain 20100101

• Stimuli of sensory-motor nerves terminate arterial contractile effects of endothelin-1 by CGRP and dissociation of ET-1/ET(A)-receptor complexes.

  PloS one 20100101

• Isothiocyanates induce oxidative stress and suppress the metastasis potential of human non-small cell lung cancer cells.

  BMC cancer 20100101

• Neuroinflammation in inflammatory bowel disease.

  Journal of neuroinflammation 20100101

• Nociceptive stimulation induces expression of Arc/Arg3.1 in the spinal cord with a preference for neurons containing enkephalin.

  Molecular pain 20100101

• Galangal pungent component, 1'-acetoxychavicol acetate, activates TRPA1.

  Bioscience, biotechnology, and biochemistry 20100101

• Menthol response and adaptation in nociceptive-like and nonnociceptive-like neurons: role of protein kinases.

  Molecular pain 20100101

• Dissociation of μ- and δ-opioid inhibition of glutamatergic synaptic transmission in superficial dorsal horn.

  Molecular pain 20100101

• Allyl isothiocyanate induces G2/M arrest in human colorectal adenocarcinoma SW620 cells through down-regulation of Cdc25B and Cdc25C.

  Molecular medicine reports 20100101

• Small intestinal cannabinoid receptor changes following a single colonic insult with oil of mustard in mice.

  Frontiers in pharmacology 20100101

• Effect of resiniferatoxin on glutamatergic spontaneous excitatory synaptic transmission in substantia gelatinosa neurons of the adult rat spinal cord.

  Neuroscience 20091229

• Effects of transient receptor potential (TRP) channel agonists and antagonists on slowly adapting type II mechanoreceptors in the rat sinus hair follicle.

  Journal of the peripheral nervous system : JPNS 20091201

• [Antimicrobial efficacy of benzyl isothiocyanate].

  Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20091201

• QGP-1 cells release 5-HT via TRPA1 activation; a model of human enterochromaffin cells.

  Molecular and cellular biochemistry 20091101

• Transient receptor potential ankyrin receptor 1 is a novel target for pro-tussive agents.

  British journal of pharmacology 20091101

• Differentiation dependent expression of TRPA1 and TRPM8 channels in IMR-32 human neuroblastoma cells.

  Journal of cellular physiology 20091001

• TRPA1 agonists delay gastric emptying in rats through serotonergic pathways.

  Naunyn-Schmiedeberg's archives of pharmacology 20091001

• Responses of the crucifer flea beetle to Brassica volatiles in an olfactometer.

  Environmental entomology 20091001

• Inactivation of Escherichia coli O157:H7 on the intact and damaged portions of lettuce and spinach leaves by using allyl isothiocyanate, carvacrol, and cinnamaldehyde in vapor phase.

  Journal of food protection 20091001

• Extraction of allyl isothiocyanate from horseradish (Armoracia rusticana) and its fumigant insecticidal activity on four stored-product pests of paddy.

  Pest management science 20090901

• Molecular cloning and characterization of dog TRPA1 and AITC stimulate the gastrointestinal motility through TRPA1 in conscious dogs.

  European journal of pharmacology 20090901

• [Development of allyl isothiocyanate detection kit].

  Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology 20090901

• Volatile constituents throughout Brassica oleracea L. Var. acephala germination.

  Journal of agricultural and food chemistry 20090812

• Acute and chronic effects of neurotrophic factors BDNF and GDNF on responses mediated by thermo-sensitive TRP channels in cultured rat dorsal root ganglion neurons.

  Brain research 20090811

• Transient receptor potential A1 increase glutamate release on brain stem neurons.

  Neuroreport 20090715

• Miogadial and miogatrial with alpha,beta-unsaturated 1,4-dialdehyde moieties--novel and potent TRPA1 agonists.

  Life sciences 20090703

• Essential role for the putative S6 inner pore region in the activation gating of the human TRPA1 channel.

  Biochimica et biophysica acta 20090701

• Degradation and sorption of 2-propenyl and benzyl isothiocyanate in soil.

