578-74-5 | Apigenin 7-Glucoside

Packsize	Purity	Availability	Price	Discounted Price
1mg	99%	in stock	$28.00	$19.00
5mg	99%	in stock	$62.00	$43.00
10mg	99%	in stock	$93.00	$65.00

Description

• Catalog Number: AB70771
• Chemical Name: Apigenin 7-Glucoside
• CAS Number: 578-74-5
• Molecular Formula: C21H20O10
• Molecular Weight: 432.3775
• MDL Number: MFCD00016787
• SMILES: OC[C@H]1O[C@@H](Oc2cc(O)c3c(c2)oc(cc3=O)c2ccc(cc2)O)[C@@H]([C@H]([C@@H]1O)O)O

Computed Properties

• Complexity: 675
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 5
• Heavy Atom Count: 31
• Hydrogen Bond Acceptor Count: 10
• Hydrogen Bond Donor Count: 6
• Rotatable Bond Count: 4
• XLogP3: -0.1

Literature

• Analysis of the erythroid differentiation effect of flavonoid apigenin on K562 human chronic leukemia cells.

  Chemico-biological interactions 20140905

• A new antifungal and cytotoxic C-methylated flavone glycoside from Picea neoveitchii.

  Bioorganic & medicinal chemistry letters 20120915

• LC determination of luteolin-7-O-β-D-glucoside and apigenin-7-O-β-D-glucoside in rat plasma after administration of Humulus scandens extract and its application to pharmacokinetic studies.

  Natural product research 20120101

• Identification of estrogen receptor dimer selective ligands reveals growth-inhibitory effects on cells that co-express ERα and ERβ.

  PloS one 20120101

• Screening medicinal plants for the detection of novel antimalarial products applying the inhibition of β-hematin formation.

  Journal of pharmaceutical and biomedical analysis 20111215

• Generation of stable reporter breast cancer cell lines for the identification of ER subtype selective ligands.

  Biochemical pharmacology 20111215

• Antioxidant and antigenotoxic properties of compounds isolated from Marrubium deserti de Noé.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20111201

• [Study on the flavanone constitutes of Buddleja davidii].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20111001

• [Simultaneous determination of 6 active components in Chrysanthemum morifolium by HPLC].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110601

• Hexaconazole induces antioxidant protection and apigenin-7-glucoside accumulation in Matricaria chamomilla plants subjected to drought stress.

  Journal of plant physiology 20110515

• Apigetrin induces erythroid differentiation of human leukemia cells K562: proteomics approach.

  Molecular nutrition & food research 20110501

• High-performance liquid chromatographic determination and pharmacokinetic study of apigenin-7-O-β-D-glucoside in rat plasma after intravenous administration.

  Archives of pharmacal research 20110501

• Flavonoid composition of Juniperus oblonga Bieb.

  Bulletin of experimental biology and medicine 20110401

• Structure-activity relationships of flavonoids as inhibitors of breast cancer resistance protein (BCRP).

  Bioorganic & medicinal chemistry 20110315

• Phenolic compounds from Achillea millefolium L. and their bioactivity.

  Acta biochimica Polonica 20110101

• Isolation of 3 flavonoids from Mentha longifolia (L.) Hudson subsp. longifolia and determination of their genotoxic potentials by using the E. coli WP2 test system.

  Journal of food science 20110101

• Flavonoids from Dracocephalum tanguticum and their cardioprotective effects against doxorubicin-induced toxicity in H9c2 cells.

  Bioorganic & medicinal chemistry letters 20101115

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• Multivariate QSAR study on the antimutagenic activity of flavonoids against 3-NFA on Salmonella typhimurium TA98.

  European journal of medicinal chemistry 20101001

• Secondary metabolites of Hypericum confertum and their possible chemotaxonomic significance.

  Natural product communications 20100601

• [Chemical constituents of Discocleidion rufescens].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100601

• [Chemical constituents from Lagotis brevituba].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100401

• Reliability of bond dissociation enthalpy calculated by the PM6 method and experimental TEAC values in antiradical QSAR of flavonoids.

  Bioorganic & medicinal chemistry 20100101

• [Study on the flavonoids constituents of Trachelospermum jasminoides].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20100101

• [Chemical constituents in Buddleja albiflora].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20091201

• Antiestrogenic constituents of the Thai medicinal plants Capparis flavicans and Vitex glabrata.

  Journal of natural products 20091101

• Mesophyll distribution of 'antioxidant' flavonoid glycosides in Ligustrum vulgare leaves under contrasting sunlight irradiance.

  Annals of botany 20091001

• Neuraminidase inhibitory activities of flavonols isolated from Rhodiola rosea roots and their in vitro anti-influenza viral activities.

  Bioorganic & medicinal chemistry 20091001

• Triterpenoids and flavonoids from celery (Apium graveolens).

