58-63-9 | Inosine

Packsize	Purity	Availability	Price	Discounted Price
25g	98%	in stock	$13.00	$9.00
100g	98%	in stock	$26.00	$18.00
5kg	98%	in stock	$1,038.00	$727.00
10kg	98%	in stock	$1,966.00	$1,377.00

Description

• Catalog Number: AB46284
• Chemical Name: Inosine
• CAS Number: 58-63-9
• Molecular Formula: C10H12N4O5
• Molecular Weight: 268.2261
• MDL Number: MFCD00066770
• SMILES: OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1[nH]cnc2=O

Computed Properties

• Complexity: 405
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 4
• Heavy Atom Count: 19
• Hydrogen Bond Acceptor Count: 7
• Hydrogen Bond Donor Count: 4
• Rotatable Bond Count: 2
• XLogP3: -1.3

Literature

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• Chemical fingerprint analysis of Fritillaria delavayi Franch. by high-performance liquid chromatography.

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• Mycophenolate mofetil and daclizumab targeting T lymphocytes in bleomycin-induced experimental scleroderma.

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• Synthesis of 2'-substituted inosine analogs via unusual masking of the 6-hydroxyl group.

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• Genes adopt non-optimal codon usage to generate cell cycle-dependent oscillations in protein levels.

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• Pivotal role of inosine triphosphate pyrophosphatase in maintaining genome stability and the prevention of apoptosis in human cells.

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• Metabolomic profiles of myocardial ischemia under treatment with salvianolic acid B.

  Chinese medicine 20120101

• Extracellular ATP triggers proteolysis and cytosolic Ca²⁺ rise in Plasmodium berghei and Plasmodium yoelii malaria parasites.

  Malaria journal 20120101

• Role of the gerA operon in L-alanine germination of Bacillus licheniformis spores.

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• Comparative mitochondrial proteomics: perspective in human diseases.

  Journal of hematology & oncology 20120101

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• High recovery of cell-free methylated DNA based on a rapid bisulfite-treatment protocol.

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  Enzyme research 20120101

• Dark matter RNA: an intelligent scaffold for the dynamic regulation of the nuclear information landscape.

  Frontiers in genetics 20120101

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  Frontiers in neurology 20120101

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  Frontiers in microbiology 20120101

• Time dependent neuroprotection of mycophenolate mofetil: effects on temporal dynamics in glial proliferation, apoptosis, and scar formation.

  Journal of neuroinflammation 20120101

• MELTING, a flexible platform to predict the melting temperatures of nucleic acids.

  BMC bioinformatics 20120101

• Suppression of the Nrf2-dependent antioxidant response by glucocorticoids and 11β-HSD1-mediated glucocorticoid activation in hepatic cells.

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• Naturally occurring culturable aerobic gut flora of adult Phlebotomus papatasi, vector of Leishmania major in the Old World.

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• Shifting the paradigm: the putative mitochondrial protein ABCB6 resides in the lysosomes of cells and in the plasma membrane of erythrocytes.

  PloS one 20120101

• High-throughput sequencing of 16S rRNA gene amplicons: effects of extraction procedure, primer length and annealing temperature.

  PloS one 20120101

• Extrasynaptic neurotransmission in the modulation of brain function. Focus on the striatal neuronal-glial networks.

  Frontiers in physiology 20120101

• Efficiency of purine utilization by Helicobacter pylori: roles for adenosine deaminase and a NupC homolog.

  PloS one 20120101

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• HILIC-MS/MS method for the quantitation of nucleotides in infant formula and adult nutritional formula: First Action 2011.21.

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  PloS one 20120101

• A novel computational strategy to identify A-to-I RNA editing sites by RNA-Seq data: de novo detection in human spinal cord tissue.

  PloS one 20120101

• A-to-I editing of protein coding and noncoding RNAs.

  Critical reviews in biochemistry and molecular biology 20120101

• Proteomic and systems biology analysis of monocytes exposed to securinine, a GABA(A) receptor antagonist and immune adjuvant.

  PloS one 20120101

• Research on and clinical importance of duplications in various chromosomal regions in addition to Philadelphia chromosome in chronic myeloid leukemia.

  Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20120101

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  Likars'ka sprava 20120101

• Identification of an annonaceous acetogenin mimetic, AA005, as an AMPK activator and autophagy inducer in colon cancer cells.

  PloS one 20120101

• Characterization of ectonucleotidases in human medulloblastoma cell lines: ecto-5'NT/CD73 in metastasis as potential prognostic factor.

  PloS one 20120101

• Electron donor-acceptor interactions with flanking purines influence the efficiency of thymine photodimerization.

  Journal of the American Chemical Society 20111228

• Visualizing adenosine-to-inosine RNA editing in the Drosophila nervous system.

  Nature methods 20111225

• Detection of endoplasmic reticulum stress markers and production enhancement treatments in transgenic goats expressing recombinant human butyrylcholinesterase.

  Transgenic research 20111201

• Molecular characterization of adenosine 5'-monophosphate deaminase--the key enzyme responsible for the umami taste of nori (Porphyra yezoensis Ueda, Rhodophyta).

  Marine biotechnology (New York, N.Y.) 20111201

• Possible biological markers of the time of processing of dry-cured ham.

  Meat science 20111201

• Distinct fluctuations in nucleotide metabolism accompany the enhanced in vitro embryogenic capacity of Brassica cells over-expressing SHOOTMERISTEMLESS.

  Planta 20111201

• Emerging role of extracellular nucleotides and adenosine in multiple sclerosis.

  Purinergic signalling 20111201

• Intracerebroventricular administration of inosine is anticonvulsant against quinolinic acid-induced seizures in mice: an effect independent of benzodiazepine and adenosine receptors.

  Pharmacology, biochemistry, and behavior 20111201

• Modulation of dADAR-dependent RNA editing by the Drosophila fragile X mental retardation protein.

  Nature neuroscience 20111201

• Inosine, not adenosine, initiates endothelial glycocalyx degradation in cardiac ischemia and hypoxia.

  Nucleosides, nucleotides & nucleic acids 20111201

• Purine nucleoside phosphorylase deficiency: a mutation update.

  Nucleosides, nucleotides & nucleic acids 20111201

• Simultaneous determination of purine and pyrimidine metabolites in HPRT-deficient cell lines.

  Nucleosides, nucleotides & nucleic acids 20111201

• Structural insights into the inhibition of cytosolic 5'-nucleotidase II (cN-II) by ribonucleoside 5'-monophosphate analogues.

  PLoS computational biology 20111201

• Promoting Bacillus cereus spore germination for subsequent inactivation by mild heat treatment.

  Journal of food protection 20111201

• The protective effects of inosine against chemical hypoxia on cultured rat oligodendrocytes.

  Cellular and molecular neurobiology 20111101

• Adenosine-to-inosine RNA editing meets cancer.

  Carcinogenesis 20111101

• Purinergic regulation of high-glucose-induced caspase-1 activation in the rat retinal Müller cell line rMC-1.

  American journal of physiology. Cell physiology 20111101

• Pyrimidine degradation influences germination seedling growth and production of Arabidopsis seeds.

  Journal of experimental botany 20111101

• Shedding of the coronary endothelial glycocalyx: effects of hypoxia/reoxygenation vs ischaemia/reperfusion.

  British journal of anaesthesia 20111101

• Structures of Burkholderia thailandensis nucleoside kinase: implications for the catalytic mechanism and nucleoside selectivity.

  Acta crystallographica. Section D, Biological crystallography 20111101

• Nucleoside optimization for RNAi: a high-throughput platform.

  Journal of the American Chemical Society 20111026

• Absence of equilibrative nucleoside transporter 1 in ENT1 knockout mice leads to altered nucleoside levels following hypoxic challenge.

  Life sciences 20111024

• Pin1 and WWP2 regulate GluR2 Q/R site RNA editing by ADAR2 with opposing effects.

  The EMBO journal 20111019

• Differential adenosine uptake in mixed neuronal/glial or purified glial cultures of avian retinal cells: modulation by adenosine metabolism and the ERK cascade.

  Biochemical and biophysical research communications 20111014

• The state-of-the-art determination of urinary nucleosides using chromatographic techniques 'hyphenated' with advanced bioinformatic methods.

  Analytical and bioanalytical chemistry 20111001

• Guanosine supplementation reduces the antiproliferative and apoptotic effects of the IMPDH inhibitor gnidilatimonoein in K562 cells.

  Cell biology international 20111001

• Solid-phase synthesis and pharmacological evaluation of novel nucleoside-tethered dinuclear platinum(II) complexes.

  Bioorganic & medicinal chemistry letters 20111001

• Competition between ADAR and RNAi pathways for an extensive class of RNA targets.

  Nature structural & molecular biology 20111001

• High admission levels of γ-glutamyltransferase predict poor myocardial perfusion after primary percutaneous intervention.

  Clinics (Sao Paulo, Brazil) 20111001

• Identification of widespread ultra-edited human RNAs.

  PLoS genetics 20111001

• Proteomic analysis of excretory-secretory products of Heligmosomoides polygyrus assessed with next-generation sequencing transcriptomic information.

  PLoS neglected tropical diseases 20111001

• Cyclophosphamide-induced disruption of umami taste functions and taste epithelium.

  Neuroscience 20110929

• Analysis of urinary nucleosides as potential tumor markers in human breast cancer by high performance liquid chromatography/electrospray ionization tandem mass spectrometry.

  Clinica chimica acta; international journal of clinical chemistry 20110918

• Nucleobase transport by human equilibrative nucleoside transporter 1 (hENT1).

  The Journal of biological chemistry 20110916

• Identification and quantification of nucleosides and nucleobases in Geosaurus and Leech by hydrophilic-interaction chromatography.

  Talanta 20110915

• Genome-wide evaluation and discovery of vertebrate A-to-I RNA editing sites.

  Biochemical and biophysical research communications 20110902

• An improved isolation procedure for adult mouse cardiomyocytes.

  Cell biochemistry and biophysics 20110901

• Speciation studies on the complex formation reactions of [Pd(N,N-diethyl-ethylendiamine)(H2O)2]2+ with some bio-relevant ligands and displacement reaction by mercaptoethylamine.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20110901

• Extracellular cAMP-adenosine pathways in the mouse kidney.

  American journal of physiology. Renal physiology 20110901

• New insights into neuromyelitis optica.

  Journal of clinical neurology (Seoul, Korea) 20110901

• Hippocampal metabolomics reveals 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity associated with ageing in Sprague-Dawley rats.

  Talanta 20110815

• A systematic review of directly applied biologic therapies for acute spinal cord injury.

  Journal of neurotrauma 20110801

• A systematic review of non-invasive pharmacologic neuroprotective treatments for acute spinal cord injury.

  Journal of neurotrauma 20110801

• De novo engineering and metabolic flux analysis of inosine biosynthesis in Bacillus subtilis.

  Biotechnology letters 20110801

• Adenosine deaminase from Streptomyces coelicolor: recombinant expression, purification and characterization.

  Protein expression and purification 20110801

• P2Y₂ receptor activation decreases blood pressure and increases renal Na⁺ excretion.

  American journal of physiology. Regulatory, integrative and comparative physiology 20110801

• Glutamate receptor RNA editing in health and disease.

  Biochemistry. Biokhimiia 20110801

• A-to-I RNA editing modulates the pharmacology of neuronal ion channels and receptors.

  Biochemistry. Biokhimiia 20110801

• Identification of A-to-I RNA editing: dotting the i's in the human transcriptome.

  Biochemistry. Biokhimiia 20110801

• High-sensitivity capillary electrophoresis method for monitoring purine nucleoside phosphorylase and adenosine deaminase reactions by a reversed electrode polarity switching mode.

  Journal of chromatography. A 20110722

• Mechanism of inhibition of Bacillus anthracis spore outgrowth by the lantibiotic nisin.

  ACS chemical biology 20110715

• Low-temperature NMR studies on inosine wobble base pairs.

  The journal of physical chemistry. B 20110707

• Rejuvenation capacity of red blood cells in additive solutions over long-term storage.

  Transfusion 20110701

• Biochemical detection of adenosine deaminase in Trypanosoma evansi.

  Experimental parasitology 20110701

• Serum and urine metabolite profiling reveals potential biomarkers of human hepatocellular carcinoma.

  Molecular & cellular proteomics : MCP 20110701

• Mesenchymal stromal cells up-regulate CD39 and increase adenosine production to suppress activated T-lymphocytes.

  Stem cell research 20110701

• Intrauterine growth restriction alters the metabonome of the serum and jejunum in piglets.

  Molecular bioSystems 20110701

• Arabidopsis thaliana nucleosidase mutants provide new insights into nucleoside degradation.

  The New phytologist 20110701

• The C-terminal end of the Trypanosoma brucei editing deaminase plays a critical role in tRNA binding.

  RNA (New York, N.Y.) 20110701

• Complete genome sequence of Treponema succinifaciens type strain (6091).

  Standards in genomic sciences 20110701

• Increased RNA editing in EAAT2 pre-mRNA from amyotrophic lateral sclerosis patients: involvement of a cryptic polyadenylation site.

  Neuroscience letters 20110622

• A single zinc ion is sufficient for an active Trypanosoma brucei tRNA editing deaminase.

  The Journal of biological chemistry 20110610

• Development of miracle medicines from sialic acids.

  Proceedings of the Japan Academy. Series B, Physical and biological sciences 20110610

• Tetherin and its viral antagonists.

  Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 20110601

• Low-molecular-mass purine nucleoside phosphorylase: characterization and application in enzymatic synthesis of nucleoside antiviral drugs.

  Biotechnology letters 20110601

• A-to-I RNA editing is induced upon hypoxia.

  Shock (Augusta, Ga.) 20110601

• Metabolomic analysis of liver and skeletal muscle tissues in C57BL/6J and DBA/2J mice exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin.

  Molecular bioSystems 20110601

• Effect of MANT-nucleotides on L-type calcium currents in murine cardiomyocytes.

  Naunyn-Schmiedeberg's archives of pharmacology 20110601

• Functional selectivity of adenosine receptor ligands.

  Purinergic signalling 20110601

• Changes in the metabolic profile of rat liver after α-tocopherol deficiency as revealed by metabolomics analysis.

  NMR in biomedicine 20110601

• The therapeutic potential of adenosine triphosphate as an immune modulator in the treatment of HIV/AIDS: a combination approach with HAART.

  Current HIV research 20110601

• 4-Pyridone-3-carboxamide-1-β-D-ribonucleoside triphosphate (4PyTP), a novel NAD metabolite accumulating in erythrocytes of uremic children: a biomarker for a toxic NAD analogue in other tissues?

  Toxins 20110601

• Cytogenetic methods for detection of oxidative stress and evaluation of antioxidant therapy in hepatitis C infection.

  Hepatitis monthly 20110601

• Nuclear Factor κB and Adenosine Receptors: Biochemical and Behavioral Profiling.

  Current neuropharmacology 20110601

• The nuclear RNA polymerase II surveillance system targets polymerase III transcripts.

  The EMBO journal 20110504

• ADAR2 editing enzyme is a novel human immunodeficiency virus-1 proviral factor.

  The Journal of general virology 20110501

• Inosine augments the effects of a Nogo receptor blocker and of environmental enrichment to restore skilled forelimb use after stroke.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20110420

• Arsenate and phosphate as nucleophiles at the transition states of human purine nucleoside phosphorylase.

  Biochemistry 20110405

• Dialysis modality-dependent changes in serum metabolites: accumulation of inosine and hypoxanthine in patients on haemodialysis.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20110401

• Spores of Bacillus cereus strain KBAB4 produced at 10 °C and 30 °C display variations in their properties.

  Food microbiology 20110401

• The role of extracellular adenosine in chemical neurotransmission in the hippocampus and Basal Ganglia: pharmacological and clinical aspects.

  Current topics in medicinal chemistry 20110401

• Simultaneous determination of 5'-monophosphate nucleotides in infant formulas by HPLC-MS.

  Journal of chromatographic science 20110401

• Profile of nucleotides and nucleosides in Taiwanese human milk.

  Pediatrics and neonatology 20110401

• Changes in Adenosine Deaminase Activity in Patients with Type 2 Diabetes Mellitus and Effect of DPP-4 Inhibitor Treatment on ADA Activity.

  Diabetes & metabolism journal 20110401

• Adenosine deaminases acting on RNA (ADARs) are both antiviral and proviral.

  Virology 20110315

• Engineered alterations in RNA editing modulate complex behavior in Drosophila: regulatory diversity of adenosine deaminase acting on RNA (ADAR) targets.

  The Journal of biological chemistry 20110311

• Evaluation of Bacillus strains as model systems for the work on Bacillus anthracis spores.

  International journal of food microbiology 20110301

• No shot in the dark: myxozoans chemically detect fresh fish.

  International journal for parasitology 20110301

• Arabidopsis nucleoside hydrolases involved in intracellular and extracellular degradation of purines.

  The Plant journal : for cell and molecular biology 20110301

• Influence of dietary nano elemental selenium on growth performance, tissue selenium distribution, meat quality, and glutathione peroxidase activity in Guangxi Yellow chicken.

  Poultry science 20110301

• Consensus-phenotype integration of transcriptomic and metabolomic data implies a role for metabolism in the chemosensitivity of tumour cells.

  PLoS computational biology 20110301

• Paradoxical interplay of viral and cellular functions.

  Viruses 20110301

• Measuring single small molecule binding via rupture forces of a split aptamer.

  Journal of the American Chemical Society 20110223

• Methylthioinosine phosphorylase from Pseudomonas aeruginosa. Structure and annotation of a novel enzyme in quorum sensing.

  Biochemistry 20110222

• Determination of the nucleosides and nucleobases in Tuber samples by dispersive solid-phase extraction combined with liquid chromatography-mass spectrometry.

  Analytica chimica acta 20110221

• Systems responses of rats to aflatoxin B1 exposure revealed with metabonomic changes in multiple biological matrices.

  Journal of proteome research 20110204

• Nucleotides and their degradation products during processing of dry-cured ham, measured by HPLC and an enzyme sensor.

  Meat science 20110201

• Elucidating the inosinome: global approaches to adenosine-to-inosine RNA editing.

  Nature reviews. Genetics 20110201

• Deoxycytidine production by metabolically engineered Corynebacterium ammoniagenes.

  Journal of microbiology (Seoul, Korea) 20110201

• Metabolomics as a powerful tool for molecular quality assessment of the fish Sparus aurata.

  Nutrients 20110201

• Adenosine-to-inosine RNA editing affects trafficking of the gamma-aminobutyric acid type A (GABA(A)) receptor.

  The Journal of biological chemistry 20110121

• Does RNA editing play a role in the development of urinary bladder cancer?

  Urologic oncology 20110101

• A rapid and simple chemiluminescence method for screening levels of inosine and hypoxanthine in non-traumatic chest pain patients.

  Luminescence : the journal of biological and chemical luminescence 20110101

• Substitution by inosine at the 3'-ultimate and penultimate positions of 16S rRNA gene universal primers.

  Microbial ecology 20110101

• Improvement of mitochondrial energy and oxidative balance during intestinal differentiation.

  Mitochondrion 20110101

• G protein-coupled receptor kinase 2 and arrestin2 regulate arterial smooth muscle P2Y-purinoceptor signalling.

  Cardiovascular research 20110101

• Enhancement of extracellular purine nucleoside accumulation by Bacillus strains through genetic modifications of genes involved in nucleoside export.

  Journal of industrial microbiology & biotechnology 20110101

• Neuroprotective effects of resveratrol on ischemic injury mediated by improving brain energy metabolism and alleviating oxidative stress in rats.

  Neuropharmacology 20110101

• Brassinolide-improved development of Brassica napus microspore-derived embryos is associated with increased activities of purine and pyrimidine salvage pathways.

  Planta 20110101

• Noninvasive detection of left-ventricular systolic dysfunction by acoustic cardiography in atrial fibrillation.

  Cardiology research and practice 20110101

• Neuroprotection by the Traditional Chinese Medicine, Tao-Hong-Si-Wu-Tang, against Middle Cerebral Artery Occlusion-Induced Cerebral Ischemia in Rats.

  Evidence-based complementary and alternative medicine : eCAM 20110101

• Effects of intragastric infusion of inosine monophosphate and L: -glutamate on vagal gastric afferent activity and subsequent autonomic reflexes.

  The journal of physiological sciences : JPS 20110101

• Purine nucleoside phosphorylase from Schistosoma mansoni in complex with ribose-1-phosphate.

  Journal of synchrotron radiation 20110101

• Adenosine deaminases acting on RNA, RNA editing, and interferon action.

  Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20110101

• Uptake of AMP, ADP, and ATP in Escherichia coli W.

  Bioscience, biotechnology, and biochemistry 20110101

• Mitochondrial dysfunction in Parkinson's disease: pathogenesis and neuroprotection.

  Parkinson's disease 20110101

• Metabolomic profiling for identification of novel potential biomarkers in cardiovascular diseases.

  Journal of biomedicine & biotechnology 20110101

• Local rheology of human neutrophils investigated using atomic force microscopy.

  International journal of biological sciences 20110101

• Sequencing and bioinformatics-based analyses of the microRNA transcriptome in hepatitis B-related hepatocellular carcinoma.

  PloS one 20110101

• Functional role of the polymorphic 647 T/C variant of ENT1 (SLC29A1) and its association with alcohol withdrawal seizures.

  PloS one 20110101

• RNA editing by mammalian ADARs.

  Advances in genetics 20110101

• Potential of immunosuppressive agents in cerebral ischaemia.

  The Indian journal of medical research 20110101

• Bacillus anthracis spore interactions with mammalian cells: relationship between germination state and the outcome of in vitro.

  BMC microbiology 20110101

• Perturbing A-to-I RNA editing using genetics and homologous recombination.

  Methods in molecular biology (Clifton, N.J.) 20110101

• Biochemical identification of A-to-I RNA editing sites by the inosine chemical erasing (ICE) method.

  Methods in molecular biology (Clifton, N.J.) 20110101

• Area, age and gender dependence of the nucleoside system in the brain: a review of current literature.

  Current topics in medicinal chemistry 20110101

• Metabolic network of nucleosides in the brain.

  Current topics in medicinal chemistry 20110101

• Expression of Drosophila adenosine deaminase in immune cells during inflammatory response.

  PloS one 20110101

• Modeling antibiotic and cytotoxic effects of the dimeric isoquinoline IQ-143 on metabolism and its regulation in Staphylococcus aureus, Staphylococcus epidermidis and human cells.

  Genome biology 20110101

• Visualization of spatiotemporal energy dynamics of hippocampal neurons by mass spectrometry during a kainate-induced seizure.

  PloS one 20110101

• Metabolites of purine nucleoside phosphorylase (NP) in serum have the potential to delineate pancreatic adenocarcinoma.

  PloS one 20110101

• Computational detection and functional analysis of human tissue-specific A-to-I RNA editing.

  PloS one 20110101

• Assay of the multiple energy-producing pathways of mammalian cells.

  PloS one 20110101

• Further improvements of the P. falciparum humanized mouse model.

  PloS one 20110101

• [The results of using cytoflavin in conservative treatment of patients with obliterating atherosclerosis of the lower extremity vessels].

  Vestnik khirurgii imeni I. I. Grekova 20110101

• Exploiting the high-resolution crystal structure of Staphylococcus aureus MenH to gain insight into enzyme activity.

  BMC structural biology 20110101

• A novel AMPK activator, WS070117, improves lipid metabolism discords in hamsters and HepG2 cells.

  Lipids in health and disease 20110101

• Sequence-based predictions of lipooligosaccharide diversity in the Neisseriaceae and their implication in pathogenicity.

  PloS one 20110101

• Rested and stressed farmed Atlantic cod (Gadus morhua) chilled in ice or slurry and effects on quality.

  Journal of food science 20110101

• More than 200 genes required for methane formation from H₂ and CO₂ and energy conservation are present in Methanothermobacter marburgensis and Methanothermobacter thermautotrophicus.

  Archaea (Vancouver, B.C.) 20110101

• Complete genome sequence of Mycoplasma suis and insights into its biology and adaption to an erythrocyte niche.

  PloS one 20110101

• Exploring metabolic pathway disruption in the subchronic phencyclidine model of schizophrenia with the Generalized Singular Value Decomposition.

  BMC systems biology 20110101

• Comparative transcriptome analysis of Bacillus subtilis responding to dissolved oxygen in adenosine fermentation.

  PloS one 20110101

• A 5'-uridine amplifies miRNA/miRNA* asymmetry in Drosophila by promoting RNA-induced silencing complex formation.

  Silence 20110101

• Nutritional and metabolic status of children with autism vs. neurotypical children, and the association with autism severity.

  Nutrition & metabolism 20110101

• Extensin network formation in Vitis vinifera callus cells is an essential and causal event in rapid and H(2)O(2)-induced reduction in primary cell wall hydration.

  BMC plant biology 20110101

• Biological responses to perfluorododecanoic acid exposure in rat kidneys as determined by integrated proteomic and metabonomic studies.

  PloS one 20110101

• Novel norovirus recombinants and of GII.4 sub-lineages associated with outbreaks between 2006 and 2010 in Belgium.

  Virology journal 20110101

• Global transcriptome response in Lactobacillus sakei during growth on ribose.

  BMC microbiology 20110101

• Identification of target antigens of anti-endothelial cell and anti-vascular smooth muscle cell antibodies in patients with giant cell arteritis: a proteomic approach.

  Arthritis research & therapy 20110101

• Use of specific chemical reagents for detection of modified nucleotides in RNA.

  Journal of nucleic acids 20110101

• Genetic diversity of Streptococcus suis isolates as determined by comparative genome hybridization.

  BMC microbiology 20110101

• DedA protein relates to action-mechanism of halicyclamine A, a marine spongean macrocyclic alkaloid, as an anti-dormant mycobacterial substance.

  Marine drugs 20110101

• Transgenic overexpression of Tcfap2c/AP-2gamma results in liver failure and intestinal dysplasia.

  PloS one 20110101

• A cell-based assay for RNA synthesis by the HCV polymerase reveals new insights on mechanism of polymerase inhibitors and modulation by NS5A.

  PloS one 20110101

• Comparative genomic reconstruction of transcriptional networks controlling central metabolism in the Shewanella genus.

  BMC genomics 20110101

• A nuclear magnetic resonance based approach to accurate functional annotation of putative enzymes in the methanogen Methanosarcina acetivorans.

  BMC genomics 20110101

• Assessment of bioflocculant production by Bacillus sp. Gilbert, a marine bacterium isolated from the bottom sediment of Algoa Bay.

  Marine drugs 20110101

• Use of nucleic Acid analogs for the study of nucleic Acid interactions.

  Journal of nucleic acids 20110101

• IPNV with high and low virulence: host immune responses and viral mutations during infection.

  Virology journal 20110101

• Molecular basis for chiral selection in RNA aminoacylation.

  International journal of molecular sciences 20110101

• Identification of a novel LCA5 mutation in a Pakistani family with Leber congenital amaurosis and cataracts.

  Molecular vision 20110101

• In situ dividing and phagocytosing retinal microglia express nestin, vimentin, and NG2 in vivo.

  PloS one 20110101

• Metabolomic profile of hepatitis C virus-infected hepatocytes.

  PloS one 20110101

• YwdL in Bacillus cereus: its role in germination and exosporium structure.

  PloS one 20110101

• Biochemical measurement of neonatal hypoxia.

  Journal of visualized experiments : JoVE 20110101

• Reduced expression of brain-enriched microRNAs in glioblastomas permits targeted regulation of a cell death gene.

  PloS one 20110101

• [Radiation protectors within the radiation safety system for extended duration exploration missions].

  Aviakosmicheskaia i ekologicheskaia meditsina = Aerospace and environmental medicine 20110101

• Agent-based dynamic knowledge representation of Pseudomonas aeruginosa virulence activation in the stressed gut: Towards characterizing host-pathogen interactions in gut-derived sepsis.

  Theoretical biology & medical modelling 20110101

• Differential proteome analysis of human embryonic kidney cell line (HEK-293) following mycophenolic acid treatment.

  Proteome science 20110101

• Genome of Mycoplasma haemofelis, unraveling its strategies for survival and persistence.

  Veterinary research 20110101

• Chemosensory learning in the cortex.

  Frontiers in systems neuroscience 20110101

• The Cryptosporidium parvum kinome.

  BMC genomics 20110101

• IL-4 amplifies the pro-inflammatory effect of adenosine in human mast cells by changing expression levels of adenosine receptors.

  PloS one 20110101

• Site-selective versus promiscuous A-to-I editing.

  Wiley interdisciplinary reviews. RNA 20110101

• Evolution under environmental stress at macro- and microscales.

  Genome biology and evolution 20110101

• Some aspects of purinergic signaling in the ventricular system of porcine brain.

  Acta veterinaria Scandinavica 20110101

• PAP and NT5E inhibit nociceptive neurotransmission by rapidly hydrolyzing nucleotides to adenosine.

  Molecular pain 20110101

• Safety and efficacy of nicotinamide in the management of hyperphosphatemia in patients on hemodialysis.

  Indian journal of nephrology 20110101

• Very few RNA and DNA sequence differences in the human transcriptome.

  PloS one 20110101

• Inosine-containing RNA is a novel innate immune recognition element and reduces RSV infection.

  PloS one 20110101

• Enzymatic properties of Staphylococcus aureus adenosine synthase (AdsA).

  BMC biochemistry 20110101

• Exosomes from Plasmodium yoelii-infected reticulocytes protect mice from lethal infections.

  PloS one 20110101

• Nerve and behavioral responses of mice to various umami substances.

  Bioscience, biotechnology, and biochemistry 20110101

• Plasmodium falciparum parasites are killed by a transition state analogue of purine nucleoside phosphorylase in a primate animal model.

