59-05-2 | Methotrexate

Packsize	Purity	Availability	Price	Discounted Price
1mg	95%	in stock	$8.00	$5.00
1g	95%	in stock	$315.00	$221.00
5g	95%	in stock	$1,200.00	$840.00

Description

• Catalog Number: AB52366
• Chemical Name: Methotrexate
• CAS Number: 59-05-2
• Molecular Formula: C20H22N8O5
• Molecular Weight: 454.4393
• MDL Number: MFCD00150847
• SMILES: OC(=O)CC[C@@H](C(=O)O)NC(=O)c1ccc(cc1)N(Cc1cnc2c(n1)c(N)nc(n2)N)C
• NSC Number: 740

Computed Properties

• Complexity: 704
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 33
• Hydrogen Bond Acceptor Count: 12
• Hydrogen Bond Donor Count: 5
• Rotatable Bond Count: 9
• XLogP3: -1.8

Upstream Synthesis Route

The application of (S)-2-(4-(((2,4-Diaminopteridin-6-yl)methyl)(methyl)amino)benzamido)pentanedioic acid in chemical synthesis plays a crucial role in the field of medicinal chemistry and pharmaceuticals. This compound serves as a key building block for the synthesis of folate-based drugs and antifolate agents. By incorporating this acid into the molecular structure of compounds, chemists can enhance their biological activity and target specific enzymes involved in diseases such as cancer and microbial infections. Additionally, the presence of the pteridine moiety in the acid provides opportunities for further diversification and modification, allowing for the development of novel drug candidates with improved pharmacological properties.

Literature

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• Low-dose prednisone inclusion in a methotrexate-based, tight control strategy for early rheumatoid arthritis.

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  International journal of pharmaceutics 20120820

• St. John's wort significantly increased the systemic exposure and toxicity of methotrexate in rats.

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  The New England journal of medicine 20120809

• Chemotherapy-related magnetic resonance imaging abnormalities mimicking disease progression following intraventricular liposomal cytarabine and high dose methotrexate for neurolymphomatosis.

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• Growth in children receiving contemporary disease specific therapy for Crohn's disease.

  Archives of disease in childhood 20120801

• A U-HPLC-ESI-MS/MS-based stable isotope dilution method for the detection and quantitation of methotrexate in plasma.

  Therapeutic drug monitoring 20120801

• Differential gene expression profiles may differentiate responder and nonresponder patients with rheumatoid arthritis for methotrexate (MTX) monotherapy and MTX plus tumor necrosis factor inhibitor combined therapy.

  The Journal of rheumatology 20120801

• Vasculitis associated with tumor necrosis factor-α inhibitors.

  Mayo Clinic proceedings 20120801

• Adjuvant treatments for triple-negative breast cancers.

  Annals of oncology : official journal of the European Society for Medical Oncology 20120801

• Mechanism inspired development of rationally designed dihydrofolate reductase inhibitors as anticancer agents.

  Journal of medicinal chemistry 20120726

• Fabrication of electrolytic cell for online post-column electrochemical derivatization in ion chromatography.

  Analytica chimica acta 20120720

• Novel tricyclic indeno[2,1-d]pyrimidines with dual antiangiogenic and cytotoxic activities as potent antitumor agents.

  Bioorganic & medicinal chemistry 20120715

• Effects of Viscum album L. extract and quercetin on methotrexate-induced cyto-genotoxicity in mouse bone-marrow cells.

  Mutation research 20120704

• Effect of intravitreal methotrexate and aqueous humor cytokine levels in refractory retinal vasculitis in Behcet disease.

  Retina (Philadelphia, Pa.) 20120701

• Discovery of common urinary biomarkers for hepatotoxicity induced by carbon tetrachloride, acetaminophen and methotrexate by mass spectrometry-based metabolomics.

  Journal of applied toxicology : JAT 20120701

• Posterior reversible encephalopathy syndrome and oral methotrexate.

  Clinical neurology and neurosurgery 20120701

• Dermal distribution of hyaluronan in psoriatic arthritis; coexistence of CD44, MMP3 and MMP9.

  Acta dermato-venereologica 20120701

• Methotrexate polyglutamates as a marker of patient compliance and clinical response in psoriasis: a single-centre prospective study.

  The British journal of dermatology 20120701

• A phase II, double-blind, randomised, placebo-controlled study of BMS945429 (ALD518) in patients with rheumatoid arthritis with an inadequate response to methotrexate.

  Annals of the rheumatic diseases 20120701

• How to treat refractory arthritis in lupus?

  Joint, bone, spine : revue du rhumatisme 20120701

• Target identification by chromatographic co-elution: monitoring of drug-protein interactions without immobilization or chemical derivatization.

  Molecular & cellular proteomics : MCP 20120701

• Inhibition of nuclear factor-κB by dehydroxymethylepoxyquinomicin induces schedule-dependent chemosensitivity to anticancer drugs and enhances chemoinduced apoptosis in osteosarcoma cells.

  Anti-cancer drugs 20120701

• Effects of glycyrrhizin on biliary transport and hepatic levels of glutathione in rats.

  Biopharmaceutics & drug disposition 20120701

• Role of routine monitoring of liver and renal function during treatment of ectopic pregnancies with single-dose methotrexate protocol.

  Fertility and sterility 20120701

• Blockade of interleukin-6 receptor suppresses the proliferation of H460 lung cancer stem cells.

  International journal of oncology 20120701

• The preformulation stability studies of a proline prodrug of methotrexate.

  Medicinal chemistry (Shariqah (United Arab Emirates)) 20120701

• Intracellular disposition of methotrexate in acute lymphoblastic leukemia in children.

  Current drug metabolism 20120701

• Mycophenolate mofetil: fully utilizing its benefits for GvHD prophylaxis.

  International journal of hematology 20120701

• Effect of chemotherapy in patients with resected small-cell or large-cell neuroendocrine carcinoma.

  Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20120701

• Methotrexate chemotherapy promotes osteoclast formation in the long bone of rats via increased pro-inflammatory cytokines and enhanced NF-κB activation.

  The American journal of pathology 20120701

• Biologic monotherapy as initial treatment in patients with early rheumatoid arthritis.

  Rheumatology (Oxford, England) 20120701

• Not all that itches is urticaria.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20120701

• Protein interface remodeling in a chemically induced protein dimer.

  Journal of molecular recognition : JMR 20120701

• Successful treatment of refractory Takayasu arteritis with tacrolimus.

  The Journal of rheumatology 20120701

• My treatment approach to rheumatoid arthritis.

  Mayo Clinic proceedings 20120701

• A thymidylate synthase ternary complex-specific antibody, FTS, permits functional monitoring of fluoropyrimidines dosing.

  Oncotarget 20120701

• Comparative study on methotrexate and hydroxychloroquine in the treatment of rheumatoid arthritis.

  Mymensingh medical journal : MMJ 20120701

• Genetic variants of thiopurine and folate metabolic pathways determine 6-MP-mediated hematological toxicity in childhood ALL.

  Pharmacogenomics 20120701

• Current treatments of rheumatoid arthritis: from the 'NinJa' registry.

  Expert review of clinical immunology 20120701

• Diagnostic and therapeutic challenges. Bilateral occlusive retinal vasculitis.

  Retina (Philadelphia, Pa.) 20120701

• [Association between the methylenetetrahydrofolate reductase gene polymorphisms and haplotype with toxicity response of high dose methotrexate chemotherapy].

  Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi 20120701

• Association between radiotherapy vs no radiotherapy based on early response to VAMP chemotherapy and survival among children with favorable-risk Hodgkin lymphoma.

  JAMA 20120627

• [Neurotoxicity due to methotrexate in paediatric patients. Description of the clinical symptoms and neuroimaging findings].

  Revista de neurologia 20120616

• Hemocompatibility of liposomes loaded with lipophilic prodrugs of methotrexate and melphalan in the lipid bilayer.

  Journal of controlled release : official journal of the Controlled Release Society 20120610

• Melanoma coordinates general and cell-specific mechanisms to promote methotrexate resistance.

  Experimental cell research 20120610

• Neoadjuvant chemotherapy with methotrexate, cisplatin, and doxorubicin with or without ifosfamide in nonmetastatic osteosarcoma of the extremity: an Italian sarcoma group trial ISG/OS-1.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120610

• Ifosfamide in the neoadjuvant treatment of osteogenic sarcoma.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120610

• Psoriatic arthritis: treatment strategies using anti-inflammatory drugs and classical DMARDs.

  Reumatismo 20120605

• Magnetic resonance imaging is appropriate for determining the osteotomy plane for appendicular osteosarcoma after neoadjuvant chemotherapy.

  Medical oncology (Northwood, London, England) 20120601

• Classical CMF regimen as adjuvant chemotherapy for triple-negative breast cancer may be more effective compared with anthracycline or taxane-based regimens.

  Medical oncology (Northwood, London, England) 20120601

• Methylenetetrahydrofolate reductase polymorphisms, C677T and A1298C, are associated with methotrexate-related toxicities in Korean patients with rheumatoid arthritis.

  Rheumatology international 20120601

• Reactivation of hepatitis B virus in a hepatitis B surface antigen-negative patient with rheumatoid arthritis treated with methotrexate.

  Modern rheumatology 20120601

• Prognostic significance of UBE2C mRNA expression in high-risk early breast cancer. A Hellenic Cooperative Oncology Group (HeCOG) Study.

  Annals of oncology : official journal of the European Society for Medical Oncology 20120601

• Influence of folate pathway polymorphisms on high-dose methotrexate-related toxicity and survival in childhood acute lymphoblastic leukemia.

  Leukemia & lymphoma 20120601

• Reduced time for urinary alkalinization before high-dose methotrexate with preadmission oral bicarbonate.

  Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners 20120601

• Brief report: a phase IIa, randomized, double-blind, placebo-controlled trial of apilimod mesylate, an interleukin-12/interleukin-23 inhibitor, in patients with rheumatoid arthritis.

  Arthritis and rheumatism 20120601

• Methotrexate increases expression of cell cycle checkpoint genes via JNK activation.

  Arthritis and rheumatism 20120601

• Trial of early aggressive therapy in polyarticular juvenile idiopathic arthritis.

  Arthritis and rheumatism 20120601

• Cryptosporidium gastroenteritis in Egyptian children with acute lymphoblastic leukemia: magnitude of the problem.

  Infection 20120601

• A tight control treatment strategy aiming for remission in early rheumatoid arthritis is more effective than usual care treatment in daily clinical practice: a study of two cohorts in the Dutch Rheumatoid Arthritis Monitoring registry.

  Annals of the rheumatic diseases 20120601

• The Toll-like receptor 4 agonist MRP8/14 protein complex is a sensitive indicator for disease activity and predicts relapses in systemic-onset juvenile idiopathic arthritis.

  Annals of the rheumatic diseases 20120601

• Differential drug retention between anti-TNF agents and alternative biological agents after inadequate response to an anti-TNF agent in rheumatoid arthritis patients.

  Annals of the rheumatic diseases 20120601

• Loss of E-cadherin promotes the growth, invasion and drug resistance of colorectal cancer cells and is associated with liver metastasis.

  Molecular biology reports 20120601

• Methothrexate attenuates early neutrophil infiltration and the associated lipid peroxidation in the injured spinal cord but does not induce neurotoxicity in the uninjured spinal cord in rats.

  Acta neurochirurgica 20120601

• The roles of surgery and EMA/CO chemotherapy regimen in primary refractory and non-refractory gestational trophoblastic neoplasia.

  Journal of cancer research and clinical oncology 20120601

• Relapse rates after two versus three consolidation courses of methotrexate in the treatment of low-risk gestational trophoblastic neoplasia.

  Gynecologic oncology 20120601

• Azathioprine as monotherapy for scleritis in relapsing polychondritis.

  Ocular immunology and inflammation 20120601

• Treatment of nonmetastatic and metastatic low-risk gestational trophoblastic neoplasia: factors associated with resistance to single-agent methotrexate chemotherapy.

  Gynecologic oncology 20120601

• The effects of chemotherapy on cognitive function in a mouse model: a prospective study.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20120601

• GnRH-III based multifunctional drug delivery systems containing daunorubicin and methotrexate.

  European journal of medicinal chemistry 20120601

• Effects of double filtration plasmapheresis, leflunomide, and methotrexate on inflammatory changes found through magnetic resonance imaging in early rheumatoid arthritis.

  The Journal of rheumatology 20120601

• Medical management of ectopic pregnancy.

  Clinical obstetrics and gynecology 20120601

• Methotrexate: the pharmacology behind medical treatment for ectopic pregnancy.

  Clinical obstetrics and gynecology 20120601

• Optimal use of non-biologic therapy in the treatment of rheumatoid arthritis.

  Rheumatology (Oxford, England) 20120601

• Infliximab exerts no direct hepatotoxic effect on HepG2 cells in vitro.

  Digestive diseases and sciences 20120601

• Safety and efficacy of etanercept in a cohort of patients with juvenile idiopathic arthritis under 4 years of age.

  The Journal of rheumatology 20120601

• Langerhans cell histiocytosis presenting as a multi-system disorder in an infant.

  International journal of dermatology 20120601

• Improved outcome of high-risk early HER2 positive breast cancer with high CXCL13-CXCR5 messenger RNA expression.

  Clinical breast cancer 20120601

• Mantle cell lymphoma: 2012 update on diagnosis, risk-stratification, and clinical management.

  American journal of hematology 20120601

• The activity of the Bone and Soft Tissue Tumor Study Group of the Japan Clinical Oncology Group.

  Japanese journal of clinical oncology 20120601

• EP-EMA regimen (etoposide and cisplatin with etoposide, methotrexate, and dactinomycin) in a series of 18 women with gestational trophoblastic neoplasia.

  International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20120601

• Gestational trophoblastic neoplasia.

  Obstetrics and gynecology clinics of North America 20120601

• DNA synthesis as a therapeutic target: the first 65 years.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20120601

• Prediction of response of collagen-induced arthritis rats to methotrexate: an (1)H-NMR-based urine metabolomic analysis.

  Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20120601

• Lessons for the use of non-biologic anchor treatments for rheumatoid arthritis in the era of biologic therapies.

  Rheumatology (Oxford, England) 20120601

• [Methotrexate-induced cutaneous reactions: two case reports].

  Annales de dermatologie et de venereologie 20120601

• Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.

  Journal of medicinal chemistry 20120524

• Multilevel latent variable models for global health-related quality of life assessment.

  Statistics in medicine 20120520

• Physico-chemical characteristics of methotrexate-entrapped oleic acid-containing deformable liposomes for in vitro transepidermal delivery targeting psoriasis treatment.

  International journal of pharmaceutics 20120510

• Conventional combination treatment versus biological treatment in methotrexate-refractory early rheumatoid arthritis: 2 year follow-up of the randomised, non-blinded, parallel-group Swefot trial.

  Lancet (London, England) 20120505

• Peptide-mediated targeted drug delivery.

  Medicinal research reviews 20120501

• Repeated IL-10 measurement in aqueous humor and OCT imaging are valuable tools to monitor intraocular lymphoma treated with intravitreal injections of methotrexate.

  Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20120501

• Molecular modeling approach to predict a binding mode for the complex methotrexate-carboxypeptidase G2.

  Journal of molecular modeling 20120501

• Inhibition of EGFR phosphorylation in a panel of human breast cancer cells correlates with synergistic interactions between gefitinib and 5'-DFUR, the bioactive metabolite of Xeloda.

  Breast cancer research and treatment 20120501

• The effect of folinic acid on methylenetetrahydrofolate reductase polymorphisms in methotrexate-treated allogeneic hematopoietic stem cell transplants.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20120501

• CNS disease in younger patients with aggressive B-cell lymphoma: an analysis of patients treated on the Mabthera International Trial and trials of the German High-Grade Non-Hodgkin Lymphoma Study Group.

  Annals of oncology : official journal of the European Society for Medical Oncology 20120501

• Sequential Stevens-Johnson syndrome and photo-recall phenomenon.

  The British journal of dermatology 20120501

• Comparison of clinical characteristics and management of inflammatory bowel disease in Hong Kong versus Melbourne.

  Journal of gastroenterology and hepatology 20120501

• Methotrexate-mediated inhibition of RAD51 expression and homologous recombination in cancer cells.

  Journal of cancer research and clinical oncology 20120501

• Giant cell arteritis: a review of classification, pathophysiology, geoepidemiology and treatment.

  Autoimmunity reviews 20120501

• Development of a multiparametric cell-based protocol to screen and classify the hepatotoxicity potential of drugs.

  Toxicological sciences : an official journal of the Society of Toxicology 20120501

• Long-term results of combined preradiation chemotherapy and age-tailored radiotherapy doses for childhood medulloblastoma.

  Journal of neuro-oncology 20120501

• Accelerated MVAC chemotherapy in patients with advanced bladder cancer previously treated with a platinum-gemcitabine regimen.

  European journal of cancer (Oxford, England : 1990) 20120501

• ALK inhibitor crizotinib combined with intrathecal methotrexate treatment for non-small cell lung cancer with leptomeningeal carcinomatosis.

  Lung cancer (Amsterdam, Netherlands) 20120501

• Outcomes after anti-rheumatic drug use before and during pregnancy: a cohort study among 150,000 pregnant women and expectant fathers.

  Scandinavian journal of rheumatology 20120501

• Tumor necrosis factor-α inhibitor use is not associated with lipid changes in rheumatoid arthritis.

  The Journal of rheumatology 20120501

• The facile synthesis of multifunctional PAMAM dendrimer conjugates through copper-free click chemistry.

  Bioorganic & medicinal chemistry letters 20120501

• A randomized, double-blind, parallel, single-site pilot trial to compare two different starting doses of methotrexate in methotrexate-naïve adult patients with rheumatoid arthritis.

  Clinical therapeutics 20120501

• Bullous variant of acral erythema in a child after high-dose methotrexate.

  Pediatric hematology and oncology 20120501

• Immunotherapies in rheumatologic disorders.

  The Medical clinics of North America 20120501

• A rare presentation of erythrodermic mycosis fungoides.

  Cutis 20120501

• A child with pulmonary and liver Langerhans'-cell histiocytosis.

  Chinese medical journal 20120501

• [Sulphasalazine in patients with rheumatoid arthritis in China: a cross-sectional study].

  Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20120418

• Bifunctional PAMAM dendrimer conjugates of folic acid and methotrexate with defined ratio.

  Biomacromolecules 20120409

• A pharmacist-led information technology intervention for medication errors (PINCER): a multicentre, cluster randomised, controlled trial and cost-effectiveness analysis.

  Lancet (London, England) 20120407

• Vandetanib mediates anti-leukemia activity by multiple mechanisms and interacts synergistically with DNA damaging agents.

  Investigational new drugs 20120401

• What has happened to VBM (vinblastine, bleomycin, and methotrexate) chemotherapy for early-stage Hodgkin lymphoma?

  Critical reviews in oncology/hematology 20120401

• Pathological complete response rates following different neoadjuvant chemotherapy regimens for operable breast cancer according to ER status, in two parallel, randomized phase II trials with an adaptive study design (ECTO II).

  Breast cancer research and treatment 20120401

• Etanercept for the treatment of intractable hemophagocytic syndrome with systemic lupus erythematosus.

  Modern rheumatology 20120401

• Germline genetic polymorphisms may influence chemotherapy response and disease outcome in osteosarcoma: a pilot study.

  Cancer 20120401

• Primary B-cell lymphoma of the cauda equina, successfully treated with high-dose methotrexate plus high-dose cytarabine: a case report with MRI findings.

  Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20120401

• Unexpected pancytopenia following treatment of acute lymphoblastic leukemia.

  American journal of hematology 20120401

• Infliximab plus methotrexate is superior to methotrexate alone in the treatment of psoriatic arthritis in methotrexate-naive patients: the RESPOND study.

  Annals of the rheumatic diseases 20120401

• A phase IIb dose-ranging study of the oral JAK inhibitor tofacitinib (CP-690,550) versus placebo in combination with background methotrexate in patients with active rheumatoid arthritis and an inadequate response to methotrexate alone.

  Arthritis and rheumatism 20120401

• Treating to target matrix metalloproteinase 3 normalisation together with disease activity score below 2.6 yields better effects than each alone in rheumatoid arthritis patients: T-4 Study.

  Annals of the rheumatic diseases 20120401

• Interstitial granulomatous dermatitis: a distinct entity with characteristic histological and clinical pattern.

  The British journal of dermatology 20120401

• Treatment with methotrexate inhibits atherogenesis in cholesterol-fed rabbits.

  Journal of cardiovascular pharmacology 20120401

• Response to traditional disease-modifying anti-rheumatic drugs in indigent South Africans with early rheumatoid arthritis.

  Clinical rheumatology 20120401

• Dysphagia, oral telangiectasia, and Raynaud syndrome.

  Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20120401

• Effectiveness of sulfasalazine and methotrexate in 1102 DMARD-naive patients with early RA.

  Rheumatology (Oxford, England) 20120401

• Behçet's disease: successful treatment with infliximab in 7 patients with severe vascular manifestations. A retrospective analysis.

  Arthritis care & research 20120401

• Aggressive therapy in patients with early arthritis results in similar outcome compared with conventional care: the STREAM randomized trial.

  Rheumatology (Oxford, England) 20120401

• Postoperative dose-dense sequential versus concomitant administration of epirubicin and paclitaxel in patients with node-positive breast cancer: 5-year results of the Hellenic Cooperative Oncology Group HE 10/00 phase III Trial.

  Breast cancer research and treatment 20120401

• Methotrexate modulates tight junctions through NF-κB, MEK, and JNK pathways.

  Journal of pediatric gastroenterology and nutrition 20120401

• Minimally-aggressive gestational trophoblastic neoplasms.

  Gynecologic oncology 20120401

• Has there been a change in the natural history of Crohn's disease? Surgical rates and medical management in a population-based inception cohort from Western Hungary between 1977-2009.

  The American journal of gastroenterology 20120401

• Photochemical release of methotrexate from folate receptor-targeting PAMAM dendrimer nanoconjugate.

  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20120401

• Bosentan, an endothelin receptor antagonist, ameliorates collagen-induced arthritis: the role of TNF-α in the induction of endothelin system genes.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20120401

• Chemotherapy-induced toxicity is highly heritable in Drosophila melanogaster.

  Pharmacogenetics and genomics 20120401

• Red blood cell folate concentrations and polyglutamate distribution in juvenile arthritis: predictors of folate variability.

  Pharmacogenetics and genomics 20120401

• Idiopathic hypertrophic cranial pachymeningitis presenting as acute painless visual loss.

  International ophthalmology 20120401

• Recent advances in treatment of advanced urothelial carcinoma.

  Current urology reports 20120401

• Neuropsychological performance in survivors of breast cancer more than 20 years after adjuvant chemotherapy.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120401

• Improved sensitivity for methotrexate analysis using enzyme multiplied immunoassay technique on the Siemens Viva-E instrument.

  Therapeutic drug monitoring 20120401

• The effects of anti-TNF-α treatment with adalimumab on growth in children with Crohn's disease (CD).

  Journal of Crohn's & colitis 20120401

• Choriocarcinoma of the lung masquerading as a persisting pregnancy of unknown location (PUL).

  The Australian & New Zealand journal of obstetrics & gynaecology 20120401

• Limited end-user knowledge of methotrexate despite patient education: an assessment of rheumatologic preventive practice and effectiveness.

  Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20120401

• Teratogen update: methotrexate.

  Birth defects research. Part A, Clinical and molecular teratology 20120401

• Pancytopenia, mucositis, and hepatotoxicity after intralesional methotrexate injection in a patient treated with peritoneal dialysis.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20120401

• Recurrent ventricular tachycardia in a child with juvenile dermatomyositis - an unusual association.

  International journal of rheumatic diseases 20120401

• Accumulating evidence for a drug-drug interaction between methotrexate and proton pump inhibitors.

  The oncologist 20120401

• Tight control early rheumatoid arthritis clinic in Hong Kong: a pilot study.

  Hong Kong medical journal = Xianggang yi xue za zhi 20120401

• High dose methotrexate treatment in childhood ALL: pilot study on the impact of the MTHFR 677C>T and 1298A>C polymorphisms on MTX-related toxicity.

  Klinische Padiatrie 20120401

• Combination therapy with infliximab and methotrexate in recalcitrant mucocutaneous Behçet disease.

  Cutis 20120401

• Oral manifestations of psoriasis. Clinical presentation and management.

  The New York state dental journal 20120401

• Low-dose prednisone inclusion in a methotrexate-based, tight control strategy for early rheumatoid arthritis: a randomized trial.

  Annals of internal medicine 20120306

• Combination therapy including glucocorticoids: the new gold standard for early treatment in rheumatoid arthritis?

  Annals of internal medicine 20120306

• Summaries for patients. Adding low-dose prednisone to methotrexate therapy for early rheumatoid arthritis.

  Annals of internal medicine 20120306

• Glucarpidase (Voraxaze) for methotrexate toxicity.

  The Medical letter on drugs and therapeutics 20120305

• Takayasu arteritis: assessment of response to medical therapy based on clinical activity criteria and imaging techniques.

  Rheumatology international 20120301

• Causes of DMARD withdrawal following ADR within 6 months of initiation among Indian rheumatoid arthritis patients.

  Rheumatology international 20120301

• Wipe sampling procedure coupled to LC-MS/MS analysis for the simultaneous determination of 10 cytotoxic drugs on different surfaces.

  Analytical and bioanalytical chemistry 20120301

• Mercaptopurine-induced hypersensitivity febrile reaction in patient with acute promyelocytic leukemia.

  Leukemia & lymphoma 20120301

• Effectiveness of disease-modifying antirheumatic drug co-therapy with methotrexate and leflunomide in rituximab-treated rheumatoid arthritis patients: results of a 1-year follow-up study from the CERERRA collaboration.

  Annals of the rheumatic diseases 20120301

• The role of MTHFR and RFC1 polymorphisms on toxicity and outcome of adult patients with hematological malignancies treated with high-dose methotrexate followed by leucovorin rescue.

  Cancer chemotherapy and pharmacology 20120301

• Sustained inhibition of progressive joint damage with rituximab plus methotrexate in early active rheumatoid arthritis: 2-year results from the randomised controlled trial IMAGE.

  Annals of the rheumatic diseases 20120301

• Combined methotrexate-dactinomycin: an effective therapy for low-risk gestational trophoblastic neoplasia.

  Gynecologic oncology 20120301

• Eosinophilic fasciitis (Shulman disease): new insights into the therapeutic management from a series of 34 patients.

  Rheumatology (Oxford, England) 20120301

• Poly(amidoamine) dendronized hollow fiber membranes: synthesis, characterization, and preliminary applications as drug delivery devices.

  Acta biomaterialia 20120301

• Evaluation of drugs with specific organ toxicities in organ-specific cell lines.

  Toxicological sciences : an official journal of the Society of Toxicology 20120301

• Rituximab for the treatment of adult relapsed/refractory CD20 positive B-ALL patients: a pilot series.

  Leukemia research 20120301

• Bullous acral erythema: an additional consideration in the differential diagnosis of pauci-inflammatory subepidermal bullae*.

  Journal of cutaneous pathology 20120301

• Effect of high-dose methotrexate chemotherapy on intestinal Bifidobacteria, Lactobacillus and Escherichia coli in children with acute lymphoblastic leukemia.

  Experimental biology and medicine (Maywood, N.J.) 20120301

• [Misleading improvement of abdominal tuberculosis with amikacin, within 72 hours].

  Medecine et maladies infectieuses 20120301

• The Cameroon 2008 Burkitt lymphoma protocol: improved event-free survival with treatment adapted to disease stage and the response to induction therapy.

  Pediatric hematology and oncology 20120301

• Clinical features and outcomes of ANCA-associated renal vasculitis.

  Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20120301

• Low prevalence of high-dose methotrexate nephropathy in patients with malignancy.

  Iranian journal of kidney diseases 20120301

• A case of B-cell lymphoma, unclassifiable, with features intermediate between diffuse large B-cell lymphoma and Burkitt lymphoma in a Korean child.

  Annals of laboratory medicine 20120301

• Urogenital manifestations in Wegener granulomatosis: a study of 11 cases and review of the literature.

  Medicine 20120301

• Adrenergic urticaria and rheumatoid arthritis in a patient with melanoma: an intricate medical management.

  Journal of drugs in dermatology : JDD 20120301

• Small cell osteosarcoma successfully treated by high-dose ifosfamide and methotrexate, combined with carboplatin and pirarubicin.

  Anticancer research 20120301

• Methotrexate therapy, rheumatoid arthritis, and life-threatening liver complications: should we be monitoring more closely?

  Scandinavian journal of rheumatology 20120301

• Diffuse large cell non-Hodgkin lymphoma with pituitary and bilateral adrenal involvement.

  Internal medicine journal 20120301

• [Bilateral tuberculous mastitis nulliparous patient, initially treated as idiopathic granulomatous mastitis].

  Ginecologia y obstetricia de Mexico 20120301

• Synthesis and biological activity of 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl regioisomers as inhibitors of de novo purine biosynthesis with selectivity for cellular uptake by high affinity folate receptors and the proton-coupled folate transporter over the reduced folate carrier.

  Journal of medicinal chemistry 20120223

• Immunochemotherapy with intensive consolidation for primary CNS lymphoma: a pilot study and prognostic assessment by diffusion-weighted MRI.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20120215

• Programmable self-assembly of antibody-oligonucleotide conjugates as small molecule and protein carriers.

  Journal of the American Chemical Society 20120215

• Long-term survival of a patient with leptomeningeal involvement by nasopharyngeal carcinoma after treatment with high-dose intravenous methotrexate.

  Head & neck 20120201

• Adding a combination of hydroxycitrate and lipoic acid (METABLOC™) to chemotherapy improves effectiveness against tumor development: experimental results and case report.

  Investigational new drugs 20120201

• Exclusive alternating chemotherapy and radiotherapy in nonmetastatic inflammatory breast cancer: 20 years of follow-up.

  International journal of radiation oncology, biology, physics 20120201

• Changes in pulmonary function up to 10 years after locoregional breast irradiation.

  International journal of radiation oncology, biology, physics 20120201

• Efficacy of folinic acid in preventing oral mucositis in allogeneic hematopoietic stem cell transplant patients receiving MTX as prophylaxis for GVHD.

  Bone marrow transplantation 20120201

• Secondary syphilis following tumor necrosis factor-α inhibitor treatment for rheumatoid arthritis.

  The Journal of dermatology 20120201

• Etanercept in combination with conventional disease-modifying antirheumatic drugs (DMARDs) in the treatment of rheumatoid arthritis patients intolerant to methotrexate.

  Modern rheumatology 20120201

• Effect of early posttransplantation tacrolimus concentration on the development of acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation from unrelated donors.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20120201

• CMF revisited in the 21st century.

  Annals of oncology : official journal of the European Society for Medical Oncology 20120201

• Single-center, retrospective analysis of efficacy and safety of tacrolimus as a second-line DMARD in combination therapy and the risk factors contributing to adverse events in 115 patients with rheumatoid arthritis.

  Clinical rheumatology 20120201

• Dosing algorithm to target a predefined AUC in patients with primary central nervous system lymphoma receiving high dose methotrexate.

  British journal of clinical pharmacology 20120201

• Use of interim [18F]fluorodeoxyglucose-positron emission tomography is not justified in diffuse large B-cell lymphoma during first-line immunochemotherapy.

  Leukemia & lymphoma 20120201

• Liver stiffness correlates with methotrexate cumulative dose in patients with rheumatoid arthritis.

  Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20120201

• Safety of immunomodulatory therapy in patients with bronchiectasis associated with rheumatic disease and IBD: a retrospective and cohort analysis.

  Clinical rheumatology 20120201

• Case of insulin edema occurring during intensive insulin therapy after bone marrow transplantation.

  The Journal of dermatology 20120201

• Functional expression and characterization in Xenopus laevis oocytes of the ABCG2 transporter derived from A549 human lung adenocarcinoma cells.

  Oncology reports 20120201

• Predicting low disease activity and remission using early treatment response to antitumour necrosis factor therapy in patients with rheumatoid arthritis: exploratory analyses from the TEMPO trial.

  Annals of the rheumatic diseases 20120201

• The C677T polymorphism in the MTHFR gene is associated with the toxicity of methotrexate in a Spanish rheumatoid arthritis population.

  Scandinavian journal of rheumatology 20120201

• The use of methotrexate for treatment of inflammatory bowel disease in clinical practice.

  Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20120201

• Herpes simplex virus-induced plasmacytic atypia.

  Journal of cutaneous pathology 20120201

• Alleviation of rheumatoid arthritis by cell-transducible methotrexate upon transcutaneous delivery.

  Biomaterials 20120201

• Overexpression of P-glycoprotein induces acquired resistance to imatinib in chronic myelogenous leukemia cells.

  Chinese journal of cancer 20120201

• Towards personalized treatment: predictors of short-term HAQ response in recent-onset active rheumatoid arthritis are different from predictors of rapid radiological progression.

  Scandinavian journal of rheumatology 20120201

• Methylene tetrahydrofolate reductase gene polymorphisms and their association with methotrexate toxicity: a meta-analysis.

  Pharmacogenetics and genomics 20120201

• Rituximab plus HyperCVAD alternating with high dose cytarabine and methotrexate for the initial treatment of patients with mantle cell lymphoma, a multicentre trial from Gruppo Italiano Studio Linfomi.

  British journal of haematology 20120201

• TIMP-1 in combination with HER2 and TOP2A for prediction of benefit from adjuvant anthracyclines in high-risk breast cancer patients.

  Breast cancer research and treatment 20120201

• Prevalence and risk factors for liver biochemical abnormalities in Canadian patients with systemic lupus erythematosus.

  The Journal of rheumatology 20120201

• Relative efficacy of perioperative gemcitabine and cisplatin versus methotrexate, vinblastine, adriamycin, and cisplatin in the management of locally advanced urothelial carcinoma of the bladder.

  Urology 20120201

• A photochemical approach for controlled drug release in targeted drug delivery.

  Bioorganic & medicinal chemistry 20120201

• Methotrexate and corticosteroids in the treatment of localized scleroderma: a standardized prospective longitudinal single-center study.

  The Journal of rheumatology 20120201

• Methotrexate: a detailed review on drug delivery and clinical aspects.

  Expert opinion on drug delivery 20120201

• Stability of extemporaneously prepared cytarabine, methotrexate sodium, and methylprednisolone sodium succinate.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20120201

• Comparison of concurrent chemoradiotherapy versus induction chemotherapy followed by radiation in patients with nasopharyngeal carcinoma.

  Anticancer research 20120201

• [ Bone and cartilage destruction in RA and its intervention. Disease-modifying antirheumatic drugs].

  Clinical calcium 20120201

• The use of methotrexate in dermatology: a review.

  The Australasian journal of dermatology 20120201

• Adverse effects of low dose methotrexate in rheumatoid arthritis patients.

  Journal of the College of Physicians and Surgeons--Pakistan : JCPSP 20120201

• Resolution of recalcitrant uveitic optic disc edema following administration of methotrexate: two case reports.

  Korean journal of ophthalmology : KJO 20120201

• Efficacy and safety of methotrexate in articular and cutaneous manifestations of systemic lupus erythematosus.

  International journal of rheumatic diseases 20120201

• [Primary systemic vasculitides].

  Deutsche medizinische Wochenschrift (1946) 20120201

• [Off-label therapy of rheumatoid arthritis and spondyloarthritis].

  Zeitschrift fur Rheumatologie 20120201

• [Guidelines for the management of Crohn's disease].

  The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi 20120201

• Dermatomyositis with extensive calcification in an adult.

  The western journal of emergency medicine 20120201

• Role of neutrophils in acrylonitrile-induced gastric mucosal damage.

  Toxicology letters 20120125

• Role of base-excision repair in the treatment of childhood acute lymphoblastic leukaemia with 6-mercaptopurine and high doses of methotrexate.

  Mutation research 20120124

• Study on formulation variables of methotrexate loaded mesoporous MCM-41 nanoparticles for dissolution enhancement.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20120123

• Liquid chromatography-tandem mass spectrometry quantification of 6-thioguanine in DNA using endogenous guanine as internal standard.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120115

• Randomized phase II/III trial assessing gemcitabine/carboplatin and methotrexate/carboplatin/vinblastine in patients with advanced urothelial cancer who are unfit for cisplatin-based chemotherapy: EORTC study 30986.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120110

• Trypanosoma brucei AP endonuclease 1 has a major role in the repair of abasic sites and protection against DNA-damaging agents.

  DNA repair 20120102

• Etoposide, mitomycin, and methotrexate combination in heavily treated breast cancer: a retrospective study.

  Breast cancer (Tokyo, Japan) 20120101

• Leflunomide use in a cytomegalovirus infection of a patient with dermatomyositis.

  Rheumatology international 20120101

• The utility of performing the initial lumbar puncture on day 8 in remission induction therapy for childhood acute lymphoblastic leukemia: TCCSG L99-15 study.

  Pediatric blood & cancer 20120101

• Higher CD3(+) and CD34(+) cell doses in the graft increase the incidence of acute GVHD in children receiving BMT for thalassemia.

  Bone marrow transplantation 20120101

• Plasma methotrexate, red blood cell methotrexate, and red blood cell folate values and outcome in children with precursor B-acute lymphoblastic leukemia: a report from the Children's Oncology Group.

  Journal of pediatric hematology/oncology 20120101

• Simple and sensitive HPLC method for the fluorometric determination of methotrexate and its major metabolites in human plasma by post-column photochemical reaction.

  Biomedical chromatography : BMC 20120101

• Chemotherapy in patients with desmoid tumors: a study from the French Sarcoma Group (FSG).

  Annals of oncology : official journal of the European Society for Medical Oncology 20120101

• Remission in early rheumatoid arthritis treated with conventional DMARDs. Results of a two-year follow-up study of El Ayachi Moroccan cohort.

  Joint, bone, spine : revue du rhumatisme 20120101

• Devastating bilateral optic nerve leukaemic infiltration.

  Clinical & experimental ophthalmology 20120101

• High dose methotrexate chemotherapy: pharmacokinetics, folate and toxicity in osteosarcoma patients.

  British journal of clinical pharmacology 20120101

• Prophylactic intrathecal chemotherapy in primary CNS lymphoma.

  Journal of neuro-oncology 20120101

• [Amyloid goiter secondary to rheumatoid arthritis. a case report].

  Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion 20120101

• Pneumocystis jiroveci pneumonia prophylaxis during maintenance therapy influences methotrexate/6-mercaptopurine dosing but not event-free survival for childhood acute lymphoblastic leukemia.

  European journal of haematology 20120101

• Inherited prothrombotic risk factors in Turkish children with acute lymphoblastic leukemia: significance of concomitant genetic mutation.

  Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20120101

• Efficacy of leflunomide addition in relation to prognostic factors for patients with active early rheumatoid arthritis failing to methotrexate in daily practice.

  Clinical rheumatology 20120101

• Beneficial effects of chlorogenic acid on methotrexate-induced cerebellar Purkinje cell damage in rats.

  Journal of chemical neuroanatomy 20120101

• [Gynecomastia in methotrexate treatment in Churg-Strauss syndrome].

  RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin 20120101

• Rheumatoid meningitis occurring during adalimumab and methotrexate treatment.

  Joint, bone, spine : revue du rhumatisme 20120101

• Generation of high-expressing cells by methotrexate amplification of destabilized dihydrofolate reductase selection marker.

  Methods in molecular biology (Clifton, N.J.) 20120101

• Vogt-Koyanagi-Harada syndrome in a 6-year-old Hispanic boy.

  Pediatric dermatology 20120101

• Comparison of pulsed actinomycin D versus 5-day methotrexate for the treatment of low-risk gestational trophoblastic disease.

  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20120101

• Achieving optimal dose intensity with adjuvant chemotherapy in elderly breast cancer patients: a 10-year retrospective study in a UK institution.

  The breast journal 20120101

• Polymerized-type I collagen induces upregulation of Foxp3-expressing CD4 regulatory T cells and downregulation of IL-17-producing CD4⁺ T cells (Th17) cells in collagen-induced arthritis.

  Clinical & developmental immunology 20120101

• Patterns of interaction between genetic and nongenetic attributes and methotrexate efficacy in rheumatoid arthritis.

  Pharmacogenetics and genomics 20120101

• Bone marrow gold.

  British journal of haematology 20120101

• Choriocarcinoma of the sigmoid colon: report of a case.

  Surgery today 20120101

• Idiopathic inflammation of the orbit and contiguous structures.

  Ophthalmic plastic and reconstructive surgery 20120101

• Febrile ulceronecrotic Mucha-Habermann disease (pityriasis lichenoides et varioliformis acuta fulminans) presenting as Stevens-Johnson syndrome.

  Pediatric dermatology 20120101

• Genetic polymorphisms in metabolic and cellular transport pathway of methotrexate impact clinical outcome of methotrexate monotherapy in Japanese patients with rheumatoid arthritis.

  Drug metabolism and pharmacokinetics 20120101

• Dendrimer-based multivalent methotrexates as dual acting nanoconjugates for cancer cell targeting.

  European journal of medicinal chemistry 20120101

• Adalimumab in budesonide and methotrexate refractory collagenous colitis.

  Scandinavian journal of gastroenterology 20120101

• Giant cell arteritis in Mexican patients.

  Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20120101

• Inflammatory and noninflammatory arthropathy in patients with 18q deletion syndrome.

  Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20120101

• Low-dose methotrexate inhibits methionine S-adenosyltransferase in vitro and in vivo.

  Molecular medicine (Cambridge, Mass.) 20120101

• Still bizarre.

  Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20120101

• Visceral leishmaniasis in a rheumatoid arthritis patient treated with methotrexate.

  Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20120101

• FcγRIIIa expression on monocytes in rheumatoid arthritis: role in immune-complex stimulated TNF production and non-response to methotrexate therapy.

  PloS one 20120101

• Maraviroc, a chemokine receptor-5 antagonist, fails to demonstrate efficacy in the treatment of patients with rheumatoid arthritis in a randomized, double-blind placebo-controlled trial.

  Arthritis research & therapy 20120101

• Methotrexate is an effective and safe adjuvant therapy for pemphigus vulgaris.

  European journal of dermatology : EJD 20120101

• Investigation of nano lipid vesicles of methotrexate for anti-rheumatoid activity.

  International journal of nanomedicine 20120101

• [Fatal pneumonitis during low-dose methotrexate treatment].

  Zeitschrift fur Rheumatologie 20120101

• Efficacy of the CMFVP regimen in patients with metastatic breast cancer previously treated with anthracycline and taxane.

  Onkologie 20120101

• Metronomic chemotherapy in advanced oral cancers.

  Journal of cancer research and therapeutics 20120101

• Association of dihydrofolate reductase (DHFR) -317AA genotype with poor response to methotrexate in patients with rheumatoid arthritis.

  Clinical and experimental rheumatology 20120101

• Interstitial lung disease related to rheumatoid arthritis: evolution after treatment.

  Reumatologia clinica 20120101

• Infection from an exfoliating primary tooth in a child with severe neutropenia: a case report.

  Pediatric dentistry 20120101

• Leflunomide in monotherapy of rheumatoid arthritis: meta-analysis of randomized trials.

  Polskie Archiwum Medycyny Wewnetrznej 20120101

• Refractory polymyalgia rheumatica as presenting manifestation of large-vessel vasculitis associated to sarcoidosis. Successful response to adalimumab.

  Clinical and experimental rheumatology 20120101

• Systematic review of disease-modifying antirheumatic drugs for juvenile idiopathic arthritis.

  BMC pediatrics 20120101

• Structure and dynamics of the G121V dihydrofolate reductase mutant: lessons from a transition-state inhibitor complex.

  PloS one 20120101

• Population analysis of pharmacogenetic polymorphisms related to acute lymphoblastic leukemia drug treatment.

  Disease markers 20120101

• High dose methotrexate and extended hours high-flux hemodialysis for the treatment of primary central nervous system lymphoma in a patient with end stage renal disease.

  American journal of blood research 20120101

• Methotrexate in psoriasis: do we need to give a test dose?

  Actas dermo-sifiliograficas 20120101

• Disruption of the folate pathway in zebrafish causes developmental defects.

  BMC developmental biology 20120101

• [Munchhausen syndrome by proxy revealed by falsely toxic methotrexate levels].

  Annales de biologie clinique 20120101

• What is the future of CCR5 antagonists in rheumatoid arthritis?

  Arthritis research & therapy 20120101

• Pericardial breast cancer metastasis 25 years after mastectomy.

  Tumori 20120101

• A population-based study on the patterns of use of different chemotherapy regimens in Swiss patients with early breast cancer.

  Swiss medical weekly 20120101

• Can the association of Ciclosporine A and Methotrexate maintain remission/low disease activity induced by etanercept in early Rheumatoid Arthritis patients? Evaluation by Magnetic Resonance Imaging.

  International journal of immunopathology and pharmacology 20120101

• The value of BP230 enzyme-linked immunosorbent assay in the diagnosis and immunological follow-up of bullous pemphigoid.

  Dermatology (Basel, Switzerland) 20120101

• [Systemic treatment of ocular cicatricial pemphigoid].

  Medicina 20120101

• Dietary L-arginine supplementation reduces Methotrexate-induced intestinal mucosal injury in rat.

  BMC gastroenterology 20120101

• [Adaptation of methotrexate determination in serum with Unicel DxC600(®)].

  Annales de biologie clinique 20120101

• Beneficial effects of montelukast against methotrexate-induced liver toxicity: a biochemical and histological study.

  TheScientificWorldJournal 20120101

• Low-dose oral prednisone improves clinical and ultrasonographic remission rates in early rheumatoid arthritis: results of a 12-month open-label randomised study.

  Arthritis research & therapy 20120101

• Comprehensive analysis of published phase I/II clinical trials between 1990-2010 in osteosarcoma and Ewing sarcoma confirms limited outcomes and need for translational investment.

  Clinical sarcoma research 20120101

• Clinical significance of cartilage biomarkers for monitoring structural joint damage in rheumatoid arthritis patients treated with anti-TNF therapy.

  PloS one 20120101

• [HPV-associated verrucous carcinoma of the perianal region--complete remission after surgical excision and postoperative monochemotherapy with methotrexat].

  Akusherstvo i ginekologiia 20120101

• Differential response of immunohistochemically defined breast cancer subtypes to anthracycline-based adjuvant chemotherapy with or without paclitaxel.

  PloS one 20120101

• Adenosine receptor expression in rheumatoid synovium: a basis for methotrexate action.

  Arthritis research & therapy 20120101

• A cost analysis of first-line chemotherapy for low-risk gestational trophoblastic neoplasia.

  The Journal of reproductive medicine 20120101

• Importance of salvage therapy in the management of high-risk gestational trophoblastic neoplasia.

  The Journal of reproductive medicine 20120101

• High-risk metastatic gestational trophoblastic neoplasia. Primary management with EMA-CO (etoposide, methotrexate, actinomycin D, cyclophosphamide and vincristine) chemotherapy.

  The Journal of reproductive medicine 20120101

• Survival of women with gestational trophoblastic neoplasia and liver metastases: is it improving?

  The Journal of reproductive medicine 20120101

• A comparison between ozonolysis and sonolysis/ozonolysis treatments for the degradation of the cytostatic drugs methotrexate and doxorubicin: Kinetic and efficiency approaches.

  Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering 20120101

• Interest of high-dose pulse corticosteroid therapy combined with methotrexate for severe alopecia areata: a retrospective case series.

  Dermatology (Basel, Switzerland) 20120101

• Efficacy of leflunomide 100mg weekly compared to low dose methotrexate in patients with active rheumatoid arthritis. Double blind, randomized clinical trial.

  Reumatologia clinica 20120101

• [Organ-preserving interventions in combined therapy of children and adolescents with osteosarcoma].

  Voprosy onkologii 20120101

• Rosai-Dorfman disease treated with methotrexate and low-dose prednisone: case report and review of the literature.

  Journal of cutaneous medicine and surgery 20120101

• First-line chemotherapy in low-risk gestational trophoblastic neoplasia.

  The Cochrane database of systematic reviews 20120101

• Immunomodulatory effect of sertraline in a rat model of rheumatoid arthritis.

  Neuroimmunomodulation 20120101

• Relationship between antimetabolite toxicity and pharmacogenetics in Turkish cancer patients.

  Asian Pacific journal of cancer prevention : APJCP 20120101

• Actinomycin D for methotrexate-failed low-risk gestational trophoblastic neoplasia.

  The Journal of reproductive medicine 20120101

• Ectopic gestational trophoblastic disease: a case series review.

  The Journal of reproductive medicine 20120101

• Clinical epidemiology and management of gestational trophoblastic neoplasia in Hungary in the past 34 years.

  The Journal of reproductive medicine 20120101

• Gestational trophoblastic disease: a 21-year review of the clinical experience at an Argentinean public hospital.

  The Journal of reproductive medicine 20120101

• Systemic juvenile xanthogranuloma with multiple central nervous system lesions.

  Journal of cancer research and therapeutics 20120101

• The hairy-print for levamisole-induced vasculitis.

  BMJ case reports 20120101

• Clinicopathological significance of mesothelin expression in invasive breast cancer.

  The Journal of international medical research 20120101

• Potential role of poly(ADP-ribose) polymerase (PARP) activation in methotrexate-induced nephrotoxicity and tubular apoptosis.

  International journal of toxicology 20120101

• Influenza A H1N1/2009 vaccine in juvenile dermatomyositis: reduced immunogenicity in patients under immunosuppressive therapy.

  Clinical and experimental rheumatology 20120101

• Progress in strategies for dosage regimen individualization.

  Current topics in medicinal chemistry 20120101

• [Single-photon emission computed tomography in the diagnosis of myocardial perfusion abnormalities in patients with rheumatoid arthritis: preliminary data].

  Terapevticheskii arkhiv 20120101

• Association between polymorphisms of dihydrofolate reductase and gamma glutamyl hydrolase genes and toxicity of high dose methotrexate in children with acute lymphoblastic leukemia.

  Asian Pacific journal of cancer prevention : APJCP 20120101

• [Lesions in the nervous system during chemotherapy of acute leukosis and non-Hodgkin lymphomas].

  Klinicheskaia meditsina 20120101

• Levamisole-induced Wegener's granulomatosis following contaminated cocaine abuse.

  Skinmed 20120101

• Eczema herpeticum complicating topical 5-Fluorouracil therapy.

  Dermatitis : contact, atopic, occupational, drug 20120101

• Pharmacogenetic analysis of pediatric patients with acute lymphoblastic leukemia: a possible association between survival rate and ITPA polymorphism.

  PloS one 20120101

• Angioedema of the periorbital region that developed during treatment with etanercept in a case of refractory adult-onset Still's disease.

  Internal medicine (Tokyo, Japan) 20120101

• Induction of hyperchromic microcytic anaemia by repeated oral administration of methotrexate in rats.

  The Journal of toxicological sciences 20120101

• Population PK/PD model of homocysteine concentrations after high-dose methotrexate treatment in patients with acute lymphoblastic leukemia.

  PloS one 20120101

• Granulomatous mastitis complicated by arthralgia and erythema nodosum successfully treated with prednisolone and methotrexate.

  Internal medicine (Tokyo, Japan) 20120101

• Prevention of bone growth defects, increased bone resorption and marrow adiposity with folinic acid in rats receiving long-term methotrexate.

  PloS one 20120101

• The prognostic and predictive value of mRNA expression of vascular endothelial growth factor family members in breast cancer: a study in primary tumors of high-risk early breast cancer patients participating in a randomized Hellenic Cooperative Oncology Group trial.

  Breast cancer research : BCR 20120101

• The molecular basis of folate salvage in Plasmodium falciparum: characterization of two folate transporters.

  The Journal of biological chemistry 20111230

• Preclinical evaluation of pemetrexed in pediatric solid tumors.

  Pediatric blood & cancer 20111215

• Important role of caspase-8 for chemosensitivity of ALL cells.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20111215

• [Gestational trophoblastic neoplasia].

  Orvosi hetilap 20111204

• Insulin-like growth factor-1 receptor inhibitor, AMG-479, in cetuximab-refractory head and neck squamous cell carcinoma.

  Head & neck 20111201

• Cutaneous lupus erythematosus: update of therapeutic options part II.

  Journal of the American Academy of Dermatology 20111201

• Immunoglobulins during different treatment regimes in Schnitzler's syndrome.

  Rheumatology international 20111201

• Treatment of refractory adult-onset Still's disease with tocilizumab: report of two cases and review of the literature.

  Rheumatology international 20111201

• Methotrexate in the treatment of inflammatory bowel disease: an 8-year retrospective study in a Canadian pediatric IBD center.

  Inflammatory bowel diseases 20111201

• Studies of the efficacy and safety of methotrexate at dosages over 8 mg/week using the IORRA cohort database.

  Modern rheumatology 20111201

• Comparison of QuantiFERON-TB Gold and the tuberculin skin test for detecting previous tuberculosis infection evaluated by chest CT findings in Japanese rheumatoid arthritis patients.

  Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20111201

• Inflammatory myopathy in a patient with postural and kinetik tremor.

  Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20111201

• Sclerosing mesenteritis in a child with celiac disease.

  Journal of pediatric gastroenterology and nutrition 20111201

• Current smoking status is associated to a non-ACR 50 response in early rheumatoid arthritis. A cohort study.

  Clinical rheumatology 20111201

• MRI restricted diffusion in lymphomatous optic neuropathy.

  Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society 20111201

• Cord blood transplantation from unrelated donors for children with acute lymphoblastic leukemia in Japan: the impact of methotrexate on clinical outcomes.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20111201

• Novel integrin-targeted binding-triggered drug delivery system for methotrexate.

  Pharmaceutical research 20111201

• Two cases of plasmacytoid variant of urothelial carcinoma of urinary bladder: systemic chemotherapy might be of benefit.

  International journal of clinical oncology 20111201

• Metastatic choriocarcinoma presenting and treated during viable pregnancy: a case report.

  BJOG : an international journal of obstetrics and gynaecology 20111201

• [Multiple warts appearing exclusively on psoriasis plaques].

  Actas dermo-sifiliograficas 20111201

• Donepezil reduces cognitive impairment associated with anti-cancer drugs in a mouse model.

  Neuropharmacology 20111201

• Immunosuppressive treatment in refractory chronic inflammatory demyelinating polyradiculoneuropathy. A nationwide retrospective analysis.

  European journal of neurology 20111201

• [Treatment-resistant adult atopic dermatitis].

  Actas dermo-sifiliograficas 20111201

• Antibody response is reduced following vaccination with 7-valent conjugate pneumococcal vaccine in adult methotrexate-treated patients with established arthritis, but not those treated with tumor necrosis factor inhibitors.

  Arthritis and rheumatism 20111201

• Persistent cognitive deficits, induced by intrathecal methotrexate, are associated with elevated CSF concentrations of excitotoxic glutamate analogs and can be reversed by an NMDA antagonist.

  Behavioural brain research 20111201

• Ofatumumab, a fully human anti-CD20 monoclonal antibody, in biological-naive, rheumatoid arthritis patients with an inadequate response to methotrexate: a randomised, double-blind, placebo-controlled clinical trial.

  Annals of the rheumatic diseases 20111201

• Comparative effectiveness of rituximab in combination with either methotrexate or leflunomide in the treatment of rheumatoid arthritis.

  Seminars in arthritis and rheumatism 20111201

• Underexpression of miR-224 in methotrexate resistant human colon cancer cells.

  Biochemical pharmacology 20111201

• Reduced level of ribonucleotide reductase R2 subunits increases dependence on homologous recombination repair of cisplatin-induced DNA damage.

  Molecular pharmacology 20111201

• The effects of chemotherapeutic agents on differentiated chordoma cells.

  Journal of neurosurgery. Spine 20111201

• 667C>T and 1298A>C polymorphisms of MTHFR do not predict response to methotrexate in patients with gestational trophoblastic neoplasia.

  Gynecologic oncology 20111201

• Retreatment with rituximab based on a treatment-to-target approach provides better disease control than treatment as needed in patients with rheumatoid arthritis: a retrospective pooled analysis.

  Rheumatology (Oxford, England) 20111201

• Exploratory analyses of the association of MRI with clinical, laboratory and radiographic findings in patients with rheumatoid arthritis.

  Annals of the rheumatic diseases 20111201

• Ganoderma lucidum polysaccharides reduce methotrexate-induced small intestinal damage in mice via induction of epithelial cell proliferation and migration.

  Acta pharmacologica Sinica 20111201

• Capecitabine versus classical cyclophosphamide, methotrexate, and fluorouracil as first-line chemotherapy for advanced breast cancer.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20111201

• Caffeic acid phenethyl ester (CAPE) prevents methotrexate-induced hepatorenal oxidative injury in rats.

  The Journal of pharmacy and pharmacology 20111201

• Synthesis, pharmacoscintigraphic evaluation and antitumor efficacy of methotrexate-loaded, folate-conjugated, stealth albumin nanoparticles.

  Nanomedicine (London, England) 20111201

• A case of acute sarcoid myositis treated with weekly low-dose methotrexate.

  Muscle & nerve 20111201

• Development of biomarkers to optimize pediatric patient management: what makes children different?

  Biomarkers in medicine 20111201

• A population pharmacokinetic/pharmacodynamic model of methotrexate and mucositis scores in osteosarcoma.

  Therapeutic drug monitoring 20111201

• [Maintainance treatment of anti-neutrophil cytoplasm associated antibodies (ANCA)].

  Reumatologia clinica 20111201

• Childhood osseous sarcoidosis presenting with headache and lytic skull lesions.

  Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20111201

• [Choice of therapy based on clinical setting].

  Annales de dermatologie et de venereologie 20111201

• Juvenile xanthogranulomatosis with bilateral and multifocal ocular lesions of the iris, cornealscleral limbus, and choroid.

  Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus 20111201

• Pilot study of a pediatric metronomic 4-drug regimen.

  Oncotarget 20111201

• Measurement of methotrexate polyglutamates in human erythrocytes by ion-pair UPLC-MS/MS.

  Bioanalysis 20111201

• Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

  PLoS computational biology 20111201

• Effect of maintenance chemotherapy with gemcitabine and paclitaxel on recurrent squamous cell carcinoma of the bladder: a case report.

  Anticancer research 20111201

• [What's new in dermatological therapy?].

  Annales de dermatologie et de venereologie 20111201

• Protective effect of ellagic acid and pumpkin seed oil against methotrexate-induced small intestine damage in rats.

  Indian journal of biochemistry & biophysics 20111201

• Targeted delivery of methotrexate to tumor cells using biotin functionalized methotrexate-human serum albumin conjugated nanoparticles.

  Journal of biomedical nanotechnology 20111201

• Recurrent parotitis as a first manifestation in a child with primary Sjogren's syndrome.

  The West Indian medical journal 20111201

• Sirolimus and tacrolimus as immune prophylaxis compared to cyclosporine with or without methotrexate in patients undergoing allogeneic haematopoietic stem cell transplantation for non-malignant disorders.

  European journal of haematology 20111201

• Degradable water soluble hyperbranched polymers for drug delivery.

  Journal of controlled release : official journal of the Controlled Release Society 20111130

• Acute methotrexate toxicity seen as plaque psoriasis ulceration and necrosis: A diagnostic clue.

  Dermatology online journal 20111115

• Medical methods for first trimester abortion.

  The Cochrane database of systematic reviews 20111109

• Safety of non-steroidal anti-inflammatory drugs, including aspirin and paracetamol (acetaminophen) in people receiving methotrexate for inflammatory arthritis (rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, other spondyloarthritis).

  The Cochrane database of systematic reviews 20111109

• Rare localizations of bone sarcoidosis: two case reports and review of the literature.

  Rheumatology international 20111101

• Antibodies against cyclic citrullinated peptide don't decrease after 6 months of infliximab treatment in refractory rheumatoid arthritis.

  Rheumatology international 20111101

• Methotrexate toxicity and efficacy during the consolidation phase in paediatric acute lymphoblastic leukaemia and MTHFR polymorphisms as pharmacogenetic determinants.

  Cancer chemotherapy and pharmacology 20111101

• A systematic review of morphea treatments and therapeutic algorithm.

  Journal of the American Academy of Dermatology 20111101

• Disseminated intravascular coagulation as the presenting sign of gastric cancer during pregnancy.

  The journal of obstetrics and gynaecology research 20111101

• Chemotherapeutic adjuvant treatment for osteosarcoma: where do we stand?

  European journal of cancer (Oxford, England : 1990) 20111101

• A case of pityriasis rubra pilaris with associated focal acantholytic dyskeratosis complicated by Kaposi's varicelliform eruption.

  Journal of cutaneous pathology 20111101

• Therapy of polymyositis and dermatomyositis.

  Autoimmunity reviews 20111101

• The cost-effectiveness of adjuvant chemotherapy for early breast cancer: A comparison of no chemotherapy and first, second, and third generation regimens for patients with differing prognoses.

  European journal of cancer (Oxford, England : 1990) 20111101

• Incidental findings on brain Magnetic Resonance Imaging in long-term survivors of breast cancer treated with adjuvant chemotherapy.

  European journal of cancer (Oxford, England : 1990) 20111101

• Medication neurotoxicity in children.

  Pediatric radiology 20111101

• Rheumatoid arthritis near remission: clinical rather than laboratory inflammation is associated with radiographic progression.

  Annals of the rheumatic diseases 20111101

• Premature ovarian failure and body composition changes with adjuvant chemotherapy for breast cancer.

  Menopause (New York, N.Y.) 20111101

• MTHFR 677TT genotype and toxicity of methotrexate: controversial results.

  Cancer chemotherapy and pharmacology 20111101

• Clinical response and tolerability to abatacept in patients with rheumatoid arthritis previously treated with infliximab or abatacept: open-label extension of the ATTEST Study.

  Annals of the rheumatic diseases 20111101

• A rare shock.

  The American journal of medicine 20111101

• Membrane-active host defense peptides--challenges and perspectives for the development of novel anticancer drugs.

  Chemistry and physics of lipids 20111101

• Medical management of Crohn's disease.

  Expert opinion on pharmacotherapy 20111101

• Long-term observational study of sporadic inclusion body myositis.

  Brain : a journal of neurology 20111101

• Aggressive cutaneous infection with Mycobacterium marinum in two patients receiving anti-tumor necrosis factor-alfa agents.

  Journal of the American Academy of Dermatology 20111101

• Adult T-cell lymphoma/leukemia presenting as pagetoid reticulosis of the palms and soles.

  Journal of the American Academy of Dermatology 20111101

• Modern treatment strategies in rheumatoid arthritis.

  Danish medical bulletin 20111101

• Salvage therapy with oral metronomic cyclophosphamide and methotrexate for castration-refractory metastatic adenocarcinoma of the prostate resistant to docetaxel.

  Urology 20111101

• Oxidative effect of methotrexate administration in spinal cord of rabbits.

  JPMA. The Journal of the Pakistan Medical Association 20111101

• Assessment of intracellular methotrexate and methotrexate-polyglutamate metabolite concentrations in erythrocytes by ultrafast matrix-assisted laser desorption/ionization triple quadrupole tandem mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20111030

• Synthesis, biological, and antitumor activity of a highly potent 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl antifolate inhibitor with proton-coupled folate transporter and folate receptor selectivity over the reduced folate carrier that inhibits β-glycinamide ribonucleotide formyltransferase.

  Journal of medicinal chemistry 20111027

• Mitochondrial preprotein translocase of trypanosomatids has a bacterial origin.

  Current biology : CB 20111025

• [Inflammatory bowel disease and lymphoproliferative disorders].

  The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi 20111025

• [Systemic autoimmune disorders and pregnancy].

  Orvosi hetilap 20111023

• Concurrent vs sequential adjuvant chemotherapy and hormone therapy in breast cancer: a multicenter randomized phase III trial.

  Journal of the National Cancer Institute 20111019

• Mycosis fungoides stage IB progressing to cutaneous tumors.

  Dermatology online journal 20111015

• [Pharmacokinetic analysis of high-dose methotrexate treatments in children with hematologic malignancies].

  Orvosi hetilap 20111002

• CHOD/BVAM chemotherapy and whole-brain radiotherapy for newly diagnosed primary central nervous system lymphoma.

  International journal of radiation oncology, biology, physics 20111001

• Effective continuous systemic therapy of severe plaque-type psoriasis is accompanied by amelioration of biomarkers of cardiovascular risk: results of a prospective longitudinal observational study.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20111001

• Long-term results of International Breast Cancer Study Group Trial VIII: adjuvant chemotherapy plus goserelin compared with either therapy alone for premenopausal patients with node-negative breast cancer.

  Annals of oncology : official journal of the European Society for Medical Oncology 20111001

• Hemophagocytic syndrome in a patient with rheumatoid arthritis.

  Modern rheumatology 20111001

• Efficacy and safety of additional use of tacrolimus in patients with early rheumatoid arthritis with inadequate response to DMARDs--a multicenter, double-blind, parallel-group trial.

  Modern rheumatology 20111001

• Imatinib combined with myeloablative allogeneic hematopoietic stem cell transplantation for advanced phases of chronic myeloid leukemia.

  Leukemia research 20111001

• Augmented therapy improves outcome for pediatric high risk acute lymphocytic leukemia: results of Children's Oncology Group trial P9906.

  Pediatric blood & cancer 20111001

• Fludarabine and pharmacokinetic-targeted busulfan before allografting for adults with acute lymphoid leukemia.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20111001

• Polymorphisms of the SLCO1B1 gene predict methotrexate-related toxicity in childhood acute lymphoblastic leukemia.

  Pediatric blood & cancer 20111001

• Concomitant adjuvant chemo-radiation therapy with anthracycline-based regimens in breast cancer: a single centre experience.

  La Radiologia medica 20111001

• Combination therapy consisting of gemcitabine, carboplatin, and docetaxel as an active treatment for advanced urothelial carcinoma.

  International journal of clinical oncology 20111001

• Association of genetic polymorphism in the folate metabolic pathway with methotrexate pharmacokinetics and toxicity in childhood acute lymphoblastic leukaemia and malignant lymphoma.

  European journal of clinical pharmacology 20111001

• Effects of repeated administration of chemotherapeutic agents tamoxifen, methotrexate, and 5-fluorouracil on the acquisition and retention of a learned response in mice.

  Psychopharmacology 20111001

• Evaluation of cutaneous angioimmunoblastic T-cell lymphoma.

  Journal of the American Academy of Dermatology 20111001

• A cross-sectional investigation of chronic exposure to microcystin in relationship to childhood liver damage in the Three Gorges Reservoir Region, China.

  Environmental health perspectives 20111001

• Methotrexate-induced pulmonary toxicity in psoriatic arthritis (PsA): case presentation and literature review.

  Clinical rheumatology 20111001

• Subcutaneous abatacept versus intravenous abatacept: a phase IIIb noninferiority study in patients with an inadequate response to methotrexate.

  Arthritis and rheumatism 20111001

• Therapeutic approaches in the treatment of juvenile dermatomyositis in patients with recent-onset disease and in those experiencing disease flare: an international multicenter PRINTO study.

  Arthritis and rheumatism 20111001

• Implementation of a treat-to-target strategy in very early rheumatoid arthritis: results of the Dutch Rheumatoid Arthritis Monitoring remission induction cohort study.

  Arthritis and rheumatism 20111001

• Case of juvenile localized scleroderma with joint sclerosis and Sjögren's syndrome in a child with precocious puberty.

  The Journal of dermatology 20111001

• Functional gene expression profile underlying methotrexate-induced senescence in human colon cancer cells.

  Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20111001

• Short-course ondansetron for the prevention of methotrexate-induced nausea in children with Crohn disease.

  Journal of pediatric gastroenterology and nutrition 20111001

• Synergistic activity of curcumin with methotrexate in ameliorating Freund's Complete Adjuvant induced arthritis with reduced hepatotoxicity in experimental animals.

  European journal of pharmacology 20111001

• Methotrexate area under the curve as a prognostic factor in primary central nervous system lymphoma treated with immunochemoradiotherapy.

  Leukemia & lymphoma 20111001

• Intrathecal administration of trastuzumab with cytarabine and methotrexate in breast cancer patients with leptomeningeal carcinomatosis.

  Breast (Edinburgh, Scotland) 20111001

• The antiepileptic drugs phenobarbital and carbamazepine reduce transport of methotrexate in rat choroid plexus by down-regulation of the reduced folate carrier.

  Molecular pharmacology 20111001

• Metronomic cyclophosphamide and methotrexate for breast cancer: enhanced efficacy by adding dalteparin and low-dose prednisone?

  Breast (Edinburgh, Scotland) 20111001

• Clinical, radiographic and functional effectiveness of tocilizumab for rheumatoid arthritis patients--REACTION 52-week study.

  Rheumatology (Oxford, England) 20111001

• Update on the management of Crohn's disease.

  Current gastroenterology reports 20111001

• Etoposide, cisplatin-etoposide, methotrexate, actinomycin-D as primary treatment for management of very-high-risk gestational trophoblastic neoplasia.

  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20111001

• Absent 'Window of Opportunity' in smokers with short disease duration. Data from BARFOT, a multicenter study of early rheumatoid arthritis.

  The Journal of rheumatology 20111001

• Mooren's-type ulceration associated with severe hidradenitis suppurativa: a case report and literature review.

  Ocular immunology and inflammation 20111001

• Survey of expert practice and perceptions of the supporting clinical evidence for the management of uveitis-related cataract and cystoid macular oedema.

  Ocular immunology and inflammation 20111001

• Mesenchymal stromal cell function is not affected by drugs used in the treatment of inflammatory bowel disease.

  Cytotherapy 20111001

• Individualized toxicity-titrated 6-mercaptopurine increments during high-dose methotrexate consolidation treatment of lower risk childhood acute lymphoblastic leukaemia. A Nordic Society of Paediatric Haematology and Oncology (NOPHO) pilot study.

  British journal of haematology 20111001

• Promising long-term results with attenuated adverse effects by methotrexate-containing sequential chemoradiation therapy in locally advanced head and neck squamous cell carcinoma.

  Japanese journal of clinical oncology 20111001

• Long-term safety, efficacy and inhibition of radiographic progression with abatacept treatment in patients with rheumatoid arthritis and an inadequate response to methotrexate: 3-year results from the AIM trial.

  Annals of the rheumatic diseases 20111001

• Combination of gemcitabine and paclitaxel is a favorable option for patients with advanced or metastatic urothelial carcinoma previously treated with cisplatin-based chemotherapy.

  Japanese journal of clinical oncology 20111001

• Successful use of tocilizumab in a patient with rheumatoid arthritis following severe pancytopenia during etanercept therapy.

  Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20111001

• Weekly vs. daily administration of oral methotrexate (MTX) for generalized plaque psoriasis: a randomized controlled clinical trial.

  International journal of dermatology 20111001

• Systemic drugs in patients with skin diseases.

  Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia 20111001

• [A case of meningeal carcinomatosis due to gastric cancer treated with intrathecal chemotherapy].

  Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 20111001

• [Treatment of Burkitt lymphoma and Burkitt-like lymphoma].

  [Rinsho ketsueki] The Japanese journal of clinical hematology 20111001

• Prognostic significance of biochemical markers in African Burkitt's lymphoma.

  Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20111001

• Rapid synthesis and in vitro and in vivo evaluation of folic acid derivatives labeled with fluorine-18 for PET imaging of folate receptor-positive tumors.

  Nuclear medicine and biology 20111001

• Primary central nervous system lymphoma presenting as Parinaud syndrome.

  Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 20111001

• Treatment of refractory tumor necrosis factor inhibitor-induced palmoplantar pustulosis: a report of 2 cases.

  Archives of dermatology 20111001

• Effect of genetic polymorphisms in the folate pathway on methotrexate therapy in rheumatic diseases.

  Pharmacogenomics 20111001

• Isolated subcutaneous metastasis of osteosarcoma 5 years after initial diagnosis.

  Journal of pediatric surgery 20111001

• Case of the season: Large B-cell lymphoma involving both breasts.

  Seminars in roentgenology 20111001

• Ondansetron versus granisetron in the prevention of chemotherapy induced nausea and vomiting in children with acute lymphoblastic leukemia.

  Mymensingh medical journal : MMJ 20111001

• Peripheral ulcerative keratitis in a child.

  Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus 20111001

• Changes in cotherapies after initiation of disease-modifying antirheumatic drug therapy in patients with rheumatoid arthritis.

  Arthritis care & research 20111001

• Development of a fluorescently labeled thermostable DHFR for studying conformational changes associated with inhibitor binding.

  Biochemical and biophysical research communications 20110930

• [New therapeutic approaches for polymyositis and dermatomyositis].

  Orvosi hetilap 20110925

• [Therapy for anti-MuSK antibody positive myasthenia gravis].

  Orvosi hetilap 20110925

• Synthesis and antiproliferative evaluation of 3,5-disubstituted 1,2,4-triazoles containing flurophenyl and trifluoromethanephenyl moieties.

  Bioorganic & medicinal chemistry letters 20110915

• Malignancy-associated multicentric reticulohistiocytosis.

  Rheumatology international 20110901

• Rheumatoid arthritis and renal light-chain deposition disease: long-term effectiveness of TNF-α blockade with etanercept.

  International urology and nephrology 20110901

• Serum cystatin C level in patients with rheumatoid arthritis after single infusion of infliximab.

  Rheumatology international 20110901

• Effects of different medical treatments on serum copper, selenium and zinc levels in patients with rheumatoid arthritis.

  Biological trace element research 20110901

• A preliminary experience with the HyperCHiDAM Verona intensive chemotherapy regimen in heavily pretreated refractory Hodgkin's lymphoma.

  Hematological oncology 20110901

• A phase I study of personalized peptide vaccination for advanced urothelial carcinoma patients who failed treatment with methotrexate, vinblastine, adriamycin and cisplatin.

  BJU international 20110901

• Differential efficacy of three cycles of CMF followed by tamoxifen in patients with ER-positive and ER-negative tumors: long-term follow up on IBCSG Trial IX.

  Annals of oncology : official journal of the European Society for Medical Oncology 20110901

• Immunochemotherapy with rituximab, methotrexate, procarbazine, and lomustine for primary CNS lymphoma (PCNSL) in the elderly.

  Annals of oncology : official journal of the European Society for Medical Oncology 20110901

• Clinical importance of Bcl-6-positive non-deep-site involvement in non-HIV-related primary central nervous system diffuse large B-cell lymphoma.

  Journal of neuro-oncology 20110901

• PREPARE trial: a randomized phase III trial comparing preoperative, dose-dense, dose-intensified chemotherapy with epirubicin, paclitaxel, and CMF versus a standard-dosed epirubicin-cyclophosphamide followed by paclitaxel with or without darbepoetin alfa in primary breast cancer--outcome on prognosis.

  Annals of oncology : official journal of the European Society for Medical Oncology 20110901

• PREPARE trial: a randomized phase III trial comparing preoperative, dose-dense, dose-intensified chemotherapy with epirubicin, paclitaxel and CMF versus a standard-dosed epirubicin/cyclophosphamide followed by paclitaxel ± darbepoetin alfa in primary breast cancer--results at the time of surgery.

  Annals of oncology : official journal of the European Society for Medical Oncology 20110901

• Psoriasis in the elderly: from the Medical Board of the National Psoriasis Foundation.

  Journal of the American Academy of Dermatology 20110901

• Quercetin induces apoptosis in the methotrexate-resistant osteosarcoma cell line U2-OS/MTX300 via mitochondrial dysfunction and dephosphorylation of Akt.

  Oncology reports 20110901

• Increased sensitivity to apoptosis induced by methotrexate is mediated by JNK.

  Arthritis and rheumatism 20110901

• Folate-targeted nanoparticles show efficacy in the treatment of inflammatory arthritis.

  Arthritis and rheumatism 20110901

• Increasing dihydrobiopterin causes dysfunction of endothelial nitric oxide synthase in rats in vivo.

  American journal of physiology. Heart and circulatory physiology 20110901

• Aggressive combination drug therapy in very early polyarticular juvenile idiopathic arthritis (ACUTE-JIA): a multicentre randomised open-label clinical trial.

  Annals of the rheumatic diseases 20110901

• pH-Dependent transport of pemetrexed by breast cancer resistance protein.

  Drug metabolism and disposition: the biological fate of chemicals 20110901

• Effects of methotrexate on the expression of the translational isoforms of glucocorticoid receptors α and β: correlation with methotrexate efficacy in rheumatoid arthritis patients.

  Rheumatology (Oxford, England) 20110901

• Multicentric reticulohistiocytosis with elevated cytokine serum levels.

  The Journal of dermatology 20110901

• Diagnostic and therapeutic challenges.

  Retina (Philadelphia, Pa.) 20110901

• Targeted dendrimer chemotherapy in an animal model for head and neck squamous cell carcinoma.

  Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 20110901

• A rare complication of intrathecal methotrexate in a child with acute lymphoblastic leukemia.

  Pediatric hematology and oncology 20110901

• Colchicine or methotrexate, with ursodiol, are effective after 20 years in a subset of patients with primary biliary cirrhosis.

  Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20110901

• Changes in patient characteristics in anti-tumour necrosis factor clinical trials for rheumatoid arthritis: results of an analysis of the literature over the past 16 years.

  Annals of the rheumatic diseases 20110901

• Efficacy and safety of CH-1504, a metabolically stable antifolate, in patients with active rheumatoid arthritis: results of a phase II multicenter randomized study.

  The Journal of rheumatology 20110901

• Importance of timing of gestational exposure to methotrexate for its teratogenic effects when used in setting of misdiagnosis of ectopic pregnancy.

  Fertility and sterility 20110901

• A cohort study to evaluate the effectiveness of laparoscopic-guided local injection of etoposide in the management of women with unruptured tubal pregnancy.

  Fertility and sterility 20110901

• Does the addition of chemotherapy to adjuvant endocrine treatment add any benefit in ER-positive early breast cancer: can we rely on large randomized control trials in the era of personalized medicine?

  Annals of oncology : official journal of the European Society for Medical Oncology 20110901

• Cyclolinopeptide derivatives modify methotrexate-induced suppression of the humoral immune response in mice.

  European journal of medicinal chemistry 20110901

• Relapsing polychondritis with encephalitis.

  Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20110901

• Refractory adult-onset still disease successfully treated with abatacept.

  Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20110901

• Tolerance to drug-induced cell death favours the acquisition of multidrug resistance in Leishmania.

  Cell death & disease 20110901

• Clinical analysis of Chinese limb osteosarcoma patients treated by two combinations of methotrexate, cisplatin, doxorubicin and ifosfamide.

  Asia-Pacific journal of clinical oncology 20110901

• Lupus pernio: sarcoid-specific cutaneous manifestation associated with chronic sarcoid arthropathy.

  Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20110901

• Methotrexate dose delivery is more important than ciclosporin level in graft-versus-host disease prophylaxis following T-replete reduced-intensity sibling allogeneic stem cell transplant.

  International journal of hematology 20110901

• [Autoimmune pancreatitis associated with rheumatoid arthritis: successful combination therapy with steroids and methotrexate].

  Deutsche medizinische Wochenschrift (1946) 20110901

• Protective effect of pentoxyfilline in renal toxicity after methotrexate administration.

  European review for medical and pharmacological sciences 20110901

• Self-assembled enzymatic monolayer directly bound to a gold surface: activity and molecular recognition force spectroscopy studies.

  Journal of the American Chemical Society 20110831

• Management of recurrent head and neck cancer: recent progress and future directions.

  Drugs 20110820

• Novel gene markers of immunosuppressive chemicals in mouse lymph node assay.

  Toxicology letters 20110810

• A case of juvenile idiopathic polyarticular arthritis complicated by IgA deficiency in 22q11 deletion syndrome.

  Rheumatology international 20110801

• Polymorphisms C677T and A1298C in the MTHFR gene in Mexican patients with rheumatoid arthritis treated with methotrexate: implication with elevation of transaminases.

  The pharmacogenomics journal 20110801

• Protective effects of thymoquinone against methotrexate-induced testicular injury.

  Human & experimental toxicology 20110801

• Increasing age at diagnosis and worsening renal function in patients with primary central nervous system lymphoma.

  Journal of neuro-oncology 20110801

• [Unilateral odynophagia in rheumatoid arthritis].

  Laryngo- rhino- otologie 20110801

• Eruptive molluscum contagiosums in a patient with rheumatoid arthritis and lung cancer.

  Rheumatology international 20110801

• Leflunomide or methotrexate? Comparison of clinical efficacy and safety in low socio-economic rheumatoid arthritis patients.

  Modern rheumatology 20110801

• The efficacy and safety of gemcitabine plus cisplatin regimen for patients with advanced urothelial carcinoma after failure of M-VAC regimen.

  International journal of clinical oncology 20110801

• Evaluation of the addition of rituximab to CODOX-M/IVAC for Burkitt's lymphoma: a retrospective analysis.

  Annals of oncology : official journal of the European Society for Medical Oncology 20110801

• A phase II study of biweekly mitomycin C and irinotecan combination therapy in patients with fluoropyrimidine-resistant advanced gastric cancer: a report from the Gastrointestinal Oncology Group of the Japan Clinical Oncology Group (JCOG0109-DI Trial).

  Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 20110801

• Treatment of cutaneous lupus.

  Current rheumatology reports 20110801

• Coexistence of ankylosing spondylitis and rheumatoid arthritis in a female patient.

  Clinical rheumatology 20110801

• Association of the 5-aminoimidazole-4-carboxamide ribonucleotide transformylase gene with response to methotrexate in juvenile idiopathic arthritis.

  Annals of the rheumatic diseases 20110801

• Genotyping of single nucleotide polymorphism in γ-glutamyl hydrolase gene by capillary electrophoresis.

  Electrophoresis 20110801

• Synthesis and recycling of tetrahydrobiopterin in endothelial function and vascular disease.

  Nitric oxide : biology and chemistry 20110801

• Phase II study of tofacitinib (CP-690,550) combined with methotrexate in patients with rheumatoid arthritis and an inadequate response to methotrexate.

  Arthritis care & research 20110801

• Invasive placentation and uterus preserving treatment modalities: a systematic review.

  Archives of gynecology and obstetrics 20110801

• Cardiovascular risk factors in inflammatory arthritis.

  Current opinion in lipidology 20110801

• Heterotopic cesarean scar pregnancy associated with a levonorgestrel-releasing intrauterine device.

  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20110801

• Candida esophagitis as the cause of swallowing disturbances in an 85-year-old patient with myasthenia gravis.

  Zeitschrift fur Gerontologie und Geriatrie 20110801

• Reversible bone marrow necrosis after all-trans retinoic acid induction therapy for acute promyelocytic leukaemia.

  Pathology 20110801

• Superimposed linear psoriasis: low effectiveness of biologic therapy.

  Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia 20110801

• Infantile choriocarcinoma in a neonate with massive liver involvement cured with chemotherapy and liver transplant.

  Journal of pediatric hematology/oncology 20110801

• Intravitreal methotrexate for retinoblastoma.

  Ophthalmology 20110801

• [Against parenteral gold therapy in rheumatoid arthritis].

  Deutsche medizinische Wochenschrift (1946) 20110801

• [Evaluation of pharmacokinetic drug-drug-interactions. Critical considerations of the relevance of pharmacokinetic drug-drug interactions of proton pump inhibitors in self medication].

  Medizinische Monatsschrift fur Pharmazeuten 20110801

• [Efficacy, side effects and blood concentration monitoring of high-dose methotrexate in treatment of 180 children with acute lymphoblastic leukemia].

  Zhongguo shi yan xue ye xue za zhi 20110801

• Homozygosity for the rs9939609T allele of the FTO gene may have protective effect on becoming overweight in survivors of childhood acute lymphoblastic leukaemia.

  Journal of genetics 20110801

• [Methotrexate-related lymphomatoid granulomatosis in a patient with rheumatoid arthritis].

  Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20110801

• Treatment of Crohn's disease with cannabis: an observational study.

  The Israel Medical Association journal : IMAJ 20110801

• [Comparison study on treatment of acute graft-versus-host disease with low-dose methotrexate in combination with low-dose methylprednisolone or standard-dose methylprednisolone].

  Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20110801

• Synergistic effect of low-dose cucurbitacin B and low-dose methotrexate for treatment of human osteosarcoma.

  Cancer letters 20110728

• Effect of the gonadotropin-releasing hormone analogue triptorelin on the occurrence of chemotherapy-induced early menopause in premenopausal women with breast cancer: a randomized trial.

  JAMA 20110720

• High dose methotrexate treatment in children with acute lymphoblastic leukaemia may be optimised by a weight-based dose calculation.

  Pediatric blood & cancer 20110715

• Escalating intravenous methotrexate improves event-free survival in children with standard-risk acute lymphoblastic leukemia: a report from the Children's Oncology Group.

  Blood 20110714

• An aqueous birch leaf extract of Betula pendula inhibits the growth and cell division of inflammatory lymphocytes.

  Journal of ethnopharmacology 20110714

• First-line treatment for primary testicular diffuse large B-cell lymphoma with rituximab-CHOP, CNS prophylaxis, and contralateral testis irradiation: final results of an international phase II trial.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110710

• Infant ependymoma in a 10-year AIEOP (Associazione Italiana Ematologia Oncologia Pediatrica) experience with omitted or deferred radiotherapy.

  International journal of radiation oncology, biology, physics 20110701

• Autologous versus reduced-intensity allogeneic hematopoietic cell transplantation for patients with chemosensitive follicular non-Hodgkin lymphoma beyond first complete response or first partial response.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20110701

• Assessment and management of methotrexate hepatotoxicity in psoriasis patients: report from a consensus conference to evaluate current practice and identify key questions toward optimizing methotrexate use in the clinic.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20110701

• High estrogen receptor expression in early breast cancer: chemotherapy needed to improve RFS?

  Breast cancer research and treatment 20110701

• Methotrexate treatment in juvenile localized scleroderma: a randomized, double-blind, placebo-controlled trial.

  Arthritis and rheumatism 20110701

• Treatment strategies aiming at remission in early rheumatoid arthritis patients: starting with methotrexate monotherapy is cost-effective.

  Rheumatology (Oxford, England) 20110701

• Outcome of patients with seronegative spondyloarthritis continuing sulphasalazine and methotrexate after a short course of infliximab therapy--experience from a tertiary care teaching hospital in South India.

  Clinical rheumatology 20110701

• A retrospective comparison of tacrolimus versus cyclosporine with methotrexate for immunosuppression after allogeneic hematopoietic cell transplantation with mobilized blood cells.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20110701

• Double trouble: therapeutic challenges in patients with both juvenile dermatomyositis and psoriasis.

  Archives of dermatology 20110701

• Keloid formation after syndactyly release in patients with associated macrodactyly: management with methotrexate therapy.

  The Journal of hand surgery, European volume 20110701

• Cytomegalovirus infection in a patient with rheumatoid arthritis on low-dose methotrexate.

  Joint, bone, spine : revue du rhumatisme 20110701

• Expert agreement on EULAR/EUSTAR recommendations for the management of systemic sclerosis.

  The Journal of rheumatology 20110701

• Mitotic activity and bone marrow micrometastases have independent prognostic value in node positive breast cancer patients.

  Breast cancer research and treatment 20110701

• Quenched phosphorescence as alternative detection mode in the chiral separation of methotrexate by electrokinetic chromatography.

  Analytical and bioanalytical chemistry 20110701

• Pneumococcal antibody levels after pneumovax in patients with rheumatoid arthritis on methotrexate.

  Annals of the rheumatic diseases 20110701

• Topoisomerase II alpha protein and responsiveness of breast cancer to adjuvant chemotherapy with CEF compared to CMF in the NCIC CTG randomized MA.5 adjuvant trial.

  Breast cancer research and treatment 20110701

• A mass originating from chronic pyothorax in the pleural cavity.

  American journal of hematology 20110701

• An anti-hapten camelid antibody reveals a cryptic binding site with significant energetic contributions from a nonhypervariable loop.

  Protein science : a publication of the Protein Society 20110701

• Novel folate-hydroxamate based antimetabolites: synthesis and biological evaluation.

  Medicinal chemistry (Shariqah (United Arab Emirates)) 20110701

• Clinical role of FDG PET/CT for methotrexate-related malignant lymphoma.

  Clinical nuclear medicine 20110701

• FDG PET/CT in a patient with spontaneous remission of methotrexate-associated lymphoproliferative disorders after interruption of methotrexate.

  Clinical nuclear medicine 20110701

• Neoadjuvant gemcitabine plus cisplatin for muscle-invasive bladder cancer.

  Japanese journal of clinical oncology 20110701

• Methotrexate and misoprostol teratogenicity: further expansion of the clinical manifestations.

  American journal of medical genetics. Part A 20110701

• Randomized phase III trial (GORTEC 98-03) comparing re-irradiation plus chemotherapy versus methotrexate in patients with recurrent or a second primary head and neck squamous cell carcinoma, treated with a palliative intent.

  Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20110701

• Retropharyngeal abscess from an unusual organism-Kingella denitrificans-in a patient on low-dose methotrexate.

  Ear, nose, & throat journal 20110701

• [Biological therapy in sympathetic ophthalmia refractory to combined immunosuppressive treatment].

  Archivos de la Sociedad Espanola de Oftalmologia 20110701

• Atypical Cogan syndrome mimicking acute rheumatic fever.

  Indian pediatrics 20110701

• [A case of intraocular lymphoma having retinal adverse events associated with intravitreal methotrexate].

  Nippon Ganka Gakkai zasshi 20110701

• Strength capacity in young patients who are receiving maintenance therapy for acute lymphoblastic leukemia: a case-control study.

  Clinics (Sao Paulo, Brazil) 20110701

• [Severe pancytopenia and stomatitis in a patient treated with low-dose methostraxate].

  Praxis 20110622

• Successful treatment of relapsed and refractory extramedullary acute promyelocytic leukemia with tamibarotene.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110620

• Frontline treatment of localized osteosarcoma without methotrexate: results of the St. Jude Children's Research Hospital OS99 trial.

  Cancer 20110615

• Continuous low-dose cyclophosphamide and methotrexate combined with celecoxib for patients with advanced cancer.

  British journal of cancer 20110607

• Vibrational softening of a protein on ligand binding.

  The journal of physical chemistry. B 20110602

• Glucarpidase rescue in a patient with high-dose methotrexate-induced nephrotoxicity.

  Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners 20110601

• Rheumatoid arthritis in patient with homozygous haemoglobin C disease.

  Rheumatology international 20110601

• Efficacy study of vesicular gel containing methotrexate and menthol combination on parakeratotic rat skin model.

  Journal of liposome research 20110601

• Low-dose MTX combined with low-dose methylprednisolone as a first-line therapy for the treatment of acute GVHD: safety and feasibility.

  Bone marrow transplantation 20110601

• Timing of radiotherapy and outcome in patients receiving adjuvant endocrine therapy.

  International journal of radiation oncology, biology, physics 20110601

• Long-term results of a randomized trial on the sequencing of radiotherapy and chemotherapy in breast cancer.

  American journal of clinical oncology 20110601

• Prophylaxis with sirolimus and tacrolimus ± antithymocyte globulin reduces the risk of acute graft-versus-host disease without an overall survival benefit following allogeneic stem cell transplantation.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20110601

• Treatment of psoriasis in patients with hepatitis C virus infection.

  Clinical and experimental dermatology 20110601

• A multicentre trial of bucillamine in the treatment of early rheumatoid arthritis (SNOW study).

  Modern rheumatology 20110601

• Relapsing polychondritis: a description of a case and review article.

  Rheumatology international 20110601

• The effect of cerebral spinal fluid replacement on acute myelopathy induced by intrathecal therapy of leukemia.

  Leukemia research 20110601

• Cellular elements of the subarachnoid space promote ALL survival during chemotherapy.

  Leukemia research 20110601

• Treatment with hyperfractionated cyclophosphamide, vincristine, doxorubicin, and dexamethasone combined with cytarabine and methotrexate results in poor mobilization of peripheral blood stem cells in patients with mantle cell lymphoma.

  Leukemia & lymphoma 20110601

• Disclosing the mysteries of the central nervous system sanctuary for acute lymphoblastic leukemia cells.

  Leukemia research 20110601

• Clinical course of Crohn's disease following treatment of lymphoma.

  Inflammatory bowel diseases 20110601

• Folate fortification and survival of children with acute lymphoblastic leukemia.

  Paediatric drugs 20110601

• Dihydrofolate reductase protects endothelial nitric oxide synthase from uncoupling in tetrahydrobiopterin deficiency.

  Free radical biology & medicine 20110601

• Treatment outcome of Korean patients with localized Ewing sarcoma family of tumors: a single institution experience.

  Japanese journal of clinical oncology 20110601

• Certolizumab pegol plus methotrexate provides broad relief from the burden of rheumatoid arthritis: analysis of patient-reported outcomes from the RAPID 2 trial.

  Annals of the rheumatic diseases 20110601

• The impact of four dynamic, goal-steered treatment strategies on the 5-year outcomes of rheumatoid arthritis patients in the BeSt study.

  Annals of the rheumatic diseases 20110601

• Transcatheter arterial chemoembolization versus systemic methotrexate for the management of cesarean scar pregnancy.

  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20110601

• Age differences in temporal discounting: the role of dispositional affect and anticipated emotions.

  Psychology and aging 20110601

• Effects of methylenetetrahydrofolate reductase gene polymorphisms on toxicities during consolidation therapy in pediatric acute lymphoblastic leukemia in a Chinese population.

  Leukemia & lymphoma 20110601

• Design, synthesis, biological evaluation and X-ray crystal structure of novel classical 6,5,6-tricyclic benzo[4,5]thieno[2,3-d]pyrimidines as dual thymidylate synthase and dihydrofolate reductase inhibitors.

  Bioorganic & medicinal chemistry 20110601

• High-dose methotrexate with R-CHOP therapy for the treatment of patients with primary central nervous system lymphoma.

  International journal of hematology 20110601

• Female patients suffering from inflammatory bowel diseases are treated less frequently with immunosuppressive medication and have a higher disease activity: a subgroup analysis of a large multi-centre, prospective, internet-based study.

  Journal of Crohn's & colitis 20110601

• Atypical fractures of the femur and ulna and complications of fracture healing in a 76-year-old woman with Sjögren's syndrome.

  Journal of musculoskeletal & neuronal interactions 20110601

• Treatment of young children with localized medulloblastoma by chemotherapy alone: results of the prospective, multicenter trial HIT 2000 confirming the prognostic impact of histology.

  Neuro-oncology 20110601

• Association between tongue appearance in Traditional Chinese Medicine and effective response in treatment of rheumatoid arthritis.

  Complementary therapies in medicine 20110601

• Immunosuppressive and cytotoxic therapy: pharmacology, toxicities, and monitoring.

  Seminars in respiratory and critical care medicine 20110601

• [A case of gastric cancer accompanied by disseminated carcinomatosis of bone marrow with DIC, and subdural hematoma successfully treated with sequential methotrexate and 5-fluorouracil therapy].

  Gan to kagaku ryoho. Cancer & chemotherapy 20110601

• [Recommendations on the management of psoriatic arthritis].

  Annales de dermatologie et de venereologie 20110601

• Efficacy of adalimumab in patients with Crohn's disease and failure to infliximab therapy: a clinical series.

  Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva 20110601

• Numb chin syndrome in acute lymphoblastic leukemia.

  Indian pediatrics 20110601

• The Peters anomaly following antenatal exposure to methotrexate and hydroxychloroquine.

  Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 20110601

• No deleterious effect of low dose methotrexate on titanium implant osseointegration in a rabbit model.

  Clinics (Sao Paulo, Brazil) 20110601

• A novel effective therapy for refractory angiosarcoma of the face and scalp.

  Clinical advances in hematology & oncology : H&O 20110601

• [Idiopathic granulomatous mastitis treated with steroids and methotrexate].

  Ginecologia y obstetricia de Mexico 20110601

• In vitro risk assessment of AZD9056 perpetrating a transporter-mediated drug-drug interaction with methotrexate.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20110518

• Permeation modulating properties of natural polymers--effect of molecular weight and mucus.

  International journal of pharmaceutics 20110516

• Determination of methotrexate and indomethacin in urine using SPE-LC-DAD after derivatization.

  Journal of pharmaceutical and biomedical analysis 20110515

• Methotrexate for high-grade osteosarcoma in children and young adults.

  The Cochrane database of systematic reviews 20110511

• [Standard CHOP immuno-chemotherapy for primary mediastinal lymphomas].

  Orvosi hetilap 20110508

• High dose methotrexate for pediatric high grade glioma: results of the HIT-GBM-D pilot study.

  Journal of neuro-oncology 20110501

• Fludarabine-based conditioning chemotherapy for allogeneic hematopoietic stem cell transplantation in acquired severe aplastic anemia.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20110501

• Bladder preservation multimodality therapy as an alternative to radical cystectomy for treatment of muscle invasive bladder cancer.

  BJU international 20110501

• Effects of polyphenols from seed shells of Japanese horse chestnut (Aesculus turbinata BLUME) on methotrexate-induced intestinal injury in rats.

  The Journal of veterinary medical science 20110501

• Fluoxetine reverses the memory impairment and reduction in proliferation and survival of hippocampal cells caused by methotrexate chemotherapy.

  Psychopharmacology 20110501

• Plasma creatine phosphokinase level may predict successful treatment after a single injection of methotrexate for ectopic pregnancy.

  Fertility and sterility 20110501

• Adenosine abolishes MTX-induced suppression of osteoclastogenesis and inflammatory bone destruction in adjuvant-induced arthritis.

  Laboratory investigation; a journal of technical methods and pathology 20110501

• Treatment strategies in recent onset rheumatoid arthritis.

  Current opinion in rheumatology 20110501

• Evaluation of trastuzumab without chemotherapy as a post-operative adjuvant therapy in HER2-positive elderly breast cancer patients: randomized controlled trial [RESPECT (N-SAS BC07)].

  Japanese journal of clinical oncology 20110501

• Paclitaxel and cisplatin chemotherapy for metastatic urothelial carcinoma after failure of two courses of platinum-based regimens.

  International journal of urology : official journal of the Japanese Urological Association 20110501

• Methotrexate versus leflunomide in rheumatoid arthritis: what is new in 2011?

  Current opinion in rheumatology 20110501

• Evidence-based recommendations on conventional systemic treatments in psoriasis: systematic review and expert opinion of a panel of dermatologists.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20110501

• Methotrexate in psoriasis: a systematic review of treatment modalities, incidence, risk factors and monitoring of liver toxicity.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20110501

• Paraplegia and paraparesis from intrathecal methotrexate and cytarabine contaminated with trace amounts of vincristine in China during 2007.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110501

• Update 2011: leflunomide in rheumatoid arthritis - strengths and weaknesses.

  Current opinion in rheumatology 20110501

• A review of phototherapy protocols for psoriasis treatment.

  Journal of the American Academy of Dermatology 20110501

• Shortening infusion time for high-dose methotrexate alters antileukemic effects: a randomized prospective clinical trial.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110501

• [Cutaneous cytotoxic T-cell lymphoma].

  Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20110501

• Evidence for methotrexate as a useful treatment for steroid-dependent chronic urticaria.

  Acta dermato-venereologica 20110501

• Mastocytic enterocolitis as a rare cause of chronic diarrhea in a patient with rheumatoid arthritis.

  Wiener klinische Wochenschrift 20110501

• The plastidial folylpolyglutamate synthetase and root apical meristem maintenance.

  Plant signaling & behavior 20110501

• [Intravascular large B-cell lymphoma: an important cause of fever of unknown origin].

  Brain and nerve = Shinkei kenkyu no shinpo 20110501

• [Treatment strategy for central nervous system involvement in intravascular large B-cell lymphoma].

  Brain and nerve = Shinkei kenkyu no shinpo 20110501

• Have advances in extracorporeal removal techniques changed the indications for their use in poisonings?

  Advances in chronic kidney disease 20110501

• Comparison of single-dose and two-dose methotrexate protocols for the treatment of unruptured ectopic pregnancy.

  Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 20110501

• [Bullous pemphigoid and acquired haemophilia].

  Annales de dermatologie et de venereologie 20110501

• Dermatomyositis and pemphigus vulgaris: association or coincidence?

  The Australasian journal of dermatology 20110501

• Metastatic malignant melanoma and dermatomyositis: A paraneoplastic phenomenon.

  The Australasian journal of dermatology 20110501

• [News on psoriasis from the 2010 Dermatology Days in Paris].

  Annales de dermatologie et de venereologie 20110501

• [A case of primary urothelial carcinoma of the prostate responsive to MVAC intra-arterial chemotherapy: a case report].

  Hinyokika kiyo. Acta urologica Japonica 20110501

• Identification of drug targets in vitro and in living cells by soluble-nanopolymer-based proteomics.

  Angewandte Chemie (International ed. in English) 20110426

• Sildenafil reverses ABCB1- and ABCG2-mediated chemotherapeutic drug resistance.

  Cancer research 20110415

• Polyvalent saccharide-functionalized generation 3 poly(amidoamine) dendrimer-methotrexate conjugate as a potential anticancer agent.

  Bioorganic & medicinal chemistry 20110415

• Addition of pamidronate to chemotherapy for the treatment of osteosarcoma.

  Cancer 20110415

• Ustekinumab treats psoriasis refractory to seven conventional and biologic therapies.

  Dermatology online journal 20110415

• Gemcitabine for unresectable, locally advanced or metastatic bladder cancer.

  The Cochrane database of systematic reviews 20110413

• A comparison of an interferon-gamma release assay and tuberculin skin test in refractory inflammatory disease patients screened for latent tuberculosis prior to the initiation of a first tumor necrosis factor α inhibitor.

  Clinical rheumatology 20110401

• Etanercept plus ciclosporin versus etanercept plus methotrexate for maintaining clinical control over psoriatic arthritis: a randomised pilot study.

  Annals of the rheumatic diseases 20110401

• Attenuation of arthritis in rodents by a novel orally-available inhibitor of sphingosine kinase.

  Inflammopharmacology 20110401

• Coding polypurine hairpins cause target-induced cell death in breast cancer cells.

  Human gene therapy 20110401

• Efficacy and tolerability of tocilizumab in rheumatoid arthritis patients seen in daily clinical practice in Japan: results from a retrospective study (REACTION study).

  Modern rheumatology 20110401

• The incidence of symptomatic thromboembolism in patients receiving adjuvant anthracycline-based chemotherapy for early stage breast cancer.

  Breast (Edinburgh, Scotland) 20110401

• Skeletal imaging effects of pamidronate therapy in osteosarcoma patients.

  Pediatric radiology 20110401

• Atypical generalized morphea-like scleroderma presenting deep sclerosis on the fingers.

  Modern rheumatology 20110401

• The treatment of rheumatoid arthritis during pregnancy.

  Rheumatology international 20110401

• Reduction of Fas/CD95 promoter methylation, upregulation of Fas protein, and enhancement of sensitivity to apoptosis in cutaneous T-cell lymphoma.

  Archives of dermatology 20110401

• Fumarates vs. methotrexate in moderate to severe chronic plaque psoriasis: a multicentre prospective randomized controlled clinical trial.

  The British journal of dermatology 20110401

• Practice patterns in the use of anti-tumor necrosis factor alpha agents in the management of Crohn's disease: a US national practice survey comparing experts and non-experts.

  Digestive diseases and sciences 20110401

• [Plasmacytoid dendritic cell tumor].

  Actas dermo-sifiliograficas 20110401

• Paternal exposure to methotrexate and pregnancy outcomes.

  The Journal of rheumatology 20110401

• Disease activity score-driven therapy versus routine care in patients with recent-onset active rheumatoid arthritis: data from the GUEPARD trial and ESPOIR cohort.

  Annals of the rheumatic diseases 20110401

• Five Chinese pediatric patients with leukemias possibly arising from immature natural killer cells: clinical features and courses.

  Pediatric hematology and oncology 20110401

• Tocilizumab: is there life beyond anti-TNF blockade?

  International journal of clinical practice 20110401

• Long-term results of AIEOP-8805 protocol for acute B-cell lymphoblastic leukemia of childhood.

  Pediatric blood & cancer 20110401

• Treatment of children with B-cell non-Hodgkin lymphoma in a low-income country.

  Pediatric blood & cancer 20110401

• Review article: remission rates achievable by current therapies for inflammatory bowel disease.

  Alimentary pharmacology & therapeutics 20110401

• Congenital cardiac defects: a possible association of aminopterin syndrome and in utero methotrexate exposure?

  Pediatric cardiology 20110401

• Impact of concomitant use of DMARDs on the persistence with anti-TNF therapies in patients with rheumatoid arthritis: results from the British Society for Rheumatology Biologics Register.

  Annals of the rheumatic diseases 20110401

• Efficacy of immunosuppressive therapy for inflammatory bowel disease: a systematic review and meta-analysis.

  The American journal of gastroenterology 20110401

• Autism Speaks: meeting on folate metabolism and Autism spectrum disorders, March 19-20, 2009, Washington, DC.

  Journal of pediatric hematology/oncology 20110401

• What is new HLA-B27 acute anterior uveitis?

  Ocular immunology and inflammation 20110401

• Results of the Scandinavian Sarcoma Group XIV protocol for classical osteosarcoma: 63 patients with a minimum follow-up of 4 years.

  Acta orthopaedica 20110401

• Neoadjuvant and adjuvant chemotherapy of cervical cancer: mature results of the phase 2 PBM-PFU protocol.

  International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20110401

• Comparison of APPI, APCI and ESI for the LC-MS/MS analysis of bezafibrate, cyclophosphamide, enalapril, methotrexate and orlistat in municipal wastewater.

  Journal of mass spectrometry : JMS 20110401

• Methotrexate chronotherapy is effective against rheumatoid arthritis.

  Chronobiology international 20110401

• Inhibitory effect of selective cyclooxygenase-2 inhibitor etoricoxib on human organic anion transporter 3 (hOAT3).

  Drug metabolism letters 20110401

• Factors influencing the response to high dose methotrexate-based vincristine and procarbazine combination chemotherapy for primary central nervous system lymphoma.

  Journal of Korean medical science 20110401

• Unresectable multifocal omental and peritoneal inflammatory myofibroblastic tumor in a child: revisiting the role of adjuvant therapy.

  Journal of pediatric surgery 20110401

• [Successful withdrawal from disseminated intravascular coagulation caused by disseminated carcinomatosis of bone marrow originated from gastric cancer treated by sequential therapy consisting of MTX and 5-FU and palliative radiotherapy].

  Gan to kagaku ryoho. Cancer & chemotherapy 20110401

• APEX microarray panel for genotyping polymorphisms in cancer chemotherapy and estimation frequencies in a Slovak population.

  Pharmacogenomics 20110401

• [Survival of breast cancers patients with meningeal carcinoma].

  Bulletin du cancer 20110401

• [Update on psoriasis at the Dermatology Day conference, Paris 2010].

  Annales de dermatologie et de venereologie 20110401

• [The importance of pharmacogenetic tests in evaluation of the effectiveness of methotrexate treatment in rheumatoid arthritis (part 2)].

  Postepy higieny i medycyny doswiadczalnej (Online) 20110330

• In situ evaluation of anticancer drug methotrexate-DNA interaction using a DNA-electrochemical biosensor and AFM characterization.

  Physical chemistry chemical physics : PCCP 20110328

• Protective effect of calcium folinate against methotrexate-induced endosalpinx damage in rats.

  Fertility and sterility 20110315

• Quality of life of older patients with early-stage breast cancer receiving adjuvant chemotherapy: a companion study to cancer and leukemia group B 49907.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110310

• Transient iatrogenic immunodeficiency-related B-cell lymphoproliferative disorder of the skin in a patient with mycosis fungoides/Sézary syndrome.

  Journal of cutaneous pathology 20110301

• Borreliosis in a patient treated with anti-TNFα therapy: first case.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20110301

• A mathematical model of breast cancer treatment with CMF and doxorubicin.

  Bulletin of mathematical biology 20110301

• Spinal cord compression by epidural involvement over 21 vertebral levels in acute lymphoblastic leukemia.

  Journal of pediatric hematology/oncology 20110301

• Treatment of acute promyelocytic leukaemia in the Jehovah's Witness population.

  Annals of hematology 20110301

• The change of bone mineral density according to treatment agents in patients with ankylosing spondylitis.

  Joint, bone, spine : revue du rhumatisme 20110301

• Primary mediastinal B-cell lymphoma treated with CHOP-like chemotherapy with or without rituximab: results of the Mabthera International Trial Group study.

  Annals of oncology : official journal of the European Society for Medical Oncology 20110301

• A pediatric B lineage leukemia with coincident MYC and MLL translocations.

  Journal of pediatric hematology/oncology 20110301

• Midtreatment 18F-fluorodeoxyglucose positron-emission tomography in aggressive non-Hodgkin lymphoma.

  Cancer 20110301

• Preparation, characterization of hydrophilic and hydrophobic drug in combine loaded chitosan/cyclodextrin nanoparticles and in vitro release study.

  Colloids and surfaces. B, Biointerfaces 20110301

• Iatrogenic oral hairy leukoplakia: report of two cases.

  Journal of cutaneous pathology 20110301

• The role of standard-dose cytarabine in children with acute promyelocytic leukemia: a single-center experience.

  Journal of pediatric hematology/oncology 20110301

• Methotrexate- and/or cytarabine-based chemotherapy may be effective and safe in solid-organ transplant recipients with primary central nervous system lymphomas.

  Leukemia & lymphoma 20110301

• Predictors of response to methotrexate in early DMARD naive rheumatoid arthritis: results from the initial open-label phase of the SWEFOT trial.

  Annals of the rheumatic diseases 20110301

• Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.

  Drug metabolism and disposition: the biological fate of chemicals 20110301

• Rheumatoid nodule and combined pulmonary carcinoma: topographic correlations; a case report and review of the literature.

  Histology and histopathology 20110301

• High-dose methotrexate-induced renal dysfunction: is glucarpidase necessary for rescue?

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110301

• Conservative management of cervical ectopic pregnancy: utility of uterine artery embolization.

  Fertility and sterility 20110301

• Imaging colon cancer response following treatment with AZD1152: a preclinical analysis of [18F]fluoro-2-deoxyglucose and 3'-deoxy-3'-[18F]fluorothymidine imaging.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20110301

• AMPK and Akt determine apoptotic cell death following perturbations of one-carbon metabolism by regulating ER stress in acute lymphoblastic leukemia.

  Molecular cancer therapeutics 20110301

• Treatment of low-risk gestational trophoblastic neoplasia.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110301

• Phase III trial of weekly methotrexate or pulsed dactinomycin for low-risk gestational trophoblastic neoplasia: a gynecologic oncology group study.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110301

• Breast cancer: adjuvant modalities.

  Clinical obstetrics and gynecology 20110301

• Ultraviolet light-induced Köbner phenomenon contributes to the development of skin eruptions in multicentric reticulohistiocytosis.

  Acta dermato-venereologica 20110301

• Serum hepcidin and prohepcidin concentrations in inflammatory bowel disease.

  European journal of gastroenterology & hepatology 20110301

• Ovarian involvement of epithelioid trophoblastic tumor: a case report.

  International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 20110301

• Ectopic pregnancy: using the hCG ratio to select women for expectant or medical management.

  Acta obstetricia et gynecologica Scandinavica 20110301

• Reactive tonsillar enlargement with strong 18F-FDG uptake after chemotherapy for tonsillar diffuse large B-cell lymphoma.

  Journal of pediatric hematology/oncology 20110301

• Saline breast implant fluid collection and reactive arthritis in a patient with streptococcal toxic shock syndrome.

  Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20110301

• Concomitant Castleman's disease and sarcoidosis.

  The American journal of the medical sciences 20110301

• Severe hypoglycemic seizures in a child receiving 6-mercaptopurine.

  Journal of pediatric hematology/oncology 20110301

• Clinical relevance of the dose of cytarabine in the upfront treatment of primary CNS lymphomas with methotrexate-cytarabine combination.

  The oncologist 20110301

• Long-term survivals of stage IIb osteosarcoma: a 20-year experience in a single institution.

  Clinics in orthopedic surgery 20110301

• VSL#3 and remission in active ulcerative colitis: larger studies required.

  The American journal of gastroenterology 20110301

• Diffuse infiltrating retinoblastoma with central nervous system metastasis.

  Archives of ophthalmology (Chicago, Ill. : 1960) 20110301

• Towards personalized medicine - the role of methotrexate.

  The Indian journal of medical research 20110301

• Central neurotoxicity in cancer chemotherapy: pharmacogenetic insights.

  Pharmacogenomics 20110301

• Clinical pharmacogenetics of methotrexate.

  Current drug metabolism 20110301

• Undifferentiated connective tissue disease with pulmonary involvement.

  The Journal of the Association of Physicians of India 20110301

• Re: Topoisomerase II alpha and responsiveness of breast cancer to adjuvant chemotherapy.

  Journal of the National Cancer Institute 20110216

• Twelfth biannual report of the Cochrane Haematological Malignancies Group--focus on tyrosine kinase inhibitors.

  Journal of the National Cancer Institute 20110216

• Methotrexate induces apoptosis through p53/p21-dependent pathway and increases E-cadherin expression through downregulation of HDAC/EZH2.

  Biochemical pharmacology 20110215

• Magnetic microparticles based on natural polymers.

  International journal of pharmaceutics 20110214

• Dihydrofolate reductase deficiency due to a homozygous DHFR mutation causes megaloblastic anemia and cerebral folate deficiency leading to severe neurologic disease.

  American journal of human genetics 20110211

• Jessner-Kanof disease induced by leflunomide: a dermal variant of cutaneous lupus?

  Rheumatology international 20110201

• Intralesional agents in the management of cutaneous malignancy: a review.

  Journal of the American Academy of Dermatology 20110201

• Bilateral acute angle-closure associated with systemic lymphoma: a report of 2 cases.

  Journal of glaucoma 20110201

• Prolonged survival of neoplastic meningitis from breast cancer with letrozole and intrathecal methotrexate: a case report.

  Journal of neuro-oncology 20110201

• Neurological picture. Vertebral sarcoidosis mimicking metastases.

  Journal of neurology, neurosurgery, and psychiatry 20110201

• Efficacy of high-dose methotrexate, ifosfamide, etoposide and dexamethasone salvage therapy for recurrent or refractory childhood malignant lymphoma.

  Annals of oncology : official journal of the European Society for Medical Oncology 20110201

• Successful treatment of steroid-resistant methotrexate-induced interstitial pneumonia with peripherally administered ulinastatin.

  Modern rheumatology 20110201

• British isles survey of methotrexate monitoring practice during treatment of juvenile idiopathic arthritis.

  Seminars in arthritis and rheumatism 20110201

• Certolizumab pegol in the treatment of rheumatoid arthritis: a comprehensive review of its clinical efficacy and safety.

  Rheumatology (Oxford, England) 20110201

• Early onset systemic lupus erythematosus: differential diagnoses, clinical presentation, and treatment options.

  Clinical rheumatology 20110201

• Enhancing percutaneous delivery of methotrexate using different types of surfactants.

  Colloids and surfaces. B, Biointerfaces 20110201

• Behçet disease presenting with frosted branch angiitis.

  Ocular immunology and inflammation 20110201

• Taxane-based regimens as a risk factor for chemotherapy-induced amenorrhea.

  Menopause (New York, N.Y.) 20110201

• Effect of atorvastatin on inflammation and modification of vascular risk factors in rheumatoid arthritis.

  The Journal of rheumatology 20110201

• Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.

  Drug metabolism and disposition: the biological fate of chemicals 20110201

• Discontinuing treatment in patients with rheumatoid arthritis in sustained clinical remission: exploratory analyses from the BeSt study.

  Annals of the rheumatic diseases 20110201

• Chemotherapy for thymic tumors: induction, consolidation, palliation.

  Thoracic surgery clinics 20110201

• Factors associated with radiographic progression in patients with rheumatoid arthritis who were treated with methotrexate.

  The Journal of rheumatology 20110201

• Lactose maldigestion during methotrexate-induced gastrointestinal mucositis in a rat model.

  American journal of physiology. Gastrointestinal and liver physiology 20110201

• Pathophysiology of articular chondrocalcinosis--role of ANKH.

  Nature reviews. Rheumatology 20110201

• Randomized phase III trial of adjuvant epirubicin followed by cyclophosphamide, methotrexate, and 5-fluorouracil (CMF) versus CMF followed by epirubicin in patients with node-negative or 1-3 node-positive rapidly proliferating breast cancer.

  Breast cancer research and treatment 20110201

• Older age of rheumatoid arthritis onset is associated with higher activation status of peripheral blood CD4(+) T cells and disease activity.

  Clinical and experimental immunology 20110201

• Autoimmune inner ear disease in children.

  Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 20110201

• Evaluating performance of a decision support system to improve methotrexate pharmacotherapy in children and young adults with cancer.

  Therapeutic drug monitoring 20110201

• Neoadjuvant chemotherapy and concomitant trastuzumab in breast cancer: a pooled analysis of two randomized trials.

  Anti-cancer drugs 20110201

• Influence of polymorphisms within the methotrexate pathway genes on the toxicity and efficacy of methotrexate in patients with juvenile idiopathic arthritis.

  British journal of clinical pharmacology 20110201

• Interactions between detoxification mechanisms and excretion in Malpighian tubules of Drosophila melanogaster.

  The Journal of experimental biology 20110201

• Nail psoriasis successfully treated with intralesional methotrexate: case report.

  Dermatology (Basel, Switzerland) 20110201

• Modulated pharmacokinetics and increased small intestinal toxicity of methotrexate in bilirubin-treated rats.

  The Journal of pharmacy and pharmacology 20110201

• Update on morphea: part II. Outcome measures and treatment.

  Journal of the American Academy of Dermatology 20110201

• Results of the Japan Association of Childhood Leukemia Study (JACLS) NHL-98 protocol for the treatment of B-cell non-Hodgkin lymphoma and mature B-cell acute lymphoblastic leukemia in childhood.

  Leukemia & lymphoma 20110201

• Adenosine deaminase and C-reactive protein in diagnosing and monitoring of rheumatoid arthritis.

  Medicinski glasnik : official publication of the Medical Association of Zenica-Doboj Canton, Bosnia and Herzegovina 20110201

• [The future of methotrexate therapy and other folate inhibitors].

  Zeitschrift fur Rheumatologie 20110201

• [Pharmacogenetics and pharmacogenomics of methotrexate. Current status and novel aspects].

  Zeitschrift fur Rheumatologie 20110201

• Synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO) syndrome with review of the relevant published work.

  The Journal of dermatology 20110201

• Leflunomide in Pakistani patients with rheumatoid arthritis: prospective study in daily rheumatology practice.

  International journal of rheumatic diseases 20110201

• A global approach to psoriatic patients through PASI score and Skindex-29.

  Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia 20110201

• Cyclosporin combined with methotrexate in two patients with recalcitrant subacute cutaneous lupus erythematosus.

  The Australasian journal of dermatology 20110201

• [Interstitial mycosis fungoid: a rare variant of mycosis fungoids. Two cases].

  Annales de pathologie 20110201

• Protective role of lipoic acid on methotrexate induced intestinal damage in rabbit model.

  Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology 20110201

• Intracellular drug delivery of layered double hydroxide nanoparticles.

  Journal of nanoscience and nanotechnology 20110201

• A case of acute methotrexate toxicity.

  Annals of the Academy of Medicine, Singapore 20110201

• [Extra-uterine pregnancy].

  La Revue du praticien 20110201

• Post-chikungunya chronic arthritis--our experience with DMARDs over two year follow up.

  The Journal of the Association of Physicians of India 20110201

• Immunosuppressive therapy in children.

  Journal of the Indian Medical Association 20110201

• Prophylaxis of graft-versus-host disease in unrelated donor transplantation with pentostatin, tacrolimus, and mini-methotrexate: a phase I/II controlled, adaptively randomized study.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110120

• Single agent and combination studies of pralatrexate and molecular correlates of sensitivity.

  British journal of cancer 20110118

• Subcellular localization and distribution of the reduced folate carrier in normal rat tissues.

  European journal of histochemistry : EJH 20110118

• Methotrexate is highly potent against pyrimethamine-resistant Plasmodium vivax.

  The Journal of infectious diseases 20110115

• Spleen tyrosine kinase (Syk) inhibitor for rheumatoid arthritis.

  The New England journal of medicine 20110106

• Erythroblastic islands.

  Blood 20110106

• A case of uterine pseudoaneurysm combined with gestational trophoblastic disease in a 30-year-old woman.

  Minimally invasive therapy & allied technologies : MITAT : official journal of the Society for Minimally Invasive Therapy 20110101

• BRCA1 mRNA expression and outcome to neoadjuvant cisplatin-based chemotherapy in bladder cancer.

  Annals of oncology : official journal of the European Society for Medical Oncology 20110101

• Associations of disease activity and treatments with mortality in men with rheumatoid arthritis: results from the VARA registry.

  Rheumatology (Oxford, England) 20110101

• Use of rituximab in combination with high-dose methotrexate in the treatment of primary central nervous system lymphoma in a mycophenolate mofetil treated patient with lupus nephritis.

  Acta oncologica (Stockholm, Sweden) 20110101

• Gestational trophoblastic disease II: classification and management of gestational trophoblastic neoplasia.

  American journal of obstetrics and gynecology 20110101

• Effect of intra-articular corticosteroid injections and inflammation on periarticular and generalised bone loss in early rheumatoid arthritis.

  Annals of the rheumatic diseases 20110101

• UDP-glucuronosyltransferase 1A6 overexpression in breast cancer cells resistant to methotrexate.

  Biochemical pharmacology 20110101

• Methylxanthines and inflammatory cells.

  Handbook of experimental pharmacology 20110101

• Improved outcome in 445 patients with Wegener's granulomatosis in a German vasculitis center over four decades.

  Arthritis and rheumatism 20110101

• Pilot study of safety and effect of combined intravitreal bevacizumab and methotrexate for neovascular age-related macular degeneration.

  European journal of ophthalmology 20110101

• Tocilizumab for rheumatoid arthritis: a Cochrane systematic review.

  The Journal of rheumatology 20110101

• The effect of genotype on methotrexate polyglutamate variability in juvenile idiopathic arthritis and association with drug response.

  Arthritis and rheumatism 20110101

• Pericarditis induced by prophylactic administration of isoniazid in a patient with rheumatoid arthritis.

  Joint, bone, spine : revue du rhumatisme 20110101

• Reversion of resistance to immunosuppressive agents in three patients with psoriatic arthritis by cyclosporine A: modulation of P-glycoprotein function.

  Clinical immunology (Orlando, Fla.) 20110101

• Methotrexate-induced subacute neurotoxicity in a child with acute lymphoblastic leukemia carrying genetic polymorphisms related to folate homeostasis.

  American journal of hematology 20110101

• Feasibility of tacrolimus, methotrexate, and prednisolone as a graft-versus-host disease prophylaxis in non-T-cell-depleted haploidentical hematopoietic stem cell transplantation for children.

  Clinical transplantation 20110101

• Rituximab in combination with CODOX-M/IVAC: a retrospective analysis of 23 cases of non-HIV related B-cell non-Hodgkin lymphoma with proliferation index >95%.

  British journal of haematology 20110101

• Synthesis and antiproliferative activity of novel symmetrical alkylthio- and alkylseleno-imidocarbamates.

  European journal of medicinal chemistry 20110101

• Outcome of treatment of adult acute lymphoblastic leukemia with hyperfractionated cyclophosphamide, doxorubicin, vincristine, dexamethasone/methotrexate, cytarabine: results from an Australian population.

  Leukemia & lymphoma 20110101

• Juvenile dermatomyositis: a case study.

  Journal of pediatric health care : official publication of National Association of Pediatric Nurse Associates & Practitioners 20110101

• [Sensorineural hearing loss evolution in Vogt-Koyanagi-Harada syndrome].

  Acta otorrinolaringologica espanola 20110101

• Pharmacogenetics of psoriasis.

  Pharmacogenomics 20110101

• Methotrexate-induced periorbital radiation recall.

  The Annals of pharmacotherapy 20110101

• [Risk factors and subjective symptoms of drug-induced leucopenia].

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20110101

• Effect of methotrexate and leucovorin on female reproductive tract of albino rats.

  Cell biochemistry and function 20110101

• [50-year-old patient with intermittent fever and liver failure].

  Deutsche medizinische Wochenschrift (1946) 20110101

• Blood lipid profiles and peripheral blood mononuclear cell cholesterol metabolism gene expression in patients with and without methotrexate treatment.

  BMC medicine 20110101

• Multicentric reticulohistiocytosis with dermatomyositis-like features: a more common disease presentation than previously thought.

  Dermatology (Basel, Switzerland) 20110101

• The clinical spectrum and therapeutic challenge of eczema herpeticum.

  Pediatric dermatology 20110101

• MTHFR polymorphisms, C677T and A1298C, are not a genetic risk factor for liver stiffness index in methotrexate-treated rheumatoid arthritis patients.

  Clinical and experimental rheumatology 20110101

• Metastatic placental site trophoblastic tumour successfully treated with hysterectomy and EMA/CO chemotherapy.

  Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 20110101

• Characterisation of transient benign hCG elevations in women following chemotherapy for GTT.

  Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 20110101

• Tumor necrosis factor-alpha promotes survival in methotrexate-exposed macrophages by an NF-kappaB-dependent pathway.

  Arthritis research & therapy 20110101

• Abatacept in the treatment of polyarticular JIA: development, clinical utility, and place in therapy.

  Drug design, development and therapy 20110101

• Effects of naproxen and sulphasalazine or methotrexate on hypothalamic-pituitary-adrenal axis activity in patients with rheumatoid arthritis.

  Clinical and experimental rheumatology 20110101

• Selectively weakened binding of methotrexate by human dihydrofolate reductase allows rapid ex vivo selection of mammalian cells.

  Journal of molecular recognition : JMR 20110101

• Old drugs, new uses.

  Pediatric dentistry 20110101

• A phase I trial to evaluate the safety and pharmacokinetics of low-dose methotrexate as an anti-malarial drug in Kenyan adult healthy volunteers.

  Malaria journal 20110101

• [B-cell lymphoma with concurrent myc/IgH and bcl-2/IgH translocations: report of a case].

  Zhonghua bing li xue za zhi = Chinese journal of pathology 20110101

• [Analysis of prophylactic chemotherapy outcome and clinical characteristics in patients of high-risk hydatidiform mole].

  Zhonghua fu chan ke za zhi 20110101

• Management of bullous pemphigoid with topical steroids in the clinical practice of a single center: outcome at 6 and 12 months.

  Dermatology (Basel, Switzerland) 20110101

• [Clostridium difficile-associated diarrhea: causes and relationship to reactive arthritis].

  Harefuah 20110101

• Efficacy of anti-interleukin-1 receptor antagonist anakinra (Kineret®) in a case of refractory Sweet's syndrome.

  Dermatology (Basel, Switzerland) 20110101

• Pharmacogenomics of serious adverse drug reactions in pediatric oncology.

  Journal of population therapeutics and clinical pharmacology = Journal de la therapeutique des populations et de la pharamcologie clinique 20110101

• Uremic toxins inhibit transport by breast cancer resistance protein and multidrug resistance protein 4 at clinically relevant concentrations.

  PloS one 20110101

• Efficacy and safety of leflunomide or methotrexate plus subcutaneous tumour necrosis factor-alpha blocking agents in rheumatoid arthritis.

  International journal of immunopathology and pharmacology 20110101

• The relation between cartilage biomarkers (C2C, C1,2C, CS846, and CPII) and the long-term outcome of rheumatoid arthritis patients within the CAMERA trial.

  Arthritis research & therapy 20110101

• Methotrexate toxicity in growing long bones of young rats: a model for studying cancer chemotherapy-induced bone growth defects in children.

  Journal of biomedicine & biotechnology 20110101

• Chemically induced self-assembly of enzyme nanorings.

  Methods in molecular biology (Clifton, N.J.) 20110101

• Haemophagocytic lymphohistiocytosis: a case series from Mumbai.

  Annals of tropical paediatrics 20110101

• Systemic therapy of atopic dermatitis in children and adults.

  Current problems in dermatology 20110101

• Liver toxicity is rare in rheumatoid arthritis patients using combination therapy with leflunomide and methotrexate.

  Revista brasileira de reumatologia 20110101

• Intravitreal injection of methotrexate in an experimental rabbit model: determination of pharmacokinetics.

  Indian journal of ophthalmology 20110101

• Suspicion of drug-drug interaction between high-dose methotrexate and proton pump inhibitors: a case report - should the practice be changed?

  Chemotherapy 20110101

• [(99m)Tc-MIBI SPECT in the study of brain lymphoma].

  Revista espanola de medicina nuclear 20110101

• Structural correlates of taste and smell loss in encephalitis disseminata.

  PloS one 20110101

• MDM2 antagonist Nutlin-3a potentiates antitumour activity of cytotoxic drugs in sarcoma cell lines.

  BMC cancer 20110101

• Understanding emerging treatment paradigms in rheumatoid arthritis.

  Arthritis research & therapy 20110101

• A highly therapy-resistant case of B-cell lymphoma, unclassifiable, with features intermediate between diffuse large B-cell lymphoma and Burkitt lymphoma showing strong BCL2 staining, otherwise indistinguishable from Burkitt lymphoma.

  Journal of clinical and experimental hematopathology : JCEH 20110101

• Anti-citrullinated peptide antibodies and the progression of radiographic joint erosions in patients with early rheumatoid arthritis treated with FIN-RACo combination and single disease-modifying antirheumatic drug strategies.

  Clinical and experimental rheumatology 20110101

• Investigation of the association between metabolic syndrome and disease activity in rheumatoid arthritis.

  TheScientificWorldJournal 20110101

• Baseline characteristics and patient reported outcome data of patients prescribed etanercept: web-based and telephone evaluation.

  BMC medical research methodology 20110101

• Targeting glutathione-S transferase enzymes in musculoskeletal sarcomas: a promising therapeutic strategy.

  Analytical cellular pathology (Amsterdam) 20110101

• Familial juvenile generalized pustular psoriasis: response to methotrexate.

  Skinmed 20110101

• Management of high-risk gestational trophoblastic neoplasia with etoposide, methotrexate, actinomycin D, cyclophosphamide, vincristine chemotherapy.

  The Journal of reproductive medicine 20110101

• Efficacy and long-term follow-up of IL-1R inhibitor anakinra in adults with Still's disease: a case-series study.

  Arthritis research & therapy 20110101

• Inhibitory effect of caffeic acid on human organic anion transporters hOAT1 and hOAT3: a novel candidate for food-drug interaction.

  Drug metabolism and pharmacokinetics 20110101

• Isolated central nervous system relapse of systemic lymphoma (SCNSL): clinical features and outcome of a retrospective analysis.

  German medical science : GMS e-journal 20110101

• [Efficacy and safety of combination therapy with mizoribine and methotrexate for rheumatoid arthritis resistant with methotrexate].

  Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology 20110101

• Efficacy and safety of the human anti-IL-1β monoclonal antibody canakinumab in rheumatoid arthritis: results of a 12-week, Phase II, dose-finding study.

  BMC musculoskeletal disorders 20110101

• Systemic therapy of psoriasis: methotrexate.

  Bratislavske lekarske listy 20110101

• Design, modeling, expression, and chemoselective PEGylation of a new nanosize cysteine analog of erythropoietin.

  International journal of nanomedicine 20110101

• Risk of hepatotoxicity with add-on leflunomide in rheumatoid arthritis patients.

  Arzneimittel-Forschung 20110101

• [Methotrexate-induced changes in the concentration of antibodies to mutaded citrullinated vimentin in blood serum of patients with rheumatoid arthritis].

  Terapevticheskii arkhiv 20110101

• Protective role of taurine against genotoxic damage in mice treated with methotrexate and tamoxfine.

  Environmental toxicology and pharmacology 20110101

• Concurrent versus sequential administration of CMF chemotherapy and radiotherapy after breast-conserving surgery in early breast cancer.

  Tumori 20110101

• Optical coherence tomography: a new tool to assess nail disease in psoriasis?

  Dermatology (Basel, Switzerland) 20110101

• [Consensus Statement of the Spanish Society of Rheumatology on the management of biologic therapies in spondyloarthritis except for psoriatic arthritis].

  Reumatologia clinica 20110101

• [Reactivation of hepatitis B in a patient with spondyloarthritis after the suspension of methotrexate and efficacy of treatment with antivirals in association to adalimumab].

  Reumatologia clinica 20110101

• [How does one manage patients with rheumatoid arthritis and positive serology to hepatitis B, hepatitis C, human immunodeficiency virus?].

  Reumatologia clinica 20110101

• A single-blinded trial of methotrexate versus azathioprine as steroid-sparing agents in generalized myasthenia gravis.

  BMC neurology 20110101

• Effects of methotrexate on vascular endothelial growth factor, angiopoietin 1, and angiopoietin 2 in nasal polyps.

  American journal of rhinology & allergy 20110101

• [Methotrexate to treat SAPHO syndrome with keloidal scars].

  Acta reumatologica portuguesa 20110101

• Enhanced anti-tumoral activity of methotrexate-human serum albumin conjugated nanoparticles by targeting with Luteinizing Hormone-Releasing Hormone (LHRH) peptide.

  International journal of molecular sciences 20110101

• Role of inducible nitric oxide synthase pathway on methotrexate-induced intestinal mucositis in rodents.

  BMC gastroenterology 20110101

• Adalimumab-associated pulmonary cryptococcosis.

  Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia 20110101

• The influence of 7-OH methotrexate metabolite on clinical relevance of methotrexate determination.

  Clinical laboratory 20110101

• [An atypical presentation of primary cutaneous diffuse B-cell lymphoma, leg type].

  Annales de dermatologie et de venereologie 20110101

• [An extremely high serum methotrexate concentration associated with acute renal failure in a patient with acute lymphoblastic leukemia after conduction of high dose consolidation].

  Terapevticheskii arkhiv 20110101

• Convection-enhanced delivery of methotrexate-loaded maghemite nanoparticles.

  International journal of nanomedicine 20110101

• Antiepileptic drugs reduce the efficacy of methotrexate chemotherapy through accelerated degradation of the reduced folate carrier by the ubiquitin-proteasome pathway.

  Chemotherapy 20110101

• [Prevention of posterior capsule opacification in experimental studies].

  Klinika oczna 20110101

• Use of biotin targeted methotrexate-human serum albumin conjugated nanoparticles to enhance methotrexate antitumor efficacy.

  International journal of nanomedicine 20110101

• Widespread scleredema associated with paraproteinemia and generalized osteoarthritis in an HLA-B39 positive patient.

  Acta dermatovenerologica Croatica : ADC 20110101

• Residents' corner September 2011. sQUIZ your knowledge!

  European journal of dermatology : EJD 20110101

• Clinical characteristics and prognosis of osteosarcoma in young children: a retrospective series of 15 cases.

  BMC cancer 20110101

• Interstitial lung disease in rheumatoid arthritis: response to IL-6R blockade.

  Scandinavian journal of rheumatology 20110101

• [Acute toxicity by methotrexate used for abortion purpose. Case report].

  Ginecologia y obstetricia de Mexico 20110101

• Improved retroviral suicide gene transfer in colon cancer cell lines after cell synchronization with methotrexate.

  Journal of experimental & clinical cancer research : CR 20110101

• Mucositis after reduced intensity conditioning and allogeneic stem cell transplantation.

  Onkologie 20110101

• Use of metronomic chemotherapy in oncology: results from a national Italian survey.

  Tumori 20110101

• The impact of therapy for childhood acute lymphoblastic leukaemia on intelligence quotients; results of the risk-stratified randomized central nervous system treatment trial MRC UKALL XI.

  Journal of hematology & oncology 20110101

• Effect of ABCB1 and ABCC3 polymorphisms on osteosarcoma survival after chemotherapy: a pharmacogenetic study.

  PloS one 20110101

• Early effects of IL-6 receptor inhibition on bone homeostasis: a pilot study in women with rheumatoid arthritis.

  Clinical and experimental rheumatology 20110101

• SAPHO syndrome associated with hidradenitis suppurativa successfully treated with infliximab and methotrexate.

  Bulletin of the NYU hospital for joint diseases 20110101

• Low-dose tacrolimus with methotrexate repairs rheumatoid fingers.

  Internal medicine (Tokyo, Japan) 20110101

• Importance of correlation between gene expression levels: application to the type I interferon signature in rheumatoid arthritis.

  PloS one 20110101

• The impact of uterine re-curettage, pre-evacuation and week-one level of hCG on the number of chemotherapy courses in treatment of post molar GTN.

  Journal of experimental therapeutics & oncology 20110101

• Novel formulation of a methotrexate derivative with a lipid nanoemulsion.

  International journal of nanomedicine 20110101

• A rare bladder cancer--small cell carcinoma: review and update.

  Orphanet journal of rare diseases 20110101

• Psoriasiform disorders with joint symptoms.

  Nederlands tijdschrift voor geneeskunde 20110101

• Treatment outcome of adult Burkitt Lymphoma in Japanese patients with modified LMB protocol : a single center retrospective analysis.

  Journal of clinical and experimental hematopathology : JCEH 20110101

• Unusual presentation of primary gastric choriocarcinoma in a 24-year-old female patient.

  Boletin de la Asociacion Medica de Puerto Rico 20110101

• Profile and course of early rheumatoid arthritis in Morocco: a two-year follow-up study.

  BMC musculoskeletal disorders 20110101

• The influence of methotrexate on the gene expression of the pro-inflammatory cytokine IL-12A in the therapy of rheumatoid arthritis.

  Clinical and experimental rheumatology 20110101

• Nephrotoxicity of anticancer drugs--an underestimated problem?

  Acta clinica Belgica 20110101

• Decreased influenza-specific B cell responses in rheumatoid arthritis patients treated with anti-tumor necrosis factor.

  Arthritis research & therapy 20110101

• Old school regimen may turn the tide in metastatic breast cancer.

  Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20110101

• Effect of additional administration of tacrolimus in patients with rheumatoid arthritis treated with biologics.

  Fukushima journal of medical science 20110101

• Ovarian hyperstimulation syndrome in a spontaneous pregnancy with invasive mole: report of a case.

  The Pan African medical journal 20110101

• Contact dermatitis to parthenium weed treated with methotrexate and triamcinolone acetonide.

  BMJ case reports 20110101

• Accidental methotrexate ingestion in a 19-month-old child.

  BMJ case reports 20110101

• Development of a dot-blot assay for screening monoclonal antibodies to low-molecular-mass drugs.

  Analytical biochemistry 20101215

• Ambulatory high-dose methotrexate administration among pediatric osteosarcoma patients in an urban, underserved setting is feasible, safe, and cost-effective.

  Pediatric blood & cancer 20101215

• Low-dose carboxypeptidase-G2 for methotrexate toxicity in a child.

  Pediatric blood & cancer 20101215

• Phenotypic enhancement of thymidylate synthetase pathway inhibitors following ablation of Neil1 DNA glycosylase/lyase.

  Cell cycle (Georgetown, Tex.) 20101215

• Use of calcium folinate in the management of accidental methotrexate ingestion in two dogs.

  Journal of the American Veterinary Medical Association 20101215

• Effect of mitoxantrone on outcome of children with first relapse of acute lymphoblastic leukaemia (ALL R3): an open-label randomised trial.

  Lancet (London, England) 20101211

• Efficacy and safety of mycophenolate mofetil vs. methotrexate for the treatment of chronic plaque psoriasis.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20101201

• Folylpolyglutamate synthetase gene transcription is regulated by a multiprotein complex that binds the TEL-AML1 fusion in acute lymphoblastic leukemia.

  Leukemia research 20101201

• The clinical outcome of chemotherapy-induced amenorrhea in premenopausal young patients with breast cancer with long-term follow-up.

  Annals of surgical oncology 20101201

• Elevated level of serum cystatin-C concentration is a useful predictor for myelosuppression induced by methotrexate for treatment of rheumatoid arthritis.

  Modern rheumatology 20101201

• Organizing pneumonia in a patient with rheumatoid arthritis treated with etanercept.

  Modern rheumatology 20101201

• Severe and refractory myositis in mixed connective tissue disease: a description of a rare case.

  Lupus 20101201

• A single-center experience with methotrexate after thiopurine therapy in pediatric Crohn disease.

  Journal of pediatric gastroenterology and nutrition 20101201

• Changes in glycosylated hemoglobin after initiation of hydroxychloroquine or methotrexate treatment in diabetes patients with rheumatic diseases.

  Arthritis and rheumatism 20101201

• Sepiapterin reverses the changes in gastric nNOS dimerization and function in diabetic gastroparesis.

  Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20101201

• Assessment of liver fibrosis with transient elastography and FibroTest in patients treated with methotrexate for chronic inflammatory diseases: a case-control study.

  Journal of hepatology 20101201

• Primary cutaneous Epstein-Barr virus-associated B-cell lymphoma arising at the site of subcutaneous injections of methotrexate.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20101201

• Ionic liquid based microemulsion with pharmaceutically accepted components: Formulation and potential applications.