  Journal of natural products 20090901

• [Studies on antibacterial constituents of Discocleidion rufescens (2)].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090601

• [Studies on chemical components of Lobelia chinensis].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090201

• A new acylated quercetin glycoside from the leaves of Stevia rebaudiana Bertoni.

  Natural product research 20090101

• Simultaneous determination of nine major active compounds in Dracocephalum rupestre by HPLC.

  Journal of pharmaceutical and biomedical analysis 20081215

• Chemical constituents from the seeds of Trifolium alexandrinum.

  Natural product research 20081201

• [Flavones from flowers of Paulownia fortunei].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20081101

• Solid-liquid transfer of biophenols from olive leaves for the enrichment of edible oils by a dynamic ultrasound-assisted approach.

  Journal of agricultural and food chemistry 20080827

• [Studies on chemical constituents from Pteris multifida].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20080801

• Antioxidative activity of the flower of Torenia fournieri.

  Journal of natural medicines 20080401

• [Studies on chemical constituents in Huangjuhua (flowers of Chrysanthemum morifolium)].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080301

• Chemical constituents from the leaves of Broussonetia papyrifera.

  Yao xue xue bao = Acta pharmaceutica Sinica 20080201

• Antiproliferative and apoptotic effects of chamomile extract in various human cancer cells.

  Journal of agricultural and food chemistry 20071114

• Two new phenolic constituents of Humulus japonicus and their cytotoxicity test in vitro.

  Archives of pharmacal research 20071101

• Achillea millefolium L. s.l. -- is the anti-inflammatory activity mediated by protease inhibition?

  Journal of ethnopharmacology 20070905

• Constituents of Ocimum sanctum with antistress activity.

  Journal of natural products 20070901

• [Studies on flavones in of Lavandula augustifolia].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070501

• In vitro estrogenic activity of Achillea millefolium L.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20070201

• Superheated liquid extraction of oleuropein and related biophenols from olive leaves.

  Journal of chromatography. A 20061215

• [Determination of main flavone glycosides in Flos Chrysanthemi and observation of factors influenced contents].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20061101

• [Studies on chemical constituents of Acroptilon repens].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20061101

• Development of an HPLC-PAD-MS assay for the identification and quantification of major phenolic edelweiss (Leontopodium alpium Cass.) constituents.

  Phytochemical analysis : PCA 20060101

• Effects of compounds in leaves of Salix matsudana on arachidonic acid metabolism.

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20051201

• Additional antiprotozoal constituents from Cuphea pinetorum, a plant used in Mayan traditional medicine to treat diarrhoea.

  Phytotherapy research : PTR 20050801

• Mechanisms of apigenin-7-glucoside as a hepatoprotective agent.

  Biomedical and environmental sciences : BES 20050201

• Phenolic compounds from the leaf extract of artichoke (Cynara scolymus L.) and their antimicrobial activities.

  Journal of agricultural and food chemistry 20041201

• [Studies on the flavonoids in herb from Scutellaria barbata].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20041001

• Antioxidants and inhibitor of matrix metalloproteinase-1 expression from leaves of Zostera marina L.

  Archives of pharmacal research 20040201

• Supercritical carbon dioxide extraction of chamomile flowers: extraction efficiency, stability, and in-line inclusion of chamomile-carbon dioxide extract in beta-cyclodextrin.

  Phytochemical analysis : PCA 20040101

• Protective effect of flavonoids against aging- and lipopolysaccharide-induced cognitive impairment in mice.

  Pharmacology 20031001

• Antioxidative glycosides from the leaves of Ligustrum robustum.

  Journal of natural products 20030601

• Calmodulin inhibitors from Leucophyllum ambiguum.

  Journal of natural products 20030201

• Simultaneous determination of seven compounds in snow lotus herb using high-performance liquid chromatography.

  Journal of chromatographic science 20030101

• A novel cytotoxic C-methylated biflavone, taiwanhomoflavone-B from the twigs of Cephalotaxus wilsoniana.

  Chemical & pharmaceutical bulletin 20021201

• Absorption and metabolism of flavonoids in the caco-2 cell culture model and a perused rat intestinal model.

  Drug metabolism and disposition: the biological fate of chemicals 20020401

• Phenolic glycosides from Phagnalon rupestre.

  Phytochemistry 20020401

• Effect of six flavonoid compounds from Ixeris sonchifolia on stimulus-induced superoxide generation and tyrosyl phosphorylation in human neutrophils.

  Clinica chimica acta; international journal of clinical chemistry 20020201

• [Studies on the chemical constituents from Chrysanthemum morifolium Ramat].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20010801

• Flavones and sesquiterpene lactones from Achillea atrata subsp. multifida: antimicrobial activity.

  Journal of natural products 19990601

• Anti-AIDS agents, 10. Acacetin-7-O-beta-D-galactopyranoside, an anti-HIV principle from Chrysanthemum morifolium and a structure-activity correlation with some related flavonoids.

  Journal of natural products 19940101