  PloS one 20110101

• Serum metabolic profile in multiple sclerosis patients.

  Multiple sclerosis international 20110101

• When Does ALS Start? ADAR2-GluA2 Hypothesis for the Etiology of Sporadic ALS.

  Frontiers in molecular neuroscience 20110101

• A showcase of bench-to-bedside regenerative medicine at the 2010 ASNTR.

  TheScientificWorldJournal 20110101

• A practical approach to T-cell receptor cloning and expression.

  PloS one 20110101

• Sequencing by ligation variation with endonuclease V digestion and deoxyinosine-containing query oligonucleotides.

  BMC genomics 20110101

• Electronic noses and tongues: applications for the food and pharmaceutical industries.

  Sensors (Basel, Switzerland) 20110101

• Purine biosynthesis in archaea: variations on a theme.

  Biology direct 20110101

• Genotypic and pathotypic characterization of Newcastle disease viruses from India.

  PloS one 20110101

• An insight into the sialome of Simulium guianense (DIPTERA:SIMulIIDAE), the main vector of River Blindness Disease in Brazil.

  BMC genomics 20110101

• The role of ATP in sleep regulation.

  Frontiers in neurology 20110101

• Lack of phenotypic effect of triallelic variation in SPATA7 in a family with Leber congenital amaurosis resulting from CRB1 mutations.

  Molecular vision 20110101

• A genomic reappraisal of symbiotic function in the aphid/Buchnera symbiosis: reduced transporter sets and variable membrane organisations.

  PloS one 20110101

• Aquaporin 4 is a Ubiquitously Expressed Isoform in the Dogfish (Squalus acanthias) Shark.

  Frontiers in physiology 20110101

• Proliferation inhibition, cell cycle arrest and apoptosis induced in HL-60 cells by a natural diterpene ester from Daphne mucronata.

  Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 20110101

• [Some inhibitors of purine nucleoside phosphorylase].

  Biomeditsinskaia khimiia 20110101

• Reconstruction of Purine Metabolism in Bacillus subtilis to Obtain the Strain Producer of AICAR: A New Drug with a Wide Range of Therapeutic Applications.

  Acta naturae 20110101

• [Effect of preparation 'Korargin' on metabolic syndrome manifestations in adult and old rats exposed to x-ray irradiation].

  Likars'ka sprava 20110101

• The Cys319 loop modulates the transition between dehydrogenase and hydrolase conformations in inosine 5'-monophosphate dehydrogenase.

  Biochemistry 20101221

• Conformational dynamics in human purine nucleoside phosphorylase with reactants and transition-state analogues.

  The journal of physical chemistry. B 20101216

• Translocation of the Na+/H+ exchanger 1 (NHE1) in cardiomyocyte responses to insulin and energy-status signalling.

  The Biochemical journal 20101215

• Adenosine A2A receptors and uric acid mediate protective effects of inosine against TNBS-induced colitis in rats.

  European journal of pharmacology 20101215

• Ribonucleoside triphosphates as substrate of human immunodeficiency virus type 1 reverse transcriptase in human macrophages.

  The Journal of biological chemistry 20101210

• Adenine, guanine and pyridine nucleotides in blood during physical exercise and restitution in healthy subjects.

  European journal of applied physiology 20101201

• Adenosine and inosine release during hypoxia in the isolated spinal cord of neonatal rats.

  British journal of pharmacology 20101201

• Brain hypoxanthine concentration correlates to lactate/pyruvate ratio but not intracranial pressure in patients with acute liver failure.

  Journal of hepatology 20101201

• Endogenous luminal surface adenosine signaling regulates duodenal bicarbonate secretion in rats.

  The Journal of pharmacology and experimental therapeutics 20101201

• RNA editing in P transposable element read-through transcripts in Drosophila melanogaster.

  Genetica 20101201

• Profiles of purine metabolism in leaves and roots of Camellia sinensis seedlings.

  Plant & cell physiology 20101201

• [Optimal immunosuppressive therapy based on pharmacokinetics and pharmacodynamics of antimetabolites in clinical practice].

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20101201

• A quantitative systems approach reveals dynamic control of tRNA modifications during cellular stress.

  PLoS genetics 20101201

• 1,2,3-Tri-O-acetyl-5-de-oxy-d-ribofuran-ose.

  Acta crystallographica. Section E, Structure reports online 20101201

• ITPA protein, an enzyme that eliminates deaminated purine nucleoside triphosphates in cells.

  Mutation research 20101128

• Chemoselective multicomponent one-pot assembly of purine precursors in water.

  Journal of the American Chemical Society 20101124

• Prevention of autosomal dominant retinitis pigmentosa by systemic drug therapy targeting heat shock protein 90 (Hsp90).

  Human molecular genetics 20101115

• Metabolic profiling detects field effects in nondysplastic tissue from esophageal cancer patients.

  Cancer research 20101115

• Selective inhibition of ADAR2-catalyzed editing of the serotonin 2c receptor pre-mRNA by a helix-threading peptide.

  Organic & biomolecular chemistry 20101107

• Inosine 5'-monophosphate dehydrogenase 1 haplotypes and association with mycophenolate mofetil gastrointestinal intolerance in pediatric heart transplant patients.

  Pediatric transplantation 20101101

• Exploring new inhibitors of Plasmodium falciparum purine nucleoside phosphorylase.

  European journal of medicinal chemistry 20101101

• Effect of the inosine 5'-monophosphate dehydrogenase inhibitor BMS-566419 on renal fibrosis in unilateral ureteral obstruction in rats.

  International immunopharmacology 20101101

• Regulation of Na+/K+ ATPase transport velocity by RNA editing.

  PLoS biology 20101101

• [Inefficient A-to-I RNA editing and ALS].

  Rinsho shinkeigaku = Clinical neurology 20101101

• Editing of Epstein-Barr virus-encoded BART6 microRNAs controls their dicer targeting and consequently affects viral latency.

  The Journal of biological chemistry 20101022

• One-pot etherification of purine nucleosides and pyrimidines.

  Organic letters 20101015

• Electrochemical genotyping and detection of single-nucleotide polymorphisms based on junction-probe containing 2'-deoxyinosine.

  Chemical communications (Cambridge, England) 20101007

• Endonuclease V-mediated deoxyinosine excision repair in vitro.

  DNA repair 20101005

• Local administration of uridine suppresses the cardinal features of asthmatic airway inflammation.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20101001

• Carbocyclic 6-benzylthioinosine analogues as subversive substrates of Toxoplasma gondii adenosine kinase: biological activities and selective toxicities.

  Biochemical pharmacology 20101001

• Extreme nucleoside concentrations in a marine annelid: a novel nucleoside storing cell in the polychaete Nereis virens.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20101001

• Metabolomic profiling reveals biochemical pathways and biomarkers associated with pathogenesis in cystic fibrosis cells.

  The Journal of biological chemistry 20101001

• Differential expression of functional nucleoside transporters in non-differentiated and differentiated human endothelial progenitor cells.

  Placenta 20101001

• Lymphocyte-based determination of susceptibility to malignant hyperthermia: a pilot study in swine.

  Anesthesiology 20101001

• Inosine cyanoethylation identifies A-to-I RNA editing sites in the human transcriptome.

  Nature chemical biology 20101001

• Correlation between polymorphisms in ADSL and GARS-AIRS-GART genes with inosine 5'-monophosphate (IMP) contents in Beijing-you chickens.

  British poultry science 20101001

• Adenosine Deaminase Levels in CSF of Tuberculous Meningitis Patients.

  Journal of clinical medicine research 20101001

• Development and application of an HILIC-MS/MS method for the quantitation of nucleotides in infant formula.

  Journal of agricultural and food chemistry 20100922

• Induced loss of ADAR2 engenders slow death of motor neurons from Q/R site-unedited GluR2.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20100908

• Lower frequency of the low activity adenosine deaminase allelic variant (ADA1*2) in schizophrenic patients.

  Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) 20100901

• Assessment of the effects of dentifrice on periodontal disease biomarkers in gingival crevicular fluid.

  Journal of periodontology 20100901

• Blood uridine concentration may be an indicator of the degradation of pyrimidine nucleotides during physical exercise with increasing intensity.

  Journal of physiology and biochemistry 20100901

• Reversal of TNP-470-induced endothelial cell growth arrest by guanine and guanine nucleosides.

  The Journal of pharmacology and experimental therapeutics 20100901

• 1H, 13C and 15N NMR assignments for N6-isopentenyladenosine/inosine analogues.

  Magnetic resonance in chemistry : MRC 20100901

• Double-stranded RNAs containing multiple IU pairs are sufficient to suppress interferon induction and apoptosis.

  Nature structural & molecular biology 20100901

• Extracellular-purine metabolism in blood vessels (part I). Extracellular-purine level in blood of patients with abdominal aortic aneurysm.

  Nucleosides, nucleotides & nucleic acids 20100901

• [Effect of hepatoprotector remaxol infusion on liver function in obstructive jaundice model in rats].

  Eksperimental'naia i klinicheskaia farmakologiia 20100901

• Biosensor measurement of purine release from cerebellar cultures and slices.

  Purinergic signalling 20100901

• Determination of nucleotides, nucleosides and their transformation products in Cordyceps by ion-pairing reversed-phase liquid chromatography-mass spectrometry.

  Journal of chromatography. A 20100820

• The relationship between oxygen and adenosine in astrocytic cultures.

  Glia 20100815

• Structure and reactivity of Bacillus subtilis MenD catalyzing the first committed step in menaquinone biosynthesis.

  Journal of molecular biology 20100813

• Ion-pair high-performance liquid chromatography with diode array detection coupled to dual electrospray atmospheric pressure chemical ionization time-of-flight mass spectrometry for the determination of nucleotides in baby foods.

  Journal of chromatography. A 20100806

• Correlation of IMPDH1 gene polymorphisms with subclinical acute rejection and mycophenolic acid exposure parameters on day 28 after renal transplantation.

  Basic & clinical pharmacology & toxicology 20100801

• Inosine reduces pain-related behavior in mice: involvement of adenosine A1 and A2A receptor subtypes and protein kinase C pathways.

  The Journal of pharmacology and experimental therapeutics 20100801

• Effects of Na+ and H+ on steady-state and presteady-state currents of the human concentrative nucleoside transporter 3 (hCNT3).

  Pflugers Archiv : European journal of physiology 20100801

• Accumulation of gene-targeted Bacillus subtilis mutations that enhance fermentative inosine production.

  Applied microbiology and biotechnology 20100801

• Structure of Staphylococcus aureus adenylosuccinate lyase (PurB) and assessment of its potential as a target for structure-based inhibitor discovery.

  Acta crystallographica. Section D, Biological crystallography 20100801

• A screening pipeline for antiparasitic agents targeting cryptosporidium inosine monophosphate dehydrogenase.

  PLoS neglected tropical diseases 20100801

• [Simultaneous determination of 7 nucleosides in Asterias rollestoni using reversed-phase high performance liquid chromatography].

  Se pu = Chinese journal of chromatography 20100801

• (15)N Double-labeled guanosine from inosine through ring-opening-ring-closing and one-pot Pd-catalyzed C-O and C-N cross-coupling reactions.

  The Journal of organic chemistry 20100716

• Human BLCAP transcript: new editing events in normal and cancerous tissues.

  International journal of cancer 20100701

• Effect of taxifolin glycoside on atopic dermatitis-like skin lesions in NC/Nga mice.

  Phytotherapy research : PTR 20100701

• ADAR editing in double-stranded UTRs and other noncoding RNA sequences.

  Trends in biochemical sciences 20100701

• Comparative analysis of cerebrospinal fluid adenosine deaminase in tuberculous and non-tuberculous meningitis.

  Clinical neurology and neurosurgery 20100701

• Determination of serum adenosine deaminase and xanthine oxidase levels in patients with crimean-congo hemorrhagic fever.

  Clinics (Sao Paulo, Brazil) 20100701

• New trends in nucleoside biotechnology.

  Acta naturae 20100701

• Analysis of seven purines and pyrimidines in pork meat products by ultra high performance liquid chromatography-tandem mass spectrometry.

  Journal of chromatography. A 20100625

• Proteomic screen for potential regulators of M-phase entry and quality of meiotic resumption in Xenopus laevis oocytes.

  Journal of proteomics 20100616

• Comparative analysis of Bacillus weihenstephanensis KBAB4 spores obtained at different temperatures.

  International journal of food microbiology 20100615

• Extracellular 3',5'-cAMP-adenosine pathway inhibits glomerular mesangial cell growth.

  The Journal of pharmacology and experimental therapeutics 20100601

• Identification of a second DNA binding site in human DNA methyltransferase 3A by substrate inhibition and domain deletion.

  Archives of biochemistry and biophysics 20100601

• Simultaneous determination of nine nucleosides and nucleobases in different Fritillaria species by HPLC-diode array detector.

  Journal of separation science 20100601

• Nucleotides and nucleosides in ovine and caprine milk during lactation.

  Journal of dairy science 20100601

• Successful pyrosequencing of GC-rich DNA sequences by partial substitution of deoxyguanosine with deoxyinosine.

  Diagnostic molecular pathology : the American journal of surgical pathology, part B 20100601

• Nucleotide-amino acid interactions in the L-His-IMP.MeOH.H(2)O complex.

  Acta crystallographica. Section C, Crystal structure communications 20100601

• Trypanosoma brucei modifies the tsetse salivary composition, altering the fly feeding behavior that favors parasite transmission.

  PLoS pathogens 20100601

• Age-related gene-specific changes of A-to-I mRNA editing in the human brain.

  Mechanisms of ageing and development 20100601

• Cortical overexpression of neuronal calcium sensor-1 induces functional plasticity in spinal cord following unilateral pyramidal tract injury in rat.

  PLoS biology 20100601

• Constraint-based model of Shewanella oneidensis MR-1 metabolism: a tool for data analysis and hypothesis generation.

  PLoS computational biology 20100601

• Sensitivity, specificity, negative and positive predictive values of adenosine deaminase in patients of tubercular and non-tubercular serosal effusion in India.

  Journal of clinical medicine research 20100601

• Historical perspectives in the development of antiviral agents against poxviruses.

  Viruses 20100601

• Structure-activity relationships of carbocyclic 6-benzylthioinosine analogues as subversive substrates of Toxoplasma gondii adenosine kinase.

  Bioorganic & medicinal chemistry 20100515

• Effects of L-alanine and inosine germinants on the elasticity of Bacillus anthracis spores.

  Langmuir : the ACS journal of surfaces and colloids 20100504

• Inhibitors of adenosine consuming parasites through polymer-assisted N-acylation of N6-substituted 5'-amino-5'-deoxyadenosines.

  Molecular diversity 20100501

• Modulation of serum uric acid levels by inosine in patients with multiple sclerosis does not affect blood pressure.

  Journal of human hypertension 20100501

• Permuted tRNA genes in the nuclear and nucleomorph genomes of photosynthetic eukaryotes.

  Molecular biology and evolution 20100501

• Metabolomic study of myocardial ischemia and intervention effects of Compound Danshen Tablets in rats using ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry.

  Journal of pharmaceutical and biomedical analysis 20100501

• Persistent growth of a human plasma-derived hepatitis C virus genotype 1b isolate in cell culture.

  PLoS pathogens 20100501

• A survey of genomic traces reveals a common sequencing error, RNA editing, and DNA editing.

  PLoS genetics 20100501

• Germinant receptor diversity and germination responses of four strains of the Bacillus cereus group.

  International journal of food microbiology 20100430

• Changes in purines concentration in the cerebrospinal fluid of patients experiencing pain: a case-control study.

  Neuroscience letters 20100426

• A mammalian reporter system for fast and quantitative detection of intracellular A-to-I RNA editing levels.

  Analytical biochemistry 20100415

• Molecular gastronomy: a new emerging scientific discipline.

  Chemical reviews 20100414

• Chronic morphine treatment impaired hippocampal long-term potentiation and spatial memory via accumulation of extracellular adenosine acting on adenosine A1 receptors.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20100407

• Gender- and age-dependent changes in nucleoside levels in the cerebral cortex and white matter of the human brain.

  Brain research bulletin 20100405

• Dissecting interactions between nucleosides and germination receptors in Bacillus cereus 569 spores.

  Microbiology (Reading, England) 20100401

• Isoprinosine affects serum cytokine levels in healthy adults.

  Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20100401

• Agmatine-conjugated cytidine in a tRNA anticodon is essential for AUA decoding in archaea.

  Nature chemical biology 20100401

• Boosting endogenous neuroprotection in multiple sclerosis: the ASsociation of Inosine and Interferon beta in relapsing- remitting Multiple Sclerosis (ASIIMS) trial.

  Multiple sclerosis (Houndmills, Basingstoke, England) 20100401

• Novel riboswitch ligand analogs as selective inhibitors of guanine-related metabolic pathways.

  PLoS pathogens 20100401

• Role of Adenosine Deaminase Estimation in Differentiation of Tuberculous and Non-tuberculous Exudative Pleural Effusions.

  Journal of clinical medicine research 20100401

• Selectivity of Enzymatic Conversion of Oligonucleotide Probes during Nucleotide Polymorphism Analysis of DNA.

  Acta naturae 20100401

• Flexible recognition of the tRNA G18 methylation target site by TrmH methyltransferase through first binding and induced fit processes.

  The Journal of biological chemistry 20100319

• Stability of DNA duplexes containing hypoxanthine (inosine): gas versus solution phase and biological implications.

  The Journal of organic chemistry 20100319

• Intramolecular cation-pi interactions as the driving force to restrict the conformation of certain nucleosides.

  The Journal of organic chemistry 20100319

• Adenosine deaminase modulation of telomerase activity and replicative senescence in human CD8 T lymphocytes.

  Journal of immunology (Baltimore, Md. : 1950) 20100315

• Nucleoside map of the human central nervous system.

  Neurochemical research 20100301

• Preoxygenated hemoglobin-based oxygen carrier HBOC-201 annihilates myocardial ischemia during brief coronary artery occlusion in pigs.

  American journal of physiology. Heart and circulatory physiology 20100301

• Cloning, purification and characterisation of a recombinant purine nucleoside phosphorylase from Bacillus halodurans Alk36.

  Extremophiles : life under extreme conditions 20100301

• Multiple receptor tyrosine kinases are expressed in adult rat retinal ganglion cells as revealed by single-cell degenerate primer polymerase chain reaction.

  Upsala journal of medical sciences 20100301

• A novel tissue-specific alternatively spliced form of the A-to-I RNA editing enzyme ADAR2.

  RNA biology 20100301

• Genomic evidence for complementary purine metabolism in the pea aphid, Acyrthosiphon pisum, and its symbiotic bacterium Buchnera aphidicola.

  Insect molecular biology 20100301

• Adenosine deaminase activity in COPD patients and healthy subjects.

  Iranian journal of allergy, asthma, and immunology 20100301

• Role of transmembrane domain 4 in ligand permeation by Crithidia fasciculata equilibrative nucleoside transporter 2 (CfNT2).

  The Journal of biological chemistry 20100226

• Study on intestinal absorption sites of mizoribine and ribavirin, substrates for concentrative nucleoside transporter(s), in rats.

  European journal of pharmacology 20100225

• The structural basis of Cryptosporidium -specific IMP dehydrogenase inhibitor selectivity.

  Journal of the American Chemical Society 20100203

• The preparation, germination properties and stability of superdormant spores of Bacillus cereus.

  Journal of applied microbiology 20100201

• An inosine 5'-monophosphate dehydrogenase 2 single-nucleotide polymorphism impairs the effect of mycophenolic acid.

  The pharmacogenomics journal 20100201

• Promoting axonal rewiring to improve outcome after stroke.

  Neurobiology of disease 20100201

• [Molecular cloning, gene expression and characterization of purine nucleoside phosphorylase from Pseudoalteromonas sp. XM2107].

  Wei sheng wu xue bao = Acta microbiologica Sinica 20100201

• Complementary retrieval of 16S rRNA gene sequences using broad-range primers with inosine at the 3'-terminus: implications for the study of microbial diversity.

  FEMS microbiology ecology 20100101

• Effect of the inosine 5'-monophosphate dehydrogenase inhibitor BMS-566419 on rat cardiac allograft rejection.

  International immunopharmacology 20100101

• Oligodendrocytes: biology and pathology.

  Acta neuropathologica 20100101

• Effect of the histone deacetylase inhibitor trichostatin a on the metabolome of cultured primary hepatocytes.

  Journal of proteome research 20100101

• The role of Bacillus anthracis germinant receptors in germination and virulence.

  Molecular microbiology 20100101

• A computational screen for site selective A-to-I editing detects novel sites in neuron specific Hu proteins.

  BMC bioinformatics 20100101

• Adenosine binding to low-molecular-weight purine nucleoside phosphorylase: the structural basis for recognition based on its complex with the enzyme from Schistosoma mansoni.

  Acta crystallographica. Section D, Biological crystallography 20100101

• Inosine monophosphate dehydrogenase variability in renal transplant patients on long-term mycophenolate mofetil therapy.

  British journal of clinical pharmacology 20100101

• Structural biology of human H3K9 methyltransferases.

  PloS one 20100101

• Control of ATP homeostasis during the respiro-fermentative transition in yeast.

  Molecular systems biology 20100101

• Differentiation of intestinal epithelial cells mediated by cell confluence and/or exogenous nucleoside supplementation.

  Cells, tissues, organs 20100101

• Uptake of purines in Plasmodium falciparum-infected human erythrocytes is mostly mediated by the human equilibrative nucleoside transporter and the human facilitative nucleobase transporter.

  Malaria journal 20100101

• Alternative splicing and extensive RNA editing of human TPH2 transcripts.

  PloS one 20100101

• Expression and functional activity of nucleoside transporters in human choroid plexus.

  Cerebrospinal fluid research 20100101

• Carbohydrate vs protein supplementation for recovery of neuromuscular function following prolonged load carriage.

  Journal of the International Society of Sports Nutrition 20100101

• Role of the gerP operon in germination and outgrowth of Bacillus anthracis spores.

  PloS one 20100101

• Alterations in adenosine metabolism and signaling in patients with chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis.

  PloS one 20100101

• Constructing fluorogenic Bacillus spores (F-spores) via hydrophobic decoration of coat proteins.

  PloS one 20100101

• Successful stabilisation of nephropathy in a patient with POEMS (polyneuropathy, organomegaly, endocrinopathy, M-band, skin changes) syndrome on treatment with mycophenolate and steroids: a case report.

  Journal of medical case reports 20100101

• NAD+ metabolite levels as a function of vitamins and calorie restriction: evidence for different mechanisms of longevity.

  BMC chemical biology 20100101

• [RNA editing in eukaryotic genome expression].

  Genetika 20100101

• Proteome diversification by adenosine to inosine RNA editing.

  RNA biology 20100101

• Quality evaluation of mycelial Antrodia camphorata using high-performance liquid chromatography (HPLC) coupled with diode array detector and mass spectrometry (DAD-MS).

  Chinese medicine 20100101

• Homeostatic imbalance of purine catabolism in first-episode neuroleptic-naïve patients with schizophrenia.

  PloS one 20100101

• Diverse functions for DNA and RNA editing in the immune system.

  RNA biology 20100101

• Protection of photoreceptors in a mouse model of RP10.

  Advances in experimental medicine and biology 20100101

• Adaptation of group A Streptococcus to human amniotic fluid.

  PloS one 20100101

• An insight into the sialome of Glossina morsitans morsitans.

  BMC genomics 20100101

• The transition from noncoded to coded protein synthesis: did coding mRNAs arise from stability-enhancing binding partners to tRNA?

  Biology direct 20100101

• Cell-associated hemolysis activity in the clinical strain of Pseudomonas fluorescens MFN1032.

  BMC microbiology 20100101

• Ultra-high throughput sequencing-based small RNA discovery and discrete statistical biomarker analysis in a collection of cervical tumours and matched controls.

  BMC biology 20100101

• The immunosuppressive drug mizoribine directly prevents podocyte injury in puromycin aminonucleoside nephrosis.

  Nephron. Experimental nephrology 20100101

• Active site plasticity revealed from the structure of the enterobacterial N-ribohydrolase RihA bound to a competitive inhibitor.

  BMC structural biology 20100101

• Characteristics of transposable element exonization within human and mouse.

  PloS one 20100101

• Duplication, divergence and persistence in the Phytochrome photoreceptor gene family of cottons (Gossypium spp.).

  BMC plant biology 20100101

• Alu sequences in undifferentiated human embryonic stem cells display high levels of A-to-I RNA editing.

  PloS one 20100101

• Impact of RNA editing on functions of the serotonin 2C receptor in vivo.

  Frontiers in neuroscience 20100101

• Inborn errors of energy metabolism associated with myopathies.

  Journal of biomedicine & biotechnology 20100101

• Large mesenteric cyst mimicking tuberculous ascites.

  Case reports in medicine 20100101

• A metabolic model of human erythrocytes: practical application of the E-Cell Simulation Environment.

  Journal of biomedicine & biotechnology 20100101

• A liquid chromatographic method for routine analysis of 5'-mononucleotides in pediatric formulas.

  Journal of AOAC International 20100101

• Over-expression of adenosine deaminase in mouse podocytes does not reverse puromycin aminonucleoside resistance.

  BMC nephrology 20100101

• Large-scale analysis of structural, sequence and thermodynamic characteristics of A-to-I RNA editing sites in human Alu repeats.

  BMC genomics 20100101

• A new family of phosphoinositide phosphatases in microorganisms: identification and biochemical analysis.

  BMC genomics 20100101

• Forever young: mechanisms of natural anoxia tolerance and potential links to longevity.

  Oxidative medicine and cellular longevity 20100101

• Antimalarial drug targets in Plasmodium falciparum predicted by stage-specific metabolic network analysis.

  BMC systems biology 20100101

• Overexpression of inosine 5'-monophosphate dehydrogenase type II mediates chemoresistance to human osteosarcoma cells.

  PloS one 20100101

• Cytidine-Ag+-purine base complexes as studied by electrospray ionization mass spectrometry.

  European journal of mass spectrometry (Chichester, England) 20100101

• Reconstruction and flux-balance analysis of the Plasmodium falciparum metabolic network.

  Molecular systems biology 20100101

• Induction of erythroid differentiation in human erythroleukemia cells by depletion of malic enzyme 2.

  PloS one 20100101

• APOBEC-1-mediated RNA editing.

  Wiley interdisciplinary reviews. Systems biology and medicine 20100101

• Transfer RNA modifications and genes for modifying enzymes in Arabidopsis thaliana.

  BMC plant biology 20100101

• Development of QSAR model for immunomodulatory activity of natural coumarinolignoids.

  Drug design, development and therapy 20100101

• Detecting variants with Metabolic Design, a new software tool to design probes for explorative functional DNA microarray development.

  BMC bioinformatics 20100101

• Base sequence context effects on nucleotide excision repair.

  Journal of nucleic acids 20100101

• Predicting enzyme targets for cancer drugs by profiling human metabolic reactions in NCI-60 cell lines.

  BMC bioinformatics 20100101

• Elevated Levels of DNA Strand Breaks Induced by a Base Analog in the Human Cell Line with the P32T ITPA Variant.

  Journal of nucleic acids 20100101

• Development of a Novel Fluorescence Assay Based on the Use of the Thrombin-Binding Aptamer for the Detection of O-Alkylguanine-DNA Alkyltransferase Activity.

  Journal of nucleic acids 20100101

• Interaction of human dipeptidyl peptidase IV and human immunodeficiency virus type-1 transcription transactivator in Sf9 cells.

  Virology journal 20100101

• Identification of Aluminum Responsive Genes in Al-Tolerant Soybean Line PI 416937.

  International journal of plant genomics 20100101

• Organization of GC/MS and LC/MS metabolomics data into chemical libraries.

  Journal of cheminformatics 20100101

• Anaerobic energy expenditure and mechanical efficiency during exhaustive leg press exercise.

  PloS one 20100101

• Consistent levels of A-to-I RNA editing across individuals in coding sequences and non-conserved Alu repeats.

  BMC genomics 20100101

• Analysis of Monosodium l-Glutamate in Food Products by High-Performance Thin Layer Chromatography.

  Journal of young pharmacists : JYP 20100101

• Effects of inosine on reperfusion injury after cardiopulmonary bypass.

  Journal of cardiothoracic surgery 20100101

• Sleep-waking discharge of ventral tuberomammillary neurons in wild-type and histidine decarboxylase knock-out mice.

  Frontiers in behavioral neuroscience 20100101

• [Effect of prenatal hypobaric hypoxia on activity of the rat brain phosphoinositide system].

  Zhurnal evoliutsionnoi biokhimii i fiziologii 20100101

• Substitutional A-to-I RNA editing.

  Wiley interdisciplinary reviews. RNA 20100101

• Differential proteomic analysis highlights metabolic strategies associated with balhimycin production in Amycolatopsis balhimycina chemostat cultivations.

  Microbial cell factories 20100101

• Serum microRNAs as non-invasive biomarkers for cancer.

  Molecular cancer 20100101

• Factors influencing cerebral plasticity in the normal and injured brain.

  Frontiers in human neuroscience 20100101

• RNA editing of nuclear transcripts in Arabidopsis thaliana.

  BMC genomics 20100101

• Constraint-based modeling analysis of the metabolism of two Pelobacter species.

  BMC systems biology 20100101

• Analysis of microRNA expression in the prepubertal testis.

  PloS one 20100101

• Alterations of NO synthase isoforms in brain and kidney of rats with genetic and salt hypertension.

  Physiological research 20100101

• Experimental models of renal disease and the cardiovascular system.