  Environmental toxicology and chemistry 20090601

• Potency of isothiocyanates to induce luciferase reporter gene expression via the electrophile-responsive element from murine glutathione S-transferase Ya.

  Toxicology in vitro : an international journal published in association with BIBRA 20090601

• Primary afferents with TRPM8 and TRPA1 profiles target distinct subpopulations of rat superficial dorsal horn neurones.

  British journal of pharmacology 20090601

• Peripheral and central levels in nasal trigeminal sensitization and desensitization.

  Rhinology 20090601

• Enzymatic inhibition by allyl isothiocyanate and factors affecting its antimicrobial action against Escherichia coli O157:H7.

  International journal of food microbiology 20090531

• Interactive effects of sulfur and nitrogen supply on the concentration of sinigrin and allyl isothiocyanate in Indian mustard (Brassica juncea L.).

  Journal of agricultural and food chemistry 20090513

• Diallyl sulfides in garlic activate both TRPA1 and TRPV1.

  Biochemical and biophysical research communications 20090508

• TREKing noxious thermosensation.

  The EMBO journal 20090506

• TRPV1-mediated itch in seasonal allergic rhinitis.

  Allergy 20090501

• Intragastric administration of TRPV1, TRPV3, TRPM8, and TRPA1 agonists modulates autonomic thermoregulation in different manners in mice.

  Bioscience, biotechnology, and biochemistry 20090501

• Endothelium-dependent cerebral artery dilation mediated by TRPA1 and Ca2+-Activated K+ channels.

  Circulation research 20090424

• Lateral hypothalamic-induced alpha-adrenoceptor modulation occurs in a model of inflammatory pain in rats.

  Biological research for nursing 20090401

• Activation of lumbar spinal wide-dynamic range neurons by a sanshool derivative.

  Journal of neurophysiology 20090401

• Nitrooleic acid, an endogenous product of nitrative stress, activates nociceptive sensory nerves via the direct activation of TRPA1.

  Molecular pharmacology 20090401

• Covalent modification of lysine residues by allyl isothiocyanate in physiological conditions: plausible transformation of isothiocyanate from thiol to amine.

  Chemical research in toxicology 20090316

• Transient receptor potential A1 (TRPA1) activity in the human urethra--evidence for a functional role for TRPA1 in the outflow region.

  European urology 20090301

• Zinc activates damage-sensing TRPA1 ion channels.

  Nature chemical biology 20090301

• Antiangiogenic and proapoptotic activities of allyl isothiocyanate inhibit ascites tumor growth in vivo.

  Integrative cancer therapies 20090301

• Resiniferatoxin mediated ablation of TRPV1+ neurons removes TRPA1 as well.

  The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20090301

• TRPA1 activation by lidocaine in nerve terminals results in glutamate release increase.

  Biochemical and biophysical research communications 20090220

• Ultraviolet light and photosensitising agents activate TRPA1 via generation of oxidative stress.

  Cell calcium 20090201

• TRPA1 in bradykinin-induced mechanical hypersensitivity of vagal C fibers in guinea pig esophagus.

  American journal of physiology. Gastrointestinal and liver physiology 20090201

• Inactivation of Salmonella and Escherichia coli O157:H7 on sliced and whole tomatoes by allyl isothiocyanate, carvacrol, and cinnamaldehyde in vapor phase.

  Journal of food protection 20090201

• Allyl isothiocyanate influences cell adhesion, migration and metalloproteinase gene expression in SK-Hep1 cells.

  Experimental biology and medicine (Maywood, N.J.) 20090101

• Pore dilation occurs in TRPA1 but not in TRPM8 channels.

  Molecular pain 20090101

• Isothiocyanate profile and selective antibacterial activity of root, stem, and leaf extracts derived from Raphanus sativus L.

  Foodborne pathogens and disease 20090101

• High concentrations of morphine sensitize and activate mouse dorsal root ganglia via TRPV1 and TRPA1 receptors.

  Molecular pain 20090101

• Impairment by allyl isothiocyanate of gastric epithelial wound repair through inhibition of ion transporters.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20081201

• Efficacy and side effects of five sampling methods for soil earthworms (Annelida, Lumbricidae).