  Journal of colloid and interface science 20101201

• Single high dose treatment with methotrexate causes long-lasting cognitive dysfunction in laboratory rodents.

  Pharmacology, biochemistry, and behavior 20101201

• A predictive ligand-based Bayesian model for human drug-induced liver injury.

  Drug metabolism and disposition: the biological fate of chemicals 20101201

• A rare unilateral case of ocular mucous membrane pemphigoid.

  Cornea 20101201

• The association of common variable immune deficiency with idiopathic inflammatory myopathies.

  Joint, bone, spine : revue du rhumatisme 20101201

• PTPN22 1858C>T polymorphism is strongly associated with rheumatoid arthritis but not with a response to methotrexate therapy.

  International immunopharmacology 20101201

• Preparing the patient for immunosuppressive therapy.

  Current gastroenterology reports 20101201

• Laser modulated transmembrane convection: Implementation in cancer chemotherapy.

  Journal of controlled release : official journal of the Controlled Release Society 20101201

• Investigation of kinetics of methotrexate for therapeutic treatment of intraocular lymphoma.

  Current eye research 20101201

• Dose intensity of chemotherapy in patients with relapsed Hodgkin's lymphoma.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20101201

• The safety and effectiveness of a chloroform/methanol extract of Tripterygium wilfordii Hook F (T2) plus methotrexate in treating rheumatoid arthritis.

  Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20101201

• Unusual association of ankylosing spondylitis with congenital spinal deformity.

  Spine 20101201

• [Imaging findings and differentials in neurosarcoidosis].

  RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin 20101201

• Treatment of advanced extranodal NK/T cell lymphoma, nasal-type and aggressive NK-cell leukemia.

  International journal of hematology 20101201

• Difficulty measuring methotrexate in a patient with high-dose methotrexate-induced nephrotoxicity.

  Clinical chemistry 20101201

• Commentary.

  Clinical chemistry 20101201

• Commentary.

  Clinical chemistry 20101201

• Modified cyclophosphamide, vincristine, doxorubicin, and methotrexate (CODOX-M)/ifosfamide, etoposide, and cytarabine (IVAC) therapy with or without rituximab in Japanese adult patients with Burkitt lymphoma (BL) and B cell lymphoma, unclassifiable, with features intermediate between diffuse large B cell lymphoma and BL.

  International journal of hematology 20101201

• Dose dense cyclophosphamide, methotrexate, fluorouracil is feasible at 14-day intervals: a pilot study of every-14-day dosing as adjuvant therapy for breast cancer.

  Clinical breast cancer 20101201

• Modeling mechanisms of in vivo variability in methotrexate accumulation and folate pathway inhibition in acute lymphoblastic leukemia cells.

  PLoS computational biology 20101201

• Impact of adjuvant chemotherapy on patients with lymph node metastasis at the time of radical cystectomy.

  The Canadian journal of urology 20101201

• Nanogel particulates located within diffusion cell receptor phases following topical application demonstrates uptake into and migration across skin.

  International journal of pharmaceutics 20101130

• Synthesis, characterization, and in vitro evaluation of long-chain hyperbranched poly(ethylene glycol) as drug carrier.

  Bioconjugate chemistry 20101117

• Arsenic trioxide improves event-free and overall survival for adults with acute promyelocytic leukemia: North American Leukemia Intergroup Study C9710.

  Blood 20101111

• Immunomodulatory treatment other than corticosteroids, immunoglobulin and plasma exchange for chronic inflammatory demyelinating polyradiculoneuropathy.

  The Cochrane database of systematic reviews 20101110

• Cytokine-dependent but acquired immunity-independent arthritis caused by DNA escaped from degradation.

  Proceedings of the National Academy of Sciences of the United States of America 20101109

• Synthesis of non-cytotoxic poly(ester-amine) dendrimers as potential solubility enhancers for drugs: methotrexate as a case study.

  Molecules (Basel, Switzerland) 20101109

• Zonula Occludens-1 alterations and enhanced intestinal permeability in methotrexate-treated rats.

  Cancer chemotherapy and pharmacology 20101101

• Hyper-alkalinization without hyper-hydration for the prevention of high-dose methotrexate acute nephrotoxicity in patients with osteosarcoma.

  Cancer chemotherapy and pharmacology 20101101

• Manganese superoxide dismutase polymorphism, treatment-related toxicity and disease-free survival in SWOG 8897 clinical trial for breast cancer.

  Breast cancer research and treatment 20101101

• Survival of breast cancer patients with meningeal carcinomatosis.

  Annals of oncology : official journal of the European Society for Medical Oncology 20101101

• Changes in the expression of pituitary adenylate cyclase-activating polypeptide in the human placenta during pregnancy and its effects on the survival of JAR choriocarcinoma cells.

  Journal of molecular neuroscience : MN 20101101

• Guillain-Barré syndrome mimicking acute methotrexate-associated encephalopathy in an adolescent patient with lymphoblastic lymphoma.

  Journal of pediatric hematology/oncology 20101101

• Adenosine 5'-triphosphate infusions reduced disease activity and inflammation in a patient with active rheumatoid arthritis.

  Rheumatology (Oxford, England) 20101101

• Methotrexate in patients with primary biliary cirrhosis who respond incompletely to treatment with ursodeoxycholic acid.

  Digestive diseases and sciences 20101101

• More evidence of declining incidence of amyloidosis associated with inflammatory rheumatic diseases.

  Scandinavian journal of rheumatology 20101101

• Successful treatment of disseminated granuloma annulare with methotrexate.

  The British journal of dermatology 20101101

• Preclinical and clinical investigation of a CCR5 antagonist, AZD5672, in patients with rheumatoid arthritis receiving methotrexate.

  Arthritis and rheumatism 20101101

• ABCC11/MRP8 confers pemetrexed resistance in lung cancer.

  Cancer science 20101101

• A case of progressive multifocal leukoencephalopathy in a patient treated with infliximab.

  Arthritis and rheumatism 20101101

• Beneficial effects of cathepsin inhibition to prevent chemotherapy-induced intestinal mucositis.

  Clinical and experimental immunology 20101101

• SLC19A1 pharmacogenomics summary.

  Pharmacogenetics and genomics 20101101

• Generation of novel pharmacogenomic candidates in response to methotrexate in juvenile idiopathic arthritis: correlation between gene expression and genotype.

  Pharmacogenetics and genomics 20101101

• [Idiopathic hypertrophic pachymeningitis].

  RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin 20101101

• Synthesis and biological evaluation of 2-phenylthiazole-4-carboxamide derivatives as anticancer agents.

  European journal of medicinal chemistry 20101101

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• Methotrexate for primary biliary cirrhosis: who is to be trusted?

  Digestive diseases and sciences 20101101

• A nonradiation-containing, intermediate-dose methotrexate regimen for elderly patients with primary central nervous system lymphoma.

  International journal of hematology 20101101

• How important is whole brain radiotherapy for treatment of primary CNS lymphoma?

  The Lancet. Oncology 20101101

• High-dose methotrexate with or without whole brain radiotherapy for primary CNS lymphoma (G-PCNSL-SG-1): a phase 3, randomised, non-inferiority trial.

  The Lancet. Oncology 20101101

• Tocilizumab for the treatment of rheumatoid arthritis.

  Expert review of clinical immunology 20101101

• How genetic variation affects patient response and outcome to therapy for psoriasis.

  Expert review of clinical immunology 20101101

• Primary malignant bone neoplasm: a case report of dedifferentiated chondrosarcoma in the rib and review of the literature.

  Chinese journal of cancer 20101101

• Serum hCG level and rising world health organization score at second-line chemotherapy (pulse dactinomycin): poor prognostic factors for methotrexate-failed low-risk gestational trophoblastic neoplasia.

  International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20101101

• Sudden onset of an aggressive cutaneous lymphoma in a young patient with psoriasis: role of immunosuppressants.

  Acta dermato-venereologica 20101101

• Facial basal cell carcinoma in a young patient with Crohn disease.

  The Journal of craniofacial surgery 20101101

• Kaposi's sarcoma: an opportunistic infection by human herpesvirus-8 in ulcerative colitis.

  Journal of Crohn's & colitis 20101101

• Nephrotoxicity from chemotherapeutic agents: clinical manifestations, pathobiology, and prevention/therapy.

  Seminars in nephrology 20101101

• [Clinical analysis of patients with relapsed and chemo-resistant gestational trophoblastic neoplasia].

  Zhonghua fu chan ke za zhi 20101101

• Effect of proanthocyanidin, arginine and glutamine supplementation on methotrexate-induced gastrointestinal toxicity in rats.

  Methods and findings in experimental and clinical pharmacology 20101101

• [A successful case of tanshinone II A treatment for relapsed acute promyelocytic leukemia after maintainance therapy of all-trans retinoic acid and arsenic trioxide].

  Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20101101

• [Effect of Bizhongxiao decoction on proteomics of peripheral blood mononuclear cells in patients with rheumatoid arthritis].

  Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20101101

• A case report of limited Wegener's granulomatosis presenting with a chronic scalp ulcer.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20101101

• Cola beverage and delayed elimination of methotrexate.

  British journal of clinical pharmacology 20101101

• Peripheral ulcerative keratitis in a patient with systemic-onset juvenile idiopathic arthritis.

  Journal of pediatric ophthalmology and strabismus 20101021

• Nimesulide improves the disease modifying anti-rheumatic profile of methotrexate in mice with collagen-induced arthritis.

  European journal of pharmacology 20101010

• Quantitative experimental assessment of macromolecular crowding effects at membrane surfaces.

  Biophysical journal 20101006

• Antiproliferative effects of anastrozole, methotrexate, and 5-fluorouracil on endometriosis in vitro and in vivo.

  Fertility and sterility 20101001

• Effects of long-term disease-modifying antirheumatic drugs on endothelial function in patients with early rheumatoid arthritis.

  Cardiovascular therapeutics 20101001

• Combining etanercept with traditional agents in the treatment of psoriasis: a review of the clinical evidence.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20101001

• CD8(+) T-cell lymphoproliferative disorder associated with Epstein-Barr virus in a patient with rheumatoid arthritis during methotrexate therapy.

  Modern rheumatology 20101001

• Radiographic progression and remission rates in early rheumatoid arthritis - MRI bone oedema and anti-CCP predicted radiographic progression in the 5-year extension of the double-blind randomised CIMESTRA trial.

  Annals of the rheumatic diseases 20101001

• Evaluation of multi-organ DNA damage by comet assay from 28 days repeated dose oral toxicity test in mice: a practical approach for test integration in regulatory toxicity testing.

  Regulatory toxicology and pharmacology : RTP 20101001

• Are switches from oral to subcutaneous methotrexate or addition of ciclosporin to methotrexate useful steps in a tight control treatment strategy for rheumatoid arthritis? A post hoc analysis of the CAMERA study.

  Annals of the rheumatic diseases 20101001

• Efficacy and safety of tacrolimus in 101 consecutive patients with rheumatoid arthritis.

  Modern rheumatology 20101001

• Anthracycline dose intensification in adult acute lymphoblastic leukemia: lack of benefit in the context of the fractionated cyclophosphamide, vincristine, doxorubicin, and dexamethasone regimen.

  Cancer 20101001

• Chemotherapy and interferon-alpha treatment of Erdheim-Chester disease.

  Pediatric blood & cancer 20101001

• 677TT genotype is associated with elevated risk of methotrexate (MTX) toxicity in juvenile idiopathic arthritis: treatment outcome, erythrocyte concentrations of MTX and folates, and MTHFR polymorphisms.

  The Journal of rheumatology 20101001

• Enhanced topical delivery and anti-inflammatory activity of methotrexate from an activated nanogel.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20101001

• Intralesional chemotherapy for nonmelanoma skin cancer: a practical review.

  Journal of the American Academy of Dermatology 20101001

• Diagnostic multimodal imaging and therapeutic transcatheter arterial chemoembolization for conservative management of hemorrhagic cesarean scar pregnancy.

  European journal of obstetrics, gynecology, and reproductive biology 20101001

• Combination intravitreal rituximab and methotrexate for massive subretinal lymphoma.

  Eye (London, England) 20101001

• Renal cell carcinoma and acute promyelocytic leukemia: a nonrandom association?

  American journal of hematology 20101001

• Salvage chemotherapy with methotrexate, etoposide and actinomycin D in men with metastatic nonseminomatous germ cell tumors with a choriocarcinoma component: a preliminary report.

  International journal of urology : official journal of the Japanese Urological Association 20101001

• Phase I trial of bortezomib in combination with rituximab-HyperCVAD alternating with rituximab, methotrexate and cytarabine for untreated aggressive mantle cell lymphoma.

  British journal of haematology 20101001

• [Bullous pemphigoid].

  Presse medicale (Paris, France : 1983) 20101001

• [Linear localized scleroderma. Successful treatment with prednisolone pulse therapy and methotrexate].

  Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20101001

• Incidence and risk factors of venous thromboembolic events in lymphoma.

  The American journal of medicine 20101001

• Induction of pulmonary fibrosis by methotrexate treatment in mice lung in vivo and in vitro.

  The Journal of toxicological sciences 20101001

• Treatment of morphea or localized scleroderma: review of the literature.

  Journal of drugs in dermatology : JDD 20101001

• [Bufalin induces apoptosis in osteosarcoma U-2OS and U-2OS methotrexate 300-resistant cell lines in vitro].

  Zhonghua zhong liu za zhi [Chinese journal of oncology] 20101001

• High-dose methotrexate during pregnancy: risk of malformations.

  Prescrire international 20101001

• Methotrexate during the first trimester of pregnancy.

  Prescrire international 20101001

• Dihydrofolate reductase transcript level is not suitable for methotrexate-resistance prediction in choriocarcinoma cell line.

  International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20101001

• An oral spleen tyrosine kinase (Syk) inhibitor for rheumatoid arthritis.

  The New England journal of medicine 20100930

• Intravenous methotrexate as central nervous system (CNS) prophylaxis is associated with a low risk of CNS recurrence in high-risk patients with diffuse large B-cell lymphoma.

  Cancer 20100915

• Molecular structure, vibrational spectra and DFT molecular orbital calculations (TD-DFT and NMR) of the antiproliferative drug Methotrexate.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20100915

• Management of severe asthma in children.

  Lancet (London, England) 20100904

• Compliance with methotrexate treatment in patients with rheumatoid arthritis: influence of patients' beliefs about the medicine. A prospective cohort study.

  Rheumatology international 20100901

• The impact of high-dose methotrexate on intracellular 6-mercaptopurine disposition during interval therapy of childhood acute lymphoblastic leukemia.

  Cancer chemotherapy and pharmacology 20100901

• Randomized controlled phase II comparison study of concurrent chemoradiotherapy with docetaxel, cisplatin, and 5-fluorouracil versus CCRT with cisplatin, 5-fluorouracil, methotrexate and leucovorin in patients with locally advanced squamous cell carcinoma of the head and neck.

  Cancer chemotherapy and pharmacology 20100901

• Etoposide induces more severe mucositis than CY when added to TBI as conditioning in allograft recipients receiving CsA and MTX.

  Bone marrow transplantation 20100901

• A proof-of-concept and drug-drug interaction study of pamapimod, a novel p38 MAP kinase inhibitor, with methotrexate in patients with rheumatoid arthritis.

  Journal of clinical pharmacology 20100901

• MTX or mycophenolate mofetil with CsA as GVHD prophylaxis after reduced-intensity conditioning PBSCT from HLA-identical siblings.

  Bone marrow transplantation 20100901

• Probing the structure of Leishmania donovani chagasi DHFR-TS: comparative protein modeling and protein-ligand interaction studies.

  Journal of molecular modeling 20100901

• Therapeutic efficacy of experimental rheumatoid arthritis with low-dose methotrexate by increasing partially CD4+CD25+ Treg cells and inducing Th1 to Th2 shift in both cells and cytokines.

  Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20100901

• Maternal exposure to leflunomide and methotrexate in a patient with adult-onset Still's disease.

  Rheumatology (Oxford, England) 20100901

• Cyclosporin and methotrexate therapy induces remission in type 1 diabetes mellitus.

  Acta diabetologica 20100901

• Risk of elevated liver enzymes associated with TNF inhibitor utilisation in patients with rheumatoid arthritis.

  Annals of the rheumatic diseases 20100901

• Sicca symptoms, and lacrimal and salivary flow in Albanian patients with rheumatoid arthritis.

  Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20100901

• Efficacy and safety of different doses and retreatment of rituximab: a randomised, placebo-controlled trial in patients who are biological naive with active rheumatoid arthritis and an inadequate response to methotrexate (Study Evaluating Rituximab's Efficacy in MTX iNadequate rEsponders (SERENE)).

  Annals of the rheumatic diseases 20100901

• Anaphylactoid reaction to high-dose methotrexate and successful desensitization.

  Pediatric blood & cancer 20100901

• Persistent pruritic papules and plaques: a characteristic histopathologic presentation seen in a subset of patients with adult-onset and juvenile Still's disease.

  Journal of cutaneous pathology 20100901

• Comparison between adalimumab, etanercept, and infliximab in rheumatoid arthritis: comment on the article by Hetland et al.

  Arthritis and rheumatism 20100901

• Treatment approaches to juvenile dermatomyositis (JDM) across North America: The Childhood Arthritis and Rheumatology Research Alliance (CARRA) JDM Treatment Survey.

  The Journal of rheumatology 20100901

• Sensitivity and resistance towards isoliquiritigenin, doxorubicin and methotrexate in T cell acute lymphoblastic leukaemia cell lines by pharmacogenomics.

  Naunyn-Schmiedeberg's archives of pharmacology 20100901

• Development of methotrexate proline prodrug to overcome resistance by MDA-MB-231 cells.

  Bioorganic & medicinal chemistry letters 20100901

• Glucarpidase, leucovorin, and thymidine for high-dose methotrexate-induced renal dysfunction: clinical and pharmacologic factors affecting outcome.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100901

• Outcome and toxicity associated with a dose-intensified, maintenance-free CHOP-based chemotherapy protocol in canine lymphoma: 130 cases.

  Veterinary and comparative oncology 20100901

• Cancer stem-like cells can be isolated with drug selection in human ovarian cancer cell line SKOV3.

  Acta biochimica et biophysica Sinica 20100901

• Neoadjuvant treatment in young women with breast cancer.

  Breast cancer research and treatment 20100901

• Adjuvant chemotherapy in young women with breast cancer.

  Breast cancer research and treatment 20100901

• The morbidly adherent placenta: an overview of management options.

  Acta obstetricia et gynecologica Scandinavica 20100901

• Comparison of two high-dose cyclophosphamide, doxorubicin, vincristine, and prednisone derived regimens in patients aged under 60 years with low-intermediate risk aggressive lymphoma: a final analysis of the multicenter LNH93-2 protocol.

  Leukemia & lymphoma 20100901

• [Arthritis of the atlanto-axial joint with inflammatory neck pain as a primary manifestation of seronegative rheumatoid arthritis].

  Deutsche medizinische Wochenschrift (1946) 20100901

• Cardio-ankle vascular index for evaluating immunosuppressive therapy in a patient with aortitis syndrome.

  The Tohoku journal of experimental medicine 20100901

• [Guidelines on the use of methotrexate in psoriasis].

  Actas dermo-sifiliograficas 20100901

• Delayed elimination of methotrexate associated with co-administration of proton pump inhibitors.

  Anticancer research 20100901

• [Temporal arteritis: treatment controversies].

  Neurologia (Barcelona, Spain) 20100901

• [Molecular subtypes and individualized treatment of breast cancer].

  Zhonghua zhong liu za zhi [Chinese journal of oncology] 20100901

• Drug interaction between celecoxib and methotrexate in organic anion transporter 3-transfected renal cells and in rats in vivo.

  European journal of pharmacology 20100825

• CNS relapse in acute promyeloctyic leukemia.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100820

• P2X(7) receptor-mediated release of cathepsins from macrophages is a cytokine-independent mechanism potentially involved in joint diseases.

  Journal of immunology (Baltimore, Md. : 1950) 20100815

• Organic anion transporting polypeptide 1a/1b-knockout mice provide insights into hepatic handling of bilirubin, bile acids, and drugs.

  The Journal of clinical investigation 20100802

• Gynecomastia associated with low-dose methotrexate therapy for rheumatoid arthritis ameliorated by folate supplement.

  Rheumatology international 20100801

• Two cases of distal extremity swelling with pitting oedema in psoriatic arthritis: the different pathological mechanisms.

  Rheumatology international 20100801

• In silico structure-based design of a novel class of potent and selective small peptide inhibitor of Mycobacterium tuberculosis Dihydrofolate reductase, a potential target for anti-TB drug discovery.

  Molecular diversity 20100801

• Lack of association between elevated mean red cell volume and haematological toxicity in patients receiving long-term methotrexate for rheumatoid arthritis.

  Internal medicine journal 20100801

• DNA incorporation of 6-thioguanine nucleotides during maintenance therapy of childhood acute lymphoblastic leukaemia and non-Hodgkin lymphoma.

  Cancer chemotherapy and pharmacology 20100801

• Ocular manifestations in a community-based cohort of patients with inflammatory bowel disease.

  Inflammatory bowel diseases 20100801

• Should patients under long-term anti-TNF therapies be followed for tuberculosis contamination?

  Inflammatory bowel diseases 20100801

• A probable case of transfusion-transmitted hepatitis B virus infection in an immunosuppressed recipient caused by an occult HBV-infected donor with negative ID-NAT.

  Transfusion medicine (Oxford, England) 20100801

• Pyridoxine treatment of vincristine-induced cranial polyneuropathy in an adult patient with acute lymphocytic leukemia: Case report and review of the literature.

  Leukemia research 20100801

• Efficacy of methotrexate in ulcerative colitis: failure or promise.

  Inflammatory bowel diseases 20100801

• Predictors for remission in rheumatoid arthritis patients: A systematic review.

  Arthritis care & research 20100801

• Primary cytomegalovirus infection with accompanying Pneumocystis jiroveci pneumonia in a patient with large-vessel vasculitis.

  Infection 20100801

• Endoscopic diagnosis of childhood Burkitt's lymphoma of the colon.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100801

• In vitro-in vivo correlation for intrinsic clearance for drugs metabolized by human aldehyde oxidase.

  Drug metabolism and disposition: the biological fate of chemicals 20100801

• CEF is superior to CMF for tumours with TOP2A aberrations: a Subpopulation Treatment Effect Pattern Plot (STEPP) analysis on Danish Breast Cancer Cooperative Group Study 89D.

  Breast cancer research and treatment 20100801

• Allogeneic hematopoietic stem cell transplant following chemotherapy containing l-asparaginase as a promising treatment for patients with relapsed or refractory extranodal natural killer/T cell lymphoma, nasal type.

  Leukemia & lymphoma 20100801

• Beneficial effect of erdosteine on methotrexate-induced testicular toxicity in mice.

  Toxicology and industrial health 20100801

• Moyamoya in a child treated with interferon for recurrent osteosarcoma.

  Journal of pediatric hematology/oncology 20100801

• Effect of oral itraconazole on the pharmacokinetics of tacrolimus in a hematopoietic stem cell transplant recipient with CYP3A5*3/*3.

  American journal of hematology 20100801

• Secondary adrenal insufficiency in an infant after intrathecal triple chemotherapy.

  Pediatric blood & cancer 20100801

• Randomized trial to compare LSA2L2-type maintenance therapy to daily 6-mercaptopurine and weekly methotrexate with vincristine and dexamethasone pulse for children with acute lymphoblastic leukemia.

  Pediatric blood & cancer 20100801

• A breast cancer prognostic signature predicts clinical outcomes in multiple tumor types.

  Oncology reports 20100801

• Langerhans cell histiocytosis in a child with non-Hodgkin lymphoma.

  Journal of pediatric hematology/oncology 20100801

• [Methotrexate in the therapy of juvenile idiopathic arthritis].

  Zeitschrift fur Rheumatologie 20100801

• [Hemiparesis in acute lymphoblastic leukemia].

  Der Radiologe 20100801

• Complete paraplegia after nelarabine treatment in a T-cell acute lymphoblastic leukemia adult patient.

  American journal of hematology 20100801

• Testicular lymphoma, intraocular (vitreoretinal) lymphoma, and brain lymphoma: involvement of three immunoprivileged sites in one patient.

  American journal of hematology 20100801

• MDR1 and ERCC1 expression predict outcome of patients with locally advanced bladder cancer receiving adjuvant chemotherapy.

  Neoplasia (New York, N.Y.) 20100801

• Flows and flaws in primary central nervous system lymphoma.

  Nature reviews. Clinical oncology 20100801

• Rituximab in intractable ocular lesions of Behcet's disease; randomized single-blind control study (pilot study).

  International journal of rheumatic diseases 20100801

• Lipoatrophic panniculitis: case report and review of the literature.

  Archives of dermatology 20100801

• Inhibition of JAK kinases in patients with rheumatoid arthritis: scientific rationale and clinical outcomes.

  Best practice & research. Clinical rheumatology 20100801

• A rapidly growing lymphoma and tumor lysis syndrome in a toddler.

  JAAPA : official journal of the American Academy of Physician Assistants 20100801

• Assessment of the role of renal organic anion transporters in drug-induced nephrotoxicity.

  Toxins 20100801

• Enteric-coated mycophenolate sodium versus mycophenolate mofetil maintenance immunosuppression: outcomes analysis of the United Network for Organ Sharing/Organ Procurement and Transplantation Network database.

  Transplantation 20100715

• Pteridine-sulfonamide conjugates as dual inhibitors of carbonic anhydrases and dihydrofolate reductase with potential antitumor activity.

  Bioorganic & medicinal chemistry 20100715

• Evaluation of posttransplant methotrexate to facilitate engraftment in the canine major histocompatibility complex-haploidentical nonmyeloablative transplant model.

  Transplantation 20100715

• The effect of anti-TNF treatment on the immunogenicity and safety of the 7-valent conjugate pneumococcal vaccine in children with juvenile idiopathic arthritis.

  Vaccine 20100712

• Tocilizumab for rheumatoid arthritis.

  The Cochrane database of systematic reviews 20100707

• Randomized trial of cyclophosphamide, epirubicin, and fluorouracil chemotherapy compared with cyclophosphamide, methotrexate, and fluorouracil with node-positive breast cancer in Japan.

  Breast cancer (Tokyo, Japan) 20100701

• Methotrexate for maintenance of remission in chronic active Crohn's disease: long-term single-center experience and meta-analysis of observational studies.

  Inflammatory bowel diseases 20100701

• Monotherapy with methotrexate for primary central nervous lymphoma has single agent activity in the absence of radiotherapy: a single institution cohort.

  Journal of neuro-oncology 20100701

• Bevacizumab in metastatic breast cancer: a meta-analysis of randomized controlled trials.

  Breast cancer research and treatment 20100701

• A randomized phase II trial comparing tacrolimus and mycophenolate mofetil to tacrolimus and methotrexate for acute graft-versus-host disease prophylaxis.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20100701

• Lenalidomide and dexamethasone for the treatment of refractory/relapsed multiple myeloma: dosing of lenalidomide according to renal function and effect on renal impairment.

  European journal of haematology 20100701

• Safety and immunogenicity of varicella vaccine in patients with juvenile rheumatic diseases receiving methotrexate and corticosteroids.

  Arthritis care & research 20100701

• Sequelae of osteosarcoma medical therapy: a review of rare acute toxicities and late effects.

  The Lancet. Oncology 20100701

• Characterisation of the bifunctional dihydrofolate synthase-folylpolyglutamate synthase from Plasmodium falciparum; a potential novel target for antimalarial antifolate inhibition.

  Molecular and biochemical parasitology 20100701

• Bioanalytical method development for a generation 5 polyamidoamine folic acid methotrexate conjugated nanoparticle.

  Analytical and bioanalytical chemistry 20100701

• Methotrexate drug interactions in the treatment of rheumatoid arthritis: a systematic review.

  The Journal of rheumatology 20100701

• Dioxin mediates downregulation of the reduced folate carrier transport activity via the arylhydrocarbon receptor signalling pathway.

  Toxicology and applied pharmacology 20100701

• Protective effect of lipoic acid against methotrexate-induced oxidative stress in liver mitochondria.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100701

• Effects of in vitro exposure of Echinococcus multilocularis metacestodes to cytostatic drugs on in vivo growth and proliferation of the parasite.

  Parasitology research 20100701

• Adult onset Still's disease following influenza vaccination.

  Joint, bone, spine : revue du rhumatisme 20100701

• Blood pressure changes in patients with recent-onset rheumatoid arthritis treated with four different treatment strategies: a post hoc analysis from the BeSt trial.

  Annals of the rheumatic diseases 20100701

• A 78-joints ultrasonographic assessment is associated with clinical assessments and is highly responsive to improvement in a longitudinal study of patients with rheumatoid arthritis starting adalimumab treatment.

  Annals of the rheumatic diseases 20100701

• Folate pathway enzyme gene polymorphisms and the efficacy and toxicity of methotrexate in psoriatic arthritis.

  The Journal of rheumatology 20100701

• A 30-month-old child with acute renal failure due to primary renal cytotoxic T-cell lymphoma.

  The American journal of surgical pathology 20100701

• A matrix risk model for the prediction of rapid radiographic progression in patients with rheumatoid arthritis receiving different dynamic treatment strategies: post hoc analyses from the BeSt study.

  Annals of the rheumatic diseases 20100701

• Optical extinction combined with phase measurements for probing DNA-small-molecule interactions using an evanescent waveguide biosensor.

  Analytical chemistry 20100701

• Ten-year follow-up after intense chemoimmunotherapy with Rituximab-HyperCVAD alternating with Rituximab-high dose methotrexate/cytarabine (R-MA) and without stem cell transplantation in patients with untreated aggressive mantle cell lymphoma.

  British journal of haematology 20100701

• [Adjuvant chemotherapy in older women with breast cancer. CALGB Study (The Cancer and Leukemia Group B Study)].

  Der Internist 20100701

• 'Atypical steroid response' in a pulmonary inflammatory myofibroblastic tumor.

  Pediatric pulmonology 20100701

• Melatonin attenuates methotrexate-induced oxidative stress and renal damage in rats.

  Cell biochemistry and function 20100701

• Current concepts in the genetic diagnostics of rheumatoid arthritis.

  Expert review of molecular diagnostics 20100701

• [Primary neurolymphomatosis of the cervical nerve root].

  [Rinsho ketsueki] The Japanese journal of clinical hematology 20100701

• [Practice and consideration on neoadjuvant therapy for early breast cancer].

  Zhonghua zhong liu za zhi [Chinese journal of oncology] 20100701

• High affinity S-Adenosylmethionine plasma membrane transporter of Leishmania is a member of the folate biopterin transporter (FBT) family.

  The Journal of biological chemistry 20100625

• Folate antagonist, methotrexate induces neuronal differentiation of human embryonic stem cells transplanted into nude mouse retina.

  Neuroscience letters 20100625

• Classical cyclophosphamide, methotrexate, and fluorouracil chemotherapy is more effective in triple-negative, node-negative breast cancer: results from two randomized trials of adjuvant chemoendocrine therapy for node-negative breast cancer.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100620

• Focal skin toxicity related to methotrexate sparing psoriatic plaques.

  Dermatology online journal 20100615

• The association of reduced folate carrier 80G>A polymorphism to outcome in childhood acute lymphoblastic leukemia interacts with chromosome 21 copy number.

  Blood 20100610

• Cancer-cell-specific induction of apoptosis using mesoporous silica nanoparticles as drug-delivery vectors.

  Small (Weinheim an der Bergstrasse, Germany) 20100606

• A proteomics-based translational approach reveals an antifolate resistance inherent in human plasma derived from blood donation.

  Journal of proteome research 20100604

• [How effective is rituximab in rheumatoid arthritis?: lessons learned from clinical practice].

  Zeitschrift fur Rheumatologie 20100601

• Adverse events and factors associated with toxicity in patients with early rheumatoid arthritis treated with methotrexate tight control therapy: the CAMERA study.

  Annals of the rheumatic diseases 20100601

• Intravitreal methotrexate in therapeutically resistant exudative age-related macular degeneration.

  Acta ophthalmologica 20100601

• Neoadjuvant chemotherapy: does it have benefits for the surgeon in the treatment of advanced squamous cell cancer of the oral cavity?

  Pathology oncology research : POR 20100601

• Inflammatory bowel disease in young people: the case for transitional clinics.

  Inflammatory bowel diseases 20100601

• MACOP-B regimen in the treatment of adult Langerhans cell histiocytosis: experience on seven patients.

  Annals of oncology : official journal of the European Society for Medical Oncology 20100601

• Efficacy and safety of treatments for childhood psoriasis: a systematic literature review.

  Journal of the American Academy of Dermatology 20100601

• Treatment of adult-onset Langerhans cell histiocytosis--is it different from the pediatric approach?

  Annals of oncology : official journal of the European Society for Medical Oncology 20100601

• Usual interstitial pneumonia in rheumatoid arthritis-associated interstitial lung disease.

  The European respiratory journal 20100601

• High levels of uPA and PAI-1 predict a good response to anthracyclines.

  Breast cancer research and treatment 20100601

• An unusual case of pancreatic cancer with leptomeningeal infiltration.

  Journal of gastrointestinal cancer 20100601

• A pilot study of paternal drug exposure: the Motherisk experience.

  Reproductive toxicology (Elmsford, N.Y.) 20100601

• Synthesis of novel dendrimers having aspartate grafts and their ability to enhance the aqueous solubility of model drugs.

  European journal of medicinal chemistry 20100601

• Polymorphisms of the gamma-glutamyl hydrolase gene and risk of relapse to acute lymphoblastic leukemia in Mexico.

  Leukemia research 20100601

• Rheumatoid arthritis is an independent risk factor for increased carotid intima-media thickness: impact of anti-inflammatory treatment.

  Rheumatology (Oxford, England) 20100601

• Alterations on peripheral blood B-cell subpopulations in very early arthritis patients.

  Rheumatology (Oxford, England) 20100601

• Proposing an algorithm for treatment of different manifestations of neuro-Behcet's disease.

  Clinical rheumatology 20100601

• Intrathecal methotrexate induces focal cognitive deficits and increases cerebrospinal fluid homocysteine.

  Pharmacology, biochemistry, and behavior 20100601

• Weekly methotrexate (50mg/m(2)) without dose escalation as a primary regimen for low-risk gestational trophoblastic neoplasia.

  Gynecologic oncology 20100601

• Hyperperfusion on magnetic resonance imaging in acute chemotherapy-related leukoencephalopathy.

  Journal of child neurology 20100601

• Polymorphisms within the folate pathway predict folate concentrations but are not associated with disease activity in rheumatoid arthritis patients on methotrexate.

  Pharmacogenetics and genomics 20100601

• Treatment approaches for primary CNS lymphomas.

  Expert opinion on pharmacotherapy 20100601

• Continued inhibition of structural damage over 2 years in patients with rheumatoid arthritis treated with rituximab in combination with methotrexate.

  Annals of the rheumatic diseases 20100601

• Current evidence for the management of rheumatoid arthritis with synthetic disease-modifying antirheumatic drugs: a systematic literature review informing the EULAR recommendations for the management of rheumatoid arthritis.

  Annals of the rheumatic diseases 20100601

• Protective effect of beta-carotene on methotrexate-induced oxidative liver damage.

  Toxicologic pathology 20100601

• Rituximab for peripheral ulcerative keratitis with wegener granulomatosis.

  Cornea 20100601

• Autocrine induction of invasive and metastatic phenotypes by the MIF-CXCR4 axis in drug-resistant human colon cancer cells.

  Cancer research 20100601

• Central nervous system complications during treatment of acute lymphoblastic leukemia in a single pediatric institution.

  Leukemia & lymphoma 20100601

• Results of treatment with CMA, a low intermediate regimen, in endemic Burkitt lymphomas in sub-Saharian Africa: experience of Côte d'Ivoire.

  International journal of hematology 20100601

• Evaluation of a range of anti-proliferative assays for the preclinical screening of anti-psoriatic drugs: a comparison of colorimetric and fluorimetric assays with the thymidine incorporation assay.

  Assay and drug development technologies 20100601

• Leflunomide in combination therapy for rheumatoid arthritis.

  Drug safety 20100601

• The establishment and characterization of adriamycin-resistant cell lines derived from Saos-2.

  Medical science monitor : international medical journal of experimental and clinical research 20100601

• [Reactivation of tuberculosis with Mycobacterium bovis infection of the oral mucosa during immunosuppression].

  Deutsche medizinische Wochenschrift (1946) 20100601

• Simultaneous detection of intracellular target and off-target binding of small molecule cancer drugs at nanomolar concentrations.

  British journal of pharmacology 20100601

• Study on absorption sites of quinidine and methotrexate in rat intestine.

  Die Pharmazie 20100601

• Subcutaneous panniculitis-like T-cell lymphoma in a 19 month-old boy: a case report.

  Collegium antropologicum 20100601

• Clinical features of multiple myeloma invasion of the central nervous system in Chinese patients.

  Chinese medical journal 20100601

• Glutathione transport is a unique function of the ATP-binding cassette protein ABCG2.

  The Journal of biological chemistry 20100528

• Generation of stable cell lines by site-specific integration of transgenes into engineered Chinese hamster ovary strains using an FLP-FRT system.

  Journal of biotechnology 20100517

• Methotrexate for primary biliary cirrhosis.

  The Cochrane database of systematic reviews 20100512

• Total skin electron beam and non-myeloablative allogeneic hematopoietic stem-cell transplantation in advanced mycosis fungoides and Sezary syndrome.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100510

• Evaluation of enteropathy-associated T-cell lymphoma comparing standard therapies with a novel regimen including autologous stem cell transplantation.

  Blood 20100506

• Prognostic and predictive impact of central necrosis and fibrosis in early breast cancer: results from two International Breast Cancer Study Group randomized trials of chemoendocrine adjuvant therapy.

  Breast cancer research and treatment 20100501

• Survival, comorbidities and joint damage 11 years after the COBRA combination therapy trial in early rheumatoid arthritis.

  Annals of the rheumatic diseases 20100501

• Fibroblastic rheumatism: fibromatosis rather than non-Langerhans cell histiocytosis.

  Journal of cutaneous pathology 20100501

• Oxidative stress and enhanced paracellular permeability in the small intestine of methotrexate-treated rats.

  Cancer chemotherapy and pharmacology 20100501

• Effects of extracellular purines on cytotoxicity of methotrexate.

  Cancer chemotherapy and pharmacology 20100501

• Clinical potency of methotrexate, aminopterin, talotrexin and pemetrexed in childhood leukemias.

  Cancer chemotherapy and pharmacology 20100501

• Methotrexate-induced myelopathy responsive to substitution of multiple folate metabolites.

  Journal of neuro-oncology 20100501

• Repair of erosions occurs almost exclusively in damaged joints without swelling.

  Annals of the rheumatic diseases 20100501

• Primary multiple cerebral invasion in acute promyelocytic leukemia dramatically worsened by all-trans retinoic acid.

  Leukemia research 20100501

• Front-line high-dose chemotherapy with rituximab showed excellent long-term survival in adults with aggressive large b-cell lymphoma: final results of a Phase II GOELAMS Study.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20100501

• [Evaluation of the protocol CMA reinforced in the treatment of endemic Burkitt lymphoma at CHU of Yopougon in Abidjan].

  Bulletin du cancer 20100501

• Comparison of combination therapies in the treatment of rheumatoid arthritis: leflunomide-anti-TNF-alpha versus methotrexate-anti-TNF-alpha.

  Clinical rheumatology 20100501

• Cyclophosphamide, methotrexate, and fluorouracil; oral cyclophosphamide; levamisole; or no adjuvant therapy for patients with high-risk, premenopausal breast cancer.

  Cancer 20100501

• Adherence to disease-modifying antirheumatic drugs and the effects of exposure misclassification on the risk of hospital admission.

  Arthritis care & research 20100501

• Apical leptin induces chloride secretion by intestinal epithelial cells and in a rat model of acute chemotherapy-induced colitis.

  American journal of physiology. Gastrointestinal and liver physiology 20100501

• Clinicopathologic correlations of diffuse large B-cell lymphoma in rheumatoid arthritis patients treated with methotrexate.

  Cancer science 20100501

• Advanced penile verrucous carcinoma treated with intra-aortic infusion chemotherapy.

  The Journal of urology 20100501

• Medical management of polymyalgia rheumatica.

  Expert opinion on pharmacotherapy 20100501

• Large granular lymphocyte leukemia: natural history and response to treatment.

  Leukemia & lymphoma 20100501

• Genetic determinants of methotrexate treatment in rheumatoid arthritis patients: a study of polymorphisms in the adenosine pathway.

  Annals of the rheumatic diseases 20100501

• Prospective study of hemostatic alterations in children with acute lymphoblastic leukemia.

  American journal of hematology 20100501

• Neurological complications during treatment of childhood cancer: mind Wernicke encephalopathy.

  Pediatric hematology and oncology 20100501

• Race and methotrexate pharmacogenetics in rheumatoid arthritis.

  The Journal of rheumatology 20100501

• Early-stage testicular cancer: a rare association with dermatomyositis.

  The Australasian journal of dermatology 20100501

• Route of intracerebrospinal fluid chemotherapy administration and efficacy of therapy in neoplastic meningitis.

  Cancer 20100415

• Optimised mammalian expression through the coupling of codon adaptation with gene amplification: maximum yields with minimum effort.

  Journal of biotechnology 20100415

• Non-classical antifolates. Part 2: synthesis, biological evaluation, and molecular modeling study of some new 2,6-substituted-quinazolin-4-ones.

  Bioorganic & medicinal chemistry 20100415

• Hazards of concomitant administration of methotrexate and glutamine.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20100415

• [A cutaneous infection by Mycobacterium chelonae in a patient with rheumatoid arthritis].

  Dermatology online journal 20100415

• Benefits of the intermittent use of 6-mercaptopurine and methotrexate in maintenance treatment for low-risk acute lymphoblastic leukemia in children: randomized trial from the Brazilian Childhood Cooperative Group--protocol ALL-99.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100410

• Oral 6-mercaptopurine versus oral 6-thioguanine and veno-occlusive disease in children with standard-risk acute lymphoblastic leukemia: report of the Children's Oncology Group CCG-1952 clinical trial.

  Blood 20100408

• Selection for methotrexate resistance in mammalian cells bearing a Drosophila dihydrofolate reductase transgene: Methotrexate resistance in transgenic mammalian cells.

  Cell biology and toxicology 20100401

• Abatacept as an option therapy in difficult to treat psoriatic arthritis.

  Rheumatology international 20100401

• Optimization of the non-invasive 13C-sucrose breath test in a rat model of methotrexate-induced mucositis.

  Cancer chemotherapy and pharmacology 20100401

• Growth fraction as a predictor of response to chemotherapy in node-negative breast cancer.

  International journal of cancer 20100401

• [Visceral leishmaniasis infection in a rheumatoid arthritis patient treated with adalimumab: a case description and literature review].

  Enfermedades infecciosas y microbiologia clinica 20100401

• Long-term follow-up of an age-adapted C5R protocol followed by radiotherapy in 99 newly diagnosed primary CNS lymphomas: a prospective multicentric phase II study of the Groupe d'Etude des Lymphomes de l'Adulte (GELA).

  Annals of oncology : official journal of the European Society for Medical Oncology 20100401

• In vitro and in vivo study on the antioxidant activity of dexrazoxane.

  Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20100401

• Working memory in survivors of childhood acute lymphocytic leukemia: functional neuroimaging analyses.

  Pediatric blood & cancer 20100401

• Central nervous system involvement at the time of presentation in acute promyelocytic leukemia.

  Pediatric blood & cancer 20100401

• Activity and safety of combination chemotherapy with methotrexate, ifosfamide, l-asparaginase and dexamethasone (MILD) for refractory lymphoid malignancies: a pilot study.

  European journal of haematology 20100401

• Prospective bone ultrasound patterns during childhood acute lymphoblastic leukemia treatment.

  Bone 20100401

• Ongoing remission after intensive ALL-type chemotherapy in pediatric intestinal T-cell lymphoma.

  Pediatric blood & cancer 20100401

• Endogenous folates and single-carbon metabolism in the ovarian follicle, oocyte and pre-implantation embryo.

  Reproduction (Cambridge, England) 20100401

• The degree of myelosuppression during maintenance therapy of adolescents with B-lineage intermediate risk acute lymphoblastic leukemia predicts risk of relapse.

  Leukemia 20100401

• Relationship of the reduced folate carrier gene polymorphism G80A to methotrexate plasma concentration, toxicity, and disease outcome in childhood acute lymphoblastic leukemia.

  Leukemia & lymphoma 20100401

• Effectiveness and toxicity of methotrexate in juvenile idiopathic arthritis: comparison of 2 initial dosing regimens.

  The Journal of rheumatology 20100401

• Dose-intensified treatment of Burkitt lymphoma and B-cell lymphoma unclassifiable, (with features intermediate between diffuse large B-cell lymphoma and Burkitt lymphoma) in young adults (<50 years): a comparison of two adapted BFM protocols.

  American journal of hematology 20100401

• [Portal hypertension in patients with inflammatory bowel disease].

  Gastroenterologia y hepatologia 20100401

• Comparative study of two mechlorethamine, vincristine, procarbazine, and prednisone derived chemotherapeutic protocols for the management of pediatric Hodgkin lymphoma (HL): single-center 5-year experience.

  Leukemia & lymphoma 20100401

• Successful treatment of extranodal natural killer/T-cell lymphoma, nasal type, complicated by severe hemophagocytic syndrome, with dexamethasone, methotrexate, ifosfamide, L-asparaginase, and etoposide chemotherapy followed by autologous stem cell transplant.

  Leukemia & lymphoma 20100401

• Solar burn reactivation induced by methotrexate.

  Pharmacotherapy 20100401

• Cotton wool spots as an indicator of methotrexate-induced blood dyscrasia.

  Optometry (St. Louis, Mo.) 20100401

• Solitary intradural extramedullary lymphoma of the cervical spine.

  Journal of neurosurgery. Spine 20100401

• Early disease control by low-dose prednisone comedication may affect the quality of remission in patients with early rheumatoid arthritis.

  Annals of the New York Academy of Sciences 20100401

• [Prophylactic effect of CsA, MTX, MMF combined with ATG on GVHD in patients underwent unrelated peripheral blood hematopoietic stem cell transplantation].

  Zhongguo shi yan xue ye xue za zhi 20100401

• Simultaneous detection of MDR1 and WT1 gene expression to predict the prognosis of adult acute lymphoblastic leukemia.

  Hematology (Amsterdam, Netherlands) 20100401

• A case of normal-pressure hydrocephalus associated with rheumatoid arthritis.

  Aging clinical and experimental research 20100401

• [Annular rectal constriction caused by infiltrating bladder carcinoma: a case report].

  Hinyokika kiyo. Acta urologica Japonica 20100401

• Perioperative management of the patient with rheumatoid arthritis.

  Clinics in podiatric medicine and surgery 20100401

• New-onset psoriasis associated with etanercept therapy.

  The Journal of dermatology 20100401

• [Prescription and surveillance of treatment by a systemic agent or biotherapy in psoriasis].

  Annales de dermatologie et de venereologie 20100401

• Excellent immunological recovery following CODOX-M/IVAC, an effective intensive chemotherapy for HIV-associated Burkitt's lymphoma.

  AIDS (London, England) 20100327

• [Rheumatoid arthritis, methothrexate, and pulmonary fibrosis: which evidences?].

  Revue medicale suisse 20100317

• Methotrexate reduces hippocampal blood vessel density and activates microglia in rats but does not elevate central cytokine release.

  Behavioural brain research 20100305

• Nuclear magnetic resonance study of the role of M42 in the solution dynamics of Escherichia coli dihydrofolate reductase.

  Biochemistry 20100302

• Proanthocyanidin prevents methotrexate-induced intestinal damage and oxidative stress.

  Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20100301

• Infliximab for reactive arthritis secondary to Chlamydia trachomatis infection.

  Rheumatology international 20100301

• Prevalence of positive ppd in a cohort of rheumatoid arthritis patients.

  Rheumatology international 20100301

• Dose-dense therapy improves survival in aggressive non-Hodgkin's lymphoma.

  Annals of hematology 20100301

• Inflammatory myofibroblastic tumor of the conjunctiva: response to chemotherapy with low-dose methotrexate and vinorelbine.

  Pediatric blood & cancer 20100301

• Diffuse large B-cell lymphoma of the central nervous system in mycophenolate mofetil-treated patients with systemic lupus erythematosus.

  Lupus 20100301

• Central nervous system T-cell lymphoma in acquired immunodeficiency syndrome.

  British journal of haematology 20100301

• Acute transverse myelitis in psoriatic arthritis.

  Journal of neurology 20100301

• High rate and prolonged duration of complete remissions induced by rituximab, methotrexate, doxorubicin, cyclophosphamide, vincristine, ifosfamide, etoposide, cytarabine, and thalidomide (R-MACLO-IVAM-T), a modification of the National Cancer Institute 89-C-41 regimen, in patients with newly diagnosed mantle cell lymphoma.

  Leukemia & lymphoma 20100301

• Long term outcome of patients with localized aggressive non-Hodgkin lymphoma treated with PROMECE-CYTABOM plus involved-field radiation therapy: a study by the Gruppo Italiano Studio Linfomi.

  Leukemia & lymphoma 20100301

• Anticancer agents against malaria: time to revisit?

  Trends in parasitology 20100301

• Cyclin-dependent kinase inhibitor SU9516 enhances sensitivity to methotrexate in human T-cell leukemia Jurkat cells.

  Cancer science 20100301

• Histone deacetylase inhibitors induce FPGS mRNA expression and intracellular accumulation of long-chain methotrexate polyglutamates in childhood acute lymphoblastic leukemia: implications for combination therapy.

  Leukemia 20100301

• Effects of acute or chronic exposure to dietary organic anions on secretion of methotrexate and salicylate by Malpighian tubules of Drosophila melanogaster larvae.

  Archives of insect biochemistry and physiology 20100301

• Clinical improvement in rheumatoid arthritis is associated with healthier microvascular function in patients who respond to antirheumatic therapy.

  The Journal of rheumatology 20100301

• Phase 2 trial of primary systemic therapy with doxorubicin and docetaxel followed by surgery, radiotherapy, and adjuvant chemotherapy with cyclophosphamide, methotrexate, and 5-fluorouracil based on clinical and pathologic response in patients with stage IIB to III breast cancer : long-term results from the University of Texas M. D. Anderson Cancer Center Study ID97-099.

  Cancer 20100301

• Functional characterization and virulence study of ADE8 and GUA1 genes involved in the de novo purine biosynthesis in Candida albicans.

  FEMS yeast research 20100301

• Oxidative stress and protective effect of erythropoietin on methotrexate-induced esophageal damage.

  Journal of pediatric hematology/oncology 20100301

• Comparative renal excretion of VX-702, a novel p38 MAPK inhibitor, and methotrexate in the perfused rat kidney model.

  Drug development and industrial pharmacy 20100301

• Targeting Alzheimer's disease: Novel indanone hybrids bearing a pharmacophoric fragment of AP2238.

  Bioorganic & medicinal chemistry 20100301

• Significance of myeloid antigen expression in precursor T lymphoblastic lymphoma.

  Chinese journal of cancer 20100301

• Methotrexate--how does it really work?

  Nature reviews. Rheumatology 20100301

• Comparison of peripheral blood stem cell transplant with bone marrow transplant in class 3 thalassemic patients.

  Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20100301

• [A case of recurrent breast cancer with life-threatening liver metastasis remarkably responding to classical CMF].

  Gan to kagaku ryoho. Cancer & chemotherapy 20100301

• [A case of multidrug-resistant breast cancer associated with multiple hepatic and bone metastases for which cyclophosphamide, methotrexate, and 5-fluorouracil chemotherapy proved effective].

  Gan to kagaku ryoho. Cancer & chemotherapy 20100301

• Painful nail lesions.

  Australian family physician 20100301

• [Successful treatment with hyper-CVAD and highly active anti-retroviral therapy (HAART) for AIDS-related Burkitt lymphoma].

  [Rinsho ketsueki] The Japanese journal of clinical hematology 20100301

• Severe intoxication with methotrexate possibly associated with concomitant use of proton pump inhibitors.

  Anticancer research 20100301

• Evidence for the hypothesis that 10-formyldihydrofolate is the in vivo substrate for aminoimidazolecarboxamide ribotide transformylase.

  Experimental biology and medicine (Maywood, N.J.) 20100301

• Erythema gyratum repens-like eruption occuring in resolving psoriasis during methotrexate therapy.

  International journal of dermatology 20100301

• Patch testing in patients treated with systemic immunosuppression and cytokine inhibitors.

  Contact dermatitis 20100301

• Single agents with designed combination chemotherapy potential: synthesis and evaluation of substituted pyrimido[4,5-b]indoles as receptor tyrosine kinase and thymidylate synthase inhibitors and as antitumor agents.

  Journal of medicinal chemistry 20100225

• HER2, TOP2A, and TIMP-1 and responsiveness to adjuvant anthracycline-containing chemotherapy in high-risk breast cancer patients.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100220

• Methotrexate area under the curve is an important outcome predictor in patients with primary CNS lymphoma: A pharmacokinetic-pharmacodynamic analysis from the IELSG no. 20 trial.

  British journal of cancer 20100216

• A case of aseptic pleuropericarditis in a patient with chronic plaque psoriasis under methotrexate therapy.

  Dermatology online journal 20100215

• Synthesis and antitumor activity of a novel series of 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl antifolate inhibitors of purine biosynthesis with selectivity for high affinity folate receptors and the proton-coupled folate transporter over the reduced folate carrier for cellular entry.

  Journal of medicinal chemistry 20100211

• Phase I/II trial of metronomic chemotherapy with daily dalteparin and cyclophosphamide, twice-weekly methotrexate, and daily prednisone as therapy for metastatic breast cancer using vascular endothelial growth factor and soluble vascular endothelial growth factor receptor levels as markers of response.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100210

• Efficacy and safety of pamapimod in patients with active rheumatoid arthritis receiving stable methotrexate therapy.

  Annals of the rheumatic diseases 20100201

• Association of methotrexate and tumour necrosis factor antagonists with risk of infectious outcomes including opportunistic infections in the CORRONA registry.

  Annals of the rheumatic diseases 20100201

• An analysis of hydrophobic interactions of thymidylate synthase with methotrexate: free energy calculations involving mutant and native structures bound to methotrexate.

  Journal of molecular modeling 20100201

• Toxic non-resorptive internal hydrocephalus as a result of haemorrhagic ventriculitis during induction chemotherapy of Bcr-Abl positive acute lymphoblastic leukaemia.

  Annals of hematology 20100201

• Adverse prognostic value of peritumoral vascular invasion: is it abrogated by adequate endocrine adjuvant therapy? Results from two International Breast Cancer Study Group randomized trials of chemoendocrine adjuvant therapy for early breast cancer.

  Annals of oncology : official journal of the European Society for Medical Oncology 20100201

• Sequential chemotherapy with methotrexate and 5-fluorouracil for chemotherapy-naive advanced gastric cancer with disseminated intravascular coagulation at initial diagnosis.

  Journal of cancer research and clinical oncology 20100201

• The human proton-coupled folate transporter (hPCFT): modulation of intestinal expression and function by drugs.

  American journal of physiology. Gastrointestinal and liver physiology 20100201

• Acute respiratory distress syndrome associated with rapid aggravation of rheumatoid arthritis.

  Modern rheumatology 20100201

• Improved outcomes using tacrolimus/sirolimus for graft-versus-host disease prophylaxis with a reduced-intensity conditioning regimen for allogeneic hematopoietic cell transplant as treatment of myelofibrosis.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20100201

• In vivo selection of human embryonic stem cell-derived cells expressing methotrexate-resistant dihydrofolate reductase.

  Gene therapy 20100201

• Efficacy of oral tegafur-uracil (UFT) as adjuvant therapy as compared with classical cyclophosphamide, methotrexate, and 5-fluorouracil (CMF) in early breast cancer: a pooled analysis of two randomized controlled trials (N.SAS-BC 01 trial and CUBC trial).

  Breast cancer research and treatment 20100201

• Peripheral blood expression profiles of bone morphogenetic proteins, tumor necrosis factor-superfamily molecules, and transcription factor Runx2 could be used as markers of the form of arthritis, disease activity, and therapeutic responsiveness.

  The Journal of rheumatology 20100201

• Targeting the efficacy of a dendrimer-based nanotherapeutic in heterogeneous xenograft tumors in vivo.

  Anti-cancer drugs 20100201

• Serum amyloid A is a useful marker to evaluate the disease activity of Takayasu's arteritis.

  Rheumatology international 20100201

• Clarithromycin in adult-onset Still's disease: a study of 6 cases.

  Rheumatology international 20100201

• Raltegravir-based HAART regimen in a patient with large B-cell lymphoma.

  The Annals of pharmacotherapy 20100201

• Rho GDP dissociation inhibitor alpha expression correlates with the outcome of CMF treatment in invasive ductal breast cancer.

  International journal of oncology 20100201

• Lupus erythematosus panniculitis: clinicopathological, immunophenotypic, and molecular studies.

  The American Journal of dermatopathology 20100201

• The selective estrogen receptor alpha agonist Org 37663 induces estrogenic effects but lacks antirheumatic activity: a phase IIa trial investigating efficacy and safety of Org 37663 in postmenopausal female rheumatoid arthritis patients receiving stable background methotrexate or sulfasalazine.

  Arthritis and rheumatism 20100201

• Methotrexate polyglutamate concentrations are not associated with disease control in rheumatoid arthritis patients receiving long-term methotrexate therapy.

  Arthritis and rheumatism 20100201

• Alopecia areata update: part II. Treatment.

  Journal of the American Academy of Dermatology 20100201

• Synthesis and characterization of methotrexate polyethylene glycol esters as a drug delivery system.

  Chemical & pharmaceutical bulletin 20100201

• Subacute methotrexate neurotoxicity and cerebral venous sinus thrombosis in a 12-year-old with acute lymphoblastic leukemia and methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism: homocysteine-mediated methotrexate neurotoxicity via direct endothelial injury.

  Pediatric hematology and oncology 20100201

• Does gastrointestinal adverse drug reaction influence therapeutic effect in the treatment of rheumatoid arthritis?

  Journal of alternative and complementary medicine (New York, N.Y.) 20100201

• Functional polymorphisms and methotrexate treatment outcome in recent-onset rheumatoid arthritis.

  Pharmacogenomics 20100201

• [Neoplastic meningitis. Diagnosis and individualised therapy].

  Der Nervenarzt 20100201

• [Effect of Chai-ling-tang (Sairei-to) for methotrexate concentration degradation delay by methotrexate high-dose therapy].

  No shinkei geka. Neurological surgery 20100201

• ANCA-associated vasculitides: advances in pathophysiology and treatment.

  The Netherlands journal of medicine 20100201

• [Complete response to M-FAP chemotherapy for multiple lung metastases after segmental resection of urachal carcinoma : a case report].

  Hinyokika kiyo. Acta urologica Japonica 20100201

• Protocols for the initial treatment of moderately severe juvenile dermatomyositis: results of a Children's Arthritis and Rheumatology Research Alliance Consensus Conference.

  Arthritis care & research 20100201

• Infliximab therapy in a patient with refractory ileocolic Crohn's disease and Takayasu arteritis.

  Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva 20100201

• [Intravascular large B-cell lymphoma with pontine involvement successfully treated with R-hyper-CVAD/R-MTX-Ara-C regimen].

  [Rinsho ketsueki] The Japanese journal of clinical hematology 20100201

• Rheumatoid arthritis: choice of antirheumatic treatment. Methotrexate first.

  Prescrire international 20100201

• Resistant pityriasis lichenoides et varioliformis acuta in a 3-year-old boy: successful treatment with methotrexate.

  International journal of dermatology 20100201

• Neoadjuvant chemotherapy with trastuzumab followed by adjuvant trastuzumab versus neoadjuvant chemotherapy alone, in patients with HER2-positive locally advanced breast cancer (the NOAH trial): a randomised controlled superiority trial with a parallel HER2-negative cohort.

  Lancet (London, England) 20100130

• Theory and normal-mode analysis of change in protein vibrational dynamics on ligand binding.

  The journal of physical chemistry. B 20100128

• Pathologic complete response rates in young women with BRCA1-positive breast cancers after neoadjuvant chemotherapy.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100120

• Re: International guidelines for management of metastatic breast cancer: combination vs sequential single-agent chemotherapy.

  Journal of the National Cancer Institute 20100120

• Development and validation of a cytochrome c-coupled assay for pteridine reductase 1 and dihydrofolate reductase.

  Analytical biochemistry 20100115

• Inhibition of histone deacetylase activity is a novel function of the antifolate drug methotrexate.

  Biochemical and biophysical research communications 20100115

• Antifolate and antiproliferative activity of 6,8,10-triazaspiro[4.5]deca-6,8-dienes and 1,3,5-triazaspiro[5.5]undeca-1,3-dienes.

  Bioorganic & medicinal chemistry 20100115

• 2,4-Diamino-5-methyl-6-substituted arylthio-furo[2,3-d]pyrimidines as novel classical and nonclassical antifolates as potential dual thymidylate synthase and dihydrofolate reductase inhibitors.

  Bioorganic & medicinal chemistry 20100115

• Structure-based design of pteridine reductase inhibitors targeting African sleeping sickness and the leishmaniases.

  Journal of medicinal chemistry 20100114

• [Drug therapy of Crohn's disease: slowly increase or start aggressively right away?].

  MMW Fortschritte der Medizin 20100114

• Dexamethasone reduces methotrexate biliary elimination and potentiates its hepatotoxicity in rats.

  Toxicology 20100112

• Arabinogalactan-folic acid-drug conjugate for targeted delivery and target-activated release of anticancer drugs to folate receptor-overexpressing cells.

  Biomacromolecules 20100111

• Intervention of alpha-lipoic acid ameliorates methotrexate-induced oxidative stress and genotoxicity: A study in rat intestine.

  Chemico-biological interactions 20100105

• Assessment of residual tumour by FDG-PET: conventional imaging and clinical examination following primary chemotherapy of large and locally advanced breast cancer.

  British journal of cancer 20100105

• Methotrexate, paclitaxel, ifosfamide, and cisplatin in poor-risk nonseminomatous germ cell tumors.

  Urologic oncology 20100101

• Elevated liver enzyme tests among patients with rheumatoid arthritis or psoriatic arthritis treated with methotrexate and/or leflunomide.

  Annals of the rheumatic diseases 20100101

• TWEAK and its receptor Fn14 in the synovium of patients with rheumatoid arthritis compared to psoriatic arthritis and its response to tumour necrosis factor blockade.

  Annals of the rheumatic diseases 20100101

• Comparison of tocilizumab monotherapy versus methotrexate monotherapy in patients with moderate to severe rheumatoid arthritis: the AMBITION study.

  Annals of the rheumatic diseases 20100101

• [Bing-Neel syndrome revealing Waldenström's macroglobulinemia].

  Revue neurologique 20100101

• The effect of infliximab on antiviral antibody profiles in patients with rheumatoid arthritis.

  Rheumatology international 20100101

• Low-dose methotrexate treatment for moderate-to-severe atopic dermatitis in adults.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20100101

• Primary brain T-cell lymphoma of the lymphoblastic type presenting as altered mental status.

  Acta neurochirurgica 20100101

• Epstein-Barr virus negative large B-cell lymphoma during long term immunomodulatory therapy for T-cell large granular lymphocytic leukaemia.

  British journal of haematology 20100101

• Evaluation of the late effects of CNS prophylactic treatment in childhood acute lymphoblastic leukemia (ALL) using magnetic resonance spectroscopy.

  Acta neurochirurgica. Supplement 20100101

• Effect of allopurinol versus urate oxidase on methotrexate pharmacokinetics in children with newly diagnosed acute lymphoblastic leukemia.

  Cancer 20100101

• Dose-intensified epirubicin versus standard-dose epirubicin/cyclophosphamide followed by CMF in breast cancer patients with 10 or more positive lymph nodes: results of a randomised trial (GABG-IV E-93) - the German Adjuvant Breast Cancer Group.

  European journal of cancer (Oxford, England : 1990) 20100101

• Systemic methotrexate induces spatial memory deficits and depletes cerebrospinal fluid folate in rats.

  Pharmacology, biochemistry, and behavior 20100101

• [Hepatotoxicity induced by new immunosuppressants].

  Gastroenterologia y hepatologia 20100101

• Methotrexate: a useful steroid-sparing agent in recalcitrant chronic urticaria.

  The British journal of dermatology 20100101

• Methylene tetrahydrofolate reductase gene polymorphism in Egyptian children with acute lymphoblastic leukemia.

  Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20100101

• Glucarpidase following high-dose methotrexate: update on development.

  Expert opinion on biological therapy 20100101

• Aggressive fibromatosis in children and adolescents: the Italian experience.

  Cancer 20100101

• Decrease of adenosine deaminase activity and increase of the lipid peroxidation after acute methotrexate treatment in young rats: protective effects of grape seed extract.

  Cell biochemistry and function 20100101

• Treatment of methotrexate intoxication with various modalities of continuous extracorporeal therapy and glucarpidase.

  Pharmacotherapy 20100101

• Novel role of plasmacytoid dendritic cells in humans: induction of interleukin-10-producing Treg cells by plasmacytoid dendritic cells in patients with rheumatoid arthritis responding to therapy.

  Arthritis and rheumatism 20100101

• Associations between the C677T and A1298C polymorphisms of MTHFR and the efficacy and toxicity of methotrexate in rheumatoid arthritis: a meta-analysis.

  Clinical drug investigation 20100101

• Liquid chromatography-tandem mass spectrometry (LC-MS-MS) method for monitoring methotrexate in the setting of carboxypeptidase-G2 therapy.

  Methods in molecular biology (Clifton, N.J.) 20100101

• Therapeutic usefulness of postoperative adjuvant chemotherapy with Tegafur-Uracil (UFT) in patients with breast cancer: focus on the results of clinical studies in Japan.

  The oncologist 20100101

• Malignancy concerns with psoriasis treatments using phototherapy, methotrexate, cyclosporin, and biologics: facts and controversies.

  Clinics in dermatology 20100101

• Traditional herbal medicines (Kampo) for patients with rheumatoid arthritis receiving concomitant methotrexate: a preliminary study.

  Alternative therapies in health and medicine 20100101

• [Therapeutic effects of vinorelbine-based chemotherapy--retrospective study of 65 patients with metastatic or relapsed breast cancer].

  Gan to kagaku ryoho. Cancer & chemotherapy 20100101

• Diffuse bilateral orbital inflammation in Churg- Strauss syndrome.

  Ophthalmic plastic and reconstructive surgery 20100101

• Increased expression of proto-oncogene survivin predicts Joint destruction and persistent disease activity in early rheumatoid arthritis.

  Annals of medicine 20100101

• Treatment of acrodermatitis continua of Hallopeau with TNF-blocking agents: case report and review.

  Dermatology (Basel, Switzerland) 20100101

• Mycobacterial hand infections occurring postoperatively in patients treated with tumor necrosis factor-alpha inhibitors for inflammatory arthritis: report of three cases.

  The Journal of hand surgery 20100101

• Atypical presentation of histoplasmosis in a patient with psoriasis and psoriatic arthritis on infliximab therapy.

  Journal of drugs in dermatology : JDD 20100101

• Prolonged disease control after myeloablative chemotherapy, autologous transplantation and immunotherapy in high-risk early breast cancer.

  Anticancer research 20100101

• Neoadjuvant multidrug chemotherapy including high-dose methotrexate modifies VEGF expression in osteosarcoma: an immunohistochemical analysis.

  BMC musculoskeletal disorders 20100101

• Defining conditions for the co-culture of Caco-2 and HT29-MTX cells using Taguchi design.

  Journal of pharmacological and toxicological methods 20100101

• Case of localized scleroderma successfully treated with bath psoralen and ultraviolet A therapy.

  The Journal of dermatology 20100101

• [Evaluation of unresponsiveness to standard high-dose gamma globulin therapy in Kawasaki disease].

  Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir 20100101

• Effect of early treatment in polymyositis and dermatomyositis.

  Neurology India 20100101

• A phase II study of high-dose celecoxib and metronomic 'low-dose' cyclophosphamide and methotrexate in patients with relapsed and refractory lymphoma.

  Hematology/oncology and stem cell therapy 20100101

• [Immunosuppressive therapy and tuberculosis].

  Kekkaku : [Tuberculosis] 20100101

• Combination of calcipotriol and methotrexate in nanostructured lipid carriers for topical delivery.

  International journal of nanomedicine 20100101

• Leg ulceration in rheumatoid arthritis--an underreported multicausal complication with considerable morbidity: analysis of thirty-six patients and review of the literature.

  Dermatology (Basel, Switzerland) 20100101

• Renal safety of initial combination versus single DMARD therapy in patients with early rheumatoid arthritis: an 11-year experience from the FIN-RACo Trial.

  Clinical and experimental rheumatology 20100101

• Good prognosis for primary ovarian pure nongestational choriocarcinoma using the EMA/CO regime.

  European journal of gynaecological oncology 20100101

• Biology-driven cancer drug development: back to the future.

  BMC biology 20100101

• Immunomodulatory drugs regulate HMGB1 release from activated human monocytes.

  Molecular medicine (Cambridge, Mass.) 20100101

• Clinical evidence for overcoming capecitabine resistance in a woman with breast cancer terminating in radiologically occult micronodular pseudo-cirrhosis with portal hypertension: a case report.

  Journal of medical case reports 20100101

• Methotrexate plus leflunomide for the treatment of relapsingWegener's granulomatosis. A retrospective uncontrolled study.

  Clinical and experimental rheumatology 20100101

• Primary Burkitt's lymphoma of the ovary.

  African journal of paediatric surgery : AJPS 20100101

• Molecular mechanism of chemoresistance by miR-215 in osteosarcoma and colon cancer cells.

  Molecular cancer 20100101

• Knockout of the folate transporter folt-1 causes germline and somatic defects in C. elegans.

  BMC developmental biology 20100101

• Testicular relapse in childhood acute lymphoblastic leukemia: the challenges and lessons.

  Indian journal of cancer 20100101

• Adult-Onset Still Disease (AOSD).

  Journal of the American Board of Family Medicine : JABFM 20100101

• Seven-year follow-up of infliximab therapy in rheumatoid arthritis patients with severe long-standing refractory disease: attrition rate and evolution of disease activity.