  The open cardiovascular medicine journal 20100101

• Molecular cloning, characterization, and expression analysis of an estrogen receptor-related receptor homologue in the cricket, Teleogryllus emma.

  Journal of insect science (Online) 20100101

• Clinical and experimental advances in regeneration of spinal cord injury.

  Journal of tissue engineering 20100101

• Long-term (trophic) purinergic signalling: purinoceptors control cell proliferation, differentiation and death.

  Cell death & disease 20100101

• Update on the management of chronic eczema: new approaches and emerging treatment options.

  Clinical, cosmetic and investigational dermatology 20100101

• Phylogenetic position of an uncharacterized Brazilian strain of bovine papillomavirus in the genus Xipapillomavirus based on sequencing of the L1 open reading frame.

  Genetics and molecular biology 20100101

• RNA editing and its control in hepatitis delta virus replication.

  Viruses 20100101

• Interaction of host cellular proteins with components of the hepatitis delta virus.

  Viruses 20100101

• Adenosine deamination in human transcripts generates novel microRNA binding sites.

  Human molecular genetics 20091215

• Pharmacokinetic role of protein binding of mycophenolic acid and its glucuronide metabolite in renal transplant recipients.

  Journal of pharmacokinetics and pharmacodynamics 20091201

• Physiological role of carbon dioxide in spore germination of Clostridium perfringens S40.

  Journal of bioscience and bioengineering 20091201

• Marine benthic diatoms contain compounds able to induce leukemia cell death and modulate blood platelet activity.

  Marine drugs 20091201

• 3-O-methylfunicone, a selective inhibitor of mammalian Y-family DNA polymerases from an Australian sea salt fungal strain.

  Marine drugs 20091201

• Isolation of C11 cyclopentenones from two didemnid species, Lissoclinum sp. and Diplosoma sp.

  Marine drugs 20091201

• Effect of cyclic bis(3'-5')diguanylic acid and its analogs on bacterial biofilm formation.

  FEMS microbiology letters 20091201

• [RNA modification/editing and regulatory gene expression].

  Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 20091201

• Activation of the Antiviral Kinase PKR and Viral Countermeasures.

  Viruses 20091201

• Revisiting plus-strand DNA synthesis in retroviruses and long terminal repeat retrotransposons: dynamics of enzyme: substrate interactions.

  Viruses 20091201

• All known human rhinovirus species are present in sputum specimens of military recruits during respiratory infection.

  Viruses 20091201

• Extracellular 2',3'-cAMP is a source of adenosine.

  The Journal of biological chemistry 20091127

• Adenosine deaminase ADAR1 increases gene expression at the translational level by decreasing protein kinase PKR-dependent eIF-2alpha phosphorylation.

  Journal of molecular biology 20091106

• Adenosine-to-inosine genetic recoding is required in the adult stage nervous system for coordinated behavior in Drosophila.

  The Journal of biological chemistry 20091106

• High-dose folate and dietary purines promote scavenging of peroxynitrite-derived radicals--clinical potential in inflammatory disorders.

  Medical hypotheses 20091101

• Identification and characterization of inosine 5-monophosphate dehydrogenase in Streptococcus suis type 2.

  Microbial pathogenesis 20091101

• Cytoprotective effects of adenosine and inosine in an in vitro model of acute tubular necrosis.

  British journal of pharmacology 20091101

• Towards the synthesis of inosine building blocks for the preparation of oligonucleotides with hydrophobic alkyl chains between the nucleotide units.

  Molecules (Basel, Switzerland) 20091026

• RNA-specific adenosine deaminase ADAR1 suppresses measles virus-induced apoptosis and activation of protein kinase PKR.

  The Journal of biological chemistry 20091023

• Editing independent effects of ADARs on the miRNA/siRNA pathways.

  The EMBO journal 20091021

• Random amplified polymorphic DNA (RAPD) analysis and the nucleosides assessment of fungal strains isolated from natural Cordyceps sinensis.

  Journal of pharmaceutical and biomedical analysis 20091015

• Determination of nucleosides and nucleobases in different species of Cordyceps by capillary electrophoresis-mass spectrometry.

  Journal of pharmaceutical and biomedical analysis 20091015

• A potentially versatile nucleotide hydrolysis activity of group II chaperonin monomers from Thermoplasma acidophilum.

  Biochemistry 20091013

• Structural basis for enzymatic evolution from a dedicated ADP-ribosyl cyclase to a multifunctional NAD hydrolase.

  The Journal of biological chemistry 20091002

• ITPase-deficient mice show growth retardation and die before weaning.

  Cell death and differentiation 20091001

• Potential therapeutic advantages of guanosine over inosine in multiple sclerosis.

  Medical hypotheses 20091001

• Comparison of elimination and cardiovascular effects of adenine nucleosides administered intrapericardially or intravenously in anesthetized dog.

  Journal of cardiovascular pharmacology 20091001

• RNA editing: a driving force for adaptive evolution?

  BioEssays : news and reviews in molecular, cellular and developmental biology 20091001

• Evidence that endogenous inosine and adenosine-mediated hyperglycaemia during ischaemia-reperfusion through A3 adenosine receptors.

  Autonomic & autacoid pharmacology 20091001

• 1+1 = 3: a fusion of 2 enzymes in the methionine salvage pathway of Tetrahymena thermophila creates a trifunctional enzyme that catalyzes 3 steps in the pathway.

  PLoS genetics 20091001

• N-methyl-D-aspartate-evoked adenosine and inosine release from neurons requires extracellular calcium.

  Canadian journal of physiology and pharmacology 20091001

• Punching holes in an enzyme.

  Chemistry & biology 20090925

• Ribocation transition state capture and rebound in human purine nucleoside phosphorylase.

  Chemistry & biology 20090925

• Steric and electrostatic effects at the C2 atom substituent influence replication and miscoding of the DNA deamination product deoxyxanthosine and analogs by DNA polymerases.

  Journal of molecular biology 20090918

• The novel inosine analogue INO-2002 exerts an anti-inflammatory effect in a murine model of acute lung injury.

  Shock (Augusta, Ga.) 20090901

• Widespread cleavage of A-to-I hyperediting substrates.

  RNA (New York, N.Y.) 20090901

• Inhibition of renal Na+-ATPase activity by inosine is mediated by A1 receptor-induced inhibition of the cAMP signaling pathway.

  Archives of biochemistry and biophysics 20090901

• Tipping the balance: antagonism of PKR kinase and ADAR1 deaminase functions by virus gene products.

  Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20090901

• [Living-related donor kidney transplantation in 158 patients].

  Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20090901

• Release of adenosine and ATP during ischemia and epilepsy.

  Current neuropharmacology 20090901

• The role of adenosine in Alzheimer's disease.

  Current neuropharmacology 20090901

• Adenosine neuromodulation and traumatic brain injury.

  Current neuropharmacology 20090901

• Adenosine and sleep.

  Current neuropharmacology 20090901

• Adenosine and the auditory system.

  Current neuropharmacology 20090901

• Matching active site and substrate structures for an RNA editing reaction.

  Journal of the American Chemical Society 20090826

• NMR spectroscopic elucidation of the B-Z transition of a DNA double helix induced by the Z alpha domain of human ADAR1.

  Journal of the American Chemical Society 20090819

• 8-Bromo-cyclic inosine diphosphoribose: towards a selective cyclic ADP-ribose agonist.

  The Biochemical journal 20090815

• Triazole inhibitors of Cryptosporidium parvum inosine 5'-monophosphate dehydrogenase.

  Journal of medicinal chemistry 20090813

• Identification of aspartic acid-203 in human thymidine phosphorylase as an important residue for both catalysis and non-competitive inhibition by the small molecule 'crystallization chaperone' 5'-O-tritylinosine (KIN59).

  Biochemical pharmacology 20090801

• Mechanism of thiol-supported arsenate reduction mediated by phosphorolytic-arsenolytic enzymes: I. The role of arsenolysis.

  Toxicological sciences : an official journal of the Society of Toxicology 20090801

• Mechanism of thiol-supported arsenate reduction mediated by phosphorolytic-arsenolytic enzymes: II. Enzymatic formation of arsenylated products susceptible for reduction to arsenite by thiols.

  Toxicological sciences : an official journal of the Society of Toxicology 20090801

• A fast capillary electrophoresis method for separation and quantification of modified nucleosides in urinary samples.

  Analytical chemistry 20090801

• Legionella pneumophila in rainwater on roads.

  Emerging infectious diseases 20090801

• African swine fever virus AP endonuclease is a redox-sensitive enzyme that repairs alkylating and oxidative damage to DNA.

  Virology 20090720

• TaqMan-based, real-time quantitative polymerase chain reaction method for RNA editing analysis.

  Analytical biochemistry 20090715

• ENDOR spectroscopy shows that guanine N1 binds to [4Fe-4S] cluster II of the S-adenosylmethionine-dependent enzyme MoaA: mechanistic implications.

  Journal of the American Chemical Society 20090708

• Antithetical effects of corticosterone and dibutyryl cAMP on adenosine deaminase in the gastrointestinal tract of chicken during postnatal development.

  Molecular and cellular biochemistry 20090701

• Increase of uric acid and purine compounds in biological fluids of multiple sclerosis patients.

  Clinical biochemistry 20090701

• Identification of the chloroplast adenosine-to-inosine tRNA editing enzyme.

  RNA (New York, N.Y.) 20090701

• Synthesis and anti-Hantaan virus activity of N(1)-3-fluorophenyl-inosine.

  Antiviral research 20090701

• Ultraviolet and tandem mass spectrometry for simultaneous quantification of 21 pivotal metabolites in plasma from patients with diabetic nephropathy.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090701

• Arabidopsis tRNA adenosine deaminase arginine edits the wobble nucleotide of chloroplast tRNAArg(ACG) and is essential for efficient chloroplast translation.

  The Plant cell 20090701

• Inosine alters gene expression and axonal projections in neurons contralateral to a cortical infarct and improves skilled use of the impaired limb.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20090624

• Altered enthalpy-entropy compensation in picomolar transition state analogues of human purine nucleoside phosphorylase.

  Biochemistry 20090616

• Kinetic analysis of base-pairing preference for nucleotide incorporation opposite template pyrimidines by human DNA polymerase iota.

  Journal of molecular biology 20090605

• Adenosine deaminase-adenosine pathway in hemolysis-associated pulmonary hypertension.

  Medical hypotheses 20090601

• Adenosine deamination to inosine in isolated basolateral membrane from kidney proximal tubule: implications for modulation of the membrane-associated protein kinase A.

  Archives of biochemistry and biophysics 20090601

• Improved assay for the nonradioactive determination of inosine 5'-monophosphate dehydrogenase activity in peripheral blood mononuclear cells.

  Therapeutic drug monitoring 20090601

• Protective effects of inosine on urinary bladder function in rats with partial bladder outlet obstruction.

  Urology 20090601

• The application of the phosphoramidate ProTide approach confers micromolar potency against hepatitis C virus on inactive agent 4'-azidoinosine: kinase bypass on a dual base/sugar modified nucleoside.

  Bioorganic & medicinal chemistry letters 20090601

• Analysis of urinary nucleosides as helper tumor markers in hepatocellular carcinoma diagnosis.

  Rapid communications in mass spectrometry : RCM 20090601

• Large-scale mRNA sequencing determines global regulation of RNA editing during brain development.

  Genome research 20090601

• The treatment of multiple sclerosis with inosine.

  Journal of alternative and complementary medicine (New York, N.Y.) 20090601

• T-705 (favipiravir) and related compounds: Novel broad-spectrum inhibitors of RNA viral infections.

  Antiviral research 20090601

• Borrelia burgdorferi bb0426 encodes a 2'-deoxyribosyltransferase that plays a central role in purine salvage.

  Molecular microbiology 20090601

• The treatment of multiple sclerosis with inosine.

  Journal of alternative and complementary medicine (New York, N.Y.) 20090601

• Adenosine and adenosine receptors: Newer therapeutic perspective.

  Indian journal of pharmacology 20090601

• Separation and identification of purine nucleosides in the urine of patients with malignant cancer by reverse phase liquid chromatography/electrospray tandem mass spectrometry.

  Journal of mass spectrometry : JMS 20090501

• Enzymatic properties of futalosine hydrolase, an enzyme essential to a newly identified menaquinone biosynthetic pathway.

  Bioscience, biotechnology, and biochemistry 20090501

• Comparative genomic characterization of Francisella tularensis strains belonging to low and high virulence subspecies.

  PLoS pathogens 20090501

• Studies on the glycosylation of pyrrolo[2,3-d] pyrimidines with 1-O-acetyl-2,3,5-tri-O-benzoyl-beta-D-ribofuranose: the formation of regioisomers during toyocamycin and 7-deazainosine syntheses.

  Nucleosides, nucleotides & nucleic acids 20090501

• Hexosamine biosynthesis pathway flux contributes to insulin resistance via altering membrane phosphatidylinositol 4,5-bisphosphate and cortical filamentous actin.

  Endocrinology 20090401

• Cyclic ADP-ribose links metabolism to multiple fission in the dinoflagellate Crypthecodinium cohnii.

  Cell calcium 20090401

• The purine nucleosides adenosine and guanosine delay axonal degeneration in vitro.

  Journal of neurochemistry 20090401

• Innovative electrochemical approach for an early detection of microRNAs.

  Analytical chemistry 20090401

• Membrane transport mechanisms of mizoribine in the rat intestine and human epithelial LS180 cells.

  Biological & pharmaceutical bulletin 20090401

• Rational drug correction of systemic inflammatory response syndrome in severe experimental heart failure.

  Bulletin of experimental biology and medicine 20090401

• A regulatory role of the Bateman domain of IMP dehydrogenase in adenylate nucleotide biosynthesis.

  The Journal of biological chemistry 20090320

• Quantitative analysis of RNA solvent accessibility by N-silylation of guanosine.

  Biochemistry 20090317

• Synthesis and antiviral evaluation of thieno[3,4-d]pyrimidine C-nucleoside analogues of 2',3'-dideoxy- and 2',3'-dideoxy-2',3'-didehydro-adenosine and -inosine.

  Bioorganic & medicinal chemistry 20090315

• Development of selective agonists and antagonists of P2Y receptors.

  Purinergic signalling 20090301

• Allosteric modulation of adenosine receptors.

  Purinergic signalling 20090301

• 3-Hydrogenkwadaphnine, a novel diterpene ester from Dendrostellera lessertii, its role in differentiation and apoptosis of KG1 cells.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20090301

• Effects of inosine on response to in vitro hypoxia in absence of substrate on bladder dysfunction in adult rats.

  Urology 20090301

• Biochemical characterization and homology modeling of a purine-specific ribonucleoside hydrolase from the archaeon Sulfolobus solfataricus: insights into mechanisms of protein stabilization.

  Archives of biochemistry and biophysics 20090301

• Influence of Ecto-nucleoside triphosphate diphosphohydrolase activity on Trypanosoma cruzi infectivity and virulence.

  PLoS neglected tropical diseases 20090301

• Uridine-ribohydrolase is a key regulator in the uridine degradation pathway of Arabidopsis.

  The Plant cell 20090301

• O6-(benzotriazol-1-yl)inosine derivatives for C6 modification of purine nucleosides.

  Current protocols in nucleic acid chemistry 20090301

• Direct electrochemical genosensing for multiple point mutation detection of Mycobacterium tuberculosis during the development of rifampin resistance.

  Biosensors & bioelectronics 20090215

• Inhibitors of adenosine consuming parasites through polymer-assisted solution phase synthesis of lipophilic 5'-amido-5'-deoxyadenosine derivatives.

  Bioorganic & medicinal chemistry 20090215

• Oxidation and glycolytic cleavage of etheno and propano DNA base adducts.

  Biochemistry 20090203

• Isolation and characterization of a novel adenosine deaminase inhibitor, IADA-7, from Bacillus sp. J-89.

  Journal of enzyme inhibition and medicinal chemistry 20090201

• Reverse dissimilatory sulfite reductase as phylogenetic marker for a subgroup of sulfur-oxidizing prokaryotes.

  Environmental microbiology 20090201

• Correlations of six related purine metabolites and diabetic nephropathy in Chinese type 2 diabetic patients.

  Clinical biochemistry 20090201

• Simian T-lymphotropic virus diversity among nonhuman primates, Cameroon.

  Emerging infectious diseases 20090201

• Purines and oxypurines in myocardial ischemia.

  Saudi medical journal 20090201

• A genome-scale metabolic reconstruction of Mycoplasma genitalium, iPS189.

  PLoS computational biology 20090201

• Synthesis and evaluation of an RNA editing substrate bearing 2'-deoxy-2'-mercaptoadenosine.

  Nucleosides, nucleotides & nucleic acids 20090201

• Protection of mice against X-ray injuries by the post-irradiation administration of guanosine and inosine.

  International journal of radiation biology 20090201

• Cloning and pharmacological characterization of a novel gene encoding human nucleoside transporter 1 (hNT1) from a human breast cancer cDNA library.

  Life sciences 20090102

• Inosine 5'-monophosphate dehydrogenase.

  Advances in enzymology and related areas of molecular biology 20090101

• Evidence of a new phosphoryl transfer system in nucleotide metabolism.

  The FEBS journal 20090101

• Transformation and action of extracellular NAD+ in perfused rat and mouse livers.

  Acta pharmacologica Sinica 20090101

• A new function for the RNA-editing enzyme ADAR1.

  Nature immunology 20090101

• Novel exon of mammalian ADAR2 extends open reading frame.

  PloS one 20090101

• The fascinating world of RNA interference.

  International journal of biological sciences 20090101

• Analysis on relationship between extreme pathways and correlated reaction sets.

  BMC bioinformatics 20090101

• Use of high-density tiling microarrays to identify mutations globally and elucidate mechanisms of drug resistance in Plasmodium falciparum.

  Genome biology 20090101

• Long-term surveillance of sulfate-reducing bacteria in highly saline industrial wastewater evaporation ponds.

  Saline systems 20090101

• Genome sequence of the pathogenic intestinal spirochete brachyspira hyodysenteriae reveals adaptations to its lifestyle in the porcine large intestine.

  PloS one 20090101

• Neuroprotective mechanisms of puerarin in middle cerebral artery occlusion-induced brain infarction in rats.

  Journal of biomedical science 20090101

• Filling kinetic gaps: dynamic modeling of metabolism where detailed kinetic information is lacking.

  PloS one 20090101

• ADAR1 and ADAR2 expression and editing activity during forebrain development.

  Developmental neuroscience 20090101

• Controversies surrounding human papilloma virus infection, head & neck vs oral cancer, implications for prophylaxis and treatment.

  Head & neck oncology 20090101

• Prediction of breast cancer by profiling of urinary RNA metabolites using Support Vector Machine-based feature selection.

  BMC cancer 20090101

• Constraint-based analysis of metabolic capacity of Salmonella typhimurium during host-pathogen interaction.

  BMC systems biology 20090101

• Bioinformatics analysis suggests base modifications of tRNAs and miRNAs in Arabidopsis thaliana.

  BMC genomics 20090101

• Quantitation of DNA methylation by melt curve analysis.

  BMC cancer 20090101

• Molecular profiles of Quadriceps muscle in myostatin-null mice reveal PI3K and apoptotic pathways as myostatin targets.

  BMC genomics 20090101

• Using in silico models to simulate dual perturbation experiments: procedure development and interpretation of outcomes.

  BMC systems biology 20090101

• The necrotic signal induced by mycophenolic acid overcomes apoptosis-resistance in tumor cells.

  PloS one 20090101

• Development of a real-time reverse-transcription PCR for the detection and simultaneous pathotyping of Newcastle disease virus isolates using a novel probe.

  Archives of virology 20090101

• Gene organization and sequence analyses of transfer RNA genes in Trypanosomatid parasites.

  BMC genomics 20090101

• Dynamic regulation of RNA editing of ion channels and receptors in the mammalian nervous system.

  Molecular brain 20090101

• Interfering ribonucleic acids that suppress expression of multiple unrelated genes.

  BMC biotechnology 20090101

• Conservation of structure and activity in Plasmodium purine nucleoside phosphorylases.

  BMC structural biology 20090101

• A conserved ethylene biosynthesis enzyme leads to andromonoecy in two cucumis species.

  PloS one 20090101

• Purine nucleoside phosphorylase deficiency in two unrelated Saudi patients.

  Annals of Saudi medicine 20090101

• Integrin alpha6Bbeta4 inhibits colon cancer cell proliferation and c-Myc activity.

  BMC cancer 20090101

• Surviving the cold: molecular analyses of insect cryoprotective dehydration in the Arctic springtail Megaphorura arctica (Tullberg).

  BMC genomics 20090101

• Mycophenolate pharmacokinetics and pharmacodynamics in belatacept treated renal allograft recipients - a pilot study.

  Journal of translational medicine 20090101

• Bacillus cereus spores release alanine that synergizes with inosine to promote germination.

  PloS one 20090101

• Positive selection at codon 38 of the human KCNE1 (= minK) gene and sporadic absence of 38Ser-coding mRNAs in Gly38Ser heterozygotes.

  BMC evolutionary biology 20090101

• Regulation of MicroRNA Biogenesis: A miRiad of mechanisms.

  Cell communication and signaling : CCS 20090101

• Genetic and molecular basis of individual differences in human umami taste perception.

  PloS one 20090101

• Equilibrium and kinetic investigations of the interaction of model platinum(II) complex with DNA constituents in reference to the antitumour activity: complex-formation reactions of [Pd(N,N-diethylethylenediamine)(H2O)2]2+ with ligands of biological significance and displacement reactions of DNA constituents.

  Bioinorganic chemistry and applications 20090101

• Pegademase bovine (PEG-ADA) for the treatment of infants and children with severe combined immunodeficiency (SCID).

  Biologics : targets & therapy 20090101

• Effect of insulin and glucose on adenosine metabolizing enzymes in human B lymphocytes.

  Acta biochimica Polonica 20090101

• Mycophenolic acid formulations in adult renal transplantation - update on efficacy and tolerability.

  Therapeutics and clinical risk management 20090101

• In vitro pharmacology of inosine, with special reference to possible interactions with capsaicin-sensitive mechanisms and inflammatory mediators.

  Methods and findings in experimental and clinical pharmacology 20090101

• miRExpress: analyzing high-throughput sequencing data for profiling microRNA expression.

  BMC bioinformatics 20090101

• A novel mutation in the ADA gene causing severe combined immunodeficiency in an Arab patient: a case report.

  Journal of medical case reports 20090101

• Nme protein family evolutionary history, a vertebrate perspective.

  BMC evolutionary biology 20090101

• Genetic characterization of the complete genome of a highly divergent simian T-lymphotropic virus (STLV) type 3 from a wild Cercopithecus mona monkey.

  Retrovirology 20090101

• Inferring branching pathways in genome-scale metabolic networks.

  BMC systems biology 20090101

• Antiarrhythmic and arrhythmogenic action of inosine in experimental ventricular tachyarrhythmias.

  Archivos de cardiologia de Mexico 20090101

• Glycine Receptors Caught between Genome and Proteome - Functional Implications of RNA Editing and Splicing.

  Frontiers in molecular neuroscience 20090101

• Evidence for ADAR-induced hypermutation of the Drosophila sigma virus (Rhabdoviridae).

  BMC genetics 20090101

• Human liver rate-limiting enzymes influence metabolic flux via branch points and inhibitors.

  BMC genomics 20090101

• Potential biological role of poly (ADP-ribose) polymerase (PARP) in male gametes.

  Reproductive biology and endocrinology : RB&E 20090101

• Feature selection and classification of MAQC-II breast cancer and multiple myeloma microarray gene expression data.

  PloS one 20090101

• RNA editing genes associated with extreme old age in humans and with lifespan in C. elegans.

  PloS one 20090101

• Phylogenetic analysis and temporal diversification of mosquitoes (Diptera: Culicidae) based on nuclear genes and morphology.

  BMC evolutionary biology 20090101

• Mizoribine: a new approach in the treatment of renal disease.

  Clinical & developmental immunology 20090101

• Disease-modifying agents in multiple sclerosis.

  Annals of Indian Academy of Neurology 20090101

• Cellular assessment of muscle in COPD: case studies of two males.

  International journal of general medicine 20090101

• Immunoregulation through IL-10 gene expression and the fate of cytotoxic T lymphocyte-mediated tumor immunotherapy.

  Indian journal of human genetics 20090101

• Coronary artery disease: a study on the joint role of birth weight, adenosine deaminase, and gender.

  Cardiology research and practice 20090101

• Adenosine-to-inosine RNA editing.

  Wiley interdisciplinary reviews. Systems biology and medicine 20090101

• Assessment of the Potential Role of Tryptophan as the Precursor of Serotonin and Melatonin for the Aged Sleep-wake Cycle and Immune Function: Streptopelia Risoria as a Model.

  International journal of tryptophan research : IJTR 20090101

• Contribution of Na+-independent nucleoside transport to ribavirin uptake in the rat intestine and human epithelial LS180 cells.

  European journal of pharmacology 20081228

• Characterization of ADAR1-mediated modulation of gene expression.

  Biochemical and biophysical research communications 20081205

• Hydrolytic cleavage of N6-substituted adenine derivatives by eukaryotic adenine and adenosine deaminases.

  Bioscience reports 20081201

• Inosine ameliorates the effects of hemin-induced oxidative stress in broilers.

  Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20081201

• Pharmacodynamics of mycophenolic acid in CD4+ cells: a single-dose study of IMPDH and purine nucleotide responses in healthy individuals.

  Therapeutic drug monitoring 20081201

• Differential selective constraints shaping codon usage pattern of housekeeping and tissue-specific homologous genes of rice and arabidopsis.

  DNA research : an international journal for rapid publication of reports on genes and genomes 20081201

• Effect of cardiovascular drugs on adenosine deaminase activity.

  Angiology 20081201

• Interpopulation variation frequency of human inosine 5'-monophosphate dehydrogenase type II (IMPDH2) genetic polymorphisms.

  Genetic testing 20081201

• Mycophenolic derivatives from Eupenicillium parvum.

  Journal of natural products 20081201

• A novel nucleoside kinase from Burkholderia thailandensis: a member of the phosphofructokinase B-type family of enzymes.

  The FEBS journal 20081201

• Dysregulated editing of serotonin 2C receptor mRNAs results in energy dissipation and loss of fat mass.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20081126

• Adenosine produced by neurons is metabolized to hypoxanthine by astrocytes.

  Journal of neuroscience research 20081115

• Antiproliferative effects of AVN944, a novel inosine 5-monophosphate dehydrogenase inhibitor, in prostate cancer cells.

  International journal of cancer 20081115

• Altered editing in cyclic nucleotide phosphodiesterase 8A1 gene transcripts of systemic lupus erythematosus T lymphocytes.

  Immunology 20081101

• Quantitative PCR measurements of the effects of introducing inosines into primers provides guidelines for improved degenerate primer design.

  Journal of virological methods 20081101

• Gene regulation by SINES and inosines: biological consequences of A-to-I editing of Alu element inverted repeats.

  Cell cycle (Georgetown, Tex.) 20081101

• L-theanine elicits an umami taste with inosine 5'-monophosphate.

  Bioscience, biotechnology, and biochemistry 20081101

• Estimation of adenosine and its major metabolites in brain tissues of rats using high-performance thin-layer chromatography-densitometry.

  Journal of chromatography. A 20081031

• ESI-MS characterization of a novel pyrrole-inosine nucleoside that interacts with guanine bases.

  Analytica chimica acta 20081003

• Diversity of spore germination in response to inosine and L-alanine and its interaction with NaCl and pH in the Bacillus cereus group.

  Journal of applied microbiology 20081001

• Overexpression, purification and characterization of functional calf purine nucleoside phosphorylase (PNP).

  Protein expression and purification 20081001

• Sulfasalazine blocks the development of tactile allodynia in diabetic rats.

  Diabetes 20081001

• Genetic evidence for the essential role of PfNT1 in the transport and utilization of xanthine, guanine, guanosine and adenine by Plasmodium falciparum.

  Molecular and biochemical parasitology 20081001

• Electroanalytical study of proflavine intercalation in 5-methyl or inosine-containing amplicons.

  Analytical and bioanalytical chemistry 20081001

• C. elegans and H. sapiens mRNAs with edited 3' UTRs are present on polysomes.

  RNA (New York, N.Y.) 20081001

• Development and validation of an RP-HPLC method for the estimation of adenosine and related purines in brain tissues of rats.

  Journal of separation science 20081001

• [An enzyme electrode biosensor for inosine determination].

  Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20081001

• Flavour formation in pork semimembranosus: Combination of pan-temperature and raw meat quality.

  Meat science 20081001

• Mathematical model of nucleotide regulation on airway epithelia. Implications for airway homeostasis.

  The Journal of biological chemistry 20080926

• Evidence for altered hippocampal volume and brain metabolites in workers occupationally exposed to lead: a study by magnetic resonance imaging and (1)H magnetic resonance spectroscopy.

  Toxicology letters 20080926

• Trans-splicing in C. elegans generates the negative RNAi regulator ERI-6/7.

  Nature 20080925

• Effects of sample preparation methods on the quantification of nucleosides in natural and cultured Cordyceps.

  Journal of pharmaceutical and biomedical analysis 20080910

• Astrocytes affect the profile of purines released from cultured cortical neurons.

  Journal of neuroscience research 20080901

• The novel inosine analogue, INO-2002, protects against diabetes development in multiple low-dose streptozotocin and non-obese diabetic mouse models of type I diabetes.

  The Journal of endocrinology 20080901

• Kinetic characterization of adenosine deaminase activity in zebrafish (Danio rerio) brain.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20080901

• Involvement of ERK/MAPK pathway in megakaryocytic differentiation of K562 cells induced by 3-hydrogenkwadaphnin.

