576-19-2 | Biocytin

Packsize	Purity	Availability	Price	Discounted Price
10mg	98%	in stock	$48.00	$34.00
25mg	98%	in stock	$93.00	$65.00
50mg	98%	in stock	$126.00	$89.00
100mg	98%	in stock	$129.00	$90.00
250mg	98%	in stock	$189.00	$132.00
1g	98%	in stock	$541.00	$379.00
5g	98%	in stock	$2,126.00	$1,489.00

Description

• Catalog Number: AI52903
• Chemical Name: Biocytin
• CAS Number: 576-19-2
• Molecular Formula: C16H28N4O4S
• Molecular Weight: 372.4829
• MDL Number: MFCD00077319
• SMILES: O=C(NCCCC[C@@H](C(=O)O)N)CCCC[C@@H]1SC[C@H]2[C@@H]1NC(=O)N2

Computed Properties

• Complexity: 491
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 4
• Heavy Atom Count: 25
• Hydrogen Bond Acceptor Count: 6
• Hydrogen Bond Donor Count: 5
• Rotatable Bond Count: 11
• XLogP3: -2.4

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• Selective serotonergic excitation of callosal projection neurons.

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• Optic neuritis in a child with biotinidase deficiency: case report and literature review.

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• Multi-level communication of human retinal pigment epithelial cells via tunneling nanotubes.

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• Neurons derived from human embryonic stem cells extend long-distance axonal projections through growth along host white matter tracts after intra-cerebral transplantation.

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• Synaptic structure and function in the mouse somatosensory cortex during chronic pain: in vivo two-photon imaging.

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• GABA metabolism and transport: effects on synaptic efficacy.

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• Enhanced hippocampal long-term potentiation and fear memory in Btbd9 mutant mice.

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• Spike-timing precision and neuronal synchrony are enhanced by an interaction between synaptic inhibition and membrane oscillations in the amygdala.

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• Adult mouse basal forebrain harbors two distinct cholinergic populations defined by their electrophysiology.

  Frontiers in behavioral neuroscience 20120101

• Are there three subdivisions in the primate subthalamic nucleus?

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• Effect of temperature on spiking patterns of neocortical layer 2/3 and layer 6 pyramidal neurons.

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• Cortical nNOS neurons co-express the NK1 receptor and are depolarized by Substance P in multiple mammalian species.

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• Genetic labeling of neuronal subsets through enhancer trapping in mice.

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  Neuroscience 20111124

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  Journal of computational neuroscience 20111101

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  Brain structure & function 20111101

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  Nature neuroscience 20111101

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  The European journal of neuroscience 20111101

• Biocytin-derived MRI contrast agent for longitudinal brain connectivity studies.

  ACS chemical neuroscience 20111019

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  The Journal of physiology 20111015

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  Nature medicine 20111001

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  Arthritis and rheumatism 20110901

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  Nature neuroscience 20110901

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  PLoS computational biology 20110901

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  Cerebral cortex (New York, N.Y. : 1991) 20110801

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  The Journal of comparative neurology 20110801

• Distinct cellular properties of identified dopaminergic and GABAergic neurons in the mouse ventral tegmental area.

  The Journal of physiology 20110801

• Effective stimuli for constructing reliable neuron models.

  PLoS computational biology 20110801

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  Nature neuroscience 20110701

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  Endocrinology 20110501

• How structure determines correlations in neuronal networks.

  PLoS computational biology 20110501

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  Seizure 20110401

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  Brain research 20110210

• The presynaptic component of the serotonergic system is required for clozapine's efficacy.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20110201

• Development and characterization of a mouse with profound biotinidase deficiency: a biotin-responsive neurocutaneous disorder.

  Molecular genetics and metabolism 20110201

• Organization of GABAergic inhibition in the motor output layer of the superior colliculus.

  The European journal of neuroscience 20110201

• Unperturbed islet α-cell function examined in mouse pancreas tissue slices.

  The Journal of physiology 20110115

• Biocytin-labelling and its impact on late 20th century studies of cortical circuitry.

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• Emergence of physiological oscillation frequencies in a computer model of neocortex.

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• Functional refinement in the projection from ventral cochlear nucleus to lateral superior olive precedes hearing onset in rat.