  Arthritis research & therapy 20100101

• Transport of aminopterin by human organic anion transporters hOAT1 and hOAT3: Comparison with methotrexate.

  Drug metabolism and pharmacokinetics 20100101

• [Immunosuppressive agents in Dermatology].

  Anais brasileiros de dermatologia 20100101

• Cytomegalovirus-induced infectious mononucleosis-like syndrome in a rheumatoid arthritis patient treated with methotrexate and infliximab.

  Internal medicine (Tokyo, Japan) 20100101

• Non-Hodgkin's lymphoma: is India ready to incorporate recent advances in day to day practice?

  Journal of cancer research and therapeutics 20100101

• Accelerated hand bone mineral density loss is associated with progressive joint damage in hands and feet in recent-onset rheumatoid arthritis.

  Arthritis research & therapy 20100101

• [Polymyalgia rheumatica: new possibilities for treatment, but not diagnosis].

  Nederlands tijdschrift voor geneeskunde 20100101

• Overexpression of S100A4 in human cancer cell lines resistant to methotrexate.

  BMC cancer 20100101

• Carmustine and methotrexate in combination after whole brain radiation therapy in breast cancer patients presenting with brain metastases: a retrospective study.

  BMC cancer 20100101

• Vaccination with a plasmid DNA encoding HER-2/neu together with low doses of GM-CSF and IL-2 in patients with metastatic breast carcinoma: a pilot clinical trial.

  Journal of translational medicine 20100101

• Epirubicin followed by cyclophosphamide, methotrexate and 5-fluorouracil versus paclitaxel followed by epirubicin and vinorelbine in patients with high-risk operable breast cancer.

  Oncology 20100101

• Combined effects of UVR and temperature on the survival of crab larvae (Zoea I) from Patagonia: the role of uv-absorbing compounds.

  Marine drugs 20100101

• Acral erythema with bullous formation: a side effect of chemotherapy in a child with acute lymphoblastic leukemia.

  The Turkish journal of pediatrics 20100101

• 74-week follow-up of safety of infliximab in patients with refractory rheumatoid arthritis.

  Arthritis research & therapy 20100101

• Expression of phosphatidylserine-specific phospholipase A(1) mRNA in human THP-1-derived macrophages.

  Cell transplantation 20100101

• Early combination disease-modifying antirheumatic drug therapy and tight disease control improve long-term radiologic outcome in patients with early rheumatoid arthritis: the 11-year results of the Finnish Rheumatoid Arthritis Combination Therapy trial.

  Arthritis research & therapy 20100101

• A prospective, randomised, controlled, double-blind phase I-II clinical trial on the safety of A-Part Gel as adhesion prophylaxis after major abdominal surgery versus non-treated group.

  BMC surgery 20100101

• Febrile ulceronecrotic Mucha-Habermann's disease with pulmonary involvement.

  Pediatric dermatology 20100101

• Stereoselective transport of amethopterin enantiomers by the proton-coupled folate transporter.

  Drug metabolism and pharmacokinetics 20100101

• [The goal for the treatment of rheumatoid arthritis should be remission].

  Duodecim; laaketieteellinen aikakauskirja 20100101

• [Diagnosis and management of small vessel vasculitides].

  Duodecim; laaketieteellinen aikakauskirja 20100101

• 30 years' experience in the treatment of low-risk gestational trophoblastic neoplasia in Hungary.

  The Journal of reproductive medicine 20100101

• Rare incidence of methotrexate-specific lesions in liver biopsy of patients with arthritis and elevated liver enzymes.

  Arthritis research & therapy 20100101

• Liposomal encapsulation enhances and prolongs the anti-inflammatory effects of water-soluble dexamethasone phosphate in experimental adjuvant arthritis.

  Arthritis research & therapy 20100101

• Rheumatologists' recommended patient information when prescribing methotrexate for rheumatoid arthritis.

  Clinical and experimental rheumatology 20100101

• High-dose immunoglobulines and extracorporeal photochemotherapy in the treatment of febrile ulceronecrotic Mucha-Habermann disease.

  Dermatologic therapy 20100101

• Adjuvant radiotherapy and chemotherapy in breast cancer: 30 year follow-up of survival.

  BMC cancer 20100101

• IGF-II mRNA expression in breast cancer: predictive value and relationship to other prognostic factors.

  The International journal of biological markers 20100101

• [Therapeutic drug monitoring of methotrexate after its administration in high-dose protocols].

  Therapie 20100101

• Drug-induced secondary cataract prevention: experimental ex vivo and in vivo results with disulfiram, methotrexate and actinomycin D.

  Ophthalmic research 20100101

• Comparison of the multi-drug resistant human hepatocellular carcinoma cell line Bel-7402/ADM model established by three methods.

  Journal of experimental & clinical cancer research : CR 20100101

• Low-risk gestational trophoblastic neoplasia and methotrexate resistance: predictors of response to treatment with actinomycin D and need for combination chemotherapy.

  The Journal of reproductive medicine 20100101

• Management of drug resistant gestational trophoblastic neoplasia.

  The Journal of reproductive medicine 20100101

• Recurrent gestational trophoblastic disease in a case of suspected quiescent gestational trophoblastic disease: a case report.

  The Journal of reproductive medicine 20100101

• High-risk gestational trophoblastic neoplasia at Gujarat Cancer and Research Institute: thirteen years of experience.

  The Journal of reproductive medicine 20100101

• Localized severe scleroderma: a retrospective study of 26 pediatric patients.

  Pediatric dermatology 20100101

• [Long-term follow-up of the efficacy of methotrexate alone or in combination with low doses of oral corticosteroids in the treatment of alopecia areata totalis or universalis].

  Annales de dermatologie et de venereologie 20100101

• Overexpression of inosine 5'-monophosphate dehydrogenase type II mediates chemoresistance to human osteosarcoma cells.

  PloS one 20100101

• Resveratrol protects against methotrexate-induced hepatic injury in rats.

  Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20100101

• Successful allogeneic hematopoietic stem cell transplantation for aggressive NK cell leukemia.

  Internal medicine (Tokyo, Japan) 20100101

• Comparison of three adjuvant chemotherapy regimes using an extended log-logistic model in women with operable breast cancer.

  Asian Pacific journal of cancer prevention : APJCP 20100101

• Strongyloides stercoralis hyperinfection in a patient with rheumatoid arthritis and bronchial asthma: a case report.

  Annals of clinical microbiology and antimicrobials 20100101

• [Systemic therapy in the treatment of psoriasis: drugs of prebiological era].

  Lijecnicki vjesnik 20100101

• Associations between the genetic polymorphisms of MTHFR and outcomes of methotrexate treatment in rheumatoid arthritis.

  Clinical and experimental rheumatology 20100101

• Inhibitory effect of selective cyclooxygenase-2 inhibitor lumiracoxib on human organic anion transporters hOAT1 and hOAT3.

  Drug metabolism and pharmacokinetics 20100101

• Curcumin protects intestinal mucosal barrier function of rat enteritis via activation of MKP-1 and attenuation of p38 and NF-κB activation.

  PloS one 20100101

• Improved survival with combined chemo-radiotherapy in primary central nervous system lymphoma.

  Hematology/oncology and stem cell therapy 20100101

• [Cancer treatment-induced nephrotoxicity: BCR-Abl and VEGF inhibitors].

  Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20100101

• Infliximab therapy increases body fat mass in early rheumatoid arthritis independently of changes in disease activity and levels of leptin and adiponectin: a randomised study over 21 months.

  Arthritis research & therapy 20100101

• [Guideline 'Diagnosis and treatment of inflammatory bowel disease in adults'. II. Special situations and organisation of medical care].

  Nederlands tijdschrift voor geneeskunde 20100101

• Metastatic gestational trophoblastic neoplasia complicated by tumor lysis syndrome, heart failure, and thyrotoxicosis: a case report.

  The Journal of reproductive medicine 20100101

• Methotrexate: from its introduction to non-oncologic therapeutics to anti-TNF-α.

  Clinical and experimental rheumatology 20100101

• How does methotrexate suppress inflammation?

  Clinical and experimental rheumatology 20100101

• Methotrexate transport mechanisms: the basis for targeted drug delivery and ß-folate-receptor-specific treatment.

  Clinical and experimental rheumatology 20100101

• Optimal administration and dosage of methotrexate.

  Clinical and experimental rheumatology 20100101

• Drug combinations with methotrexate to treat rheumatoid arthritis.

  Clinical and experimental rheumatology 20100101

• Efficacy of methotrexate in comparison to biologics in rheumatoid arthritis.

  Clinical and experimental rheumatology 20100101

• Underestimation of the efficacy, effectiveness, tolerability, and safety of weekly low-dose methotrexate in information presented to physicians and patients.

  Clinical and experimental rheumatology 20100101

• Use of methotrexate in young patients with respect to the reproductive system.

  Clinical and experimental rheumatology 20100101

• Folate supplementation during methotrexate therapy for rheumatoid arthritis.

  Clinical and experimental rheumatology 20100101

• Methotrexate use and alcohol.

  Clinical and experimental rheumatology 20100101

• Use of methotrexate in patients with inflammatory bowel diseases.

  Clinical and experimental rheumatology 20100101

• Efficacy of methotrexate in the treatment of a HLA-B27-positive Japanease patient with reactive arthritis.

  Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology 20100101

• Autoimmune dysfunction and subsequent renal insufficiency in a collegiate female athlete: a case report.

  Journal of athletic training 20100101

• Clinical utility of biochemical bone turnover markers in children and adolescents with osteosarcoma.

  Advances in medical sciences 20100101

• Methotrexate binding causes structural and functional changes in lung cystatin.

  Acta biochimica Polonica 20100101

• Validation of treatment efficacy of a computer-assisted program for breast cancer patients receiving postoperative adjuvant chemotherapy.

  Asian Pacific journal of cancer prevention : APJCP 20100101

• Psoriasis triggered by mefloquine.

  Skinmed 20100101

• Monitoring treatment response of childhood acute lymphocytic leukemia with certain molecular and biochemical markers.

  Journal of biochemical and molecular toxicology 20100101

• Formation of reactive oxygen and nitrogen species in the presence of pinosylvin - an analogue of resveratrol.

  Neuro endocrinology letters 20100101

• Carnosine inhibits degradation of hyaluronan induced by free radical processes in vitro and improves the redox imbalance in adjuvant arthritis in vivo.

  Neuro endocrinology letters 20100101

• Maternal influences on the transmission of leukocyte gene expression profiles in population samples from Brisbane, Australia.

  PloS one 20100101

• High-dose methotrexate in children with acute lymphoblastic leukemia: 7-hydroxymethotrexate systemic exposure and urinary concentrations at the steady state correlate well with those of methotrexate.

  Arzneimittel-Forschung 20100101

• Cancer chemotherapy: targeting folic acid synthesis.

  Cancer management and research 20100101

• [Long-term observations of children with acute lymphoblastic leukemia and high leukocytosis treated according to modified 'New York' protocols (1987-2003)].

  Przeglad lekarski 20100101

• Sequential methotrexate treatment with and estrogen and progestin in a retained adhesive placenta.

  Clinical and experimental obstetrics & gynecology 20100101

• [Active psoriatic arthritis during pregnancy: challenges and limitations of pharmacotherapy].

  Annales Academiae Medicae Stetinensis 20100101

• [Adverse effects of cyclosporin a observed in rheumatoid arthritis and psoriatic arthritis].

  Annales Academiae Medicae Stetinensis 20100101

• [Nodular changes in lungs in a patient with rheumatoid arthritis. Diagnostic and therapeutic difficulties. Case report].

  Annales Academiae Medicae Stetinensis 20100101

• [A case of the association of acute lymphoblastic lymphoma with active tuberculosis in the child: a Malian case].

  Le Mali medical 20100101

• Methotrexate supports in vivo selection of human embryonic stem cell derived-hematopoietic cells expressing dihydrofolate reductase.

  Bioengineered bugs 20100101

• [Allogeneic mesenchymal stromal cells in patients with ulcerative colitis: two years of observation].

  Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20100101

• Conservative management of placenta accreta in a multiparous woman.

  Journal of pregnancy 20100101

• Weight patterns in children with higher risk ALL: A report from the Children's Oncology Group (COG) for CCG 1961.

  Pediatric blood & cancer 20091215

• Conidiobolomycosis in relapsed acute lymphoblastic leukemia.

  Pediatric blood & cancer 20091215

• Increased vulnerability of the spinal cord to radiation or intrathecal chemotherapy during adolescence: A report from the Children's Oncology Group.

  Pediatric blood & cancer 20091215

• Comparison of neurocognitive functioning in children previously randomly assigned to intrathecal methotrexate compared with triple intrathecal therapy for the treatment of childhood acute lymphoblastic leukemia.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20091210

• Antiapoptotic and antioxidant effects of beta-carotene against methotrexate-induced testicular injury.

  Fertility and sterility 20091201

• Clinical efficacy and safety of abatacept in methotrexate-naive patients with early rheumatoid arthritis and poor prognostic factors.

  Annals of the rheumatic diseases 20091201

• Comparative effectiveness of tumour necrosis factor alpha inhibitors in combination with either methotrexate or leflunomide.

  Annals of the rheumatic diseases 20091201

• Peripheral neuropathy with infliximab therapy in inflammatory bowel disease.

  Inflammatory bowel diseases 20091201

• Interstitial pneumonitis associated with infliximab therapy without methotrexate treatment.

  Rheumatology international 20091201

• In-office magnetic resonance imaging to monitor responses to therapy in rheumatoid arthritis.

  Rheumatology international 20091201

• Improvement of functional ability in children with juvenile idiopathic arthritis by treatment with etanercept.

  Rheumatology international 20091201

• Amyopathic juvenile dermatomyositis: a case presentation.

  Joint, bone, spine : revue du rhumatisme 20091201

• Adenovirally mediated p53 overexpression diversely influence the cell cycle of HEp-2 and CAL 27 cell lines upon cisplatin and methotrexate treatment.

  Journal of cancer research and clinical oncology 20091201

• DV-ICE, intensive induction and early transplantation for adult patients with acute lymphoblastic leukemia: a phase II study.

  European journal of haematology 20091201

• Response to glucocorticoids and toxicity in childhood acute lymphoblastic leukemia: role of polymorphisms of genes involved in glucocorticoid response.

  Pediatric blood & cancer 20091201

• Contralateral testicular relapse after prophylactic radiation in a patient with primary testicular diffuse large B-cell lymphoma.

  European journal of haematology 20091201

• Intra-arterial infusion of chemotherapy in the treatment of penile cancer.

  Japanese journal of clinical oncology 20091201

• A phase I/II study of the safety and efficacy of the addition of sirolimus to tacrolimus/methotrexate graft versus host disease prophylaxis after allogeneic haematopoietic cell transplantation in paediatric acute lymphoblastic leukaemia (ALL).

  British journal of haematology 20091201

• [Health-economic assessment of combination therapy for rheumatoid arthritis with methotrexat and etanercept based on the TEMPO Study].

  Zeitschrift fur Rheumatologie 20091201

• Case series of multiple recurrent reactive keratoacanthomas developing at surgical margins.

  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20091201

• Gene-gene interactions in folate and adenosine biosynthesis pathways affect methotrexate efficacy and tolerability in rheumatoid arthritis.

  Pharmacogenetics and genomics 20091201

• Disease status at autologous stem cell transplantation and the cell of origin phenotype are important predictors of outcome in patients with neurologic (central nervous system) relapse of diffuse large B-cell lymphoma undergoing autologous stem cell transplantation.

  Leukemia & lymphoma 20091201

• Tacrolimus/Methotrexate versus cyclosporine/methotrexate as graft-versus-host disease prophylaxis in patients with severe aplastic anemia who received bone marrow transplantation from unrelated donors: results of matched pair analysis.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20091201

• A novel high-performance liquid chromatography/mass spectrometry method for improved selective and sensitive measurement of methotrexate polyglutamation status in human red blood cells.

  Rapid communications in mass spectrometry : RCM 20091201

• Effect of methotrexate administration on status of some essential trace elements and antioxidant enzymes in pregnant rats in late gestation.

  Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20091201

• Monitoring methotrexate toxicity in juvenile idiopathic arthritis.

  The Journal of rheumatology 20091201

• The effects of METhotrexate therapy on the physical capacity of patients with ISchemic heart failure: a randomized double-blind, placebo-controlled trial (METIS trial).

  Journal of cardiac failure 20091201

• Rapamycin versus methotrexate in early diffuse systemic sclerosis: results from a randomized, single-blind pilot study.

  Arthritis and rheumatism 20091201

• Cancer research: from folate antagonism to molecular targets.

  Best practice & research. Clinical haematology 20091201

• Methotrexate: can it be a choice for nasal polyposis in aspirin exacerbated respiratory disease?

  The Journal of asthma : official journal of the Association for the Care of Asthma 20091201

• Abcc2 (Mrp2), Abcc3 (Mrp3), and Abcg2 (Bcrp1) are the main determinants for rapid elimination of methotrexate and its toxic metabolite 7-hydroxymethotrexate in vivo.

  Molecular cancer therapeutics 20091201

• Translational modulation of proteins expressed from bicistronic vectors.

  Molecular imaging 20091201

• Serum factors that suppress cytotoxic effect of methotrexate.

  Experimental oncology 20091201

• Childhood psoriasis: often favorable outcome.

  Prescrire international 20091201

• Cutaneous T-cell lymphoma: a review of current therapies and the future therapeutic implications of chemokine biology.

  Journal of drugs in dermatology : JDD 20091201

• A chemometric analysis of ligand-induced changes in intrinsic fluorescence of folate binding protein indicates a link between altered conformational structure and physico-chemical characteristics.

  Applied spectroscopy 20091201

• Tumor-specific cytotoxicity and type of cell death induced by gefitinib in oral squamous cell carcinoma cell lines.

  Anticancer research 20091201

• Use of pegfilgrastim support on day 9 to maintain relative dose intensity of chemotherapy in breast cancer patients receiving a day 1 and 8 CMF regimen.

  Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20091201

• Primary intra-osseous liposarcoma of the femur: a case report.

  Journal of orthopaedic surgery (Hong Kong) 20091201

• [Significant changes of pharmacotherapy in gastroenterological rehabilitation of Crohn's disease].

  Die Rehabilitation 20091201

• A case of refractory vasculitic ulcers in a systemic lupus erythematosus patient responding to rituximab and hyperbaric oxygen therapy.

  International journal of rheumatic diseases 20091201

• Outcome and haemato-toxicity of two chemotherapy regimens for childhood non-Hodgkin's lymphoma in a Kenyan hospital.

  East African medical journal 20091201

• Randomized phase II/III trial assessing gemcitabine/ carboplatin and methotrexate/carboplatin/vinblastine in patients with advanced urothelial cancer 'unfit' for cisplatin-based chemotherapy: phase II--results of EORTC study 30986.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20091120

• Mechanism of chemoresistance mediated by miR-140 in human osteosarcoma and colon cancer cells.

  Oncogene 20091119

• Benefit of radiation boost after whole-breast radiotherapy.

  International journal of radiation oncology, biology, physics 20091115

• Direct injection liquid chromatography/positive ion electrospray ionization mass spectrometric quantification of methotrexate, folinic acid, folic acid and ondansetron in human serum.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20091115

• Combretastatin-like chalcones as inhibitors of microtubule polymerization. Part 1: synthesis and biological evaluation of antivascular activity.

  Bioorganic & medicinal chemistry 20091115

• DNA variants in region for noncoding interfering transcript of dihydrofolate reductase gene and outcome in childhood acute lymphoblastic leukemia.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20091115

• Severe 20-nail psoriasis successfully treated by low dose methotrexate.

  Dermatology online journal 20091115

• Inhibition of nucleoside transport and synergistic potentiation of methotrexate cytotoxicity by cimicifugoside, a triterpenoid from Cimicifuga simplex.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20091105

• Expression profiling identifies genes that predict recurrence of breast cancer after adjuvant CMF-based chemotherapy.

  Breast cancer research and treatment 20091101

• Subtle changes in individual joints result in both positive and negative change scores in a patient: results from a clinical trial in patients with rheumatoid arthritis.

  Annals of the rheumatic diseases 20091101

• The prognostic impact of occult nodal metastasis in early breast carcinoma.

  Breast cancer research and treatment 20091101

• Weekly intramuscular methotrexate in the treatment of low-risk gestational trophoblastic neoplasia.

  Archives of gynecology and obstetrics 20091101

• Additional chromosomal abnormalities and their prognostic significance in adult Philadelphia-positive acute lymphoblastic leukemia: with or without imatinib in chemotherapy.

  Annals of hematology 20091101

• Treatment outcome of adult patients with Burkitt lymphoma: results using the LMB protocol in Korea.

  Annals of hematology 20091101

• In vitro interactions between antifungals and methotrexate against Aspergillus spp.

  Mycopathologia 20091101

• High prevalence of retinoblastoma protein loss in triple-negative breast cancers and its association with a good prognosis in patients treated with adjuvant chemotherapy.

  Annals of oncology : official journal of the European Society for Medical Oncology 20091101

• Swelling properties of copolymeric hydrogels of poly(ethylene glycol) monomethacrylate and monoesters of itaconic acid for use in drug delivery.

  Journal of biomedical materials research. Part B, Applied biomaterials 20091101

• Unusual cervical spine involvement in psoriatic arthritis: a case series.

  Clinical rheumatology 20091101

• Dofequidar fumarate sensitizes cancer stem-like side population cells to chemotherapeutic drugs by inhibiting ABCG2/BCRP-mediated drug export.

  Cancer science 20091101

• Differential usage of the transport systems for folic acid and methotrexate in normal human T-lymphocytes and leukemic cells.

  Journal of biochemistry 20091101

• Successful treatment of severe or methotrexate-resistant juvenile localized scleroderma with mycophenolate mofetil.

  Rheumatology (Oxford, England) 20091101

• Disease-modifying treatment in systemic sclerosis: current status.

  Current opinion in rheumatology 20091101

• High dose methotrexate population pharmacokinetics and Bayesian estimation in patients with lymphoid malignancy.

  Biopharmaceutics & drug disposition 20091101

• Methotrexate for ocular inflammatory diseases.

  Ophthalmology 20091101

• Cyclophosphamide, doxorubicin, vincristine, methotrexate, bleomicin and prednisone plus rituximab in untreated young patients with low-risk (age-adjusted international prognostic index 0-1) diffuse large B-cell lymphoma.

  Leukemia & lymphoma 20091101

• Genoproteomic mining of urothelial cancer suggests {gamma}-glutamyl hydrolase and diazepam-binding inhibitor as putative urinary markers of outcome after chemotherapy.

  The American journal of pathology 20091101

• Improved nonrelapse mortality and infection rate with lower dose of antithymocyte globulin in patients undergoing reduced-intensity conditioning allogeneic transplantation for hematologic malignancies.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20091101

• Studies on in vitro and in vivo transdermal flux enhancement of methotrexate by a combinational approach in comparison to oral delivery.

  Drug development and industrial pharmacy 20091101

• [Methotrexate in rheumatology].

  Zeitschrift fur Rheumatologie 20091101

• Random serum methotrexate determinations for assessing compliance with maintenance therapy for childhood acute lymphoblastic leukemia.

  Leukemia & lymphoma 20091101

• QuantiFERON-TB Gold in the identification of latent tuberculosis infection in rheumatoid arthritis: a pilot study.

  The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20091101

• Positron emission tomography guided therapy of aggressive non-Hodgkin lymphomas--the PETAL trial.

  Leukemia & lymphoma 20091101

• [Cutaneous infection due to Mycobacterium chelonae during anti-TNF therapy].

  Annales de dermatologie et de venereologie 20091101

• Doxorubicin and cyclophosphamide versus cyclophosphamide, methotrexate, and 5-fluorouracil as adjuvant chemotherapy in breast cancer.

  Journal of chemotherapy (Florence, Italy) 20091101

• Acute renal failure after high-dose methotrexate therapy in a patient with ileostomy.

  [Rinsho ketsueki] The Japanese journal of clinical hematology 20091101

• The cytotoxic effects of gemtuzumab ozogamicin (mylotarg) in combination with conventional antileukemic agents by isobologram analysis in vitro.

  Anticancer research 20091101

• High-dose cytarabine plus high-dose methotrexate versus high-dose methotrexate alone in patients with primary CNS lymphoma: a randomised phase 2 trial.

  Lancet (London, England) 20091031

• Progress in primary CNS lymphoma.

  Lancet (London, England) 20091031

• Determination of methotrexate in human serum by high-performance liquid chromatography combined with pseudo template molecularly imprinted polymer.

  Journal of chromatography. A 20091030

• Bortezomib, tacrolimus, and methotrexate for prophylaxis of graft-versus-host disease after reduced-intensity conditioning allogeneic stem cell transplantation from HLA-mismatched unrelated donors.

  Blood 20091029

• Host-guest chemistry of dendrimer-drug complexes. 3. Competitive binding of multiple drugs by a single dendrimer for combination therapy.

  The journal of physical chemistry. B 20091029

• Myeloperoxidase genotypes and enhanced efficacy of chemotherapy for early-stage breast cancer in SWOG-8897.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20091020

• [Therapeutic management of central nervous system lymphomas in a single hematological institute].

  Orvosi hetilap 20091018

• Expression of eukaryotic initiation factor 4E predicts clinical outcome in patients with mantle cell lymphoma treated with hyper-CVAD and rituximab, alternating with rituximab, high-dose methotrexate, and cytarabine.

  Cancer 20091015

• Design, synthesis, and X-ray crystal structures of 2,4-diaminofuro[2,3-d]pyrimidines as multireceptor tyrosine kinase and dihydrofolate reductase inhibitors.

  Bioorganic & medicinal chemistry 20091015

• Critical role for tetrahydrobiopterin recycling by dihydrofolate reductase in regulation of endothelial nitric-oxide synthase coupling: relative importance of the de novo biopterin synthesis versus salvage pathways.

  The Journal of biological chemistry 20091009

• WITHDRAWN: Immunosuppressant and immunomodulatory treatment for dermatomyositis and polymyositis.

  The Cochrane database of systematic reviews 20091007

• Methotrexate for maintenance of remission in Crohn's disease.

  The Cochrane database of systematic reviews 20091007

• The efficacy and safety of concurrent chemoradiotherapy for maxillary sinus squamous cell carcinoma patients.

  Auris, nasus, larynx 20091001

• Enhanced permeation of methotrexate in vitro by ion pair formation with L-arginine.

  Journal of pharmaceutical sciences 20091001

• Adjuvant goserelin and ovarian preservation in chemotherapy treated patients with early breast cancer: results from a randomized trial.

  Breast cancer research and treatment 20091001

• Distinct mechanistic activity profile of pralatrexate in comparison to other antifolates in in vitro and in vivo models of human cancers.

  Cancer chemotherapy and pharmacology 20091001

• Relapse-remission and remission-relapse switches in rheumatoid arthritis patients were modeled by random effects.

  Journal of clinical epidemiology 20091001

• Serum homocysteine level in patients with ankylosing spondylitis.

  Rheumatology international 20091001

• Marked hypertriglyceridemia upon treatment with etanercept.

  Joint, bone, spine : revue du rhumatisme 20091001

• Reduced libido and erectile dysfunction: rarely reported side-effects of methotrexate.

  Clinical and experimental dermatology 20091001

• The race and dose of chemotherapy should be considered for optimizing maintenance therapy for acute promyelocytic leukemia.

  Leukemia research 20091001

• Salazosulfapyridine-induced hypersensitivity syndrome triggered by methotrexate.

  Clinical and experimental dermatology 20091001

• Methotrexate is effective in reactivated colitis and reduces inflammatory alterations in mesenteric adipose tissue during intestinal inflammation.

  Pharmacological research 20091001

• Methotrexate with or without misoprostol to terminate pregnancies with no gestational sac visible by ultrasound.

  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20091001

• Long-term efficacy of mycophenolate mofetil in a case of refractory antisynthetase syndrome.

  Joint, bone, spine : revue du rhumatisme 20091001

• The critical role of alpha-folate receptor in the resistance of melanoma to methotrexate.

  Pigment cell & melanoma research 20091001

• Does TNF-alpha blockade play any role in cardiovascular risk among rheumatoid arthritis (RA) patients?

  Clinical rheumatology 20091001

• Methotrexate and aminopterin lack in vivo antimalarial activity against murine malaria species.

  Experimental parasitology 20091001

• Adverse events associated with common therapy regimens for moderate-to-severe Crohn's disease.

  The American journal of gastroenterology 20091001

• Physiological and molecular characterization of methotrexate transport by Malpighian tubules of adult Drosophila melanogaster.

  Journal of insect physiology 20091001

• Species-specific differences in translational regulation of dihydrofolate reductase.

  Molecular pharmacology 20091001

• Methotrexate-induced apoptosis is enhanced by altered expression of methylenetetrahydrofolate reductase.

  Anti-cancer drugs 20091001

• Efficacy of SLZ and MTX (alone or combination) on the treatment of active sacroiliitis in early AS.

  Rheumatology international 20091001

• Examination of the effects of methotrexate on histological and steroid receptor changes in the endosalpinx of the rat.

  European journal of obstetrics, gynecology, and reproductive biology 20091001

• Regression of chronic posterior leukoencephalopathy after stop of methotrexate treatment.

  Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20091001

• Impact of trough serum level on radiographic and clinical response to infliximab plus methotrexate in patients with rheumatoid arthritis: results from the RISING study.

  Modern rheumatology 20091001

• The acute effects of CMF-based chemotherapy on maxillary periodontal microcirculation.

  Cancer chemotherapy and pharmacology 20091001

• Methotrexate therapy in rheumatoid arthritis after failure to sulphasalazine: to switch or to add?

  Rheumatology (Oxford, England) 20091001

• Incidence and outcome of patients with diffuse large B cell lymphoma with marrow involvement and preliminary experience of an adult acute lymphoblastic leukemia protocol (NEALL VI) in cyclophosphamide, doxorubicin, vincristine, and prednisolone--rituximab refractory patients.

  Leukemia & lymphoma 20091001

• Gene polymorphisms in folate metabolizing enzymes in adult acute lymphoblastic leukemia: effects on methotrexate-related toxicity and survival.

  Haematologica 20091001

• Changes in matrix metalloproteinase (MMP) and tissue inhibitors of metalloproteinases (TIMP) expression profile in Crohn's disease after immunosuppressive treatment correlate with histological score and calprotectin values.

  International journal of colorectal disease 20091001

• The effect of active hexose correlated compound in modulating cytosine arabinoside-induced hair loss, and 6-mercaptopurine- and methotrexate-induced liver injury in rodents.

  Cancer epidemiology 20091001

• Urinary metabolic profile of phenylketonuria in patients receiving total parenteral nutrition and medication.

  Rapid communications in mass spectrometry : RCM 20091001

• Sirolimus-containing graft-versus-host disease prophylaxis in patients with lymphoma.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20091001

• Identification of NR4A2 as a transcriptional activator of IL-8 expression in human inflammatory arthritis.

  Molecular immunology 20091001

• Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.

  Bioorganic & medicinal chemistry 20091001

• Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

  Nature chemical biology 20091001

• Acute methotrexate neurotoxicity with choreiform movements and focal neurological deficits: a case report.

  Southern medical journal 20091001

• Emerging treatments in cystic fibrosis.

  Drugs 20091001

• CXCL13 and CXCL12 in central nervous system lymphoma patients.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20091001

• Examination of the effect of increasing doses of etoricoxib on oral methotrexate pharmacokinetics in patients with rheumatoid arthritis.

  Journal of clinical pharmacology 20091001

• Chemotherapy: Adjuvant chemotherapy in older patients with breast cancer.

  Nature reviews. Clinical oncology 20091001

• Normalization of A2A and A3 adenosine receptor up-regulation in rheumatoid arthritis patients by treatment with anti-tumor necrosis factor alpha but not methotrexate.

  Arthritis and rheumatism 20091001

• [Progress in chemotherapy for advanced gastric cancer].

  Ai zheng = Aizheng = Chinese journal of cancer 20091001

• Meningeal dissemination from an ovarian carcinoma with effective response to intrathecal chemotherapy.

  International journal of clinical oncology 20091001

• Placental site trophoblastic tumor (PSTT) with multiple metastases and extremely poor prognosis.

  International journal of clinical oncology 20091001

• Rituximab combined with MACOP-B or VACOP-B and radiation therapy in primary mediastinal large B-cell lymphoma: a retrospective study.

  Clinical lymphoma & myeloma 20091001

• Nontuberculous mycobacteria infection and tumor necrosis factor-alpha antagonists.

  Emerging infectious diseases 20091001

• Multicentric plasmocytic Castleman's disease with polyneuropathy, organomegaly, endocrinopathy, M protein, skin changes syndrome and coexistent human herpes virus-6 infection--a possible relationship.

  Leukemia & lymphoma 20091001

• Drug-induced photosensitivity.

  Prescrire international 20091001

• [Medical management of primary central nervous system lymphoma refractory or resistant to standard of care treatment].

  Brain and nerve = Shinkei kenkyu no shinpo 20091001

• Concurrent langerhans cell histiocytosis and B-lineage lymphoid proliferation in the bone marrow.

  The Korean journal of laboratory medicine 20091001

• Purine biosynthetic pathway genes and methotrexate response in rheumatoid arthritis patients among north Indians.

  Pharmacogenetics and genomics 20091001

• [Clinical impact of extracapsular extension of axillary lymph node metastases in breast cancer].

  Zhonghua zhong liu za zhi [Chinese journal of oncology] 20091001

• A novel methotrexate delivery system based on chitosan-methotrexate covalently conjugated nanoparticles.

  Journal of biomedical nanotechnology 20091001

• Effects of putative catalytic base mutation E211Q on ABCG2-mediated methotrexate transport.

  Biochemistry 20090929

• Expression of multidrug resistance proteins in prostate cancer is related with cell sensitivity to chemotherapeutic drugs.

  The Prostate 20090915

• Efficacy of methotrexate in Crohn's disease and ulcerative colitis patients unresponsive or intolerant to azathioprine /mercaptopurine.

  Alimentary pharmacology & therapeutics 20090915

• Polar anionic metabolome analysis by nano-LC/MS with a metal chelating agent.

  Analytical chemistry 20090915

• Images in clinical medicine. Baker's cyst in a patient with rheumatoid arthritis.

  The New England journal of medicine 20090910

• Chemoradiotherapy for locally advanced head and neck cancer: 10-year follow-up of the UK Head and Neck (UKHAN1) trial.

  The Lancet. Oncology 20090909

• Simultaneous determination of methotrexate and its polyglutamate metabolites in Caco-2 cells by liquid chromatography-tandem mass spectrometry.

  Journal of pharmaceutical and biomedical analysis 20090908

• Adding low dose tacrolimus in rheumatoid arthritis patients with an inadequate response to tumor necrosis factor inhibitor therapies.

  Rheumatology international 20090901

• Clinical expression of leflunomide-induced pneumonitis.

  Rheumatology (Oxford, England) 20090901

• Steroid refractory CD4+ T cells in patients with sight-threatening uveitis.

  Investigative ophthalmology & visual science 20090901

• A 24-year-old pregnant woman with inflammatory bowel disease.

  Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20090901

• Lack of TIMP-1 tumour cell immunoreactivity predicts effect of adjuvant anthracycline-based chemotherapy in patients (n=647) with primary breast cancer. A Danish Breast Cancer Cooperative Group Study.

  European journal of cancer (Oxford, England : 1990) 20090901

• Lymphocyte transformation test is not helpful for the diagnosis of methotrexate-induced pneumonitis in patients with rheumatoid arthritis.

  Clinica chimica acta; international journal of clinical chemistry 20090901

• Primary central nervous system lymphoma: recent progress, many remaining questions.

  Current opinion in oncology 20090901

• [Carboxypeptidase-G2 administration after high-dose methotrexate. Treatment and drug interactions].

  Anales de pediatria (Barcelona, Spain : 2003) 20090901

• Ozone ameliorates methotrexate-induced intestinal injury in rats.

  Cancer biology & therapy 20090901

• Dermatomyositis with inclusion body myositis pathology.

  Muscle & nerve 20090901

• An osteoporotic hip fracture in a 14-year-old girl undergoing chemotherapy and operated for knee osteosarcoma.

  Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology 20090901

• Tissue inhibitor metalloproteinase type-1 (TIMP-1), a novel cancer biomarker predicting response of adjuvant anthracycline-based chemotherapy in patients afflicted with primary breast cancer.

  European journal of cancer (Oxford, England : 1990) 20090901

• Mesial temporal sclerosis after posterior reversible encephalopathy syndrome.

  Pediatric neurology 20090901

• Anaplastic large cell lymphoma of the ovary in a pediatric patient.

  Journal of pediatric hematology/oncology 20090901

• Standard graft-versus-host disease prophylaxis with or without anti-T-cell globulin in haematopoietic cell transplantation from matched unrelated donors: a randomised, open-label, multicentre phase 3 trial.

  The Lancet. Oncology 20090901

• [Chronic lymphocytic leukemia in Subsaharian Africa: clinical outcome experience of Côte d'Ivoire].

  Bulletin du cancer 20090901

• Adjuvant chemotherapy for older adults with breast cancer: making the standard a standard.

  Women's health (London, England) 20090901

• [Rheumatoid arthritis].

  Deutsche medizinische Wochenschrift (1946) 20090901

• Ocular findings after allogeneic hematopoietic stem cell transplantation.

  Ophthalmology 20090901

• Cost analysis comparing an anthracycline/docetaxel regimen to CMF in patients with early stage breast cancer.

  Onkologie 20090901

• Absence of transaminase elevation during concomitant methotrexate and isoniazid therapy.

  The Journal of rheumatology 20090901

• [Chemotherapy with MTX, 5-FU and CDGP for treatment of newly diagnosed head and neck cancer].

  Gan to kagaku ryoho. Cancer & chemotherapy 20090901

• Treatment of rat adjuvant arthritis with flavonoid (Detralex), methotrexate, and their combination.

  Annals of the New York Academy of Sciences 20090901

• A case of primary intraocular lymphoma treated by intravitreal methotrexate.

  Korean journal of ophthalmology : KJO 20090901

• Characterization of solvatomorphs of methotrexate using thermoanalytical and other techniques.

  Acta pharmaceutica (Zagreb, Croatia) 20090901

• Gallbladder squamous cell carcinoma in the setting of low-dose methotrexate use.

  ANZ journal of surgery 20090901

• Metastasis of gestational trophoblastic neoplasia to the spinal canal: a case report.

  The Journal of reproductive medicine 20090901

• [Effects of wenhua juanbi recipe on TNF-alpha and IL-1beta in peripheral blood of rheumatoid arthritis patients].

  Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20090901

• Converting cancer mutations into therapeutic opportunities.

  EMBO molecular medicine 20090901

• Methotrexate induces oxidative DNA damage and is selectively lethal to tumour cells with defects in the DNA mismatch repair gene MSH2.

  EMBO molecular medicine 20090901

• Methotrexate delivery via folate targeted dendrimer-based nanotherapeutic platform.

  Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology 20090901

• Response: Intrathecal methotrexate and central nervous system events.

  Blood 20090827

• Intrathecal MTX for DLBCL: from an inappropriate prophylactic tradition to a medical error?

  Blood 20090827

• Uracil-tegafur and tamoxifen vs cyclophosphamide, methotrexate, fluorouracil, and tamoxifen in post-operative adjuvant therapy for stage I, II, or IIIA lymph node-positive breast cancer: a comparative study.

  British journal of cancer 20090818

• Nitric oxide synthase variants and disease-free survival among treated and untreated breast cancer patients in a Southwest Oncology Group clinical trial.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20090815

• Differential methotrexate hepatotoxicity on rat hepatocytes in 2-D monolayer culture and 3-D gel entrapment culture.

  Chemico-biological interactions 20090814

• Polymorphisms in multidrug resistance-associated protein gene 4 is associated with outcome in childhood acute lymphoblastic leukemia.

  Blood 20090813

• A relapse of systemic type juvenile idiopathic arthritis after a rubella vaccination in a patient during a long-term remission period.

  Vaccine 20090813

• Design, synthesis, and X-ray crystal structure of classical and nonclassical 2-amino-4-oxo-5-substituted-6-ethylthieno[2,3-d]pyrimidines as dual thymidylate synthase and dihydrofolate reductase inhibitors and as potential antitumor agents.

  Journal of medicinal chemistry 20090813

• [Disease-modifying anti-rheumatic drugs for treatment of ankylosing spondylitis].

  Ugeskrift for laeger 20090810

• Addition of infliximab compared with addition of sulfasalazine and hydroxychloroquine to methotrexate in patients with early rheumatoid arthritis (Swefot trial): 1-year results of a randomised trial.

  Lancet (London, England) 20090808

• Effect of methotrexate exposure on subsequent fertility in women undergoing controlled ovarian stimulation.

  Fertility and sterility 20090801

• Is adjuvant chemotherapy of benefit for postmenopausal women who receive endocrine treatment for highly endocrine-responsive, node-positive breast cancer? International Breast Cancer Study Group Trials VII and 12-93.

  Breast cancer research and treatment 20090801

• Predicting factors of fistula healing and clinical remission after infliximab-based combined therapy for perianal fistulizing Crohn's disease.

  Digestive diseases and sciences 20090801

• Effect of ursodeoxycholic acid treatment on the expression and function of multidrug resistance-associated protein 2 in rat intestine.

  Journal of pharmaceutical sciences 20090801

• Methotrexate treatment ameliorated testicular suppression and anorexia related leptin reduction in rats with adjuvant arthritis.

  Rheumatology international 20090801

• Comparison of enteroprotective efficacy of triphala formulations (Indian Herbal Drug) on methotrexate-induced small intestinal damage in rats.

  Phytotherapy research : PTR 20090801

• Folinic acid administration following MTX as prophylaxis for GVHD.

  Bone marrow transplantation 20090801

• Reversal of neurological deficit after chemotherapy in BCL-6-positive neurolymphomatosis. Case report.

  Journal of neurosurgery 20090801

• Intra-articular treatment of inflammatory arthritis with microsphere formulations of methotrexate: pharmacokinetics and efficacy determination in antigen-induced arthritic rabbits.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20090801

• Posterior reversible encephalopathy syndrome associated with methotrexate neurotoxicity: conventional magnetic resonance and diffusion-weighted imaging findings.

  Journal of child neurology 20090801

• t(3;9;22) 3-way chromosome translocation in chronic myeloid leukemia is associated with poor prognosis.

  Cancer investigation 20090801

• Role of the sodium hydrogen exchanger in maitotoxin-induced cell death in cultured rat cortical neurons.

  Toxicon : official journal of the International Society on Toxinology 20090801

• A new low-field extremity magnetic resonance imaging and proposed compact MRI score: evaluation of anti-tumor necrosis factor biologics on rheumatoid arthritis.

  Modern rheumatology 20090801

• Efficacy of an Andrographis paniculata composition for the relief of rheumatoid arthritis symptoms: a prospective randomized placebo-controlled trial.

  Clinical rheumatology 20090801

• Complex pharmacokinetic behavior of ezetimibe depends on abcc2, abcc3, and abcg2.

  Drug metabolism and disposition: the biological fate of chemicals 20090801

• A systematic MEDLINE analysis of therapeutic approaches in ankylosing spondylitis.

  Rheumatology international 20090801

• Autologous and allogeneic stem cell transplantation: rising therapeutic promise for mantle cell lymphoma.

  Leukemia & lymphoma 20090801

• Folate overproduction in Lactobacillus plantarum WCFS1 causes methotrexate resistance.

  FEMS microbiology letters 20090801

• Optimalization of the clinical pharmacogenetic model to predict methotrexate treatment response: the influence of the number of haplotypes of MTHFR 1298A-677C alleles on probability to respond.

  Annals of the rheumatic diseases 20090801

• Ectopic pregnancy following levonorgestrel emergency contraception.

  Contraception 20090801

• Determinants of red blood cell methotrexate polyglutamate concentrations in rheumatoid arthritis patients receiving long-term methotrexate treatment.

  Arthritis and rheumatism 20090801

• Methotrexate catabolism to 7-hydroxymethotrexate in rheumatoid arthritis alters drug efficacy and retention and is reduced by folic acid supplementation.

  Arthritis and rheumatism 20090801

• Erythrocyte methotrexate-polyglutamate assay using fluorescence polarization immunoassay technique: application to the monitoring of patients with rheumatoid arthritis.

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20090801

• Gingival crevicular fluid MMP-8 and -13 and TIMP-1 levels in patients with rheumatoid arthritis and inflammatory periodontal disease.

  Journal of periodontology 20090801

• Methionine restriction reduces the chemosensitivity of central nervous system tumour cell lines.

  Anticancer research 20090801

• Sarcoidal anemia and leukopenia treated with methotrexate and mycophenolate mofetil.

  Archives of dermatology 20090801

• Purely intramedullary spinal cord primitive neuroectodermal tumor: case report and review of the literature.

  Neurocirugia (Asturias, Spain) 20090801

• Potential predisposition for nasal septal perforation with methotrexate use: report of 2 cases and literature review.

  Ear, nose, & throat journal 20090801

• Prevention of neurotoxicity by high-dose folinic acid rescue after high-dose methotrexate and intrathecal methotrexate without compromising cure inspite of previous transient leukoencephalopathy after intrathecal methotrexate.

  Annals of the Academy of Medicine, Singapore 20090801

• Multiple conformers in active site of human dihydrofolate reductase F31R/Q35E double mutant suggest structural basis for methotrexate resistance.

  The Journal of biological chemistry 20090724

• A new generalization of Weibull distribution with application to a breast cancer data set.

  Statistics in medicine 20090720

• Golimumab in patients with active rheumatoid arthritis after treatment with tumour necrosis factor alpha inhibitors (GO-AFTER study): a multicentre, randomised, double-blind, placebo-controlled, phase III trial.

  Lancet (London, England) 20090718

• Development of enzymatically cleavable prodrugs derived from dendritic polyglycerol.

  Bioorganic & medicinal chemistry letters 20090715

• Interventions for previously untreated patients with AIDS-associated non-Hodgkin's lymphoma.

  The Cochrane database of systematic reviews 20090708

• Methotrexate for maintenance of remission in ulcerative colitis.

  The Cochrane database of systematic reviews 20090708

• Prognostic markers and long-term outcome of placental-site trophoblastic tumours: a retrospective observational study.

  Lancet (London, England) 20090704

• Visceral leishmaniasis in a rheumatoid arthritis patient treated with methotrexate.

  International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20090701

• Efficacy of continuous venovenous hemofiltration with chemotherapy in patients with Burkitt lymphoma and leukemia at high risk of tumor lysis syndrome.

  Annals of hematology 20090701

• Optimal dosage and route of administration of methotrexate in rheumatoid arthritis: a systematic review of the literature.

  Annals of the rheumatic diseases 20090701

• Multinational evidence-based recommendations for the use of methotrexate in rheumatic disorders with a focus on rheumatoid arthritis: integrating systematic literature research and expert opinion of a broad international panel of rheumatologists in the 3E Initiative.

  Annals of the rheumatic diseases 20090701

• Efficacy and toxicity of methotrexate (MTX) monotherapy versus MTX combination therapy with non-biological disease-modifying antirheumatic drugs in rheumatoid arthritis: a systematic review and meta-analysis.

  Annals of the rheumatic diseases 20090701

• Long-term safety of methotrexate monotherapy in patients with rheumatoid arthritis: a systematic literature research.

  Annals of the rheumatic diseases 20090701

• White matter fractional anisotropy correlates with speed of processing and motor speed in young childhood cancer survivors.

  International journal of radiation oncology, biology, physics 20090701

• Primary CNS lymphoma presenting as fever of unknown origin.

  Journal of neuro-oncology 20090701

• The up-regulation of monocyte chemoattractant protein-1 (MCP-1) in Ea.hy 926 endothelial cells under long-term low folate stress is mediated by the p38 MAPK pathway.

  Atherosclerosis 20090701

• Epithelioid osteosarcoma of the jaw.

  Pediatric blood & cancer 20090701

• NC-1059: a channel-forming peptide that modulates drug delivery across in vitro corneal epithelium.

  Investigative ophthalmology & visual science 20090701

• Antitumor therapy based on cellular competition.

  Human gene therapy 20090701

• [Cutaneous leishmaniasis in rheumatoid arthritis].

  La Revue de medecine interne 20090701

• Advances in the pathogenesis and treatment of IBD.

  Clinical immunology (Orlando, Fla.) 20090701

• False-photosensitivity and transient hemiparesis following high-dose intravenous and intrathecal methotrexate for treatment of acute lymphoblastic leukemia.

  Pediatric blood & cancer 20090701

• Malnutrition and neutropenia in children treated for Burkitt lymphoma in Malawi.

  Pediatric blood & cancer 20090701

• Methotrexate-associated alterations of the folate and methyl-transfer pathway in the CSF of ALL patients with and without symptoms of neurotoxicity.

  Pediatric blood & cancer 20090701

• Protective effects of amifostine and cyclooxygenase-1 inhibitor against normal human epidermal keratinocyte toxicity induced by methotrexate and 5-fluorouracil.

  Basic & clinical pharmacology & toxicology 20090701

• Role of the glutamate 185 residue in proton translocation mediated by the proton-coupled folate transporter SLC46A1.

  American journal of physiology. Cell physiology 20090701

• Haemolytic anaemia following rituximab treatment in a patient with pemphigus vulgaris.

  The British journal of dermatology 20090701

• [Anti-CD20 therapy in rheumatoid arthritis].

  Zeitschrift fur Rheumatologie 20090701

• Methotrexate in combination with sulfasalazine is more effective in rheumatoid arthritis patients who failed sulfasalazine than in patients naive to both drugs.

  Rheumatology (Oxford, England) 20090701

• A retrospective analysis of treatment responses of palmoplantar psoriasis in 114 patients.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20090701

• Facilitating the use of COBRA combination therapy in early rheumatoid arthritis: a pilot implementation study.

  The Journal of rheumatology 20090701

• Management of RA medications in pregnant patients.

  Nature reviews. Rheumatology 20090701

• Haematodermic CD4+CD56+ neoplasm: complete remission after methotrexate-asparaginase treatment.

  Clinical and experimental dermatology 20090701

• A novel method to prepare magnetite chitosan microspheres conjugated with methotrexate (MTX) for the controlled release of MTX as a magnetic targeting drug delivery system.

  Drug delivery 20090701

• Comparison of Tacrolimus and Sirolimus (Tac/Sir) versus Tacrolimus, Sirolimus, and mini-methotrexate (Tac/Sir/MTX) as acute graft-versus-host disease prophylaxis after reduced-intensity conditioning allogeneic peripheral blood stem cell transplantation.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20090701

• A retrospective study to compare two methotrexate-based regimens for primary central nervous system lymphoma.

  Leukemia & lymphoma 20090701

• Structures of dihydrofolate reductase-thymidylate synthase of Trypanosoma cruzi in the folate-free state and in complex with two antifolate drugs, trimetrexate and methotrexate.

  Acta crystallographica. Section D, Biological crystallography 20090701

• Gene expression signatures in polyarticular juvenile idiopathic arthritis demonstrate disease heterogeneity and offer a molecular classification of disease subsets.

  Arthritis and rheumatism 20090701

• Preliminary study to identify the predictive factors for the response to methotrexate therapy in patients with rheumatoid arthritis.

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20090701

• Actinomycin d versus methotrexate-folinic acid as the treatment of stage I, low-risk gestational trophoblastic neoplasia: a randomized controlled trial.

  International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20090701

• Site-specific contribution of proton-coupled folate transporter/haem carrier protein 1 in the intestinal absorption of methotrexate in rats.

  The Journal of pharmacy and pharmacology 20090701

• Monoketocholate can decrease transcellular permeation of methotrexate across Caco-2 cell monolayers and reduce its intestinal absorption in rat.

  The Journal of pharmacy and pharmacology 20090701

• [Prophylaxis and treatment of modified BFM-90 regimen for lymphoblastic lymphoma in children and adolescents accompanied with infection].

  Ai zheng = Aizheng = Chinese journal of cancer 20090701

• Pediatric inflammatory bowel disease in South India.

  Indian pediatrics 20090701

• Retention rates of disease-modifying anti-rheumatic drugs in patients with rheumatoid arthritis.

  Singapore medical journal 20090701

• [Plasmacytoid urothelial carcinoma of the bladder: a case report].

  Nihon Hinyokika Gakkai zasshi. The japanese journal of urology 20090701

• Systemic therapies for pediatric atopic dermatitis: a review for the primary care physician.

  Pediatric annals 20090701

• Polymorphisms in methotrexate pathways: what is clinically relevant, what is not, and what is promising.

  Current drug metabolism 20090701

• [A clinical study of leflunomide and methotrexate therapy in psoriatic arthritis].

  Zhonghua nei ke za zhi 20090701

• Sensitization of ABCG2-overexpressing cells to conventional chemotherapeutic agent by sunitinib was associated with inhibiting the function of ABCG2.

  Cancer letters 20090628

• Treating childhood acute lymphoblastic leukemia without cranial irradiation.

  The New England journal of medicine 20090625

• [Toxic effects on the lung: is 'pneumonia' caused by drugs?].

  MMW Fortschritte der Medizin 20090625

• Methotrexate induces apoptosis in CaSki and NRK cells and influences the organization of their actin cytoskeleton.

  European journal of pharmacology 20090624

• Prognostic significance of CD20 expression in adults with de novo precursor B-lineage acute lymphoblastic leukemia.

  Blood 20090618

• New insights into the interactions between dendrimers and surfactants: 2. Design of new drug formulations based on dendrimer-surfactant aggregates.

  The journal of physical chemistry. B 20090618

• Chemo-enzymatic synthesis of degradable PTMC-b-PECA-b-PTMC triblock copolymers and their micelle formation for pH-dependent controlled release.

  Macromolecular bioscience 20090611

• Methotrexate/6-mercaptopurine maintenance therapy influences the risk of a second malignant neoplasm after childhood acute lymphoblastic leukemia: results from the NOPHO ALL-92 study.

  Blood 20090611

• On the malignant potential of thiopurine therapy.

  Blood 20090611

• Drug-free remission, functioning and radiographic damage after 4 years of response-driven treatment in patients with recent-onset rheumatoid arthritis.

  Annals of the rheumatic diseases 20090601

• Exploring dendrimer towards dual drug delivery: pH responsive simultaneous drug-release kinetics.

  Journal of microencapsulation 20090601

• Providing patients with information about disease-modifying anti-rheumatic drugs: Individually or in groups? A pilot randomized controlled trial comparing adherence and satisfaction.

  Musculoskeletal care 20090601

• Efficacy and safety of certolizumab pegol plus methotrexate in active rheumatoid arthritis: the RAPID 2 study. A randomised controlled trial.

  Annals of the rheumatic diseases 20090601

• Golimumab, a human antibody to tumour necrosis factor {alpha} given by monthly subcutaneous injections, in active rheumatoid arthritis despite methotrexate therapy: the GO-FORWARD Study.

  Annals of the rheumatic diseases 20090601

• Liposomal cytarabine in cerebrospinal fluid.

  British journal of haematology 20090601

• Effect of lipid core material on characteristics of solid lipid nanoparticles designed for oral lymphatic delivery.

  Nanomedicine : nanotechnology, biology, and medicine 20090601

• Economic evaluation of systemic therapies for moderate to severe psoriasis.

  The British journal of dermatology 20090601

• Recent advances in the treatment of systemic sclerosis.

  Clinical reviews in allergy & immunology 20090601

• Investigation of candidate polymorphisms and disease activity in rheumatoid arthritis patients on methotrexate.

  Rheumatology (Oxford, England) 20090601

• Effective treatment of advanced-stage childhood lymphoblastic lymphoma without prophylactic cranial irradiation: results of St Jude NHL13 study.

  Leukemia 20090601

• Antiepileptic drugs reduce efficacy of methotrexate chemotherapy by downregulation of Reduced folate carrier transport activity.

  Leukemia 20090601

• Neoplastic meningitis from breast carcinoma with complete response to liposomal cytarabine: case report.

  Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20090601

• Successful treatment of human metapneumovirus pneumonia using combination therapy with intravenous ribavirin and immune globulin.

  British journal of haematology 20090601

• Treatments for psoriasis and the risk of malignancy.

  Journal of the American Academy of Dermatology 20090601

• Methylenetetrahydrofolate reductase C677T and A1298C gene polymorphisms and therapy-related toxicity in children treated for acute lymphoblastic leukemia and non-Hodgkin lymphoma.

  Leukemia & lymphoma 20090601

• Use of serum progesterone measurements to reduce need for follow-up in women with pregnancies of unknown location.

  Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 20090601

• Successful prevention of acute graft-versus-host disease using low-dose antithymocyte globulin after mismatched, unrelated, hematopoietic stem cell transplantation for acute myelogenous leukemia.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20090601

• Longitudinal assessment of morbidity and acute graft-versus-host disease after allogeneic hematopoietic cell transplantation: retrospective analysis of a multicenter phase III study.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20090601

• [Prolonged fever and monocytosis after hemorrhoidectomy and treatment with methotrexate--listeriosis with cerebral abscess].

  Deutsche medizinische Wochenschrift (1946) 20090601

• Fibromatosis of the neck causing airway obstruction managed effectively with weekly low-dose methotrexate and vinblastine.

  Hong Kong medical journal = Xianggang yi xue za zhi 20090601

• Fatal pancytopenia in a hemodialysis patient after treatment with low-dose methotrexate.

  Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20090601

• First trimester bleeding.

  American family physician 20090601

• Acquired acute myelogenous leukemia after therapy for acute promyelocytic leukemia with t(15;17): a case report and review of the literature.

  Puerto Rico health sciences journal 20090601

• Potential for methotrexate exposure through contamination during parenteral use as an immunosuppressant.

  Internal medicine journal 20090601

• Serendipity-methotrexate and 6-mercaptopurine for continuation therapy for patients with acute lymphoblastic leukemia: the leukemic stem cell and beyond?

  Journal of pediatric hematology/oncology 20090601

• Oral methotrexate/6-mercaptopurine may be superior to a multidrug LSA2L2 Maintenance therapy for higher risk childhood acute lymphoblastic leukemia: results from the NOPHO ALL-92 study.

  Journal of pediatric hematology/oncology 20090601

• Genetic polymorphisms in folate pathway enzymes as a possible marker for predicting the outcome of methotrexate therapy in Japanese patients with rheumatoid arthritis.

  Journal of clinical pharmacy and therapeutics 20090601

• Phase III trial evaluating the addition of paclitaxel to doxorubicin followed by cyclophosphamide, methotrexate, and fluorouracil, as adjuvant or primary systemic therapy: European Cooperative Trial in Operable Breast Cancer.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090520

• Adults with acute lymphoblastic leukemia and translocation (1;19) abnormality have a favorable outcome with hyperfractionated cyclophosphamide, vincristine, doxorubicin, and dexamethasone alternating with methotrexate and high-dose cytarabine chemotherapy.

  Cancer 20090515

• Quantitative phosphorus metabolomics using nanoflow liquid chromatography-tandem mass spectrometry and culture-derived comprehensive global internal standards.

  Analytical chemistry 20090515

• Development and validation of a composite disease activity score for juvenile idiopathic arthritis.

  Arthritis and rheumatism 20090515

• Low-dose methotrexate enhances aminolevulinate-based photodynamic therapy in skin carcinoma cells in vitro and in vivo.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20090515

• Synthesis and biological activity of a novel series of 6-substituted thieno[2,3-d]pyrimidine antifolate inhibitors of purine biosynthesis with selectivity for high affinity folate receptors over the reduced folate carrier and proton-coupled folate transporter for cellular entry.

  Journal of medicinal chemistry 20090514

• Adjuvant chemotherapy in older women with early-stage breast cancer.

  The New England journal of medicine 20090514

• Acquired variation outweighs inherited variation in whole genome analysis of methotrexate polyglutamate accumulation in leukemia.

  Blood 20090507

• Limited value of cyclosporine A for the treatment of patients with uveitis associated with juvenile idiopathic arthritis.

  Eye (London, England) 20090501

• Intractable epilepsy in patients treated for childhood acute lymphocytic leukemia.

  Seizure 20090501

• C677T and A1298C MTHFR polymorphisms, a challenge for antifolate and fluoropyrimidine-based therapy personalisation.

  European journal of cancer (Oxford, England : 1990) 20090501

• Methotrexate in pediatric osteosarcoma: response and toxicity in relation to genetic polymorphisms and dihydrofolate reductase and reduced folate carrier 1 expression.

  The Journal of pediatrics 20090501

• Liver fibrosis in patients with psoriasis and psoriatic arthritis on long-term, high cumulative dose methotrexate therapy.

  Rheumatology (Oxford, England) 20090501

• Leptin accelerates enterocyte turnover during methotrexate-induced intestinal mucositis in a rat.

  Cancer biology & therapy 20090501

• Methotrexate and aminopterin exhibit similar in vitro and in vivo preclinical activity against acute lymphoblastic leukaemia and lymphoma.

  British journal of haematology 20090501

• The BeSt story: on strategy trials in rheumatoid arthritis.

  Current opinion in rheumatology 20090501

• Spondyloarthropathy and chronic B hepatitis. Effect of anti-TNF therapy.

  Joint, bone, spine : revue du rhumatisme 20090501

• Nuclear translocation of dihydrofolate reductase is not a pre-requisite for DNA damage induced apoptosis.

  Apoptosis : an international journal on programmed cell death 20090501

• Mycophenolate mofetil combined with tacrolimus and minidose methotrexate after unrelated donor bone marrow transplantation with reduced-intensity conditioning.

  International journal of hematology 20090501

• Long-term efficacy and toxicity of ciclosporin A in combination with methotrexate in poor prognosis rheumatoid arthritis.

  Annals of the rheumatic diseases 20090501

• X-ray structure of the ternary MTX.NADPH complex of the anthrax dihydrofolate reductase: a pharmacophore for dual-site inhibitor design.

  Journal of structural biology 20090501

• Functionally overlapping roles of Abcg2 (Bcrp1) and Abcc2 (Mrp2) in the elimination of methotrexate and its main toxic metabolite 7-hydroxymethotrexate in vivo.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20090501

• The good initial response to therapy with a combination of traditional disease-modifying antirheumatic drugs is sustained over time: the eleven-year results of the Finnish rheumatoid arthritis combination therapy trial.

  Arthritis and rheumatism 20090501

• Efficacy, pharmacodynamics, and safety of VX-702, a novel p38 MAPK inhibitor, in rheumatoid arthritis: results of two randomized, double-blind, placebo-controlled clinical studies.

  Arthritis and rheumatism 20090501

• Methotrexate treatment in pediatric Crohn disease patients intolerant or resistant to purine analogues.

  Journal of pediatric gastroenterology and nutrition 20090501

• Delayed recognition of intrathecal methotrexate overdose.

  Journal of pediatric hematology/oncology 20090501

• Folic acid-induced anaphylaxis showing cross-reactivity with methotrexate: a case report and review of the literature.

  International journal of dermatology 20090501

• Isolated central nervous system posttransplant lymphoproliferative disorder treated with high-dose intravenous methotrexate.

  American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20090501

• Role of the MTHFR polymorphisms in cancer risk modification and treatment.

  Future oncology (London, England) 20090501

• Surgical resection in the management of pulmonary metastatic disease of gestational trophoblastic neoplasia.

  International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20090501

• [Efficacy of modified B-NHL-BFM-90 protocol on anaplastic T-cell lymphoma in children and adolescents].

  Ai zheng = Aizheng = Chinese journal of cancer 20090501

• Aberrant splicing of folylpolyglutamate synthetase as a novel mechanism of antifolate resistance in leukemia.

  Blood 20090430

• A 245kb mini-chromosome impacts on Leishmania braziliensis infection and survival.

  Biochemical and biophysical research communications 20090424

• CNS events in elderly patients with aggressive lymphoma treated with modern chemotherapy (CHOP-14) with or without rituximab: an analysis of patients treated in the RICOVER-60 trial of the German High-Grade Non-Hodgkin Lymphoma Study Group (DSHNHL).

  Blood 20090423

• Combination chemotherapy for high-risk gestational trophoblastic tumour.

  The Cochrane database of systematic reviews 20090415

• Gene expression profiling of leukemia T-cells resistant to methotrexate and 7-hydroxymethotrexate reveals alterations that preserve intracellular levels of folate and nucleotide biosynthesis.

  Biochemical pharmacology 20090415

• [Therapeutic strategies in idiopatic inflammatory myopathies].

  Revue medicale suisse 20090415

• Polymer-modified gadolinium metal-organic framework nanoparticles used as multifunctional nanomedicines for the targeted imaging and treatment of cancer.

  Biomacromolecules 20090413

• Phase III study of gefitinib compared with intravenous methotrexate for recurrent squamous cell carcinoma of the head and neck [corrected].

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090410

• Dancing of the second aromatic residue around the 6,8-diazabicyclo[3.2.2]nonane framework: influence on sigma receptor affinity and cytotoxicity.

  Journal of medicinal chemistry 20090409

• Methotrexate-related leukoencephalopathy without radiation therapy: distribution of brain lesions and pathological heterogeneity on two autopsy cases.

  Neuropathology : official journal of the Japanese Society of Neuropathology 20090401

• Protective effect of aged garlic extract (AGE) on the apoptosis of intestinal epithelial cells caused by methotrexate.

  Cancer chemotherapy and pharmacology 20090401

• Term delivery following successful treatment of choriocarcinoma with brain metastases, a case report and review of literature.

  Archives of gynecology and obstetrics 20090401

• High-dose methotrexate for elderly patients with primary CNS lymphoma.

  Neuro-oncology 20090401

• Favorable outcome with chemo-immunotherapy in Burkitt lymphoma and leukemia.

  Leukemia research 20090401

• Gestational trophoblastic tumor with liver metastasis after misoprostol abortion.

  Archives of gynecology and obstetrics 20090401

• Development of pemphigus vulgaris in a patient with psoriasis treated with etanercept.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20090401

• Prophylaxis regimens for GVHD: systematic review and meta-analysis.

  Bone marrow transplantation 20090401

• No salvage using high-dose chemotherapy plus/minus reirradiation for relapsing previously irradiated medulloblastoma.

  International journal of radiation oncology, biology, physics 20090401

• Increased risk of tuberculosis in patients treated with antitumor necrosis factor alpha.

  Clinical rheumatology 20090401

• Chemotherapy induced esophageal stricture.

  Pediatric blood & cancer 20090401

• Evaluation of different methods used to assess disease activity in rheumatoid arthritis: analyses of abatacept clinical trial data.

  Annals of the rheumatic diseases 20090401

• Mechanisms of gene amplification and evidence of coamplification in drug-resistant human osteosarcoma cell lines.

  Genes, chromosomes & cancer 20090401

• Intestinal breast cancer resistance protein (BCRP)/Bcrp1 and multidrug resistance protein 3 (MRP3)/Mrp3 are involved in the pharmacokinetics of resveratrol.

  Molecular pharmacology 20090401

• High-performance capillary electrophoretic method for the quantification of global DNA methylation: application to methotrexate-resistant cells.

  Analytical biochemistry 20090401

• Changes in acetylcholinesterase (AchE) activity in lymphocytes and whole blood in acute lymphoblastic leukemia patients.

  Clinica chimica acta; international journal of clinical chemistry 20090401

• Successful treatment of pyoderma gangrenosum associated with juvenile idiopathic arthritis with a combination of topical tacrolimus and oral prednisolone.

  Clinical rheumatology 20090401

• Effect of growth hormone on testicular dysfunction induced by methotrexate in rats.

  Andrologia 20090401

• First-line therapy for chronic graft-versus-host disease that includes low-dose methotrexate is associated with a high response rate.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20090401

• Mesial temporal sclerosis associated with methotrexate-induced leukoencephalopathy.

  Pediatric neurology 20090401

• An improved high-performance liquid chromatography method for quantification of methotrexate polyglutamates in red blood cells of children with juvenile idiopathic arthritis.

  Biopharmaceutics & drug disposition 20090401

• Intraocular methotrexate in the treatment of uveitis and uveitic cystoid macular edema.

  Ophthalmology 20090401

• Management of patients with primary central nervous system lymphoma treated with high-dose methotrexate.

  Clinical journal of oncology nursing 20090401

• [Expression and function of Ahi-1 gene in Jurkat cells].

  Zhongguo shi yan xue ye xue za zhi 20090401

• Reactive arthritis associated with hidradenitis suppurativa.

  Journal of the National Medical Association 20090401

• Noninvasive bioluminescent and microPET imaging for the regulation of NF-kappaB in human hepatoma-bearing mice.

  Anticancer research 20090401

• Sex- and age-related chemotherapy toxicity in patients with non-metastatic osteosarcoma.

  Journal of chemotherapy (Florence, Italy) 20090401

• Determination of bezafibrate, methotrexate, cyclophosphamide, orlistat and enalapril in waste and surface waters using on-line solid-phase extraction liquid chromatography coupled to polarity-switching electrospray tandem mass spectrometry.

  Journal of environmental monitoring : JEM 20090401

• Targeted delivery of methotrexate to skeletal muscular tissue by thermosensitive magnetoliposomes.

  International journal of pharmaceutics 20090331

• Plant Vacuolar ATP-binding Cassette Transporters That Translocate Folates and Antifolates in Vitro and Contribute to Antifolate Tolerance in Vivo.

  The Journal of biological chemistry 20090327

• External validation of serum hCG cutoff levels for prediction of resistance to single-agent chemotherapy in patients with persistent trophoblastic disease.

  British journal of cancer 20090324

• Oral uracil and tegafur compared with classic cyclophosphamide, methotrexate, fluorouracil as postoperative chemotherapy in patients with node-negative, high-risk breast cancer: National Surgical Adjuvant Study for Breast Cancer 01 Trial.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090320

• The enzymatic activity of 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase is enhanced by NPM-ALK: new insights in ALK-mediated pathogenesis and the treatment of ALCL.

  Blood 20090319

• Glycyrrhizin and licorice significantly affect the pharmacokinetics of methotrexate in rats.

  Journal of agricultural and food chemistry 20090311

• Dynamic dysfunction in dihydrofolate reductase results from antifolate drug binding: modulation of dynamics within a structural state.

  Structure (London, England : 1993) 20090311

• Bone mineral density in rheumatoid arthritis patients 1 year after adalimumab therapy: arrest of bone loss.

  Annals of the rheumatic diseases 20090301

• Thermo-triggered and biotinylated biotin-P(NIPAAm-co-HMAAm)-b-PMMA micelles for controlled drug release.

  Journal of biomedical materials research. Part A 20090301

• Renal dysfunction during and after high-dose methotrexate.