  Toxicology in vitro : an international journal published in association with BIBRA 20080901

• Effect of Maillard reacted peptides on human salt taste and the amiloride-insensitive salt taste receptor (TRPV1t).

  Chemical senses 20080901

• NMR-based metabonomic investigations into the metabolic profile of the senescence-accelerated mouse.

  Journal of proteome research 20080901

• Top-down analysis of temporal hierarchy in biochemical reaction networks.

  PLoS computational biology 20080901

• Intronic Alus influence alternative splicing.

  PLoS genetics 20080901

• Capturing hammerhead ribozyme structures in action by modulating general base catalysis.

  PLoS biology 20080901

• Effect of nadcin on energy supply system and apoptosis in ischemia-reperfusion injury to the myocardium.

  Bulletin of experimental biology and medicine 20080901

• Determination of nucleotides in infant formula by ion-exchange liquid chromatography.

  Journal of agricultural and food chemistry 20080827

• High sensitivity to transmission of attenuation in the metal activating effect of platinum on sequential H-D exchange at the four C8 sites of inosines in tetrakis(inosine)platinum(II) chloride.

  Organic & biomolecular chemistry 20080821

• A kinetic alignment of orthologous inosine-5'-monophosphate dehydrogenases.

  Biochemistry 20080819

• Stem/progenitor cells in lung development, injury repair, and regeneration.

  Proceedings of the American Thoracic Society 20080815

• RNA editing in regulating gene expression in the brain.

  Biochimica et biophysica acta 20080801

• A-to-I RNA editing alters less-conserved residues of highly conserved coding regions: implications for dual functions in evolution.

  RNA (New York, N.Y.) 20080801

• p42/44 MAPK is an essential effector for purine nucleoside-mediated neuroprotection of hypoxic PC12 cells and primary cerebellar granule neurons.

  Molecular and cellular neurosciences 20080801

• Fine targeting of purine salvage in Cryptosporidium parasites.

  Trends in parasitology 20080801

• 7-Deaza-2'-deoxyinosine: a nucleoside showing ambiguous base-pairing properties against the four canonical DNA constituents.

  Acta crystallographica. Section C, Crystal structure communications 20080801

• An enzymatic atavist revealed in dual pathways for water activation.

  PLoS biology 20080801

• An enzymatic palimpsest.

  PLoS biology 20080801

• Simultaneous determination of adenosine and inosine using single-wall carbon nanotubes modified pyrolytic graphite electrode.

  Talanta 20080730

• Synthesis of an oligodeoxyribonucleotide adduct of mitomycin C by the postoligomerization method via a triamino mitosene.

  Journal of the American Chemical Society 20080723

• Heterogeneity and clinical significance of ETV1 translocations in human prostate cancer.

  British journal of cancer 20080722

• Therapeutic benefit derived from RNAi-mediated ablation of IMPDH1 transcripts in a murine model of autosomal dominant retinitis pigmentosa (RP10).

  Human molecular genetics 20080715

• Halicyclamine A, a marine spongean alkaloid as a lead for anti-tuberculosis agent.

  Bioorganic & medicinal chemistry 20080715

• Genotypic resistance testing in HIV by arrayed primer extension.

  Analytical and bioanalytical chemistry 20080701

• Distinct MAPK signaling pathways, p21 up-regulation and caspase-mediated p21 cleavage establishes the fate of U937 cells exposed to 3-hydrogenkwadaphnin: differentiation versus apoptosis.

  Toxicology and applied pharmacology 20080701

• Exposure to bioaerosols in poultry houses at different stages of fattening; use of real-time PCR for airborne bacterial quantification.

  The Annals of occupational hygiene 20080701

• RNA editing of the serotonin 5HT2C receptor and its effects on cell signalling, pharmacology and brain function.

  Pharmacology & therapeutics 20080701

• Synthetic utility of an isolable nucleoside phosphonium salt.

  Organic letters 20080605

• A quick method for the quantitative analysis of mixtures. 1. Powder X-ray diffraction.

  Journal of pharmaceutical sciences 20080601

• HIF-1 alpha is an essential effector for purine nucleoside-mediated neuroprotection against hypoxia in PC12 cells and primary cerebellar granule neurons.

  Journal of neurochemistry 20080601

• Assessment of nerve stimulation-induced release of purines from mouse kidneys by tandem mass spectrometry.

  The Journal of pharmacology and experimental therapeutics 20080601

• Purinergic signaling microenvironments: An introduction.

  Purinergic signalling 20080601

• Cellular pharmacokinetics of telavancin, a novel lipoglycopeptide antibiotic, and analysis of lysosomal changes in cultured eukaryotic cells (J774 mouse macrophages and rat embryonic fibroblasts).

  The Journal of antimicrobial chemotherapy 20080601

• Inosine and equilibrative nucleoside transporter 2 contribute to hypoxic preconditioning in the murine cardiomyocyte HL-1 cell line.

  American journal of physiology. Heart and circulatory physiology 20080601

• Nucleoside composition of Heloderma venoms.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20080601

• Specificity of ADAR-mediated RNA editing in newly identified targets.

  RNA (New York, N.Y.) 20080601

• Co-regulation of yeast purine and phosphate pathways in response to adenylic nucleotide variations.

  Molecular microbiology 20080601

• Interactions of nucleosides with CrO(4) (2-) and Cr(3+) as studied by electrospray ionization mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20080601

• Gene expression is reduced in trans by inosine-containing dsRNA.

  Biochemical Society transactions 20080601

• Metabonomics in cancer diagnosis: mass spectrometry-based profiling of urinary nucleosides from breast cancer patients.

  Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20080601

• Downregulation of the Escherichia coli guaB promoter by FIS.

  Microbiology (Reading, England) 20080601

• A kinetic study of the rat liver adenosine kinase reverse reaction.

  Nucleosides, nucleotides & nucleic acids 20080601

• Water-soluble precursors of beef flavour. Part II: Effect of post-mortem conditioning.

  Meat science 20080601

• Characterization of intestinal absorption of mizoribine mediated by concentrative nucleoside transporters in rats.

  European journal of pharmacology 20080531

• A novel polymer supported approach to nucleoside modification.

  The Journal of organic chemistry 20080516

• Insights into DNA binding of ruthenium arene complexes: role of hydrogen bonding and pi stacking.

  Inorganic chemistry 20080505

• Adenosine increases calcium sensitivity via receptor-independent activation of the p38/MK2 pathway in mesenteric arteries.

  Acta physiologica (Oxford, England) 20080501

• Purine nucleoside phosphorylase from Pseudoalteromonas sp. Bsi590: molecular cloning, gene expression and characterization of the recombinant protein.

  Extremophiles : life under extreme conditions 20080501

• Molecular modeling and dynamics simulations of PNP from Streptococcus agalactiae.

  Bioorganic & medicinal chemistry 20080501

• Structure of the exosporium and sublayers of spores of the Bacillus cereus family revealed by electron crystallography.

  Molecular microbiology 20080501

• The role of a purine-specific nucleoside hydrolase in spore germination of Bacillus thuringiensis.

  Microbiology (Reading, England) 20080501

• 7-deazainosine derivatives: synthesis and characterization of 7- and 7,8-substituted pyrrolo [2,3-d]pyrimidine ribonucleosides.

  Nucleosides, nucleotides & nucleic acids 20080501

• Shockwave lithotripsy and protective role of inosine: early and late evaluation in an experimental model.

  Journal of endourology 20080501

• Binding and catalytic contributions to site recognition by flp recombinase.

  The Journal of biological chemistry 20080425

• Retinal isoforms of inosine 5'-monophosphate dehydrogenase type 1 are poor nucleic acid binding proteins.

  Archives of biochemistry and biophysics 20080415

• Novel azaphilones, kasanosins A and B, which are specific inhibitors of eukaryotic DNA polymerases beta and lambda from Talaromyces sp.

  Bioorganic & medicinal chemistry 20080415

• Structural basis for substrate specificity in group I nucleoside hydrolases.

  Biochemistry 20080415

• Inosylyl(3'-->5')inosine (IpI-). Acid-base and metal ion-binding properties of a dinucleoside monophosphate in aqueous solution.

  Inorganic chemistry 20080407

• Miscoding properties of 2'-deoxyinosine, a nitric oxide-derived DNA Adduct, during translesion synthesis catalyzed by human DNA polymerases.

  Journal of molecular biology 20080404

• Exogenous nucleosides accelerate differentiation of rat intestinal epithelial cells.

  The British journal of nutrition 20080401

• Taste sensitivity for monosodium glutamate and an increased liking of dietary protein.

  The British journal of nutrition 20080401

• TGF-beta signaling promotes survival and repair in rat alveolar epithelial type 2 cells during recovery after hyperoxic injury.

  American journal of physiology. Lung cellular and molecular physiology 20080401

• The CBS subdomain of inosine 5'-monophosphate dehydrogenase regulates purine nucleotide turnover.

  Molecular microbiology 20080401

• Cyclic AMP in rat ileum: evidence for the presence of an extracellular cyclic AMP-adenosine pathway.

  Gastroenterology 20080401

• A study on the inhibition of adenosine deaminase.

  Journal of enzyme inhibition and medicinal chemistry 20080401

• Specificity of stimulation of human 8-oxoguanine-DNA glycosylase by AP endonuclease.

  Biochemical and biophysical research communications 20080328

• Retraction notice to 'Validation and application of a high-performance liquid chromatographic-based assay for determination of the inosine 5'-monophosphate dehydrogenase activity in erythrocytes.' [J. Chromatogr. B 842 (2006) 1-7].

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080315

• Kinetics of nucleoside uptake by the basolateral side of the sheep choroid plexus epithelium perfused in situ.

  Experimental physiology 20080301

• Synthesis and characterization of DNA containing an N1-2'-deoxyinosine-ethyl-N3-thymidine interstrand cross-link: a structural mimic of the cross-link formed by 1,3-bis-(2-chloroethyl)-1-nitrosourea.

  Chemical research in toxicology 20080301

• Implication of S-adenosylhomocysteine hydrolase in inhibition of TNF-alpha- and IL-1beta-induced expression of inflammatory mediators by AICAR in RPE cells.

  Investigative ophthalmology & visual science 20080301

• Cyclic ADP-ribose mediates formyl methionyl leucyl phenylalanine (fMLP)-induced intracellular Ca(2+) rise and migration of human neutrophils.

  Journal of pharmacological sciences 20080301

• Internalization and desensitization of adenosine receptors.

  Purinergic signalling 20080301

• Application of heme oxygenase-1, carbon monoxide and biliverdin for the prevention of intestinal ischemia/reperfusion injury.

  Journal of clinical biochemistry and nutrition 20080301

• [The gerA operon is required for spore germination in Bacillus thuringiensis].

  Wei sheng wu xue bao = Acta microbiologica Sinica 20080301

• Adenosine kinase mediates high affinity adenosine salvage in Trypanosoma brucei.

  The Journal of biological chemistry 20080227

• Transition state structure of E. coli tRNA-specific adenosine deaminase.

  Journal of the American Chemical Society 20080227

• Transition-state interactions revealed in purine nucleoside phosphorylase by binding isotope effects.

  Journal of the American Chemical Society 20080220

• Unusual deoxygenation and reactivity studies related to O6-(benzotriazol-1-yl)inosine derivatives.

  The Journal of organic chemistry 20080215

• Inhibition of adenosine deaminase by analogues of adenosine and inosine, incorporating a common heterocyclic base, 4(7)-amino-6(5)H-imidazo[4,5-d]pyridazin-7(4)one.

  Journal of medicinal chemistry 20080214

• Kinetic studies on the reactions of [Pd(dach)(X-Y)] complexes with some DNA constituents.

  Dalton transactions (Cambridge, England : 2003) 20080214

• Distribution of nucleosides and nucleobases in edible fungi.

  Journal of agricultural and food chemistry 20080213

• Role of ionization of the phosphate cosubstrate on phosphorolysis by purine nucleoside phosphorylase (PNP) of bacterial (E. coli) and mammalian (human) origin.

  European biophysics journal : EBJ 20080201

• Removal of deoxyinosine from the Escherichia coli chromosome as studied by oligonucleotide transformation.

  DNA repair 20080201

• Influence of the sporulation temperature on the impact of the nutrients inosine and l-alanine on Bacillus cereus spore germination.

  Food microbiology 20080201

• A-to-I editing sites are a genomically encoded G: implications for the evolutionary significance and identification of novel editing sites.

  RNA (New York, N.Y.) 20080201

• Structural requirements for the activation of Escherichia coli CTP synthase by the allosteric effector GTP are stringent, but requirements for inhibition are lax.

  The Journal of biological chemistry 20080125

• Structures of dimeric nonstandard nucleotide triphosphate pyrophosphatase from Pyrococcus horikoshii OT3: functional significance of interprotomer conformational changes.

  Journal of molecular biology 20080125

• Immunomodulatory effect of the purine nucleoside inosine following spinal cord contusion injury in rat.

  Spinal cord 20080101

• Transformation products of extracellular NAD(+) in the rat liver: kinetics of formation and metabolic action.

  Molecular and cellular biochemistry 20080101

• Mutational inhibition of ligation in the hairpin ribozyme: substitutions of conserved nucleobases A9 and A10 destabilize tertiary structure and selectively promote cleavage.

  RNA (New York, N.Y.) 20080101

• Codon usage suggests that translational selection has a major impact on protein expression in trypanosomatids.

  BMC genomics 20080101

• Pleiotropic phenotypes of a Yersinia enterocolitica flhD mutant include reduced lethality in a chicken embryo model.

  BMC microbiology 20080101

• Universal primers that amplify RNA from all three flavivirus subgroups.

  Virology journal 20080101

• Role of uric acid in multiple sclerosis.

  Current topics in microbiology and immunology 20080101

• Analysis of non-TIR NBS-LRR resistance gene analogs in Musa acuminata Colla: isolation, RFLP marker development, and physical mapping.

  BMC plant biology 20080101

• The effects of creatine pyruvate and creatine citrate on performance during high intensity exercise.

  Journal of the International Society of Sports Nutrition 20080101

• Sex differences in adenosine deaminase activity of stroke patients.

  Clinical chemistry and laboratory medicine 20080101

• Alterations in vasomotor control of coronary resistance vessels in remodelled myocardium of swine with a recent myocardial infarction.

  Medical & biological engineering & computing 20080101

• Inhibition of iron-catalyzed oxidations by attainable uric acid and ascorbic acid levels: therapeutic implications for Alzheimer's disease and late cognitive impairment.

  Gerontology 20080101

• Is plant mitochondrial RNA editing a source of phylogenetic incongruence? An answer from in silico and in vivo data sets.

  BMC bioinformatics 20080101

• High-throughput synthesis of HepDirect prodrugs of nucleoside monophosphates.

  Journal of combinatorial chemistry 20080101

• Exogenous nitric oxide requires an endothelial glycocalyx to prevent postischemic coronary vascular leak in guinea pig hearts.

  Critical care (London, England) 20080101

• 'Systems toxicology' approach identifies coordinated metabolic responses to copper in a terrestrial non-model invertebrate, the earthworm Lumbricus rubellus.

  BMC biology 20080101

• Metabolism of nicotinamide, adenine and inosine in developing microspore-derived canola (Brassica napus) embryos.

  Plant physiology and biochemistry : PPB 20080101

• The AID/APOBEC family of nucleic acid mutators.

  Genome biology 20080101

• IMP dehydrogenase basal activity in MOLT-4 human leukaemia cells is altered by mycophenolic acid and 6-thioguanosine.

  Scandinavian journal of clinical and laboratory investigation 20080101

• A broad spectrum, one-step reverse-transcription PCR amplification of the neuraminidase gene from multiple subtypes of influenza A virus.

  Virology journal 20080101

• Global regulation of nucleotide biosynthetic genes by c-Myc.

  PloS one 20080101

• The cost of wobble translation in fungal mitochondrial genomes: integration of two traditional hypotheses.

  BMC evolutionary biology 20080101

• Adenosine deaminase activity is a sensitive marker for the diagnosis of tuberculous pleuritis in patients with very low CD4 counts.

  PloS one 20080101

• Evolutionary patterns in the sequence and structure of transfer RNA: a window into early translation and the genetic code.

  PloS one 20080101

• A-to-I RNA editing and cancer: from pathology to basic science.

  RNA biology 20080101

• The genetics of feto-placental development: a study of acid phosphatase locus 1 and adenosine deaminase polymorphisms in a consecutive series of newborn infants.

  Reproductive biology and endocrinology : RB&E 20080101

• Self-Avoiding Molecular Recognition Systems (SAMRS).

  Nucleic acids symposium series (2004) 20080101

• Structure-activity relationship of an antisense oligonucleotide-two Cu(II) complex conjugate as an artificial ribonuclease.

  Nucleic acids symposium series (2004) 20080101

• Azide-alkyne 'click' reaction performed on oligonucleotides with the universal nucleoside 7-octadiynyl-7-deaza-2'-deoxyinosine.

  Nucleic acids symposium series (2004) 20080101

• Synthesis of N-1-alkyl analogues of cyclic inosine diphosphate ribose (cIDPR) by a new solid phase approach.

  Nucleic acids symposium series (2004) 20080101

• Model-driven analysis of experimentally determined growth phenotypes for 465 yeast gene deletion mutants under 16 different conditions.

  Genome biology 20080101

• Bench-to-bedside review: adenosine receptors--promising targets in acute lung injury?

  Critical care (London, England) 20080101

• RNomics and Modomics in the halophilic archaea Haloferax volcanii: identification of RNA modification genes.

  BMC genomics 20080101

• Systemic multicompartmental effects of the gut microbiome on mouse metabolic phenotypes.

  Molecular systems biology 20080101

• Drugs and herbs given to prevent hepatotoxicity of tuberculosis therapy: systematic review of ingredients and evaluation studies.

  BMC public health 20080101

• Dramatic down-regulation of oxidoreductases in human hepatocellular carcinoma hepG2 cells: proteomics and gene ontology unveiling new frontiers in cancer enzymology.

  Proteome science 20080101

• Newly identified ADAR-mediated A-to-I editing positions as a tool for ALS research.

  RNA biology 20080101

• Comparing methods of detection and quantitation of RNA editing of rat glycine receptor alpha3.

  International journal of biological sciences 20080101

• Application of capillary electrophoresis for the identification of Atlantic salmon and rainbow trout under raw and heat treatment.

  Journal of capillary electrophoresis and microchip technology 20080101

• Clostridium perfringens delta toxin is sequence related to beta toxin, NetB, and Staphylococcus pore-forming toxins, but shows functional differences.

  PloS one 20080101

• FRET imaging of hemoglobin concentration in Plasmodium falciparum-infected red cells.

  PloS one 20080101

• [Basic and metabolic therapy of hypertensive disease in pregnant women].

  Klinicheskaia meditsina 20080101

• Flexible modulation of agonist efficacy at the human A3 adenosine receptor by the imidazoquinoline allosteric enhancer LUF6000.

  BMC pharmacology 20080101

• Chromosomal inversions between human and chimpanzee lineages caused by retrotransposons.

  PloS one 20080101

• RIG-I and dsRNA-induced IFNbeta activation.

  PloS one 20080101

• The effect of preservation solutions UW and EC on purine concentration in rat kidney.

  Annales Academiae Medicae Stetinensis 20080101

• A Solanum lycopersicum x Solanum pimpinellifolium linkage map of tomato displaying genomic locations of R-genes, RGAs, and candidate resistance/defense-response ESTs.

  International journal of plant genomics 20080101

• Purine release: a protective signaling mechanism of the mitochondrial permeability transition pore in ischemia.

  Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20080101

• Formulation of New Algorithmics for miRNAs.

  The open virology journal 20080101

• RNA processing and mRNA surveillance in monogenic diabetes.

  Gene regulation and systems biology 20080101

• Management of erythema nodosum leprosum by mycophenolate mofetil.

  Indian journal of dermatology 20080101

• Allelic variation of the Tas1r3 taste receptor gene selectively affects taste responses to sweeteners: evidence from 129.B6-Tas1r3 congenic mice.

  Physiological genomics 20071219

• Intense exercise increases adenosine concentrations in rat brain: implications for a homeostatic sleep drive.

  Neuroscience 20071219

• Adenosine enhances long term the contractile response to angiotensin II in afferent arterioles.

  American journal of physiology. Regulatory, integrative and comparative physiology 20071201

• Molecular modeling study on the enantioselective binding of S- and R-ofloxacin to various DNA sequences.

  Journal of biomolecular structure & dynamics 20071201

• Effects of fructose-1,6-diphosphate on endo- and myocardial purine metabolism during coronary artery bypass grafting surgery.

  The Journal of cardiovascular surgery 20071201

• Molecular dynamics simulations and their application to four-stranded DNA.

  Methods (San Diego, Calif.) 20071201

• Human 5-HT(4) and 5-HT(7) receptor splice variants: are they important?

  Current neuropharmacology 20071201

• Wobble inosine tRNA modification is essential to cell cycle progression in G(1)/S and G(2)/M transitions in fission yeast.

  The Journal of biological chemistry 20071116

• [Evaluation for two-year highly active antiretroviral therapy in Chinese HIV-1 infection patients].

  Zhonghua yi xue za zhi 20071113

• Adenosine deaminase-related genes: molecular identification, tissue expression pattern and truncated alternative splice isoform in adult zebrafish (Danio rerio).

  Life sciences 20071110

• Inosine-containing dsRNA binds a stress-granule-like complex and downregulates gene expression in trans.

  Molecular cell 20071109

• Identification and characterization of new impurity in didanosine.

  Journal of pharmaceutical and biomedical analysis 20071105

• Extracellular interconversion of nucleotides reveals an ecto-adenylate kinase activity in the rat hippocampus.

  Neurochemical research 20071101

• Release of ATP in the central nervous system during systemic inflammation: real-time measurement in the hypothalamus of conscious rabbits.

  The Journal of physiology 20071101

• Altered adenosine-to-inosine RNA editing in human cancer.

  Genome research 20071101

• Genetic basis for retention of a critical virulence plasmid of Borrelia burgdorferi.

  Molecular microbiology 20071101

• RNA analysis by MEKC with LIF detection.

  Electrophoresis 20071101

• Examination of the mechanism and energetic contribution of leaving group activation in the purine-specific nucleoside hydrolase from Trypanosoma vivax.

  Biochimica et biophysica acta 20071101

• Clastogenic factors in the plasma of patients with hepatitis C: their possible role at the origin of hepatocarcinoma.

  Cancer genetics and cytogenetics 20071101

• Anopheles gambiae purine nucleoside phosphorylase: catalysis, structure, and inhibition.

  Biochemistry 20071030

• Efficient syntheses of 5'-deoxy-5'-fluoroguanosine and -inosine.

  The Journal of organic chemistry 20071026

• Solid-phase synthesis of symmetrical 5',5'-dinucleoside mono-, di-, tri-, and tetraphosphodiesters.

  Organic letters 20071025

• A-to-I editing challenger or ally to the microRNA process.

  Biochimie 20071001

• Mammalian mismatches in nucleotide metabolism: implications for xenotransplantation.

  Molecular and cellular biochemistry 20071001

• Fast simultaneous determination of 14 nucleosides and nucleobases in cultured Cordyceps using ultra-performance liquid chromatography.

  Talanta 20070915

• Adenosine deaminase 1 and concentrative nucleoside transporters 2 and 3 regulate adenosine on the apical surface of human airway epithelia: implications for inflammatory lung diseases.

  Biochemistry 20070911

• Mizoribine corrects defective nephrin biogenesis by restoring intracellular energy balance.

  Journal of the American Society of Nephrology : JASN 20070901

• Identification and functional analysis of variants in the human concentrative nucleoside transporter 2, hCNT2 (SLC28A2) in Chinese, Malays and Indians.

  Pharmacogenetics and genomics 20070901

• Role of pulmonary adenosine during hypoxia: extracellular generation, signaling and metabolism by surface adenosine deaminase/CD26.

  Expert opinion on biological therapy 20070901

• [Clinical experiment of cytokines induced killer cells for treatment of benzene poisoning].

  Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20070901

• The role of ATP and adenosine in the brain under normoxic and ischemic conditions.

  Purinergic signalling 20070901

• New insights into purinergic receptor signaling in neuronal differentiation, neuroprotection, and brain disorders.

  Purinergic signalling 20070901

• [(3)H]Adenine is a suitable radioligand for the labeling of G protein-coupled adenine receptors but shows high affinity to bacterial contaminations in buffer solutions.

  Purinergic signalling 20070901

• Allosteric theory: taking therapeutic advantage of the malleable nature of GPCRs.

  Current neuropharmacology 20070901

• Structure-based activity prediction for an enzyme of unknown function.

  Nature 20070816

• Effects of age-dependent membrane transport changes on the homeostasis of senescent human red blood cells.

  Blood 20070815

• Hyperphagia-mediated obesity in transgenic mice misexpressing the RNA-editing enzyme ADAR2.

  The Journal of biological chemistry 20070803

• Exogenous nucleic acids and nucleotides are efficiently hydrolysed and taken up as nucleosides by intestinal explants from suckling piglets.

  The British journal of nutrition 20070801

• Editing of AMPA and serotonin 2C receptors in individual central neurons, controlling wakefulness.

  Cellular and molecular neurobiology 20070801

• Adenosine deaminase inhibition enhances the inotropic response mediated by A1 adenosine receptor in hyperthyroid guinea pig atrium.

  Pharmacological research 20070801

• NTPDase and 5' ecto-nucleotidase expression profiles and the pattern of extracellular ATP metabolism in the Walker 256 tumor.

  Biochimica et biophysica acta 20070801

• RNA editing of the microRNA-151 precursor blocks cleavage by the Dicer-TRBP complex.

  EMBO reports 20070801

• The role of mitochondria in protection of the heart by preconditioning.

  Biochimica et biophysica acta 20070801

• Identification and relative quantification of adenosine to inosine editing in serotonin 2c receptor mRNA by CE.

  Electrophoresis 20070801

• Changes in serum adenosine deaminase activity during normal pregnancy.

  Journal of Korean medical science 20070801

• Qualitative and quantitative analyses of nucleosides and nucleobases in Ganoderma spp. by HPLC-DAD-MS.

  Journal of pharmaceutical and biomedical analysis 20070727

• Acridone-based inhibitors of inosine 5'-monophosphate dehydrogenase: discovery and SAR leading to the identification of N-(2-(6-(4-ethylpiperazin-1-yl)pyridin-3-yl)propan-2-yl)-2- fluoro-9-oxo-9,10-dihydroacridine-3-carboxamide (BMS-566419).

  Journal of medicinal chemistry 20070726

• Facile and rapid access to inosine puromycin analogues through the use of adenylate deaminase.

  Organic letters 20070719

• Altered editing in RNA editing adenosine deaminase ADAR2 gene transcripts of systemic lupus erythematosus T lymphocytes.

  Immunology 20070701

• Localization of broadly selective equilibrative and concentrative nucleoside transporters, hENT1 and hCNT3, in human kidney.

  American journal of physiology. Renal physiology 20070701

• Control of basal extracellular adenosine concentration in rat cerebellum.

  The Journal of physiology 20070701

• An HPLC method for determination of inosine and hypoxanthine in human plasma from healthy volunteers and patients presenting with potential acute cardiac ischemia.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070701

• SHESSLOC: A selective variation of the FUCOUP sequence.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20070701

• Role of the stage-regulated nucleoside transporter TbNT10 in differentiation and adenosine uptake in Trypanosoma brucei.

  Molecular and biochemical parasitology 20070701

• The C-terminal domain of RNA Pol II helps ensure that editing precedes splicing of the GluR-B transcript.

  RNA (New York, N.Y.) 20070701

• Pharmacokinetics and pharmacodynamics of mycophenolic acid after enteric-coated mycophenolate versus mycophenolate mofetil in patients with progressive IgA nephritis.

  Journal of clinical pharmacology 20070701

• Lesion recognition and cleavage by endonuclease V: a single-molecule study.

  Biochemistry 20070619

• Genetic selection for a highly functional cysteine-less membrane protein using site saturation mutagenesis.

  Analytical biochemistry 20070615

• fac-[Re(CO)3(H2O)3]+ nucleoside monophosphate adducts investigated in aqueous solution by multinuclear NMR spectroscopy.

  Inorganic chemistry 20070611

• Auto-inhibition of rat parallel fibre-Purkinje cell synapses by activity-dependent adenosine release.

  The Journal of physiology 20070601

• RNA binding-independent dimerization of adenosine deaminases acting on RNA and dominant negative effects of nonfunctional subunits on dimer functions.

  The Journal of biological chemistry 20070601

• Temporal and mechanistic dissociation of ATP and adenosine release during ischaemia in the mammalian hippocampus.

  Journal of neurochemistry 20070601

• Optimization of CEC for simultaneous determination of eleven nucleosides and nucleobases in Cordyceps using central composite design.

  Electrophoresis 20070601

• Suppressive effect of culture supernatant of erythrocytes and serum from dogs infected with Babesia gibsoni on the morphological maturation of canine reticulocytes in vitro.

  Journal of veterinary science 20070601

• Germination of Bacillus cereus spores adhered to stainless steel.

  International journal of food microbiology 20070530

• Human papillomavirus in high- and low-risk areas of oesophageal squamous cell carcinoma in China.

  British journal of cancer 20070521

• The pancreatohepatorenal cAMP-adenosine mechanism.

  The Journal of pharmacology and experimental therapeutics 20070501

• Inhibitory action of polyunsaturated fatty acids on IMP dehydrogenase.

  Biochimie 20070501

• Neighboring group participation in the transition state of human purine nucleoside phosphorylase.