  PloS one 20110101

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  Frontiers in systems neuroscience 20110101

• Role of Striatum in the Pause and Burst Generation in the Globus Pallidus of 6-OHDA-Treated Rats.

  Frontiers in systems neuroscience 20110101

• The Subthalamic Nucleus becomes a Generator of Bursts in the Dopamine-Depleted State. Its High Frequency Stimulation Dramatically Weakens Transmission to the Globus Pallidus.

  Frontiers in systems neuroscience 20110101

• Explicit-duration hidden Markov model inference of UP-DOWN states from continuous signals.

  PloS one 20110101

• Visual experience modulates spatio-temporal dynamics of circuit activation.

  Frontiers in cellular neuroscience 20110101

• The corticostriatal system in dissociated cell culture.

  Frontiers in systems neuroscience 20110101

• Layer-Dependent Attentional Processing by Top-down Signals in a Visual Cortical Microcircuit Model.

  Frontiers in computational neuroscience 20110101

• Striatal fast-spiking interneurons: from firing patterns to postsynaptic impact.

  Frontiers in systems neuroscience 20110101

• Synaptic responses evoked by tactile stimuli in Purkinje cells in mouse cerebellar cortex Crus II in vivo.

  PloS one 20110101

• GenNet: A Platform for Hybrid Network Experiments.

  Frontiers in neuroinformatics 20110101

• Phenobarbital but Not Diazepam Reduces AMPA/kainate Receptor Mediated Currents and Exerts Opposite Actions on Initial Seizures in the Neonatal Rat Hippocampus.

  Frontiers in cellular neuroscience 20110101

• Wiring of divergent networks in the central auditory system.

  Frontiers in neuroanatomy 20110101

• Diffuse and specific tectopulvinar terminals in the tree shrew: synapses, synapsins, and synaptic potentials.

  PloS one 20110101

• Neurogenin2 regulates the initial axon guidance of cortical pyramidal neurons projecting medially to the corpus callosum.

  Neural development 20110101

• The corticostriatal and corticosubthalamic pathways: two entries, one target. So what?

  Frontiers in systems neuroscience 20110101

• Evidence for an auditory fovea in the New Zealand kiwi (Apteryx mantelli).

  PloS one 20110101

• Spiking patterns and their functional implications in the antennal lobe of the tobacco hornworm Manduca sexta.

  PloS one 20110101

• Parallel optical control of spatiotemporal neuronal spike activity using high-speed digital light processing.

  Frontiers in systems neuroscience 20110101

• Embryonic amygdalar transplants in adult rats with motor cortex lesions: a molecular and electrophysiological analysis.

  Frontiers in neurology 20110101

• Ripples make waves: binding structured activity and plasticity in hippocampal networks.

  Neural plasticity 20110101

• Local connections of layer 5 GABAergic interneurons to corticospinal neurons.

  Frontiers in neural circuits 20110101

• Thalamic Gap Junctions Control Local Neuronal Synchrony and Influence Macroscopic Oscillation Amplitude during EEG Alpha Rhythms.

  Frontiers in psychology 20110101

• Identification of a protein with antioxidant activity that is important for the protection against beer ageing.

  International journal of molecular sciences 20110101

• Temporal processing of vibratory communication signals at the level of ascending interneurons in Nezara viridula (Hemiptera: Pentatomidae).

  PloS one 20110101

• CD200-CD200R dysfunction exacerbates microglial activation and dopaminergic neurodegeneration in a rat model of Parkinson's disease.

  Journal of neuroinflammation 20110101

• Anatomical pathways involved in generating and sensing rhythmic whisker movements.

  Frontiers in integrative neuroscience 20110101

• Cholinergic partition cells and lamina x neurons induce a muscarinic-dependent short-term potentiation of commissural glutamatergic inputs in lumbar motoneurons.

  Frontiers in neural circuits 20110101

• Endocannabinoid Release Modulates Electrical Coupling between CCK Cells Connected via Chemical and Electrical Synapses in CA1.

  Frontiers in neural circuits 20110101

• In vivo Labeling of Constellations of Functionally Identified Neurons for Targeted in vitro Recordings.