  Cancer chemotherapy and pharmacology 20090301

• Complete hydatidiform mole in a perimenopausal woman with a subsequent severe thyriotoxicosis.

  Archives of gynecology and obstetrics 20090301

• Evaluation of surface contamination in a hospital hematology--oncology pharmacy.

  Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners 20090301

• Evaluation of osmolality and pH of various concentrations of methotrexate, cytarabine, and thiotepa prepared in normal saline, sterile water for injection, and lactated Ringer's solution for intrathecal administration.

  Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners 20090301

• Effect of folic or folinic acid supplementation on methotrexate-associated safety and efficacy in inflammatory disease: a systematic review.

  The British journal of dermatology 20090301

• Rapid complete cytogenetic remission after upfront dasatinib monotherapy in a patient with a NUP214-ABL1-positive T-cell acute lymphoblastic leukemia.

  Leukemia 20090301

• Intrathecal chemotherapy for hematologic malignancies: drugs and toxicities.

  Annals of hematology 20090301

• MTHFR 677 C>T genotype and adverse outcomes in treatment of childhood ALL: is the jury in?

  Pediatric blood & cancer 20090301

• Increasing use of more potent treatments for psoriasis.

  Journal of the American Academy of Dermatology 20090301

• What the first 10,000 patients with chronic urticaria have taught me: a personal journey.

  The Journal of allergy and clinical immunology 20090301

• Maternal and perinatal outcomes of first pregnancy after chemotherapy for gestational trophoblastic neoplasia in Brazilian women.

  Gynecologic oncology 20090301

• Methotrexate-incorporated polymeric nanoparticles of methoxy poly(ethylene glycol)-grafted chitosan.

  Colloids and surfaces. B, Biointerfaces 20090301

• A case of a methotrexate-resistant ectopic pregnancy in which dactinomycin was effective as a second-line chemotherapy.

  Fertility and sterility 20090301

• [Leflunomide in combination with TNF-blockers for Methotrexate intolerance].

  Zeitschrift fur Rheumatologie 20090301

• Proliferation predicts failure-free survival in mantle cell lymphoma patients treated with rituximab plus hyperfractionated cyclophosphamide, vincristine, doxorubicin, and dexamethasone alternating with rituximab plus high-dose methotrexate and cytarabine.

  Cancer 20090301

• Spinal cord sarcoidosis: report of seven cases.

  European journal of neurology 20090301

• Low-dose capecitabine plus docetaxel as first-line therapy for metastatic breast cancer: phase II results.

  Anti-cancer drugs 20090301

• [Autoimmune vasculitides. Standards and guidelines of EULAR and EUVAS].

  Der Internist 20090301

• Metaanalysis of methylenetetrahydrofolate reductase (MTHFR) polymorphisms affecting methotrexate toxicity.

  The Journal of rheumatology 20090301

• Endemic Burkitt lymphoma: a 28-day treatment schedule with cyclophosphamide and intrathecal methotrexate.

  Annals of tropical paediatrics 20090301

• Patients with moderate rheumatoid arthritis (RA) achieve better disease activity states with etanercept treatment than patients with severe RA.

  The Journal of rheumatology 20090301

• Involvement of breast cancer resistance protein expression on rheumatoid arthritis synovial tissue macrophages in resistance to methotrexate and leflunomide.

  Arthritis and rheumatism 20090301

• [Effect of disease modifying anti-rheumatic drugs on radiographic progression in rheumatoid arthritis].

  Clinical calcium 20090301

• Effect of methotrexate treatment on expression levels of organic anion transporter polypeptide 2, P-glycoprotein and bile salt export pump in rats.

  Biological & pharmaceutical bulletin 20090301

• Yolk sac on transvaginal ultrasound as a prognostic indicator in the treatment of ectopic pregnancy with single-dose methotrexate.

  American journal of obstetrics and gynecology 20090301

• Severe hepatotoxicity in a patient on bosentan upon addition of methotrexate: reversible with resumption of methotrexate without bosentan.

  Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20090301

• [Immunosuppressants].

  Nihon rinsho. Japanese journal of clinical medicine 20090301

• [A case of bone marrow carcinosis from gastric cancer that presented hypocalcemia caused by zoledronic acid during the treatment of methotrexate/5-fluorouracil sequential therapy].

  Gan to kagaku ryoho. Cancer & chemotherapy 20090301

• Feasibility and efficacy of intraarticular steroids (IAS) in juvenile idiopathic arthritis (JIA).

  Indian pediatrics 20090301

• Medical therapy of IBD in 2009.

  Medicine and health, Rhode Island 20090301

• [Prolonged complete clinical remission in patients with severe pemphigus vulgaris after cycles of intravenous cyclophosphamide].

  Actas dermo-sifiliograficas 20090301

• [Epidemiology of pemphigus in the Hospital Universitario Virgen Macarena, Seville, Spain, 2005-2006].

  Actas dermo-sifiliograficas 20090301

• [Financial cost of early rheumatoid arthritis in the first year of medical attention: three clinical scenarios in a third-tier university hospital in Colombia].

  Biomedica : revista del Instituto Nacional de Salud 20090301

• Inflammation in methotrexate-induced pulmonary toxicity occurs via the p38 MAPK pathway.

  Toxicology 20090227

• Impact of the methotrexate administration dose on the need for intrathecal treatment in children and adolescents with anaplastic large-cell lymphoma: results of a randomized trial of the EICNHL Group.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090220

• Methotrexate-induced cytotoxicity and genotoxicity in germ cells of mice: intervention of folic and folinic acid.

  Mutation research 20090219

• Lack of pathologic down-staging with neoadjuvant chemotherapy for muscle-invasive urothelial carcinoma of the bladder: a contemporary series.

  Cancer 20090215

• Long-term benefit of high-dose epirubicin in adjuvant chemotherapy for node-positive breast cancer: 15-year efficacy results of the Belgian multicentre study.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090210

• Results of the Avonex Combination Trial (ACT) in relapsing-remitting MS.

  Neurology 20090210

• Fifteen-year median follow-up results after neoadjuvant doxorubicin, followed by mastectomy, followed by adjuvant cyclophosphamide, methotrexate, and fluorouracil (CMF) followed by radiation for stage III breast cancer: a phase II trial (CALGB 8944).

  Breast cancer research and treatment 20090201

• Novel 8-deaza-5,6,7,8-tetrahydroaminopterin derivatives as dihydrofolate inhibitor: design, synthesis and antifolate activity.

  European journal of medicinal chemistry 20090201

• Accelerated pulmonary nodulosis and sterile pleural effusion in a patient with psoriatic arthropathy during methotrexate therapy: a case report.

  Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20090201

• Systemic high-dose methotrexate plus ifosfamide is highly effective for central nervous system (CNS) involvement of lymphoma.

  Annals of hematology 20090201

• Sodium butyrate enhances the cytotoxic effect of antineoplastic drugs in human lymphoblastic T-cells.

  Leukemia research 20090201

• Association of genetic variants of methionine metabolism with methotrexate-induced CNS white matter changes in patients with primary CNS lymphoma.

  Neuro-oncology 20090201

• Methotrexate for the treatment of juvenile idiopathic arthritis: process to approval for JIA indication in Japan.

  Modern rheumatology 20090201

• Control of aggressive fibromatosis by treatment with imatinib mesylate: a step forward?

  Journal of cancer research and clinical oncology 20090201

• Histone acetylation resulting in resistance to methotrexate in choroid plexus cells.

  Journal of neuro-oncology 20090201

• High-dose methotrexate combined with procarbazine and CCNU for primary CNS lymphoma in the elderly: results of a prospective pilot and phase II study.

  Annals of oncology : official journal of the European Society for Medical Oncology 20090201

• The effect of molecular weight, drug load, and charge of gelatin-MTX conjugates on growth inhibition of HL-60 leukemia cells.

  Pharmaceutical research 20090201

• Study of active controlled tocilizumab monotherapy for rheumatoid arthritis patients with an inadequate response to methotrexate (SATORI): significant reduction in disease activity and serum vascular endothelial growth factor by IL-6 receptor inhibition therapy.

  Modern rheumatology 20090201

• Interaction of anticancer drug methotrexate with nucleic acids analyzed by multi-spectroscopic method.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20090201

• Outcomes of methotrexate therapy for psoriasis and relationship to genetic polymorphisms.

  The British journal of dermatology 20090201

• Adjuvant chemotherapy for locally advanced urothelial carcinoma: an overview of the USC experience.

  World journal of urology 20090201

• Fluorometry of singlet oxygen generated via a photosensitized reaction using folic acid and methotrexate.

  Analytical and bioanalytical chemistry 20090201

• [Pneumocystis pneumonia among patients with systemic diseases].

  Presse medicale (Paris, France : 1983) 20090201

• Hyperfractionated accelerated radiotherapy in the Milan strategy for metastatic medulloblastoma.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090201

• Population pharmacokinetics of high-dose methotrexate after intravenous administration in pediatric patients with osteosarcoma.

  Therapeutic drug monitoring 20090201

• Liposomes containing alkylated methotrexate analogues for phospholipase A(2) mediated tumor targeted drug delivery.

  Chemistry and physics of lipids 20090201

• Randomised controlled trial of methotrexate for chronic inflammatory demyelinating polyradiculoneuropathy (RMC trial): a pilot, multicentre study.

  The Lancet. Neurology 20090201

• Balloon tamponade of hemorrhage after uterine curettage for gestational trophoblastic disease.

  Obstetrics and gynecology 20090201

• Management of imatinib-related exacerbation of psoriasis in a patient with a gastrointestinal stromal tumour.

  The Australasian journal of dermatology 20090201

• Evaluation of the efficacy and safety of pamapimod, a p38 MAP kinase inhibitor, in a double-blind, methotrexate-controlled study of patients with active rheumatoid arthritis.

  Arthritis and rheumatism 20090201

• Disease-modifying antirheumatic drugs.

  The Journal of hand surgery 20090201

• [Wegener's granulomatosis and microscopic polyangiitis].

  Zeitschrift fur Rheumatologie 20090201

• Dihydrofolate reductase amplification and sensitization to methotrexate of methotrexate-resistant colon cancer cells.

  Molecular cancer therapeutics 20090201

• High-dose methotrexate in pediatric oncology-back to bench from bedside for a while?

  Journal of pediatric hematology/oncology 20090201

• Little dose, huge toxicity: profound hematological toxicity of intrathecal methotrexate.

  Leukemia & lymphoma 20090201

• Sterile corneal melt after descemet stripping endothelial keratoplasty in patients with previously undiagnosed Sjogren syndrome.

  Archives of ophthalmology (Chicago, Ill. : 1960) 20090201

• Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia.

  JAMA 20090128

• [Treatment of Crohn's disease].

  Praxis 20090121

• Methotrexate for high-grade osteosarcoma in children and young adults.

  The Cochrane database of systematic reviews 20090121

• First line chemotherapy in low risk gestational trophoblastic neoplasia.

  The Cochrane database of systematic reviews 20090121

• Patient-reported outcomes in a randomized trial comparing four different treatment strategies in recent-onset rheumatoid arthritis.

  Arthritis and rheumatism 20090115

• Synthesis of 6-O-methotrexylhyaluronan as a drug delivery system.

  Carbohydrate research 20090105

• The effectiveness of leflunomide as a co-therapy of tumour necrosis factor inhibitors in rheumatoid arthritis: a population-based study.

  Annals of the rheumatic diseases 20090101

• Comparison among different classification systems regarding the pathological response of preoperative chemotherapy in relation to the long-term outcome.

  Breast cancer research and treatment 20090101

• Can clinical factors at presentation be used to predict outcome of treatment with methotrexate in patients with early inflammatory polyarthritis?

  Annals of the rheumatic diseases 20090101

• Is the pathobiology of chemotherapy-induced alimentary tract mucositis influenced by the type of mucotoxic drug administered?

  Cancer chemotherapy and pharmacology 20090101

• Cisplatin and gemcitabine in the management of metastatic penile cancer.

  Urologic oncology 20090101

• Analysis of differential therapeutic strategies for primary breast lymphoma: two case reports.

  Medical oncology (Northwood, London, England) 20090101

• Placental site trophoblastic tumor with multiple metastases and complete response to salvage BEP regimen: a case report and review of the literature.

  Medical oncology (Northwood, London, England) 20090101

• Rituximab-induced acute thrombocytopenia: a case report and review of the literature.

  Medical oncology (Northwood, London, England) 20090101

• Effective second-line chemotherapy for extranodal NK/T-cell lymphoma consisting of etoposide, ifosfamide, methotrexate, and prednisolone.

  Annals of oncology : official journal of the European Society for Medical Oncology 20090101

• Potential role of macrophage migration inhibitory factor in adult-onset Still's disease.

  Scandinavian journal of rheumatology 20090101

• Current concepts for the management of head and neck cancer: chemotherapy.

  Oral oncology 20090101

• Combination of CsA, MTX and low-dose, short-course mycophenolate mofetil for GVHD prophylaxis.

  Bone marrow transplantation 20090101

• Effects of leflunomide and methotrexate in rheumatoid arthritis detected by digital X-ray radiogrammetry and computer-aided joint space analysis.

  Rheumatology international 20090101

• Enhanced gene amplification in human cells knocked down for DNA-PKcs.

  DNA repair 20090101

• Etanercept improved primary biliary cirrhosis associated with rheumatoid arthritis.

  Joint, bone, spine : revue du rhumatisme 20090101

• Damaging effects of chronic low-dose methotrexate usage on primary bone formation in young rats and potential protective effects of folinic acid supplementary treatment.

  Bone 20090101

• Methotrexate induces intestinal mucositis and alters gut protein metabolism independently of reduced food intake.

  American journal of physiology. Endocrinology and metabolism 20090101

• Ankylosing spondylitis and IgA deficiency.

  Joint, bone, spine : revue du rhumatisme 20090101

• Differential influences of bucillamine and methotrexate on the generation of fibroblast-like cells from bone marrow CD34+ cells of rheumatoid arthritis patients.

  International immunopharmacology 20090101

• Methotrexate-associated alterations of the folate and methyl-transfer pathway in the CSF of ALL patients with and without symptoms of neurotoxicity.

  Pediatric blood & cancer 20090101

• 2,6,9-Trisubstituted purine derivatives as protein A mimetics for the treatment of autoimmune diseases.

  Bioorganic & medicinal chemistry letters 20090101

• Fetal methotrexate/aminopterin syndrome in an adult: a likely case with ectodermal abnormalities.

  Clinical dysmorphology 20090101

• Special focus on cardiac toxicity of different sequences of adjuvant doxorubicin/docetaxel/CMF regimens combined with radiotherapy in breast cancer patients.

  Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20090101

• Evaluation of the efficacy of the combination of oral bexarotene and methotrexate for the treatment of early stage treatment-refractory cutaneous T-cell lymphoma.

  The Journal of dermatological treatment 20090101

• Substrate selection by the proteasome during degradation of protein complexes.

  Nature chemical biology 20090101

• Phase II study of tacrolimus and methotrexate for prophylaxis of acute graft-versus-host disease after HLA-A, B, and DRB1 genotypically mismatched unrelated bone marrow transplantation among Japanese patients.

  International journal of hematology 20090101

• Folate homeostasis in cerebrospinal fluid during therapy for acute lymphoblastic leukemia.

  Pediatric neurology 20090101

• Co-administration of proton pump inhibitors delays elimination of plasma methotrexate in high-dose methotrexate therapy.

  British journal of clinical pharmacology 20090101

• C1 metabolism and chlorophyll synthesis: the Mg-protoporphyrin IX methyltransferase activity is dependent on the folate status.

  The New phytologist 20090101

• Poor treatment compliance in children with down syndrome and acute lymphoblastic leukemia.

  Journal of pediatric hematology/oncology 20090101

• Effects of methotrexate on the developments of heart and vessel in zebrafish.

  Acta biochimica et biophysica Sinica 20090101

• Study of kidney function impairment after reduced-intensity conditioning allogeneic hematopoietic stem cell transplantation. A single-center experience.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20090101

• Testicular function in poor-risk nonseminomatous germ cell tumors treated with methotrexate, paclitaxel, ifosfamide, and cisplatin combination chemotherapy.

  Journal of andrology 20090101

• Effect of oral glutamine on enterocyte turnover during methotrexate-induced mucositis in rats.

  Digestion 20090101

• Neutrophil infiltration and oxidative stress may play a critical role in methotrexate-induced renal damage.

  Chemotherapy 20090101

• [Evaluation of 5-fluorouracil-related genes in breast cancer to predict the effect of adjuvant therapy with CMF].

  Gan to kagaku ryoho. Cancer & chemotherapy 20090101

• Adult-onset Stills disease with a cellulitis-like eruption.

  European journal of dermatology : EJD 20090101

• Combination treatment with leflunomide and methotrexate for patients with active rheumatoid arthritis.

  Scandinavian journal of rheumatology 20090101

• Antirheumatic drug response signatures in human chondrocytes: potential molecular targets to stimulate cartilage regeneration.

  Arthritis research & therapy 20090101

• Evaluation of chemotherapy response in osteosarcoma with FDG-PET.

  Annals of nuclear medicine 20090101

• Point mutation of tyrosine 759 of the IL-6 family cytokine receptor, gp130, augments collagen-induced arthritis in DBA/1J mice.

  BMC musculoskeletal disorders 20090101

• Contemporary use of disease-modifying drugs in the management of patients with early rheumatoid arthritis in Norway.

  Scandinavian journal of rheumatology 20090101

• Ovarian suppression/ablation in premenopausal ER-positive breast cancer patients. Issues and recommendations.

  Oncology (Williston Park, N.Y.) 20090101

• [Isoniazid prophylaxis for pulmonary tuberculosis in Chinese patients with rheumatoid arthritis receiving long-term methotrexate therapy].

  Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20090101

• Tumor d'emblee responding to methotrexate and prednisolone.

  Indian journal of dermatology, venereology and leprology 20090101

• Intensive chemotherapy for a patient with primary cutaneous diffuse large B-cell lymphoma with Burkitt-like morphology.

  Internal medicine (Tokyo, Japan) 20090101

• Bilateral episcleritis as a manifestation of cutaneous leukocytoclastic vasculitis.

  Ocular immunology and inflammation 20090101

• TLE3 as a candidate biomarker of response to taxane therapy.

  Breast cancer research : BCR 20090101

• Associations between methotrexate treatment and methylenetetrahydrofolate reductase gene polymorphisms with incident fractures in Japanese female rheumatoid arthritis patients.

  Journal of bone and mineral metabolism 20090101

• Prognostic significance of location of the primary tumor in operable breast cancers.

  Indian journal of cancer 20090101

• Concurrent chemoradiotherapy in adjuvant treatment of breast cancer.

  Radiation oncology (London, England) 20090101

• [Methotrexate in the treatment of peripheral arthritis in ulcerative colitis].

  Reumatismo 20090101

• Limb-sparing in patients with non-metastatic high-grade osteosarcoma.

  Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20090101

• [Portuguese recommendations for the use of methotrexate in the treatment of rheumatoid arthritis].

  Acta reumatologica portuguesa 20090101

• [Treatment of rapidly progressive glomerulonephritis].

  Nihon Jinzo Gakkai shi 20090101

• Effects of low-dose mizoribine pulse therapy in combination with methotrexate in rheumatoid arthritis patients with an insufficient response to methotrexate.

  Modern rheumatology 20090101

• [The network of methotrexate toxicity].

  Acta reumatologica portuguesa 20090101

• A new agent for tumour necrosis factor-alpha inhibition: In vitro effects of dipyridamole in Crohn's disease.

  Scandinavian journal of clinical and laboratory investigation 20090101

• Refractory abdominal pain--atypical presentation of Takayasu's arteritis.

  Pain medicine (Malden, Mass.) 20090101

• Lack of in vitro interactions using human liver microsomes between rabeprazole and anticancer drugs.

  European journal of drug metabolism and pharmacokinetics 20090101

• Effect of methotrexate and anti-TNF on Epstein-Barr virus T-cell response and viral load in patients with rheumatoid arthritis or spondylarthropathies.

  Arthritis research & therapy 20090101

• Disability measured by the modified health assessment questionnaire in early rheumatoid arthritis: prognostic factors after two years of follow-up.

  Clinical and experimental rheumatology 20090101

• Effect of methotrexate on the survival of human lymphocyte cultures carrying MTHFR 677 (C>T) and MTHFR 1298 (A>C) mutations.

  Drug and chemical toxicology 20090101

• Leflunomide-induced polymyositis in a patient with rheumatoid arthritis.

  Modern rheumatology 20090101

• Clinical impact of B-cell depletion with the anti-CD20 antibody rituximab in chronic fatigue syndrome: a preliminary case series.

  BMC neurology 20090101

• Prediction of DAS28-ESR remission at 6 months by baseline variables in patients with rheumatoid arthritis treated with etanercept in Japanese population.

  Modern rheumatology 20090101

• Rituximab therapy in patients with rheumatoid arthritis refractory or with contraindication to anti-tumour necrosis factor drugs: real-life experience in Finnish patients.

  Scandinavian journal of rheumatology 20090101

• Successful treatment of systemic-sclerosis-related digital ulcers with a selective endothelin type A receptor antagonist (sitaxentan).

  Dermatology (Basel, Switzerland) 20090101

• Chemomodulation of human dendritic cell function by antineoplastic agents in low noncytotoxic concentrations.

  Journal of translational medicine 20090101

• Long-term efficacy of leflunomide on disease activity and inhibition of joint damage: retrospective comparison with methotrexate for Japanese rheumatoid arthritis patients.

  Modern rheumatology 20090101

• Methylenetetrahydrofolate reductase polymorphisms and methotrexate: no association with response to therapy nor with drug-related adverse events in an Italian population of rheumatic patients.

  Clinical and experimental rheumatology 20090101

• Methotrexate therapy associates with reduced prevalence of the metabolic syndrome in rheumatoid arthritis patients over the age of 60- more than just an anti-inflammatory effect? A cross sectional study.

  Arthritis research & therapy 20090101

• [Methylenetetrahydrofolate reductase polymorphisms in methotrexate treatment of rheumatoid arthritis patients. Review of the literature and personal experience].

  Reumatismo 20090101

• Scleroderma linearis: hemiatrophia faciei progressiva (Parry-Romberg syndrom) without any changes in CNS and linear scleroderma 'en coup de sabre' with CNS tumor.

  BMC neurology 20090101

• Early diagnosis of pediatric Takayasu arteritis (TA) not fullfiling the ACR criteria.

  Clinical and experimental rheumatology 20090101

• [Combined basic therapy of rheumatoid arthritis with methotrexate and plaquenil].

  Terapevticheskii arkhiv 20090101

• [Rituximab treatment of rheumatoid arthritis: new evidence].

  Terapevticheskii arkhiv 20090101

• Infliximab treatment reduces the serum levels of interleukin-23 in patients with rheumatoid arthritis.

  Modern rheumatology 20090101

• [Acute toxicity of high doses of methotrexate in treatment of ALL in children: a case study].

  Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20090101

• A lentivirus-mediated genetic screen identifies dihydrofolate reductase (DHFR) as a modulator of beta-catenin/GSK3 signaling.

  PloS one 20090101

• Metastatic breast cancer survival according to HER2 and Topo2a gene status.

  Disease markers 20090101

• Networking of differentially expressed genes in human cancer cells resistant to methotrexate.

  Genome medicine 20090101

• ZNF93 increases resistance to ET-743 (Trabectedin; Yondelis) and PM00104 (Zalypsis) in human cancer cell lines.

  PloS one 20090101

• Tumor tissue levels of Tissue Inhibitor of Metalloproteinases-1 (TIMP-1) and outcome following adjuvant chemotherapy in premenopausal lymph node-positive breast cancer patients: A retrospective study.

  BMC cancer 20090101

• Suppressive effect of secretory phospholipase A2 inhibitory peptide on interleukin-1beta-induced matrix metalloproteinase production in rheumatoid synovial fibroblasts, and its antiarthritic activity in hTNFtg mice.

  Arthritis research & therapy 20090101

• Methotrexate information booklet study 2008.

  Clinical and experimental rheumatology 20090101

• Preclinical characterization of DEKAVIL (F8-IL10), a novel clinical-stage immunocytokine which inhibits the progression of collagen-induced arthritis.

  Arthritis research & therapy 20090101

• [Correct use of methotrexate].

  Nederlands tijdschrift voor geneeskunde 20090101

• Immunomodulation with methotrexate: underused and undervalued?

  Digestive diseases (Basel, Switzerland) 20090101

• Mild to moderate Crohn's disease: still room for step-up therapies?

  Digestive diseases (Basel, Switzerland) 20090101

• Drug monitoring in inflammatory bowel disease: helpful or dispensable?

  Digestive diseases (Basel, Switzerland) 20090101

• Prediction of DAS28-CRP remission in patients with rheumatoid arthritis treated with tacrolimus at 6 months by baseline variables.

  Modern rheumatology 20090101

• Use of methotrexate therapy is not associated with decreased prevalence of metabolic syndrome.

  Arthritis research & therapy 20090101

• Graves' disease associated with primary systemic sclerosis.

  Orbit (Amsterdam, Netherlands) 20090101

• Combined oral corticosteroid-methotrexate therapy in Eales' disease.

  Annals of ophthalmology (Skokie, Ill.) 20090101

• Effect of charcoal hemoperfusion for removal of plasma methotrexate in a patient with acute renal failure.

  Pediatric hematology and oncology 20090101

• New guidelines for managing psoriasis with systemic medications.

  Dermatology nursing 20090101

• Effects of methotrexate on plasma cytokines and cardiac remodeling and function in postmyocarditis rats.

  Mediators of inflammation 20090101

• Infliximab treatment in a case of rheumatoid scleromalacia perforans.

  Reumatismo 20090101

• Information technology facilitates cost-effectiveness analysis in developing countries: an observational study of breast cancer chemotherapy in Taiwan.

  PharmacoEconomics 20090101

• Efficacy of sequential methotrexate and 5-fluorouracil (MTX/5FU) in improving oral intake in patients with advanced gastric cancer with severe peritoneal dissemination.

  Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 20090101

• Rapid and sustained improvements in health-related quality of life, fatigue, and other patient-reported outcomes in rheumatoid arthritis patients treated with certolizumab pegol plus methotrexate over 1 year: results from the RAPID 1 randomized controlled trial.

  Arthritis research & therapy 20090101

• A multicenter, double-blind, randomized, controlled phase III clinical trial of chicken type II collagen in rheumatoid arthritis.

  Arthritis research & therapy 20090101

• A combination of methotrexate and zoledronic acid prevents bone erosions and systemic bone mass loss in collagen induced arthritis.

  Arthritis research & therapy 20090101

• Dendrimer-based nanoparticles for cancer therapy.

  Hematology. American Society of Hematology. Education Program 20090101

• Chemosensitizing effect of nordihydroguaiaretic acid and its tetra-acetylated derivative on parental and multiresistant TA3 mouse mammary adenocarcinoma cells.

  In vivo (Athens, Greece) 20090101

• MiR-24 tumor suppressor activity is regulated independent of p53 and through a target site polymorphism.

  PloS one 20090101

• Successful endonasal dacryocystorhinostomy in a patient with Wegener's granulomatosis.

  Clinical ophthalmology (Auckland, N.Z.) 20090101

• The economic burden of biological therapy in rheumatoid arthritis in clinical practice: cost-effectiveness analysis of sub-cutaneous anti-TNFalpha treatment in Italian patients.

  International journal of immunopathology and pharmacology 20090101

• [Influence of immunodepressors on population level and adhesive characteristics of opportunistic bacteria in large intestine of white mice].

  Zhurnal mikrobiologii, epidemiologii, i immunobiologii 20090101

• [Pancytopenia after methotrexate treatment].

  Wiadomosci lekarskie (Warsaw, Poland : 1960) 20090101

• Construction of expression system of rabbit aldehyde oxidase cDNA for the clarification of species differences.

  European journal of drug metabolism and pharmacokinetics 20090101

• [Role of adjuvant chemotherapy in the choice of chemotherapeutic treatment of metastatic breast cancer].

  La Clinica terapeutica 20090101

• Metronomic chemotherapy against cancer: from paradigm to clinical practice?

  Tumori 20090101

• Osteosarcoma: review of the past, impact on the future. The American experience.

  Cancer treatment and research 20090101

• Radiosynoviorthesis of the temporomandibular joint--initial clinical application.

  Nuklearmedizin. Nuclear medicine 20090101

• Azathioprine or methotrexate maintenance for ANCA-associated vasculitis.

  The New England journal of medicine 20081225

• Dendritic multishell architectures for drug and dye transport.

  Journal of controlled release : official journal of the Controlled Release Society 20081218

• Steroid-sparing effects of methotrexate in systemic lupus erythematosus: a double-blind, randomized, placebo-controlled trial.

  Arthritis and rheumatism 20081215

• miR-192 Regulates dihydrofolate reductase and cellular proliferation through the p53-microRNA circuit.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20081215

• Improved survival in lymphoma patients receiving sirolimus for graft-versus-host disease prophylaxis after allogeneic hematopoietic stem-cell transplantation with reduced-intensity conditioning.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20081210

• Characteristics and outcome of connective tissue diseases in patients with sickle-cell disease: report of 30 cases.

  Seminars in arthritis and rheumatism 20081201

• Autoerythrocyte sensitization syndrome (Gardner-Diamond syndrome) associated with cutaneous vasculitis.

  Joint, bone, spine : revue du rhumatisme 20081201

• Pharmacologic profiling of human and rat cytochrome P450 1A1 and 1A2 induction and competition.

  Archives of toxicology 20081201

• Structure-based approach to pharmacophore identification, in silico screening, and three-dimensional quantitative structure-activity relationship studies for inhibitors of Trypanosoma cruzi dihydrofolate reductase function.

  Proteins 20081201

• Long-term risk of malignancy among patients treated with immunosuppressive agents for ocular inflammation: a critical assessment of the evidence.

  American journal of ophthalmology 20081201

• Rheumatoid arthritis, alcohol, leflunomide and methotrexate. Can changes to the BSR guidelines for leflunomide and methotrexate on alcohol consumption be justified?

  Musculoskeletal care 20081201

• Minimal residual disease is an important predictive factor of outcome in children with relapsed 'high-risk' acute lymphoblastic leukemia.

  Leukemia 20081201

• Primary meningeal CNS lymphoma treated with intra-arterial chemotherapy and blood-brain barrier disruption.

  Journal of neuro-oncology 20081201

• Structural determinants of substrate specificity differences between human multidrug resistance protein (MRP) 1 (ABCC1) and MRP3 (ABCC3).

  Drug metabolism and disposition: the biological fate of chemicals 20081201

• Sirolimus is associated with veno-occlusive disease of the liver after myeloablative allogeneic stem cell transplantation.

  Blood 20081201

• Severe acute renal failure following high-dose methotrexate therapy in adults with haematological malignancies: a significant number result from unrecognized co-administration of several drugs.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20081201

• A novel assay to assess the effectiveness of antiangiogenic drugs in human breast cancer.

  Annals of surgical oncology 20081201

• Infliximab effects compared to conventional therapy in the management of retinal vasculitis in Behçet disease.

  American journal of ophthalmology 20081201

• A genome-wide and metabolic analysis determined the adaptive response of Arabidopsis cells to folate depletion induced by methotrexate.

  Plant physiology 20081201

• Juvenile localised scleroderma: a retrospective review of response to systemic treatment.

  Irish journal of medical science 20081201

• Surface-engineered dendrimers for dual drug delivery: a receptor up-regulation and enhanced cancer targeting strategy.

  Journal of drug targeting 20081201

• DMARDS and infections in rheumatoid arthritis.

  Autoimmunity reviews 20081201

• Elevated alanine aminotransferase levels associated with polymyositis: can this be due to muscle injury?

  Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20081201

• Atheroprotective effects of methotrexate on reverse cholesterol transport proteins and foam cell transformation in human THP-1 monocyte/macrophages.

  Arthritis and rheumatism 20081201

• Liposomal methotrexate hydrogel for treatment of localized psoriasis: preparation, characterization and laser targeting.

  Medical science monitor : international medical journal of experimental and clinical research 20081201

• The role of reactive oxygen species in immunopathogenesis of rheumatoid arthritis.

  Iranian journal of allergy, asthma, and immunology 20081201

• A comparison of vitamin A and leucovorin for the prevention of methotrexate-induced micronuclei production in rat bone marrow.

  Clinics (Sao Paulo, Brazil) 20081201

• First human treatment of resistant neoplastic meningitis by intrathecal administration of MTX plus (125)IUdR.

  International journal of radiation biology 20081201

• Sentinel lymph node biopsy after preoperative chemotherapy for breast cancer: findings from the Austrian Sentinel Node Study Group.

  Annals of surgical oncology 20081201

• Myeloablative cord blood transplantation for adults with hematological malignancies using tacrolimus and short-term methotrexate for graft-versus-host disease prophylaxis: single-institution analysis.

  Transplantation proceedings 20081201

• Tacrolimus with mini-methotrexate as prophylaxis for graft-versus-host disease in pediatric patients after allogeneic peripheral blood stem cell transplant or bone marrow transplant.

  Journal of pediatric hematology/oncology 20081201

• Early recognition of renal toxicity of high-dose methotrexate therapy: a case report.

  Journal of pediatric hematology/oncology 20081201

• Successful salvage chemotherapy for isolated central nervous system (CNS) relapse in Burkitt lymphoma: monocentric experience of 3 pediatric patients.

  Journal of pediatric hematology/oncology 20081201

• [Pulmonary resection in the management of gestational trophoblastic neoplasia: a clinical study].

  Zhonghua fu chan ke za zhi 20081201

• Population pharmacokinetics of high-dose methotrexate in Japanese adult patients with malignancies: a concurrent analysis of the serum and urine concentration data.

  Journal of clinical pharmacy and therapeutics 20081201

• [A retrospective analysis of clinical outcomes in 225 childhood with acute lymphoblastic leukemia].

  Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20081201

• Treatment of non-metastatic high-grade osteosarcoma (study of 30 cases treated with Scandinavian osteosarcoma protocol XIV and surgery).

  Prilozi 20081201

• [What's new in internal medicine?].

  Annales de dermatologie et de venereologie 20081201

• Vinflunine in the treatment of bladder cancer.

  Therapeutics and clinical risk management 20081201

• [Maxillofacial location of Burkitt's lymphoma in children treated at the University Hospital Center in Bamako, Mali: a 24-case series].

  Medecine tropicale : revue du Corps de sante colonial 20081201

• Adult Burkitt lymphoma: advances in diagnosis and treatment.

  Oncology (Williston Park, N.Y.) 20081130

• Design, synthesis, and in vitro activity of novel drug delivery systems containing tuftsin derivatives and methotrexate.

  Bioconjugate chemistry 20081119

• MACOP-B and involved-field radiotherapy is an effective and safe therapy for primary mediastinal large B cell lymphoma.

  International journal of radiation oncology, biology, physics 20081115

• Phase 2 trial of rituximab plus hyper-CVAD alternating with rituximab plus methotrexate-cytarabine for relapsed or refractory aggressive mantle cell lymphoma.

  Cancer 20081115

• Multiple toxic effects of low-dose methotrexate in a patient treated for psoriasis.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20081115

• Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.

  Journal of medicinal chemistry 20081113

• A novel electrophysiological model of chemotherapy-induced cognitive impairments in mice.

  Neuroscience 20081111

• Polyradiculopathy due to methotrexate-induced ebv-associated lymphoproliferative disorder.

  Neurology 20081111

• Systemic methotrexate to treat ectopic pregnancy does not affect ovarian reserve.

  Fertility and sterility 20081101

• The potential risk of neoadjuvant chemotherapy in breast cancer patients--results from a prospective randomized trial of the Austrian Breast and Colorectal Cancer Study Group (ABCSG-07).

  Breast cancer research and treatment 20081101

• Is risk of central nervous system (CNS) relapse related to adjuvant taxane treatment in node-positive breast cancer? Results of the CNS substudy in the intergroup Phase III BIG 02-98 Trial.

  Annals of oncology : official journal of the European Society for Medical Oncology 20081101

• Genetic determinants of methotrexate toxicity in rheumatoid arthritis patients: a study of polymorphisms affecting methotrexate transport and folate metabolism.

  European journal of clinical pharmacology 20081101

• Tight control and intensified COBRA combination treatment in early rheumatoid arthritis: 90% remission in a pilot trial.

  Annals of the rheumatic diseases 20081101

• Influence of methylene tetrahydrofolate reductase polymorphisms and coadministration of antimetabolites on toxicity after high dose methotrexate.

  European journal of haematology 20081101

• Determinants of cerebrospinal fluid arsenic concentration in patients with acute promyelocytic leukemia on oral arsenic trioxide therapy.

  Blood 20081101

• Increasing systemic exposure of methotrexate by active efflux mediated by multidrug resistance-associated protein 3 (mrp3/abcc3).

  The Journal of pharmacology and experimental therapeutics 20081101

• Pre-bled-young-rats in genotoxicity testing: a model for peripheral blood micronucleus assay.

  Regulatory toxicology and pharmacology : RTP 20081101

• Anthracyclines: the first generation of cytotoxic targeted agents? A possible dream.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20081101

• Type 1 receptor tyrosine kinase profiles identify patients with enhanced benefit from anthracyclines in the BR9601 adjuvant breast cancer chemotherapy trial.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20081101

• Plasmodium berghei: lack of antimalarial activity of an analogue of folate precursor, 2,4-diamino-6-hydroxymethylpteridine in a mouse model.

  Experimental parasitology 20081101

• RAPID3 (Routine Assessment of Patient Index Data 3), a rheumatoid arthritis index without formal joint counts for routine care: proposed severity categories compared to disease activity score and clinical disease activity index categories.

  The Journal of rheumatology 20081101

• Effect of transforming growth factor-alpha on enterocyte apoptosis is correlated with EGF receptor expression along the villus-crypt axis during methotrexate-induced intestinal mucositis in a rat.

  Apoptosis : an international journal on programmed cell death 20081101

• Marked increase of normal blast morphologically mimicking leukemic clone in acute lymphoblastic leukemia patient following G-CSF therapy.

  International journal of hematology 20081101

• Veno-occlusive disease of the liver during induction therapy for acute lymphoblastic leukemia.

  International journal of hematology 20081101

• Giant-cell arteritis.

  Current opinion in ophthalmology 20081101

• Treatment of erosive vulvovaginal lichen planus with methotrexate.

  The Australasian journal of dermatology 20081101

• Epstein Barr virus-associated primary CNS lymphomas in elderly patients on immunosuppressive medications.

  Journal of neuropathology and experimental neurology 20081101

• Treatment of rheumatoid arthritis with a Syk kinase inhibitor: a twelve-week, randomized, placebo-controlled trial.

  Arthritis and rheumatism 20081101

• A 75-year-old man with significant bleeding after transbronchial biopsy.

  Platelets 20081101

• Methotrexate monotherapy for high-risk gestational trophoblastic neoplasia after therapy with etoposide, methotrexate, and dactinomycin: a case report.

  American journal of obstetrics and gynecology 20081101

• Generalized pustulosis induced by adalimumab in a patient with rheumatoid arthritis - a therapeutic challenge.

  International journal of dermatology 20081101

• [A case of gastric cancer accompanied by disseminated carcinomatosis of bone marrow with DIC recovered by sequential therapy consisting of MTX and 5-FU].

  Gan to kagaku ryoho. Cancer & chemotherapy 20081101

• [Squamous cell carcinoma of the renal pelvis with elevation of G-CSF in the serum: a case report].

  Hinyokika kiyo. Acta urologica Japonica 20081101

• Therapeutic vignette: old and new drugs in mixed connective tissue disease.

  The Israel Medical Association journal : IMAJ 20081101

• [Metastases from urethelial carcinoma: role of chemotherapy].

  Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie 20081101

• [Study on adjuvant MTX-5-FU intraperitoneal chemotherapy for advanced gastric cancer].

  Gan to kagaku ryoho. Cancer & chemotherapy 20081101

• 'Strawberry gums' in sarcoidosis.

  Journal of the American Academy of Dermatology 20081101

• Evaluation of the interaction between nonsteroidal anti-inflammatory drugs and methotrexate using human organic anion transporter 3-transfected cells.

  European journal of pharmacology 20081031

• Low-dose methotrexate therapy for intravenous immunoglobulin-resistant Kawasaki disease.

  Yonsei medical journal 20081031

• NEAT: National Epirubicin Adjuvant Trial--toxicity, delivered dose intensity and quality of life.

  British journal of cancer 20081021

• Oral melphalan, prednisone, and thalidomide in elderly patients with multiple myeloma: updated results of a randomized controlled trial.

  Blood 20081015

• Del(6)(q22) and BCL6 rearrangements in primary CNS lymphoma are indicators of an aggressive clinical course.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20081010

• [Antirheumatic agents for treatment of rheumatoid arthritis].

  Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20081010

• Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.

  Journal of medicinal chemistry 20081009

• Practice of central nervous system prophylaxis and treatment in acute leukemias in Spain. Prospective registry study.

  Medicina clinica 20081004

• Long-term administration of a low-molecular-weight heparin contributed to successful treatment in a patient with primary mediastinal large B-cell lymphoma and venous thromboembolism.

  Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20081001

• Methotrexate-induced nitrosative stress may play a critical role in small intestinal damage in the rat.

  Archives of toxicology 20081001

• Assessment of the response to chemotherapy in gestational trophoblastic neoplasia with vaginal metastases.

  Archives of gynecology and obstetrics 20081001

• Interdisciplinary combined treatment of craniofacial osteosarcoma with neoadjuvant and adjuvant chemotherapy and excision of the tumour: a retrospective study.

  The British journal of oral & maxillofacial surgery 20081001

• Long-term follow-up of renal function after high-dose methotrexate treatment in children.

  Pediatric blood & cancer 20081001

• Improvements in clinical response between 12 and 24 weeks in patients with rheumatoid arthritis on etanercept therapy with or without methotrexate.

  Annals of the rheumatic diseases 20081001

• Histoplasmosis clinically imitating cutaneous malignancy.

  Journal of cutaneous pathology 20081001

• Comparison of antimetabolite drugs as corticosteroid-sparing therapy for noninfectious ocular inflammation.

  Ophthalmology 20081001

• Functional role of arginine 375 in transmembrane helix 6 of multidrug resistance protein 4 (MRP4/ABCC4).

  Molecular pharmacology 20081001

• Folinic acid administration following MTX as prophylaxis for GVHD in allogeneic HSCT centres in Australia and New Zealand.

  Bone marrow transplantation 20081001

• Pulse methotrexate versus pulse actinomycin D in the treatment of low-risk gestational trophoblastic neoplasia.

  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20081001

• Texas Red transport across rat and dogfish shark (Squalus acanthias) choroid plexus.

  American journal of physiology. Regulatory, integrative and comparative physiology 20081001

• Extracorporeal photopheresis for the treatment of Sézary syndrome using a novel treatment protocol.

  Journal of the American Academy of Dermatology 20081001

• Herpes zoster in patients taking TNFalpha antagonists for chronic inflammatory joint disease.

  Joint, bone, spine : revue du rhumatisme 20081001

• Ascendancy of weekly low-dose methotrexate in usual care of rheumatoid arthritis from 1980 to 2004 at two sites in Finland and the United States.

  Rheumatology (Oxford, England) 20081001

• Hepatitis C virus-related arthritis.

  Autoimmunity reviews 20081001

• Discordant perspectives of rheumatologists and patients on COBRA combination therapy in rheumatoid arthritis.

  Rheumatology (Oxford, England) 20081001

• The impact of histopathologic diagnosis on the proper management of testis neoplasms.

  Nature clinical practice. Oncology 20081001

• The safety of intraocular methotrexate in silicone-filled eyes.

  Retina (Philadelphia, Pa.) 20081001

• A 50-year-old man with burkitt lymphoma.

  Brain pathology (Zurich, Switzerland) 20081001

• Is it always therapeutically important to distinguish between Crohn's disease and ulcerative colitis?

  Inflammatory bowel diseases 20081001

• Lapatinib (Tykerb, GW572016) reverses multidrug resistance in cancer cells by inhibiting the activity of ATP-binding cassette subfamily B member 1 and G member 2.

  Cancer research 20081001

• An 'eruptive' variant of juvenile xanthogranuloma associated with langerhans cell histiocytosis.

  Journal of cutaneous pathology 20081001

• Heart-shaped lesion secondary to neurosarcoidosis.

  Archives of neurology 20081001

• Multicentric reticulohistiocytosis successfully treated with infliximab: an illustrative case and evaluation of cytokine expression supporting anti-tumor necrosis factor therapy.

  Archives of dermatology 20081001

• Intensive chemotherapy improved treatment outcome for Chinese children and adolescents with lymphoblastic lymphoma.

  International journal of clinical oncology 20081001

• Transfer of drug resistance genes into hematopoietic stem cells for marrow protection.

  The oncologist 20081001

• Neo-clinicians, clinical trials, and the reorganization of medical research in Paris hospitals after the Second World War: the trajectory of Jean Bernard.

  Medical history 20081001

• Practical issues in the management of low-risk gestational trophoblast tumors.

  The Journal of reproductive medicine 20081001

• Pharmacokinetic and pharmacodynamic properties of TRU-015, a CD20-directed small modular immunopharmaceutical protein therapeutic, in patients with rheumatoid arthritis: a Phase I, open-label, dose-escalation clinical study.

  Clinical therapeutics 20081001

• Treatment of relapsed or refractory aggressive non-hodgkin lymphoma with two ifosfamide-based regimens, IMVP and ICE.

  Journal of chemotherapy (Florence, Italy) 20081001

• Selective inhibitory effect of adenosine A1 receptor agonists on the proliferation of human tumor cell lines.

  Iranian biomedical journal 20081001

• Pustular psoriasis following treatment of rheumatoid arthritis with TNF-alpha inhibitors.

  Journal of drugs in dermatology : JDD 20081001

• [Effects of methopterin on osteoclasts and study of its mechanism of action].

  Yao xue xue bao = Acta pharmaceutica Sinica 20081001

• Potent dual thymidylate synthase and dihydrofolate reductase inhibitors: classical and nonclassical 2-amino-4-oxo-5-arylthio-substituted-6-methylthieno[2,3-d]pyrimidine antifolates.

  Journal of medicinal chemistry 20080925

• Review article: treatment algorithms to maximize remission and minimize corticosteroid dependence in patients with inflammatory bowel disease.

  Alimentary pharmacology & therapeutics 20080915

• A prospective clinicopathologic study of dose-modified CODOX-M/IVAC in patients with sporadic Burkitt lymphoma defined using cytogenetic and immunophenotypic criteria (MRC/NCRI LY10 trial).

  Blood 20080915

• Short hairpin RNA targeted to dihydrofolate reductase enhances the immunoglobulin G expression in gene-amplified stable Chinese hamster ovary cells.

  Vaccine 20080908

• Level of radiographic damage and radiographic progression are determinants of physical function: a longitudinal analysis of the TEMPO trial.

  Annals of the rheumatic diseases 20080901

• Characteristics and medical management of patients with rheumatoid arthritis and ankylosing spondylitis.

  Clinical rheumatology 20080901

• Polymorphisms in folate-related genes: association with side effects of high-dose methotrexate in childhood acute lymphoblastic leukemia.

  Leukemia 20080901

• [Elevated liver enzymes in rheumatoid arthritis : differential diagnostic considerations based on a case report].

  Zeitschrift fur Rheumatologie 20080901

• Effects of chemotherapeutic agents 5-fluorouracil and methotrexate alone and combined in a mouse model of learning and memory.

  Psychopharmacology 20080901

• A dual role of p21waf1/cip1 gene in apoptosis of HEp-2 treated with cisplatin or methotrexate.

  Cancer gene therapy 20080901

• The use of local surface properties for molecular superimposition.

  Journal of molecular modeling 20080901

• mTOR inhibitors are synergistic with methotrexate: an effective combination to treat acute lymphoblastic leukemia.

  Blood 20080901

• A novel loss-of-function mutation in the proton-coupled folate transporter from a patient with hereditary folate malabsorption reveals that Arg 113 is crucial for function.

  Blood 20080901

• Enhanced MRI in early undifferentiated oligoarthritis of the knee joints: improvements already visible after 2 months of DMARDs treatment.

  Clinical rheumatology 20080901

• The impact of methylenetetrahydrofolate reductase (MTHFR) C677T gene polymorphism on transplant-related variables after allogeneic hematopoietic cell transplantation in patients receiving MTX as GVHD prophylaxis.

  Bone marrow transplantation 20080901

• Potent protective effect of apricot and beta-carotene on methotrexate-induced intestinal oxidative damage in rats.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080901

• Adjunctive anakinra in patients with active rheumatoid arthritis despite methotrexate, or leflunomide, or cyclosporin-A monotherapy: a 48-week, comparative, prospective study.

  Rheumatology (Oxford, England) 20080901

• Extremely slow methotrexate elimination in a patient with t(9;22) positive acute lymphoblastic leukemia treated with imatinib.

  American journal of hematology 20080901

• Leishmania donovani pteridine reductase 1: biochemical properties and structure-modeling studies.

  Experimental parasitology 20080901

• Tolerability of methotrexate and leflunomide combination therapy for inflammatory arthritis in routine clinical practice: results of a four-centre study.

  Rheumatology (Oxford, England) 20080901

• Adjuvant methotrexate, vinblastine, adriamycin, and cisplatin chemotherapy has potential to prevent recurrence of bladder tumors after surgical removal of upper urinary tract transitional cell carcinoma.

  International journal of urology : official journal of the Japanese Urological Association 20080901

• Intrathecal trastuzumab (Herceptin) and methotrexate for meningeal carcinomatosis in HER2-overexpressing metastatic breast cancer: a case report.

  Anti-cancer drugs 20080901

• Trastuzumab-resistant breast cancer cells remain sensitive to the auger electron-emitting radiotherapeutic agent 111In-NLS-trastuzumab and are radiosensitized by methotrexate.

  Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20080901

• Optimization of iontophoretic parameters for the transdermal delivery of methotrexate.

  Drug delivery 20080901

• Managing reduced methotrexate clearance in a patient with a heterozygous methylenetetrahydrofolate reductase gene polymorphism.

  Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners 20080901

• Hypocomplementemic urticarial vasculitis with Jaccoud's arthropathy and valvular heart disease: case report and review of the literature.

  Lupus 20080901

• Chikungunya virus aches and pains: an emerging challenge.

  Arthritis and rheumatism 20080901

• High-dose methotrexate: insecure rationale: take 2.

  Journal of pediatric hematology/oncology 20080901

• [Benefits and risks of immunosuppression in chronic inflammatory bowel diseases].

  Deutsche medizinische Wochenschrift (1946) 20080901

• Critical coronary artery stenosis and aortitis in a patient with relapsing polychondritis.

  The Journal of rheumatology 20080901

• Umbilical cord-blood transplantations from unrelated donors in patients with inherited metabolic diseases: Single-institute experience.

  Pediatric transplantation 20080901

• On-line stacking capillary electrophoresis for analysis of methotrexate and its eight metabolites in whole blood.

  Electrophoresis 20080901

• [Combination therapy consisting of gemcitabine, docetaxel and carboplatin as a second-line chemotherapy for patients with MVAC-treated metastatic urothelial carcinoma].

  Hinyokika kiyo. Acta urologica Japonica 20080901

• Synthesis and discovery of high affinity folate receptor-specific glycinamide ribonucleotide formyltransferase inhibitors with antitumor activity.

  Journal of medicinal chemistry 20080828

• The effect of 5-alkyl modification on the biological activity of pyrrolo[2,3-d]pyrimidine containing classical and nonclassical antifolates as inhibitors of dihydrofolate reductase and as antitumor and/or antiopportunistic infection agents.

  Journal of medicinal chemistry 20080814

• New insight into epirubicin cardiac toxicity: competing risks analysis of 1097 breast cancer patients.

  Journal of the National Cancer Institute 20080806

• Everolimus in patients with rheumatoid arthritis receiving concomitant methotrexate: a 3-month, double-blind, randomised, placebo-controlled, parallel-group, proof-of-concept study.

  Annals of the rheumatic diseases 20080801

• Efficacy and safety of abatacept or infliximab vs placebo in ATTEST: a phase III, multi-centre, randomised, double-blind, placebo-controlled study in patients with rheumatoid arthritis and an inadequate response to methotrexate.

  Annals of the rheumatic diseases 20080801

• Early treatment reduces the cardiovascular risk factors in newly diagnosed rheumatoid arthritis patients.

  Seminars in arthritis and rheumatism 20080801

• Mycophenolate mofetil after methotrexate failure or intolerance in the treatment of scleritis and uveitis.

  Ophthalmology 20080801

• Genetic variation in efflux transporters influences outcome to methotrexate therapy in patients with psoriasis.

  The Journal of investigative dermatology 20080801

• Safety and efficacy of etanercept in children with juvenile idiopathic arthritis below the age of 4 years.

  Rheumatology international 20080801

• Clinical impact of the methotrexate resistance-associated genes C-MYC and dihydrofolate reductase (DHFR) in high-grade osteosarcoma.

  Annals of oncology : official journal of the European Society for Medical Oncology 20080801

• Extracapsular tumor spread and the risk of local, axillary and supraclavicular recurrence in node-positive, premenopausal patients with breast cancer.

  Annals of oncology : official journal of the European Society for Medical Oncology 20080801

• Interaction between methotrexate and omeprazole in an adolescent with leukemia: a case report.

  Pharmacy world & science : PWS 20080801

• Targeted drug delivery by in vivo coupling to endogenous albumin: an albumin-binding prodrug of methotrexate (MTX) is better than MTX in the treatment of murine collagen-induced arthritis.

  Annals of the rheumatic diseases 20080801

• Leflunomide (Arava) is a useful DMARD in Indian (Asian) patients: a clinic-based observational study of 1-year treatment.

  Clinical rheumatology 20080801

• Approaches to the treatment of early rheumatoid arthritis with disease-modifying antirheumatic drugs.

  British journal of clinical pharmacology 20080801

• Polymorphisms within the adenosine receptor 2a gene are associated with adverse events in RA patients treated with MTX.

  Rheumatology (Oxford, England) 20080801

• Pure motor lumbosacral radiculopathy after intrathecal chemotherapy.

  European journal of neurology 20080801

• Oral mucosal lesions, microbial changes, and taste disturbances induced by adjuvant chemotherapy in breast cancer patients.

  Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20080801

• Identification of a methotrexate-binding peptide from a T7 phage display screen using a QCM device.

  Bioorganic & medicinal chemistry 20080801

• Pharmacogenetic study of 5,10-methylenetetrahydrofolate reductase C677T and thymidylate synthase 3R/2R gene polymorphisms and methotrexate-related toxicity in Chinese Han patients with inflammatory arthritis.

  Annals of the rheumatic diseases 20080801

• Differential effect on symptoms treated with traditional Chinese medicine and western combination therapy in RA patients.

  Complementary therapies in medicine 20080801

• Sirolimus, tacrolimus, and low-dose methotrexate as graft-versus-host disease prophylaxis in related and unrelated donor reduced-intensity conditioning allogeneic peripheral blood stem cell transplantation.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20080801

• Re: High-dose compared with intermediate-dose methotrexate in children with a first relapse of acute lymphatic leukemia.

  Blood 20080801

• Treatment of pediatric acute lymphoblastic leukemia.

  Haematologica 20080801

• Azathioprine in multiple sclerosis.

  Mini reviews in medicinal chemistry 20080801

• [Is the guideline, 'Management of early rheumatoid arthritis,' being followed in a rheumatism center?].

  Deutsche medizinische Wochenschrift (1946) 20080801

• Chemoradiotherapy laryngeal preservation for advanced hypopharyngeal cancer.

  Japanese journal of clinical oncology 20080801

• Gastric phenotype signet-ring cell carcinoma of the stomach with multiple bone metastases effectively treated with sequential methotrexate and 5-fluorouracil.

  International journal of clinical oncology 20080801

• Schnitzler syndrome successfully treated with methotrexate.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20080801

• Effects of methotrexate use in a patient with rheumatoid arthritis and multiple sclerosis.

  Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20080801

• Development of autoimmune diseases after vaccination.

  Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20080801

• Immune reconstitution during maintenance therapy in children with acute lymphoblastic leukemia, relation to co-existing infection.

  Hematology (Amsterdam, Netherlands) 20080801

• [Graft-versus-host disease: friend or foe?].

  [Rinsho ketsueki] The Japanese journal of clinical hematology 20080801

• [Current treatment of systemic sclerosis. Part I. Immunosuppressive treatment].

  Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20080801

• Development of novel magnetic nano-carriers for high-performance affinity purification.

  Colloids and surfaces. B, Biointerfaces 20080715

• Gene expression profiles of murine fatty liver induced by the administration of methotrexate.

  Toxicology 20080710

• Concurrent cyclophosphamide, methotrexate, and 5-fluorouracil chemotherapy and radiotherapy for early breast carcinoma.

  International journal of radiation oncology, biology, physics 20080701

• The treatment and prognosis of dermatomyositis: an updated review.

  Journal of the American Academy of Dermatology 20080701

• Rituximab improves the efficacy of high-dose chemotherapy with autograft for high-risk follicular and diffuse large B-cell lymphoma: a multicenter Gruppo Italiano Terapie Innnovative nei linfomi survey.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080701

• In vitro and in vivo anti-tumoral activities of imidazo[1,2-a]quinoxaline, imidazo[1,5-a]quinoxaline, and pyrazolo[1,5-a]quinoxaline derivatives.

  Bioorganic & medicinal chemistry 20080701

• Serum levels of NFkappaB and pro-inflammatory cytokines following administration of mucotoxic drugs.

  Cancer biology & therapy 20080701

• Amiodarone modulates pharmacokinetics of low-dose methotrexate in rats.

  Biopharmaceutics & drug disposition 20080701

• Altered expression of methylenetetrahydrofolate reductase modifies response to methotrexate in mice.

  Pharmacogenetics and genomics 20080701

• 2-tier bacterial and in vitro selection of active and methotrexate-resistant variants of human dihydrofolate reductase.

  Journal of biomolecular screening 20080701

• Lessons from a time capsule: evolution, not revolution, in therapy for advanced non-small-cell lung cancer.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080701

• Late cardiac effects of adjuvant radiotherapy and chemotherapy in early breast cancer.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080701

• [Primary cutaneous manifestation of Wegener's granulomatosis].

  Deutsche medizinische Wochenschrift (1946) 20080701

• Drug use and toxicity in psoriatic disease: focus on methotrexate.

  The Journal of rheumatology 20080701

• Methotrexate and leucovorin double-modulated 5-fluorouracil combined with cisplatin (MPFL) in metastatic/recurrent head and neck cancer.

  Journal of the Chinese Medical Association : JCMA 20080701

• Diagnosis and treatment of high-risk metastatic gestational trophoblastic neoplasia in Hungary.

  The Journal of reproductive medicine 20080701

• COX-2 expression correlates with survival in patients with osteosarcoma lung metastases.

  Journal of pediatric hematology/oncology 20080701

• Severe neurotoxicities in a case of Charcot-Marie-Tooth disease type 2 caused by vincristine for acute lymphoblastic leukemia.

  Journal of pediatric hematology/oncology 20080701

• Caffeic acid phenethyl ester modulates methotrexate-induced oxidative stress in testes of rat.

  Human & experimental toxicology 20080701

• Early-onset pancytopenia and skin ulcer following low-dose methotrexate therapy.

  Human & experimental toxicology 20080701

• Levoleucovorin.

  Oncology (Williston Park, N.Y.) 20080701

• Synergistic immunosuppressive effect of anti-TNF combined with methotrexate on antibody responses to the 23 valent pneumococcal polysaccharide vaccine.

  Vaccine 20080625

• Osteosarcoma: the same old drugs or more?

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080620

• Conventional and diffusion-weighted MRI findings of methotrexate related sub-acute neurotoxicity.

  Journal of the neurological sciences 20080615

• Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).

  Journal of medicinal chemistry 20080612

• A single center experience of methotrexate in the treatment of Crohn's disease and ulcerative colitis: a case for subcutaneous administration.

  Journal of gastroenterology and hepatology 20080601

• Phase 2B trial of aminopterin in multiagent therapy for children with newly diagnosed acute lymphoblastic leukemia.

  Cancer chemotherapy and pharmacology 20080601

• Aggressive combination therapy with intra-articular glucocorticoid injections and conventional disease-modifying anti-rheumatic drugs in early rheumatoid arthritis: second-year clinical and radiographic results from the CIMESTRA study.

  Annals of the rheumatic diseases 20080601

• Treatment of B-cell lymphoma with LMB modified protocols in Africa--report of the French-African Pediatric Oncology Group (GFAOP).

  Pediatric blood & cancer 20080601

• Histological analysis of synovium in cases of effect attenuation associated with infliximab therapy in rheumatoid arthritis.

  Clinical rheumatology 20080601

• Cardiac engagement in multicentric reticulohistiocytosis: report of a case with fatal outcome and literature review.

  Internal and emergency medicine 20080601

• The Memorial Sloan Kettering Cancer Center experience with outpatient administration of high dose methotrexate with leucovorin rescue.

  Pediatric blood & cancer 20080601

• Are Thymidylate synthase and Methylene tetrahydrofolate reductase genes linked with methotrexate response (efficacy, toxicity) in Indian (Asian) rheumatoid arthritis patients?

  Clinical rheumatology 20080601

• Use of methotrexate in refractory Crohn's disease: the Edinburgh experience.

  Inflammatory bowel diseases 20080601

• Inhibition of c-Myc down-regulation by sustained extracellular signal-regulated kinase activation prevents the antimetabolite methotrexate- and gemcitabine-induced differentiation in non-small-cell lung cancer cells.

  Molecular pharmacology 20080601

• Decreased risk of acute graft-versus-host disease following allogeneic hematopoietic stem cell transplantation in patients with the 5,10-methylenetetrahydrofolate reductase 677TT genotype.

  International journal of hematology 20080601

• Results of the first randomized multicentre trial on childhood acute lymphoblastic leukaemia in Russia.

  Leukemia 20080601

• Excellent survival following two courses of COPAD chemotherapy in children and adolescents with resected localized B-cell non-Hodgkin's lymphoma: results of the FAB/LMB 96 international study.

  British journal of haematology 20080601

• Low-dose prednisolone in rheumatoid arthritis: adverse effects of various disease modifying antirheumatic drugs.

  The Journal of rheumatology 20080601

• Withdrawal of immunosuppression in Crohn's disease treated with scheduled infliximab maintenance: a randomized trial.

  Gastroenterology 20080601

• ACOG Practice Bulletin No. 94: Medical management of ectopic pregnancy.

  Obstetrics and gynecology 20080601

• A phase II study of sequential methotrexate and 5-fluorouracil chemotherapy in previously treated gastric cancer: a report from the Gastrointestinal Oncology Group of the Japan Clinical Oncology Group, JCOG 9207 trial.

  Japanese journal of clinical oncology 20080601

• Extranodal lymphoma: a reappraisal.

  Annals of oncology : official journal of the European Society for Medical Oncology 20080601

• Clinical pharmacology of gold.

  Inflammopharmacology 20080601

• [Association between mthfr gene polymorphisms and toxicity of HDMTX chemotherapy in acute lymphocytic leukemia].

  Zhongguo shi yan xue ye xue za zhi 20080601

• Do safe and effective treatment options exist for patients with active pemphigus vulgaris who plan conception and pregnancy?

  Archives of dermatology 20080601

• Adjuvant dose-dense sequential chemotherapy with epirubicin, CMF and weekly paclitaxel in patients with resected high-risk breast cancer: a Hellenic Cooperative Oncology Group (HeCOG) study.

  Cancer investigation 20080601

• Case files of the New York City Poison Control Center: antidotal strategies for the management of methotrexate toxicity.

  Journal of medical toxicology : official journal of the American College of Medical Toxicology 20080601

• Clinical and radiological features of brain neurotoxicity caused by antitumor and immunosuppressant treatments.

  Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20080601

• Low dose methotrexate therapy is effective in late-onset atopic dermatitis and idiopathic eczema.

  The Israel Medical Association journal : IMAJ 20080601

• Differential in vitro inhibitory effects of anticancer drugs on tumor-associated carbonic anhydrase isozymes CA IX and CA XII.

  Methods and findings in experimental and clinical pharmacology 20080601

• [Clinical randomized study of bee-sting therapy for rheumatoid arthritis].

  Zhen ci yan jiu = Acupuncture research 20080601

• Curcumin attenuates methotraxate-induced hepatic oxidative damage in rats.

  Journal of the Egyptian National Cancer Institute 20080601

• [Chemotherapy and renal toxicity].

  Bulletin du cancer 20080528

• Treatment options for muscle-invasive urothelial cancer for patients who were not eligible for cystectomy or neoadjuvant chemotherapy with methotrexate, vinblastine, doxorubicin, and cisplatin: report of Southwest Oncology Group Trial 8733.

  Cancer 20080515

• FBXW7 and DNA copy number instability.

  Breast cancer research and treatment 20080501

• Aberrant phenotype of plasmacytoid monocytes in acute myeloid leukemia.

  American journal of hematology 20080501

• Delayed leukoencephalopathy with stroke-like presentation in chemotherapy recipients.

  Journal of neurology, neurosurgery, and psychiatry 20080501

• Factorial randomised controlled trial of glucocorticoids and combination disease modifying drugs in early rheumatoid arthritis.

  Annals of the rheumatic diseases 20080501

• Self-assembled, fluorescent polymeric micelles of a graft copolymer containing carbazole for thermo-controlled drug delivery in vitro.

  Journal of biomedical materials research. Part B, Applied biomaterials 20080501

• Postoperative dose-dense sequential chemotherapy with epirubicin, paclitaxel and CMF in patients with high-risk breast cancer: safety analysis of the Hellenic Cooperative Oncology Group randomized phase III trial HE 10/00.

  Annals of oncology : official journal of the European Society for Medical Oncology 20080501

• Intrathecal chemotherapy for refractory disseminated medulloblastoma.

  Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 20080501

• Idiopathic hypertrophic cranial pachymeningitis treated by oral methotrexate: a case report and review of literature.

  Rheumatology international 20080501

• Weekly docetaxel versus CMF as adjuvant chemotherapy for elderly breast cancer patients: safety data from the multicentre phase 3 randomised ELDA trial.

  Critical reviews in oncology/hematology 20080501

• Comparison of four regimens of misoprostol after methotrexate for early abortion.

  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20080501

• Triple-negative high-risk breast cancer derives particular benefit from dose intensification of adjuvant chemotherapy: results of WSG AM-01 trial.

  Annals of oncology : official journal of the European Society for Medical Oncology 20080501

• Multimodality treatment of osteosarcoma: radiation in a high-risk cohort.

  Pediatric blood & cancer 20080501

• Enhanced systemic availability of methotrexate in the presence of morin in rats.

  Biopharmaceutics & drug disposition 20080501

• Effect of folate derivatives on the activity of antifolate drugs used against malaria and cancer.

  Parasitology research 20080501

• Phase I study of dexamethasone, methotrexate, ifosfamide, L-asparaginase, and etoposide (SMILE) chemotherapy for advanced-stage, relapsed or refractory extranodal natural killer (NK)/T-cell lymphoma and leukemia.

  Cancer science 20080501

• Evidence from nonrandomized studies: a case study on the estimation of causal effects.

  American journal of epidemiology 20080501

• Elucidating the germination transcriptional program using small molecules.

  Plant physiology 20080501

• Sirolimus in combination with cyclosporine or tacrolimus plus methotrexate for prevention of graft-versus-host disease following hematopoietic cell transplantation from unrelated donors.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20080501

• Results of treatment of 112 cases of primary CNS lymphoma.

  Japanese journal of clinical oncology 20080501

• Guidelines of care for the management of psoriasis and psoriatic arthritis: Section 1. Overview of psoriasis and guidelines of care for the treatment of psoriasis with biologics.

  Journal of the American Academy of Dermatology 20080501

• Progression of joint damage in early rheumatoid arthritis: association with HLA-DRB1, rheumatoid factor, and anti-citrullinated protein antibodies in relation to different treatment strategies.

  Arthritis and rheumatism 20080501

• Triple therapy in early active rheumatoid arthritis: a randomized, single-blind, controlled trial comparing step-up and parallel treatment strategies.

  Arthritis and rheumatism 20080501

• MDM2 regulates dihydrofolate reductase activity through monoubiquitination.

  Cancer research 20080501

• Influence of MTHFR and RFC1 polymorphisms on toxicities during maintenance chemotherapy for childhood acute lymphoblastic leukemia or lymphoma.

  Journal of pediatric hematology/oncology 20080501

• Intravenous immunoglobulin in the treatment of severe methotrexate-induced acral erythema.

  Journal of pediatric hematology/oncology 20080501

• [Treatment of advanced maxillary sinus squamous carcinoma: an analysis of 92 cases].

  Ai zheng = Aizheng = Chinese journal of cancer 20080501

• [A case of advanced gastric cancer with peritoneal metastasis successfully treated over 19 months with postoperative chemotherapy after non-curative surgery].

  Gan to kagaku ryoho. Cancer & chemotherapy 20080501

• A retrospective analysis of patients with bullous pemphigoid treated with methotrexate.

  Archives of dermatology 20080501

• Kaposi's sarcoma resolves after sirolimus therapy in a patient with pemphigus vulgaris.

  Archives of dermatology 20080501

• The potential use of methotrexate in the treatment of falciparum malaria: in vitro assays against sensitive and multidrug-resistant falciparum strains.

  Japanese journal of infectious diseases 20080501

• [Outpatient chemotherapy and oncology network : Onco Pays-de-la-Loire experiment].

  Bulletin du cancer 20080501

• Mucocutaneous ulcerations secondary to methotrexate.

  Cutis 20080501

• Effects of purified micronized flavonoid fraction (Detralex) on prophylactic treatment of adjuvant arthritis with methotrexate in rats.

  The Israel Medical Association journal : IMAJ 20080501

• Prophylaxis of central nervous system leukemia: a case of chronic myeloid leukemia with lymphoid blast crisis treated with imatinib mesylate.

  World journal of pediatrics : WJP 20080501

• What constitutes 'improved prognosis'?

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080420

• Anterior lumbosacral polyradiculopathy after intrathecal administration of methotrexate.

  Journal of the neurological sciences 20080415

• Role of proline 1150 in functional interactions between the membrane spanning domains and nucleotide binding domains of the MRP1 (ABCC1) transporter.

  Biochemical pharmacology 20080415

• Development of a chemical screening system using aqueorin-fused protein.