  Ecotoxicology and environmental safety 20081001

• Comparative innate responses of the aphid parasitoid Diaeretiella rapae to alkenyl glucosinolate derived isothiocyanates, nitriles, and epithionitriles.

  Journal of chemical ecology 20081001

• In vivo birthdating by BAPTISM reveals that trigeminal sensory neuron diversity depends on early neurogenesis.

  Development (Cambridge, England) 20081001

• Drosophila painless is a Ca2+-requiring channel activated by noxious heat.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20081001

• TRPA1 agonists--allyl isothiocyanate and cinnamaldehyde--induce adrenaline secretion.

  Bioscience, biotechnology, and biochemistry 20081001

• Regiospecifically alpha-13C-labeled porphyrins for studies of ground-state hole transfer in multiporphyrin arrays.

  The Journal of organic chemistry 20080919

• Tear gasses CN, CR, and CS are potent activators of the human TRPA1 receptor.

  Toxicology and applied pharmacology 20080901

• Activation of transient receptor potential A1 channels by mustard oil, tetrahydrocannabinol and Ca2+ reveals different functional channel states.

  Neuroscience 20080717

• Inhibition of transient receptor potential A1 channel by phosphatidylinositol-4,5-bisphosphate.

  American journal of physiology. Cell physiology 20080701

• [Devising a detector tube for allyl isothiocyanate].

  Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology 20080701

• TRPV2 is activated by cannabidiol and mediates CGRP release in cultured rat dorsal root ganglion neurons.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20080611

• Effect of free-SH containing compounds on allyl isothiocyanate antimicrobial activity against Escherichia coli O157:H7.

  Journal of food science 20080601

• Inflammation reduces mechanical thresholds in a population of transient receptor potential channel A1-expressing nociceptors in the rat.

  The European journal of neuroscience 20080601

• Molecular determinants of species-specific activation or blockade of TRPA1 channels.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20080507

• Phospholipase C and protein kinase A mediate bradykinin sensitization of TRPA1: a molecular mechanism of inflammatory pain.

  Brain : a journal of neurology 20080501

• Homologous and heterologous desensitization of capsaicin and mustard oil responses utilize different cellular pathways in nociceptors.

  Pain 20080401

• Influence of cooking duration of cabbage and presence of colonic microbiota on the excretion of N-acetylcysteine conjugates of allyl isothiocyanate and bioactivity of phase 2 enzymes in F344 rats.

  The British journal of nutrition 20080401

• Activation of TRPA1 by farnesyl thiosalicylic acid.

  Molecular pharmacology 20080401

• Thymol and related alkyl phenols activate the hTRPA1 channel.

  British journal of pharmacology 20080401

• Pronociceptive response elicited by TRPA1 receptor activation in mice.

  Neuroscience 20080318

• Transient receptor potential A1 is a sensory receptor for multiple products of oxidative stress.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20080305

• Protective effects of isothiocyanates alone or in combination with vitamin C towards N-nitrosodibutylamine or N-nitrosopiperidine-induced oxidative DNA damage in the single-cell gel electrophoresis (SCGE)/HepG2 assay.

  Journal of applied toxicology : JAT 20080301

• Activation of transient receptor potential ankyrin 1 by hydrogen peroxide.

  The European journal of neuroscience 20080301

• ThermoTRP channels in nociceptors: taking a lead from capsaicin receptor TRPV1.

  Current neuropharmacology 20080301

• Herbal compounds and toxins modulating TRP channels.

  Current neuropharmacology 20080301

• Effects of TRPA1 agonists mustard oil and cinnamaldehyde on lumbar spinal wide-dynamic range neuronal responses to innocuous and noxious cutaneous stimuli in rats.

  Journal of neurophysiology 20080201

• Editorial comment on: distribution and function of the hydrogen sulfide-sensitive TRPA1 ion channel in rat urinary bladder.

  European urology 20080201

• Prostaglandin-induced activation of nociceptive neurons via direct interaction with transient receptor potential A1 (TRPA1).

  Molecular pharmacology 20080201

• Distribution and function of the hydrogen sulfide-sensitive TRPA1 ion channel in rat urinary bladder.