  Frontiers in neural circuits 20110101

• Precise spatiotemporal control of optogenetic activation using an acousto-optic device.

  PloS one 20110101

• The nestin-expressing and non-expressing neurons in rat basal forebrain display different electrophysiological properties and project to hippocampus.

  BMC neuroscience 20110101

• Cognitive consilience: primate non-primary neuroanatomical circuits underlying cognition.

  Frontiers in neuroanatomy 20110101

• On the estimation of population-specific synaptic currents from laminar multielectrode recordings.

  Frontiers in neuroinformatics 20110101

• Asymmetrical interhemispheric connections develop in cat visual cortex after early unilateral convergent strabismus: anatomy, physiology, and mechanisms.

  Frontiers in neuroanatomy 20110101

• Multiscale exploration of mouse brain microstructures using the knife-edge scanning microscope brain atlas.

  Frontiers in neuroinformatics 20110101

• Statistical structure of lateral connections in the primary visual cortex.

  Neural systems & circuits 20110101

• Dynamic development of the first synapse impinging on adult-born neurons in the olfactory bulb circuit.

  Neural systems & circuits 20110101

• Population diversity and function of hyperpolarization-activated current in olfactory bulb mitral cells.

  Scientific reports 20110101

• Conserved properties of dendritic trees in four cortical interneuron subtypes.

  Scientific reports 20110101

• Predicted contextual modulation varies with distance from pinwheel centers in the orientation preference map.

  Scientific reports 20110101

• Visual receptive field properties of neurons in the superficial superior colliculus of the mouse.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20101208

• Direct projections of omnipause neurons to reticulospinal neurons: a double-labeling light microscopic study in the cat.

  The Journal of comparative neurology 20101201

• Strategy for treating motor neuron diseases using a fusion protein of botulinum toxin binding domain and streptavidin for viral vector access: work in progress.

  Toxins 20101201

• Electrophysiological characteristics of cells in the anterior caudal lobe of the mormyrid cerebellum.

  Neuroscience 20101124

• 111In-DTPA-Biotin uptake by Staphylococcus aureus.

  Nuclear medicine communications 20101101

• A post-burst after depolarization is mediated by group i metabotropic glutamate receptor-dependent upregulation of Ca(v)2.3 R-type calcium channels in CA1 pyramidal neurons.

  PLoS biology 20101101

• Serotonin 3A receptor subtype as an early and protracted marker of cortical interneuron subpopulations.

  Cerebral cortex (New York, N.Y. : 1991) 20101001

• Dimensions of a projection column and architecture of VPM and POm axons in rat vibrissal cortex.

  Cerebral cortex (New York, N.Y. : 1991) 20101001

• Cell type-specific thalamic innervation in a column of rat vibrissal cortex.

  Cerebral cortex (New York, N.Y. : 1991) 20101001

• Excitatory input onto hilar somatostatin interneurons is increased in a chronic model of epilepsy.

  Journal of neurophysiology 20101001

• Clarke's column neurons as the focus of a corticospinal corollary circuit.

  Nature neuroscience 20101001

• Functional connectivity and selective odor responses of excitatory local interneurons in Drosophila antennal lobe.

  Neuron 20100923

• Tunable leuko-polymersomes that adhere specifically to inflammatory markers.

  Langmuir : the ACS journal of surfaces and colloids 20100907

• Rebound discharge in deep cerebellar nuclear neurons in vitro.

  Cerebellum (London, England) 20100901

• A physiological frequency-position map of the chinchilla cochlea.

  Hearing research 20100901

• Comparative analysis of techniques to purify plasma membrane proteins.

  Journal of biomolecular techniques : JBT 20100901

• Brief bursts self-inhibit and correlate the pyramidal network.

  PLoS biology 20100901

• Rapid desynchronization of an electrically coupled interneuron network with sparse excitatory synaptic input.

  Neuron 20100812

• Distribution of dendrites from longissimus lumborum motoneurons stained intracellularly with biocytin in adult cats.

  The Journal of veterinary medical science 20100801

• Local axon collaterals of lamina I projection neurons in the spinal cord of young rats.