  Biochemical and biophysical research communications 20080411

• Comparison of the results of the treatment of adolescents and young adults with standard-risk acute lymphoblastic leukemia with the Programa Español de Tratamiento en Hematología pediatric-based protocol ALL-96.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080410

• Pemetrexed, a multitargeted antifolate drug, demonstrates lower efficacy in comparison to methotrexate against osteosarcoma cell lines.

  Pediatric blood & cancer 20080401

• Methotrexate combined with isoniazid treatment for latent tuberculosis is well tolerated in patients with rheumatoid arthritis: experience from an urban arthritis clinic.

  Annals of the rheumatic diseases 20080401

• Post-transplant hepatosplenic T-cell lymphoma successfully treated with HyperCVAD regimen.

  American journal of hematology 20080401

• Lipomembranous panniculitis in a patient with acute leukemia induced by chemotherapy.

  Leukemia research 20080401

• Role of ursodeoxycholic acid in prevention of methotrexate-induced liver toxicity.

  Digestive diseases and sciences 20080401

• Neurochemical markers of brain damage in cerebrospinal fluid during induction treatment of acute lymphoblastic leukemia in children.

  Pediatric blood & cancer 20080401

• Responsiveness to anti-tumour necrosis factor alpha therapy is related to pre-treatment tissue inflammation levels in rheumatoid arthritis patients.

  Annals of the rheumatic diseases 20080401

• [Management of cytomegalovirus infections in patients treated with immunosuppressive drugs for chronic inflammatory diseases].

  La Revue de medecine interne 20080401

• Multiple cutaneous relapses in an adolescent in anaplastic large cell lymphoma diagnosed by FNAC.

  Cytopathology : official journal of the British Society for Clinical Cytology 20080401

• DNA variants in the dihydrofolate reductase gene and outcome in childhood ALL.

  Blood 20080401

• The effect of folic acid supplementation on the pharmacokinetics and pharmacodynamics of oral methotrexate during the remission-induction period of treatment for moderate-to-severe plaque psoriasis.

  European journal of clinical pharmacology 20080401

• Cyclosporin, methotrexate and prednisolone for graft-versus-host disease prophylaxis in allogeneic peripheral blood progenitor cell transplants.

  Bone marrow transplantation 20080401

• Role of lysine 411 in substrate carboxyl group binding to the human reduced folate carrier, as determined by site-directed mutagenesis and affinity inhibition.

  Molecular pharmacology 20080401

• Avonex Combination Trial in relapsing--remitting MS: rationale, design and baseline data.

  Multiple sclerosis (Houndmills, Basingstoke, England) 20080401

• Methotrexate: prescribing and monitoring practices among the consultant membership of the British Association of Dermatologists.

  The British journal of dermatology 20080401

• Influence of physiologic hormonal modification and of hormonal treatment in a patient with a history of migraine with aura.

  The journal of headache and pain 20080401

• p27 and Skp2 immunoreactivity and its clinical significance with endocrine and chemo-endocrine treatments in node-negative early breast cancer.

  Annals of oncology : official journal of the European Society for Medical Oncology 20080401

• Safe adalimumab therapy for rheumatoid arthritis in a patient with pre-existing multiple myeloma.

  Nature clinical practice. Rheumatology 20080401

• Immune tolerance induction to enzyme-replacement therapy by co-administration of short-term, low-dose methotrexate in a murine Pompe disease model.

  Clinical and experimental immunology 20080401

• Reduced folate carrier polymorphism determines methotrexate uptake by B cells and CD4+ T cells.

  Rheumatology (Oxford, England) 20080401

• Common polymorphisms in the folate pathway predict efficacy of combination regimens containing methotrexate and sulfasalazine in early rheumatoid arthritis.

  The Journal of rheumatology 20080401

• Case report: Second primary small cell carcinoma of the trachea in a breast cancer survivor: a case report and literature review.

  The British journal of radiology 20080401

• Sub-acute demyelinating neuropathy associated with an NK/T cell lymphoma.

  Journal of neurology, neurosurgery, and psychiatry 20080401

• A linear orofacial macule.

  The American Journal of dermatopathology 20080401

• Methotrexate (MTX) pathway gene polymorphisms and their effects on MTX toxicity in Caucasian and African American patients with rheumatoid arthritis.

  The Journal of rheumatology 20080401

• Anemia is a significant prognostic factor in local relapse-free survival of premenopausal primary breast cancer patients receiving adjuvant cyclophosphamide/methotrexate/5-fluorouracil chemotherapy.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20080401

• Loss of retinoblastoma tumor suppressor protein makes human breast cancer cells more sensitive to antimetabolite exposure.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20080401

• Identity of single-nucleotide polymorphisms used in a clinical pharmacogenetic model to predict the efficacy of methotrexate monotherapy: comment on the article by Wessels et al.

  Arthritis and rheumatism 20080401

• Methotrexate-induced alterations in beta-oxidation correlate with cognitive abilities in children with acute lymphoblastic leukemia.

  Biological research for nursing 20080401

• Favourable outcomes in children with diffuse large B-cell lymphoma treated by a short-term ALL-like regimen: a report on the NHL960 study from the Japanese Childhood Cancer and Leukemia Study Group.

  Leukemia & lymphoma 20080401

• Outcome of childhood B-cell non-Hodgkin lymphoma and B-cell acute lymphoblastic leukemia treated with the Tokyo Children's Cancer Study Group NHL B9604 protocol.

  Leukemia & lymphoma 20080401

• Pharmacogenomics of methotrexate in rheumatoid arthritis: does race make a difference?

  The Journal of rheumatology 20080401

• Primary parotid non-Hodgkin lymphoma in an infant.

  Journal of pediatric surgery 20080401

• Uterine choriocarcinoma accompanied by an extremely high human chorionic gonadotropin level and thyrotoxicosis.

  The journal of obstetrics and gynaecology research 20080401

• In vivo response to methotrexate forecasts outcome of acute lymphoblastic leukemia and has a distinct gene expression profile.

  PLoS medicine 20080401

• A case of primary hepatic Burkitt's lymphoma.

  The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi 20080401

• Drug-induced interstitial pneumonia.

  Prescrire international 20080401

• [Primary central nervous system lymphoma in an immunocompetent patient: report of a case].

  Revista medica de Chile 20080401

• [Effects of high-dose methotrexate therapy on intestinal bacterial flora in children with acute lymphoblastic leukemia].

  Zhonghua er ke za zhi = Chinese journal of pediatrics 20080401

• Effect of folic acid on methotrexate induction of sulfotransferases in rats.

  Drug metabolism letters 20080401

• Interactions between treatment and continuous covariates: a step toward individualizing therapy.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080320

• Chemoendocrine compared with endocrine adjuvant therapies for node-negative breast cancer: predictive value of centrally reviewed expression of estrogen and progesterone receptors--International Breast Cancer Study Group.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080320

• Cyclin D1 expression in breast cancer patients receiving adjuvant tamoxifen-based therapy.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20080315

• Late cardiac effects of adjuvant chemotherapy in breast cancer survivors treated on Southwest Oncology Group protocol s8897.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080310

• Parotid acinar cell carcinoma in a long-term survivor of childhood acute lymphoblastic leukemia.

  Pediatric blood & cancer 20080301

• Thyroid involvement with Langerhans cell histiocytosis in a 3-year-old male.

  Pediatric blood & cancer 20080301

• Brainstem primitive neuroectodermal tumors (bstPNET): results of treatment with intensive induction chemotherapy followed by consolidative chemotherapy with autologous hematopoietic cell rescue.

  Pediatric blood & cancer 20080301

• Osteosarcoma metastatic to the kidney and iatrogenic hemorrhage.

  Pediatric blood & cancer 20080301

• EBV+ lymphoproliferative disease following prolonged chemotherapy for refractory LCH.

  Pediatric blood & cancer 20080301

• Fatal adenovirus hepatitis during maintenance therapy for childhood acute lymphoblastic leukemia.

  Pediatric blood & cancer 20080301

• Early-onset sarcoidosis mimicking refractory cutaneous histiocytosis.

  Pediatric blood & cancer 20080301

• Triple intrathecal therapy without cranial irradiation for central nervous system preventive therapy in childhood acute lymphoblastic leukemia.

  Pediatric blood & cancer 20080301

• Phase III randomized multicenter study on the effects of adjuvant CMF in patients with node-negative, rapidly proliferating breast cancer: twelve-year results and retrospective subgroup analysis.

  Breast cancer research and treatment 20080301

• Impairments in antifolate transport are common in retinoblastoma tumor samples.

  Pediatric blood & cancer 20080301

• Hydroxy fatty acid based polyanhydride as drug delivery system: synthesis, characterization, in vitro degradation, drug release, and biocompatibility.

  Journal of biomedical materials research. Part A 20080301

• Reliability and sensitivity to change of the Simple Erosion Narrowing Score compared with the Sharp-van der Heijde method for scoring radiographs in rheumatoid arthritis.

  Annals of the rheumatic diseases 20080301

• Overcoming drug resistance induced by P-glycoprotein on lymphocytes in patients with refractory rheumatoid arthritis.

  Annals of the rheumatic diseases 20080301

• Folinic acid attenuates methotrexate chemotherapy-induced damages on bone growth mechanisms and pools of bone marrow stromal cells.

  Journal of cellular physiology 20080301

• Idiopathic hypertrophic cranial pachymeningitis causing progressive polyneuropathies in a child.

  European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20080301

• Absent immunoglobulins in HIV-related Burkitt lymphoma/leukaemia.

  Annals of hematology 20080301

• Low-dose MTX for the treatment of acute and chronic graft-versus-host disease in children.

  Bone marrow transplantation 20080301

• Recent insights in the pharmacological actions of methotrexate in the treatment of rheumatoid arthritis.

  Rheumatology (Oxford, England) 20080301

• Functional characterization of PCFT/HCP1 as the molecular entity of the carrier-mediated intestinal folate transport system in the rat model.

  American journal of physiology. Gastrointestinal and liver physiology 20080301

• Leflunomide as adjuvant treatment of dermatomyositis.

  Journal of the American Academy of Dermatology 20080301

• Treatment of psoriatic arthritis and rheumatoid arthritis with disease modifying drugs -- comparison of drugs and adverse reactions.

  The Journal of rheumatology 20080301

• Cholesterol crescents and plates in shoulder effusion of a rheumatoid patient.

  Rheumatology (Oxford, England) 20080301

• Kidney disease in RA patients: prevalence and implication on RA-related drugs management: the MATRIX study.

  Rheumatology (Oxford, England) 20080301

• Peripheral blood versus bone marrow as a source of hematopoietic stem cells for allogeneic transplantation in children with class I and II beta thalassemia major.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20080301

• Methotrexate-induced and Epstein-Barr virus-associated B-cell lymphoma of the spine: MR and PET/CT imaging.

  Clinical nuclear medicine 20080301

• Mechanisms of antifolate resistance and methotrexate efficacy in leukemia cells.

  Leukemia & lymphoma 20080301

• Establishment and characteristics of two syngeneic human osteosarcoma cell lines from primary tumor and skip metastases.

  Acta pharmacologica Sinica 20080301

• Intravitreal methotrexate for treating vitreoretinal lymphoma: 10 years of experience.

  The British journal of ophthalmology 20080301

• A fatal outcome in a patient with glioblastoma multiforme after receiving high-dose methotrexate.

  Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners 20080301

• Treatment trial of multicentric reticulohistiocytosis with a combination of predonisolone, methotrexate and alendronate.

  The Journal of dermatology 20080301

• Isolated lymphoma of the anterior visual pathway diagnosed by optic nerve biopsy.

  Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society 20080301

• Recurrent head and neck cancer: current treatment and future prospects.

  Expert review of anticancer therapy 20080301

• [Good results of early medicinal pregnancy termination in a general practice on Curaçao].

  Nederlands tijdschrift voor geneeskunde 20080301

• [A case of rheumatoid arthritis complicated with methotrexate-induced pneumonitis and pneumocystis pneumonia].

  Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20080301

• Effect of anticancer drugs on production of transforming growth factor and expression of p53 AND Bcl-2 proteins by MCF-7 and T47D cell lines of human breast carcinoma.

  Experimental oncology 20080301

• High-dose methotrexate in adults with osteosarcoma: a population pharmacokinetics study and validation of a new limited sampling strategy.

  Anti-cancer drugs 20080301

• Beta-thalassaemia major: bone marrow versus peripheral blood stem cell transplantation.

  JPMA. The Journal of the Pakistan Medical Association 20080301

• Clinical findings following Ahmed Glaucoma Valve implantation in pediatric glaucoma.

  Clinical ophthalmology (Auckland, N.Z.) 20080301

• Self-aggregated nanoparticles from methoxy poly(ethylene glycol)-modified chitosan: synthesis; characterization; aggregation and methotrexate release in vitro.

  Colloids and surfaces. B, Biointerfaces 20080215

• Synthesis and biological evaluation of novel 2,4-diaminoquinazoline derivatives as SMN2 promoter activators for the potential treatment of spinal muscular atrophy.

  Journal of medicinal chemistry 20080214

• [Three cases of adult Still disease].

  Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20080210

• Improving outcomes for patients with hormone receptor-positive breast cancer: back to the drawing board.

  Journal of the National Cancer Institute 20080206

• Predictive value of tumor Ki-67 expression in two randomized trials of adjuvant chemoendocrine therapy for node-negative breast cancer.

  Journal of the National Cancer Institute 20080206

• Treatment of neurodegenerative CNS disease in Langerhans cell histiocytosis with a combination of intravenous immunoglobulin and chemotherapy.

  Pediatric blood & cancer 20080201

• Impaired clearance of methotrexate in organic anion transporter 3 (Slc22a8) knockout mice: a gender specific impact of reduced folates.

  Pharmaceutical research 20080201

• Intensive chemotherapy followed by consolidative myeloablative chemotherapy with autologous hematopoietic cell rescue (AuHCR) in young children with newly diagnosed supratentorial primitive neuroectodermal tumors (sPNETs): report of the Head Start I and II experience.

  Pediatric blood & cancer 20080201

• Effect of radiation dose on local control in breast cancer.

  Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20080201

• Initiating etanercept in a once weekly dose in children with juvenile idiopathic arthritis.

  Rheumatology international 20080201

• Intraarterial chemotherapy and osmotic blood-brain barrier disruption for patients with embryonal and germ cell tumors of the central nervous system.

  Cancer 20080201

• Frequency and spectrum of central nervous system involvement in 193 children with haemophagocytic lymphohistiocytosis.

  British journal of haematology 20080201

• Preclinical antitumor efficacy evaluation of dendrimer-based methotrexate conjugates.

  Anti-cancer drugs 20080201

• Gestational choriocarcinoma: morphological features in a liquid-based endometrial cytological sample.

  Diagnostic cytopathology 20080201

• Treatment of pregnant and non-pregnant rheumatic patients: a survey among Dutch rheumatologists.

  Journal of clinical pharmacy and therapeutics 20080201

• Chemotherapy-induced mucositis is associated with changes in proteolytic pathways.

  Experimental biology and medicine (Maywood, N.J.) 20080201

• Maculopathy in patients with primary CNS lymphoma treated with chemotherapy in conjunction with blood-brain barrier disruption.

  The British journal of ophthalmology 20080201

• Osteosarcoma: the addition of muramyl tripeptide to chemotherapy improves overall survival--a report from the Children's Oncology Group.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080201

• Clinical features and outcome of neuropsychiatric lupus in Chinese: analysis of 240 hospitalized patients.

  Lupus 20080201

• Steroid-resistant adult-onset Still's disease which showed a quick response to methotrexate.

  The Journal of dermatology 20080201

• [Population pharmacokinetics of high-dose methotrexate administered in 329 children with acute lymphoblastic leukemia].

  Zhongguo shi yan xue ye xue za zhi 20080201

• [Case of malignant lymphoma associated with rheumatoid arthritis].

  Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20080201

• [Adjuvant simultaneous mistletoe chemotherapy in breast cancer--influence on immunological parameters, quality of life and tolerability].

  Forschende Komplementarmedizin (2006) 20080201

• Methotrexate as single therapy in Crohn's disease: is its long-term efficacy limited?

  Gastroenterologie clinique et biologique 20080201

• [The liver and methotrexate].

  Gastroenterologie clinique et biologique 20080201

• Persistent neurocognitive problems after adjuvant chemotherapy for breast cancer.

  Clinical breast cancer 20080201

• Cytotoxic drug-induced, p53-mediated upregulation of caspase-8 in tumor cells.

  Oncogene 20080131

• [Impotence caused by Methotrexate treatment].

  Ugeskrift for laeger 20080128

• Long-lasting suppression of hippocampal cell proliferation and impaired cognitive performance by methotrexate in the rat.

  Behavioural brain research 20080125

• Lessons from the initial adjuvant cyclophosphamide, methotrexate, and fluorouracil studies in operable breast cancer.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080120

• Adjuvant chemotherapy with sequential or concurrent anthracycline and docetaxel: Breast International Group 02-98 randomized trial.

  Journal of the National Cancer Institute 20080116

• Transcriptional regulation of aldo-keto reductase 1C1 in HT29 human colon cancer cells resistant to methotrexate: role in the cell cycle and apoptosis.

  Biochemical pharmacology 20080115

• Profiling Protein Arginine Deiminase 4 (PAD4): a novel screen to identify PAD4 inhibitors.

  Bioorganic & medicinal chemistry 20080115

• Rituximab improves the treatment results of DHAP-VIM-DHAP and ASCT in relapsed/progressive aggressive CD20+ NHL: a prospective randomized HOVON trial.

  Blood 20080115

• Methotrexate, vinblastine, doxorubicin and cisplatin combination regimen as salvage chemotherapy for patients with advanced or metastatic transitional cell carcinoma after failure of gemcitabine and cisplatin chemotherapy.

  British journal of cancer 20080115

• Design, synthesis, and biological evaluation of classical and nonclassical 2-amino-4-oxo-5-substituted-6-methylpyrrolo[3,2-d]pyrimidines as dual thymidylate synthase and dihydrofolate reductase inhibitors.

  Journal of medicinal chemistry 20080110

• Long-term results of the AIEOP-ALL-95 Trial for Childhood Acute Lymphoblastic Leukemia: insight on the prognostic value of DNA index in the framework of Berlin-Frankfurt-Muenster based chemotherapy.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080110

• The role of the mitochondrial glycine cleavage complex in the metabolism and virulence of the protozoan parasite Leishmania major.

  The Journal of biological chemistry 20080104

• Effect of systemic adjuvant treatment on risk for contralateral breast cancer in the Women's Environment, Cancer and Radiation Epidemiology Study.

  Journal of the National Cancer Institute 20080102

• Intracerebral hematoma as a complication of intrathecal methotrexate administration.

  Pediatric blood & cancer 20080101

• Renal failure after high-dose methotrexate in a child homozygous for MTHFR C677T polymorphism.

  Pediatric blood & cancer 20080101

• Methylenetetrahydrofolate reductase (MTHFR) C677T and thymidylate synthase promoter (TSER) polymorphisms in Indonesian children with and without leukemia.

  Leukemia research 20080101

• Synthesis of N-(5,7-diamino-3-phenyl-quinoxalin-2-yl)-3,4,5-substituted anilines and N-[4[(5,7-diamino-3-phenylquinoxalin-2-yl)amino]benzoyl]-l-glutamic acid diethyl ester: evaluation of in vitro anti-cancer and anti-folate activities.

  European journal of medicinal chemistry 20080101

• An increase in cell number at completion of therapy may develop as an indicator of early relapse: quantification of circulating epithelial tumor cells (CETC) for monitoring of adjuvant therapy in breast cancer.

  Journal of cancer research and clinical oncology 20080101

• Serbian lymphoma study group (SLG): the prognosis of AIDS-related non-Hodgkin's lymphoma.

  Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20080101

• Anemia during adjuvant non-taxane chemotherapy for early breast cancer: Incidence and risk factors from two trials of the International Breast Cancer Study Group.

  Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20080101

• Adult onset Still's disease: a study of 14 cases.

  Clinical rheumatology 20080101

• EMA-CO chemotherapy for high-risk gestational trophoblastic neoplasia: a clinical analysis of 54 patients.

  International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20080101

• [Spontaneous tongue necrosis consecutive to rheumatoid hyperviscosity syndrome. A case report and literature review].

  Laryngo- rhino- otologie 20080101

• Mitoxantrone as induction treatment in aggressive relapsing remitting multiple sclerosis: treatment response factors in a 5 year follow-up observational study of 100 consecutive patients.

  Journal of neurology, neurosurgery, and psychiatry 20080101

• Leflunomide and methotrexate reduce levels of activated matrix metalloproteinases in complexes with alpha2 macroglobulin in serum of rheumatoid arthritis patients.

  Annals of the rheumatic diseases 20080101

• Review article: the evidence base for interventions used to maintain remission in Crohn's disease.

  Alimentary pharmacology & therapeutics 20080101

• Unmanipulated HLA 2-3 antigen-mismatched (haploidentical) bone marrow transplantation using only pharmacological GVHD prophylaxis.

  Experimental hematology 20080101

• Treatment for low-risk gestational trophoblastic disease: comparison of single-agent methotrexate, dactinomycin and combination regimens.

  Gynecologic oncology 20080101

• Clinical and radiological characteristics of methotrexate-induced acute encephalopathy in pediatric patients with cancer.

  Annals of oncology : official journal of the European Society for Medical Oncology 20080101

• Prescribing of sulfasalazine, azathioprine and methotrexate round pregnancy--a descriptive study.

  Pharmacoepidemiology and drug safety 20080101

• Central nervous system involvement in mantle cell lymphoma.

  Annals of oncology : official journal of the European Society for Medical Oncology 20080101

• Methotrexate vs. ciclosporin in psoriasis: effectiveness, quality of life and safety. A randomized controlled trial.

  The British journal of dermatology 20080101

• Expression level of beta protein 1 mRNA in Chinese breast cancer patients: a potential molecular marker for poor prognosis.

  Cancer science 20080101

• Genetic and epigenetic alterations of the reduced folate carrier in untreated diffuse large B-cell lymphoma.

  European journal of haematology 20080101

• A pilot study of pharmacokinetically guided dosing of oral methotrexate in the initial phase of psoriasis treatment.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20080101

• Pattern recognition based on color-coded quantum mechanical surfaces for molecular alignment.

  Journal of molecular modeling 20080101

• Daily practice effectiveness of a step-down treatment in comparison with a tight step-up for early rheumatoid arthritis.

  Rheumatology (Oxford, England) 20080101

• Methotrexate pneumonitis precipitated by switching from oral to parenteral administration.

  Rheumatology (Oxford, England) 20080101

• Hepatitis A-associated macrophage activation syndrome in children with systemic juvenile idiopathic arthritis: report of 2 cases.

  The Journal of rheumatology 20080101

• COBRA combination therapy in daily practice--getting back to the future.

  Rheumatology (Oxford, England) 20080101

• Synergistic effect of iontophoresis and soluble microneedles for transdermal delivery of methotrexate.

  The Journal of pharmacy and pharmacology 20080101

• Methotrexate-induced papular eruption following treatment of psoriasis.

  The Annals of pharmacotherapy 20080101

• Long-term outcome of adjuvant chemotherapy cyclophosphamide, mitoxantrone, and fluorouracil in women with breast cancer.

  Acta oncologica (Stockholm, Sweden) 20080101

• Folate pathway genetic polymorphisms are related to attention disorders in childhood leukemia survivors.

  The Journal of pediatrics 20080101

• Methotrexate loaded polyether-copolyester dendrimers for the treatment of gliomas: enhanced efficacy and intratumoral transport capability.

  Molecular pharmaceutics 20080101

• Efficacy and tolerability of high-dose methotrexate in central nervous system positive or relapsed lymphoproliferative disease following liver transplant in children.

  British journal of haematology 20080101

• Ondansetron-associated hypokalemia in a 2-year-old with pre-B-cell ALL.

  Journal of pediatric hematology/oncology 20080101

• Methotrexate and liver function: a study of 13 psoriasis cases treated with different cumulative dosages.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20080101

• HER2 over-expression and response to different chemotherapy regimens in breast cancer.

  Journal of Zhejiang University. Science. B 20080101

• Integration of modeling and simulation into hospital-based decision support systems guiding pediatric pharmacotherapy.

  BMC medical informatics and decision making 20080101

• [Protective effect of curcumin against methotrexate-induced small intestinal damage in rats].

  Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20080101

• Conjunctival involvement in chronic recurrent multifocal osteomyelitis.

  Cornea 20080101

• Primary cutaneous Cryptococcosis during therapy with methotrexate and adalimumab.

  Journal of drugs in dermatology : JDD 20080101

• Results of a phase III clinical trial: CHOP versus CMED in peripheral T-cell lymphoma unspecified.

  Medical oncology (Northwood, London, England) 20080101

• Wound healing in patients with cancer.

  Eplasty 20080101

• Concurrent use of methotrexate and acitretin revisited.

  The Journal of dermatological treatment 20080101

• Improving therapeutic options for patients with giant cell arteritis.

  Current opinion in rheumatology 20080101

• Clinical course of breast cancer patients with metastases limited to the liver treated with chemotherapy.

  Cancer journal (Sudbury, Mass.) 20080101

• Combination chemotherapy in feline lymphoma: treatment outcome, tolerability, and duration in 23 cats.

  Journal of veterinary internal medicine 20080101

• Otologic and leptomeningeal involvements as presenting features in seronegative Wegener granulomatosis.

  American journal of otolaryngology 20080101

• Sensitivity of mesenchymal stem cells and their progeny to medicines used for the treatment of hematoproliferative diseases.

  Acta haematologica 20080101

• [Long-term control of psoriasis is necessary].

  Actas dermo-sifiliograficas 20080101

• Eosinophilic pneumonia (EP) associated with rheumatoid arthritis in which drug-induced eosinophilic pneumonia could be ruled out.

  Internal medicine (Tokyo, Japan) 20080101

• Methotrexate and cyclosporine treatments modify the activities of dipeptidyl peptidase IV and prolyl oligopeptidase in murine macrophages.

  Clinical & developmental immunology 20080101

• Varicella-zoster virus hepatitis in polymyositis.

  Modern rheumatology 20080101

• Reversible infliximab-related lymphoproliferative disorder associated with Epstein-Barr virus in a patient with rheumatoid arthritis.

  Modern rheumatology 20080101

• Pharmacogenomics in rheumatoid arthritis.

  Methods in molecular biology (Clifton, N.J.) 20080101

• [Necrotizing systemic sarcoidosis with pulmonary and central nervous system involvement].

  Anales de medicina interna (Madrid, Spain : 1984) 20080101

• [Pneumonitis associated to methotrexate].

  Anales de medicina interna (Madrid, Spain : 1984) 20080101

• Intravitreal methotrexate resistance in a patient with primary intraocular lymphoma.

  Ocular immunology and inflammation 20080101

• Systemic onset juvenile chronic arthritis (JCA) in a Nigerian boy--a case report.

  Nigerian journal of medicine : journal of the National Association of Resident Doctors of Nigeria 20080101

• Chemotherapy and cerebrovascular disease.

  Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20080101

• Treatment of Sézary syndrome with bexarotene after IFNalpha and methotrexate failure.

  Dermatologic clinics 20080101

• Bexarotene salvage therapy in a patient with refractory erythrodermic mycosis fungoides after failure on interferon/PUVA and methotrexate.

  Dermatologic clinics 20080101

• Recurrent neovascularization of the disc in sympathetic ophthalmia.

  Indian journal of ophthalmology 20080101

• Tumor necrosis factor alpha drugs in rheumatoid arthritis: systematic review and metaanalysis of efficacy and safety.

  BMC musculoskeletal disorders 20080101

• Systemic methotrexate treatment in childhood psoriasis: further experience in 24 children from India.

  Pediatric dermatology 20080101

• Chemotherapy-induced acral erythema in a pediatric patient with acute monoblastic leukemia.

  Pediatric hematology and oncology 20080101

• RM-11, an isoxazole derivative, accelerates restoration of the immune function in mice treated with cyclophosphamide.

  Pharmacological reports : PR 20080101

• Quantitative correlation between promoter methylation and messenger RNA levels of the reduced folate carrier.

  BMC cancer 20080101

• Efficacy of low-dose tacrolimus added to methotrexate in patients with rheumatoid arthritis in Japan: a retrospective study.

  Modern rheumatology 20080101

• Adjuvant cyclophosphamide, methotrexate, and fluorouracil in premonopausal patients with node-positive breast cancer: indirect comparison of dose and schedule in DBCG trials 77, 82, and 89.

  Acta oncologica (Stockholm, Sweden) 20080101

• DBCG trial 89B comparing adjuvant CMF and ovarian ablation: similar outcome for eligible but non-enrolled and randomized breast cancer patients.

  Acta oncologica (Stockholm, Sweden) 20080101

• The value of TOP2A gene copy number variation as a biomarker in breast cancer: Update of DBCG trial 89D.

  Acta oncologica (Stockholm, Sweden) 20080101

• Bisphosphonate treatment in primary breast cancer: results from a randomised comparison of oral pamidronate versus no pamidronate in patients with primary breast cancer.

  Acta oncologica (Stockholm, Sweden) 20080101

• [Adjuvant chemotherapy as a component of complex treatment for skin melanoma].

  Voprosy onkologii 20080101

• Liposomes formed in sintered glass pores.

  Acta poloniae pharmaceutica 20080101

• Use of methotrexate to treat isolated Graves ophthalmopathy developing years after thyroidectomy and iodine 131 treatment of papillary thyroid cancer.

  Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20080101

• You're too old for that.

  Survey of ophthalmology 20080101

• Long-term follow-up of polymyalgia rheumatica patients treated with methotrexate and steroids.

  Clinical and experimental rheumatology 20080101

• Tumor necrosis factor alpha inhibitors, methotrexate or both? An inquiry into the formal evidence for when they are to be used in rheumatoid arthritis.

  Clinical and experimental rheumatology 20080101

• Co-occurrence of subchondral insufficiency fracture of the femoral head and contralateral femoral neck fracture in a rheumatic patient receiving steroid treatment.

  Modern rheumatology 20080101

• [Comparison of efficacy and tolerability of triple combination therapy (methotrexate + sulfasalazine + hydroxychloroquine) with methotrexate monotherapy in patients with rheumatoid arthritis].

  Terapevticheskii arkhiv 20080101

• [Cutaneous Bipolaris spicifera infection in a patient on systemic corticosteroids].

  Annales de dermatologie et de venereologie 20080101

• Modulation of gene expression in drug resistant Leishmania is associated with gene amplification, gene deletion and chromosome aneuploidy.

  Genome biology 20080101

• Autologous stem cell transplantation in first-line treatment of high-risk aggressive non-Hodgkin's lymphoma.

  Neoplasma 20080101

• Treatment of primary intraocular lymphoma with intravitreal methotrexate.

  Japanese journal of ophthalmology 20080101

• Dorsal midbrain syndrome induced by midbrain neurosarcoidosis.

  Japanese journal of ophthalmology 20080101

• Role of methotrexate in the treatment of bullous pemphigoid in the elderly.

  Drugs & aging 20080101

• Cytotoxic and genotoxic effects of methotrexate in germ cells of male Swiss mice.

  Mutation research 20080101

• Role of caveolin 1, E-cadherin, Enolase 2 and PKCalpha on resistance to methotrexate in human HT29 colon cancer cells.

  BMC medical genomics 20080101

• Rapid onset proptosis and vision loss as the initial presentation of Burkitt lymphoma.

  Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye 20080101

• [Adult acute lymphoblastic leukemia with central nervous system involvement: an overview].

  Bulletin du cancer 20080101

• [Efficacy of therapy of different variants of anaplastic large T-cell lymphomas].

  Terapevticheskii arkhiv 20080101

• Significant improvement of axillary artery stenosis in a 67 year-old woman with giant cell arteritis.

  Clinical and experimental rheumatology 20080101

• Renal conservation of folates role of folate transport proteins.

  Vitamins and hormones 20080101

• Discontinuation of methotrexate therapy in older patients with newly diagnosed rheumatoid arthritis: analysis of administrative health databases in Québec, Canada.

  Drugs & aging 20080101

• Correlation between magnetic resonance imaging and histopathological tumor response after neoadjuvant chemotherapy in breast cancer.

  Tumori 20080101

• Modulatory effects of inflammation and therapy on GDF-5 expression in rheumatoid arthritis synovium.

  Scandinavian journal of rheumatology 20080101

• The treatment of giant cell arteritis.

  Reviews in neurological diseases 20080101

• [Fish oil supplementation in rheumatoid arthritis].

  Reumatismo 20080101

• [Complex etiology of acute renal failure in a newborn].

  Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20080101

• T-614, a novel immunomodulator, attenuates joint inflammation and articular damage in collagen-induced arthritis.

  Arthritis research & therapy 20080101

• Self-assembly of antibodies by chemical induction.

  Angewandte Chemie (International ed. in English) 20080101

• Toxic encephalopathy and delayed MTX clearance after high-dose methotrexate therapy in a child homozygous for the MTHFR C677T polymorphism.

  Anticancer research 20080101

• [Pharmacogenomics of methrotexate: a strategy for a customized therapeutic scheme for patients with rheumatoid arthritis].

  Gaceta medica de Mexico 20080101

• Role of grape seed extract on methotrexate induced oxidative stress in rat liver.

  The American journal of Chinese medicine 20080101

• Treatment of acute lymphoblastic leukemia in children and adolescents: peaks and pitfalls.

  Hematology. American Society of Hematology. Education Program 20080101

• FDG-PET and MIBI-Tc SPECT as follow-up tools in a patient with cardiac sarcoidosis requiring a pacemaker.

  Cardiovascular journal of Africa 20080101

• [Optimal role of docetaxel in adjuvant chemotherapy for early stage HER2-negative breast cancer].

  La Clinica terapeutica 20080101

• [Digestive disease in the immunocompromised patient with acute lymphoblastic leukemia. Experience of the IVth Pediatric Clinic--Oncology Department of the Iaşi Sfânta Maria Children's Hospital].

  Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20080101

• [Analysis of therapy results and prognostic factors in children with acute lymphoblastic leukaemia in Warmia and Mazury region: 17-years experience].

  Medycyna wieku rozwojowego 20080101

• Outcome after relapse among children with standard-risk acute lymphoblastic leukemia: Children's Oncology Group study CCG-1952.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20071220

• Primary central nervous system lymphomas: salvage treatment after failure to high-dose methotrexate.

  Cancer letters 20071218

• Reduced folate carrier-1 80G>A polymorphism affects methotrexate treatment outcome in rheumatoid arthritis.

  The pharmacogenomics journal 20071201

• MTHFR polymorphisms' influence on outcome and toxicity in acute lymphoblastic leukemia patients.

  Leukemia research 20071201

• Pericarditis: a rare complication of methotrexate therapy.

  Clinical rheumatology 20071201

• Gestational choriocarcinoma arising from a cornual ectopic pregnancy: a case report and review of the literature.

  Archives of gynecology and obstetrics 20071201

• Two cases of isolated symptomatic myocarditis induced by all-trans retinoic acid (ATRA).

  Annals of hematology 20071201

• Disseminated strongyloidiasis and cytomegalovirus infection in a patient with anaplastic large cell lymphoma.

  Annals of hematology 20071201

• Ad-PUMA sensitizes drug-resistant choriocarcinoma cells to chemotherapeutic agents.

  Gynecologic oncology 20071201

• Anti-tumor necrosis factor-alpha therapy in the ordinary clinical setting: Three-year effectiveness in patients with rheumatoid arthritis.

  Joint, bone, spine : revue du rhumatisme 20071201

• Multichannel liquid chromatography-tandem mass spectrometry cocktail method for comprehensive substrate characterization of multidrug resistance-associated protein 4 transporter.

  Pharmaceutical research 20071201

• Cytarabine induced noncardiogenic pulmonary edema in a case of acute lymphoblastic leukemia.

  International journal of laboratory hematology 20071201

• Comparative study of the pharmacokinetics of MTX in juvenile idiopathic arthritis patients receiving long-term MTX monotherapy or MTX plus chloroquine.

  Journal of clinical pharmacy and therapeutics 20071201

• High-performance liquid chromatography separation of aminopterin-polyglutamates within red blood cells of children treated for acute lymphoblastic leukemia.

  Translational research : the journal of laboratory and clinical medicine 20071201

• Re: Maculopathy as a complication of blood-brain barrier disruption in patients with central nervous system lymphoma.

  American journal of ophthalmology 20071201

• Methotrexate following unsuccessful thiopurine therapy in pediatric Crohn's disease.

  The American journal of gastroenterology 20071201

• Achievement of target cyclosporine concentrations as a predictor of severe acute graft versus host disease in children undergoing hematopoietic stem cell transplantation and receiving cyclosporine and methotrexate prophylaxis.

  Therapeutic drug monitoring 20071201

• Successful high-dose methotrexate chemotherapy in a patient with acute lymphocytic leukemia who developed acute renal failure during the initial treatment.

  Pediatrics international : official journal of the Japan Pediatric Society 20071201

• Treatment of early rheumatoid arthritis: a randomized magnetic resonance imaging study comparing the effects of methotrexate alone, methotrexate in combination with infliximab, and methotrexate in combination with intravenous pulse methylprednisolone.

  Arthritis and rheumatism 20071201

• Disease remission and sustained halting of radiographic progression with combination etanercept and methotrexate in patients with rheumatoid arthritis.

  Arthritis and rheumatism 20071201

• [Secondary osteoporosis. Bisphosphonates as a possible strategy for the prevention of bone destruction in rheumatoid arthritis].

  Clinical calcium 20071201

• [Two cases of stage IV gastric cancer who underwent total gastrectomy and achieved long-term survival by sequential chemotherapy].

  Gan to kagaku ryoho. Cancer & chemotherapy 20071201

• Pharmacogenomics of microRNA: a miRSNP towards individualized therapy.

  Pharmacogenomics 20071201

• In vitro transport of gimatecan (7-t-butoxyiminomethylcamptothecin) by breast cancer resistance protein, P-glycoprotein, and multidrug resistance protein 2.

  Molecular cancer therapeutics 20071201

• Early acute myeloblastic leukemia treatment for childhood myelodysplastic syndrome with t(3;5) (NPM/MLF1).

  Journal of pediatric hematology/oncology 20071201

• Clinical and pathologic manifestations of necrobiosis lipoidica-like skin involvement in sarcoidosis.

  Joint, bone, spine : revue du rhumatisme 20071201

• Combined systemic therapy and radiotherapy for bladder cancer.

  Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] 20071201

• Bilateral occlusive retinal vasculitis in Kikuchi-Fujimoto disease.

  Clinical & experimental ophthalmology 20071201

• Correlations between symptoms as assessed in traditional chinese medicine (TCM) and ACR20 efficacy response: a comparison study in 396 patients with rheumatoid arthritis treated with TCM or Western medicine.

  Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20071201

• Cutaneous mucormycosis complicating methotrexate, prednisone, and infliximab therapy.

  Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20071201

• [Pancytopenia induced by two low-dose injections of methotrexate in a patient treated for ulcerative colitis].

  Gastroenterologie clinique et biologique 20071201

• Methylenetetrahydrofolate reductase C677T genotypes and clinical outcome following hematopoietic cell transplant.

  Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20071201

• [Comparative study on characteristics of Chinese and Western medicine for treatment of rheumatoid arthritis regarding cartilage erosion related blood biochemical and immunological factors].

  Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20071201

• Isolated periaortitis: clinical and imaging characteristics.

  Vascular health and risk management 20071201

• Efficacy of primary systemic chemotherapy regimen containing anthracyclines with/without taxanes in comparison to CMF in women with early breast cancer.

  Journal of chemotherapy (Florence, Italy) 20071201

• Effect of methotrexate (MTX) administration on spermatogenesis: an experimental on animal model.

  Nepal Medical College journal : NMCJ 20071201

• Methotrexate decreases PP2A methylation and increases tau phosphorylation in neuron.

  Biochemical and biophysical research communications 20071123

• Erlotinib (Tarceva, OSI-774) antagonizes ATP-binding cassette subfamily B member 1 and ATP-binding cassette subfamily G member 2-mediated drug resistance.

  Cancer research 20071115

• [Giant cell arteritis].

  Praxis 20071114

• Dermal and transdermal delivery of an anti-psoriatic agent via ethanolic liposomes.

  Journal of controlled release : official journal of the Controlled Release Society 20071106

• Effective treatment of kaposiform hemangioendotheliomas associated with Kasabach-Merritt phenomenon using four-drug regimen.

  Pediatric blood & cancer 20071101

• Cisplatin-induced hypomagnesemia and cardiac dysrhythmia.

  Pediatric blood & cancer 20071101

• Multiple eruptive dermatofibromas in a patient with dermatomyositis taking prednisolone and methotrexate.

  Journal of the American Academy of Dermatology 20071101

• Simultaneous occurrence of Wilms tumor and Burkitt lymphoma in two brothers.

  Pediatric blood & cancer 20071101

• Spontaneous multiple insufficiency fractures after pelvic abscess and sepsis in a rheumatoid arthritis patient treated with high-load corticosteroid therapy: a case report.

  Clinical rheumatology 20071101

• Long-term outcome of juvenile idiopathic arthritis following a placebo-controlled trial: sustained benefits of early sulfasalazine treatment.

  Annals of the rheumatic diseases 20071101

• Best practice in primary care pathology: review 10.

  Journal of clinical pathology 20071101

• Membrane cholesterol selectively modulates the activity of the human ABCG2 multidrug transporter.

  Biochimica et biophysica acta 20071101

• Serine hydroxymethyltransferase isoforms are differentially inhibited by leucovorin: characterization and comparison of recombinant zebrafish serine hydroxymethyltransferases.

  Drug metabolism and disposition: the biological fate of chemicals 20071101

• Risk factors for acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation: retrospective analysis of 73 patients who received cyclosporin A.

  Bone marrow transplantation 20071101

• [Wegener's granulomatosis in ENT: clinical presentation, diagnosis and therapy].

  Laryngo- rhino- otologie 20071101

• Disseminated cryptococcal infection in a patient with severe psoriasis treated with efalizumab, methotrexate and ciclosporin.

  The British journal of dermatology 20071101

• Intramuscular methotrexate-induced aseptic meningitis.

  The Annals of pharmacotherapy 20071101

• Temozolomide and methotrexate for primary central nervous system lymphoma in the elderly.

  Journal of neuro-oncology 20071101

• Rodent intestinal folate transporters (SLC46A1): secondary structure, functional properties, and response to dietary folate restriction.

  American journal of physiology. Cell physiology 20071101

• 18F-FDG PET/CT in primary central nervous system lymphoma in HIV-negative patients.

  Nuclear medicine communications 20071101

• Gemcitabine and paclitaxel chemotherapy as a second-line treatment for advanced or metastatic urothelial carcinoma.

  International journal of urology : official journal of the Japanese Urological Association 20071101

• Cloning and functional characterization of the proton-coupled electrogenic folate transporter and analysis of its expression in retinal cell types.

  Investigative ophthalmology & visual science 20071101

• Neuropsychological outcomes from a randomized trial of triple intrathecal chemotherapy compared with 18 Gy cranial radiation as CNS treatment in acute lymphoblastic leukemia: findings from Dana-Farber Cancer Institute ALL Consortium Protocol 95-01.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20071101

• Clinical inquiries. Are DMARDs effective for rheumatologic diseases besides rheumatoid arthritis?

  The Journal of family practice 20071101

• [Polymyositis and interstitial lung disease with a favorable response to corticosteroids and methotrexate].

  Archivos de bronconeumologia 20071101

• Bilateral periocular psoriasis: an initial manifestation of acute generalized pustular psoriasis with coexistent Sjögren's syndrome.

  Clinical & experimental ophthalmology 20071101

• [Pharmacogenomics of acute lymphoblastic leukemia].

  Medecine sciences : M/S 20071101

• Effects of folate and folylpolyglutamyl synthase modulation on chemosensitivity of breast cancer cells.

  Molecular cancer therapeutics 20071101

• Silica-based mesoporous materials as drug delivery system for methotrexate release.

  Drug delivery 20071101

• [Results of chemotherapy using new anti-cancer drugs since S-1 for advanced or recurrent gastric cancer in our institute].

  Gan to kagaku ryoho. Cancer & chemotherapy 20071101

• [Fever and nonspecific pulmonary lesions--a rare differential diagnosis].

  Deutsche medizinische Wochenschrift (1946) 20071101

• 677C>T and 1298A>C MTHFR polymorphisms affect methotrexate treatment outcome in rheumatoid arthritis.

  Pharmacogenomics 20071101

• Five clinical conundrums in the management of giant cell arteritis.

  Rheumatic diseases clinics of North America 20071101

• Glucarpidase (carboxypeptidase g2) intervention in adult and elderly cancer patients with renal dysfunction and delayed methotrexate elimination after high-dose methotrexate therapy.

  The oncologist 20071101

• [Results of a study on fatigue in breast cancer patients receiving adjuvant chemotherapy: the first four days after treatment are the worst].

  Pflege Zeitschrift 20071101

• Effect of methotrexate on alveolar bone loss in experimental periodontitis in Wistar rats.

  Acta odontologica Scandinavica 20071101

• Giant cell arteritis.

  Current opinion in ophthalmology 20071101

• [Adverse effects of conventional DMARDs and biologic DMARDs].

  Nihon rinsho. Japanese journal of clinical medicine 20071028

• [Drug-induced leukoencephalopathy].

  Nihon rinsho. Japanese journal of clinical medicine 20071028

• Increasing methotrexate resistance by combination of active-site mutations in human dihydrofolate reductase.

  Journal of molecular biology 20071026

• Amplification of CCND1 and PAK1 as predictors of recurrence and tamoxifen resistance in postmenopausal breast cancer.

  Oncogene 20071025

• Combined immunochemotherapy with reduced whole-brain radiotherapy for newly diagnosed primary CNS lymphoma.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20071020

• Intensive chemotherapy regimen (LMB86) for St Jude stage IV AIDS-related Burkitt lymphoma/leukemia: a prospective study.

  Blood 20071015

• The importance of the disease process and disease-modifying antirheumatic drug treatment in the development of septic arthritis in patients with rheumatoid arthritis.

  Arthritis and rheumatism 20071015

• Isolated sixth nerve palsy following low dose oral methotrexate.

  Dermatology online journal 20071013

• Limited efficacy of conventional DMARDs after initial methotrexate failure in patients with recent onset rheumatoid arthritis treated according to the disease activity score.

  Annals of the rheumatic diseases 20071001

• Massive myelinolytic leukoencephalopathy in a patient medicated with low-dose oral methotrexate for rheumatoid arthritis: an autopsy report.

  Acta neuropathologica 20071001

• Response-driven combination therapy with conventional disease-modifying antirheumatic drugs can achieve high response rates in early rheumatoid arthritis with minimal glucocorticoid and nonsteroidal anti-inflammatory drug use.

  Seminars in arthritis and rheumatism 20071001

• Neoadjuvant chemotherapy in locally advanced primary breast cancers: the Nottingham experience.

  European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 20071001

• What is the best salvage therapy for treatment of isolated CNS relapse in elderly patients with imatinib-responsive Ph(+) ALL?

  Leukemia research 20071001

• Interferon gamma assay for detecting latent tuberculosis infection in rheumatoid arthritis patients during infliximab administration.

  Rheumatology international 20071001

• Transgenic rescue of methotrexate-induced teratogenicity in Drosophila melanogaster.

  Toxicological sciences : an official journal of the Society of Toxicology 20071001

• Prospective phase II trial to evaluate the complications and kinetics of chimerism induction following allogeneic hematopoietic stem cell transplantation with fludarabine and busulfan.

  American journal of hematology 20071001

• The pharmacogenetics of methotrexate.

  Rheumatology (Oxford, England) 20071001

• Pharmacokinetics of intravenous methotrexate in mutant Nagase analbuminemic rats.

  Biopharmaceutics & drug disposition 20071001

• Regression of the tumor after withdrawal of cyclosporine in relapsed extranodal natural killer/T cell lymphoma following allogeneic hematopoietic stem cell transplantation.

  American journal of hematology 20071001

• Medroxyprogesterone acetate induces c6 glioma chemosensitization via antidepressant-like lysosomal phospholipidosis/myelinosis in vitro.

  The International journal of neuroscience 20071001

• Infliximab but not methotrexate induces extra-high levels of VLDL-triglyceride in patients with rheumatoid arthritis.

  The Journal of rheumatology 20071001

• [Neoadjuvant and adjuvant chemotherapy in patients with advanced penile cancer].

  Der Urologe. Ausg. A 20071001

• Reduced-intensity conditioning for allogeneic haematopoietic stem cell transplantation in relapsed and refractory Hodgkin lymphoma: impact of alemtuzumab and donor lymphocyte infusions on long-term outcomes.

  British journal of haematology 20071001

• Methotrexate-induced mucositis in acute leukemia patients is not associated with the MTHFR 677T allele in Mexico.

  Hematology (Amsterdam, Netherlands) 20071001

• An improved application for the enzyme multipled immunoassay technique for caffeine, amikacin, and methotrexate assays on the Dade-Behring Dimension RxL Max clinical chemistry system.

  Therapeutic drug monitoring 20071001

• [Postoperative radiotherapy of the chest wall in patients with male breast cancer].

  Zentralblatt fur Chirurgie 20071001

• [Systemic therapy of male breast cancer].

  Zentralblatt fur Chirurgie 20071001

• pH and salivary sodium bicarbonate during the administration protocol for methotrexate in children with leukemia.

  Medicina oral, patologia oral y cirugia bucal 20071001

• Patterns of care study of breast-conserving therapy in Japan: comparison of the treatment process between 1995 1997 and 1999 2001 surveys.

  Japanese journal of clinical oncology 20071001

• Controversies of adjuvant endocrine treatment for breast cancer and recommendations of the 2007 St Gallen conference.

  The Lancet. Oncology 20071001

• Preliminary evidence shows that folic acid fortification of the food supply is associated with higher methotrexate dosing in patients with rheumatoid arthritis.

  Journal of the American College of Nutrition 20071001

• Retrospective study on elimination delay of methotrexate in high-dose therapy of childhood acute lymphoblastic leukemia in China.

  Journal of pediatric hematology/oncology 20071001

• [Clinical research advancement on male breast cancer].

  Ai zheng = Aizheng = Chinese journal of cancer 20071001

• Treatment, management, and monitoring of established rheumatoid arthritis.

  The Journal of family practice 20071001

• Methylenetetrahydrofolate reductase and reduced folate carrier-1 genotypes and methotrexate serum concentrations in patients with rheumatoid arthritis.

  The Journal of toxicological sciences 20071001

• Exploring protection from methotrexate-induced teratogenicity in flies.

  Toxicological sciences : an official journal of the Society of Toxicology 20071001

• [Strategy for chemical biology using affinity magnetic nanobeads].

  Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 20071001

• [Management of severe psoriasis: about 50 cases].

  La Tunisie medicale 20071001

• The evolving role of chemotherapy in advanced urothelial cancer.

  Current opinion in supportive and palliative care 20071001

• [New ways in the management of rheumatoid arthritis in Hungary].

  Lege artis medicinae : uj magyar orvosi hirmondo 20071001

• Nonmyeloablative stem cell transplantation in follicular B-cell lymphoma.

  Current hematologic malignancy reports 20071001

• Identification and characterization of genetic variation in the folylpolyglutamate synthase gene.

  Cancer research 20070915

• [Medical treatment of early breast cancer: chemotherapy].

  Ugeskrift for laeger 20070910

• Crystal structure of the anthrax drug target, Bacillus anthracis dihydrofolate reductase.

  Journal of medicinal chemistry 20070906

• [Therapeutic strategies against psoriasis. Skin to hide -- and how do you free your patients from it].

  MMW Fortschritte der Medizin 20070906

• A limited sampling strategy to estimate individual pharmacokinetic parameters of methotrexate in children with acute lymphoblastic leukemia.

  Cancer chemotherapy and pharmacology 20070901

• Transcription regulatory polymorphism -43T>C in the 5'-flanking region of SLC19A1 gene could affect rheumatoid arthritis patient response to methotrexate therapy.

  Rheumatology international 20070901

• [Pancytopenia related to low-dose methotrexate: study of five cases and review of the literature].

  La Revue de medecine interne 20070901

• Motor and perceptual timing deficits among survivors of childhood leukemia.

  Journal of pediatric psychology 20070901

• Granular acute lymphoblastic leukemia: a case report and literature review.

  American journal of hematology 20070901

• Species difference in the inhibitory effect of nonsteroidal anti-inflammatory drugs on the uptake of methotrexate by human kidney slices.

  The Journal of pharmacology and experimental therapeutics 20070901

• Protection of mice from methotrexate toxicity by ex vivo transduction using lentivirus vectors expressing drug-resistant dihydrofolate reductase.

  The Journal of pharmacology and experimental therapeutics 20070901

• Induction of acute lymphocytic leukemia differentiation by maintenance therapy.

  Leukemia 20070901

• Phase II study of chemotherapy and stem cell transplantation for adult acute lymphoblastic leukemia or lymphoblastic lymphoma: Japan Clinical Oncology Group Study 9004.

  Cancer science 20070901

• [Behçet's disease in treatment with cyclosporine and seizures: diagnostic dilemma].

  Revista clinica espanola 20070901

• Peripheral blood expression of nuclear factor-kappab-regulated genes is associated with rheumatoid arthritis disease activity and responds differentially to anti-tumor necrosis factor-alpha versus methotrexate.

  The Journal of rheumatology 20070901

• Immunotherapy of familial hemophagocytic lymphohistiocytosis with antithymocyte globulins: a single-center retrospective report of 38 patients.

  Pediatrics 20070901

• Clinical characteristics and treatment results of pediatric B-cell non-Hodgkin lymphoma patients in a single center.

  Pediatric hematology and oncology 20070901

• Re: Neurologic complications associated with intrathecal liposomal cytarabine given prophylactically in combination with high-dose methotrexate and cytarabine to patients with acute lymphocytic leukemia.

  Blood 20070901

• Synthesis and biological activity of stable branched neurotensin peptides for tumor targeting.

  Molecular cancer therapeutics 20070901

• Variation in the initial treatment of knee monoarthritis in juvenile idiopathic arthritis: a survey of pediatric rheumatologists in the United States and Canada.

  The Journal of rheumatology 20070901

• Prognosis of radiation-induced bone sarcoma is similar to primary osteosarcoma.

  Clinical orthopaedics and related research 20070901

• [An unusual case of pneumocystis pneumonia--case report and review].

  Laeknabladid 20070901

• [Do DMARDs contibute to impaired healing after surgery? Should they be discontinued before surgery?].

  Deutsche medizinische Wochenschrift (1946) 20070901

• Tranilast suppresses the disease development of the adjuvant- and streptococcal cell wall-induced arthritis in rats.

  Journal of pharmacological sciences 20070901

• [Lactoferrin reduces physiological dysfunctions of goldfish induced by chemotherapeutic agents].

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20070901

• Substitution of methotrexate for cyclophosphamide in Wegener granulomatosis: a 12-year single-practice experience.

  Medicine 20070901

• Dermal delivery of selected hydrophilic drugs from elastic liposomes: effect of phospholipid formulation and surfactants.

  The Journal of pharmacy and pharmacology 20070901

• Role of intestinal efflux transporters in the intestinal absorption of methotrexate in rats.

  The Journal of pharmacy and pharmacology 20070901

• Marked elevation in homocysteine and homocysteine sulfinic acid in the cerebrospinal fluid of lymphoma patients receiving intensive treatment with methotrexate.

  International journal of clinical pharmacology and therapeutics 20070901

• Management of high-risk hydatidiform mole and persistent gestational trophoblastic neoplasia: the Korean experience.

  The Journal of reproductive medicine 20070901

• [Clinical observation on effect of total glucosides of paeony combined with methotrexate on rheumatoid arthritis].

  Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20070901

• Similar outcome after unrelated allogeneic peripheral blood stem cell transplantation compared with bone marrow in children and adolescents.

  Transplantation 20070827

• Antimetabolite therapy for lesser-risk B-lineage acute lymphoblastic leukemia of childhood: a report from Children's Oncology Group Study P9201.

  Blood 20070815

• A miR-24 microRNA binding-site polymorphism in dihydrofolate reductase gene leads to methotrexate resistance.

  Proceedings of the National Academy of Sciences of the United States of America 20070814

• [Drug-induced leukoencephalopathy].

  Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20070810

• GAMEC--a new intensive protocol for untreated poor prognosis and relapsed or refractory germ cell tumours.

  British journal of cancer 20070806

• Successful treatment with voriconazole of Aspergillus brain abscess in a boy with medulloblastoma.

  Pediatric blood & cancer 20070801

• Comparison of treatment outcomes of childhood Hodgkin lymphoma in two US centers and a center in Recife, Brazil.

  Pediatric blood & cancer 20070801

• Acute renal failure in a 17-year-old female with ALL receiving escalating intravenous methotrexate without leukovorin.

  Pediatric blood & cancer 20070801

• Repetitive cycles of high-dose cytarabine are effective for childhood acute myeloid leukemia: long-term outcome of the children with AML treated on two consecutive trials of Tokyo Children's Cancer Study Group.

  Pediatric blood & cancer 20070801

• Inflammatory myositis complicating hypocomplementemic urticarial vasculitis despite on-going immunosuppression.

  Clinical rheumatology 20070801

• The contribution of Gianni Bonadonna to the history of chemotherapy.

  Cancer chemotherapy and pharmacology 20070801

• Systemic onset juvenile rheumatoid arthritis presenting with absence of B lymphocytes.

  Rheumatology international 20070801

• Step-up combination versus switching of non-biological disease-modifying antirheumatic drugs in rheumatoid arthritis: results from a retrospective observational study.

  Annals of the rheumatic diseases 20070801

• Neoadjuvant chemotherapy in advanced penile carcinoma.

  European urology 20070801

• Editorial comment on: Neoadjuvant chemotherapy in advanced penile carcinoma.

  European urology 20070801

• Central nervous system blastic crisis in chronic myeloid leukemia on imatinib mesylate therapy: a case report.

  Journal of neuro-oncology 20070801

• Folate deficiency in normal human fibroblasts leads to altered expression of genes primarily linked to cell signaling, the cytoskeleton and extracellular matrix.

  The Journal of nutritional biochemistry 20070801

• Genetic polymorphisms of folate metabolic enzymes and toxicities of high dose methotrexate in children with acute lymphoblastic leukemia.

  Annals of hematology 20070801

• Polymorphisms in folate, pyrimidine, and purine metabolism are associated with efficacy and toxicity of methotrexate in psoriasis.

  The Journal of investigative dermatology 20070801

• Eight versus 16-week re-evaluation period in rheumatoid arthritis patients treated with leflunomide or methotrexate accompanied by moderate dose prednisone.

  Rheumatology international 20070801

• Cloning and functional characterization of a folate transporter from the nematode Caenorhabditis elegans.

  American journal of physiology. Cell physiology 20070801

• Functional characterization of human proton-coupled folate transporter/heme carrier protein 1 heterologously expressed in mammalian cells as a folate transporter.

  The Journal of pharmacology and experimental therapeutics 20070801

• Mutational analysis of a highly conserved proline residue in MRP1, MRP2, and MRP3 reveals a partially conserved function.

  Drug metabolism and disposition: the biological fate of chemicals 20070801

• Tattooing breast cancers treated with neoadjuvant chemotherapy.

  Annals of surgical oncology 20070801

• Serum EGFR and serum HER-2/neu are useful predictive and prognostic markers in metastatic breast cancer patients treated with metronomic chemotherapy.

  Cancer 20070801

• Local recurrence and local control of non-metastatic osteosarcoma of the extremities: a 27-year experience in a single institution.

  Journal of surgical oncology 20070801

• Influence of thymidylate synthase and methylenetetrahydrofolate reductase gene polymorphisms on the disease-free survival of breast cancer patients receiving adjuvant 5-fluorouracil/methotrexate-based therapy.

  Anti-cancer drugs 20070801

• 2756GG genotype of methionine synthase reductase gene is more prevalent in rheumatoid arthritis patients treated with methotrexate and is associated with methotrexate-induced nodulosis.

  The Journal of rheumatology 20070801

• Treatment of parthenium dermatitis with methotrexate.

  Contact dermatitis 20070801

• Synthesis, cleavage profile, and antitumor efficacy of an albumin-binding prodrug of methotrexate that is cleaved by plasmin and cathepsin B.

  Archiv der Pharmazie 20070801

• Methods to enhance the safety of methotrexate prescribing.

  Journal of clinical pharmacy and therapeutics 20070801

• Combination therapy for rheumatoid arthritis: methotrexate and sulfasalazine together or with other DMARDs.

  Nature clinical practice. Rheumatology 20070801

• Therapeutic drug monitoring of methotrexate on the pediatric oncology ward: can blood sampling from central venous accesses substitute for capillary finger punctures?

  Therapeutic drug monitoring 20070801

• Treatment of metastatic gestational trophoblastic neoplasia.

  The Lancet. Oncology 20070801

• [Squamous cell carcinoma of the bladder treated with a new combined chemotherapy regimen, intraarterial nedaplatin and pirarubicin plus intravenous methotrexate and vincristine--second case report in Japan].

  Gan to kagaku ryoho. Cancer & chemotherapy 20070801

• Successful carboxypeptidase G2 rescue of a high-risk elderly Hodgkin lymphoma patient with methotrexate intoxication and renal failure.

  Leukemia & lymphoma 20070801

• [Methotrexate-induced pneumonitis in a woman with Crohn's disease].

  Deutsche medizinische Wochenschrift (1946) 20070801

• Check Program.

  Australian family physician 20070801

• A controlled study of double filtration plasmapheresis in the treatment of active rheumatoid arthritis.

  Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20070801

• Inhibition of Stenotrophomonas maltophilia dihydrofolate reductase by methotrexate: a single slow-binding process.

  Journal of enzyme inhibition and medicinal chemistry 20070801

• Acute methotrexate-induced encephalopathy--causal relation to homozygous allelic state for MTR c.2756A>G (D919G)?

  Journal of chemotherapy (Florence, Italy) 20070801

• [Transient leukemoid reaction of plasma cells in a patient with rheumatoid arthritis].

  [Rinsho ketsueki] The Japanese journal of clinical hematology 20070801

• The nucleoside and nucleotide mixture (OG-VI) rescues intestinal-like epithelial cells from the cytotoxicity of chemotherapeutic agents.

  The journal of medical investigation : JMI 20070801

• [Effect of chinese herbs in enhancing prednisone for treatment of refractory rheumatoid arthritis].

  Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20070801

• [Clinical value of transcervical resection under hysteroscope for placental remnants].

  Zhonghua fu chan ke za zhi 20070801

• [Serum liver tests in patients treated with methotrexate. A retrospective analysis].

  Revista medica de Chile 20070801

• A step forward in therapy for ALL in infants.

  Lancet (London, England) 20070721

• A treatment protocol for infants younger than 1 year with acute lymphoblastic leukaemia (Interfant-99): an observational study and a multicentre randomised trial.

  Lancet (London, England) 20070721

• [Adult onset Still's disease: review of 26 cases].

  Medicina clinica 20070714

• Novel boron-containing, nonclassical antifolates: synthesis and preliminary biological and structural evaluation.

  Journal of medicinal chemistry 20070712

• The dynamism of cutaneous lupus erythematosus: mild discoid lupus erythematosus evolving into SLE with SCLE and treatment-resistant lupus panniculitis.

  Clinical rheumatology 20070701

• Outcome for young children newly diagnosed with ependymoma, treated with intensive induction chemotherapy followed by myeloablative chemotherapy and autologous stem cell rescue.

  Pediatric blood & cancer 20070701

• Therapeutic responses in childhood acute lymphoblastic leukemia (ALL) and haplotypes of gamma glutamyl hydrolase (GGH) gene.

  Leukemia research 20070701

• HER-2/neu status and response to CMF: retrospective study in a series of operable breast cancer treated with primary CMF chemotherapy.

  Journal of cancer research and clinical oncology 20070701

• Changes in lipid profile during infliximab and corticosteroid treatment in rheumatoid arthritis.

  Annals of the rheumatic diseases 20070701

• Why are Dutch rheumatologists reluctant to use the COBRA treatment strategy in early rheumatoid arthritis?

  Annals of the rheumatic diseases 20070701

• Leflunomide versus methotrexate in Wegener's granulomatosis.

  Rheumatology (Oxford, England) 20070701

• Influence of molecular architecture of polyether-co-polyester dendrimers on the encapsulation and release of methotrexate.

  Biomaterials 20070701

• Effects of a treatment gap during adjuvant chemotherapy in node-positive breast cancer: results of International Breast Cancer Study Group (IBCSG) Trials 13-93 and 14-93.

  Annals of oncology : official journal of the European Society for Medical Oncology 20070701

• Pathogenetic role of myelitis for syringomyelia.

  Clinical neurology and neurosurgery 20070701

• Relapsed or refractory gestational trophoblastic neoplasia treated with the etoposide and cisplatin/etoposide, methotrexate, and actinomycin D (EP-EMA) regimen.

  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20070701

• Age of menopause among women who remain premenopausal following treatment for early breast cancer: long-term results from International Breast Cancer Study Group Trials V and VI.

  European journal of cancer (Oxford, England : 1990) 20070701

• Elevated relapse rate under oral methotrexate versus leflunomide for maintenance of remission in Wegener's granulomatosis.

  Rheumatology (Oxford, England) 20070701

• Leflunomide and methotrexate combination in refractory adult-onset Still's disease.

  The Annals of pharmacotherapy 20070701

• The effect of chemotherapy on Ki-67, Bcl-2 and Bak expression in primary tumors and lymph node metastases of breast cancer.

  Oncology reports 20070701

• Polymorphism of the DNA repair enzyme XRCC1 is associated with treatment prediction in anthracycline and cyclophosphamide/methotrexate/5-fluorouracil-based chemotherapy of patients with primary invasive breast cancer.

  Pharmacogenetics and genomics 20070701

• A case of recalcitrant necrobiosis lipoidica responding to combined immunosuppression therapy.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20070701

• Patients with moderate-to-severe plaque psoriasis preferred oral therapies to phototherapies: a preference assessment based on clinical scenarios with trade-off questions.

  Journal of clinical epidemiology 20070701

• Lymphomatoid papulosis with CD1a+ dendritic cell hyperplasia, mimicking Langerhans cell histiocytosis.

  Journal of cutaneous pathology 20070701

• Folate with methotrexate: big benefit, questionable cost.

  The British journal of dermatology 20070701

• Allogeneic transplantation for adult acute leukemia in first and second remission with a novel regimen incorporating daily intravenous busulfan, fludarabine, 400 CGY total-body irradiation, and thymoglobulin.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20070701

• Gallium imaging in a patient with tumor lysis syndrome.

  Clinical nuclear medicine 20070701

• Biphenotypic acute leukaemia: a case series.

  British journal of haematology 20070701

• A 'pre-induction course' with non-cross-reacting cytostatic drugs for rapid tumour load reduction improves outcome in adult acute lymphoblastic leukaemia.

  British journal of haematology 20070701

• Diabetes insipidus revealing an isolated pituitary stalk metastasis of breast cancer.

  European journal of neurology 20070701

• Vincristine-induced acute neurotoxicity versus Guillain-Barré syndrome: a diagnostic dilemma.

  European journal of neurology 20070701

• Maculopathy as a complication of blood-brain barrier disruption in patients with central nervous system lymphoma.

  American journal of ophthalmology 20070701

• Severe methotrexate toxicity precipitated by intravenous radiographic contrast.

  Journal of pediatric hematology/oncology 20070701

• One more change of paradigm in breast cancer treatment. Postmastectomy radiotherapy for patients with one to three lymph node metastases?

  Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] 20070701

• Outcomes in patients with active lupus nephritis requiring immunosuppressives who never received cyclophosphamide.

  The Journal of rheumatology 20070701

• Disseminated intravascular coagulation in acute leukemia at presentation and during induction therapy.

  Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20070701

• [Therapeutic strategy for type 4 gastric cancer from the clinical oncologist standpoint].

  Gan to kagaku ryoho. Cancer & chemotherapy 20070701

• [Effective combination therapy of TNF antagonists with DMARDs].

  Nihon rinsho. Japanese journal of clinical medicine 20070701

• [Economic evaluation of a new treatment for rheumatoid arthritis].

  Nihon rinsho. Japanese journal of clinical medicine 20070701

• Resveratrol inhibits rat aortic vascular smooth muscle cell proliferation via estrogen receptor dependent nitric oxide production.

  Journal of cardiovascular pharmacology 20070701

• [Discussion on the necessity of treatment of rheumatoid arthritis with integrative Chinese and Western medicine].

  Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20070701

• [Thinking on the integrative Chinese and Western medicine in treating rheumatoid arthritis].

  Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20070701

• [Effect of strengthening Pi and activating blood circulation therapy on serum levels of adrenocorticotrophic hormone and vascular endothelial growth factor in rheumatoid arthritis patients].

  Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20070701

• Design and synthesis of classical and nonclassical 6-arylthio-2,4-diamino-5-ethylpyrrolo[2,3-d]pyrimidines as antifolates.

  Journal of medicinal chemistry 20070628

• Can biology trump anatomy? Do all node-positive patients with breast cancer need chemotherapy?

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070620

• Leuprorelin acetate every-3-months depot versus cyclophosphamide, methotrexate, and fluorouracil as adjuvant treatment in premenopausal patients with node-positive breast cancer: the TABLE study.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070620

• [Medical therapy of inflammatory bowel diseases: Crohn's disease].

  Orvosi hetilap 20070617

• Clinical features and outcome of pediatric Wegener's granulomatosis.

  Arthritis and rheumatism 20070615

• A prospective study of adjuvant CMF in males with node positive breast cancer: 20-year follow-up.

  Breast cancer research and treatment 20070601

• DHFR and MSH3 co-amplification in childhood acute lymphoblastic leukaemia, in vitro and in vivo.

  Carcinogenesis 20070601

• Successful neoadjuvant synchronous chemo- and radiotherapy for disseminated primary intracranial choriocarcinoma: case report.

  Journal of neuro-oncology 20070601

• Effect of DPC 333 [(2R)-2-{(3R)-3-amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide], a human tumor necrosis factor alpha-converting enzyme inhibitor, on the disposition of methotrexate: a transporter-based drug-drug interaction case study.

  Drug metabolism and disposition: the biological fate of chemicals 20070601

• Cholesterol potentiates ABCG2 activity in a heterologous expression system: improved in vitro model to study function of human ABCG2.

