571203-78-6 | Erastin

Packsize	Purity	Availability	Price	Discounted Price
1mg	98%	in stock	$45.00	$32.00
5mg	98%	in stock	$103.00	$73.00
50mg	98%	in stock	$908.00	$636.00

Description

• Catalog Number: AB73382
• Chemical Name: Erastin
• CAS Number: 571203-78-6
• Molecular Formula: C30H31ClN4O4
• Molecular Weight: 547.0445399999999
• MDL Number: MFCD09837984
• SMILES: CCOc1ccccc1n1c(nc2c(c1=O)cccc2)C(N1CCN(CC1)C(=O)COc1ccc(cc1)Cl)C

Computed Properties

• Complexity: 871
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 39
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 8
• Undefined Atom Stereocenter Count: 1
• XLogP3: 4.8

Literature

• RSL3 and Erastin differentially regulate redox signaling to promote Smac mimetic-induced cell death.

  Oncotarget 20160927

• Ferroptosis: an iron-dependent form of nonapoptotic cell death.

  Cell 20120525

• Functional model of metabolite gating by human voltage-dependent anion channel 2.

  Biochemistry 20110503

• Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells.

  Cancer cell 20030301