  The Journal of comparative neurology 20100715

• Synchronization dynamics in response to plaid stimuli in monkey V1.

  Cerebral cortex (New York, N.Y. : 1991) 20100701

• Tonic modulation of GABA release by nicotinic acetylcholine receptors in layer V of the murine prefrontal cortex.

  Cerebral cortex (New York, N.Y. : 1991) 20100701

• Dopaminergic modulation of spiny neurons in the turtle striatum.

  Cellular and molecular neurobiology 20100701

• Gamma-aminobutyric acid (GABA) is an autocrine excitatory transmitter in human pancreatic beta-cells.

  Diabetes 20100701

• Oligodendrocytes in mouse corpus callosum are coupled via gap junction channels formed by connexin47 and connexin32.

  Glia 20100701

• A paired-end sequencing strategy to map the complex landscape of transcription initiation.

  Nature methods 20100701

• Sensory and cortical activation of distinct glial cell subtypes in the somatosensory thalamus of young rats.

  The European journal of neuroscience 20100701

• Activity-dependent changes in the electrophysiological properties of regular spiking neurons in the sensorimotor cortex of the rat in vitro.

  Behavioural brain research 20100619

• Granule cells in the CA3 area.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20100616

• Differences in subthreshold resonance of hippocampal pyramidal cells and interneurons: the role of h-current and passive membrane characteristics.

  The Journal of physiology 20100615

• Structural and functional changes in tau mutant mice neurons are not linked to the presence of NFTs.

  Experimental neurology 20100601

• Effect of gene dosage on single-cell hippocampal electrophysiology in a murine model of SSADH deficiency (gamma-hydroxybutyric aciduria).

  Epilepsy research 20100601

• Neurites regrowth of cortical neurons by GSK3beta inhibition independently of Nogo receptor 1.

  Journal of neurochemistry 20100601

• Distinct synaptic properties of perisomatic inhibitory cell types and their different modulation by cholinergic receptor activation in the CA3 region of the mouse hippocampus.

  The European journal of neuroscience 20100601

• Bistable, irregular firing and population oscillations in a modular attractor memory network.

  PLoS computational biology 20100601

• Electrophysiological and morphological properties of Cajal-Retzius cells with different ontogenetic origins.

  Neuroscience 20100519

• Postnatal switch from synaptic to extrasynaptic transmission between interneurons and NG2 cells.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20100519

• Electrophysiological and morphological characteristics and synaptic connectivity of tyrosine hydroxylase-expressing neurons in adult mouse striatum.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20100519

• Diverse antiepileptic drugs increase the ratio of background synaptic inhibition to excitation and decrease neuronal excitability in neurones of the rat entorhinal cortex in vitro.

  Neuroscience 20100505

• Neonatal rearing conditions distinctly shape locus coeruleus neuronal activity, dendritic arborization, and sensitivity to corticotrophin-releasing factor.

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  Neuron 20070816

• Early alterations in the electrophysiological properties of rat spinal motoneurones following neonatal axotomy.

  The Journal of physiology 20070801

• Presynaptic Inhibition of GABAA receptor-mediated unitary IPSPs by cannabinoid receptors at synapses between CCK-positive interneurons in rat hippocampus.

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  The European journal of neuroscience 20070801

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  The European journal of neuroscience 20070801

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  The Journal of neuroscience : the official journal of the Society for Neuroscience 20070704

• Reduced axon sprouting after treatment that diminishes microglia accumulation at lesions in the leech CNS.

  The Journal of comparative neurology 20070701

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  Brain structure & function 20070701

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  Brain structure & function 20070701

• Anatomy of the posterior caudal lobe of the cerebellum and the eminentia granularis posterior in a mormyrid fish.

  The Journal of comparative neurology 20070610

• Cyclic AMP signaling contributes to neural plasticity and hyperexcitability in AH sensory neurons following intestinal Trichinella spiralis-induced inflammation.

  International journal for parasitology 20070601

• Cytomegalic interneurons: a new abnormal cell type in severe pediatric cortical dysplasia.

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• Calculations of apparent ruminal synthesis and intestinal absorption of biotin in dairy cows as influenced by the extraction method.