  The Journal of pharmacology and experimental therapeutics 20070601

• Characterization of DNA reactive and non-DNA reactive anticancer drugs by gene expression profiling.

  Mutation research 20070601

• The contribution of methotrexate exposure and host factors on transcriptional variance in human liver.

  Toxicological sciences : an official journal of the Society of Toxicology 20070601

• Methotrexate and erythro-9-(2-hydroxynon-3-yl) adenine therapy for rat adjuvant arthritis and the effect of methotrexate on in vivo purine metabolism.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20070601

• Risk assessment in haematopoietic stem cell transplantation: GvHD prevention and treatment.

  Best practice & research. Clinical haematology 20070601

• Downregulation of the reduced folate carrier transport activity by phenobarbital-type cytochrome P450 inducers and protein kinase C activators.

  Biochimica et biophysica acta 20070601

• Biochemical and biophysical assessment of MTX-induced liver fibrosis in psoriasis patients: Fibrotest predicts the presence and Fibroscan predicts the absence of significant liver fibrosis.

  Liver international : official journal of the International Association for the Study of the Liver 20070601

• Validation of the associations between single nucleotide polymorphisms or haplotypes and responses to disease-modifying antirheumatic drugs in patients with rheumatoid arthritis: a proposal for prospective pharmacogenomic study in clinical practice.

  Pharmacogenetics and genomics 20070601

• Giant cell arteritis presenting with hemianopic visual field loss.

  Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 20070601

• Therapy with immunosuppressive drugs and biological agents and use of contraception in patients with rheumatic disease.

  The Journal of rheumatology 20070601

• Resumption of high-dose methotrexate after methotrexate-induced nephrotoxicity and carboxypeptidase G2 use.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20070601

• A clinical pharmacogenetic model to predict the efficacy of methotrexate monotherapy in recent-onset rheumatoid arthritis.

  Arthritis and rheumatism 20070601

• Moving forward in advanced bladder cancer.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070601

• Multiple sclerosis in Pakistan.

  Multiple sclerosis (Houndmills, Basingstoke, England) 20070601

• Strongyloides stercoralis hyperinfection in a patient with rheumatoid arthritis after anti-TNF-alpha therapy.

  Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20070601

• Effective etanercept treatment for psoriatic arthritis complicating concomitant human immunodeficiency virus and hepatitis C virus infection.

  The Journal of rheumatology 20070601

• [Paharmacological mechanisms of cellular immunity of overall alkali of tongbiling for the treatment of joint destruction].

  Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20070601

• CMED in the treatment of nasal natural killer cell lymphoma with distant metastases.

  Hematology (Amsterdam, Netherlands) 20070601

• Combination therapy for the treatment of multiple sclerosis: challenges and opportunities.

  Current medical research and opinion 20070601

• [MTX-HOPE (methotrexate, hydrocortisone, vincristine, sobuzoxane, and etoposide) as a low-dose salvage chemotherapy for recurrent or refractory non-Hodgkin's lymphoma].

  Gan to kagaku ryoho. Cancer & chemotherapy 20070601

• Salvage therapy and late neurotoxicity in patients with recurrent primary CNS lymphoma treated with a modified ProMACE-MOPP hybrid regimen.

  Leukemia & lymphoma 20070601

• Tacrolimus and methotrexate for the prophylaxis of graft-versus-host disease after unrelated donor cord blood transplantation for adult patients with hematologic malignancies.

  Transplantation proceedings 20070601

• Evaluation of renal function in Turkish children receiving BFM-95 therapy for acute lymphoblastic leukemia.

  Pediatric hematology and oncology 20070601

• Central nervous system anaplastic large cell lymphoma in an adult: successful treatment with a combination of radiation and chemotherapy.

  Military medicine 20070601

• Complete remission by chemotherapy in stage IE-IIE primary gastric lymphoma.

  Hepato-gastroenterology 20070601

• [2-year complete remission after withdrawal of methotrexate in a rectal methotrexate-associated diffuse large B-cell lymphoma].

  [Rinsho ketsueki] The Japanese journal of clinical hematology 20070601

• Amyopathic dermatomyositis--an uncommon presentation of dermatomyositis.

  The Israel Medical Association journal : IMAJ 20070601

• [Pulmonary infections in patients with rheumatoid arthritis].

  Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20070601

• [Synthesis of methotrexate-poly (ethylene glycol) conjugate and their anti-tumor activity in vitro].

  Yao xue xue bao = Acta pharmaceutica Sinica 20070601

• [Leflunomide as a second choice treatment in patients with rheumatoid arthritis].

  Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20070601

• Chronic idiopathic granulomatous mastitis.

  Annals of the New York Academy of Sciences 20070601

• [Clinical analysis of 108 cases with adenocarcinoma Barretts's esophagus].

  Zhonghua zhong liu za zhi [Chinese journal of oncology] 20070601

• A novel RNA silencing vector to improve antigen expression and stability in Chinese hamster ovary cells.

  Vaccine 20070516

• [Progressive epidermal and mucosal skin lesions in a patient with rheumatoid arthritis].

  Praxis 20070516

• Ancestry and pharmacogenetics of antileukemic drug toxicity.

  Blood 20070515

• Engineering small molecule specificity in nearly identical cellular environments.

  Bioorganic & medicinal chemistry letters 20070515

• Sequential combination chemotherapy in human breast cancer: a basis for increased antineoplastic activity and bone marrow protection.

  Cellular and molecular biology (Noisy-le-Grand, France) 20070515

• [Results of the SHOP LNHB98 (LMB89) trial in pediatric patients with B-cell non-Hodgkin's lymphoma].

  Medicina clinica 20070505

• Reinduction of relapsed acute promyelocytic leukemia with ATRA and low dose antimetabolite-based chemotherapy.

  Pediatric blood & cancer 20070501

• Calculated versus measured creatinine clearance for dosing methotrexate in the treatment of primary central nervous system lymphoma.

  Cancer chemotherapy and pharmacology 20070501

• Plasma homocysteine status in patients with ankylosing spondylitis.

  Clinical rheumatology 20070501

• Thirty-year follow-up of chemo/hormonal therapy in node-positive breast cancer.

  Breast cancer research and treatment 20070501

• Analysis of efficacy and toxicity of chemotherapy with cisplatin, 5-fluorouracil, methotrexate and leucovorin (PFML) and radiotherapy in the treatment of locally advanced squamous cell carcinoma of the head and neck.

  Cancer chemotherapy and pharmacology 20070501

• 'Idiopathic' eosinophilia with an Occult T-cell clone: prevalence and clinical course.

  Leukemia research 20070501

• Preliminary evaluation in rheumatoid arthritis activity in patients treated with TNF-alpha blocker plus methotrexate versus methotrexate or leflunomide alone.

  Rheumatology international 20070501

• Methotrexate induces poly(ADP-ribose) polymerase-dependent, caspase 3-independent apoptosis in subsets of proliferating CD4+ T cells.

  Clinical and experimental immunology 20070501

• The ratio of positive to excised nodes identifies high-risk subsets and reduces inter-institutional differences in locoregional recurrence risk estimates in breast cancer patients with 1-3 positive nodes: an analysis of prospective data from British Columbia and the M. D. Anderson Cancer Center.

  International journal of radiation oncology, biology, physics 20070501

• MRP2 and acquired tolerance to inorganic arsenic in the kidney of killifish (Fundulus heteroclitus).

  Toxicological sciences : an official journal of the Society of Toxicology 20070501

• Gene expression shift towards normal B cells, decreased proliferative capacity and distinct surface receptors characterize leukemic blasts persisting during induction therapy in childhood acute lymphoblastic leukemia.

  Leukemia 20070501

• Divergent cytotoxic effects of PKC412 in combination with conventional antileukemic agents in FLT3 mutation-positive versus -negative leukemia cell lines.

  Leukemia 20070501

• Increased efficacy of infliximab associated with methotrexate in ankylosing spondylitis.

  Joint, bone, spine : revue du rhumatisme 20070501

• Overactivity of the intestinal endocannabinoid system in celiac disease and in methotrexate-treated rats.

  Journal of molecular medicine (Berlin, Germany) 20070501

• Juvenile psoriatic arthritis carrying familial Mediterranean fever gene mutations in a 14-year-old Turkish girl.

  The Journal of dermatology 20070501

• [Treatment of ANCA-associated vascularitides].

  Presse medicale (Paris, France : 1983) 20070501

• Cyclosporine and tacrolimus for the treatment of rheumatoid arthritis.

  Current opinion in rheumatology 20070501

• Primary central nervous system lymphoma: biological aspects and controversies in management.

  European journal of cancer (Oxford, England : 1990) 20070501

• Does methotrexate confer a significant advantage over misoprostol alone for early medical abortion? A retrospective analysis of 8678 abortions.

  BJOG : an international journal of obstetrics and gynaecology 20070501

• Bufalin induces apoptosis in human osteosarcoma U-2OS and U-2OS methotrexate300-resistant cell lines.

  Acta pharmacologica Sinica 20070501

• Chemotherapy for osteosarcoma without high-dose methotrexate: a 12-year follow-up on 53 patients.

  Onkologie 20070501

• The antiinflammatory mechanism of methotrexate depends on extracellular conversion of adenine nucleotides to adenosine by ecto-5'-nucleotidase: findings in a study of ecto-5'-nucleotidase gene-deficient mice.

  Arthritis and rheumatism 20070501

• The folate receptor alpha is frequently overexpressed in osteosarcoma samples and plays a role in the uptake of the physiologic substrate 5-methyltetrahydrofolate.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20070501

• Renal involvement in a patient with juvenile idiopathic arthritis presenting after treatment for Hodgkin lymphoma.

  Journal of pediatric hematology/oncology 20070501

• Immuno-chemotherapy with a combination of rituximab, methotrexate, pirarubicin and procarbazine for patients with primary CNS lymphoma--a preliminary report.

  Leukemia & lymphoma 20070501

• Tissue angiotensin-converting enzyme in patients with various clinical forms of psoriasis.

  Bosnian journal of basic medical sciences 20070501

• [Clinical study of combination chemotherapy of methotrexate, epirubicin and nedaplatin (MEN) in patients with advanced urothelial carcinoma].

  Gan to kagaku ryoho. Cancer & chemotherapy 20070501

• [Three cases of necrotizing pneumonia by pseudomonas aeruginosa infection in hematological malignancy, including dead and alive cases].

  Gan to kagaku ryoho. Cancer & chemotherapy 20070501

• Painful ulcer on the breast.

  Dermatology online journal 20070501

• Rheumatoid arthritis and reproduction.

  Rheumatic diseases clinics of North America 20070501

• [Oral involvement in lymphomatoid papulosis].

  Actas dermo-sifiliograficas 20070501

• Methotrexate and risk for lymphoma.

  Archives of dermatology 20070501

• Maternal-fetal transport kinetics of methotrexate in perfused human placenta: in vitro study.

  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 20070501

• A new strategy of drug treatment in NSAID--unresponsive ankylosing spondylitis.

  The Journal of the Association of Physicians of India 20070501

• Neurologic complications associated with intrathecal liposomal cytarabine given prophylactically in combination with high-dose methotrexate and cytarabine to patients with acute lymphocytic leukemia.

  Blood 20070415

• Polychemotherapy for early breast cancer: results from the international adjuvant breast cancer chemotherapy randomized trial.

  Journal of the National Cancer Institute 20070404

• Anaplastic large cell lymphoma of bone--is it a bad tumor?

  Pediatric blood & cancer 20070401

• Pediatric primary leptomeningeal lymphoma treated without cranial radiotherapy.

  Pediatric blood & cancer 20070401

• Extramedullary infiltration at diagnosis and prognosis in children with acute myelogenous leukemia.

  Pediatric blood & cancer 20070401

• Influence of low-energy laser in the prevention of oral mucositis in children with cancer receiving chemotherapy.

  Pediatric blood & cancer 20070401

• Durability of treatment with methotrexate in Venezuelan patients with rheumatoid arthritis.

  Rheumatology international 20070401

• Results of the randomized international FAB/LMB96 trial for intermediate risk B-cell non-Hodgkin lymphoma in children and adolescents: it is possible to reduce treatment for the early responding patients.

  Blood 20070401

• Management of orbital xanthogranuloma with methotrexate.

  The British journal of ophthalmology 20070401

• Extended follow-up of methotrexate-free immunosuppression using sirolimus and tacrolimus in related and unrelated donor peripheral blood stem cell transplantation.

  Blood 20070401

• Primary central nervous system lymphoma treated with high-dose methotrexate, high-dose busulfan/thiotepa, autologous stem-cell transplantation and response-adapted whole-brain radiotherapy: results of the multicenter Ostdeutsche Studiengruppe Hamato-Onkologie OSHO-53 phase II study.

  Annals of oncology : official journal of the European Society for Medical Oncology 20070401

• Interactions of cyclosporin a with breast cancer resistance protein.

  Drug metabolism and disposition: the biological fate of chemicals 20070401

• Identification and functional assessment of BCRP polymorphisms in a Korean population.

  Drug metabolism and disposition: the biological fate of chemicals 20070401

• Characterization of the uptake of organic anion transporter (OAT) 1 and OAT3 substrates by human kidney slices.

  The Journal of pharmacology and experimental therapeutics 20070401

• High-dose methotrexate is beneficial in parenchymal brain masses of uncertain origin suspicious for primary CNS lymphoma.

  Neuro-oncology 20070401

• Survey on the use of methotrexate by pediatric rheumatologists in Canada.

  The Journal of rheumatology 20070401

• Seizure-promoting effect of blood-brain barrier disruption.

  Epilepsia 20070401

• An attempt to formulate an evidence-based strategy in the management of moderate-to-severe psoriasis: a review of the efficacy and safety of biologics and prebiologic options.

  Expert opinion on pharmacotherapy 20070401

• Gene expression profiling of rheumatoid arthritis synovial cells treated with antirheumatic drugs.

  Journal of biomolecular screening 20070401

• [Inhibition of radiographic progression in rheumatoid arthritis by anti-rheumatic drugs (DMARDs)].

  Clinical calcium 20070401

• [Filgrastim in refractory Crohn's disease with an intra-abdominal abscess].

  Gastroenterologia y hepatologia 20070401

• Role of methotrexate in the management of Crohn disease.

  Journal of pediatric gastroenterology and nutrition 20070401

• Risk factors associated with the cumulative survival of low-dose methotrexate in 273 Japanese patients with rheumatoid arthritis.

  Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20070401

• [Peripheral blood stem cell transplantation for 53 patients with malignant hematologic diseases].

  Ai zheng = Aizheng = Chinese journal of cancer 20070401

• Conventional dose intensive immunochemotherapy regimen in an adult patient with very late relapse of Burkitt's lymphoma.

  Journal of chemotherapy (Florence, Italy) 20070401

• Oral lichen planus: a case series with emphasis on therapy.

  Archives of dermatology 20070401

• [Folic acid antagonist methotrexate causes the development malformation of heart and down-regulates the BMP2b and HAS2 expressions in zebrafish].

  Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20070401

• Male breast cancer with mandibular metastasis. A case report.

  Minerva stomatologica 20070401

• Impact of FLT3 internal tandem duplications on Indian acute promyelocytic leukemia patients: prognostic implications.

  Hematology (Amsterdam, Netherlands) 20070401

• Clinical features and risk factors of pure red cell aplasia following major ABO-incompatible allogeneic hematopoietic stem cell transplantation.

  Hematology (Amsterdam, Netherlands) 20070401

• Successful umbilical cord blood transplantation using a reduced-intensity preparative regimen without total body irradiation and tacrolimus plus methotrexate for prophylaxis of graft-versus-host disease in a patient with adult T-cell leukemia/lymphoma.

  Leukemia & lymphoma 20070401

• Outcome of non-T-cell-depleted HLA-haploidentical hematopoietic stem cell transplantation from family donors in children and adolescents.

  International journal of hematology 20070401

• [Refractory proctitis].

  Gastroenterologie clinique et biologique 20070401

• Methylenetetrahydrofolate reductase C677T and A1298C gene variants in adult non-Hodgkin's lymphoma patients: association with toxicity and survival.

  Haematologica 20070401

• Developmental changes of aldehyde oxidase in postnatal rat liver.

  Drug metabolism and pharmacokinetics 20070401

• Controlled release of methotrexate from w/o microemulsion and its in vitro antitumor activity.

  Drug delivery 20070401

• Adverse events of MVAC chemotherapy in patients with advanced urothelial cancer of the bladder.

  Hinyokika kiyo. Acta urologica Japonica 20070401

• [Early relapse of Burkitt's lymphoma with t(8;14) and t(14;18) after rituximab-combined CODOX-M and IVAC therapy].

  [Rinsho ketsueki] The Japanese journal of clinical hematology 20070401

• [Diagnosis and treatment of relapsing polychondritis].

  Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20070401

• [Diagnosis and prognosis study of breast carcinoma with micropapillary component].

  Zhonghua bing li xue za zhi = Chinese journal of pathology 20070401

• Clinical manifestations and treatment of rheumatoid pachymeningitis.

  Neurology 20070327

• Adjuvant therapy for early breast cancer.

  The New England journal of medicine 20070322

• Effect of DC/mDC iontophoresis and terpenes on transdermal permeation of methotrexate: in vitro study.

  International journal of pharmaceutics 20070321

• Highly efficient ligands for dihydrofolate reductase from Cryptosporidium hominis and Toxoplasma gondii inspired by structural analysis.

  Journal of medicinal chemistry 20070308

• Human constitutive androstane receptor mediated methotrexate induction of human dehydroepiandrosterone sulfotransferase (hSULT2A1).

  Toxicology 20070307

• T-cell acute lymphoblastic leukemia relapsing as acute myelogenous leukemia.

  Pediatric blood & cancer 20070301

• Autologous transplantation of CD133 selected hematopoietic progenitor cells for treatment of relapsed acute lymphoblastic leukemia.

  Pediatric blood & cancer 20070301

• Psoriatic arthritis and Klinefelter syndrome: case report.

  Clinical rheumatology 20070301

• Adolescents with acute lymphoblastic leukaemia: outcome on UK national paediatric (ALL97) and adult (UKALLXII/E2993) trials.

  Pediatric blood & cancer 20070301

• Trilateral retinoblastoma.

  Pediatric blood & cancer 20070301

• Improved outcome in childhood acute myeloid leukemia in Singapore with the MRC AML 10 protocol.

  Pediatric blood & cancer 20070301

• Molecular basis for decreased folylpoly-gamma-glutamate synthetase expression in a methotrexate resistant CCRF-CEM mutant cell line.

  Leukemia research 20070301

• Autoantibodies, metalloproteinases and bone markers in rheumatoid arthritis patients are unable to predict their responses to infliximab.

  Rheumatology (Oxford, England) 20070301

• Local recurrence and distant metastasis of supratentorial primitive neuro-ectodermal tumor in an adult patient successfully treated with intensive induction chemotherapy and maintenance temozolomide.

  Journal of neuro-oncology 20070301

• Recurrence rates after DCE-MRI image guided planning for breast-conserving surgery following neoadjuvant chemotherapy for locally advanced breast cancer patients.

  European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 20070301

• A validation of the most commonly used protocol to predict the success of single-dose methotrexate in the treatment of ectopic pregnancy.

  Human reproduction (Oxford, England) 20070301

• Methotrexate regulates the expression of glucocorticoid receptor alpha and beta isoforms in normal human peripheral mononuclear cells and human lymphocyte cell lines in vitro.

  Molecular immunology 20070301

• Effect of age and radiation dose on local control after breast conserving treatment: EORTC trial 22881-10882.

  Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20070301

• High-risk gestational trophoblastic neoplasia with brain metastases: individualized multidisciplinary therapy in the management of four patients.

  Gynecologic oncology 20070301

• The role of intrathecal chemotherapy prophylaxis in patients with diffuse large B-cell lymphoma.

  Annals of oncology : official journal of the European Society for Medical Oncology 20070301

• Ultraviolet recall reaction after total body irradiation, etoposide, and methotrexate therapy.

  Journal of the American Academy of Dermatology 20070301

• Evidence of a novel antiapoptotic factor: role of inhibitor of differentiation or DNA binding (Id-1) in anticancer drug-induced apoptosis.

  Cancer science 20070301

• SFOP OS94: a randomised trial comparing preoperative high-dose methotrexate plus doxorubicin to high-dose methotrexate plus etoposide and ifosfamide in osteosarcoma patients.

  European journal of cancer (Oxford, England : 1990) 20070301

• Cryotherapy in the prevention of oral mucositis in patients receiving low-dose methotrexate following myeloablative allogeneic stem cell transplantation: a prospective randomized study of the Gruppo Italiano Trapianto di Midollo Osseo nurses group.

  Bone marrow transplantation 20070301

• Alternatives to mifepristone for early medical abortion.

  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20070301

• Is the benefit of postmastectomy irradiation limited to patients with four or more positive nodes, as recommended in international consensus reports? A subgroup analysis of the DBCG 82 b&c randomized trials.

  Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20070301

• Improved outcome from substituting methotrexate with epirubicin: results from a randomised comparison of CMF versus CEF in patients with primary breast cancer.

  European journal of cancer (Oxford, England : 1990) 20070301

• Evaluation of the contribution of the nasal cavity and gastrointestinal tract to drug absorption following nasal application to rats.

  Biological & pharmaceutical bulletin 20070301

• Donor lymphocyte infusion for the treatment of leukemia relapse after HLA-mismatched/haploidentical T-cell-replete hematopoietic stem cell transplantation.

  Haematologica 20070301

• Disseminated necrotizing leukoencephalopathy following low-dose oral methotrexate.

  European journal of neurology 20070301

• Medical therapy for ectopic pregnancy.

  Seminars in reproductive medicine 20070301

• Local treatment of ectopic pregnancy.

  Seminars in reproductive medicine 20070301

• [A case of meningeal carcinomatosis from lung cancer successfully treated with aggressive multimodal therapy].

  Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20070301

• HLA-DR protein status predicts survival in patients with diffuse large B-cell lymphoma treated on the MACOP-B chemotherapy regimen.

  Leukemia & lymphoma 20070301

• CODOX-M/IVAC (NCI 89-C-41) in children and adolescents with Burkitt's leukemia/lymphoma and large B-cell lymphomas: a 15-year monocentric experience.

  Leukemia & lymphoma 20070301

• Kluver-Bucy syndrome in a boy with non-Hodgkin lymphoma.

  Pediatric hematology and oncology 20070301

• [Development and application of screening method for steroid dihydrofolate reductase inhibitors by high performance capillary electrophoresis].

  Se pu = Chinese journal of chromatography 20070301

• A new strategy of drug treatment in NSAID-unresponsive ankylosing spondylitis: combination of pamidronate and methylprednisolone monthly intravenous infusions on the background of a combination of disease modifying drugs sulfasalazine and methotrexate.

  The Journal of the Association of Physicians of India 20070301

• Ocular myositis: diagnostic assessment, differential diagnoses, and therapy of a rare muscle disease - five new cases and review.

  Clinical ophthalmology (Auckland, N.Z.) 20070301

• Chiral recognition of amethopterin enantiomers by the reduced folate carrier in Caco-2 cells.

  Drug metabolism and pharmacokinetics 20070225

• Proteomic analysis identifies candidate proteins associated with distant recurrences in breast cancer after adjuvant chemotherapy.

  Journal of pharmaceutical and biomedical analysis 20070219

• Enhanced chemotherapy delivery by intraarterial infusion and blood-brain barrier disruption in the treatment of cerebral metastasis.

  Cancer 20070215

• Methotrexate as a corticosteroid-sparing agent in complicated neurocysticercosis.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20070215

• [Management recommendations in patients with methotrexate intoxication].

  Nederlands tijdschrift voor geneeskunde 20070210

• Diastolic function of the heart in mixed connective tissue disease.

  Clinical rheumatology 20070201

• ABCC10, ABCC11, and ABCC12.

  Pflugers Archiv : European journal of physiology 20070201

• Combination therapy with sulfasalazine and methotrexate is more effective than either drug alone in patients with rheumatoid arthritis with a suboptimal response to sulfasalazine: results from the double-blind placebo-controlled MASCOT study.

  Annals of the rheumatic diseases 20070201

• The impact of age in the outcome of patients with advanced or recurrent cervical cancer after platinum-based chemotherapy.

  Gynecologic oncology 20070201

• Results of the PETHEMA ALL-96 trial in elderly patients with Philadelphia chromosome-negative acute lymphoblastic leukemia.

  European journal of haematology 20070201

• Use of '2-dose' regimen of methotrexate to treat ectopic pregnancy.

  Fertility and sterility 20070201

• Neoadjuvant chemotherapy for radioinduced osteosarcoma of the extremity: The Rizzoli experience in 20 cases.

  International journal of radiation oncology, biology, physics 20070201

• Methotrexate gamma-hydroxamate derivatives as potential dual target antitumor drugs.

  Bioorganic & medicinal chemistry 20070201

• Age and high-dose methotrexate are associated to clinical acute encephalopathy in FRALLE 93 trial for acute lymphoblastic leukemia in children.

  Leukemia 20070201

• Myelopathy due to intrathecal chemotherapy: magnetic resonance imaging findings.

  Clinical radiology 20070201

• Progressive myopathy with up-regulation of MHC-I associated with statin therapy.

  Neuromuscular disorders : NMD 20070201

• Intravenous busulfan and melphalan, tacrolimus, and short-course methotrexate followed by unmodified HLA-matched related or unrelated hematopoietic stem cell transplantation for the treatment of advanced hematologic malignancies.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20070201

• Tailoring biological treatment: anakinra treatment of posterior uveitis associated with the CINCA syndrome.

  The British journal of ophthalmology 20070201

• Bio-pathologic characteristics related to chromosome 11 aneusomy and cyclin D1 gene status in surgically resected stage I and II breast cancer: Identification of an adverse prognostic profile.

  The American journal of surgical pathology 20070201

• Caffeine consumption and methotrexate dosing requirement in psoriasis and psoriatic arthritis.

  International journal of dermatology 20070201

• Evaluation of oral methotrexate in the treatment of systemic sclerosis.

  International journal of dermatology 20070201

• [Mandibular chloroma].

  Revue de stomatologie et de chirurgie maxillo-faciale 20070201

• Exploratory analysis of four polymorphisms in human GGH and FPGS genes and their effect in methotrexate-treated rheumatoid arthritis patients.

  Pharmacogenomics 20070201

• Anticipatory nausea: the role of individual differences related to sensory perception and autonomic reactivity.

  Annals of behavioral medicine : a publication of the Society of Behavioral Medicine 20070201

• [Pharmacogenomics of antirheumatic drugs and personalized medicine for rheumatoid arthritis].

  Nihon rinsho. Japanese journal of clinical medicine 20070201

• Transverse myelopathy following intrathecal administration of chemotherapy.

  Singapore medical journal 20070201

• N-of-1 trial of low-dose methotrexate and/or prednisolone in lieu of anti-CCP, MRI, or ultrasound, as first option in suspected rheumatoid arthritis?

  The Journal of rheumatology 20070201

• Serologically HLA-DR-mismatched unrelated donors might provide a valuable alternative in allogeneic transplantation: experience from a single japanese institution.

  International journal of hematology 20070201

• Novel therapies for sarcoidosis.

  Seminars in respiratory and critical care medicine 20070201

• Levofloxacin treatment in patients with rheumatoid arthritis receiving methotrexate.

  Southern medical journal 20070201

• The use of biological agents in the treatment of rheumatoid arthritis.

  Annals of the Academy of Medicine, Singapore 20070201

• Disease-modifying antirheumatic drug use in the elderly rheumatoid arthritis patient.

  Rheumatic diseases clinics of North America 20070201

• EGFP fluorescence as an indicator of cancer cells response to methotrexate.

  European journal of pharmacology 20070126

• [Main symptom: chronic deep back pain. Do you know the signs of Bechterew disease?].

  MMW Fortschritte der Medizin 20070125

• Adjuvant chemotherapy followed by goserelin compared with either modality alone: the impact on amenorrhea, hot flashes, and quality of life in premenopausal patients--the International Breast Cancer Study Group Trial VIII.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070120

• Final results of a prospective clinical trial with VAMP and low-dose involved-field radiation for children with low-risk Hodgkin's disease.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070120

• Lost in transcription.

  The New England journal of medicine 20070118

• Prognostic role of the reduced folate carrier, the major membrane transporter for methotrexate, in childhood acute lymphoblastic leukemia: a report from the Children's Oncology Group.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20070115

• Pulses of vincristine and dexamethasone in addition to intensive chemotherapy for children with intermediate-risk acute lymphoblastic leukaemia: a multicentre randomised trial.

  Lancet (London, England) 20070113

• [Guideline 'Leptomeningeal metastases of solid tumours'].

  Nederlands tijdschrift voor geneeskunde 20070113

• Structure-activity relationship study of prion inhibition by 2-aminopyridine-3,5-dicarbonitrile-based compounds: parallel synthesis, bioactivity, and in vitro pharmacokinetics.

  Journal of medicinal chemistry 20070111

• Retroperitoneal fibrosis after chemotherapy.

  European urology 20070101

• The incidence of pancytopenia in patients taking leflunomide alone or with methotrexate.

  Pharmacoepidemiology and drug safety 20070101

• The effects of N-acetylcysteine on methotrexate-induced oxidative renal damage in rats.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070101

• Method for the determination of blood methotrexate by high performance liquid chromatography with online post-column electrochemical oxidation and fluorescence detection.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070101

• Concurrent radiotherapy and capecitabine, followed by high-dose methotrexate consolidation, provided effective palliation in a patient with leptomeningeal metastases from breast cancer.

  Annals of oncology : official journal of the European Society for Medical Oncology 20070101

• In silico prediction of pregnane X receptor activators by machine learning approaches.

  Molecular pharmacology 20070101

• Androgen induces expression of the multidrug resistance protein gene MRP4 in prostate cancer cells.

  Prostate cancer and prostatic diseases 20070101

• Interaction of nonsteroidal anti-inflammatory drugs with multidrug resistance protein (MRP) 2/ABCC2- and MRP4/ABCC4-mediated methotrexate transport.

  The Journal of pharmacology and experimental therapeutics 20070101

• The effect of low pH on breast cancer resistance protein (ABCG2)-mediated transport of methotrexate, 7-hydroxymethotrexate, methotrexate diglutamate, folic acid, mitoxantrone, topotecan, and resveratrol in in vitro drug transport models.

  Molecular pharmacology 20070101

• Short-term methotrexate could reduce early immune reactions and improve outcomes in umbilical cord blood transplantation for adults.

  Bone marrow transplantation 20070101

• Severe acute toxicity associated with high-dose methotrexate (MTX) therapy: use of therapeutic drug monitoring and test-dose to guide carboxypeptidase G2 rescue and MTX continuation.

  European journal of clinical pharmacology 20070101

• Combination chemotherapy followed by autologous stem cell transplant for enteropathy-associated T cell lymphoma.

  British journal of haematology 20070101

• Adult-onset Still's disease in a patient over 80 years old successfully treated with low-dose methotrexate therapy.

  Age and ageing 20070101

• Reactivation of hepatitis in a bladder cancer patient receiving chemotherapy.

  International urology and nephrology 20070101

• The influence of cyclosporin alone, or cyclosporin and methotrexate, on the incidence of mixed haematopoietic chimaerism following allogeneic sibling bone marrow transplantation for severe aplastic anaemia.

  Bone marrow transplantation 20070101

• Genetic polymorphisms associated with adverse events and elimination of methotrexate in childhood acute lymphoblastic leukemia and malignant lymphoma.

  Journal of human genetics 20070101

• Cutaneous sarcoidosis therapy updated.

  Journal of the American Academy of Dermatology 20070101

• Feasibility of concurrent adjuvant chemotherapy and radiotherapy after breast-conserving surgery in early breast cancer.

  Journal of surgical oncology 20070101

• Clinical practice format for choosing a second-line disease modifying anti-rheumatic drug in early rheumatoid arthritis after failure of 6 months' first-line DMARD therapy.

  Joint, bone, spine : revue du rhumatisme 20070101

• Clinicopathologic features and results of transcatheter arterial chemoembolization for osteosarcoma.

  Cardiovascular and interventional radiology 20070101

• Drug Insight: resistance to methotrexate and other disease-modifying antirheumatic drugs--from bench to bedside.

  Nature clinical practice. Rheumatology 20070101

• Practical issues and challenges in the diagnosis and treatment of pulmonary sarcoidosis.

  Drugs 20070101

• [Predictive role of diagnostic information in treatment efficacy of rheumatoid arthritis based on neural network model analysis].

  Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20070101

• [Chemotherapy in advanced gastric cancer--to ensure timely and appropriate switch to subsequent treatment options].

  Gan to kagaku ryoho. Cancer & chemotherapy 20070101

• [Concurrent chemo-radiotherapy for localized refractory non-Hodgkin's lymphoma--report of two cases].

  Gan to kagaku ryoho. Cancer & chemotherapy 20070101

• MRP8/ABCC11 directly confers resistance to 5-fluorouracil.

  Molecular cancer therapeutics 20070101

• Osteosarcoma (osteogenic sarcoma).

  Orphanet journal of rare diseases 20070101

• On the action of methotrexate and 6-mercaptopurine on M. avium subspecies paratuberculosis.

  PloS one 20070101

• Prevention of high-dose-methotrexate neurotoxicity by adequate folinic acid rescue is possible even after central nervous system irradiation.

  Medical hypotheses 20070101

• Scientific basis for the efficacy of combined use of antirheumatic drugs against bone destruction in rheumatoid arthritis.

  Modern rheumatology 20070101

• Paclitaxel with cisplatin as salvage treatment for patients with previously treated advanced transitional cell carcinoma of the urothelial tract.

  Neoplasia (New York, N.Y.) 20070101

• [Outcome of gestational trophoblastic neoplasia patients with residual lung tumor after completion of treatment].

  Zhonghua fu chan ke za zhi 20070101

• A small animal positron emission tomography study of the effect of chemotherapy and hormonal therapy on the uptake of 2-deoxy-2-[F-18]fluoro-D-glucose in murine models of breast cancer.

  Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20070101

• [High dose methotrexate induced acute renal insufficiency in a patient with acute lymphoblastic leukemia].

  Zhonghua er ke za zhi = Chinese journal of pediatrics 20070101

• The potential benefits of green tea in patients with uveitis.

  Medical hypotheses 20070101

• Sulfasalazine-induced reduction of glutathione levels in breast cancer cells: enhancement of growth-inhibitory activity of Doxorubicin.

  Chemotherapy 20070101

• Treatment of vulvovaginal erosive and stenosing lichen planus by surgical dilatation and methotrexate.

  Acta obstetricia et gynecologica Scandinavica 20070101

• Mastoiditis complicated with Gradenigo syndrome and a hypertrophic pachymeningitis with consequent communicating hydrocephalus.

  Acta oto-laryngologica 20070101

• Difference in preventive effects between the phosphodiesterase iv inhibitor rolipram and anti-arthritic drugs on antigen-induced arthritis in mice.

  Immunological investigations 20070101

• Surgery for hypotony in patients with juvenile idiopathic arthritis-associated uveitis.

  Ocular immunology and inflammation 20070101

• Necrotising anterior scleritis in a late-onset rheumatoid arthritis (LORA) patient.

  Ocular immunology and inflammation 20070101

• [Diabetic ketoacidosis responsive to methotrexate in a patient with a mixed connective tissue disease].

  Revista medica de Chile 20070101

• Efalizumab for the treatment of psoriatic arthritis.

  Journal of cutaneous medicine and surgery 20070101

• Intracerebral hemorrhage as initial presentation of gestational choriocarcinoma: a case report and literature review.

  International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20070101

• [Anakinra, a recombinant human IL-1 receptor antagonist, in clinical practice. Outcome in 60 patients with severe rheumatoid arthritis].

  Reumatismo 20070101

• A relationship between pharmacokinetics (PK) and the efficacy of infliximab for patients with rheumatoid arthritis: characterization of infliximab-resistant cases and PK-based modified therapy.

  Modern rheumatology 20070101

• Influence of methotrexate dose on its efficacy and safety in rheumatoid arthritis patients: evidence based on the variety of prescribing approaches among practicing Japanese rheumatologists in a single institute-based large observational cohort (IORRA).

  Modern rheumatology 20070101

• A case of life-threatening refractory polychondritis successfully treated with combined intensive immunosuppressive therapy with methotrexate.

  Modern rheumatology 20070101

• Antifolate pseudo-resistance due to elevated levels of thymidine and hypoxanthine in a commercial serum preparation.

  Anticancer research 20070101

• Prognostic impact of haemoglobin levels in breast cancer.

  Anticancer research 20070101

• Flow-injection-electrochemical oxidation fluorimetry for determination of methotrexate.

  Luminescence : the journal of biological and chemical luminescence 20070101

• Rheumatoid arthritis patients with therapy-induced myelodysplastic syndrome present with long-term remission after recovery.

  Scandinavian journal of rheumatology 20070101

• [Influence of antitumor preparations on the concentration of free radicals in cells of Fusarium bulbigenum var. blasticola fungus during primary and tumour-like secondary growth].

  Biofizika 20070101

• Effect of adjuvant systemic treatment on cosmetic outcome and late normal-tissue reactions after breast conservation.

  Acta oncologica (Stockholm, Sweden) 20070101

• Chronic anemia and thrombocytosis as the initial presentation of Still's disease in an elderly patient.

  Gerontology 20070101

• [Case of methotrexate encephalopathy: findings on diffusion tensor image and correlation with clinical outcome].

  Rinsho shinkeigaku = Clinical neurology 20070101

• Daunorubicin-induced cell kill with 1-hour versus 24-hour infusions: a randomized comparison in children with newly diagnosed acute lymphoblastic leukemia.

  Klinische Padiatrie 20070101

• Prognostic markers of clinical remission in early rheumatoid arthritis after two years of DMARDs in a clinical setting.

  Clinical and experimental rheumatology 20070101

• Systemic immunomodulatory therapy in severe dry eye secondary to inflammation.

  Ocular immunology and inflammation 20070101

• Evidence-based therapy for cutaneous sarcoidosis.

  Clinics in dermatology 20070101

• Tumour dormancy in breast cancer: an update.

  Breast cancer research : BCR 20070101

• Methotrexate pneumonia lacking dyspnea and radiographic interstitial patterns during treatment for early rheumatoid arthritis: bronchoalveolar lavage and transbronchial lung biopsy in a differential diagnosis.

  Modern rheumatology 20070101

• [Modified BFM-90 regimen greatly improves treatment outcomes of chinese childhood and adolescent lymphoblastic lymphoma].

  Zhonghua zhong liu za zhi [Chinese journal of oncology] 20070101

• Genome position and gene amplification.

  Genome biology 20070101

• New classification system-based visual outcome in Eales' disease.

  Indian journal of ophthalmology 20070101

• A 1-year case-control study in patients with rheumatoid arthritis indicates prevention of loss of bone mineral density in both responders and nonresponders to infliximab.

  Arthritis research & therapy 20070101

• [Treatment of thyroid ophthalmopathy--a clinical case].

  Oftalmologia (Bucharest, Romania : 1990) 20070101

• Pharmacokinetic comparisons of tail-bleeding with cannula- or retro-orbital bleeding techniques in rats using six marketed drugs.

  Journal of pharmacological and toxicological methods 20070101

• Psychological side effects of MTX treatment in juvenile idiopathic arthritis: a pilot study.

  Clinical and experimental rheumatology 20070101

• Celastrus aculeatus Merr. suppresses the induction and progression of autoimmune arthritis by modulating immune response to heat-shock protein 65.

  Arthritis research & therapy 20070101

• Angular-interstitial pregnancy treated with minimally invasive surgery after adjuvant methotrexate medical therapy.

  JSLS : Journal of the Society of Laparoendoscopic Surgeons 20070101

• Effects of raloxifene on development of the methotrexate-induced changes in bone mechanical properties of male rats.

  Pharmacological reports : PR 20070101

• A paediatric case of Candida pericarditis and eosophagus stricture during treatment for acute lymphatic leukaemia.

  Acta oncologica (Stockholm, Sweden) 20070101

• Rheumatoid arthritis treatment and the risk of severe interstitial lung disease.

  Scandinavian journal of rheumatology 20070101

• Right bundle branch block induced by low-dose methotrexate in a patient with rheumatoid arthritis.

  Scandinavian journal of rheumatology 20070101

• [Modern chemotherapy of invasive bladder cancer].

  Magyar onkologia 20070101

• Successful treatment with infliximab and low-dose methotrexate in a Japanese patient with familial Mediterranean fever.

  Internal medicine (Tokyo, Japan) 20070101

• [Intrathecal chemotherapy treatment of neoplastic meningitis from solid tumors using liposomal cytarabine: experience at the Istituto Regina Elena di Roma].

  Tumori 20070101

• Intravenous immunoglobulins: a valuable asset in the treatment of a case of septic febrile ulceronecrotic Mucha-Habermann disease.

  Dermatology (Basel, Switzerland) 20070101

• Juvenile idiopathic oligoarthritis: analysis of 42 cases in Jordan.

  Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit 20070101

• Higher maximal serum concentration of methotrexate predicts the incidence of adverse reactions in Japanese rheumatoid arthritis patients.

  Modern rheumatology 20070101

• Methotrexate conjugated to gold nanoparticles inhibits tumor growth in a syngeneic lung tumor model.

  Molecular pharmaceutics 20070101

• Staphylococcus aureus thymic abscesses associated with anti-tumour necrosis factor therapy.

  Scandinavian journal of rheumatology 20070101

• [The results of a multicenter trial of acute lymphoblastic leukemia treatment on ALL-MB 91/ALL-BFM 90m in children: analysis of efficacy and toxicity].

  Terapevticheskii arkhiv 20070101

• Conventional therapies for psoriasis.

  Reumatismo 20070101

• Conventional therapy of psoriatic arthritis: evidence-based review.

  Reumatismo 20070101

• [Gemcitabine and pemetrexed in genito-urinary tumors treatment].

  Bulletin du cancer 20070101

• Methotrexate delivery to the eye using transscleral hydrogel iontophoresis.

  Current eye research 20070101

• Comparison of 2-methoxyestradiol and methotrexate effects on non-Hodgkin's B-cell lymphoma.

  Current eye research 20070101

• Methotrexate versus hydroxycarbamide (hydroxyurea) as a weekly dose to treat moderate-to-severe chronic plaque psoriasis: a comparative study.

  The Journal of dermatological treatment 20070101

• Methotrexate-betamethasone weekly oral pulse in psoriasis.

  The Journal of dermatological treatment 20070101

• Gene signatures developed from patient tumor explants grown in nude mice to predict tumor response to 11 cytotoxic drugs.

  Cancer genomics & proteomics 20070101

• [Response to anti-TNF-alpha treatment for secondary renal amyloidosis in a patient with ankylosing spondylitis].

  Reumatismo 20070101

• Chemotherapy-induced nausea, vomiting, and fatigue--the role of individual differences related to sensory perception and autonomic reactivity.

  Psychotherapy and psychosomatics 20070101

• Understanding the mechanisms of action of methotrexate: implications for the treatment of rheumatoid arthritis.

  Bulletin of the NYU hospital for joint diseases 20070101

• Vasculitis update, 2007.

  Bulletin of the NYU hospital for joint diseases 20070101

• Methotrexate reduces the levels of pentosidine and 8-hydroxy-deoxy guanosine in patients with rheumatoid arthritis.

  Modern rheumatology 20070101

• Does HER2 immunoreactivity provide prognostic information in locally advanced urothelial carcinoma patients receiving adjuvant M-VEC chemotherapy?

  Urologia internationalis 20070101

• Acral erythema with oral methotrexate in a child.

  Pediatric dermatology 20070101

• Aminotransferases are associated with insulin resistance and atherosclerosis in rheumatoid arthritis.

  BMC cardiovascular disorders 20070101

• Methotrexate in dermatology.

  Dermatologic therapy 20070101

• Cobalamin potentiates vinblastine cytotoxicity through downregulation of mdr-1 gene expression in HepG2 cells.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20070101

• Wegener's granulomatosis with extension to the cavernous sinus.

  The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society 20070101

• Morphine in children with cancer: impact of age, chemotherapy and other factors on protein binding.

  Journal of pain & palliative care pharmacotherapy 20070101

• [Antirheumatoid activity of methotrexate in phospholipid nanoparticles (Phosphogliv)].

  Biomeditsinskaia khimiia 20070101

• The therapy of Sjogren's syndrome: a review.

  La Clinica terapeutica 20070101

• Serum IL-1beta levels are associated with the presence of erosions in recent onset rheumatoid arthritis.

  Clinical and experimental rheumatology 20070101

• Gynecomastia associated with low-dose methotrexate therapy for rheumatoid arthritis.

  Modern rheumatology 20070101

• Switching the therapy from etanercept to infliximab in a child with rheumatoid factor positive polyarticular juvenile idiopathic arthritis.

  Modern rheumatology 20070101

• Acute lymphoblastic leukemia in a patient with chronic cyanoacrylate exposure.

  Acta haematologica 20070101

• Adverse drug interactions involving common prescription and over-the-counter analgesic agents.

  Clinical therapeutics 20070101

• Leflunomide in psoriatic arthritis: a retrospective study of discontinuation rate in daily clinical practice compared with methotrexate.

  Clinical and experimental rheumatology 20070101

• Delayed neutrophil apoptosis in very early rheumatoid arthritis patients is abrogated by methotrexate therapy.

  Clinical and experimental rheumatology 20070101

• Fatal hepatic failure associated with hepatitis B virus reactivation in a hepatitis B surface antigen-negative patient with rheumatoid arthritis receiving low dose methotrexate.

  Clinical and experimental rheumatology 20070101

• Methotrexate/naproxen-associated severe hepatitis in a child with juvenile idiopathic arthritis.

  Clinical and experimental rheumatology 20070101

• Evaluation of the prognostic and predictive value of HER-1/EGFR in breast cancer patients participating in a randomized study with dose-dense sequential adjuvant chemotherapy.

  Oncology 20070101

• Sequence-dependent administration of 5-fluorouracil maintains methotrexate antineoplastic activity in human estrogen-negative breast cancer and protects against methotrexate cytotoxicity in human bone marrow.

  Anticancer research 20070101

• Radiographic and histological evaluation of bisphosphonate alendronate and metotrexate effects on rat mandibles inoculated with Walker 256 carcinosarcoma.

  Acta cirurgica brasileira 20070101

• Serpiginous choroiditis treated in a stepladder approach.

  Bulletin de la Societe belge d'ophtalmologie 20070101

• In vitro chemosensitivity profile of oral squamous cell cancer and its correlation with clinical response to chemotherapy.

  Indian journal of cancer 20070101

• Inappropriate doses of chemotherapy in Italian breast cancer patients enrolled in clinical trials.

  Tumori 20070101

• Rheumatoid arthritis.

  BMJ clinical evidence 20070101

• [Security of the combined treatment of methotrexate and leflunomide in patients with rheumatoid arthritis].

  Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina) 20070101

• Targeted brain tumor treatment-current perspectives.

  Drug target insights 20070101

• Body mass index does not influence pharmacokinetics or outcome of treatment in children with acute lymphoblastic leukemia.

  Blood 20061215

• Synthesis, dihydrofolate reductase inhibition, antitumor testing, and molecular modeling study of some new 4(3H)-quinazolinone analogs.

  Bioorganic & medicinal chemistry 20061215

• Synthesis and evaluation of a classical 2,4-diamino-5-substituted-furo[2,3-d]pyrimidine and a 2-amino-4-oxo-6-substituted-pyrrolo[2,3-d]pyrimidine as antifolates.

  Bioorganic & medicinal chemistry 20061215

• Pentose phosphate cycle oxidative and nonoxidative balance: A new vulnerable target for overcoming drug resistance in cancer.

  International journal of cancer 20061215

• [Psoriasis].

  La Revue du praticien 20061215

• Methotrexate induces seizure and decreases glutamate uptake in brain slices: prevention by ionotropic glutamate receptors antagonists and adenosine.

  Life sciences 20061203

• Absorption of folate by Caco-2 cells is not affected by high glucose concentration.

  European journal of pharmacology 20061203

• Panmucositis and chemosensitisation associated with betel quid chewing during dose-dense adjuvant breast cancer chemotherapy.

  Cancer chemotherapy and pharmacology 20061201

• Combination chemotherapy with 5-fluorouracil, methotrexate and etoposide for patients with high-risk gestational trophoblastic tumors: a report based on our 11-year clinical experiences.

  Gynecologic oncology 20061201

• Purpura and serum mixed cryoglobulinemia in psoriatic arthritis.

  Rheumatology international 20061201

• Retention time for corticosteroid-sparing systemic immunosuppressive agents in patients with inflammatory eye disease.

  The British journal of ophthalmology 20061201

• Juvenile dermatomyositis with a rare and remarkable complication: sinus bradycardia.

  Rheumatology international 20061201

• Misoprostol alone vs. methotrexate followed by misoprostol for early abortion.

  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20061201

• Low mortality of children undergoing hematopoietic stem cell transplantation from 7 to 8/10 human leukocyte antigen allele-matched unrelated donors with the use of antithymocyte globulin.

  Bone marrow transplantation 20061201

• Update on the medical treatment of juvenile idiopathic arthritis.

  Current rheumatology reports 20061201

• The nonsurgical management of ectopic pregnancy.

  Current opinion in obstetrics & gynecology 20061201

• Primary tumor levels of tissue inhibitor of metalloproteinases-1 are predictive of resistance to chemotherapy in patients with metastatic breast cancer.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20061201

• Mediastinal follicular dendritic cell sarcoma involving bone marrow: a case report and review of the literature.

  Annals of diagnostic pathology 20061201

• Identification of an intestinal folate transporter and the molecular basis for hereditary folate malabsorption.

  Cell 20061201

• Topotecan and methotrexate alter expression of the apoptosis-related genes BCL2, FAS and BCL2L12 in leukemic HL-60 cells.

  Biological chemistry 20061201

• [Breast cancer in young women in the south of Tunisia].

  Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique 20061201

• [Localized scleroderma (morphea)].

  Presse medicale (Paris, France : 1983) 20061201

• Comparable outcomes of matched-related and alternative donor stem cell transplantation for pediatric severe aplastic anemia.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20061201

• Conservative treatment with transurethral resection, neoadjuvant chemotherapy followed by radiochemotherapy in stage T2-3 transitional bladder cancer.

  Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20061201

• Is mega dose of methotrexate beneficial to patients with acute lymphoblastic leukemia?

  Leukemia & lymphoma 20061201

• Severe gastrointestinal inflammation in adult dermatomyositis: characterization of a novel clinical association.

  The American journal of the medical sciences 20061201

• [Porokeratosis in a patient with dermatomyositis].

  Actas dermo-sifiliograficas 20061201

• Alkaline comet assay study with breast cancer patients: evaluation of baseline and chemotherapy-induced DNA damage in non-target cells.

  Clinical and experimental medicine 20061201

• Childhood CD4+/CD56+ hematodermic neoplasm: case report and review of the literature.

  Haematologica 20061201

• Long-term follow-up of autologous peripheral blood stem cell transplantation in the treatment of a patient with acute panmyelosis with myelofibrosis.

  Haematologica 20061201

• Favourable outcome in an APL patient with PLZF/RARalpha fusion gene: quantitative real-time RT-PCR confirms molecular response.

  Haematologica 20061201

• In vivo-in vitro relationship of methotrexate 7-hydroxylation by aldehyde oxidase in four different strain rats.

  Drug metabolism and pharmacokinetics 20061201

• [Superior sagittal sinus thrombosis during remission induction therapy for acute lymphoblastic leukemia].

  [Rinsho ketsueki] The Japanese journal of clinical hematology 20061201

• Adverse drug reaction to methotrexate: pharmacogenetic origin.

  The Journal of the American Osteopathic Association 20061201

• Effects of N-acetylcysteine on methotrexate-induced small intestinal damage in rats.

  The Mount Sinai journal of medicine, New York 20061201

• Treatment of Burkitt lymphoma in children and adults: Lessons from Africa.

  Current hematologic malignancy reports 20061201

• A 2.13 A structure of E. coli dihydrofolate reductase bound to a novel competitive inhibitor reveals a new binding surface involving the M20 loop region.

  Journal of medicinal chemistry 20061130

• [The immunology of psoriasis: from basic research to the bedside].

  Orvosi hetilap 20061119

• Epirubicin and cyclophosphamide, methotrexate, and fluorouracil as adjuvant therapy for early breast cancer.

  The New England journal of medicine 20061102

• Adjuvant chemotherapy for breast cancer--30 years later.

  The New England journal of medicine 20061102

• Nasal Wegener's and skin sarcoid--a rare combination of two granulomatous diseases.

  Clinical rheumatology 20061101

• An elderly female who survived more than 30 years following a diagnosis of Takayasu's arteritis, complicated by fatal intestinal amyloidosis.

  Clinical rheumatology 20061101

• Acute dermatomyositis with subcutaneous generalized edema.

  Clinical rheumatology 20061101

• Population pharmacokinetic study of methotrexate in patients with lymphoid malignancy.

  Cancer chemotherapy and pharmacology 20061101

• Comparing the long-term clinical outcome of treatment with methotrexate or sulfasalazine prescribed as the first disease-modifying antirheumatic drug in patients with inflammatory polyarthritis.

  Annals of the rheumatic diseases 20061101

• Protective effects of thymoquinone and methotrexate on the renal injury in collagen-induced arthritis.

  Archives of toxicology 20061101

• Recurrent gestational trophoblastic tumor: management and risk factors for recurrence.

  Gynecologic oncology 20061101

• [The significance of diet and associated factors in psoriasis].

  Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20061101

• Treatment and prognosis of post term choriocarcinoma in The Netherlands.

  Gynecologic oncology 20061101

• Alternatives to systemic steroid therapy for refractory immune-mediated inner ear disease: A physiopathologic approach.

  European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 20061101

• Copolymers of pharmaceutical grade lactic acid and sebacic acid: drug release behavior and biocompatibility.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20061101

• Prevention of oral lesions in children with acute lymphoblastic leukemia.

  International journal of pediatric otorhinolaryngology 20061101

• Effect of methotrexate treatment on expression levels of multidrug resistance protein 2, breast cancer resistance protein and organic anion transporters Oat1, Oat2 and Oat3 in rats.

  Cancer science 20061101

• The effect of 3435C>T MDR1 gene polymorphism on rheumatoid arthritis treatment with disease-modifying antirheumatic drugs.

  European journal of clinical pharmacology 20061101

• A new mechanism of methotrexate action revealed by target screening with affinity beads.

  Molecular pharmacology 20061101

• High leucovorin doses during high-dose methotrexate treatment may reduce the cure rate in childhood acute lymphoblastic leukemia.

  Leukemia 20061101

• Galactosylation of IgG from rheumatoid arthritis (RA) patients--changes during therapy.

  Glycoconjugate journal 20061101

• Gene expression profilers and conventional clinical markers to predict distant recurrences for premenopausal breast cancer patients after adjuvant chemotherapy.

  European journal of cancer (Oxford, England : 1990) 20061101

• Evaluation of methotrexate and corticosteroids for the treatment of localized scleroderma (morphoea) in children.

  The British journal of dermatology 20061101

• Treatment of Burkitt's lymphoma during pregnancy.

  The Annals of pharmacotherapy 20061101

• [Spondylarthritides].

  Zeitschrift fur Rheumatologie 20061101

• Similar efficacy for ovarian ablation compared with cyclophosphamide, methotrexate, and fluorouracil: from a randomized comparison of premenopausal patients with node-positive, hormone receptor-positive breast cancer.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20061101

• The DNA damage checkpoint is activated during residual tumour cell survival to methotrexate treatment as an initial step of acquired drug resistance.

  Anti-cancer drugs 20061101

• [A case of long-term survival of 3-years 4 months after combination chemotherapy of MTX, 5-FU and low-dose CDDP (MFP) for type 4 gastric cancer with pleuritis, peritoneal dissemination and Krukenberg tumor].

  Gan to kagaku ryoho. Cancer & chemotherapy 20061101

• High-dose methotrexate in pediatric acute lymphoblastic leukemia: impact of ABCC2 polymorphisms on plasma concentrations.

  Clinical pharmacology and therapeutics 20061101

• [A case of refractory Wegener's granulomatosis successfully treated with high-dose methotrexate].

  Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20061101

• [Neoadjuvant treatment in osteosarcomas].

  Bulletin du cancer 20061101

• Neurologic and morphologic features of dural ectasia in ankylosing spondylitis and rheumatoid arthritis: a case report.

  American journal of orthopedics (Belle Mead, N.J.) 20061101

• [MTX-CDDP-5-FU double modulation intra aortic chemotherapy for advanced and metastatic gastric cancer--a comparison with an intra venous route].

  Gan to kagaku ryoho. Cancer & chemotherapy 20061101

• Correlation between methotrexate efficacy & toxicity with C677T polymorphism of the methylenetetrahydrofolate gene in rheumatoid arthritis patients on folate supplementation.

  The Indian journal of medical research 20061101

• Encephalopathy in a patient after long-term treatment with thalidomide.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20061020

• Methotrexate for ankylosing spondylitis.

  The Cochrane database of systematic reviews 20061018

• [Churg-Strauss syndrome--recent developments in diagnosis and treatment].

  Deutsche medizinische Wochenschrift (1946) 20061013

• [Biologicals in the treatment of rheumatic diseases].

  Deutsche medizinische Wochenschrift (1946) 20061013

• Down regulation of multidrug resistance protein-1 expression in patients with early rheumatoid arthritis exposed to methotrexate as a first disease-modifying antirheumatic drug.

  Annals of the rheumatic diseases 20061001

• [Fulminant course of a Takayasu's arteritis and rare mesenteric arterial maninfestion].

  Zeitschrift fur Rheumatologie 20061001

• Methotrexate resistance in vitro is achieved by a dynamic selectionprocess of tumor cell variants emerging during treatment.

  International journal of cancer 20061001

• The activities of antioxidant enzymes and the level of malondialdehyde in cerebellum of rats subjected to methotrexate: protective effect of caffeic acid phenethyl ester.

  Molecular and cellular biochemistry 20061001

• Use of immortalized human hepatocytes to predict the magnitude of clinical drug-drug interactions caused by CYP3A4 induction.

  Drug metabolism and disposition: the biological fate of chemicals 20061001

• Sequential multidrug chemotherapy (CHOP-VA-MB) in patients with high-grade non-Hodgkin's lymphoma--a 20-year follow-up.

  Annals of hematology 20061001

• Successful father-to-son stem cell transplantation in a child with hemophagocytic lymphohistiocytosis using a reduced-intensity conditioning regimen.

  European journal of haematology 20061001

• Reduction of cardiovascular risk factors with longterm fish oil treatment in early rheumatoid arthritis.

  The Journal of rheumatology 20061001

• Results of CHOP chemotherapy for diffuse large B-cell lymphoma.

  Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20061001

• Evaluation of the prognostic and predictive value of p53 and Bcl-2 in breast cancer patients participating in a randomized study with dose-dense sequential adjuvant chemotherapy.

  Annals of oncology : official journal of the European Society for Medical Oncology 20061001

• Failed methotrexate termination of pregnancy: a case report.

  Journal of perinatology : official journal of the California Perinatal Association 20061001

• Pharmacogenomic and metabolic biomarkers in the folate pathway and their association with methotrexate effects during dosage escalation in rheumatoid arthritis.

  Arthritis and rheumatism 20061001

• Association of methotrexate effects and single-nucleotide polymorphisms in the folate pathway in rheumatoid arthritis: comment on the article by Wessels et al.

  Arthritis and rheumatism 20061001

• The use of methotrexate alone or in combination with low doses of oral corticosteroids in the treatment of alopecia totalis or universalis.

  Journal of the American Academy of Dermatology 20061001

• [Non-corticosteroid drug-induced metabolic bone disease].

  Presse medicale (Paris, France : 1983) 20061001

• A patient with breast cancer with hepatic metastases and a complete response to herceptin as monotherapy.

  Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20061001

• Primary treatment of metastatic high-risk gestational trophoblastic neoplasia with EMA-CO chemotherapy.

  The Journal of reproductive medicine 20061001

• Role of surgery in the management of high-risk gestational trophoblastic neoplasia.

  The Journal of reproductive medicine 20061001

• Management of gestational trophoblastic neoplasia with metastasis to the central nervous system: A 12-year review at the Philippine General Hospital.

  The Journal of reproductive medicine 20061001

• Management of postmolar gestational trophoblastic disease with methotrexate and folinic acid: 15 years of experience.

  The Journal of reproductive medicine 20061001

• Capecitabine/Cyclophosphamide/Methotrexate for patients with metastatic breast cancer: a dose-finding, feasibility, and efficacy study.

  Clinical breast cancer 20061001

• Investigation of the clinical effect of large volume leukocytapheresis on methotrexate-resistant rheumatoid arthritis.

  Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 20061001

• [Effect of adenovirus-mediated mutant exogenous P27kip1 gene expression on the chemosensitivities of cholangiocarcinoma cell line].

  Zhonghua wai ke za zhi [Chinese journal of surgery] 20061001

• [The clinical features of B cell lymphoblastic lymphoma and outcomes after BFM-90 regimen therapy].

  Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20061001

• Oral outpatient chemotherapy medication errors in children with acute lymphoblastic leukemia.

  Cancer 20060915

• Medical therapy: where are we now?

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20060915

• Oxidative stress induced by methotrexate alone and in the presence of methanol in discrete regions of the rodent brain, retina and optic nerve.

  Toxicology letters 20060910

• [Still's disease, adult-onset Still's disease (AOSD)].

  Praxis 20060906

• Racial or ethnic differences in allele frequencies of single-nucleotide polymorphisms in the methylenetetrahydrofolate reductase gene and their influence on response to methotrexate in rheumatoid arthritis.

  Annals of the rheumatic diseases 20060901

• [T-large granular lymphocyte leukaemia. An important differential diagnosis to Felty's syndrome].

  Zeitschrift fur Rheumatologie 20060901

• Metastatic choriocarcinoma successfully treated with paclitaxel and carboplatin after interstitial lung disease induced by EMA-CO.

  Gynecologic oncology 20060901

• Methotrexate induced differentiation in colon cancer cells is primarily due to purine deprivation.

  Journal of cellular biochemistry 20060901

• [Evolution and prognosis of adult onset Still's disease. A monocentric study of 17 patients].

  La Revue de medecine interne 20060901

• Fingerprinting DHFR in single-molecule AFM studies.

  Biophysical journal 20060901

• Interaction of valproic acid and carbapenem antibiotics with multidrug resistance-associated proteins in rat erythrocyte membranes.

  Epilepsy research 20060901

• Reduction in bioavailability of 6-mercaptopurine on simultaneous administration with cow's milk.

  Pediatric hematology and oncology 20060901

• Gelatin-methotrexate conjugate microspheres as a potential drug delivery system.

  Journal of pharmaceutical sciences 20060901

• MxA gene expression in juvenile dermatomyositis peripheral blood mononuclear cells: association with muscle involvement.

  Clinical immunology (Orlando, Fla.) 20060901

• Phase II study of unrelated cord blood transplantation for adults with high-risk hematologic malignancies.

  Bone marrow transplantation 20060901

• Providing medication abortion information to diverse communities: use patterns of a multilingual web site.

  Contraception 20060901

• Methotrexate pharmacogenomics.

  Annals of the rheumatic diseases 20060901

• HLA-G 14-bp polymorphism regulates the methotrexate response in rheumatoid arthritis.

  Pharmacogenetics and genomics 20060901

• Can dantrolene contribute to methotrexate toxicity?

  The Annals of pharmacotherapy 20060901

• Methotrexate therapy for the symptomatic treatment of primary biliary cirrhosis patients, who are biochemical incomplete responders to ursodeoxycholic acid therapy.

  Alimentary pharmacology & therapeutics 20060901

• The unmet treatment need for moderate to severe psoriasis: results of a survey and chart review.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20060901

• Confirmation and prevention of intestinal barrier dysfunction and bacterial translocation caused by methotrexate.

  Digestive diseases and sciences 20060901

• The effects of the anti-cancer drugs, methotrexate and 5-fluorouracil, on cognitive function in mice.

  Pharmacology, biochemistry, and behavior 20060901

• Determination of dissociation constants of folic acid, methotrexate, and other photolabile pteridines by pressure-assisted capillary electrophoresis.

  Electrophoresis 20060901

• Relationship between genetic variants in the adenosine pathway and outcome of methotrexate treatment in patients with recent-onset rheumatoid arthritis.

  Arthritis and rheumatism 20060901

• High-dose chemotherapy with autologous stem cell transplantation as first-line therapy for primary CNS lymphoma in patients younger than 60 years: a multicenter phase II study of the GOELAMS group.

  Bone marrow transplantation 20060901

• [Twenty years of treating childhood acute lymphoblastic leukemia].

  Anales de pediatria (Barcelona, Spain : 2003) 20060901

• Structure and reactivity of Trypanosoma brucei pteridine reductase: inhibition by the archetypal antifolate methotrexate.

  Molecular microbiology 20060901

• Methotrexate enhances the antianabolic and antiproliferative effects of 5-aminoimidazole-4-carboxamide riboside.

  Molecular cancer therapeutics 20060901

• Epstein-Barr virus associated Hodgkin lymphoma in a 9-year-old girl receiving long-term methotrexate therapy for juvenile idiopathic arthritis.

  Journal of pediatric hematology/oncology 20060901

• [Gemcitabine and cisplatin therapy in advanced or metastatic urothelial cancer: comparison of side effect with MVAC (methotrexate, vinblastine, doxorubicin, and cisplatin)].

  Nihon Hinyokika Gakkai zasshi. The japanese journal of urology 20060901

• [Gastropleural fistula due to perforated gastric ulcer].

  Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20060901

• [Second-line chemotherapy with gemcitabine and cisplatin for urothelial cancer previously treated with or resistant to M-VAC therapy].

  Hinyokika kiyo. Acta urologica Japonica 20060901

• [Bladder cancer with skin metastasis: a case report].

  Hinyokika kiyo. Acta urologica Japonica 20060901

• Treatment of Philadelphia-chromosome-positive acute lymphoblastic leukemia with imatinib in combination with chemotherapy.

  Current hematologic malignancy reports 20060901

• Methotrexate-albumin and aminopterin-albumin effectively prevent experimental acute graft-versus-host disease.

  Transplantation 20060827

• Methotrexate used in combination with aminolaevulinic acid for photodynamic killing of prostate cancer cells.

  British journal of cancer 20060821

• High-dose chemotherapy with autologous stem-cell transplantation and hyperfractionated radiotherapy as first-line treatment of primary CNS lymphoma.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060820

• Stable formation of mutated p53 multimers in a Chinese hamster cell line causes defective p53 nuclear localization and abrogates its residual function.

  Journal of cellular biochemistry 20060815

• Intrathecal triple therapy decreases central nervous system relapse but fails to improve event-free survival when compared with intrathecal methotrexate: results of the Children's Cancer Group (CCG) 1952 study for standard-risk acute lymphoblastic leukemia, reported by the Children's Oncology Group.

  Blood 20060815

• Antirheumatic drug use and the risk of acute myocardial infarction.

  Arthritis and rheumatism 20060815

• Conventional therapy for Crohn's disease.

  World journal of gastroenterology 20060814

• Gene expression and benefit of chemotherapy in women with node-negative, estrogen receptor-positive breast cancer.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060810

• Beta-glucan ameliorates methotrexate-induced oxidative organ injury via its antioxidant and immunomodulatory effects.

  European journal of pharmacology 20060807

• Chemotherapy versus ovarian ablation as adjuvant therapy for breast cancer: impact on health-related quality of life in a randomized trial.

  Breast cancer research and treatment 20060801

• Neoadjuvant treatment of gastric cancer with peritoneal dissemination.

  European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 20060801

• High-mannose-type glycan modifications of dihydrofolate reductase using glycan-methotrexate conjugates.

  Bioorganic & medicinal chemistry 20060801

• Four-way calibration applied to the simultaneous determination of folic acid and methotrexate in urine samples.

  Analytical and bioanalytical chemistry 20060801

• Interaction of methotrexate with organic-anion transporting polypeptide 1A2 and its genetic variants.

  The Journal of pharmacology and experimental therapeutics 20060801

• CMF versus goserelin as adjuvant therapy for node-negative, hormone-receptor-positive breast cancer in premenopausal patients: a randomised trial (GABG trial IV-A-93).

  European journal of cancer (Oxford, England : 1990) 20060801

• Adenosine A(2A) receptors play a role in the pathogenesis of hepatic cirrhosis.

  British journal of pharmacology 20060801

• T-cell large granular lymphocyte leukemia: A report on the treatment of 29 patients and a review of the literature.

  Cancer 20060801

• Epigenetic regulation of human gamma-glutamyl hydrolase activity in acute lymphoblastic leukemia cells.

  American journal of human genetics 20060801

• Folic acid supplementation and methotrexate therapy for psoriasis.

  Journal of the American Academy of Dermatology 20060801

• A proposed clinical test for monitoring fluoropyrimidine therapy: detection and stability of thymidylate synthase ternary complexes.

  Cancer biology & therapy 20060801

• Efficacy and safety of leflunomide alone and in combination with methotrexate in the treatment of refractory rheumatoid arthritis.

  Indian journal of medical sciences 20060801

• N-acetylcysteine ameliorates methotrexate-induced oxidative liver damage in rats.

  Medical science monitor : international medical journal of experimental and clinical research 20060801

• Methotrexate: improving safety profile.

  The Australasian journal of dermatology 20060801

• Folate cycle gene variants and chemotherapy toxicity in pediatric patients with acute lymphoblastic leukemia.

  Haematologica 20060801

• Temporal arteritis: report of a case.

  Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20060801

• Congenital localized scleroderma.

  The Journal of pediatrics 20060801

• Paclitaxel and epirubicin followed by cyclophosphamide, methotrexate and 5-fluorouracil for patients with stage IIIC breast cancer with ten or more involved axillary lymph nodes.

  American journal of clinical oncology 20060801

• Calpain inhibitors and antioxidants act synergistically to prevent cell necrosis: effects of the novel dual inhibitors (cysteine protease inhibitor and antioxidant) BN 82204 and its pro-drug BN 82270.

  Journal of neurochemistry 20060801

• Physical activity during treatment in children with leukemia: a pilot study.

  Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 20060801

• [Clinicopathological characteristics of gastric cancer in elderly patients].

  Gan to kagaku ryoho. Cancer & chemotherapy 20060801

• Fluorescein-methotrexate transport in dogfish shark (Squalus acanthias) choroid plexus.

