57044-25-4 | (R)-Glycidol

Packsize	Purity	Availability	Price	Discounted Price
1g	97%	in stock	$25.00	$17.00
10g	97%	in stock	$26.00	$18.00
25g	97%	in stock	$45.00	$32.00
100g	97%	in stock	$155.00	$108.00

Description

• Catalog Number: AB50965
• Chemical Name: (R)-Glycidol
• CAS Number: 57044-25-4
• Molecular Formula: C3H6O2
• Molecular Weight: 74.0785
• MDL Number: MFCD00074873
• SMILES: OC[C@@H]1CO1

Computed Properties

• Complexity: 35.9
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 5
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 1
• XLogP3: -0.9

Upstream Synthesis Route

The chiral compound (R)-Oxiran-2-ylmethanol, also known as (R)-glycidol, finds a crucial role in chemical synthesis as a versatile building block. Due to its unique stereochemical properties, (R)-Oxiran-2-ylmethanol can serve as a key intermediate in the preparation of various pharmaceuticals, agrochemicals, and fine chemicals. Its reactivity allows for selective functionalization, enabling the formation of complex molecular structures with high efficiency. In asymmetric synthesis, (R)-Oxiran-2-ylmethanol can act as a valuable chiral auxiliary, facilitating the creation of enantiomerically enriched compounds. Additionally, its compatibility with a wide range of reactions makes it a valuable tool for the construction of diverse organic molecules with specific stereochemical arrangements.

Literature

• Total synthesis of (+)-intricarene using a biogenetically patterned pathway from (-)-bipinnatin J, involving a novel transannular [5+2] (1,3-dipolar) cycloaddition.

  Organic & biomolecular chemistry 20091107

• Synthesis of novel ketoconazole derivatives as inhibitors of the human Pregnane X Receptor (PXR; NR1I2; also termed SXR, PAR).

  Bioorganic & medicinal chemistry letters 20080715

• Characterization of a novel enantioselective halohydrin hydrogen-halide-lyase.

  Applied and environmental microbiology 19940401

• Resolution and some properties of enzymes involved in enantioselective transformation of 1,3-dichloro-2-propanol to (R)-3-chloro-1,2-propanediol by Corynebacterium sp. strain N-1074.

  Journal of bacteriology 19921201