  Archives of animal nutrition 20070601

• Olfactory information converges in the amygdaloid cortex via the piriform and entorhinal cortices: observations in the guinea pig isolated whole-brain preparation.

  The European journal of neuroscience 20070601

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  Neuroscience 20070525

• Layer- and cell-type-specific suprathreshold stimulus representation in rat primary somatosensory cortex.

  The Journal of physiology 20070515

• Cytological organization of the central gelatinosa in the turtle spinal cord.

  The Journal of comparative neurology 20070510

• Protein-resistant self-assembled monolayers on gold with latent aldehyde functions.

  Langmuir : the ACS journal of surfaces and colloids 20070508

• P/Q-type, but not N-type, calcium channels mediate GABA release from fast-spiking interneurons to pyramidal cells in rat prefrontal cortex.

  Journal of neurophysiology 20070501

• Otolith fibers and terminals in chick vestibular nuclei.

  The Journal of comparative neurology 20070501

• Efferent connections of the ventral auditory area in the rat cortex: implications for auditory processing related to emotion.

  The European journal of neuroscience 20070501

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  The European journal of neuroscience 20070501

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  Biophysical journal 20070415

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  Neuron 20070405

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  The Journal of physiology 20070401

• A locally produced nutritional supplement in community-based HIV and AIDS patients.

  International journal of palliative nursing 20070401

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  Neuroscience 20070302

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  The Journal of physiology 20070301

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• Morphological and physiological properties of parvalbumin- and calretinin-containing gamma-aminobutyric acidergic neurons in the substantia nigra.

  The Journal of comparative neurology 20070210

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  Brain research bulletin 20070109

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  BMC neuroscience 20070101

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  Journal of biomedical optics 20070101

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  Frontiers in neural circuits 20070101

• Output of neurogliaform cells to various neuron types in the human and rat cerebral cortex.

  Frontiers in neural circuits 20070101

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  Frontiers in neural circuits 20070101

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  Frontiers in neuroanatomy 20070101

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  The Journal of comparative neurology 20061220

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• Bioactive hydrogel substrates: probing leukocyte receptor-ligand interactions in parallel plate flow chamber studies.

  Annals of biomedical engineering 20061101

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  Neuroscience 20061027

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  Journal of neurophysiology 20061001

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  Arteriosclerosis, thrombosis, and vascular biology 20061001

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  Current eye research 20061001

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  Neuroscience 20060901

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  The Journal of comparative neurology 20060901

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  The European journal of neuroscience 20060901

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  Neuroscience 20060825

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  Neuroscience 20060811

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  Endocrinology 20060801

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  The Journal of comparative neurology 20060720

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  Analytical biochemistry 20060701

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  Neuroscience 20060630

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  PLoS biology 20060601

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  The Journal of neuroscience : the official journal of the Society for Neuroscience 20060503

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  Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology 20060501

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  Biological cybernetics 20060401

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  Cerebral cortex (New York, N.Y. : 1991) 20060301

• Isolation rearing or methamphetamine traumatisation induce a 'dysconnection' of prefrontal efferents in gerbils: implications for schizophrenia.

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  Endocrinology 20060301

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  Acta physiologica Hungarica 20060301

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  Cerebral cortex (New York, N.Y. : 1991) 20060201

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  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20060201

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  The Journal of comparative neurology 20060110

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  The European journal of neuroscience 20060101

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  Neuroscience 20060101

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  Molecular pain 20060101

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  Hippocampus 20060101

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  Molecular pharmaceutics 20060101

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  The Journal of neuroscience : the official journal of the Society for Neuroscience 20051005

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  The European journal of neuroscience 20051001

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  Brain research bulletin 20050915

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  The Journal of physiology 20050901

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  The Journal of comparative neurology 20050801

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  Circulation research 20050708

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• Electrophysiological properties of neurons in the basal ganglia of the domestic chick: conservation and divergence in the evolution of the avian basal ganglia.

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  The European journal of neuroscience 20050701

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  Nature neuroscience 20050601

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  Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20050601

• Differential modulation of anterior cingulate cortical activity by afferents from ventral tegmental area and mediodorsal thalamus.

