580-15-4 | 6-Aminoquinoline

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$8.00	$5.00
5g	98%	in stock	$18.00	$12.00
10g	98%	in stock	$20.00	$14.00
25g	98%	in stock	$36.00	$25.00

Description

• Catalog Number: AB50939
• Chemical Name: 6-Aminoquinoline
• CAS Number: 580-15-4
• Molecular Formula: C9H8N2
• Molecular Weight: 144.1732
• MDL Number: MFCD00006803
• SMILES: Nc1ccc2c(c1)cccn2
• NSC Number: 58388

Computed Properties

• Complexity: 136
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 1
• XLogP3: 1.3

Literature

• Aminoquinolines as fluorescent labels for hydrophilic interaction liquid chromatography of oligosaccharides.

  Biological chemistry 20120801

• Hypoxia-selective, enzymatic conversion of 6-nitroquinoline into a fluorescent helicene: pyrido[3,2-f]quinolino[6,5-c]cinnoline 3-oxide.

  The Journal of organic chemistry 20120406

• A fluorogenic, small molecule reporter for mammalian phospholipase C isozymes.

  ACS chemical biology 20110318

• Synthesis and pharmacological evaluation of some quinoline derivatives as potential cognition enhancers.

  Arzneimittel-Forschung 20110101

• Fragment-based screening by X-ray crystallography, MS and isothermal titration calorimetry to identify PNMT (phenylethanolamine N-methyltransferase) inhibitors.

  The Biochemical journal 20101001

• Glycan labeling strategies and their use in identification and quantification.

  Analytical and bioanalytical chemistry 20100801

• From 6-aminoquinolone antibacterials to 6-amino-7-thiopyranopyridinylquinolone ethyl esters as inhibitors of Staphylococcus aureus multidrug efflux pumps.

  Journal of medicinal chemistry 20100610

• The 6-aminoquinolone WC5 inhibits human cytomegalovirus replication at an early stage by interfering with the transactivating activity of viral immediate-early 2 protein.

  Antimicrobial agents and chemotherapy 20100501

• Application of the dipeptidyl peptidase IV (DPPIV/CD26) based prodrug approach to different amine-containing drugs.

  Journal of medicinal chemistry 20100128

• Interference of alpha-alkyl-substituted pirinixic acid derivatives with neutrophil functions and signalling pathways.

  European journal of pharmacology 20091001

• An overview of conventional and emerging analytical methods for the determination of mycotoxins.

  International journal of molecular sciences 20090101

• Aminoglycosides: molecular insights on the recognition of RNA and aminoglycoside mimics.

  Perspectives in medicinal chemistry 20090101

• Novel and potent inhibitors of 5-lipoxygenase product synthesis based on the structure of pirinixic acid.

  Journal of medicinal chemistry 20080911

• Ultraviolet photodissociation at 355 nm of fluorescently labeled oligosaccharides.

  Analytical chemistry 20080701

• Molecular probe for enzymatic activity with dual output.

  Bioorganic & medicinal chemistry 20071201

• Synthesis and biological evaluation of indoloquinolines and pyridocarbazoles: a new example of unexpected photoreduction accompanying photocyclization.

  Chemical & pharmaceutical bulletin 20070901

• Optimization of separation and detection of 6-aminoquinolyl derivatives of amino acids by using reversed-phase liquid chromatography with on line UV, fluorescence and electrochemical detection.

  Analytica chimica acta 20070612

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Prediction of genotoxicity of chemical compounds by statistical learning methods.

  Chemical research in toxicology 20050601

• Wavelength-ratiometric near-physiological pH sensors based on 6-aminoquinolinium boronic acid probes.

  Talanta 20050430

• 6-Aminoquinolones: photostability, cellular distribution and phototoxicity.

  Toxicology in vitro : an international journal published in association with BIBRA 20041001

• A photochemical approach to pyridopyrroloquinoline derivatives as new potential anticancer agents.

  Chemical & pharmaceutical bulletin 20040601

• A novel structural class of potent inhibitors of NF-kappa B activation: structure-activity relationships and biological effects of 6-aminoquinazoline derivatives.

  Bioorganic & medicinal chemistry 20030901

• Determination of cellular carbohydrates in peanut fungal pathogens and baker's yeast by capillary electrophoresis and electrochromatography.

  Journal of agricultural and food chemistry 20011101