  Biochemistry 20070501

• Uric acid heralds ischemic tissue injury to mobilize endothelial progenitor cells.

  Journal of the American Society of Nephrology : JASN 20070501

• Biochemical and structural characterization of mammalian-like purine nucleoside phosphorylase from the Archaeon Pyrococcus furiosus.

  The FEBS journal 20070501

• Bacillus decisifrondis sp. nov., isolated from soil underlying decaying leaf foliage.

  International journal of systematic and evolutionary microbiology 20070501

• Electrical detection of germination of viable model Bacillus anthracis spores in microfluidic biochips.

  Lab on a chip 20070501

• Simultaneous application of two neurotrophic factors after spinal cord injury.

  Journal of neurotrauma 20070501

• Identification of an in vivo inhibitor of Bacillus anthracis spore germination.

  The Journal of biological chemistry 20070420

• Nearest neighbor parameters for inosine x uridine pairs in RNA duplexes.

  Biochemistry 20070417

• Editing of the serotonin 2C receptor pre-mRNA: Effects of the Morris Water Maze.

  Gene 20070415

• Hypothesis: RNA editing of microRNA target sites in humans?

  RNA (New York, N.Y.) 20070401

• Inosine promotes recovery of skilled motor function in a model of focal brain injury.

  Brain : a journal of neurology 20070401

• A novel variant L263F in human inosine 5'-monophosphate dehydrogenase 2 is associated with diminished enzyme activity.

  Pharmacogenetics and genomics 20070401

• miRNA editing--we should have inosine this coming.

  Molecular cell 20070323

• Progressive multifocal leukoencephalopathy in purine nucleoside phosphorylase deficiency.

  Brain & development 20070301

• Antiviral activity of tiazofurin and mycophenolic acid against Grapevine leafroll-associated virus 3 in Vitis vinifera explants.

  Antiviral research 20070301

• Molecular interactions underlying the unusually high adenosine affinity of a novel Trypanosoma brucei nucleoside transporter.

  Molecular pharmacology 20070301

• Identification and characterization of a salivary adenosine deaminase from the sand fly Phlebotomus duboscqi, the vector of Leishmania major in sub-Saharan Africa.

  The Journal of experimental biology 20070301

• Localization of the cyclic ADP-ribose-dependent calcium signaling pathway in bovine rod outer segments.

  Investigative ophthalmology & visual science 20070301

• The effects of HCV infection and management on health-related quality of life.

  Hepatology (Baltimore, Md.) 20070301

• Adenosine enhances cytosolic phosphorylation potential and ventricular contractility in stunned guinea pig heart: receptor-mediated and metabolic protection.

  Journal of applied physiology (Bethesda, Md. : 1985) 20070301

• Effect of amplification of desensitized purF and prs on inosine accumulation in Escherichia coli.

  Journal of bioscience and bioengineering 20070301

• Adenosine and lymphocyte regulation.

  Purinergic signalling 20070301

• Purinergic modulation of microglial cell activation.

  Purinergic signalling 20070301

• Adenosine in inflammatory joint diseases.

  Purinergic signalling 20070301

• CD39 and control of cellular immune responses.

  Purinergic signalling 20070301

• Increased serum adenosine deaminase activity in schizophrenic receiving antipsychotic treatment.

  Neuroscience letters 20070227

• Redirection of silencing targets by adenosine-to-inosine editing of miRNAs.

  Science (New York, N.Y.) 20070223

• Influence of sulfur amino acids on the volatile and nonvolatile components of cooked salmon (Salmo salar).

  Journal of agricultural and food chemistry 20070221

• Crystal structure of human inosine triphosphatase. Substrate binding and implication of the inosine triphosphatase deficiency mutation P32T.

  The Journal of biological chemistry 20070202

• Towards elucidation of the mechanism of UV1C, a deoxyribozyme with photolyase activity.

  Journal of molecular biology 20070202

• Effects of 3-phosphoglycerate and other metabolites on the activation of AMP-activated protein kinase by LKB1-STRAD-MO25.

  American journal of physiology. Endocrinology and metabolism 20070201

• Oxypurine and purine nucleoside concentrations in renal vein of allograft are potential markers of energy status of renal tissue.

  Archives of medical research 20070201

• [Cloning and characterization of gerM gene involved in germination in Bacillus thuringiensis].

  Wei sheng wu xue bao = Acta microbiologica Sinica 20070201

• O6-(benzotriazol-1-yl)inosine derivatives: easily synthesized, reactive nucleosides.

  Journal of the American Chemical Society 20070131

• Adenosine metabolism and its effect on methylation potential in cultured cells: methodological considerations.

  Cellular and molecular biology (Noisy-le-Grand, France) 20070121

• Subsecond detection of physiological adenosine concentrations using fast-scan cyclic voltammetry.

  Analytical chemistry 20070115

• Recognition of intestinal epithelial HIF-1alpha activation by Pseudomonas aeruginosa.

  American journal of physiology. Gastrointestinal and liver physiology 20070101

• The phosphofructokinase-B (MJ0406) from Methanocaldococcus jannaschii represents a nucleoside kinase with a broad substrate specificity.

  Extremophiles : life under extreme conditions 20070101

• Deamination of 2',3'-O-isopropylideneadenosine-5'- carboxylic acid catalyzed by adenosine deaminase (ADA) and adenylate deaminase (AMPDA): influence of substrate ionization on the activity of the enzymes.

  Nucleosides, nucleotides & nucleic acids 20070101

• Protective effects of inosine on mice subjected to lethal total-body ionizing irradiation.

  Journal of radiation research 20070101

• Revised procedures for yeast metabolites extraction: application to a glucose pulse to carbon-limited yeast cultures, which reveals a transient activation of the purine salvage pathway.

  Yeast (Chichester, England) 20070101

• The supramolecular helical architecture of 8-oxoinosine and 8-oxoguanosine derivatives.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20070101

• Automated querying of genome databases.

  PLoS computational biology 20070101

• A screen for nuclear transcripts identifies two linked noncoding RNAs associated with SC35 splicing domains.

  BMC genomics 20070101

• Noninfectious gastrointestinal (GI) complications of mycophenolic acid therapy: a consequence of local GI toxicity?

  Transplantation proceedings 20070101

• RNA-editing-mediated exon evolution.

  Genome biology 20070101

• A mathematical model for the adenylosuccinate synthetase reaction involved in purine biosynthesis.

  Theoretical biology & medical modelling 20070101

• Structural and evolutionary bioinformatics of the SPOUT superfamily of methyltransferases.

  BMC bioinformatics 20070101

• Nucleoside transport as a potential target for chemotherapy in malaria.

  Current pharmaceutical design 20070101

• Reactome: a knowledge base of biologic pathways and processes.

  Genome biology 20070101

• Rasburicase represents a new tool for hyperuricemia in tumor lysis syndrome and in gout.

  International journal of medical sciences 20070101

• An insight into the sialome of the oriental rat flea, Xenopsylla cheopis (Rots).

  BMC genomics 20070101

• Oxypurine and nucleoside concentrations in renal veins during reperfusion are predictors of early graft function.

  Scandinavian journal of urology and nephrology 20070101

• Selection strategy and the design of hybrid oligonucleotide primers for RACE-PCR: cloning a family of toxin-like sequences from Agelena orientalis.

  BMC molecular biology 20070101

• Unexpected observations after mapping LongSAGE tags to the human genome.

  BMC bioinformatics 20070101

• Guanosine and inosine (riboxin) eliminate the long-lived protein radicals induced X-ray radiation.

  Doklady. Biochemistry and biophysics 20070101

• Functional diversification of sonic hedgehog paralog enhancers identified by phylogenomic reconstruction.

  Genome biology 20070101

• Histone gene expression and histone mRNA 3' end structure in Caenorhabditis elegans.

  BMC molecular biology 20070101

• Effects of oral adenosine 5'-triphosphate and adenosine in enteric-coated capsules on indomethacin-induced permeability changes in the human small intestine: a randomized cross-over study.

  BMC gastroenterology 20070101

• RNA editing and alternative splicing of the insect nAChR subunit alpha6 transcript: evolutionary conservation, divergence and regulation.

  BMC evolutionary biology 20070101

• Functional characterization of two melanocortin (MC) receptors in lamprey showing orthology to the MC1 and MC4 receptor subtypes.

  BMC evolutionary biology 20070101

• Comparative genomic and bioinformatic approaches for the identification of new adenosine-to-inosine substrates.

  Methods in enzymology 20070101

• Genetic approaches to studying adenosine-to-inosine RNA editing.

  Methods in enzymology 20070101

• A method for finding sites of selective adenosine deamination.

  Methods in enzymology 20070101

• Mouse models to elucidate the functional roles of adenosine-to-inosine editing.

  Methods in enzymology 20070101

• Probing adenosine-to-inosine editing reactions using RNA-containing nucleoside analogs.

  Methods in enzymology 20070101

• Identification of modified residues in RNAs by reverse transcription-based methods.

  Methods in enzymology 20070101

• Complete deficiency of 5'-nucleotidase activity in Escherichia coli leads to loss of growth on purine nucleotides but not of their excretion.

  Journal of molecular microbiology and biotechnology 20070101

• Three-dimensional imaging of Drosophila melanogaster.

  PloS one 20070101

• Large scale comparative codon-pair context analysis unveils general rules that fine-tune evolution of mRNA primary structure.

  PloS one 20070101

• Effects of salicylic acid on post-ischaemic ventricular function and purine efflux in isolated mouse hearts.

  Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20070101

• Connector inversion probe technology: a powerful one-primer multiplex DNA amplification system for numerous scientific applications.

  PloS one 20070101

• Comparison of the contributions of the nuclear and cytoplasmic compartments to global gene expression in human cells.

  BMC genomics 20070101

• Deinococcus geothermalis: the pool of extreme radiation resistance genes shrinks.

  PloS one 20070101

• Behavioral genetics and taste.

  BMC neuroscience 20070101

• A new function for the Bacillus PbuE purine base efflux pump: efflux of purine nucleosides.

  Research in microbiology 20070101

• The nucleation of inosine: the impact of solution chemistry on the appearance of polymorphic and hydrated crystal forms.

  Faraday discussions 20070101

• Recognition of essential purines by the U1A protein.

  BMC biochemistry 20070101

• The chemistry and biology of RNA editing by adenosine deaminases.

  Nucleic acids symposium series (2004) 20070101

• Inosine monophosphate dehydrogenase as a probe in antiviral drug discovery.

  Antiviral chemistry & chemotherapy 20070101

• Metabolic signature of breast cancer cell line MCF-7: profiling of modified nucleosides via LC-IT MS coupling.

  BMC biochemistry 20070101

• Synthesis of 2',3'-dideoxyinosine via radical deoxygenation.

  Nucleosides, nucleotides & nucleic acids 20070101

• Synthesis of a new ribose modified analogue of cyclic inosine diphosphate ribose.

  Nucleosides, nucleotides & nucleic acids 20070101

• Solid phase synthesis of nucleobase and ribose modified inosine nucleoside analogues.

  Nucleosides, nucleotides & nucleic acids 20070101

• 7,5'-O-dibenzylinosines: synthesis and studies on their conformational properties.

  Nucleosides, nucleotides & nucleic acids 20070101

• Restriction site-dependent PCR: an efficient technique for fast cloning of new genes of microorganisms.

  DNA research : an international journal for rapid publication of reports on genes and genomes 20070101

• A scenario on the stepwise evolution of the genetic code.

  Genomics, proteomics & bioinformatics 20070101

• Characterization of copper(II) interactions with sinefungin, a nucleoside antibiotic: combined potentiometric, spectroscopic and DFT studies.

  Bioinorganic chemistry and applications 20070101

• Guanine and inosine nucleotides, nucleosides and oxypurines in snail muscles as potential biomarkers of fluoride toxicity.

  Folia biologica 20070101

• Abstracts of papers presented at the 2007 pittsburgh conference.

  Journal of automated methods & management in chemistry 20070101

• Identification of diverse carbon utilization pathways in Shewanella oneidensis MR-1 via expression profiling.

  Genome informatics. International Conference on Genome Informatics 20070101

• Clastogenic factors as potential biomarkers of increased superoxide production.

  Biomarker insights 20070101

• High-throughput screening for functional adenosine to inosine RNA editing systems.

  ACS chemical biology 20061215

• Profiles of purine biosynthesis, salvage and degradation in disks of potato (Solanum tuberosum L.) tubers.

  Planta 20061201

• Resistance to nitric oxide-induced necrosis in heme oxygenase-1 overexpressing pulmonary epithelial cells associated with decreased lipid peroxidation.

  The Journal of biological chemistry 20061201

• Nutrient control of insulin secretion in isolated normal human islets.

  Diabetes 20061201

• Editor meets silencer: crosstalk between RNA editing and RNA interference.

  Nature reviews. Molecular cell biology 20061201

• Effects of xapA and guaA disruption on inosine accumulation in Escherichia coli.

  Bioscience, biotechnology, and biochemistry 20061201

• Catabolism of adenine nucleotides favors adenosine production following exercise in patients with chronic heart failure.

  Journal of cardiac failure 20061201

• Sprint training reduces urinary purine loss following intense exercise in humans.

  Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 20061201

• Determination of the impurity profile of adenosine by means of ion-pair reversed-phase chromatography.

  Pharmeuropa scientific notes 20061201

• Nonpolar nucleobase analogs illuminate requirements for site-specific DNA cleavage by vaccinia topoisomerase.

  The Journal of biological chemistry 20061124

• Simple synthesis of some pentafluoropropenyl derivatives of pyrimidine and purine based on addition-elimination reaction.

  The Journal of organic chemistry 20061110

• RNA editing by ADAR2 is metabolically regulated in pancreatic islets and beta-cells.

  The Journal of biological chemistry 20061103

• A-to-I pre-mRNA editing of the serotonin 2C receptor: comparisons among inbred mouse strains.

  Gene 20061101

• RNA editing in Drosophila melanogaster: New targets and functional consequences.

  RNA (New York, N.Y.) 20061101

• Adenosine-to-inosine RNA editing: perspectives and predictions.

  Mini reviews in medicinal chemistry 20061101

• First joint italian-german purine club meeting 'progress in purinergic receptor pharmacology and function'.

  Purinergic signalling 20061101

• Non-adenine based purines accelerate wound healing.

  Purinergic signalling 20061101

• Features of adenosine metabolism of mouse heart.

  Purinergic signalling 20061101

• Recent advances in structure and function of cytosolic IMP-GMP specific 5'-nucleotidase II (cN-II).

  Purinergic signalling 20061101

• Acid-base and metal-ion-binding properties of xanthosine 5'-monophosphate (XMP) in aqueous solution: complex stabilities, isomeric equilibria, and extent of macrochelation.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20061025

• Development of inosine monophosphate and its degradation products during aging of pork of different qualities in relation to basic taste and retronasal flavor perception of the meat.

  Journal of agricultural and food chemistry 20061004

• RNA editing level in the mouse is determined by the genomic repeat repertoire.

  RNA (New York, N.Y.) 20061001

• Cellular effects and metabolic stability of N1-cyclic inosine diphosphoribose and its derivatives.

  British journal of pharmacology 20061001

• Determination of inosine monophosphate dehydrogenase activity in human CD4+ cells isolated from whole blood during mycophenolic acid therapy.

  Therapeutic drug monitoring 20061001

• Therapeutic value of serum uric acid levels increasing in the treatment of multiple sclerosis.

  Vojnosanitetski pregled 20061001

• A kinetic, modeling and mechanistic re-analysis of thymidine phosphorylase and some related enzymes.

  Journal of enzyme inhibition and medicinal chemistry 20061001

• Simultaneous determination of adenosine and its metabolites by capillary electrophoresis as a rapid monitoring tool for 5'-nucleotidase activity.

  Journal of chromatography. A 20060929

• Validation and application of a high-performance liquid chromatographic-based assay for determination of the inosine 5'-monophosphate dehydrogenase activity in erythrocytes.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060914

• 5'-O-tritylinosine and analogues as allosteric inhibitors of human thymidine phosphorylase.

  Journal of medicinal chemistry 20060907

• An expedient synthesis of N6-substituted-5'-modified adenosines.

  Bioorganic & medicinal chemistry letters 20060901

• Toxoplasma gondii purine nucleoside phosphorylase biochemical characterization, inhibitor profiles, and comparison with the Plasmodium falciparum ortholog.

  The Journal of biological chemistry 20060901

• Gene expression for enzymes and transporters involved in regulating adenosine and inosine levels in rat forebrain neurons, astrocytes and C6 glioma cells.

  Journal of neuroscience research 20060901

• Structure of Methanocaldococcus jannaschii nucleoside kinase: an archaeal member of the ribokinase family.

  Acta crystallographica. Section D, Biological crystallography 20060901

• Inosine 5'-monophosphate dehydrogenase inhibitors for the treatment of autoimmune diseases.

  Current opinion in drug discovery & development 20060901

• Kinetics of ATP release following compression injury of a peripheral nerve trunk.

  Purinergic signalling 20060901

• Changes of purine and pyrimidine nucleotide biosynthesis during shoot initiation from epicotyl explants of white spruce (Picea glauca).

  Plant science : an international journal of experimental plant biology 20060901

• Structural determinants for N1/N7 cyclization of nicotinamide hypoxanthine 5'-dinucleotide (NHD+) derivatives by ADP-ribosyl cyclase from aplysia californica: Ca2+-mobilizing activity of 8-substituted cyclic inosine 5'-diphosphoribose analogues in T-lymphocytes.

  Journal of medicinal chemistry 20060824

• Comprehensive examination of charged intramembrane residues in a nucleoside transporter.

  The Journal of biological chemistry 20060811

• Biochemical retrosynthesis of 2'-deoxyribonucleosides from glucose, acetaldehyde, and a nucleobase.

  Applied microbiology and biotechnology 20060801

• Proteomic analysis of mitochondria-to-nucleus retrograde response in human cancer.

  Cancer biology & therapy 20060801

• Multiple transients in the pre-steady-state of nucleoside hydrolase reveal complex substrate binding, product base release, and two apparent rates of chemistry.

  Biochemistry 20060801

• Breaking the central dogma by RNA editing.

  Chemical reviews 20060801

• Effects of inosine on neuronal apoptosis and the expression of cytochrome C mRNA following hypoxic-ischemic brain damage in neonatal rats.

  Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20060801

• Application of a solid-phase beta-triphosphitylating reagent in the synthesis of nucleoside beta-triphosphates.

  The Journal of organic chemistry 20060721

• Markedly enhancing lipase-catalyzed synthesis of nucleoside drugs' ester by using a mixture system containing organic solvents and ionic liquid.

  Bioorganic & medicinal chemistry letters 20060715

• Secondary degeneration reduced by inosine after spinal cord injury in rats.

  Spinal cord 20060701

• Primers containing universal bases reduce multiple amoA gene specific DGGE band patterns when analysing the diversity of beta-ammonia oxidizers in the environment.

  Journal of microbiological methods 20060701

• Effects of adenosine deaminase and A1 receptor deficiency in normoxic and ischaemic mouse hearts.

  Cardiovascular research 20060701

• Dimerization of ADAR2 is mediated by the double-stranded RNA binding domain.

  RNA (New York, N.Y.) 20060701

• Effects of inosine on reperfusion injury after heart transplantation.

  European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20060701

• Balance of purines may determine life or death of retinal ganglion cells as A3 adenosine receptors prevent loss following P2X7 receptor stimulation.

  Journal of neurochemistry 20060701

• Calcium-stimulated guanosine--inosine nucleosidase from yellow lupin (Lupinus luteus).

  Phytochemistry 20060701

• Fine-tuning modulation of myenteric motoneurons by endogenous adenosine: on the role of secreted adenosine deaminase.

  Autonomic neuroscience : basic & clinical 20060630

• FRET analysis of in vivo dimerization by RNA-editing enzymes.

  The Journal of biological chemistry 20060616

• GENTEX, a general multiscale model for in vivo tissue exchanges and intraorgan metabolism.

  Philosophical transactions. Series A, Mathematical, physical, and engineering sciences 20060615

• Adenosine as an active component of Antrodia cinnamomea that prevents rat PC12 cells from serum deprivation-induced apoptosis through the activation of adenosine A(2A) receptors.

  Life sciences 20060613

• A conditional mutant deficient in hypoxanthine-guanine phosphoribosyltransferase and xanthine phosphoribosyltransferase validates the purine salvage pathway of Leishmania donovani.

  The Journal of biological chemistry 20060609

• Modified nucleosides: an accurate tumour marker for clinical diagnosis of cancer, early detection and therapy control.

  British journal of cancer 20060605

• cAMP-adenosine pathway in the proximal tubule.

  The Journal of pharmacology and experimental therapeutics 20060601

• Nucleotide mutations in purA gene and pur operon promoter discovered in guanosine- and inosine-producing Bacillus subtilis strains.

  Biotechnology letters 20060601

• Clinical study on Ganbi decoction in treating antituberculotic agent-caused liver injury.

  Chinese journal of integrative medicine 20060601

• Improved circadian sleep-wake cycle in infants fed a day/night dissociated formula milk.

  Neuro endocrinology letters 20060601

• Physiological roles for ecto-5'-nucleotidase (CD73).

  Purinergic signalling 20060601

• The E-NTPDase family of ectonucleotidases: Structure function relationships and pathophysiological significance.

  Purinergic signalling 20060601

• Polymorphism of the signaling molecule c-di-GMP.

  Journal of the American Chemical Society 20060531

• EPR and ENDOR study of radiation-induced radical formation in purines: sodium inosine crystals X-irradiated at 10 K.

  The journal of physical chemistry. A 20060525

• Structural and kinetic characterization of Escherichia coli TadA, the wobble-specific tRNA deaminase.

  Biochemistry 20060523

• Inosine released after hypoxia activates hepatic glucose liberation through A3 adenosine receptors.

  American journal of physiology. Endocrinology and metabolism 20060501

• Transport of nucleosides across the Plasmodium falciparum parasite plasma membrane has characteristics of PfENT1.

  Molecular microbiology 20060501

• [Effects of inosine injection in expression of myosin heavy chain in intrafusal and extrafusal myofibers in soleus muscle of tail-suspended rats].

  Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20060501

• Guanosine and inosine display antioxidant activity, protect DNA in vitro from oxidative damage induced by reactive oxygen species, and serve as radioprotectors in mice.

  Radiation research 20060501

• Quality evaluation of Cordyceps through simultaneous determination of eleven nucleosides and bases by RP-HPLC.

  Journal of separation science 20060501

• Extensive adenosine-to-inosine editing detected in Alu repeats of antisense RNAs reveals scarcity of sense-antisense duplex formation.

  FEBS letters 20060417

• Impact of quorum sensing on fitness of Pseudomonas aeruginosa.

  International journal of medical microbiology : IJMM 20060401

• Inosine reduces microcirculatory disturbance and inflammatory organ damage in experimental acute pancreatitis in rats.

  American journal of surgery 20060401

• Identification and classification of conserved RNA secondary structures in the human genome.

  PLoS computational biology 20060401

• The PnrA (Tp0319; TmpC) lipoprotein represents a new family of bacterial purine nucleoside receptor encoded within an ATP-binding cassette (ABC)-like operon in Treponema pallidum.

  The Journal of biological chemistry 20060324

• Intense exercise induces the degradation of adenine nucleotide and purine nucleotide synthesis via de novo pathway in the rat liver.

  European journal of applied physiology 20060301

• Effect of trimetazidine on the nucleotide profile in rat kidney with ischemia-reperfusion injury.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20060301

• Effect of allopurinol on brain adenosine levels during hypoxia in newborn piglets.

  Brain research 20060216

• The nucleotide derivatives inosine and inosinic acid inhibit intestinal absorption of mizoribine in rats.

  European journal of pharmacology 20060215

• Fluorinase mediated C-(18)F bond formation, an enzymatic tool for PET labelling.

  Chemical communications (Cambridge, England) 20060214

• Assay of adenosine deaminase isoforms by HPLC.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060202

• Inosine 5'-monophosphate dehydrogenase inhibition by mycophenolic acid impairs maturation and function of dendritic cells.

  Clinica chimica acta; international journal of clinical chemistry 20060201

• Crystal structure of Staphylococcus aureus tRNA adenosine deaminase TadA in complex with RNA.

  Nature structural & molecular biology 20060201

• Interaction of intestinal nucleoside transporter hCNT2 with amino acid ester prodrugs of floxuridine and 2-bromo-5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole.

  Biological & pharmaceutical bulletin 20060201

• Identification and characterization of a germination operon from Bacillus thuringiensis.

  Antonie van Leeuwenhoek 20060201

• The fluorinase from Streptomyces cattleya is also a chlorinase.

  Angewandte Chemie (International ed. in English) 20060123

• Mycophenolic acid-induced replication arrest, differentiation markers and cell death of androgen-independent prostate cancer cells DU145.

  Cancer letters 20060108

• C to U editing stimulates A to I editing in the anticodon loop of a cytoplasmic threonyl tRNA in Trypanosoma brucei.

  The Journal of biological chemistry 20060106

• Molecular basis for nucleotide-binding specificity: role of the exocyclic amino group 'N2' in recognition by a guanylyl-ribonuclease.

  Journal of molecular biology 20060106

• Purine and pyrimidine metabolism and electrocortical brain activity during hypotension in near-term lambs.

  Biology of the neonate 20060101

• Functional characterization and haplotype analysis of polymorphisms in the human equilibrative nucleoside transporter, ENT2.

  Drug metabolism and disposition: the biological fate of chemicals 20060101

• Extracellular inosine participates in tumor necrosis factor-alpha induced nitric oxide production in cultured Sertoli cells.

  Molecular and cellular biochemistry 20060101

• Modulation of microRNA processing and expression through RNA editing by ADAR deaminases.

  Nature structural & molecular biology 20060101

• Characterization of brimonidine transport in retinal pigment epithelium.

  Investigative ophthalmology & visual science 20060101

• Relatively small increases in the steady-state levels of nucleobase deamination products in DNA from human TK6 cells exposed to toxic levels of nitric oxide.

  Chemical research in toxicology 20060101

• Colour variation in red grapevines (Vitis vinifera L.): genomic organisation, expression of flavonoid 3'-hydroxylase, flavonoid 3',5'-hydroxylase genes and related metabolite profiling of red cyanidin-/blue delphinidin-based anthocyanins in berry skin.

  BMC genomics 20060101

• Inosine monophosphate dehydrogenase activity in renal allograft recipients during mycophenolate treatment.

  Scandinavian journal of clinical and laboratory investigation 20060101

• Functional and molecular characterization of adenosine transport at the rat inner blood-retinal barrier.

  Biochimica et biophysica acta 20060101

• Hypoxanthine as a graft ischemia marker stimulates catalase activity in the renal vein during reperfusion in humans.

  Transplantation proceedings 20060101

• Suppression of inflammation by low-dose methotrexate is mediated by adenosine A2A receptor but not A3 receptor activation in thioglycollate-induced peritonitis.

  Arthritis research & therapy 20060101

• [Germination of Bacillus anthracis spores].

  Zhurnal mikrobiologii, epidemiologii, i immunobiologii 20060101

• Genetic algorithm learning as a robust approach to RNA editing site prediction.

  BMC bioinformatics 20060101

• Cerebrospinal fluid adenosine deaminase activity: a complimentary tool in the early diagnosis of tuberculous meningitis.

  Cerebrospinal fluid research 20060101

• RNA editing of human microRNAs.

  Genome biology 20060101

• Does adenosine deaminase play a key role in coronary artery disease.

  Medical hypotheses 20060101

• A case study in pathway knowledgebase verification.

  BMC bioinformatics 20060101

• Detection of Norovirus genogroup I and II by multiplex real-time RT- PCR using a 3'-minor groove binder-DNA probe.

  BMC infectious diseases 20060101

• Quality control for terms and definitions in ontologies and taxonomies.

  BMC bioinformatics 20060101

• The complete plastid genome sequence of the parasitic green alga Helicosporidium sp. is highly reduced and structured.

  BMC biology 20060101

• Characteristic abnormalities in cerebrospinal fluid biochemistry in children with cerebral malaria compared to viral encephalitis.

  Cerebrospinal fluid research 20060101

• The Yersinia pestis gcvB gene encodes two small regulatory RNA molecules.

  BMC microbiology 20060101

• Guanosine and inosine as natural antioxidants and radioprotectors for mice exposed to lethal doses of gamma-radiation.

  Doklady. Biochemistry and biophysics 20060101

• Transcriptome analysis of Deinagkistrodon acutus venomous gland focusing on cellular structure and functional aspects using expressed sequence tags.

  BMC genomics 20060101

• Recent developments in our understanding of the renal basis of hyperuricemia and the development of novel antihyperuricemic therapeutics.

  Arthritis research & therapy 20060101

• The potential regulation of L1 mobility by RNA interference.

  Journal of biomedicine & biotechnology 20060101

• Concentration of nucleosides and related compounds in cerebral and cerebellar cortical areas and white matter of the human brain.

  Cellular and molecular neurobiology 20060101

• RNA editing in hepatitis delta virus.

  Current topics in microbiology and immunology 20060101

• Ursodeoxycholic acid in the treatment of intraheptic cholestasis of pregnancy.

  Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20060101

• High-performance liquid chromatography (HPLC) determination of inosine, a potential biomarker for initial cardiac ischaemia, using isolated mouse hearts.

  Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20060101

• Leishmania isoenzyme polymorphisms in Ecuador: relationships with geographic distribution and clinical presentation.

  BMC infectious diseases 20060101

• Elucidating the mechanism of wound contraction: rapid versus sustained myosin ATPase activity in attached-delayed-released compared with free-floating fibroblast-populated collagen lattices.

  Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 20060101

• Thymidine phosphorylase is noncompetitively inhibited by 5'-O-trityl-inosine (KIN59) and related compounds.

  Nucleosides, nucleotides & nucleic acids 20060101

• Maize haplotype with a helitron-amplified cytidine deaminase gene copy.

  BMC genetics 20060101

• Methotrexate enhances the anti-inflammatory effect of CF101 via up-regulation of the A3 adenosine receptor expression.

  Arthritis research & therapy 20060101

• The conserved protein kinase-A target motif in synapsin of Drosophila is effectively modified by pre-mRNA editing.

  BMC neuroscience 20060101

• A-to-I RNA editing and human disease.

  RNA biology 20060101

• Systematic assignment of thermodynamic constraints in metabolic network models.

  BMC bioinformatics 20060101

• Detection of photoinduced electron transfer from Sso7d to DNA.

  Nucleic acids symposium series (2004) 20060101

• p150 ADAR1 isoform involved in maintenance of HeLa cell proliferation.

  BMC cancer 20060101

• [Guanosine and inosine as natural geneprotectors for mice blood cells exposed to X-rays].

  Radiatsionnaia biologiia, radioecologiia 20060101

• Quantitative gas chromatography mass spectrometric analysis of 2'-deoxyinosine in tissue DNA.

  Nature protocols 20060101

• A highly facile and efficient one-step synthesis of N6-adenosine and N6-2'-deoxyadenosine derivatives.

  Organic letters 20051222

• Guanidine derivatives rescue the Arg418Ala mutation of Tritrichomonas foetus IMP dehydrogenase.

  Biochemistry 20051220

• Differential interactions of G-proteins and adenylyl cyclase with nucleoside 5'-triphosphates, nucleoside 5'-[gamma-thio]triphosphates and nucleoside 5'-[beta,gamma-imido]triphosphates.

  Biochemical pharmacology 20051219

• Differentiation of androgen-independent prostate cancer PC-3 cells is associated with increased nuclear factor-kappaB activity.

  Cancer research 20051215

• Novel 7-methoxy-6-oxazol-5-yl-2,3-dihydro-1H-quinazolin-4-ones as IMPDH inhibitors.

  Bioorganic & medicinal chemistry letters 20051201

• Development of stealth liposome formulation of 2'-deoxyinosine as 5-fluorouracil modulator: in vitro and in vivo study.

  Pharmaceutical research 20051201

• CBS domains: structure, function, and pathology in human proteins.

  American journal of physiology. Cell physiology 20051201

• Inhibitor screening using immobilized enzyme reactor chromatography/mass spectrometry.

  Analytical chemistry 20051201

• Oxanosine is a substrate of adenosine deaminase. Implications for the quest for a toxicological marker for nitrosation activity.

  Chemical research in toxicology 20051201

• Inosine infusion prevents mortality in endotoxic shock.

  The Journal of trauma 20051201

• [The world of RNA modifications; another topics of functional RNAs].

  Seikagaku. The Journal of Japanese Biochemical Society 20051201

• 3-Hydrogenkwadaphnin targets inosine 5'-monophosphate dehydrogenase and triggers post-G1 arrest apoptosis in human leukemia cell lines.

  The international journal of biochemistry & cell biology 20051101

• Simultaneous high performance liquid chromatographic separation of purines, pyrimidines, N-acetylated amino acids, and dicarboxylic acids for the chemical diagnosis of inborn errors of metabolism.

  Clinical biochemistry 20051101

• Novel multisubstrate inhibitors of mammalian purine nucleoside phosphorylase.

  Acta crystallographica. Section D, Biological crystallography 20051101

• [High intestinal transport activity for nucleosides in cattle: a synopsis].

  DTW. Deutsche tierarztliche Wochenschrift 20051101

• Competitive reactions of L-methionine and 5'-GMP towards platinum (II) complexes.

  Medicinal chemistry (Shariqah (United Arab Emirates)) 20051101

• Extracellular inosine modulates ERK 1/2 and p38 phosphorylation in cultured Sertoli cells: possible participation in TNF-alpha modulation of ERK 1/2.

  Life sciences 20051028

• Apoptosis induced by nucleosides in the human hepatoma HepG2.

  World journal of gastroenterology 20051028

• A functional genetic variation of adenosine deaminase affects the duration and intensity of deep sleep in humans.

  Proceedings of the National Academy of Sciences of the United States of America 20051025

• Post mortem degradation of nucleosides in the brain: comparison of human and rat brains for estimation of in vivo concentration of nucleosides.

  Journal of neuroscience methods 20051015

• Development of broadly targeted human endogenous gammaretroviral pol-based real time PCRs Quantitation of RNA expression in human tissues.

  Journal of virological methods 20051001

• Adenine nucleotide metabolism in human blood--important roles for leukocytes and erythrocytes.

  Journal of thrombosis and haemostasis : JTH 20051001

• The influence of allopurinol on urinary purine loss after repeated sprint exercise in man.

  Metabolism: clinical and experimental 20051001

• The identification of 5'-fluoro-5-deoxyinosine as a shunt product in cell free extracts of Streptomyces cattleya.

  Bioorganic chemistry 20051001

• Automation of the glycerolization of red blood cells with the high-separation bowl in the Haemonetics ACP 215 instrument.

  Transfusion 20051001

• Identification of an ITPase/XTPase in Escherichia coli by structural and biochemical analysis.

  Structure (London, England : 1993) 20051001

• Protein molecular function prediction by Bayesian phylogenomics.

  PLoS computational biology 20051001

• Development of quality evaluation sensor for fish freshness control based on KI value.

  Biosensors & bioelectronics 20050915

• Biochemical and structural studies of A-to-I editing by tRNA:A34 deaminases at the wobble position of transfer RNA.

  Biochemistry 20050913

• Is Arg418 the catalytic base required for the hydrolysis step of the IMP dehydrogenase reaction?

  Biochemistry 20050906

• Synthesis and reactions of 2-chloro- and 2-tosyloxy-2'-deoxyinosine derivatives.

  The Journal of organic chemistry 20050902

• Glutamine inhibits cytokine-induced apoptosis in human colonic epithelial cells via the pyrimidine pathway.

  American journal of physiology. Gastrointestinal and liver physiology 20050901

• Molecular pharmacology of adenosine transport in Trypanosoma brucei: P1/P2 revisited.

  Molecular pharmacology 20050901

• Protective mechanisms of inosine in platelet activation and cerebral ischemic damage.

  Arteriosclerosis, thrombosis, and vascular biology 20050901

• The yicM (nepI) gene of Escherichia coli encodes a major facilitator superfamily protein involved in efflux of purine ribonucleosides.

  FEMS microbiology letters 20050901

• Inosine, calcium channels, and neuroprotection against ischemic brain injury.

  Stroke 20050901

• Myocardial and coronary sinus purines as indicators of pig heart energy metabolism during reperfusion after extracorporeal circulation.

  Acta physiologica Scandinavica 20050901

• Structures of Plasmodium falciparum purine nucleoside phosphorylase complexed with sulfate and its natural substrate inosine.

  Acta crystallographica. Section D, Biological crystallography 20050901

• Letter from the editor: Adenosine-to-inosine RNA editing in Alu repeats in the human genome.

  EMBO reports 20050901

• Dynamic purine signaling and metabolism during neutrophil-endothelial interactions.

  Purinergic signalling 20050901

• A novel nucleophilic approach to 1-alkyladenosines. A two-step synthesis of [1-15N]adenosine from inosine.

  Chemical communications (Cambridge, England) 20050821

• Autosomal dominant retinitis pigmentosa mutations in inosine 5'-monophosphate dehydrogenase type I disrupt nucleic acid binding.

  The Biochemical journal 20050815

• Precursors of chicken flavor. II. Identification of key flavor precursors using sensory methods.

  Journal of agricultural and food chemistry 20050810

• Merits of HPLC-based method over spectrophotometric method for assessing the kinetics and inhibition of mammalian adenosine deaminase.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050805

• A TaqMan PCR assay using degenerate primers for the quantitative detection of woodchuck hepatitis virus DNA of multiple genotypes.

  Molecular and cellular probes 20050801

• Micromolar HgCl2 concentrations transitorily duplicate the ATP level in Saccharomyces cerevisiae cells.

  FEBS letters 20050801

• The binding of IMP to ribonuclease A.

  The FEBS journal 20050801

• Crystallization and preliminary X-ray crystallographic analysis of adenosine 5'-monophosphate deaminase (AMPD) from Arabidopsis thaliana in complex with coformycin 5'-phosphate.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20050801

• Inosine improves islet xenograft survival in immunocompetent diabetic mice.

  European journal of medical research 20050729

• Precursors of chicken flavor. I. Determination of some flavor precursors in chicken muscle.

  Journal of agricultural and food chemistry 20050727

• DNA cytosine C5 methyltransferase Dnmt1: catalysis-dependent release of allosteric inhibition.

  Biochemistry 20050712

• Investigation of methaemoglobin reduction by extracellular NADH in mammalian erythrocytes.

  The international journal of biochemistry & cell biology 20050701

• A role for adenosine deaminase in Drosophila larval development.

  PLoS biology 20050701

• Study of the reactions between platinum(II) complexes and L-methionine in the presence and absence of 5'-GMP.

  Journal of inorganic biochemistry 20050701

• Characterization of an ecto-ATPase activity in Cryptococcus neoformans.

  FEMS yeast research 20050701

• Structure of human PNP complexed with ligands.

  Acta crystallographica. Section D, Biological crystallography 20050701

• Amplification of depolarization-induced and ryanodine-sensitive cytosolic Ca2+ elevation by synthetic carbocyclic analogs of cyclic ADP-ribose and their antagonistic effects in NG108-15 neuronal cells.

  Journal of neurochemistry 20050701

• Dual roles of glycosyl torsion angle conformation and stereochemical configuration in butadiene oxide-derived N1 beta-hydroxyalkyl deoxyinosine adducts: a structural perspective.

  Chemical research in toxicology 20050701

• Effects of edd and pgi disruptions on inosine accumulation in Escherichia coli.

  Bioscience, biotechnology, and biochemistry 20050701

• Adenosine and purine nucleosides prevent the disruption of mitochondrial transmembrane potential by peroxynitrite in rat primary astrocytes.

  Archives of pharmacal research 20050701

• Identification of a subversive substrate of Trichomonas vaginalis purine nucleoside phosphorylase and the crystal structure of the enzyme-substrate complex.

  The Journal of biological chemistry 20050610

• Rapid synthetic route toward structurally modified derivatives of cyclic adenosine 5'-diphosphate ribose.

  The Journal of organic chemistry 20050610

• [N,1-(15)N2]-2'-deoxyadenosines.

  Organic letters 20050609

• Skeletal muscle contractile performance and ADP accumulation in adenylate kinase-deficient mice.

  American journal of physiology. Cell physiology 20050601

• A bioinformatic screen for novel A-I RNA editing sites reveals recoding editing in BC10.

  Bioinformatics (Oxford, England) 20050601

• A new yeast poly(A) polymerase complex involved in RNA quality control.

  PLoS biology 20050601

• Purine nucleoside-mediated protection of chemical hypoxia-induced neuronal injuries involves p42/44 MAPK activation.

  Neurochemistry international 20050601

• The RISC subunit Tudor-SN binds to hyper-edited double-stranded RNA and promotes its cleavage.

  Nature structural & molecular biology 20050601

• Selective upregulation of the A3 adenosine receptor in eyes with pseudoexfoliation syndrome and glaucoma.

  Investigative ophthalmology & visual science 20050601

• An increase in the ATP levels occurs in cerebellar granule cells en route to apoptosis in which ATP derives from both oxidative phosphorylation and anaerobic glycolysis.

  Biochimica et biophysica acta 20050601

• Extracellular cyclic AMP-adenosine pathway in isolated adipocytes and adipose tissue.

  Obesity research 20050601

• Expression, purification, crystallization and preliminary X-ray analysis of a nucleoside kinase from the hyperthermophile Methanocaldococcus jannaschii.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20050601

• Neuroprotection by adenosine in the brain: From A(1) receptor activation to A (2A) receptor blockade.

  Purinergic signalling 20050601

• Structure-activity relationships of dinucleotides: Potent and selective agonists of P2Y receptors.

  Purinergic signalling 20050601

• Polyvalent degenerate oligonucleotides reverse transcription-polymerase chain reaction: a polyvalent detection and characterization tool for trichoviruses, capilloviruses, and foveaviruses.

  Phytopathology 20050601

• Computational study of IAG-nucleoside hydrolase: determination of the preferred ground state conformation and the role of active site residues.

  Biochemistry 20050531

• Purification and characterization of RihC, a xanthosine-inosine-uridine-adenosine-preferring hydrolase from Salmonella enterica serovar Typhimurium.

  Biochimica et biophysica acta 20050525

• Activation of glutamate receptors promotes a calcium-dependent and transporter-mediated release of purines in cultured avian retinal cells: possible involvement of calcium/calmodulin-dependent protein kinase II.

  Neurochemistry international 20050501

• The emerging role of adenosine deaminases in insects.

  Insect biochemistry and molecular biology 20050501

• A novel RNA pentaloop fold involved in targeting ADAR2.

  RNA (New York, N.Y.) 20050501

• Purine nucleosides stimulate Na/K ATPase, and prolong survival in hemorrhagic shock.

  The Journal of trauma 20050501

• [Application of urinary nucleosides in the diagnosis and surgical monitoring of colorectal cancer].

  Zhonghua wai ke za zhi [Chinese journal of surgery] 20050501

• Enhancement of inosine production by Bacillus subtilis through suppression of carbon overflow by sodium citrate.

  Biotechnology letters 20050501

• Crystal structure of tRNA adenosine deaminase (TadA) from Aquifex aeolicus.

  The Journal of biological chemistry 20050422

• Functional characterization of novel human and mouse equilibrative nucleoside transporters (hENT3 and mENT3) located in intracellular membranes.

  The Journal of biological chemistry 20050422

• Escherichia coli purine nucleoside phosphorylase II, the product of the xapA gene.

  Journal of molecular biology 20050422

• Expression of interferon-inducible RNA adenosine deaminase ADAR1 during pathogen infection and mouse embryo development involves tissue-selective promoter utilization and alternative splicing.

  The Journal of biological chemistry 20050415

• Inosine substitutions demonstrate that intramolecular DNA quadruplexes adopt different conformations in the presence of sodium and potassium.

  Bioorganic & medicinal chemistry letters 20050415

• [Expression of matrix metalloproteinase-9 in renal tissues of rats with chronic allograft nephropathy at early stage and the role thereof].

  Zhonghua yi xue za zhi 20050413

• Evidence for the involvement of cytosolic 5'-nucleotidase (cN-II) in the synthesis of guanine nucleotides from xanthosine.

  The Journal of biological chemistry 20050408

• Uptake and utilization of nucleosides for energy repletion.

  The international journal of biochemistry & cell biology 20050401

• Synthesis of a methylene analog of 5-amino-1-beta-D-ribofuranosylimidazole-4-carboxamide monophosphate (ZMP).

  Bioscience, biotechnology, and biochemistry 20050401

• Evidence for Watson-Crick and not Hoogsteen or wobble base pairing in the selection of nucleotides for insertion opposite pyrimidines and a thymine dimer by yeast DNA pol eta.

  Biochemistry 20050329

• A Methanocaldococcus jannaschii archaeal signature gene encodes for a 5-formaminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate synthetase. A new enzyme in purine biosynthesis.

  The Journal of biological chemistry 20050325

• Solid state dehydration processes: mechanism of water loss from crystalline inosine dihydrate.

  The journal of physical chemistry. B 20050324

• Molecular determinants and guided evolution of species-specific RNA editing.

  Nature 20050317

• Targeting a novel Plasmodium falciparum purine recycling pathway with specific immucillins.

  The Journal of biological chemistry 20050311

• Structure of an oligodeoxynucleotide containing a butadiene oxide-derived N1 beta-hydroxyalkyl deoxyinosine adduct in the human N-ras codon 61 sequence.

  Biochemistry 20050308

• A combined computational and experimental study of the hydrogen-bonded dimers of xanthine and hypoxanthine.

  The journal of physical chemistry. A 20050303

• In vivo inosine protects alveolar epithelial type 2 cells against hyperoxia-induced DNA damage through MAP kinase signaling.

  American journal of physiology. Lung cellular and molecular physiology 20050301

• Inosine reduces ischemic brain injury in rats.

  Stroke 20050301

• Identification and characterization of purine nucleoside transporters from Crithidia fasciculata.

  Molecular and biochemical parasitology 20050301

• Model platinum nucleobase and nucleoside complexes and antitumor activity: X-ray crystal structure of [PtIV(trans-1R,2R-diaminocyclohexane)trans-(acetate)2(9-ethylguanine)Cl]NO3.H2O.

  Journal of inorganic biochemistry 20050301

• Cyclosporin and tacrolimus increase plasma levels of adenosine in kidney transplanted patients.

  Transplant international : official journal of the European Society for Organ Transplantation 20050301

• [Quantitative analysis of the nucleosides in Cordyceps sinensis with capillary zone electrophoresis].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050301

• Astrocytes and neurons: different roles in regulating adenosine levels.

  Neurological research 20050301

• Identification and functional characterization of variants in human concentrative nucleoside transporter 3, hCNT3 (SLC28A3), arising from single nucleotide polymorphisms in coding regions of the hCNT3 gene.

  Pharmacogenetics and genomics 20050301

• [Studies on the germination of Bacillus anthracoides spores induced by nutrient germinant].

  Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi 20050301

• Vigilins bind to promiscuously A-to-I-edited RNAs and are involved in the formation of heterochromatin.

  Current biology : CB 20050222

• Is abundant A-to-I RNA editing primate-specific?

  Trends in genetics : TIG 20050201

• The receptor mechanism mediating the contractile response to adenosine on lung parenchymal strips from actively sensitised, allergen-challenged Brown Norway rats.

  Naunyn-Schmiedeberg's archives of pharmacology 20050201

• Genetic analysis and functional characterization of polymorphisms in the human concentrative nucleoside transporter, CNT2.

  Pharmacogenetics and genomics 20050201

• Atomic force microscopy study of the structural effects induced by echinomycin binding to DNA.

  Journal of molecular biology 20050128

• Second-site suppression of a nonfunctional mutation within the Leishmania donovani inosine-guanosine transporter.

  The Journal of biological chemistry 20050121

• Identification of new targets of Drosophila pre-mRNA adenosine deaminase.

  Physiological genomics 20050120

• Active site plasticity of endonuclease V from Salmonella typhimurium.

  Biochemistry 20050118

• P-site pairing subtleties revealed by the effects of different tRNAs on programmed translational bypassing where anticodon re-pairing to mRNA is separated from dissociation.

  Journal of molecular biology 20050107

• Enzymatic transition states: thermodynamics, dynamics and analogue design.

  Archives of biochemistry and biophysics 20050101

• Protective effect of adenosine and purine nucleos(t)ides against the death by hydrogen peroxide and glucose deprivation in rat primary astrocytes.

  Neuroscience research 20050101

• Taxonomic distribution and quantitative analysis of free purine and pyrimidine nucleosides in snake venoms.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20050101

• A comprehensive update of the sequence and structure classification of kinases.

  BMC structural biology 20050101

• Deamination of adenosine by extracts of Penicillium politans NRC-510.

  Journal of basic microbiology 20050101

• Synthesis and biological evaluation of 2',3'-didehydro-2',3'-dideoxy-9-deazaguanosine, a monophosphate prodrug and two analogues, 2',3'-dideoxy-9-deazaguanosine and 2',3'-didehydro-2',3'-dideoxy-9-deazainosine.

  Nucleosides, nucleotides & nucleic acids 20050101

• In vitro combination studies of tenofovir and other nucleoside analogues with ribavirin against HIV-1.

  Antiviral therapy 20050101

• Dynamic simulation of red blood cell metabolism and its application to the analysis of a pathological condition.

  Theoretical biology & medical modelling 20050101

• Effects of mycophenolate mofetil on key pattern of coronary restenosis: a cascade of in vitro and ex vivo models.

  BMC cardiovascular disorders 20050101

• RNA editing: a molecular mechanism for the fine modulation of neuronal transmission.

  Acta neurochirurgica. Supplement 20050101

• Metabolic adaptations to repeated periods of contraction with reduced blood flow in canine skeletal muscle.

  BMC physiology 20050101

• Purine metabolism in pigs and humans and its implications for xenotransplantation.

  Nucleosides, nucleotides & nucleic acids 20050101

• Ischemic preconditioning attenuates portal venous plasma concentrations of purines following warm liver ischemia in man.

  European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes 20050101

• [Immunomodulating effects induced by the regulators of energy metabolism and the exposure to heat and cold in case of toxic affection of the kidneys].

  Patologicheskaia fiziologiia i eksperimental'naia terapiia 20050101

• Kinetic properties of Cellulomonas sp. purine nucleoside phosphorylase with typical and non-typical substrates: implications for the reaction mechanism.

  Nucleosides, nucleotides & nucleic acids 20050101

• Synthesis of a new N-9 ribityl analogue of cyclic inosine diphosphate ribose (cIDPR) as a mimic of cyclic ADP ribose (cADPR).

  Nucleosides, nucleotides & nucleic acids 20050101

• Immunochemical, biomolecular and biochemical characterization of bovine epithelial intestinal primocultures.

  BMC cell biology 20050101

• Nucleoside transport in primary cultured rabbit tracheal epithelial cells.

  Journal of drug targeting 20050101

• Comparison of gene expression signatures of diamide, H2O2 and menadione exposed Aspergillus nidulans cultures--linking genome-wide transcriptional changes to cellular physiology.

  BMC genomics 20050101

• Dietary rescue of fumble--a Drosophila model for pantothenate-kinase-associated neurodegeneration.

  Journal of inherited metabolic disease 20050101

• Comparative hydrolysis of extracellular adenine nucleotides and adenosine in synaptic membranes from porcine brain cortex, hippocampus, cerebellum and medulla oblongata.

  Brain research 20041224

• Differentiation of human prostate cancer PC-3 cells induced by inhibitors of inosine 5'-monophosphate dehydrogenase.

  Cancer research 20041215

• Glutathione-dependent reduction of arsenate in human erythrocytes--a process independent of purine nucleoside phosphorylase.

  Toxicological sciences : an official journal of the Society of Toxicology 20041201

• Widespread A-to-I RNA editing of Alu-containing mRNAs in the human transcriptome.

  PLoS biology 20041201

• A survey of RNA editing in human brain.

  Genome research 20041201

• Regulatory role of dADAR in ROS metabolism in Drosophila CNS.

  Brain research. Molecular brain research 20041124

• Equilibrium, kinetic and HPLC study of the reactions between platinum(II) complexes and DNA constituents in the presence and absence of glutathione.

  Dalton transactions (Cambridge, England : 2003) 20041121

• Synthesis and degradation of nucleobases and nucleic acids by formamide in the presence of montmorillonites.

  Chembiochem : a European journal of chemical biology 20041105

• Simultaneous determination of six main nucleosides and bases in natural and cultured Cordyceps by capillary electrophoresis.

  Journal of chromatography. A 20041105

• Metabolic regulation of ATP breakdown and of adenosine production in rat brain extracts.

  The international journal of biochemistry & cell biology 20041101

• Allelic isoforms of the H+/nucleoside co-transporter (CaCNT) from Candida albicans reveal separate high- and low-affinity transport systems for nucleosides.

  Yeast (Chichester, England) 20041101

• Intrapericardial adenine nucleosides induce elevation of endothelin-1 concentration in the pericardial space of the dog heart.

  Journal of cardiovascular pharmacology 20041101

• Cardiovascular responses to catecholamines and interactions with endothelin-1 and adenine nucleosides in the pericardium of the dog heart.

  Journal of cardiovascular pharmacology 20041101

• Nitrogen oxide blockade does not aggravate the endothelin-1-induced myocardial ischemia and release of purine metabolites from the dog heart.

  Journal of cardiovascular pharmacology 20041101

• The influence of DNA stiffness upon nucleosome formation.

  Journal of structural biology 20041001

• Evidence for auto-inhibition by the N terminus of hADAR2 and activation by dsRNA binding.

  RNA (New York, N.Y.) 20041001

• Identification and characterization of a novel gene of grouper iridovirus encoding a purine nucleoside phosphorylase.

  The Journal of general virology 20041001

• Effect of concentration on taste-taste interactions in foods for elderly and young subjects.

  Chemical senses 20041001

• Purine nucleoside phosphorylase activity in rat cerebrospinal fluid.

  Neurochemical research 20041001

• Mitochondrial function dependent proliferation assay for the diagnosis of mitochondrial disorders in human fibroblasts.

  Nucleosides, nucleotides & nucleic acids 20041001

• Efficiency and mechanisms of the antioxidant effect of standard therapy and refracterin in the treatment of chronic heart failure in elderly patients with postinfarction cardiosclerosis.

  Bulletin of experimental biology and medicine 20041001

• Biochemical brain markers and purinergic parameters in rat CSF after seizure induced by pentylenetetrazol.

  Brain research bulletin 20040930

• Cryptosporidium parvum IMP dehydrogenase: identification of functional, structural, and dynamic properties that can be exploited for drug design.

  The Journal of biological chemistry 20040924

• On the role of the starved codon and the takeoff site in ribosome bypassing in Escherichia coli.

  Journal of molecular biology 20040917

• A transition state analogue for an RNA-editing reaction.

  Journal of the American Chemical Society 20040915

• Structural bioinformatics study of PNP from Schistosoma mansoni.

  Biochemical and biophysical research communications 20040910

• Impact of modifications of heterocyclic bases in CpG dinucleotides on their immune-modulatory activity.

  Journal of leukocyte biology 20040901

• Widespread RNA editing of embedded alu elements in the human transcriptome.

  Genome research 20040901

• Effect of lead ions on rat erythrocyte purine content.

  Biological trace element research 20040901

• [Uric acid and multiple sclerosis].

  Therapeutische Umschau. Revue therapeutique 20040901

• Synthesis of oligoribonucleotides containing N6-alkyladenosine and 2-methylthio-N6-alkyladenosine.

  Current protocols in nucleic acid chemistry 20040901

• SNAr iodination of 6-chloropurine nucleosides: aromatic Finkelstein reactions at temperatures below -40 degrees C.

  Organic letters 20040819

• Analysis of solvent nucleophile isotope effects: evidence for concerted mechanisms and nucleophilic activation by metal coordination in nonenzymatic and ribozyme-catalyzed phosphodiester hydrolysis.

  Biochemistry 20040817

• Modified bases in RNA reduce secondary structure and enhance hybridization.

  Biochemistry 20040810

• [Treatment of chronic hepatitis C].

  Orvosi hetilap 20040808

• A direct, efficient method for the preparation of n6-protected 15n-labeled adenosines.

  The Journal of organic chemistry 20040806

• Influence of minor groove substituents on the structure of DNA Holliday junctions.

  Biochemistry 20040803

• Systematic identification of abundant A-to-I editing sites in the human transcriptome.

  Nature biotechnology 20040801

• Uridine release during aminopyridine-induced epilepsy.

  Neurobiology of disease 20040801

• Type 2 diabetes and the genetics of signal transduction: a study of interaction between adenosine deaminase and acid phosphatase locus 1 polymorphisms.

  Metabolism: clinical and experimental 20040801

• Editing the message from A to I.

  Nature biotechnology 20040801

• In vitro adenine nucleotide catabolism in African catfish spermatozoa.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20040801

• Energostim in therapy of chronic ischemia of the lower limbs.

  Bulletin of experimental biology and medicine 20040801

• The nucleoside derivative 5'-O-trityl-inosine (KIN59) suppresses thymidine phosphorylase-triggered angiogenesis via a noncompetitive mechanism of action.

  The Journal of biological chemistry 20040709

• Adenosine down-regulates the surface expression of dipeptidyl peptidase IV on HT-29 human colorectal carcinoma cells: implications for cancer cell behavior.

  The American journal of pathology 20040701

• Efficiency of refracterin in patients with chronic cardiac insufficiency caused by coronary heart disease.

  Bulletin of experimental biology and medicine 20040701

• Plasma purine nucleoside phosphorylase in cancer patients.

  Clinica chimica acta; international journal of clinical chemistry 20040601

• Controllable regioselective enzymatic synthesis of polymerizable 5'-O-vinyl- and 3'-O-vinyl-nucleoside analogues in acetone.

  Biotechnology letters 20040601

• [Inhibition of adenosine deaminase activity by drugs influencing the cardiovascular system].

  Polskie Archiwum Medycyny Wewnetrznej 20040601

• Benzamide riboside induced mitochondrial mediated apoptosis in human lung cancer H520 cells.

  Life sciences 20040528

• Mutation of leucine-92 selectively reduces the apparent affinity of inosine, guanosine, NBMPR [S6-(4-nitrobenzyl)-mercaptopurine riboside] and dilazep for the human equilibrative nucleoside transporter, hENT1.

  The Biochemical journal 20040515

• Differential inhibition of adenylyl cyclase isoforms and soluble guanylyl cyclase by purine and pyrimidine nucleotides.

  The Journal of biological chemistry 20040507

• Generic detection and differentiation of tobamoviruses by a spot nested RT-PCR-RFLP using dI-containing primers along with homologous dG-containing primers.

  Journal of virological methods 20040501

• Presynaptic inhibition of spontaneous acetylcholine release induced by adenosine at the mouse neuromuscular junction.

  British journal of pharmacology 20040501

• Structures of two RNA octamers containing tandem G.A base pairs.

  Acta crystallographica. Section D, Biological crystallography 20040501

• Nucleotides in sow colostrum and milk at different stages of lactation.