  The European journal of neuroscience 20050601

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  The European journal of neuroscience 20050601

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  Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20050529

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  The Journal of neuroscience : the official journal of the Society for Neuroscience 20050413

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• Optical current source density analysis in hippocampal organotypic culture shows that spreading depression occurs with uniquely reversing currents.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20050413

• Increased action potential firing rates of layer 2/3 pyramidal cells in the prefrontal cortex are significantly related to cognitive performance in aged monkeys.

  Cerebral cortex (New York, N.Y. : 1991) 20050401

• Monosynaptic connections between pairs of spiny stellate cells in layer 4 and pyramidal cells in layer 5A indicate that lemniscal and paralemniscal afferent pathways converge in the infragranular somatosensory cortex.

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  The Journal of comparative neurology 20050321

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• Developmental changes in spinal motoneuron dendrites in neonatal mice.

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  Experimental brain research 20050301

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  Endocrinology 20050301

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  Nature neuroscience 20050201

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  Nature neuroscience 20050201

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  International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20050201

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• Expression of type 1 corticotropin-releasing factor receptor in the guinea pig enteric nervous system.

  The Journal of comparative neurology 20050117

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  Neuroscience 20050101

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  Brain, behavior and evolution 20050101

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  Methods in molecular biology (Clifton, N.J.) 20050101

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  Neuroscience 20050101

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  Neuroscience 20050101

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  Molecular pain 20050101

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  Neuroscience 20050101

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  Epilepsia 20050101

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  Neuroscience 20050101

• Evolutionary conservation of biotinidase: implications for the enzyme's structure and subcellular localization.

  Molecular genetics and metabolism 20050101

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  Neuroscience 20050101

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  Neuroscience 20050101

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• Transgenic mice expressing a fluorescent in vivo label in a distinct subpopulation of neocortical layer 5 pyramidal cells.

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  The European journal of neuroscience 20041101

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  The European journal of neuroscience 20041101

• The role of the electrophysiological properties of neurons in the mechanisms grouping their discharges in the cerebral cortex.

  Neuroscience and behavioral physiology 20041101

• Cortical GABA interneurons in neurovascular coupling: relays for subcortical vasoactive pathways.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20041013

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  The Journal of comparative neurology 20041004

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  Synapse (New York, N.Y.) 20041001

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  Glia 20041001

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  The European journal of neuroscience 20041001

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  Neuroscience letters 20040909

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  The European journal of neuroscience 20040801

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  Nature neuroscience 20040801

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  Journal of the American Chemical Society 20040714

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  Langmuir : the ACS journal of surfaces and colloids 20040622

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  Cerebral cortex (New York, N.Y. : 1991) 20040601

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• The anterograde and retrograde axonal transport of biotinylated dextran amine and biocytin in the nervous system of teleosts.

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  Journal of the Association for Research in Otolaryngology : JARO 20040601

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  The European journal of neuroscience 20040501

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  Archives italiennes de biologie 20040501

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  The Journal of neuroscience : the official journal of the Society for Neuroscience 20040211

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  Experimental neurology 20040201

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  The European journal of neuroscience 20040201

• Morphological and physiological features of a set of spinal substantia gelatinosa neurons defined by green fluorescent protein expression.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20040128

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  The Journal of comparative neurology 20040106

• Correlation of electrophysiological and morphological characteristics of enteric neurons in the mouse colon.

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  Neuroscience 20040101

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  The Journal of neuroscience : the official journal of the Society for Neuroscience 20031203

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  The Journal of physiology 20021101

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  The Journal of comparative neurology 20021021

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  The Journal of comparative neurology 20020909

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  Cerebral cortex (New York, N.Y. : 1991) 20020901

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  Anatomy and embryology 20020701

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  Cerebral cortex (New York, N.Y. : 1991) 20020401

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  The European journal of neuroscience 20011001

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  Clinica chimica acta; international journal of clinical chemistry 20010401

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  Journal of neurophysiology 20010201

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• Disinhibition in rat superior colliculus mediated by GABAc receptors.

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  The European journal of neuroscience 20010101

• Properties of entorhinal cortex deep layer neurons projecting to the rat dentate gyrus.

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• Hepatic nucleases. Extrahepatic origin and association of neutral liver ribonuclease with lysosomes.

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