  European urology 20080201

• Partial restoration of mutant enzyme homeostasis in three distinct lysosomal storage disease cell lines by altering calcium homeostasis.

  PLoS biology 20080201

• Transient receptor potential A1 mediates an osmotically activated ion channel.

  The European journal of neuroscience 20080201

• Cannabinoids desensitize capsaicin and mustard oil responses in sensory neurons via TRPA1 activation.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20080130

• TRPA1 channel activation induces cholecystokinin release via extracellular calcium.

  FEBS letters 20080123

• Modulation of oral heat and cold pain by irritant chemicals.

  Chemical senses 20080101

• Predicting survival of Escherichia coli O157:H7 in dry fermented sausage using artificial neural networks.

  Journal of food protection 20080101

• Responses of the ciliates tetrahymena and paramecium to vertebrate odorants and tastants.

  The Journal of eukaryotic microbiology 20080101

• Molecular and cellular limits to somatosensory specificity.

  Molecular pain 20080101

• Citral sensing by Transient [corrected] receptor potential channels in dorsal root ganglion neurons.

  PloS one 20080101

• Cutaneous nociception evoked by 15-delta PGJ2 via activation of ion channel TRPA1.

  Molecular pain 20080101

• Fumigant antifungal activity of essential oil components from Acorus gramineus against three phytopathogenic fungi.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20080101

• HC-030031, a TRPA1 selective antagonist, attenuates inflammatory- and neuropathy-induced mechanical hypersensitivity.

  Molecular pain 20080101

• Contractile effect of TRPA1 receptor agonists in the isolated mouse intestine.

  European journal of pharmacology 20071208

• Inhibition of endothelial cell differentiation and proinflammatory cytokine production during angiogenesis by allyl isothiocyanate and phenyl isothiocyanate.

  Integrative cancer therapies 20071201

• Flower vs. leaf feeding by Pieris brassicae: glucosinolate-rich flower tissues are preferred and sustain higher growth rate.

  Journal of chemical ecology 20071001

• Glutathione- and thioredoxin-related enzymes are modulated by sulfur-containing chemopreventive agents.

  Biological chemistry 20071001

• Impairment by activation of TRPA1 of gastric epithelial restitution in a wound model using RGM1 cell monolayer.

  Inflammopharmacology 20071001

• Transient receptor potential channel A1 involved in sensory transduction of rat urinary bladder through C-fiber pathway.

  Urology 20071001

• A pharmacological study of slowly adapting mechanoreceptors responsive to cold thermal stimulation.

  Neuroscience 20070824

• Astroglial glutamate-glutamine shuttle is involved in central sensitization of nociceptive neurons in rat medullary dorsal horn.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20070822

• 4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1.

  Proceedings of the National Academy of Sciences of the United States of America 20070814

• Influence of cabbage processing methods and prebiotic manipulation of colonic microflora on glucosinolate breakdown in man.

  The British journal of nutrition 20070801

• Characterization of spinal alpha-adrenergic modulation of nociceptive transmission and hyperalgesia throughout postnatal development in rats.

  British journal of pharmacology 20070801

• Cold sensitivity of recombinant TRPA1 channels.

  Brain research 20070730

• Sensitization of TRPA1 by PAR2 contributes to the sensation of inflammatory pain.

  The Journal of clinical investigation 20070702

• Requirement of a soluble intracellular factor for activation of transient receptor potential A1 by pungent chemicals: role of inorganic polyphosphates.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20070613

• Novel agonistic action of mustard oil on recombinant and endogenous porcine transient receptor potential V1 (pTRPV1) channels.

  Biochemical pharmacology 20070515

• Activation of TRPA1 channels by the fatty acid amide hydrolase inhibitor 3'-carbamoylbiphenyl-3-yl cyclohexylcarbamate (URB597).

  Molecular pharmacology 20070501

• Synthesis of new sugar derivatives from Stachys sieboldi Miq and antibacterial evaluation against Mycobacterium tuberculosis, Mycobacterium avium, and Staphylococcus aureus.