  Journal of animal science 20040501

• Variation of the spore population of a natural source strain of Bacillus cereus in the presence of inosine.

  Journal of food protection 20040501

• Improving the pyrophosphate-inosine phosphotransferase activity of Escherichia blattae acid phosphatase by sequential site-directed mutagenesis.

  Bioscience, biotechnology, and biochemistry 20040501

• [Clinical observation on prevention of 'jia wei si jun zi tang' from damage of hepatic reserving function after intervention of liver cancer].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20040501

• Altered RNA editing of serotonin 5-HT2C receptor induced by interferon: implications for depression associated with cytokine therapy.

  Brain research. Molecular brain research 20040429

• Inosine 5'-monophosphate dehydrogenase binds nucleic acids in vitro and in vivo.

  The Biochemical journal 20040415

• Inosine stimulates chemotaxis, Ca2+-transients and actin polymerization in immature human dendritic cells via a pertussis toxin-sensitive mechanism independent of adenosine receptors.

  Journal of cellular physiology 20040401

• Inhibitory effect of pyrimidine and purine nucleotides on the multiplication of Babesia gibsoni: possible cause of low parasitemia and simultaneous reticulocytosis in canine babesiosis.

  The Journal of veterinary medical science 20040401

• Inosine reverses the inhibitory effects of the L-type Ca2+ channel antagonist, DM-BODIPY-dihydropyridine, on neuritogenesis in an in vitro rat superior cervical ganglia axotomy model.

  Neuroscience letters 20040325

• The biological activity in mammals and insects of the nucleosidic fraction from the spider Parawixia bistriata.

  Toxicon : official journal of the International Society on Toxinology 20040315

• Structures of purine 2'-deoxyribosyltransferase, substrate complexes, and the ribosylated enzyme intermediate at 2.0 A resolution.

  Biochemistry 20040309

• Allelic variation of the Tas1r3 taste receptor gene selectively affects behavioral and neural taste responses to sweeteners in the F2 hybrids between C57BL/6ByJ and 129P3/J mice.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20040303

• In Saccharomyces cerevisiae, the effect of H2O2 on ATP, but not on glyceraldehyde-3-phosphate dehydrogenase, depends on the glucose concentration.

  Archives of microbiology 20040301

• Functional group recognition at the aminoacylation and editing sites of E. coli valyl-tRNA synthetase.

  RNA (New York, N.Y.) 20040301

• Stimulus- and cell-type-specific release of purines in cultured rat forebrain astrocytes and neurons.

  Journal of neurochemistry 20040301

• Immunomodulatory and neuroprotective effects of inosine.

  Trends in pharmacological sciences 20040301

• Future trends in managing hepatitis C.

  Gastroenterology clinics of North America 20040301

• Metabolic characteristics of experimental free vascularized canine gracilis muscle transfers.

  Plastic and reconstructive surgery 20040301

• Purine nucleosides support the neurite outgrowth of primary rat cerebellar granule cells after hypoxia.

  European journal of cell biology 20040301

• Position-specific suppression and enhancement of HIV-1 integrase reactions by minor groove benzo[a]pyrene diol epoxide deoxyguanine adducts: implications for molecular interactions between integrase and substrates.

  The Journal of biological chemistry 20040227

• Transition state analysis for human and Plasmodium falciparum purine nucleoside phosphorylases.

  Biochemistry 20040217

• Stress-induced apoptosis associated with null mutation of ADAR1 RNA editing deaminase gene.

  The Journal of biological chemistry 20040206

• Structure and sequence determinants required for the RNA editing of ADAR2 substrates.

  The Journal of biological chemistry 20040206

• Interstitial purine metabolites in hearts with LV remodeling.

  American journal of physiology. Heart and circulatory physiology 20040201

• A microtiter fluorometric assay to detect the germination of Bacillus anthracis spores and the germination inhibitory effects of antibodies.

  Journal of microbiological methods 20040201

• Neuroprotective effect of inosine on axotomized retinal ganglion cells in adult rats.

  Investigative ophthalmology & visual science 20040201

• Identification of proteins in the exosporium of Bacillus anthracis.

  Microbiology (Reading, England) 20040201

• Efficacy of intramuscular matrine in the treatment of chronic hepatitis B.

  Hepatobiliary & pancreatic diseases international : HBPD INT 20040201

• Glycine 154 of the equilibrative nucleoside transporter, hENT1, is important for nucleoside transport and for conferring sensitivity to the inhibitors nitrobenzylthioinosine, dipyridamole, and dilazep.

  Biochemical pharmacology 20040201

• Structures of human purine nucleoside phosphorylase complexed with inosine and ddI.

  Biochemical and biophysical research communications 20040123

• Substitution reactions of [Pt(terpy)X]2+ with some biologically relevant ligands. Synthesis and crystal structure of [Pt(terpy)(cyst-S)](ClO4)2.0.5H2O and [Pt(terpy)(guo-N7)](ClO4)2.0.5guo.1.5H2O.

  Dalton transactions (Cambridge, England : 2003) 20040121

• p53-independent induction of p21(waf1/cip1) contributes to the activation of caspases in GTP-depletion-induced apoptosis of insulin-secreting cells.

  Cell death and differentiation 20040101

• Regulation of adenosine receptor engagement by ecto-adenosine deaminase.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040101

• Transport of physiological nucleosides and anti-viral and anti-neoplastic nucleoside drugs by recombinant Escherichia coli nucleoside-H(+) cotransporter (NupC) produced in Xenopus laevis oocytes.

  Molecular membrane biology 20040101

• Metabolic changes induced by ischemia and cardioplegia: a study employing cardiac microdialysis in pigs.

  European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20040101

• Comparison of the effect of water release on the interaction of the Saccharomyces cerevisiae TATA binding protein (TBP) with 'TATA Box' sequences composed of adenosine or inosine.

  Biophysical journal 20040101

• Adenosine deaminases acting on RNA (ADARs): RNA-editing enzymes.

  Genome biology 20040101

• Inosine alleviates rat caerulein pancreatitis and pancreatitis-associated lung injury.

  Journal of gastroenterology 20040101

• Effect of inosine on pancreatitis: a powerful tool?

  Journal of gastroenterology 20040101

• Methods for the analysis of adenosine-to-inosine editing in RNA.

  Methods in molecular biology (Clifton, N.J.) 20040101

• Extracellular inosine is modulated by H2O2 and protects sertoli cells against lipoperoxidation and cellular injury.

  Free radical research 20040101

• Synthesis and evaluation of ATP-binding site directed potential inhibitors of nucleoside triphosphatases/helicases and polymerases of hepatitis C and other selected Flaviviridae viruses.

  Antiviral chemistry & chemotherapy 20040101

• Identification of substrates for adenosine deaminases that act on RNA.

  Methods in molecular biology (Clifton, N.J.) 20040101

• [Cardioprotective effect of energostim in toxic allergic myocarditis].

  Eksperimental'naia i klinicheskaia farmakologiia 20040101

• A multi-scale study of industrial fermentation processes and their optimization.

  Advances in biochemical engineering/biotechnology 20040101

• Differences in intramembrane particle distribution in young and old human erythrocytes.

  Cell biology international 20040101

• Mycophenolate mofetil in multiple sclerosis.

  Clinical neuropharmacology 20040101

• Enzyme activities controlling adenosine levels in normal and neoplastic tissues.

  Medical oncology (Northwood, London, England) 20040101

• Complete genome sequence of the industrial bacterium Bacillus licheniformis and comparisons with closely related Bacillus species.

  Genome biology 20040101

• Analysis of urinary nucleosides. IV. Identification of urinary purine nucleosides by liquid chromatography/electrospray mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20040101

• Mechanism of ganciclovir uptake by rabbit retina and human retinal pigmented epithelium cell line ARPE-19.

  Current eye research 20040101

• Phylogenomic evidence supports past endosymbiosis, intracellular and horizontal gene transfer in Cryptosporidium parvum.

  Genome biology 20040101

• [Immunomodulating activity of polyunsaturated phospholipids and regulators of energy metabolism in toxic anemia].

  Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20040101

• Mollusk-derived growth factor and the new subfamily of adenosine deaminase-related growth factors.

  Current pharmaceutical design 20040101

• Intracoronary angiotensin II causes inotropic and vascular effects via different paracrine mechanisms.

  Vascular pharmacology 20040101

• Analyses of PCR products using DNA templates containing a consecutive deoxyinosine sequence.

  Nucleic acids symposium series (2004) 20040101

• Differential requirement for A2a and A3 adenosine receptors for the protective effect of inosine in vivo.

  Blood 20031215

• Thermodynamic stability and structural features of the J4/5 loop in a Pneumocystis carinii group I intron.

  Biochemistry 20031209

• Dominant localization of adenosine deaminase in leptomeninges and involvement of the enzyme in sleep.

  Biochemical and biophysical research communications 20031205

• Extracellular adenine nucleotides metabolism in astrocyte cultures from different brain regions.

  Neurochemistry international 20031201

• Contraction-mediated glycogenolysis in mouse skeletal muscle lacking creatine kinase: the role of phosphorylase b activation.

  The Journal of physiology 20031201

• Effects of base substitutions in an RNA hairpin from molecular dynamics and free energy simulations.

  Biophysical journal 20031201

• Changes in adenosine transport associated with melaminophenyl arsenical (Mel CY) resistance in Trypanosoma evansi: down-regulation and affinity changes of the P2 transporter.

  Parasitology 20031201

• Serum from dogs Infected with Babesia gibsoni inhibits maturation of reticulocytes and erythrocyte 5'-nucleotidase activity in vitro.

  The Journal of veterinary medical science 20031201

• RNA editing and alternative splicing of human serotonin 2C receptor in schizophrenia.

  Journal of neurochemistry 20031201

• [Structure identification of jujuboside E].

  Yao xue xue bao = Acta pharmaceutica Sinica 20031201

• Inhibition of caffeine biosynthesis in tea (Camellia sinensis) and coffee (Coffea arabica) plants by ribavirin.

  FEBS letters 20031120

• Intracellular localization of differentially regulated RNA-specific adenosine deaminase isoforms in inflammation.

  The Journal of biological chemistry 20031114

• Effects of rejuvenation and frozen storage on 42-day-old AS-3 RBCs.

  Transfusion 20031101

• Mechanisms of apoptosis in developing thymocytes as revealed by adenosine deaminase-deficient fetal thymic organ cultures.

  Biochemical pharmacology 20031015

• DNA sequence recognition by bispyrazinonaphthalimides antitumor agents.

  Biochemistry 20031014

• Aplysia mollusk-derived growth factor is a mitogen with adenosine deaminase activity and is expressed in the developing central nervous system.

  Brain research. Molecular brain research 20031007

• An unspecific immunostimulating agent and juvenile dermatomyositis: enhanced T-cell proliferation and reverse immunosuppression as a severe adverse drug reaction.

  European journal of pediatrics 20031001

• Methods for the design and analysis of oligodeoxynucleotide-based DNA (cytosine-5) methyltransferase inhibitors.

  Analytical biochemistry 20031001

• Detection of achondroplasia G380R mutation from PCR amplicons by using inosine modified carbon electrodes based on electrochemical DNA chip technology.

  Clinica chimica acta; international journal of clinical chemistry 20031001

• Mechanisms of arsenical and diamidine uptake and resistance in Trypanosoma brucei.

  Eukaryotic cell 20031001

• Aging-related changes in myocardial purine metabolism and ischemic tolerance.

  Experimental gerontology 20031001

• Effect of mycophenolate mofetil on IMP dehydrogenase after the first dose and after long-term treatment in renal transplant recipients.

  International journal of clinical pharmacology and therapeutics 20031001

• Equilibrative nucleoside transporter family members from Leishmania donovani are electrogenic proton symporters.

  The Journal of biological chemistry 20030912

• Effects of purine nucleosides on the in vitro growth of Cryptosporidium parvum.

  FEMS microbiology letters 20030912

• Oviduct cells express the cyclic AMP-adenosine pathway.

  Biology of reproduction 20030901

• Purine and pyrimidine metabolites in children's urine.

  Clinica chimica acta; international journal of clinical chemistry 20030901

• Allopurinol improves cardiac dysfunction after ischemia-reperfusion via reduction of oxidative stress in isolated perfused rat hearts.

  Circulation journal : official journal of the Japanese Circulation Society 20030901

• Validity of the microdialysis technique for experimental in vivo studies of myocardial energy metabolism.

  Acta physiologica Scandinavica 20030901

• High-resolution real-time recording with microelectrode biosensors reveals novel aspects of adenosine release during hypoxia in rat hippocampal slices.

  Journal of neurochemistry 20030901

• Carbocyclic analogues of nucleosides from bis-(Hydroxymethyl)-cyclopentane: synthesis, antiviral and cytostatic activities of adenosine, inosine and uridine analogues.

  Chemical & pharmaceutical bulletin 20030901

• Absence of 2'-deoxyoxanosine and presence of abasic sites in DNA exposed to nitric oxide at controlled physiological concentrations.

  Chemical research in toxicology 20030901

• Extracellular nucleotides and nucleosides induce proliferation and increase nucleoside transport in human glioma cell lines.

  Journal of neuro-oncology 20030901

• Effect of richlocaine alone or in combination with energostim on the severity of endotoxemia and survival of the skin under conditions of reduced blood flow.

  Bulletin of experimental biology and medicine 20030901

• Morphological study of reparative processes in the gingiva during therapy of chronic periodontitis with energostim and application of orthopedic splinting constructions.

  Bulletin of experimental biology and medicine 20030901

• [Distinctive compound in Rhizome of Pinellia ternata].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20030901

• Functional analysis of an inosine-guanosine transporter from Leishmania donovani. The role of conserved residues, aspartate 389 and arginine 393.

  The Journal of biological chemistry 20030829

• Phosphorylation and dephosphorylation of polyhydroxy compounds by class A bacterial acid phosphatases.

  Organic & biomolecular chemistry 20030821

• Use of a three-dimensional in vitro model of the rat blood-brain barrier to assay nucleoside efflux from brain.

  Brain research 20030808

• Nervous system targets of RNA editing identified by comparative genomics.

  Science (New York, N.Y.) 20030808

• Design of base-discriminating fluorescent nucleoside and its application to t/c SNP typing.

  Journal of the American Chemical Society 20030806

• T cell immunostimulation by methyl inosine 5'-monophosphate: application to infectious diseases.

  International immunopharmacology 20030801

• Use of nucleotide analogs by class I and class II CCA-adding enzymes (tRNA nucleotidyltransferase): deciphering the basis for nucleotide selection.

  RNA (New York, N.Y.) 20030801

• Functional expression and characterization of a sodium-dependent nucleoside transporter hCNT2 cloned from human duodenum.

  Biochemical and biophysical research communications 20030801

• Effects of high frequency electrical stunning and decapitation on early rigor development and meat quality of broiler breast meat.

  Poultry science 20030801

• Identification and characterisation of high affinity nucleoside and nucleobase transporters in Toxoplasma gondii.

  International journal for parasitology 20030730

• Reversed-phase liquid chromatography on an amide stationary phase for the determination of the B group vitamins in baby foods.

  Journal of chromatography. A 20030725

• Modulation of the skeletal muscle Ca2+ release channel/ryanodine receptor by adenosine and its metabolites: a structure-activity approach.

  Bioorganic & medicinal chemistry 20030703

• Arsenate reduction in human erythrocytes and rats--testing the role of purine nucleoside phosphorylase.

  Toxicological sciences : an official journal of the Society of Toxicology 20030701

• Gene expression patterns as potential molecular biomarkers for malignant transformation in human keratinocytes treated with MNNG, arsenic, or a metal mixture.

  Toxicological sciences : an official journal of the Society of Toxicology 20030701

• Role of IMP-selective 5'-nucleotidase (cN-II) in hematological malignancies.

  Leukemia & lymphoma 20030701

• Cloning, heterologous expression, and in situ characterization of the first high affinity nucleobase transporter from a protozoan.

  The Journal of biological chemistry 20030627

• Unexpected inhibition of S-adenosyl-L-homocysteine hydrolase by a guanosine nucleoside.

  Bioorganic & medicinal chemistry letters 20030616

• Molecular cloning of an unusual bicistronic cholecystokinin receptor mRNA expressed in chicken brain: a structural and functional expression study.

  Regulatory peptides 20030615

• ATP inhibits NMDA receptors after heterologous expression and in cultured hippocampal neurons and attenuates NMDA-mediated neurotoxicity.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20030615

• Rapid radical formation by DNA charge transport through sequences lacking intervening guanines.

  Journal of the American Chemical Society 20030604

• Effects of diadenosine polyphosphates and seminal fluid vesicles on rabbit sperm cells.

  Reproduction (Cambridge, England) 20030601

• Ischaemic preconditioning alters the energy metabolism and protects the ischaemic myocardium in a stepwise fashion.

  Acta physiologica Scandinavica 20030601

• Microdialysis-evaluated myocardial cyclooxygenase-mediated inflammation and early circulatory depression in porcine endotoxemia.

  Critical care medicine 20030601

• Functional characterization of a H+/nucleoside co-transporter (CaCNT) from Candida albicans, a fungal member of the concentrative nucleoside transporter (CNT) family of membrane proteins.

  Yeast (Chichester, England) 20030601

• Adenosine-mediated early preconditioning in mouse: protective signaling and concentration dependent effects.

  Cardiovascular research 20030601

• Allantoin, the oxidation product of uric acid is present in chicken and turkey plasma.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20030601

• Relationship between gluconeogenesis and glutathione redox state in rabbit kidney-cortex tubules.

  Metabolism: clinical and experimental 20030601

• Taste perception with age: generic or specific losses in supra-threshold intensities of five taste qualities?

  Chemical senses 20030601

• [Relationship between key enzyme activities of inosine-producing pathway and inosine accumulation].

  Wei sheng wu xue bao = Acta microbiologica Sinica 20030601

• Over-the-barrier transition state analogues and crystal structure with Mycobacterium tuberculosis purine nucleoside phosphorylase.

  Biochemistry 20030527

• Dynamic association of RNA-editing enzymes with the nucleolus.

  Journal of cell science 20030501

• Widespread inosine-containing mRNA in lymphocytes regulated by ADAR1 in response to inflammation.

  Immunology 20030501

• Using fructose-1,6-diphosphate during hypothermic rabbit-heart preservation: a high-energy phosphate study.

  The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20030501

• Effects of inosine on axonal regeneration of axotomized retinal ganglion cells in adult rats.

  Neuroscience letters 20030424

• A colorimetric assay for inorganic pyrophosphate that is also useful for measuring product accumulation in polymerase chain reactions.

  Analytical biochemistry 20030415

• H2O2, but not menadione, provokes a decrease in the ATP and an increase in the inosine levels in Saccharomyces cerevisiae. An experimental and theoretical approach.

  European journal of biochemistry 20030401

• Purification and characterization of 5'-methylthioadenosine phosphorylase from the hyperthermophilic archaeon Pyrococcus furiosus: substrate specificity and primary structure analysis.

  Extremophiles : life under extreme conditions 20030401

• Ischemic preconditioning does not improve myocardial preservation during off-pump multivessel coronary operation.

  The Annals of thoracic surgery 20030401

• Intravenous and oral pharmacokinetic study of BCX-1777, a novel purine nucleoside phosphorylase transition-state inhibitor. In vivo effects on blood 2'-deoxyguanosine in primates.

  International immunopharmacology 20030401

• Voltammetric and impedance studies of inosine-5'-monophosphate and hypoxanthine.

  Bioelectrochemistry (Amsterdam, Netherlands) 20030401

• The purine nucleoside cycle in cell-free extracts of rat brain: evidence for the occurrence of an inosine and a guanosine cycle with distinct metabolic roles.

  Cellular and molecular life sciences : CMLS 20030401

• Intraocular adenosine levels in normal and ocular-hypertensive patients.

  Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20030401

• Mapping interactions between the Ca2+-ATPase and its substrate ATP with infrared spectroscopy.

  The Journal of biological chemistry 20030321

• Polyethylene glycol-conjugated adenosine phosphorylase: development of alternative enzyme therapy for adenosine deaminase deficiency.

  Biochimica et biophysica acta 20030320

• Cardiac outflow of amino acids and purines during myocardial ischemia and reperfusion.

  Journal of applied physiology (Bethesda, Md. : 1985) 20030301

• Neuron-specific enolase, nucleotides, nucleosides, purine bases, oxypurines and uric acid concentrations in cerebrospinal fluid of children with meningitis.

  Brain & development 20030301

• Coordination of editing and splicing of glutamate receptor pre-mRNA.

  RNA (New York, N.Y.) 20030301

• Na+ gradient-dependent transport of hypoxanthine by calf intestinal brush border membrane vesicles.

  Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20030301

• The effect of lead ions on the energy metabolism of human erythrocytes in vitro.

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20030301

• Extracellular purines from cells of seminiferous tubules.

  Molecular and cellular biochemistry 20030301

• Zusanli point injection for treating leukopenia induced by radio-chemotherapy.

  Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 20030301

• Structural properties of the neutral and monoanionic forms of xanthosine, highly relevant to their substrate properties with various enzyme systems.

  Nucleosides, nucleotides & nucleic acids 20030301

• Adenosine suppresses activation of nuclear factor-kappaB selectively induced by tumor necrosis factor in different cell types.

  Oncogene 20030227

• Factors that contribute to efficient catalytic activity of a small Ca2+-dependent deoxyribozyme in relation to its RNA cleavage function.

  Biochemistry 20030225

• Molecular classification of synovial sarcomas, leiomyosarcomas and malignant fibrous histiocytomas by gene expression profiling.

  British journal of cancer 20030224

• 8'-aminoguanosine inclusion results in enhanced efflux of taurine in preconditioned ischemic myocardium.

  Journal of cardiovascular pharmacology 20030201

• Simultaneous determination of purine nucleotides, their metabolites and beta-nicotinamide adenine dinucleotide in cerebellar granule cells by ion-pair high performance liquid chromatography.

  Brain research. Brain research protocols 20030201

• Significance of the non-oxidative route of the pentose phosphate pathway for supplying carbon to the purine-nucleotide pathway in Corynebacterium ammoniagenes.

  Journal of industrial microbiology & biotechnology 20030201

• A-to-I RNA editing: recent news and residual mysteries.

  The Journal of biological chemistry 20030117

• Intrinsic acid-base properties of purine derivatives in aqueous solution and comparison of the acidifying effects of platinum(II) coordinated to N1 or N7: acidifying effects are reciprocal and the proton 'outruns' divalent metal ions.

  Inorganic chemistry 20030113

• Highly selective binding of organometallic ruthenium ethylenediamine complexes to nucleic acids: novel recognition mechanisms.

  Journal of the American Chemical Society 20030108

• 8-Aza-immucillins as transition-state analogue inhibitors of purine nucleoside phosphorylase and nucleoside hydrolases.

  Journal of medicinal chemistry 20030102

• A new and efficient strategy for the synthesis of shimofuridin analogs: 2'-O-(4-O-stearoyl-alpha-L-fucopyranosyl)thymidine and -uridine.

  Carbohydrate research 20030102

• Inosine reduces inflammation and improves survival in a murine model of colitis.

  American journal of physiology. Gastrointestinal and liver physiology 20030101

• The salivary purine nucleosidase of the mosquito, Aedes aegypti.

  Insect biochemistry and molecular biology 20030101

• Variability in spore germination response by strains of proteolytic Clostridium botulinum types A, B and F.

  Letters in applied microbiology 20030101

• Mycophenolic acid inhibits inosine 5'-monophosphate dehydrogenase and suppresses immunoglobulin and cytokine production of B cells.

  International immunopharmacology 20030101

• Signaling and regulation of G protein-coupled receptors in airway smooth muscle.

  Respiratory research 20030101

• Gene expression profile of AIDS-related Kaposi's sarcoma.

  BMC cancer 20030101

• The gene structure and expression of human ABHD1: overlapping polyadenylation signal sequence with Sec12.

  BMC genomics 20030101

• The yeast ISN1 (YOR155c) gene encodes a new type of IMP-specific 5'-nucleotidase.

  BMC biochemistry 20030101

• Hepatitis C virus therapies: current treatments, targets and future perspectives.

  Antiviral chemistry & chemotherapy 20030101

• Functional expression of a sodium dependent nucleoside transporter on rabbit cornea: Role in corneal permeation of acyclovir and idoxuridine.

  Current eye research 20030101

• Inosine protects against the development of diabetes in multiple-low-dose streptozotocin and nonobese diabetic mouse models of type 1 diabetes.

  Molecular medicine (Cambridge, Mass.) 20030101

• Glutamine administration during total parenteral nutrition protects liver adenosine nucleotides during and after subsequent hemorrhagic shock.

  JPEN. Journal of parenteral and enteral nutrition 20030101

• Direct sequencing with highly degenerate and inosine-containing primers.

  Methods in molecular biology (Clifton, N.J.) 20030101

• Clear distinction of pyrimidine bases on the complementary strand by fluorescence change of novel fluorescent nucleosides.

  Nucleic acids research. Supplement (2001) 20030101

• [Papules on the dorsal interphalangeal joints and an unspecific immunostimulating agent].

  Klinische Padiatrie 20030101

• 5'-O-fluorosulfonylbenzoyl esters of purine nucleosides as potential inhibitors of NTPase/helicase and polymerase of Flaviviridae viruses.

  Nucleosides, nucleotides & nucleic acids 20030101

• Hydrolytic cleavage of purine ribonucleosides in Aspergillus phoenicis.

  Journal of basic microbiology 20030101

• [Effect of energostim on myocardial damage during coronary artery occlusion].

  Eksperimental'naia i klinicheskaia farmakologiia 20030101

• Multivariate metabolic profiling using 1H nuclear magnetic resonance spectroscopy of freeze-tolerant and freeze-intolerant earthworms exposed to frost.

  Cryo letters 20030101

• Purification and characterization of fructose bisphosphate aldolase from the ground squirrel, Spermophilus lateralis: enzyme role in mammalian hibernation.

  Archives of biochemistry and biophysics 20021215

• Exploring nucleoside hydrolase catalysis in silico: molecular dynamics study of enzyme-bound substrate and transition state.

  Journal of the American Chemical Society 20021211

• Equilibrative and concentrative nucleoside transporters mediate influx of extracellular cyclic ADP-ribose into 3T3 murine fibroblasts.

  The Journal of biological chemistry 20021206

• Site-specific modification of functional groups in genomic hepatitis delta virus (HDV) ribozyme.

  European journal of biochemistry 20021201

• Mycophenolate mofetil in combination with recombinant interferon alfa-2a in interferon-nonresponder patients with chronic hepatitis C.

  Journal of hepatology 20021201

• Glucose, insulin and potassium (GIK) during reperfusion mediates improved myocardial bioenergetics.

  Resuscitation 20021201

• Mutagenic spectrum of butadiene-derived N1-deoxyinosine adducts and N6,N6-deoxyadenosine intrastrand cross-links in mammalian cells.

  Chemical research in toxicology 20021201

• Cardiac surgery: myocardial energy balance, antioxidant status and endothelial function after ischemia-reperfusion.

  Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20021201

• Syntheses and calcium-mobilizing evaluations of N1-glycosyl-substituted stable mimics of cyclic ADP-ribose.

  Journal of medicinal chemistry 20021121

• 2-Aminopurine: a probe of structural dynamics and charge transfer in DNA and DNA:RNA hybrids.

  Journal of the American Chemical Society 20021106

• Crystal structure of a ternary complex of Tritrichomonas foetus inosine 5'-monophosphate dehydrogenase: NAD+ orients the active site loop for catalysis.

  Biochemistry 20021105

• The activities of serum adenosine deaminase and xanthine oxidase enzymes in Behcet's disease.

  Clinica chimica acta; international journal of clinical chemistry 20021101

• Reduction of arsenate to arsenite in hepatic cytosol.

  Toxicological sciences : an official journal of the Society of Toxicology 20021101

• Purine nucleoside phosphorylase as a cytosolic arsenate reductase.

  Toxicological sciences : an official journal of the Society of Toxicology 20021101

• Future therapy of hepatitis C.

  Hepatology (Baltimore, Md.) 20021101

• Inosine modulates gut barrier dysfunction and end organ damage in a model of ischemia-reperfusion injury.

  The Journal of surgical research 20021101

• Induction of protein translation by ADAR1 within living cell nuclei is not dependent on RNA editing.

  Molecular cell 20021101

• Ribonucleic acid hydrolysis by intestinal explants of neonatal piglets.

  Journal of pediatric gastroenterology and nutrition 20021101

• Sequence requirements in the catalytic core of the '10-23' DNA enzyme.

  The Journal of biological chemistry 20021025

• Novel amide-based inhibitors of inosine 5'-monophosphate dehydrogenase.

  Bioorganic & medicinal chemistry letters 20021021

• Characterization of the cAMP binding site of purified S-adenosyl-homocysteine hydrolase from bovine kidney.

  Biochemical pharmacology 20021015

• Adenosine to inosine editing by ADAR2 requires formation of a ternary complex on the GluR-B R/G site.

  The Journal of biological chemistry 20021004

• Rapid adenosine release in the nucleus tractus solitarii during defence response in rats: real-time measurement in vivo.

  The Journal of physiology 20021001

• Adenosine release in nucleus tractus solitarii does not appear to mediate hypoxia-induced respiratory depression in rats.

  The Journal of physiology 20021001

• Taste enhancements between various amino acids and IMP.

  Chemical senses 20021001

• Differences between rat primary cortical neurons and astrocytes in purine release evoked by ischemic conditions.

  Neuropharmacology 20021001

• Staphylococcus succinus subsp. casei subsp. nov., a dominant isolate from a surface ripened cheese.

