57469-77-9 | Ibuprofen Lysine

Packsize	Purity	Availability	Price	Discounted Price
25mg	98%	in stock	$292.00	$205.00
100mg	98%	in stock	$795.00	$557.00
250mg	98%	in stock	$1,726.00	$1,208.00
1g	98%	in stock	$6,077.00	$4,254.00
5g	98%	in stock	$27,171.00	$19,020.00

Description

• Catalog Number: AV19863
• Chemical Name: Ibuprofen Lysine
• CAS Number: 57469-77-9
• Molecular Formula: C19H32N2O4
• Molecular Weight: 352.4684
• MDL Number: MFCD01716155
• SMILES: CC(Cc1ccc(cc1)C(C(=O)O)C)C.NCCCC[C@@H](C(=O)O)N

Computed Properties

• Complexity: 309
• Covalently-Bonded Unit Count: 2
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 25
• Hydrogen Bond Acceptor Count: 6
• Hydrogen Bond Donor Count: 4
• Rotatable Bond Count: 9
• Undefined Atom Stereocenter Count: 1

Literature

• Severe pulmonary hypertension with therapeutic L-lysine ibuprofen in 2 preterm neonates.

  Pediatrics 20120501

• Ibuprofen lysinate and sodium ibuprofen for prophylaxis of patent ductus arteriosus in preterm neonates.

  Indian pediatrics 20120101

• Effect of ibuprofen on bilirubin-albumin binding affinity in premature infants.

  Journal of perinatal medicine 20110101

• A randomized, double-blind, placebo-controlled trial on intravenous ibuprofen L-lysine for the early closure of nonsymptomatic patent ductus arteriosus within 72 hours of birth in extremely low-birth-weight infants.

  American journal of perinatology 20090301

• An optimized ibuprofen dosing scheme for preterm neonates with patent ductus arteriosus, based on a population pharmacokinetic and pharmacodynamic study.

  British journal of clinical pharmacology 20080501

• Treatment of patent ductus arteriosus: indomethacin or ibuprofen?

  Journal of perinatology : official journal of the California Perinatal Association 20080501

• Effect of ibuprofen L-lysinate on bilirubin binding to albumin as measured by saturation index and horseradish peroxidase assays.

  Journal of perinatology : official journal of the California Perinatal Association 20080401

• Nonselective cyclo-oxygenase inhibitors and glomerular filtration rate in preterm neonates.

  Pediatric nephrology (Berlin, Germany) 20051101

• Ibuprofen extrudate, a novel, rapidly dissolving ibuprofen formulation: relative bioavailability compared to ibuprofen lysinate and regular ibuprofen, and food effect on all formulations.

  Journal of clinical pharmacology 20050901

• Effect of lactic acid and iontophoresis on drug permeation across rabbit ear skin.

  International journal of pharmaceutics 20050323

• Stability of ibuprofen in injection solutions.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20050315

• Prophylactic ibuprofen in premature infants: a multicentre, randomised, double-blind, placebo-controlled trial.

  Lancet (London, England) 20041101

• Comparison of different ibuprofen-amino acid compounds with respect to emulsifying and cytotoxic properties.

  International journal of pharmaceutics 20040415

• Post-iontophoresis transport of ibuprofen lysine across rabbit ear skin.

  International journal of pharmaceutics 20031106

• Effect of a single dose of ibuprofen lysinate before embryo transfer on pregnancy rates in cows.

  Reproduction (Cambridge, England) 20010101