  Bioorganic & medicinal chemistry letters 20070501

• Methyl p-hydroxybenzoate causes pain sensation through activation of TRPA1 channels.

  British journal of pharmacology 20070501

• Effects of allyl isothiocyanate from horseradish on several experimental gastric lesions in rats.

  European journal of pharmacology 20070430

• Activation of TRPA1 channel facilitates excitatory synaptic transmission in substantia gelatinosa neurons of the adult rat spinal cord.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20070418

• Mechanism of action and efficacy of seed meal-induced pathogen suppression differ in a brassicaceae species and time-dependent manner.

  Phytopathology 20070401

• TRPA1 is differentially modulated by the amphipathic molecules trinitrophenol and chlorpromazine.

  The Journal of biological chemistry 20070309

• Primary and secondary hyperalgesia can be differentiated by postnatal age and ERK activation in the spinal dorsal horn of the rat pup.

  Pain 20070301

• Allyl isothiocyanate (AITC) and phenyl isothiocyanate (PITC) inhibit tumour-specific angiogenesis by downregulating nitric oxide (NO) and tumour necrosis factor-alpha (TNF-alpha) production.

  Nitric oxide : biology and chemistry 20070301

• TRP channels as target sites for insecticides: physiology, pharmacology and toxicology.

  Invertebrate neuroscience : IN 20070301

• Transcriptional responses to exposure to the brassicaceous defence metabolites camalexin and allyl-isothiocyanate in the necrotrophic fungus Alternaria brassicicola.

  Molecular plant pathology 20070301

• Combined effect of volatile antimicrobial agents on the growth of Penicillium notatum.

  International journal of food microbiology 20070215

• Active spice-derived components can inhibit inflammatory responses of adipose tissue in obesity by suppressing inflammatory actions of macrophages and release of monocyte chemoattractant protein-1 from adipocytes.

  Life sciences 20070213

• Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines.

  Nature 20070201

• Influence of local treatments with capsaicin or allyl isothiocyanate in the sensitization phase of a fluorescein-isothiocyanate-induced contact sensitivity model.

  International archives of allergy and immunology 20070101

• MAK-4 and -5 supplemented diet inhibits liver carcinogenesis in mice.

  BMC complementary and alternative medicine 20070101

• Species spectrum of flea beetles (Phyllotreta spp., Coleoptera, Chrysomelidae) attracted to allyl isothiocyanate-baited traps.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20070101

• Species-specific pharmacology of Trichloro(sulfanyl)ethyl benzamides as transient receptor potential ankyrin 1 (TRPA1) antagonists.

  Molecular pain 20070101

• Changes in glucosinolate concentrations, myrosinase activity, and production of metabolites of glucosinolates in cabbage (Brassica oleracea Var. capitata) cooked for different durations.

  Journal of agricultural and food chemistry 20061004

• Active packaging of cheese with allyl isothiocyanate, an alternative to modified atmosphere packaging.

  Journal of food protection 20061001

• Fumigant activity of plant essential oils and components from horseradish (Armoracia rusticana), anise (Pimpinella anisum) and garlic (Allium sativum) oils against Lycoriella ingenua (Diptera: Sciaridae).

  Pest management science 20060801

• Phenethyl isothiocyanate triggers apoptosis in Jurkat cells made resistant by the overexpression of Bcl-2.

  Cancer research 20060701

• [Studies on chemical components of essential oil of crude semen sinapis and roasted semen sinapis].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060701

• Contractile mechanisms coupled to TRPA1 receptor activation in rat urinary bladder.

  Biochemical pharmacology 20060628

• Impaired nociception and inflammatory pain sensation in mice lacking the prokineticin receptor PKR1: focus on interaction between PKR1 and the capsaicin receptor TRPV1 in pain behavior.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20060621

• Sensitivity to allyl isothiocyanate, dimethyl trisulfide, sinigrin, and cooked cauliflower consumption.

  Appetite 20060501

• Oregano, thyme and clove-derived flavors and skin sensitizers activate specific TRP channels.

  Nature neuroscience 20060501

• Invasive plant suppresses the growth of native tree seedlings by disrupting belowground mutualisms.