  Systematic and applied microbiology 20021001

• Determination of monophosphate nucleotides by capillary electrophoresis inductively coupled plasma mass spectrometry.

  The Analyst 20021001

• Factors influencing conformer equilibria in retro models of cisplatin-DNA adducts as revealed by moderately dynamic (N,N'-dimethyl-2,3-diaminobutane)PtG(2) retro models (G = a guanine derivative).

  Inorganic chemistry 20020923

• Evaluation of 2-deoxy-D-glucose as a chemotherapeutic agent: mechanism of cell death.

  British journal of cancer 20020923

• Transcript mutations of the alpha regulatory subunit of protein kinase A and up-regulation of the RNA-editing gene transcript in lupus T lymphocytes.

  Lancet (London, England) 20020914

• The neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine induces apoptosis in mouse nigrostriatal glia. Relevance to nigral neuronal death and striatal neurochemical changes.

  The Journal of biological chemistry 20020913

• Smaller muscle ATP reduction in women than in men by repeated bouts of sprint exercise.

  Journal of applied physiology (Bethesda, Md. : 1985) 20020901

• Characterization of pharmacological efficacy of VX-148, a new, potent immunosuppressive inosine 5'-monophosphate dehydrogenase inhibitor.

  The Journal of pharmacology and experimental therapeutics 20020901

• Mycophenolic acid inhibits IL-2-dependent T cell proliferation, but not IL-2-dependent survival and sensitization to apoptosis.

  Journal of immunology (Baltimore, Md. : 1950) 20020901

• [PFAPA Syndrome: Current Standard of Knowledge and Relevance for the ENT Specialist].

  Laryngo- rhino- otologie 20020901

• The cryptic adenine deaminase gene of Escherichia coli. Silencing by the nucleoid-associated DNA-binding protein, H-NS, and activation by insertion elements.

  The Journal of biological chemistry 20020830

• The purine nucleoside phosphorylase from Trichomonas vaginalis is a homologue of the bacterial enzyme.

  Biochemistry 20020820

• Purinergic regulation of glucose and glutamine synthesis in isolated rabbit kidney-cortex tubules.

  Archives of biochemistry and biophysics 20020815

• Specificity of human and rat orthologs of the concentrative nucleoside transporter, SPNT.

  American journal of physiology. Renal physiology 20020801

• Extreme pathway analysis of human red blood cell metabolism.

  Biophysical journal 20020801

• Plasma and cellular pharmacology of 8-chloro-adenosine in mice and rats.

  Cancer chemotherapy and pharmacology 20020801

• Permeability of Coxiella burnetii to ribonucleosides.

  Microbiology (Reading, England) 20020801

• Xanthosine and xanthine. Substrate properties with purine nucleoside phosphorylases, and relevance to other enzyme systems.

  European journal of biochemistry 20020801

• Pericardial concentrations of adenosine, inosine and hypoxanthine in an experimental canine model of spastic ischaemia.

  Clinical science (London, England : 1979) 20020801

• Cyclosporin A and FK506 decrease adenosine kinase activity and adenosine uptake in T-lymphocytes.

  The Journal of laboratory and clinical medicine 20020801

• Purine metabolism and release during cardioprotection with hyperkalemia and hypothermia.

  Molecular and cellular biochemistry 20020801

• RNA editing by adenosine deaminases generates RNA and protein diversity.

  Biochimie 20020801

• Physiological and structural events post mortem of importance for drip loss in pork.

  Meat science 20020801

• Allosteric activation of cGMP-specific, cGMP-binding phosphodiesterase (PDE5) by cGMP.

  Biochemistry 20020730

• Structures of HO(2)-Co(III)bleomycin A(2) bound to d(GAGCTC)(2) and d(GGAAGCTTCC)(2): structure-reactivity relationships of Co and Fe bleomycins.

  Journal of inorganic biochemistry 20020725

• tadA, an essential tRNA-specific adenosine deaminase from Escherichia coli.

  The EMBO journal 20020715

• DNA sequence recognition by the antitumor drug ditercalinium.

  Biochemistry 20020709

• Cytotoxicity and cellular differentiation activity of methylenebis(phosphonate) analogs of tiazofurin and mycophenolic acid adenine dinucleotide in human cancer cell lines.

  Cancer letters 20020708

• Formation of sulfur aroma compounds in reaction mixtures containing cysteine and three different forms of ribose.

  Journal of agricultural and food chemistry 20020703

• A-to-I editing: new and old sites, functions and speculations.

  Neuron 20020703

• Mutational analysis of endonuclease V from Thermotoga maritima.

  Biochemistry 20020702

• Effects of different oxidizing agents on neutral amino acid transport systems in isolated bovine brain microvessels.

  Neurochemistry international 20020701

• An ancient prevertebrate Na+-nucleoside cotransporter (hfCNT) from the Pacific hagfish (Eptatretus stouti).

  American journal of physiology. Cell physiology 20020701

• Crystal structures of free, IMP-, and GMP-bound Escherichia coli hypoxanthine phosphoribosyltransferase.

  Protein science : a publication of the Protein Society 20020701

• Germination of Bacillus cereus spores in response to L-alanine and to inosine: the roles of gerL and gerQ operons.

  Microbiology (Reading, England) 20020701

• Amino acid decarboxylase activity and other chemical characteristics as related to freshness loss in iced cod (Gadus morhua).

  Journal of food protection 20020701

• Enhancement of nucleoside phosphorylation activity in an acid phosphatase.

  Protein engineering 20020701

• Molecular recognition by the Candida albicans group I intron: tertiary interactions with an imino G.A pair facilitate binding of the 5' exon and lower the KM for guanosine.

  Biochemistry 20020625

• The kinetic mechanism of the human bifunctional enzyme ATIC (5-amino-4-imidazolecarboxamide ribonucleotide transformylase/inosine 5'-monophosphate cyclohydrolase). A surprising lack of substrate channeling.

  The Journal of biological chemistry 20020621

• 9-[(Hydroxymethyl)phenyl]adenines: new aryladenine substrates of adenosine deaminase.

  Bioorganic & medicinal chemistry letters 20020603

• Purine nucleoside phosphorylase from Cellulomonas sp.: physicochemical properties and binding of substrates determined by ligand-dependent enhancement of enzyme intrinsic fluorescence, and by protective effects of ligands on thermal inactivation of the enzyme.

  Biochimica et biophysica acta 20020603

• Quantification of the influence of mycophenolic acid on the release of endothelial adhesion molecules.

  Clinica chimica acta; international journal of clinical chemistry 20020601

• A product inhibition study on adenosine deaminase by spectroscopy and calorimetry.

  Journal of biochemistry and molecular biology 20020531

• 'Fleximers'. Design and synthesis of a new class of novel shape-modified nucleosides(1).

  The Journal of organic chemistry 20020517

• Enzyme-substrate interactions in the purine-specific nucleoside hydrolase from Trypanosoma vivax.

  The Journal of biological chemistry 20020503

• Flow system for fish freshness determination based on double multi-enzyme reactor electrodes.

  Biosensors & bioelectronics 20020501

• Mechanisms of apoptosis induced by purine nucleosides in astrocytes.

  Glia 20020501

• Calf spleen purine nucleoside phosphorylase: complex kinetic mechanism, hydrolysis of 7-methylguanosine, and oligomeric state in solution.

  Biochimica et biophysica acta 20020429

• Enhanced activation of bound plasminogen on Staphylococcus aureus by staphylokinase.

  FEBS letters 20020424

• Ophidian envenomation strategies and the role of purines.

  Toxicon : official journal of the International Society on Toxinology 20020401

• Influence of mycophenolic acid on inosine 5'-monophosphate dehydrogenase activity in human peripheral blood mononuclear cells.

  Clinica chimica acta; international journal of clinical chemistry 20020401

• Effect of inosine on the plasma concentration of uridine and purine bases.

  Metabolism: clinical and experimental 20020401

• Structure of the 1:1 netropsin-decamer d(CCIICICCII)2 complex with a single bound netropsin.

  Acta crystallographica. Section D, Biological crystallography 20020401

• Inosine exerts a broad range of antiinflammatory effects in a murine model of acute lung injury.

  Annals of surgery 20020401

• Studies on the mechanism of action of benzamide riboside: a novel inhibitor of IMP dehydrogenase.

  Current medicinal chemistry 20020401

• Modulation of cytotoxicity of benzamide riboside by expression of NMN adenylyltransferase.

  Current medicinal chemistry 20020401

• Benzamide riboside, a recent inhibitor of inosine 5'-monophosphate dehydrogenase induces transferrin receptors in cancer cells.

  Current medicinal chemistry 20020401

• Potential mechanisms of benzamide riboside mediated cell death.

  Current medicinal chemistry 20020401

• Antitumor activity of benzamide riboside in vitro and in vivo.

  Current medicinal chemistry 20020401

• Metabolism of the novel IMP dehydrogenase inhibitor benzamide riboside.

  Current medicinal chemistry 20020401

• Participation of yeast inosine 5'-monophosphate dehydrogenase in an in vitro complex with a fragment of the C-rich telomeric strand.

  Biochimie 20020401

• A countermeasure to ameliorate immune dysfunction in in vitro simulated microgravity environment: role of cellularnucleotide nutrition.

  In vitro cellular & developmental biology. Animal 20020401

• Direct protection of inosine on PC12 cells against zinc-induced injury.

  Neuroreport 20020325

• Chemical synthesis and calcium release activity of N(1)-ether strand substituted cADPR mimic.

  Bioorganic & medicinal chemistry letters 20020325

• Biochemical and functional characterization of recombinant Rhodnius prolixus platelet aggregation inhibitor 1 as a novel lipocalin with high affinity for adenosine diphosphate and other adenine nucleotides.

  Biochemistry 20020319

• Structure-activity relationships of 2'-fluoro-2',3'-unsaturated D-nucleosides as anti-HIV-1 agents.

  Journal of medicinal chemistry 20020314

• Manipulation of plasma uric acid in broiler chicks and its effect on leukocyte oxidative activity.

  American journal of physiology. Regulatory, integrative and comparative physiology 20020301

• Enhancement of cellular adenosine triphosphate levels in PC12 cells by extracellular adenosine.

  Biological & pharmaceutical bulletin 20020301

• Anoxia-induced changes in purine nucleoside metabolism of in vitro aged human fibroblasts.

  Life sciences 20020208

• A single glycine mutation in the equilibrative nucleoside transporter gene, hENT1, alters nucleoside transport activity and sensitivity to nitrobenzylthioinosine.

  Biochemistry 20020205

• Specific [(3)H]-guanosine binding sites in rat brain membranes.

  British journal of pharmacology 20020201

• Antitumour and toxic effects on Wistar rats of two new platinum complexes.

  European journal of clinical investigation 20020201

• A mutational analysis of the active site of human type II inosine 5'-monophosphate dehydrogenase.

  Biochimica et biophysica acta 20020131

• The kinetics of hypoxanthine transport across the perfused choroid plexus of the sheep.

  Brain research 20020125

• The efflux of purine nucleobases and nucleosides from the rat brain.

  Neuroscience letters 20020125

• Open and closed conformation of the E. coli purine nucleoside phosphorylase active center and implications for the catalytic mechanism.

  Journal of molecular biology 20020118

• Evidence of an assembly pheromone in the black-legged deer tick, Ixodes scapularis.

  Journal of chemical ecology 20020101

• Detection and subtyping of Herpes simplex virus in clinical samples by LightCycler PCR, enzyme immunoassay and cell culture.

  BMC microbiology 20020101

• Bacterial discrimination by means of a universal array approach mediated by LDR (ligase detection reaction).

  BMC microbiology 20020101

• Mycophenolic acid inhibits inosine 5'-monophosphate dehydrogenase and suppresses production of pro-inflammatory cytokines, nitric oxide, and LDH in macrophages.

  Cellular immunology 20020101

• Inosine stimulates axon growth in vitro and in the adult CNS.

  Progress in brain research 20020101

• NAD+ catabolism in pheochromocytoma rat cells.

  Journal of biological regulators and homeostatic agents 20020101

• [Angiotensin converting enzyme inhibitor enalapril in the treatment of endomyocardial fibrosis in patients with lymphogranulomatosis subjected to radio- and chemotherapy].

  Kardiologiia 20020101

• A Drosophila full-length cDNA resource.

  Genome biology 20020101

• Elevation of antioxidant potency in mice brain by low-dose X-ray irradiation and its effect on Fe-NTA-induced brain damage.

  Physiological chemistry and physics and medical NMR 20020101

• RNAi is antagonized by A-->I hyper-editing.

  EMBO reports 20011215

• Changes in properties of adenosine transporters in Trypanosoma evansi and modes of selection of resistance to the melaminophenyl arsenical drug, Mel Cy.

  Veterinary parasitology 20011213

• Identification and determination of nucleosides in rat brain microdialysates by liquid chromatography/electrospray tandem mass spectrometry.

  Journal of pharmaceutical and biomedical analysis 20011201

• Anti-inflammatory effects of inosine in human monocytes, neutrophils and epithelial cells in vitro.

  International journal of molecular medicine 20011201

• International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors.

  Pharmacological reviews 20011201

• Toxoplasma gondii: mechanism of the parasitostatic action of 6-thioxanthine.

  Experimental parasitology 20011201

• Combination of thymidine phosphorylase gene transfer and deoxyinosine treatment greatly enhances 5-fluorouracil antitumor activity in vitro and in vivo.

  Molecular cancer therapeutics 20011201

• Synthesis of 9-(2,3-dideoxy-2-fluoro-beta-D-threo-pentofuranosyl)adenine (FddA) via a purine 3'-deoxynucleoside.

  The Journal of organic chemistry 20011102

• Formation of 2-chloroinosine from guanosine by treatment of HNO(2) in the presence of NaCl.

  Bioorganic & medicinal chemistry 20011101

• 5'-Adenosine monophosphate and adenosine metabolism, and adenosine responses in mouse, rat and guinea pig heart.

  Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20011101

• Vaccinia virus E3L interferon resistance protein inhibits the interferon-induced adenosine deaminase A-to-I editing activity.

  Virology 20011025

• Mechanism of action of the antitumor agents 6-benzoyl-3,3-disubstituted-1,5-diazabicyclo[3.1.0]hexane-2,4-diones: potent inhibitors of human type II inosine 5'-monophosphate dehydrogenase.

  International journal of cancer 20011015

• Catabolism of exogenous deoxyinosine in cultured epithelial amniotic cells.

  Biochimica et biophysica acta 20011003

• Cardioprotection with adenosine metabolism inhibitors in ischemic-reperfused mouse heart.

  Cardiovascular research 20011001

• Inosine reduces systemic inflammation and improves survival in septic shock induced by cecal ligation and puncture.

  American journal of respiratory and critical care medicine 20011001

• Pre-conditioning activates adenosine utilization in a cost-effective way during myocardial ischaemia.

  Acta physiologica Scandinavica 20011001

• Hamao Umezawa Memorial Award Lecture: 'An Odyssey in the Viral Chemotherapy Field'.

  International journal of antimicrobial agents 20011001

• Inactivation of peroxynitrite in multiple sclerosis patients after oral administration of inosine may suggest possible approaches to therapy of the disease.

  Multiple sclerosis (Houndmills, Basingstoke, England) 20011001

• Non-radioactive determination of inosine 5'-monophosphate dehydro-genase (IMPDH) in peripheral mononuclear cells.

  Clinical biochemistry 20011001

• Cytosolic O-GlcNAc accumulation is not involved in beta-cell death in HIT-T15 or Min6.

  Biochemical and biophysical research communications 20010921

• Stabilities and isomeric equilibria in solutions of monomeric metal-ion complexes of guanosine 5'-triphosphate (GTP4-) and inosine 5'-triphosphate (ITP4-) in comparison with those of adenosine 5'-triphosphate (ATP4-).

  Chemistry (Weinheim an der Bergstrasse, Germany) 20010903

• Early onset of lipid peroxidation after human traumatic brain injury: a fatal limitation for the free radical scavenger pharmacological therapy?

  Journal of investigative medicine : the official publication of the American Federation for Clinical Research 20010901

• In vitro effects of isoprinosine and a dipeptide methyl ester on Echinococcus multilocularis protoscoleces.

  Journal of helminthology 20010901

• Taste perception with age: generic or specific losses in threshold sensitivity to the five basic tastes?

  Chemical senses 20010901

• Profiles of purine and pyrimidine nucleotides in fresh and manufactured tea leaves.

  Journal of agricultural and food chemistry 20010901

• Concentrations of nucleotides, nucleosides, purine bases, oxypurines, uric acid, and neuron-specific enolase in the cerebrospinal fluid of children with sepsis.

  Journal of child neurology 20010901

• Effect of glycerol-induced hyperhydration on thermoregulation and metabolism during exercise in heat.

  International journal of sport nutrition and exercise metabolism 20010901

• Effect of transketolase modifications on carbon flow to the purine-nucleotide pathway in Corynebacterium ammoniagenes.

  Applied microbiology and biotechnology 20010901

• Receptor-mediated interaction between the sympathetic nervous system and immune system in inflammation.

  Neurochemical research 20010901

• Ribavirin: recent insights into antiviral mechanisms of action.

  Current opinion in drug discovery & development 20010901

• The fate of dsRNA in the nucleus: a p54(nrb)-containing complex mediates the nuclear retention of promiscuously A-to-I edited RNAs.

  Cell 20010824

• Pyruvate improves cerebral metabolism during hemorrhagic shock.

  American journal of physiology. Heart and circulatory physiology 20010801

• Induction of Tmolt4 leukemia cell death by 3,3-disubstituted-6,6-pentamethylene-1,5-diazabicyclo[3.1.0]hexane-2-4-diones: specificity for type II inosine 5'-monophasphate dehydrogenase.

  The Journal of pharmacology and experimental therapeutics 20010801

• High adenosine and deoxyadenosine concentrations in mononuclear cells of hemodialyzed patients.

  Journal of the American Society of Nephrology : JASN 20010801

• Inosine attenuates tourniquet-induced skeletal muscle reperfusion injury.

  The Journal of surgical research 20010801

• Specific cleavage of hyper-edited dsRNAs.

  The EMBO journal 20010801

• Determination of the effects of mycophenolic acid on the nucleotide pool of human peripheral blood mononuclear cells in vitro by high-performance liquid chromatography.

  Clinica chimica acta; international journal of clinical chemistry 20010801

• In vitro effects of mycophenolic acid on the nucleotide pool and on the expression of adhesion molecules of human umbilical vein endothelial cells.

  Clinica chimica acta; international journal of clinical chemistry 20010801

• Multiple cleavage activities of endonuclease V from Thermotoga maritima: recognition and strand nicking mechanism.

  Biochemistry 20010731

• Guanosine-induced increase in free cytosolic calcium concentration in mouse astrocytes in primary cultures: does it act on an A3 adenosine receptor?

  Journal of neuroscience research 20010715

• Stereocontrolled syntheses of carbocyclic C-nucleosides and related compounds.

  The Journal of organic chemistry 20010713

• Mollusk-derived growth factor: cloning and developmental expression in the central nervous system and reproductive tract of Aplysia.

  Brain research. Molecular brain research 20010713

• Expression, purification, and characterization of recombinant purine nucleoside phosphorylase from Escherichia coli.

  Protein expression and purification 20010701

• Separation of inosine, hypoxanthine, and guanosine by high-performance liquid chromatography on silica.

  Journal of chromatographic science 20010701

• Chronic ethanol enhances adenosine antiadrenergic actions in the isolated rat heart.

  Alcoholism, clinical and experimental research 20010701

• Intracellular phosphorylation of carbocyclic 3-deazaadenosine, an anti-Ebola virus agent.

  Antiviral chemistry & chemotherapy 20010701

• Factors that modify penicillamine-induced autoimmunity in Brown Norway rats: failure of the Th1/Th2 paradigm.

  Toxicology 20010621

• Synthesis and characterization of oligodeoxynucleotides containing an N1 beta-hydroxyalkyl adduct of 2'-deoxyinosine.

  Chemical research in toxicology 20010601

• Substrate recognition by ADAR1 and ADAR2.

  RNA (New York, N.Y.) 20010601

• The salivary adenosine deaminase activity of the mosquitoes Culex quinquefasciatus and Aedes aegypti.

  The Journal of experimental biology 20010601

• Inosine monophosphate dehydrogenase (IMPDH) inhibition in vitro suppresses lymphocyte proliferation and the production of immunoglobulins, autoantibodies and cytokines in splenocytes from MRLlpr/lpr mice.

  Clinical and experimental immunology 20010601

• F13459, a new derivative of mycophenolic acid. I. Taxonomy, isolation, and biological properties.

  The Journal of antibiotics 20010601

• ADAR1 is involved in the development of microvascular lung injury.

  Circulation research 20010525

• Direct observation of radical intermediates in protein-dependent DNA charge transport.

  Journal of the American Chemical Society 20010516

• Long-range cooperativity in molecular recognition of RNA by oligodeoxynucleotides with multiple C5-(1-propynyl) pyrimidines.

  Journal of the American Chemical Society 20010509

• Dependence of 13C NMR chemical shifts on conformations of rna nucleosides and nucleotides.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20010501

• Genomic clustering of tRNA-specific adenosine deaminase ADAT1 and two tRNA synthetases.

  Mammalian genome : official journal of the International Mammalian Genome Society 20010501

• Adenosine in relation to calcium homeostasis: comparison between gray and white matter ischemia.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20010501

• gsk disruption leads to guanosine accumulation in Escherichia coli.

  Bioscience, biotechnology, and biochemistry 20010501

• Synthesis of N2-substituted deoxyguanosine nucleosides from 2-fluoro-6-O-(trimethylsilylethyl)-2'-deoxyinosine.

  Current protocols in nucleic acid chemistry 20010501

• The kinetics of hypoxanthine efflux from the rat brain.

  Brain research 20010427

• Ligand binding distributions in nucleic acids.

  Biopolymers 20010415

• The invertebrate growth factor/CECR1 subfamily of adenosine deaminase proteins.

  Gene 20010404

• Design and evaluation of PCR primers to amplify bacterial 16S ribosomal DNA fragments used for community fingerprinting.

  Journal of microbiological methods 20010401

• Ascorbic acid changes the pattern of purine metabolism during germination of white spruce somatic embryos.

  Tree physiology 20010401

• Effect of rejuvenation and frozen storage on 42-day-old AS-1 RBCs.

  Transfusion 20010401

• Distinct modes of mature and precursor tRNA binding to Escherichia coli RNase P RNA revealed by NAIM analyses.

  RNA (New York, N.Y.) 20010401

• Inosine improves gut permeability and vascular reactivity in endotoxic shock.

  Critical care medicine 20010401

• Exogenous administration of endogenous compounds: an emerging drug-development strategy in critical care pharmacology.

  Critical care medicine 20010401

• Cytosolic high K(m) 5'-nucleotidase and 5'(3')-deoxyribonucleotidase in substrate cycles involved in nucleotide metabolism.

  The Journal of biological chemistry 20010302

• Adenosine increases ventilation rate, cardiac performance and haemolymph velocity in the American lobster Homarus americanus.

  The Journal of experimental biology 20010301

• Ontogenic and longitudinal activity of Na(+)-nucleoside transporters in the human intestine.

  American journal of physiology. Gastrointestinal and liver physiology 20010301

• Na+ reabsorption in cultured rat epididymal epithelium via the Na+/nucleoside cotransporter.

  Biology of reproduction 20010301

• Adenosine deaminase: functional implications and different classes of inhibitors.

  Medicinal research reviews 20010301

• Metabolic fate of AMP, IMP, GMP and XMP in the cytosol of rat brain: an experimental and theoretical analysis.

  Journal of neurochemistry 20010301

• Antiadrenergic effects of adenosine in pressure overload hypertrophy.

  Hypertension (Dallas, Tex. : 1979) 20010301

• Investigation of various genotype characteristics for inosine accumulation in Escherichia coli W3110.

  Bioscience, biotechnology, and biochemistry 20010301

• Treatment of 104 cases of chemotherapy-induced leukopenia by injection of drugs into Zusanli.

  Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 20010301

• Comparison of the potency of adenosine as an agonist at human adenosine receptors expressed in Chinese hamster ovary cells.

  Biochemical pharmacology 20010215

• In situ kinetic characterization of methylthioadenosine transport by the adenosine transporter (P2) of the African Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense.

  Biochemical pharmacology 20010215

• A novel proton-dependent nucleoside transporter, CeCNT3, from Caenorhabditis elegans.

  Molecular pharmacology 20010201

• Renal interstitial adenosine metabolism during ischemia in dogs.

  American journal of physiology. Renal physiology 20010201

• [Pharmacological profiles of mycophenolate mofetil (CellCept), a new immunosuppressive agent].

  Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20010201

• A new ceramide from the basidiomycete Russula cyanoxantha.

  Lipids 20010201

• Blood purine and energy status in rats with colitis.

  Digestive diseases and sciences 20010201

• Energy-related metabolites during and after induced myocardial infarction with special emphasis on the reperfusion injury after extracorporeal circulation.

  Acta physiologica Scandinavica 20010201

• Transition state structure of purine nucleoside phosphorylase and principles of atomic motion in enzymatic catalysis.

  Biochemistry 20010130

• Nucleoside transport inhibition in ischemic myocardium results in enhanced taurine efflux.

  European journal of pharmacology 20010105

• The main products of the low molecular mass fraction in the venom of the spider Latrodectus menavodi.

  Toxicon : official journal of the International Society on Toxinology 20010101

• A3 adenosine receptor activation triggers phosphorylation of protein kinase B and protects rat basophilic leukemia 2H3 mast cells from apoptosis.

  Molecular pharmacology 20010101

• Metabolic fate of extracellular NAD in human skin fibroblasts.

  Journal of cellular biochemistry 20010101

• Purines inhibit poly(ADP-ribose) polymerase activation and modulate oxidant-induced cell death.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010101

• Molecular dynamics of DNA quadruplex molecules containing inosine, 6-thioguanine and 6-thiopurine.

  Biophysical journal 20010101

• Structure-activity relationships for a collection of structurally diverse inhibitors of purine nucleoside phosphorylase.

  Chemical & pharmaceutical bulletin 20010101

• Adenosine and hemodialysis in humans.

  Journal of investigative medicine : the official publication of the American Federation for Clinical Research 20010101

• Adenosine and neurotrauma: therapeutic perspectives.

  Neurological research 20010101

• Functional production of mammalian concentrative nucleoside transporters in Saccharomyces cerevisiae.

  Molecular membrane biology 20010101

• Use of DNA molecules substituted with unnatural nucleotides to probe specific drug-DNA interactions.

  Methods in enzymology 20010101

• Acyclic/carbocyclic guanosine analogues as anti-herpesvirus agents.

  Nucleosides, nucleotides & nucleic acids 20010101

• Intracellular Ca(2+)-mobilizing adenine nucleotides. Synthesis and biological activity of cyclic ADP-carbocyclic-ribose and C-glycosidic analog of adenophostin A.

  Nucleosides, nucleotides & nucleic acids 20010101

• Wobble base-pairing in codon-anticodon interactions: a theoretical modelling study.

  Indian journal of biochemistry & biophysics 20010101

• Interaction between ATP and nerve growth factor signalling in the survival and neuritic outgrowth from PC12 cells.

  Neuroscience 20010101

• Point mutations induced by 1,2-epoxy-3-butene N1 deoxyinosine adducts.

  Environmental and molecular mutagenesis 20010101

• Ischemic and reperfusive release of the endogenous purines and its influence on the myocardial viability during beta-adrenergic blockade.

  Polish journal of pharmacology 20010101

• Coronary metabolic adaptation restricted by endothelin in the dog heart.

  Acta physiologica Hungarica 20010101

• Ab initio conformational analysis of nucleic acid components: intrinsic energetic contributions to nucleic acid structure and dynamics.

  Biopolymers 20010101

• A purine-sensitive mechanism regulates the molecular program for axon growth.

  Restorative neurology and neuroscience 20010101

• Synthetic study of guanofosfocin. Synthesis of 8-(mannopyranosyloxy)inosine derivative.

  Nucleic acids research. Supplement (2001) 20010101

• Synthesis, Characterization and Antiviral Properties of Pd(II) Complexes With Penciclovir.

  Metal-based drugs 20010101

• Molecular cloning and functional characterization of inhibitor-sensitive (mENT1) and inhibitor-resistant (mENT2) equilibrative nucleoside transporters from mouse brain.

  The Biochemical journal 20001201

• Inosine and 2'-deoxyinosine and their synthetic analogues: lipophilicity in the relation to their retention in reversed-phase liquid chromatography and the stability characteristics.

  Journal of pharmaceutical and biomedical analysis 20001201

• Virtual combinatorial syntheses and computational screening of new potential anti-herpes compounds.

  Journal of medicinal chemistry 19990826

• Molecular cloning and functional characterization of nitrobenzylthioinosine (NBMPR)-sensitive (es) and NBMPR-insensitive (ei) equilibrative nucleoside transporter proteins (rENT1 and rENT2) from rat tissues.

  The Journal of biological chemistry 19971107

• Unique intracellular activation of the potent anti-human immunodeficiency virus agent 1592U89.

  Antimicrobial agents and chemotherapy 19970501

• Inhibition of Pneumocystis carinii dihydropteroate synthetase by para-acetamidobenzoic acid: possible mechanism of action of isoprinosine in human immunodeficiency virus infection.

  Antimicrobial agents and chemotherapy 19930601

• The influence of inosine on adriamycin-induced cardiomyopathy in rats.

  European journal of cancer & clinical oncology 19861101

• Inhibition of herpes simplex virus DNA polymerase by purine ribonucleoside monophosphates.

  The Journal of biological chemistry 19860205