575-44-0 | 1,6-Dihydroxynaphthalene

Packsize	Purity	Availability	Price	Discounted Price
10g	97%	in stock	$9.00	$6.00
25g	97%	in stock	$13.00	$9.00
100g	97%	in stock	$38.00	$27.00

Description

• Catalog Number: AB57595
• Chemical Name: 1,6-Dihydroxynaphthalene
• CAS Number: 575-44-0
• Molecular Formula: C10H8O2
• Molecular Weight: 160.1693
• MDL Number: MFCD00003981
• SMILES: Oc1ccc2c(c1)cccc2O
• NSC Number: 7201

Computed Properties

• Complexity: 158
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 12
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 2
• XLogP3: 1.9

Upstream Synthesis Route

1,6-Naphthalenediol, also known as 1,6-dihydroxynaphthalene, plays a crucial role in chemical synthesis as a versatile building block and reagent. This compound is widely utilized in the production of various organic substances due to its unique chemical properties. One of the primary applications of 1,6-naphthalenediol is in the synthesis of dyes and pigments. It serves as a key intermediate in the manufacturing process of vibrant colorants used in textiles, paints, and other applications. Additionally, 1,6-naphthalenediol is employed in the synthesis of pharmaceutical compounds, where it acts as a precursor in the creation of biologically active molecules. Its hydroxyl groups enable functionalization reactions, allowing for the modification of its chemical structure to tailor properties for specific applications. Moreover, 1,6-naphthalenediol is utilized in the preparation of polymeric materials, including resins and coatings, contributing to the development of advanced materials with tailored properties. Overall, the significance of 1,6-naphthalenediol in chemical synthesis lies in its versatility and applicability across diverse industries, making it a valuable compound for innovation and product development.

Literature

• [Simultaneous determination of seven naphthalenediols in cosmetics by reversed-phase high performance liquid chromatography].

  Se pu = Chinese journal of chromatography 20120601

• Various aspects of piscine toxicology.

  Interdisciplinary toxicology 20100901

• Chemoenzymatic syntheses of prenylated aromatic small molecules using Streptomyces prenyltransferases with relaxed substrate specificities.

  Bioorganic & medicinal chemistry 20080901

• Naphthalene-1,6-diol: a three-dimensional framework built from O-H...O, O-H...pi and C-H...O hydrogen bonds.

  Acta crystallographica. Section C, Crystal structure communications 20070701

• Understanding the substrate selectivity and the product regioselectivity of Orf2-catalyzed aromatic prenylations.

  Biochemistry 20070206

• Selective antiproliferative activity of hydroxynaphthyl-beta-D-xylosides.

  Journal of medicinal chemistry 20060323

• Structural basis for the promiscuous biosynthetic prenylation of aromatic natural products.

  Nature 20050616

• Synthesis and photophysical properties of new fluorinated benzo[c]xanthene dyes as intracellular pH indicators.

  Bioorganic & medicinal chemistry letters 20011119