  PLoS biology 20060501

• Inhibitory effects of microencapsulated allyl isothiocyanate (AIT) against Escherichia coli O157:H7 in refrigerated, nitrogen packed, finely chopped beef.

  International journal of food microbiology 20060401

• Allyl isothiocyanate and its N-acetylcysteine conjugate suppress metastasis via inhibition of invasion, migration, and matrix metalloproteinase-2/-9 activities in SK-Hep 1 human hepatoma cells.

  Experimental biology and medicine (Maywood, N.J.) 20060401

• ERK and JNK signaling pathways are involved in the regulation of activator protein 1 and cell death elicited by three isothiocyanates in human prostate cancer PC-3 cells.

  Carcinogenesis 20060301

• Molecular identification and functional characterization of a temperature-sensitive transient receptor potential channel (TRPM8) from canine.

  European journal of pharmacology 20060113

• Modest induction of phase 2 enzyme activity in the F-344 rat prostate.

  BMC cancer 20060101

• Induction of quinone reductase by allylisothiocyanate (AITC) and the N-acetylcysteine conjugate of AITC in Hepa1c1c7 mouse hepatoma cells.

  BioFactors (Oxford, England) 20060101

• Radioprotective activity of naturally occurring organosulfur compounds.

  Tumori 20060101

• Protective effects of isothiocyanates towards N-nitrosamine-induced DNA damage in the single-cell gel electrophoresis (SCGE)/HepG2 assay.

  Journal of applied toxicology : JAT 20060101

• Protective effects of isothiocyanates towards N-nitrosamine-induced DNA damage in the single-cell gel electrophoresis (SCGE)/HepG2 assay.

  Journal of applied toxicology : JAT 20060101

• Management of root knot nematodes in turfgrass using mustard formulations and biostimulants.

  Communications in agricultural and applied biological sciences 20060101

• Biofumigation: environmental impacts on the biological activity of diverse pure and plant-derived isothiocyanates.

  Pest management science 20051101

• Pheromonal activity of compounds identified from male Phyllotreta cruciferae: field tests of racemic mixtures, pure enantiomers, and combinations with allyl isothiocyanate.

  Journal of chemical ecology 20051101

• The role of c-Jun in the AP-1 activation induced by naturally occurring isothiocyanates.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20050901

• Responses of flea beetle Phyllotreta cruciferae to synthetic aggregation pheromone components and host plant volatiles in field trials.

  Journal of chemical ecology 20050801

• Ambient odors influence the amplitude and time course of visual distraction.

  Behavioral neuroscience 20050601

• Trigeminal sensitization and desensitization in the nasal cavity: a study of cross interactions.

  Rhinology 20050601

• Effects of Brussels sprout juice on the cell cycle and adhesion of human colorectal carcinoma cells (HT29) in vitro.

  Journal of agricultural and food chemistry 20050518

• Nociceptor and hair cell transducer properties of TRPA1, a channel for pain and hearing.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20050420

• Characterization of antimutagenic mechanism of 3-allyl-5-substituted 2-thiohydantoins against 2-amino-3-methylimidazo[4,5-f]quinoline.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20050401

• Use of mustard flour to inactivate Escherichia coli O157:H7 in ground beef under nitrogen flushed packaging.

  International journal of food microbiology 20050401

• Inactivation of Escherichia coli O157:H7 in packaged ground beef by allyl isothiocyanate.

  International journal of food microbiology 20050401

• Differential expression and stability of endogenous nuclear factor E2-related factor 2 (Nrf2) by natural chemopreventive compounds in HepG2 human hepatoma cells.

  Journal of biochemistry and molecular biology 20050331

• Biofumigant compounds released by field pennycress (Thlaspi arvense) seedmeal.

  Journal of chemical ecology 20050101

• How cold is it? TRPM8 and TRPA1 in the molecular logic of cold sensation.

  Molecular pain 20050101

• Effects of glucosinolates and their enzymatic hydrolysis products via myrosinase on the root-knot nematode Meloidogyne incognita (Kofoid et White) Chitw.

