580-18-7 | 3-Hydroxyquinoline

Packsize	Purity	Availability	Price	Discounted Price
250mg	97%	in stock	$6.00	$4.00
1g	97%	in stock	$7.00	$5.00
5g	97%	in stock	$20.00	$14.00
10g	97%	in stock	$39.00	$28.00
25g	97%	in stock	$79.00	$55.00
100g	97%	in stock	$312.00	$219.00

Description

• Catalog Number: AB44602
• Chemical Name: 3-Hydroxyquinoline
• CAS Number: 580-18-7
• Molecular Formula: C9H7NO
• Molecular Weight: 145.1580
• MDL Number: MFCD00169018
• SMILES: Oc1cnc2c(c1)cccc2

Computed Properties

• Complexity: 138
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 1
• XLogP3: 2.1

Upstream Synthesis Route

3-Hydroxyquinoline, also known as 3-Hydroxy-1-azanaphthalene, is an important compound in chemical synthesis with versatile applications. One of the primary uses of 3-Hydroxyquinoline is as a chelating ligand in coordination chemistry. It forms stable complexes with various metal ions, making it valuable in metal ion sensing and separation processes.In organic synthesis, 3-Hydroxyquinoline serves as a key building block for the preparation of a wide range of bioactive molecules and pharmaceuticals. Its unique structure allows for the introduction of functional groups at different positions, enabling the synthesis of diverse chemical compounds with specific properties.Additionally, 3-Hydroxyquinoline exhibits fluorescent properties, making it a useful fluorescent probe in analytical chemistry and biological studies. Its fluorescent behavior can be exploited for the detection and quantification of metal ions, as well as for monitoring enzyme activities and cellular processes in biological systems.Overall, 3-Hydroxyquinoline plays a crucial role in chemical synthesis, coordination chemistry, and analytical applications, making it a valuable compound in various fields of chemistry and pharmaceutical research.

Literature

• Sensitisation of the near-infrared emission of Nd(III) from the singlet state of porphyrins bearing four 8-hydroxyquinolinylamide chelates.

  Chemphyschem : a European journal of chemical physics and physical chemistry 20120917

• ESIPT-mediated photocycloadditions of 3-hydroxyquinolinones: development of a fluorescence quenching assay for reaction screening.

  Organic letters 20110318

• An analysis of the regioselectivity of aromatic hydroxylation and N-oxygenation by cytochrome P450 enzymes.

  Drug metabolism and disposition: the biological fate of chemicals 20040301

• Study of in vitro glucuronidation of hydroxyquinolines with bovine liver microsomes.

  Fundamental & clinical pharmacology 20021201

• Total syntheses of thiocoraline and BE-22179 and assessment of their DNA binding and biological properties.

  Journal of the American Chemical Society 20010131