  Journal of agricultural and food chemistry 20041103

• Allyl-isothiocyanate causes mitotic block, loss of cell adhesion and disrupted cytoskeletal structure in HT29 cells.

  Carcinogenesis 20040801

• Bactericidal activity of wasabi (Wasabia japonica) against Helicobacter pylori.

  International journal of food microbiology 20040801

• Allergic contact dermatitis from allyl isothiocyanate in a Danish cohort of 259 selected patients.

  Contact dermatitis 20040801

• Mustard oil has differential effects on the response of trigeminal caudalis neurons to heat and acidity.

  Pain 20040701

• Induction of phase II detoxification enzymes in rats by plant-derived isothiocyanates: comparison of allyl isothiocyanate with sulforaphane and related compounds.

  Journal of agricultural and food chemistry 20040407

• Modulation of AP-1 by natural chemopreventive compounds in human colon HT-29 cancer cell line.

  Pharmaceutical research 20040401

• Modulatory properties of various natural chemopreventive agents on the activation of NF-kappaB signaling pathway.

  Pharmaceutical research 20040401

• Influence of nasal trigeminal stimuli on olfactory sensitivity.

  Comptes rendus biologies 20040401

• Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin.

  Neuron 20040325

• In vitro digestion of sinigrin and glucotropaeolin by single strains of Bifidobacterium and identification of the digestive products.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20040301

• Effects of ionized cyclodextrin on decomposition of allyl isothiocyanate in alkaline solutions.

  Bioscience, biotechnology, and biochemistry 20040201

• Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1.

  Nature 20040115

• Hydrolysis of glucosinolates to isothiocyanates after ingestion of raw or microwaved cabbage by human volunteers.

  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20040101

• Mustard oil induces a transient receptor potential vanilloid 1 receptor-independent neurogenic inflammation and a non-neurogenic cellular inflammatory component in mice.

  Neuroscience 20040101

• Bactericidal effects of Lactobacillus reuteri and allyl isothiocyanate on Escherichia coli O157:H7 in refrigerated ground beef.

  Journal of food protection 20031101

• Allyl isothiocyanate, a constituent of cruciferous vegetables, inhibits growth of PC-3 human prostate cancer xenografts in vivo.

  Carcinogenesis 20031001

• Comparison of human exposures to selected chemicals with thresholds from NTP carcinogenicity studies in rodents.

  Human & experimental toxicology 20030901

• Determination of aromatic primary amines at microg l(-1) level in environmental waters by gas chromatography-mass spectrometry involving N-allyl-n'-arylthiourea formation and their on-line pyrolysis to aryl isothiocyanates.

  Journal of chromatography. A 20030829

• Extracellular signaling-regulated kinase-1 and -2 (ERK 1/2) mediate referred hyperalgesia in a murine model of visceral pain.

  Brain research. Molecular brain research 20030819

• Influence of plant and bacterial myrosinase activity on the metabolic fate of glucosinolates in gnotobiotic rats.

  The British journal of nutrition 20030801

• Effect of naturally occurring isothiocyanates on the immune system.

  Immunopharmacology and immunotoxicology 20030801

• Oral irritation by mustard oil: self-desensitization and cross-desensitization with capsaicin.

  Chemical senses 20030701

• Effect of naturally occurring allyl and phenyl isothiocyanates in the inhibition of experimental pulmonary metastasis induced by B16F-10 melanoma cells.

  Fitoterapia 20030601

• Anti-tumour and anti-oxidant activity of naturally occurring isothiocyanates.

  Journal of experimental & clinical cancer research : CR 20030601

• A role for isothiocyanates in plant resistance against the specialist herbivore Pieris rapae.

  Journal of chemical ecology 20030601

• Sensitivity of Meloidogyne javanica and Tylenchulus semipenetrans to Isothiocyanates in Laboratory Assays.

  Phytopathology 20030601

• Allyl isothiocyanate, a constituent of cruciferous vegetables, inhibits proliferation of human prostate cancer cells by causing G2/M arrest and inducing apoptosis.

  Carcinogenesis 20030501

• Effects of mustard sprouts and allylisothiocyanate on benzo(a)pyrene-induced DNA damage in human-derived cells: a model study with the single cell gel electrophoresis/Hep G2 assay.

  Teratogenesis, carcinogenesis, and mutagenesis 20030101

• Antifungal activity of essential oils evaluated by two different application techniques against rye bread spoilage fungi.

  Journal of applied microbiology 20030101

• Non-conventional methods for the control of post-harvest pear diseases.

  Journal of applied microbiology 20030101

• Flavor-active compounds potentially implicated in cooked cauliflower acceptance.

  Journal of agricultural and food chemistry 20021023

• Deficits in visceral pain and referred hyperalgesia in Nav1.8 (SNS/PN3)-null mice.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20021001

• Sensitization and desensitization to allyl isothiocyanate (mustard oil) in the nasal cavity.

  Chemical senses 20020901

• Direct and simultaneous analysis of sinigrin and allyl isothiocyanate in mustard samples by high-performance liquid chromatography.

  Journal of agricultural and food chemistry 20020814

• Protective effects of Brussels sprouts towards B[a]P-induced DNA damage: a model study with the single-cell gel electrophoresis (SCGE)/Hep G2 assay.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20020801

• Lateralization in human nasal chemoreception: differences in bilateral electrodermal responses related to olfactory and trigeminal stimuli.

  Behavioural brain research 20020718

• Effect of naturally occurring organosulfur compounds on nitric oxide production in lipopolysaccharide-activated macrophages.

  Life sciences 20020614

• Metabolism of sinigrin (2-propenyl glucosinolate) by the human colonic microflora in a dynamic in vitro large-intestinal model.

  Carcinogenesis 20020601

• [Determination of isothiocyanates and related compounds in mustard extract and horseradish extract used as natural food additives].

  Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20020201

• Olfactory responses of Plutella xylostella natural enemies to host pheromone, larval frass, and green leaf cabbage volatiles.

  Journal of chemical ecology 20020101

• Glucosinolate breakdown products as insect fumigants and their effect on carbon dioxide emission of insects.

  BMC ecology 20020101

• Induction of histone acetylation and inhibition of growth of mouse erythroleukemia cells by S-allylmercaptocysteine.

  Nutrition and cancer 20020101

• Selective induction of phase II enzymes in the urinary bladder of rats by allyl isothiocyanate, a compound derived from Brassica vegetables.

  Nutrition and cancer 20020101

• Behavioral responses of adult female tobacco hornworms, Manduca sexta, to hostplant volatiles change with age and mating status.

  Journal of insect science (Online) 20020101

• Quality of odor and olfactory lateralization processes in humans.

  Neuroscience letters 20011201

• 4-(Methylthio)-3-butenyl isothiocyanate, a principal antimutagen in daikon (Raphanus sativus; Japanese white radish).

  Journal of agricultural and food chemistry 20011201

• Induction of histone acetylation in mouse erythroleukemia cells by some organosulfur compounds including allyl isothiocyanate.

  International journal of cancer 20010615

• Formation of allyl isothiocyanate from sinigrin in the digestive tract of rats monoassociated with a human colonic strain of Bacteroides thetaiotaomicron.

  FEMS microbiology letters 20010401

• Evaluation of volatile chemical treatments for lethality to Salmonella on alfalfa seeds and sprouts.

  Journal of food protection 20010401

• Signal transduction activated by the cancer chemopreventive isothiocyanates: cleavage of BID protein, tyrosine phosphorylation and activation of JNK.

  British journal of cancer 20010301

• Induction of histone acetylation in rat liver and hepatoma by organosulfur compounds including diallyl disulfide.

  Anticancer research 20010101

• Toxic effects of benzyl and allyl isothiocyanates and benzyl-isoform specific metabolites in the urinary bladder after a single intravesical application to rats.

  Toxicologic pathology 20010101

• Studies on the mechanism of the inhibition of human leukaemia cell growth by dietary isothiocyanates and their cysteine adducts in vitro.

  Biochemical pharmacology 20000715

• Reversible conjugation of isothiocyanates with glutathione catalyzed by human glutathione transferases.

  Biochemical and biophysical research communications 19950117