  American journal of physiology. Regulatory, integrative and comparative physiology 20060801

• The molecular mechanism of resistance to methotrexate in mouse methotrexate-resistant cells by cancer drug resistance and metabolism SuperArray.

  Basic & clinical pharmacology & toxicology 20060801

• [Clinical study of unrelated umbilical cord blood transplantation in 32 children patients].

  Zhongguo shi yan xue ye xue za zhi 20060801

• Expression profiling of ATP-binding cassette transporters in childhood T-cell acute lymphoblastic leukemia.

  Molecular cancer therapeutics 20060801

• Squamous cell carcinoma of the bladder: a patient treated successfully with a new combined chemotherapy regimen, intraarterial nedaplatin and pirarubicin plus intravenous methotrexate and vincristine.

  International journal of clinical oncology 20060801

• [Treatment of malignant ovarian tumours in Georgia in 1990-2000].

  Georgian medical news 20060801

• [Double-mutant dihydrofolate reductase gene transfection into bone marrow cells protects mice from chemotherapy].

  Zhonghua zhong liu za zhi [Chinese journal of oncology] 20060801

• Methotrexate-induced encephaloclastic cyst: a complication of intraventricular chemotherapy.

  Neurology 20060725

• Immunosuppressive and cytotoxic therapy for pulmonary sarcoidosis.

  The Cochrane database of systematic reviews 20060719

• Combination chemotherapy for high-risk gestational trophoblastic tumour.

  The Cochrane database of systematic reviews 20060719

• Dose intensity of chemotherapy for osteosarcoma and outcome in the Cooperative Osteosarcoma Study Group (COSS) trials.

  Pediatric blood & cancer 20060701

• The incidence of Proteus mirabilis infection increases in patients on treatment but does not trigger disease activity.

  Clinical rheumatology 20060701

• Lack of efficacy of rituximab in Wegener's granulomatosis with refractory granulomatous manifestations.

  Annals of the rheumatic diseases 20060701

• Functional validation of the genetic polymorphisms of human ATP-binding cassette (ABC) transporter ABCG2: identification of alleles that are defective in porphyrin transport.

  Molecular pharmacology 20060701

• Carcinogen and anticancer drug transport by Mrp2 in vivo: studies using Mrp2 (Abcc2) knockout mice.

  The Journal of pharmacology and experimental therapeutics 20060701

• What is the best protocol of single-agent methotrexate chemotherapy in nonmetastatic or low-risk metastatic gestational trophoblastic tumors? A review of the evidence.

  Gynecologic oncology 20060701

• Methotrexate therapy for rheumatoid arthritis: clinical practice guidelines based on published evidence and expert opinion.

  Joint, bone, spine : revue du rhumatisme 20060701

• Cardiovascular risk and rheumatoid arthritis: clinical practice guidelines based on published evidence and expert opinion.

  Joint, bone, spine : revue du rhumatisme 20060701

• Methotrexate and ciclosporin combination for the treatment of severe psoriasis.

  Clinical and experimental dermatology 20060701

• Pharmacokinetic interaction between methotrexate and piperacillin/tazobactam resulting in prolonged toxic concentrations of methotrexate.

  The Journal of antimicrobial chemotherapy 20060701

• Conventional systemic agents for psoriasis. A systematic review.

  The Journal of rheumatology 20060701

• [A young woman with granulomatous mastitis: a corynebacteria may be involved in the pathogenesis of these disease].

  La Revue de medecine interne 20060701

• Cost-effectiveness analysis of MTHFR polymorphism screening by polymerase chain reaction in Korean patients with rheumatoid arthritis receiving methotrexate.

  The Journal of rheumatology 20060701

• How should best strategy and tight control be translated into clinical practice? Comment on the article by Goekoop-Ruiterman et al.

  Arthritis and rheumatism 20060701

• Formulas calculating creatinine clearance are inadequate for determining eligibility for Cisplatin-based chemotherapy in bladder cancer.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060701

• [Treatment of systemic sclerosis].

  Zeitschrift fur Rheumatologie 20060701

• Dietary caffeine intake does not affect methotrexate efficacy in patients with rheumatoid arthritis.

  The Journal of rheumatology 20060701

• Anti-tumor necrosis factor-alpha-induced psoriasis.

  The Journal of rheumatology 20060701

• Computer-aided detection of therapy-induced leukoencephalopathy in pediatric acute lymphoblastic leukemia patients treated with intravenous high-dose methotrexate.

  Magnetic resonance imaging 20060701

• Multifocal necrotizing leukoencephalopathy: An unusual complication of acute leukemia.

  Archives of neurology 20060701

• Determinants of the elimination of methotrexate and 7-hydroxy-methotrexate following high-dose infusional therapy to cancer patients.

  British journal of clinical pharmacology 20060701

• Giant cell arteritis--the methotrexate debate revisited.

  The Journal of rheumatology 20060701

• Low-dose cyclosporin A with short-term methotrexate for graft-versus-host disease prophylaxis in allogeneic bone marrow transplantation from human leukocyte antigen-identical siblings: a prospective phase II study in Japanese patients.

  International journal of hematology 20060701

• First-line ifosfamide, methotrexate, etoposide and prednisolone chemotherapy +/- radiotherapy is active in stage I/II extranodal NK/T-cell lymphoma.

  Leukemia & lymphoma 20060701

• Methotrexate-induced renal oxidative stress in rats: the role of a novel antioxidant caffeic acid phenethyl ester.

  Toxicology and industrial health 20060701

• [Acute lymphoblastic leukaemia in Danish children and young people 10 to 19 years of age. Should young adults with acute lymphoblastic leukaemia be treated in the same way as children?].

  Ugeskrift for laeger 20060626

• Computer modelling of antifolate inhibition of folate metabolism using hybrid functional petri nets.

  Journal of theoretical biology 20060621

• Pharmacogenetics in inflammatory bowel disease.

  World journal of gastroenterology 20060621

• Central nervous system recurrence in adult patients with acute lymphoblastic leukemia: frequency and prognosis in 467 patients without cranial irradiation for prophylaxis.

  Cancer 20060615

• Alteration of the Fc gamma RIIa dimer interface affects receptor signaling but not ligand binding.

  Journal of immunology (Baltimore, Md. : 1950) 20060615

• Chemically controlled self-assembly of protein nanorings.

  Journal of the American Chemical Society 20060614

• Chemotherapy options for patients with metastatic or recurrent squamous cell carcinoma of the head and neck.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060610

• Pharmacodynamic properties of methotrexate and Aminotrexate during weekly therapy.

  Cancer chemotherapy and pharmacology 20060601

• Classic disease modifying anti-rheumatic drugs (DMARDs) in combination with infliximab. The Finnish experience.

  Rheumatology international 20060601

• Takayasu's arteritis associated with antiphospholipid antibodies.

  Rheumatology international 20060601

• Anti-inflammatory effects of leflunomide in combination with methotrexate on co-culture of T lymphocytes and synovial macrophages from rheumatoid arthritis patients.

  Annals of the rheumatic diseases 20060601

• Erythrocyte concentrations of metabolites or cumulative doses of 6-mercaptopurine and methotrexate do not predict liver changes in children treated for acute lymphoblastic leukemia.

  Pediatric blood & cancer 20060601

• A new strategy of high-speed screening and quantitative structure-activity relationship analysis to evaluate human ATP-binding cassette transporter ABCG2-drug interactions.

  The Journal of pharmacology and experimental therapeutics 20060601

• In vitro and in vivo prodrug therapy of prostate cancer using anti-gamma-Sm-scFv/hCPA fusion protein.

  The Prostate 20060601

• Outcome of treatment in adults with Philadelphia chromosome-positive and/or BCR-ABL--positive acute lymphoblastic leukemia-retrospective analysis of Polish Adult Leukemia Group (PALG).

  Annals of hematology 20060601

• Effect of aged garlic extract against methotrexate-induced damage to the small intestine in rats.

  Phytotherapy research : PTR 20060601

• Interstitial pneumonitis associated with infliximab therapy.

  The Journal of rheumatology 20060601

• A randomized phase III comparative trial of immediate consolidation with high-dose chemotherapy and autologous peripheral blood progenitor cell support compared to observation with delayed consolidation in women with metastatic breast cancer and only bone metastases following intensive induction chemotherapy.

  Bone marrow transplantation 20060601

• In regards to Arcangeli et al. (Int J Radiat Oncol Biol Phys 2006;64:161-167).

  International journal of radiation oncology, biology, physics 20060601

• Diagnosis of liver fibrosis by transient elastography (FibroScan) and non-invasive methods in Crohn's disease patients treated with methotrexate.

  Alimentary pharmacology & therapeutics 20060601

• Medial tibial stress syndrome due to methotrexate osteopathy.

  Annals of the rheumatic diseases 20060601

• Leflunomide and methotrexate combination therapy in daily clinical practice.

  Annals of the rheumatic diseases 20060601

• TS-1 as first-line therapy for gastric linitis plastica: historical control study.

  Anti-cancer drugs 20060601

• Folic acid supplementation during treatment of psoriasis with methotrexate: a randomized, double-blind, placebo-controlled trial.

  The British journal of dermatology 20060601

• Remission of a primary thyroid lymphoma after methotrexate withdrawal.

  Clinical endocrinology 20060601

• In juvenile idiopathic arthritis, is folate supplementation effective against methotrexate toxicity at the expense of methotrexate's efficacy?

  Archives of disease in childhood 20060601

• Lupus anticoagulant and ischemic myocardial microangiopathy in rheumatoid arthritis.

  Nature clinical practice. Cardiovascular medicine 20060601

• Allogeneic marrow transplantation in patients with severe systemic sclerosis: resolution of dermal fibrosis.

  Arthritis and rheumatism 20060601

• Therapy of childhood generalized morphea: case reports and reviews of the literature of Japanese cases.

  Pediatrics international : official journal of the Japan Pediatric Society 20060601

• Primary extranodal nasal-type natural killer/T-cell lymphoma of the brain: a case report.

  Human pathology 20060601

• Granulomatous uveitis revealing Wegener's granulomatosis.

  The Journal of rheumatology 20060601

• Dermatitis herpetiformis and rheumatoid arthritis.

  Saudi medical journal 20060601

• Diagnosis of a primary testicular lymphoma by echography and magnetic resonance imaging.

  Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20060601

• Understanding and managing methotrexate nephrotoxicity.

  The oncologist 20060601

• Growth-inhibitory action of melatonin and thiazolidinedione derivative CGP 52608 on murine 16/C breast cancer cells.

  Neuro endocrinology letters 20060601

• [An abdominal Burkitt's lymphoma in acute phase. Case report].

  Minerva pediatrica 20060601

• Effects of anti-TNF-alpha treatment on lipid profile in patients with active rheumatoid arthritis.

  Annals of the New York Academy of Sciences 20060601

• Bone metabolism changes during anti-TNF-alpha therapy in patients with active rheumatoid arthritis.

  Annals of the New York Academy of Sciences 20060601

• Treating itch in psoriasis.

  Dermatology nursing 20060601

• Structure and function of the MRP2 (ABCC2) protein and its role in drug disposition.

  Expert opinion on drug metabolism & toxicology 20060601

• Chronic plaque psoriasis.

  Clinical evidence 20060601

• [Case of leptomeningeal carcinomatosis effectively treated with intrathecal chemotherapy using ventriculoperitoneal shunt].

  Rinsho shinkeigaku = Clinical neurology 20060601

• [Non surgical management of ectopic pregnancy].

  La Tunisie medicale 20060601

• Methotrexate-immobilized poly(ethylene glycol) magnetic nanoparticles for MR imaging and drug delivery.

  Small (Weinheim an der Bergstrasse, Germany) 20060601

• Primary endobronchial anaplastic large cell lymphoma in a pediatric patient.

  Puerto Rico health sciences journal 20060601

• Study of failure pattern among high-risk breast cancer patients with or without postmastectomy radiotherapy in addition to adjuvant systemic therapy: long-term results from the Danish Breast Cancer Cooperative Group DBCG 82 b and c randomized studies.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060520

• Effect of tamoxifen after chemotherapy in hormone receptor-positive, node-negative breast cancer.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060520

• HER2 and responsiveness of breast cancer to adjuvant chemotherapy.

  The New England journal of medicine 20060518

• Folate synthesis in plants: purification, kinetic properties, and inhibition of aminodeoxychorismate synthase.

  The Biochemical journal 20060515

• MATILDE regimen followed by radiotherapy is an active strategy against primary CNS lymphomas.

  Neurology 20060509

• Randomised trial: survival benefit and safety of adjuvant dose-dense chemotherapy for node-positive breast cancer.

  British journal of cancer 20060508

• Methotrexate induces cell swelling and necrosis in renal tubular cells.

  Pediatric blood & cancer 20060501

• Lethal acute respiratory distress syndrome during anti-TNF-alpha therapy for rheumatoid arthritis.

  Clinical rheumatology 20060501

• Magnetic resonance imaging in the differential diagnosis between polymyalgia rheumatica and elderly onset rheumatoid arthritis.

  Clinical rheumatology 20060501

• Synthesis of oligotuftsin-based branched oligopeptide conjugates for chemotactic drug targeting.

  Journal of peptide science : an official publication of the European Peptide Society 20060501

• Osmotic blood-brain barrier disruption chemotherapy for diffuse pontine gliomas.

  Journal of neuro-oncology 20060501

• Methotrexate is a new selectable marker for tobacco immature pollen transformation.

  Plant cell reports 20060501

• Dose-dense adjuvant chemotherapy for node-positive breast cancer in women 60 years and older: feasibility and tolerability in a subset of patients in a randomized trial.

  Critical reviews in oncology/hematology 20060501

• Gene expression and angiotropism in primary CNS lymphoma.

  Blood 20060501

• MTHFR 677 (C-->T) polymorphism is not relevant for prognosis or therapy-associated toxicity in pediatric NHL: results from 484 patients of multicenter trial NHL-BFM 95.

  Annals of hematology 20060501

• Rituximab as therapy for refractory polymyositis and dermatomyositis.

  The Journal of rheumatology 20060501

• Sequential chemotherapy with cisplatin/gemcitabine (CG) followed by mitoxantrone/methotrexate/mitomycin (MMM) in patients with malignant pleural mesothelioma. A multicenter Italian Phase II Study (SITMP1).

  Lung cancer (Amsterdam, Netherlands) 20060501

• Reduced-intensity allogeneic haemopoietic stem cell transplantation induces durable responses in patients with chronic B-lymphoproliferative disorders.

  Bone marrow transplantation 20060501

• Application of intrathecal trastuzumab (Herceptintrade mark) for treatment of meningeal carcinomatosis in HER2-overexpressing metastatic breast cancer.

  Oncology reports 20060501

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Density and structural changes in the bone of growing rats after weekly alendronate administration with and without a methotrexate challenge.

  Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20060501

• Bosentan may induce arthritis flare in patients with scleroderma concomitantly treated with methotrexate.

  Annals of the rheumatic diseases 20060501

• The significance of minimal residual disease kinetics in adults with newly diagnosed PML-RARalpha-positive acute promyelocytic leukemia: results of a prospective trial.

  Haematologica 20060501

• Keratoacanthoma centrifugum marginatum: response to topical 5-fluorouracil.

  Journal of the American Academy of Dermatology 20060501

• A pediatric case of nephrogenic fibrosing dermopathy: improvement after combination therapy.

  Journal of the American Academy of Dermatology 20060501

• Occurrence and impact of unanticipated variation in intravenous methotrexate dosing.

  The Annals of pharmacotherapy 20060501

• [Pelvic Burkitt lymphoma mimicking an ovarian tumor].

  Journal de gynecologie, obstetrique et biologie de la reproduction 20060501

• Combination treatment with methotrexate, cyclosporine, and intraarticular betamethasone compared with methotrexate and intraarticular betamethasone in early active rheumatoid arthritis: an investigator-initiated, multicenter, randomized, double-blind, parallel-group, placebo-controlled study.

  Arthritis and rheumatism 20060501

• Effect of folic acid supplementation on the efficacy of methotrexate treatment in rheumatoid arthritis: comment on the article by Khanna et al.

  Arthritis and rheumatism 20060501

• Effects of topical application of methotrexate on nasal mucosa in rats: a preclinical assessment study.

  Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20060501

• Methotrexate, bleomycin, and Etoposide in the treatment of gestational trophoblastic neoplasia.

  Obstetrics and gynecology 20060501

• The efficacy and safety of rituximab in patients with active rheumatoid arthritis despite methotrexate treatment: results of a phase IIB randomized, double-blind, placebo-controlled, dose-ranging trial.

  Arthritis and rheumatism 20060501

• Controlled trial of methotrexate versus CH-1504 in the treatment of rheumatoid arthritis.

  The Journal of rheumatology 20060501

• Safety of infliximab used in combination with leflunomide or azathioprine in daily clinical practice.

  The Journal of rheumatology 20060501

• Angry fat.

  The Journal of rheumatology 20060501

• Use of amino terminal type III procollagen peptide (P3NP) assay in methotrexate therapy for psoriasis.

  Postgraduate medical journal 20060501

• Treatment of vulval Crohn's disease with infliximab.

  Clinical and experimental dermatology 20060501

• [Establishment of a multidrug-resistant cell line BEL-7402/5-FU of human hepatocellular carcinoma and its biological characteristics].

  Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20060501

• Polyneuropathy, organomegaly, endocrinopathy, M protein, skin changes: not always a POEMS syndrome.

  Haematologica 20060501

• Evaluation of an ex vivo model implication for carrier-mediated retinal drug delivery.

  Current eye research 20060501

• [Neurological complications during and after the treatment of acute lymphocytic leukemia].

  No to hattatsu = Brain and development 20060501

• Proteomic analysis for the identification of proteins related to methotrexate resistance.

  Yi chuan xue bao = Acta genetica Sinica 20060501

• [Infliximab-induced hepatitis in a patient with Crohn's disease].

  Gastroenterologia y hepatologia 20060501

• [Bladder preservation for locally advanced bladder cancer by transurethral resection, systemic chemotherapy and radiation].

  Hinyokika kiyo. Acta urologica Japonica 20060501

• Clearance of methotrexate by means of hemofiltration in a patient with osteosarcoma.

  Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20060501

• [Acute diarrhea in a patient with rheumatoid arthritis].

  Enfermedades infecciosas y microbiologia clinica 20060501

• Gemcitabine in the treatment of advanced transitional cell carcinoma of the urothelium.

  Annals of oncology : official journal of the European Society for Medical Oncology 20060501

• Long-term survival results of a randomized trial comparing gemcitabine/cisplatin and methotrexate/vinblastine/doxorubicin/cisplatin in patients with locally advanced and metastatic bladder cancer.

  Annals of oncology : official journal of the European Society for Medical Oncology 20060501

• Unilateral generalized morphea is a rare variant of localized scleroderma.

  European journal of medical research 20060428

• Intraocular injection of folate antagonist methotrexate induces neuronal differentiation of embryonic stem cells transplanted in the adult mouse retina.

  Brain research 20060426

• Knockdown of hypoxia-inducible factor-1alpha in breast carcinoma MCF-7 cells results in reduced tumor growth and increased sensitivity to methotrexate.

  Biochemical and biophysical research communications 20060421

• Coexistence of multiple mechanisms of PT523 resistance in human leukemia cells harboring 3 reduced folate carrier alleles: transcriptional silencing, inactivating mutations, and allele loss.

  Blood 20060415

• Colony-stimulating factor-1 antibody reverses chemoresistance in human MCF-7 breast cancer xenografts.

  Cancer research 20060415

• The impact on health-related quality of life from non-steroidal anti-inflammatory drugs, methotrexate, or steroids in treatment for juvenile idiopathic arthritis.

  Journal of pediatric psychology 20060401

• An open label, single dose study to evaluate the safety, efficacy, and effects on CD25 expression of ciclosporin in patients with active rheumatoid arthritis despite treatment with methotrexate and infliximab.

  Annals of the rheumatic diseases 20060401

• Twelve years experience of juvenile dermatomyositis in North India.

  Rheumatology international 20060401

• Gene expression profiling of 30 cancer cell lines predicts resistance towards 11 anticancer drugs at clinically achieved concentrations.

  International journal of cancer 20060401

• Methotrexate modulates the kinetics of adenosine in humans in vivo.

  Annals of the rheumatic diseases 20060401

• Kinetic validation of the use of carboxydichlorofluorescein as a drug surrogate for MRP5-mediated transport.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20060401

• The role of dose size in a chemotherapy regimen (ProMECE-CytaBOM) for the first-line treatment of large B-cell lymphomas: a randomized trial by the Gruppo Italiano Studio Linfomi (GISL).

  Annals of oncology : official journal of the European Society for Medical Oncology 20060401

• Pretreatment plasma folate modulates the pharmacodynamic effect of high-dose methotrexate in children with acute lymphoblastic leukemia and non-Hodgkin lymphoma: 'folate overrescue' concept revisited.

  Clinical chemistry 20060401

• Evaluation of chemotherapy with magnetic resonance imaging in patients with regionally metastatic or unresectable bladder cancer.

  European urology 20060401

• Prognostic index score and clinical prediction model of local regional recurrence after mastectomy in breast cancer patients.

  International journal of radiation oncology, biology, physics 20060401

• Folic acid supplementation during methotrexate immunosuppression is not associated with early toxicity, risk of acute graft-versus-host disease or relapse following hematopoietic transplantation.

  Bone marrow transplantation 20060401

• The conservative management of cervical ectopic pregnancies.

  Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 20060401

• Donor methylenetetrahydrofolate reductase genotype is associated with graft-versus-host disease in hematopoietic stem cell transplant patients treated with methotrexate.

  Bone marrow transplantation 20060401

• Going with the flow: methotrexate, adenosine, and blood flow.

  Annals of the rheumatic diseases 20060401

• Role of treatment intensification in infants with acute lymphoblastic leukemia: results of two consecutive AIEOP studies.

  Haematologica 20060401

• Eosinophilic pustular folliculitis induced by chemotherapy.

  Journal of the American Academy of Dermatology 20060401

• Naso-maxillary non-Hodgkin lymphoma associated with methotrexate treatment in a patient with rheumatoid arthritis.

  Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 20060401

• Methotrexate reduces the complications of endophthalmitis resulting from intravitreal injection compared with dexamethasone in a rabbit model.

  Investigative ophthalmology & visual science 20060401

• Comparison of etanercept and methotrexate, alone and combined, in the treatment of rheumatoid arthritis: two-year clinical and radiographic results from the TEMPO study, a double-blind, randomized trial.

  Arthritis and rheumatism 20060401

• Efficacy and toxicity of methotrexate in early rheumatoid arthritis are associated with single-nucleotide polymorphisms in genes coding for folate pathway enzymes.

  Arthritis and rheumatism 20060401

• Initial combo therapy best way to treat RA. Study shows MTX plus prednisone or the biologic infliximab may stop RA in its tracks.

  Health news (Waltham, Mass.) 20060401

• In vivo analysis of Drosophila deoxyribonucleoside kinase function in cell cycle, cell survival and anti-cancer drugs resistance.

  Cell cycle (Georgetown, Tex.) 20060401

• 5-amino-4-imidazolecarboxamide riboside potentiates both transport of reduced folates and antifolates by the human reduced folate carrier and their subsequent metabolism.

  Cancer research 20060401

• Management of pediatric Vogt-Koyanagi- Harada (VKH)-associated panuveitis.

  Ocular immunology and inflammation 20060401

• A case of breast carcinoma late metastasis to the kidney.

  American journal of clinical oncology 20060401

• Concurrent chemoradiotherapy with cisplatin, 5-fluorouracil, methotrexate, and leucovorin in patients with advanced resectable squamous cell carcinoma of the larynx and hypopharynx.

  Acta oto-laryngologica 20060401

• ZNRD1 mediates resistance of gastric cancer cells to methotrexate by regulation of IMPDH2 and Bcl-2.

  Biochemistry and cell biology = Biochimie et biologie cellulaire 20060401

• [Primary central nervous system lymphoma--a report of 32 cases with literature review].

  Ai zheng = Aizheng = Chinese journal of cancer 20060401

• Revisiting the immunomodulators tacrolimus, methotrexate, and mycophenolate mofetil: their mechanisms of action and role in the treatment of IBD.

  Inflammatory bowel diseases 20060401

• A medical management of interstitial ectopic pregnancy: a 5-year clinical study.

  The Australian & New Zealand journal of obstetrics & gynaecology 20060401

• Persistent trophoblast disease following partial molar pregnancy.

  The Australian & New Zealand journal of obstetrics & gynaecology 20060401

• [IEMAD (modified MIME) therapy for refractory or relapsed non-Hodgkin's lymphoma].

  Zhongguo shi yan xue ye xue za zhi 20060401

• Psoriasis treatment in the United States at the end of the 20th century.

  International journal of dermatology 20060401

• A case of protein-losing enteropathy treated with methotrexate in a dog.

  The Journal of veterinary medical science 20060401

• A 19-year-old male with generalized seizures, unconsciousness and a deviation of gaze.

  Brain pathology (Zurich, Switzerland) 20060401

• [Sarcoidosis and granulomatous disease: observation].

  Revue des maladies respiratoires 20060401

• Electrostatic evaluation of isosteric analogues.

  Journal of computer-aided molecular design 20060401

• Early rheumatoid arthritis: combination therapy with disease-modifying antirheumatic drugs and low-dose glucocorticoids?

  Nature clinical practice. Rheumatology 20060401

• Effect of glutamate receptor antagonists and antirheumatic drugs on proliferation of synoviocytes in vitro.

  European journal of pharmacology 20060327

• Cyclin D1 antisense oligodexoyneucleotides inhibits growth and enhances chemosensitivity in gastric carcinoma cells.

  World journal of gastroenterology 20060321

• Supratentorial primitive neuroectodermal tumors (S-PNET) in children: A prospective experience with adjuvant intensive chemotherapy and hyperfractionated accelerated radiotherapy.

  International journal of radiation oncology, biology, physics 20060315

• Cause-specific mortality in long-term survivors of breast cancer: A 25-year follow-up study.

  International journal of radiation oncology, biology, physics 20060315

• Patient reported outcomes in a trial of combination therapy with etanercept and methotrexate for rheumatoid arthritis: the TEMPO trial.

  Annals of the rheumatic diseases 20060301

• Pulmonary involvement in lifelong non-smoking patients with rheumatoid arthritis and ankylosing spondylitis without respiratory symptoms.

  Clinical rheumatology 20060301

• Benefits of low weekly doses of methotrexate in steroid-dependent asthmatic patients. A double-blind, randomized, placebo-controlled study.

  Respiratory medicine 20060301

• Cutaneous lymphocytic vasculitis during TNFalpha antagonist therapy for polyarthritis.

  Joint, bone, spine : revue du rhumatisme 20060301

• Clinical results and quality of life analysis for the MVAC combination (methotrexate, vinblastine, doxorubicin, and cisplatin) in carcinoma of the uterine cervix: A Gynecologic Oncology Group study.

  Gynecologic oncology 20060301

• Whole brain magnetization transfer histogram analysis of pediatric acute lymphoblastic leukemia patients receiving intrathecal methotrexate therapy.

  European journal of radiology 20060301

• Long-term follow-up of a randomised trial designed to determine the need for irradiation following conservative surgery for the treatment of invasive breast cancer.

  Annals of oncology : official journal of the European Society for Medical Oncology 20060301

• Disease-modifying anti-rheumatic drugs are only one of a number of potential causes of myelosuppression: a careful drug history is necessary to elucidate the cause of an adverse event.

  Rheumatology (Oxford, England) 20060301

• Reversible acute methotrexate leukoencephalopathy: atypical brain MR imaging features.

  Pediatric radiology 20060301

• Linear quadratic modeling of increased late normal-tissue effects in special clinical situations.

  International journal of radiation oncology, biology, physics 20060301

• Emerging therapies in juvenile rheumatoid/idiopathic arthritis.

  Current problems in pediatric and adolescent health care 20060301

• Continued survival of more than ten years, without resection of metastatic disease, in patients with metastatic colorectal cancer treated with biomodulated fluorouracil: report of two cases.

  Diseases of the colon and rectum 20060301

• Incidence, time course, and determinants of menstrual bleeding after breast cancer treatment: a prospective study.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060301

• Catalase activity in Candida albicans exposed to antineoplastic drugs.

  Journal of medical microbiology 20060301

• Plasmodium vivax dihydrofolate reductase as a target of sulpha drugs.

  FEMS microbiology letters 20060301

• The treatment of psoriasis and psoriatic arthritis: an interdisciplinary approach.

  Journal of the American Academy of Dermatology 20060301

• Roles of protein C, protein S, and antithrombin III in acute leukemia.

  American journal of hematology 20060301

• Methotrexate for treatment of primary biliary cirrhosis.

  Hepatology (Baltimore, Md.) 20060301

• Reflections on therapeutic trials in primary biliary cirrhosis: a quality of life oriented counter-view.

  Hepatology (Baltimore, Md.) 20060301

• Ultraviolet recall phenomenon associated with methotrexate and cytarabine.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20060301

• Results of the Brazilian Osteosarcoma Treatment Group Studies III and IV: prognostic factors and impact on survival.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060301

• Increasing ornithine decarboxylase activity is another way of prolactin preventing methotrexate-induced apoptosis: crosstalk between ODC and BCL-2.

  Apoptosis : an international journal on programmed cell death 20060301

• American Gastroenterological Association Institute medical position statement on corticosteroids, immunomodulators, and infliximab in inflammatory bowel disease.

  Gastroenterology 20060301

• American Gastroenterological Association Institute technical review on corticosteroids, immunomodulators, and infliximab in inflammatory bowel disease.

  Gastroenterology 20060301

• [Adjuvant chemotherapy based on evidence-based medicine for breast cancer patients].

  Gan to kagaku ryoho. Cancer & chemotherapy 20060301

• [A case of recurrent breast cancer with life-threatening multiple lung metastasis markedly responding to CMF as third-line chemotherapy].

  Gan to kagaku ryoho. Cancer & chemotherapy 20060301

• Treatment of ankylosing spondylitis with medicated moxibustion plus salicylazosulfapyridine and methotrexate--a report of 30 cases.

  Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 20060301

• The effect of thalidomide on corticosteroid-dependent pulmonary sarcoidosis.

  Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG 20060301

• Diagnosis and management of spinal cord sarcoidosis.

  Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG 20060301

• Therapeutic response to single intravenous bolus administration of formate dehydrogenase in methanol-intoxicated rats.

  Toxicology letters 20060220

• Overcoming methotrexate resistance in breast cancer tumour cells by the use of a new cell-penetrating peptide.

  Biochemical pharmacology 20060214

• Dual inhibitors of thymidylate synthase and dihydrofolate reductase as antitumor agents: design, synthesis, and biological evaluation of classical and nonclassical pyrrolo[2,3-d]pyrimidine antifolates(1).

  Journal of medicinal chemistry 20060209

• Alpha-tocopheryl succinate alters cell cycle distribution sensitising human osteosarcoma cells to methotrexate-induced apoptosis.

  Cancer letters 20060208

• Growth inhibition, drug load, and degradation studies of gelatin/methotrexate conjugates.

  International journal of pharmaceutics 20060203

• De novo and salvage pathways of DNA synthesis in primary cultured neurall stem cells.

  Brain research 20060203

• Prolonged remission in adult-onset Still's disease with etanercept.

  Clinical rheumatology 20060201

• The effects of methotrexate on Drosophila development, female fecundity, and gene expression.

  Toxicological sciences : an official journal of the Society of Toxicology 20060201

• Randomized phase III trials of adjuvant FAMTX or FEMTX compared with surgery alone in resected gastric cancer. A combined analysis of the EORTC GI Group and the ICCG.

  Annals of oncology : official journal of the European Society for Medical Oncology 20060201

• Metronomic low-dose oral cyclophosphamide and methotrexate plus or minus thalidomide in metastatic breast cancer: antitumor activity and biological effects.

  Annals of oncology : official journal of the European Society for Medical Oncology 20060201

• The activity of adenosine deaminase and the level of nitric oxide in spinal cord of methotrexate administered rats: protective effect of caffeic acid phenethyl ester.

  Toxicology 20060201

• Gonadotropin-releasing hormone analogues added to adjuvant chemotherapy protect ovarian function and improve clinical outcomes in young women with early breast carcinoma.

  Cancer 20060201

• Predictors of immunomodulator use as early therapy in pediatric Crohn's disease.

  Journal of clinical gastroenterology 20060201

• Eosinophilic fasciitis in a child mimicking a myopathy.

  Neuromuscular disorders : NMD 20060201

• A case of pseudolymphomatous folliculitis.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20060201

• Etanercept monotherapy for a patient with psoriasis, psoriatic arthritis, and concomitant hepatitis C infection.

  Journal of the American Academy of Dermatology 20060201

• Risk genotypes in folate-dependent enzymes and their association with methotrexate-related side effects in rheumatoid arthritis.

  Arthritis and rheumatism 20060201

• Treatment for rheumatoid arthritis and the risk of hospitalization for pneumonia: associations with prednisone, disease-modifying antirheumatic drugs, and anti-tumor necrosis factor therapy.

  Arthritis and rheumatism 20060201

• I've taken methotrexate for several months to control my rheumatoid arthritis, but the bouts of upset stomach have become too much. I read that folic acid can counteract the side effects of methotrexate. Can you tell me more about it?

  Health news (Waltham, Mass.) 20060201

• Effects of methylenetetrahydrofolate reductase and reduced folate carrier 1 polymorphisms on high-dose methotrexate-induced toxicities in children with acute lymphoblastic leukemia or lymphoma.

  Journal of pediatric hematology/oncology 20060201

• Treatment of severe disseminated juvenile systemic xanthogranuloma with multiple lesions in the central nervous system.

  Journal of pediatric hematology/oncology 20060201

• bcr-abl-positive T-cell acute lymphoblastic leukemia associated with parvovirus B19 infection.

  Journal of pediatric hematology/oncology 20060201

• Meningeal involvement in Wegener's granulomatosis.

  The Journal of rheumatology 20060201

• The schedule-dependent effects of the novel antifolate pralatrexate and gemcitabine are superior to methotrexate and cytarabine in models of human non-Hodgkin's lymphoma.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20060201

• A case of methotrexate embryopathy with holoprosencephaly, expanding the phenotype.

  Birth defects research. Part A, Clinical and molecular teratology 20060201

• Predictors of success of repeated injections of single-dose methotrexate regimen for tubal ectopic pregnancy.

  Journal of Korean medical science 20060201

• Preparation and in vitro and in vivo evaluation of technetium-99m-labeled folate and methotrexate conjugates as tumor imaging agents.

  Cancer biotherapy & radiopharmaceuticals 20060201

• [Recent progress in the treatment for urothelial cancer].

  Gan to kagaku ryoho. Cancer & chemotherapy 20060201

• The inverse relationship between reduced folate carrier function and pemetrexed activity in a human colon cancer cell line.

  Molecular cancer therapeutics 20060201

• [Wegener's granulomatosis: Pathogenesis, pathophysiology, and therapy].

  Nihon rinsho. Japanese journal of clinical medicine 20060201

• Concurrent radiotherapy does not affect adjuvant CMF delivery but is associated with increased toxicity in women with early breast cancer.

  Journal of chemotherapy (Florence, Italy) 20060201

• Treatment of psoriatic arthritis with etanercept, methotrexate, and cyclosporin A.

  Clinical therapeutics 20060201

• Acute lymphoblastic leukemia in adolescents between 10 and 19 years of age in Denmark--secondary publication.

  Danish medical bulletin 20060201

• Prodrug forms of N-[(4-deoxy-4-amino-10-methyl)pteroyl]glutamate-gamma-[psiP(O)(OH)]-glutarate, a potent inhibitor of folylpoly-gamma-glutamate synthetase: synthesis and hydrolytic stability.

  Journal of medicinal chemistry 20060126

• [Survival prospects of mesopharyngeal carcinoma patients treated primarily with intraarterial chemotherapy. A retrospective study].

  Orvosi hetilap 20060122

• Metastatic osteosarcoma.

  Cancer 20060115

• Drosophila dihydrofolate reductase mutations confer antifolate resistance to mammalian cells.

  European journal of pharmacology 20060104

• Influence of serum folic acid levels on plasma homocysteine concentrations in patients with rheumatoid arthritis.

  Rheumatology international 20060101

• The impact of plasma protein binding on the renal transport of organic anions.

  The Journal of pharmacology and experimental therapeutics 20060101

• A phase III randomized study on the sequencing of radiotherapy and chemotherapy in the conservative management of early-stage breast cancer.

  International journal of radiation oncology, biology, physics 20060101

• Favorable outcome of primary mediastinal large B-cell lymphoma in a single institution: the British Columbia experience.

  Annals of oncology : official journal of the European Society for Medical Oncology 20060101

• A successful case of allogeneic bone marrow transplantation for osteosarcoma with multiple metastases of lung and bone.

  Bone marrow transplantation 20060101

• Decreased risk of acute gastrointestinal toxicity when substituting methotrexate with mycophenolate mofetil in the prevention of graft-versus-host disease in stem cell transplantation following myeloablative conditioning regimens.

  Bone marrow transplantation 20060101

• Influence of methotrexate, TNF blockers and prednisolone on antibody responses to pneumococcal polysaccharide vaccine in patients with rheumatoid arthritis.

  Rheumatology (Oxford, England) 20060101

• Use of the 13C-sucrose breath test to assess chemotherapy-induced small intestinal mucositis in the rat.

  Cancer biology & therapy 20060101

• Precipitation of generalized pustular psoriasis by prednisolone.

  Clinical and experimental dermatology 20060101

• High-dose methotrexate-associated acute renal failure may be an avoidable complication.

  Pediatric hematology and oncology 20060101

• Complete long-term survival data from a trial of adjuvant chemotherapy vs control after radical cystectomy for locally advanced bladder cancer.

  BJU international 20060101

• Advances in the therapy of Wegener's granulomatosis.

  Current opinion in rheumatology 20060101

• Adalimumab clinical efficacy is associated with rheumatoid factor and anti-cyclic citrullinated peptide antibody titer reduction: a one-year prospective study.

  Arthritis research & therapy 20060101

• Combining infliximab with methotrexate for the induction and maintenance of remission in refractory Crohn's disease: a controlled pilot study.

  European journal of gastroenterology & hepatology 20060101

• Granulocytic sarcoma of the gingiva with trisomy 21.

  American journal of hematology 20060101

• From methotrexate to pemetrexed and beyond. A review of the pharmacodynamic and clinical properties of antifolates.

  Investigational new drugs 20060101

• Early identification of resistance to first-line single-agent methotrexate in patients with persistent trophoblastic disease.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060101

• Nutritional supplementation with transforming growth factor-beta, glutamine, and short chain fatty acids minimizes methotrexate-induced injury.

  Journal of pediatric gastroenterology and nutrition 20060101

• Choriocarcinoma with markedly elevated serum hCG levels and negative urine hCG levels.

  Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 20060101

• Itraconazole-enhanced chemotherapy toxicity in a patient with Hodgkin lymphoma.

  Journal of pediatric hematology/oncology 20060101

• Neoadjuvant interstitial high-dose-rate (HDR) brachytherapy combined with systemic chemotherapy in patients with breast cancer.

  Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] 20060101

• Reduced-intensity conditioning followed by unrelated umbilical cord blood transplantation for advanced hematologic malignancies: rapid engraftment in bone marrow.

  International journal of hematology 20060101

• [Thermo-chemo-radiotherapy for advanced biliary carcinoma].

  Nihon rinsho. Japanese journal of clinical medicine 20060101

• L-Carnitine ameliorates methotrexate-induced oxidative organ injury and inhibits leukocyte death.

  Cell biology and toxicology 20060101

• Burkitt's lymphoma presenting as oculomotor palsy in an hiv-positive patient.

  European journal of ophthalmology 20060101

• Methotrexate in rheumatoid arthritis is frequently effective, even if re-employed after a previous failure.

  Arthritis research & therapy 20060101

• Breast-conserving therapy after neoadjuvant chemotherapy: long-term results.

  The breast journal 20060101

• Radiation recall dermatitis after the use of the anorexiant phentermine in a patient with breast cancer.

  The breast journal 20060101

• Diagnosis and management of male breast cancer in the community hospital setting.

  The breast journal 20060101

• Successful pregnancy after localized resection of perforated uterus in choriocarcinoma and a literature review.

  International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20060101

• Suppression of inflammation by low-dose methotrexate is mediated by adenosine A2A receptor but not A3 receptor activation in thioglycollate-induced peritonitis.

  Arthritis research & therapy 20060101

• Long-term treatment of Hashimoto's encephalopathy.

  The Journal of neuropsychiatry and clinical neurosciences 20060101

• Pancytopenia after low dose methotrexate therapy in a hemodialysis patient: case report and review of literature.

  Renal failure 20060101

• Activity of dendrimer-methotrexate conjugates on methotrexate-sensitive and -resistant cell lines.

  Bioconjugate chemistry 20060101

• Antibodies against transglutaminases, peptidylarginine deiminase and citrulline in rheumatoid arthritis--new pathways to epitope spreading.

  Clinical and experimental rheumatology 20060101

• Acute and long-term neurologic complications in children with acute lymphoblastic leukemia.

  The Turkish journal of pediatrics 20060101

• Infliximab is effective for Takayasu arteritis refractory to glucocorticoid and methotrexate.

  Internal medicine (Tokyo, Japan) 20060101

• Genomic alterations identified by array comparative genomic hybridization as prognostic markers in tamoxifen-treated estrogen receptor-positive breast cancer.

  BMC cancer 20060101

• Quality of life is improved in breast cancer patients by Standardised Mistletoe Extract PS76A2 during chemotherapy and follow-up: a randomised, placebo-controlled, double-blind, multicentre clinical trial.

  Anticancer research 20060101

• CMF with 5-FU in continuous infusion--a pilot study.

  European journal of gynaecological oncology 20060101

• Efficacy and safety of bucillamine, a D-penicillamine analogue, in patients with active rheumatoid arthritis.

  Modern rheumatology 20060101

• [A comparison between the Simplified Disease Activity Index (SDAI) and the Disease Activity Score (DAS28) as measure of response to treatment in patients undergoing different therapeutic regimens].

  Reumatismo 20060101

• [Side effects of anti-TNFalpha therapy in juvenile idiopathic arthritis].

  Reumatismo 20060101

• [Case report: RAEB in a patient with rheumatoid arthritis treated with methotrexate and infliximab].

  Reumatismo 20060101

• Atherogenic lipid profile is a feature characteristic of patients with early rheumatoid arthritis: effect of early treatment--a prospective, controlled study.

  Arthritis research & therapy 20060101

• Progressive sclerodermatous skin changes in a child with phenylketonuria.

  Pediatric dermatology 20060101

• Clinical and immunological effects of Rituximab in patients with lupus nephritis refractory to conventional therapy: a pilot study.

  Arthritis research & therapy 20060101

• Evolution of treatment of high-risk metastatic gestational trophoblastic tumors: Ain Shams University experience.

  International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20060101

• Gestational trophoblastic tumor in pregnancy: a case report and review of the literature.

  International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20060101

• The role of hysterotomy in the management of gestational trophoblastic neoplasia.

  International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20060101

• Bacillary angiomatosis following the use of long-term methotrexate therapy: a case report.

  The West Virginia medical journal 20060101

• Uterine choriocarcinoma in a postmenopausal woman.

  Medical oncology (Northwood, London, England) 20060101

• Suppression of circulating interleukin-6 concentrations is associated with decreased endothelial activation in rheumatoid arthritis.

  Clinical and experimental rheumatology 20060101

• Combination therapy with acitretin for psoriasis.

  The Journal of dermatological treatment 20060101

• Results with EMA/CO (etoposide, methotrexate, actinomycin D, cyclophosphamide, vincristine) chemotherapy in gestational trophoblastic neoplasia.

  International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20060101

• Gene profiling in white blood cells predicts infliximab responsiveness in rheumatoid arthritis.

  Arthritis research & therapy 20060101

• Oxaliplatin combined with 5-fluorouracil and methotrexate in advanced colorectal cancer.

  Anticancer research 20060101

• Raloxifene attenuation of 5-FU/methotrexate cytotoxicity in human breast cancer cells: the importance of sequence in combination chemotherapy.

  Anticancer research 20060101

• Raloxifene attenuation of methotrexate cytotoxicity in human bone marrow by sequence-dependent administration of raloxifene, 5-FU/methotrexate.

  Anticancer research 20060101

• Expression of the high-affinity fluoropyrimidine-preferring nucleoside transporter hCNT1 correlates with decreased disease-free survival in breast cancer.

  Oncology 20060101

• Folliculotropic mycosis fungoides with follicular mucinosis--case report.

  Acta dermatovenerologica Croatica : ADC 20060101

• Predictors of infusion reactions during infliximab treatment in patients with arthritis.

  Arthritis research & therapy 20060101

• Treatment continuation rate in relation to efficacy and toxicity in long-term therapy with low-dose methotrexate, sulfasalazine, and bucillamine in 1,358 Japanese patients with rheumatoid arthritis.

  Clinical and experimental rheumatology 20060101

• Myocarditis in adult-onset Still's disease despite significant immunosuppressive therapy.

  Scandinavian journal of rheumatology 20060101

• [Acute lymphoblastic leukemia in children with initial leucocytosis above 50,000/mm3: summary of treatment results of Polish Pediatric Leukemia/Lymphoma Study Group].

  Przeglad lekarski 20060101

• Acceptability and usefulness of mizoribine in the management of rheumatoid arthritis in methotrexate-refractory patients and elderly patients, based on analysis of data from a large-scale observational cohort study.

  Modern rheumatology 20060101

• Infectious myositis involving the piriformis in a patient with rheumatoid arthritis.

  Modern rheumatology 20060101

• Disseminated invasive aspergillosis in a patient with acute leukaemia.

  Acta bio-medica : Atenei Parmensis 20060101

• Radiation-induced leiomyosarcoma of the oropharynx.

  Diagnostic pathology 20060101

• Pharmacokinetic considerations in the treatment of CNS tumours.

  Clinical pharmacokinetics 20060101

• Tolerability and safety of classic cyclophosphamide, methotrexate, and fluorouracil treatment in Japanese patients with early breast cancer.

  Breast cancer (Tokyo, Japan) 20060101

• Nitric oxide levels in patients with psoriasis treated with methotrexate.

  Mediators of inflammation 20060101

• A phase II study of combined chemotherapy with methotrexate, 5-fluorouracil, and low-dose cisplatin (MFP) for histologically diffuse-type advanced and recurrent gastric cancer (KDOG9501).

  Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 20060101

• Penicillin-induced anti-p200 pemphigoid: an unusual morphology.

  Acta dermato-venereologica 20060101

• Etanercept in the treatment of arthritis in a patient with familial Mediterranean fever.

  Clinical and experimental rheumatology 20060101

• Effect of triptolide on expression of receptor activator of nuclear factor-kappaB ligand in rat adjuvant induced arthritis.

  Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20060101

• Methotrexate in rheumatoid arthritis.

  Pharmacological reports : PR 20060101

• Four-year follow-up of infliximab therapy in rheumatoid arthritis patients with long-standing refractory disease: attrition and long-term evolution of disease activity.

  Arthritis research & therapy 20060101

• Trastuzumab in combination with metronomic cyclophosphamide and methotrexate in patients with HER-2 positive metastatic breast cancer.

  BMC cancer 20060101

• Disease-modifying antirheumatic drugs are associated with a reduced risk for cardiovascular disease in patients with rheumatoid arthritis: a case control study.

  Arthritis research & therapy 20060101

• Design of a new line in treatment of experimental rheumatoid arthritis by artesunate.

  Immunopharmacology and immunotoxicology 20060101

• [Are there any positive effects of TNF-alpha blockers on bone metabolism?].

  Reumatismo 20060101

• [Ultrasonographic assessment of the response to Etanercept treatment in patients with rheumatoid arthritis].

  Reumatismo 20060101

• An Asian patient with intraocular lymphoma treated by intravitreal methotrexate.

  Japanese journal of ophthalmology 20060101

• A novel assay for monitoring internalization of nanocarrier coupled antibodies.

  BMC immunology 20060101

• Evaluation of Pneumocystis pneumonia infection risk factors in patients with connective tissue disease.

  Modern rheumatology 20060101

• [Adaptation of methotrexate determination in plasma with Dimension Xpand].

  Annales de biologie clinique 20060101

• Methotrexate loaded solid lipid nanoparticles (SLN) for effective treatment of carcinoma.

  Journal of nanoscience and nanotechnology 20060101

• Approaches to discontinuing efalizumab: an open-label study of therapies for managing inflammatory recurrence.

  BMC dermatology 20060101

• Acute ascending motoric paraplegia following intrathecal chemotherapy for treatment of acute lymphoblastic leukemia in children: case reports and review of the literature.

  Klinische Padiatrie 20060101

• Remission as the treatment goal--the FIN-RACo trial.

  Clinical and experimental rheumatology 20060101

• Aiming at low disease activity in rheumatoid arthritis with initial combination therapy or initial monotherapy strategies: the BeSt study.

  Clinical and experimental rheumatology 20060101

• A treatment strategy for psoriasis: transitioning from systemic therapy to biologic agents.

  Skinmed 20060101

• [Bladder preservation possibilities in the treatment of muscle-invasive bladder cancer].

  Medicina (Kaunas, Lithuania) 20060101

• Adverse events from systemic therapies for psoriasis are common in clinical practice.

  The Journal of dermatological treatment 20060101

• Methotrexate enhances the anti-inflammatory effect of CF101 via up-regulation of the A3 adenosine receptor expression.

  Arthritis research & therapy 20060101

• Population pharmacokinetics of high-dose methotrexate in children with acute lymphoblastic leukaemia.

  Clinical pharmacokinetics 20060101

• Impact of concomitant DMARD therapy on adherence to treatment with etanercept and infliximab in rheumatoid arthritis. Results from a six-year observational study in southern Sweden.

  Arthritis research & therapy 20060101

• Examination of the rescue effects of folic acid on derangement of the tubo-ovarian ultrastructural architecture caused by methotrexate.

  Advances in therapy 20060101

• Resolution of activity (choroiditis and choroidal neovascularization) of chronic recurrent punctate inner choroidopathy after treatment with interferon B-1A.

  Retina (Philadelphia, Pa.) 20060101

• Recommendations for the use of methotrexate in juvenile idiopathic arthritis.

  Paediatric drugs 20060101

• Methotrexate and hepatic toxicity in rheumatoid arthritis and psoriatic arthritis.

  Clinical drug investigation 20060101

• Nuclear receptor interactions in methotrexate induction of human dehydroepiandrosterone sulfotransferase (hSULT2A1).

  Journal of biochemical and molecular toxicology 20060101

• The effect of methotrexate on bone metabolism markers in patients with rheumatoid arthritis.

  Modern rheumatology 20060101

• Efficacy profile of bucillamine in rheumatoid arthritis patients in a large observational cohort study, IORRA.

  Modern rheumatology 20060101

• Polymyositis associated with infliximab treatment for rheumatoid arthritis.

  Modern rheumatology 20060101

• [Detection of external contamination of methotrexate vials in an Argentine hospital].

  Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20060101

• The effects of anticancer drugs on levels of nitric oxide and adrenomedullin.

  The Turkish journal of pediatrics 20060101

• Bullous variant of acral erythema due to methotrexate.

  Indian journal of dermatology, venereology and leprology 20060101

• Cyclosporine A in juvenile idiopathic arthritis. Results of the PRCSG/PRINTO phase IV post marketing surveillance study.

  Clinical and experimental rheumatology 20060101

• Development of type 1 diabetes mellitus in a patient with rheumatoid arthritis receiving anti-tumor necrosis factor alpha.

  Clinical and experimental rheumatology 20060101

• Visual field changes in methotrexate therapy. Case report and review of the literature.

  Le Journal medical libanais. The Lebanese medical journal 20060101

• In vitro studies of the properties of thermosensitive systems prepared on Pluronic F-127 as vehicles for methotrexate for delivery to solid tumours.

  Polimery w medycynie 20060101

• Association of tumour necrosis factor a, b and c microsatellite polymorphisms with clinical disease activity and induction of remission in early rheumatoid arthritis.

  Clinical and experimental rheumatology 20060101

• Aortic valve calcification in systemic lupus erythematosus.

  Lupus 20060101

• [Modern strategy of diagnostics and management of patients with rheumatoid arthritis].

  Polskie Archiwum Medycyny Wewnetrznej 20060101

• [Therapeutic maintenance level of methotrexate in rheumatoid arthritis].

  Sante (Montrouge, France) 20060101

• Autoimmune hemolytic anemia as presenting manifestation of primary splenic anaplastic large cell lymphoma.

  The Turkish journal of pediatrics 20060101

• [Reults of treatment with protocols BFM 90 and BFM 95].

  Medicinski arhiv 20060101

• Adjuvant dose-dense sequential chemotherapy with epirubicin, CMF, and weekly docetaxel is feasible and safe in patients with operable breast cancer.

  Medical oncology (Northwood, London, England) 20060101

• Second line chemotherapy with methotrexate and gemcitabine in patients with relapsing head and neck cancer.

  Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20060101

• Treatment of childhood psoriasis.

  Acta dermatovenerologica Croatica : ADC 20060101

• 99mTc-MIBI scintigraphy as a functional method for the evaluation of multidrug resistance in breast cancer patients.

  Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20060101

• [Auditory evoked potentials in patients after acute children's lymphoblastic leukemia treatment].

  Przeglad lekarski 20060101

• [Rational therapeutic approach in rheumatoid arthritis].

  Annales Academiae Medicae Stetinensis 20060101

• [Cyclosporine combined with another basic drug for the management of rheumatoid arthritis].

  Annales Academiae Medicae Stetinensis 20060101

• [Coincidence of juvenile idiopathic arthritis and multiple sclerosis: case report].

  Annales Academiae Medicae Stetinensis 20060101

• The added therapeutic efficacy and safety of alefacept in combination with other (systemic) anti-psoriatics in refractory psoriasis.

  The Journal of dermatological treatment 20060101

• Unspoken vowel recognition using facial electromyogram.

  Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference 20060101

• Persistent clinical response of infliximab therapy in patients with refractory rheumatoid arthritis, over a 3-year period.

  Current clinical pharmacology 20060101

• Therapy of moderate and severe psoriasis.

  GMS health technology assessment 20060101

• Involvement of C3435T and G2677T multidrug resistance gene polymorphisms in release of cytokines from peripheral blood mononuclear cells treated with methotrexate and dexamethasone.

  European journal of pharmacology 20051228

• Early rheumatoid arthritis treatments weighed.

  JAMA 20051228

• Primary biliary cirrhosis.

  The New England journal of medicine 20051222

• Feasibility and tolerability of sequential doxorubicin/paclitaxel followed by cyclophosphamide, methotrexate, and fluorouracil and its effects on tumor response as preoperative therapy.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20051215

• [Armentarium and strategies for the treatment of rheumatoid arthritis].

  La Revue du praticien 20051215

• Targeted drug delivery with dendrimers: comparison of the release kinetics of covalently conjugated drug and non-covalent drug inclusion complex.

  Advanced drug delivery reviews 20051214

• MRI and conservative treatment of locally advanced breast cancer.

  European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 20051201

• Micronucleated erythrocyte frequencies in old and new world primates: measurement of micronucleated erythrocyte frequencies in peripheral blood of Callithrix jacchus as a model for evaluating genotoxicity in primates.

  Environmental and molecular mutagenesis 20051201

• Quantitative structure-activity relationships of methotrexate and methotrexate analogues transported by the rat multispecific resistance-associated protein 2 (rMrp2).

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20051201

• Cellular accumulation of tetrahydrobiopterin following its administration is mediated by two different processes; direct uptake and indirect uptake mediated by a methotrexate-sensitive process.

  Molecular genetics and metabolism 20051201

• Neoadjuvant chemotherapy with high-dose Ifosfamide, high-dose methotrexate, cisplatin, and doxorubicin for patients with localized osteosarcoma of the extremity: a joint study by the Italian and Scandinavian Sarcoma Groups.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20051201

• Successful management of sudden, massive immune hemolysis following ABO-incompatible allogeneic PBSCT despite methotrexate GvHD prophylaxis.

  Bone marrow transplantation 20051201

• Delivery of exogenous tetrahydrobiopterin (BH4) to cells of target organs: role of salvage pathway and uptake of its precursor in effective elevation of tissue BH4.

  Molecular genetics and metabolism 20051201

• IMVP-16/Pd followed by high-dose chemotherapy and autologous stem cell transplantation as a salvage therapy for refractory or relapsed peripheral T-cell lymphomas.

  Leukemia & lymphoma 20051201

• Thymidylate synthase pharmacogenetics.

  Investigational new drugs 20051201

• Burkitt lymphoma in adults: a prospective study of 72 patients treated with an adapted pediatric LMB protocol.

  Annals of oncology : official journal of the European Society for Medical Oncology 20051201

• Relationship between 5,10-methylenetetrahydrofolate reductase C677T gene polymorphism and methotrexate related toxicity in patients with autoimmune diseases receiving folic acid supplementation.

  Annals of the rheumatic diseases 20051201

• Adjuvant chemotherapy for Merkel cell carcinoma.

  American journal of clinical oncology 20051201

• Cell-cycle-dependent pharmacology of methotrexate in HL-60.

  Journal of pharmacological sciences 20051201

• Controlled growth of Chinese hamster ovary cells and high expression of antibody-IL-2 fusion proteins by temperature manipulation.

  Biotechnology letters 20051201

• A phase 2 dose-finding study of PEGylated recombinant methionyl human soluble tumor necrosis factor type I in patients with rheumatoid arthritis.

  The Journal of rheumatology 20051201

• Disseminated cutaneous infection with Mycobacterium chelonae mimicking panniculitis in a patient with dermatomyositis.

  Hong Kong medical journal = Xianggang yi xue za zhi 20051201

• p16 inactivation associated with aggressive clinical course and fatal outcome in TEL/AML1-positive acute lymphoblastic leukemia.

  Journal of pediatric hematology/oncology 20051201

• [Clinical analysis of 67 patients with brain metastases from breast cancer].

  Ai zheng = Aizheng = Chinese journal of cancer 20051201

• [Attempts to improve organ preservation in patients with squamous cell carcinoma of the head and neck].

  Gan to kagaku ryoho. Cancer & chemotherapy 20051201

• [A randomized crossover study of ramosetron plus dexamethasone for the prevention of nausea and vomiting induced by chemotherapy including cisplatin-comparison of ramosetron combined with 8 mg and 12 mg of dexamethasone].

  Gan to kagaku ryoho. Cancer & chemotherapy 20051201

• [Improved quality of life in a patient with carcinomatous meningitis from invasive lobular carcinoma treated with intrathecal MTX and Ara-C in combination with systemic docetaxel].

  Gan to kagaku ryoho. Cancer & chemotherapy 20051201

• Combination chemotherapy with adriamycin, cyclophosphamide, vincristine, methotrexate, etoposide and dexamethasone (ACOMED) followed by involved field radiotherapy induces high remission rates and durable long-term survival in patients with aggressive malignant non-Hodgkin's lymphomas: long-term follow-up of a pilot study.

  Leukemia & lymphoma 20051201

• What is new in the therapy of ANCA-associated vasculitides? Take home messages from the 12th workshop on ANCA and systemic vasculitides.

  Clinical nephrology 20051201

• Effect of oral colestimide on the elimination of high-dose methotrexate in patients with primary central nervous system lymphoma--case report.

  Neurologia medico-chirurgica 20051201

• Primary central nervous system lymphoma in a renal transplant recipient with Bardet-Biedl syndrome.

  Transplantation proceedings 20051201

• [Analysis on symptomatic factors of rheumatoid arthritis and its correlation with therapeutic efficacy].

  Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20051201

• What news in urological cancer.

  La Tunisie medicale 20051201

• Ophthalmic zoster sine herpete presenting as oculomotor palsy after marrow transplantation for acute myeloid leukemia.

  Haematologica 20051201

• Pharmacogenetics of therapies in rheumatoid arthritis.

  Drugs of today (Barcelona, Spain : 1998) 20051201

• Multiple cutaneous and uterine leiomyomas associated with gastric GIST.

  Journal of cutaneous medicine and surgery 20051201

• New treatment options have changed the survival of patients with follicular lymphoma.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20051120

• Randomized, controlled trial of cyclophosphamide, methotrexate, and fluorouracil versus cyclophosphamide, doxorubicin, and fluorouracil with and without tamoxifen for high-risk, node-negative breast cancer: treatment results of Intergroup Protocol INT-0102.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20051120

• Higher plant plastids and cyanobacteria have folate carriers related to those of trypanosomatids.

  The Journal of biological chemistry 20051118

• Synthesis of N-{4-[(2,4-diamino-5-methyl-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)thio]benzoyl}-L-glutamic acid and N-{4-[(2-amino-4-oxo-5-methyl-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)thio]benzoyl}-L-glutamic acid as dual inhibitors of dihydrofolate reductase and thymidylate synthase and as potential antitumor agents.

  Journal of medicinal chemistry 20051117

• Taurine protects against methotrexate-induced toxicity and inhibits leukocyte death.

  Toxicology and applied pharmacology 20051115

• Anaplastic large cell lymphoma treated with a leukemia-like therapy: report of the Italian Association of Pediatric Hematology and Oncology (AIEOP) LNH-92 protocol.

  Cancer 20051115

• Determination of methotrexate, several pteridines, and creatinine in human urine, previous oxidation with potassium permanganate, using HPLC with photometric and fluorimetric serial detection.

  Analytical biochemistry 20051115

• Potential mechanisms for chemotherapy-induced impairments in cognitive function.

  Oncology nursing forum 20051103

• Selection strategies for the establishment of recombinant Chinese hamster ovary cell line with dihydrofolate reductase-mediated gene amplification.

  Applied microbiology and biotechnology 20051101

• Light chain multiple myeloma in a patient with long-standing rheumatoid arthritis.

  Clinical rheumatology 20051101

• Comparison of different definitions to classify remission and sustained remission: 1 year TEMPO results.

  Annals of the rheumatic diseases 20051101

• Diabetes insipidus presentation before renal and pulmonary features in a patient with Wegener's granulomatosis.

  Rheumatology international 20051101

• Low-dose methotrexate treatment for oligoarticular juvenile idiopathic arthritis nonresponsive to intra-articular corticosteroids.

  Clinical rheumatology 20051101

• Relapse of primary CNS lymphoma after more than 10 years in complete remission.

  Journal of neurology 20051101

• The changing use of disease-modifying anti-rheumatic drugs in individuals with rheumatoid arthritis from the United Kingdom General Practice Research Database.

  Rheumatology (Oxford, England) 20051101

• Primary lacrimal sac non-Hodgkin's lymphoma in a child.

  International journal of pediatric otorhinolaryngology 20051101

• Ligand binding modulates the mechanical stability of dihydrofolate reductase.

  Biophysical journal 20051101

• Patients' preferences for adjuvant chemotherapy in early breast cancer: what makes AC and CMF worthwhile now?

  Annals of oncology : official journal of the European Society for Medical Oncology 20051101

• Human multidrug resistance associated protein 4 confers resistance to camptothecins.

  Pharmaceutical research 20051101

• Postoperative dose-dense sequential chemotherapy with epirubicin, followed by CMF with or without paclitaxel, in patients with high-risk operable breast cancer: a randomized phase III study conducted by the Hellenic Cooperative Oncology Group.

  Annals of oncology : official journal of the European Society for Medical Oncology 20051101

• Toxoplasma gondii is capable of exogenous folate transport. A likely expansion of the BT1 family of transmembrane proteins.

  Molecular and biochemical parasitology 20051101

• Safety and efficacy of leflunomide and infliximab versus methotrexate and infliximab combination therapy in rheumatoid arthritis.

  Rheumatology (Oxford, England) 20051101

• Electrophysiological correlates of information processing in breast-cancer patients treated with adjuvant chemotherapy.

  Breast cancer research and treatment 20051101

• Methotrexate prevents renal injury in experimental diabetic rats via anti-inflammatory actions.

  Journal of the American Society of Nephrology : JASN 20051101

• The potential of pharmacogenetics in optimizing the use of methotrexate for psoriasis.

  The British journal of dermatology 20051101

• Methotrexate (MTX) plus ursodeoxycholic acid (UDCA) in the treatment of primary biliary cirrhosis.

  Hepatology (Baltimore, Md.) 20051101

• Reflections on therapeutic trials in primary biliary cirrhosis.

  Hepatology (Baltimore, Md.) 20051101

• The effectiveness of treating juvenile dermatomyositis with methotrexate and aggressively tapered corticosteroids.

  Arthritis and rheumatism 20051101

• Selection of adjuvant chemotherapy for treatment of node-positive breast cancer.

  The Lancet. Oncology 20051101

• Tamoxifen versus control after adjuvant, risk-adapted chemotherapy in postmenopausal, receptor-negative patients with breast cancer: a randomized trial (GABG-IV D-93)--the German Adjuvant Breast Cancer Group.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20051101

• Long-term outcome in children with relapsed ALL by risk-stratified salvage therapy: results of trial acute lymphoblastic leukemia-relapse study of the Berlin-Frankfurt-Münster Group 87.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20051101

• Involvement of P-glycoprotein in the release of cytokines from peripheral blood mononuclear cells treated with methotrexate and dexamethasone.

  The Journal of pharmacy and pharmacology 20051101

• Staphylococcus aureus in patients with rheumatoid arthritis under conventional and anti-tumor necrosis factor-alpha treatment.

  The Journal of rheumatology 20051101

• Skin cancer, rheumatoid arthritis, and tumor necrosis factor inhibitors.

  The Journal of rheumatology 20051101

• Membranous glomerulopathy in children given allogeneic hematopoietic stem cell transplantation.

  Haematologica 20051101

• Manipulation of membrane protein topology on the endoplasmic reticulum by a specific ligand in living cells.

  Journal of biochemistry 20051101

• [Correlations of clinical symptoms and treatment efficacy in patients with rheumatoid arthritis treated with Chinese herbal drugs or Western medicine].

  Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20051101

• [SNPs associated with adverse effects].

  Gan to kagaku ryoho. Cancer & chemotherapy 20051101

• Intracranial plasma cell granuloma: case report and treatment of recurrence with methotrexate and 6-mercaptopurine.

  Journal of pediatric hematology/oncology 20051101

• Fas expression in lung metastasis from osteosarcoma patients.

  Journal of pediatric hematology/oncology 20051101

• Panaortitis: diagnosis via fluorodeoxyglucose positron emission tomography.

  The American journal of the medical sciences 20051101

• Acute pseudobulbar palsy due to methotrexate with rapid response to intravenous immunoglobulin.

  Journal of neurology 20051101

• [Adverse events in rheumatoid arthritis patient with etanercept therapy: the appearance of osteomalacia].

  Recenti progressi in medicina 20051101

• retrospective analysis of topoisomerase IIa amplifications and deletions as predictive markers in primary breast cancer patients randomly assigned to cyclophosphamide, methotrexate, and fluorouracil or cyclophosphamide, epirubicin, and fluorouracil: Danish Breast Cancer Cooperative Group.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20051020

• Treatment with all-trans retinoic acid and anthracycline monochemotherapy for children with acute promyelocytic leukemia: a multicenter study by the PETHEMA Group.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20051020

• Genetic determinants of methotrexate responsiveness and resistance in colon cancer cells.

  Oncogene 20051013

• [Crohn's disease--standards of treatment 2004].

  Praxis 20051012

• Diagnosis and treatment of ectopic pregnancy.

  CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20051011

• Medical treatment of juvenile idiopathic arthritis.

  JAMA 20051005

• The inhibitory effect of disease-modifying anti-rheumatic drugs and steroids on gliostatin/platelet-derived endothelial cell growth factor production in human fibroblast-like synoviocytes.

  Rheumatology international 20051001

• Liposome-mediated transfection of mature taste cells.

  Journal of neurobiology 20051001

• The curative effect of a second curettage in persistent trophoblastic disease: a retrospective cohort survey.

  Gynecologic oncology 20051001

• Stereoselectivity of the reduced folate carrier in Caco-2 cells.

  Chirality 20051001

• Human organic anion transporter hOAT3 is a potent transporter of cephalosporin antibiotics, in comparison with hOAT1.

  Biochemical pharmacology 20051001

• Environmental contamination with cytotoxic drugs in healthcare using positive air pressure isolators.

  The Annals of occupational hygiene 20051001

• Ultrastructural changes in rat livers perfused in vitro and in vivo with a high dose of methotrexate.

  Histology and histopathology 20051001

• The pharmacogenetics of methotrexate in inflammatory bowel disease.

  Pharmacogenetics and genomics 20051001

• Low-dose oral methotrexate for maintaining Crohn's disease remission: where we stand.

  Journal of clinical gastroenterology 20051001

• Evaluation of toxicities induced by chemotherapy in breast cancer patients.

  Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20051001

• Crystal structure of Trypanosoma cruzi pteridine reductase 2 in complex with a substrate and an inhibitor.

  Journal of structural biology 20051001

• Coadministration of lansoprazole and naproxen does not affect the pharmacokinetic profile of methotrexate in adult patients with rheumatoid arthritis.

  Journal of clinical pharmacology 20051001

• The impact of age and gender on biology, clinical features and treatment outcome of non-Hodgkin lymphoma in childhood and adolescence.

  British journal of haematology 20051001

• Nasal ulcers in the ED: from Wegener's granulomatosis.

  The American journal of emergency medicine 20051001

• Steroid-responsive (autoimmune?) sclerosing cholangitis.

  Digestive diseases and sciences 20051001

• Prognostic value of extracapsular tumor spread for locoregional control in premenopausal patients with node-positive breast cancer treated with classical cyclophosphamide, methotrexate, and fluorouracil: long-term observations from International Breast Cancer Study Group Trial VI.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20051001

• Central nervous system chemoprophylaxis in non-Hodgkin lymphoma: current practice in the UK.

  British journal of haematology 20051001

• Folate supplementation during methotrexate therapy for patients with psoriasis.

  Journal of the American Academy of Dermatology 20051001

• Benefits of axillary radiotherapy unclear in women with early stage breast cancer undergoing conservative breast surgery without axillary dissection.

  Cancer treatment reviews 20051001

• Reduction of the efficacy of methotrexate by the use of folic acid: post hoc analysis from two randomized controlled studies.

  Arthritis and rheumatism 20051001

• Langerhans cell histiocytosis of the atlas. A report of three cases.

  The Journal of bone and joint surgery. American volume 20051001

• Pharmacogenetics of folate-related drug targets in cancer treatment.

  Pharmacogenomics 20051001

• A quantitative MR imaging assessment of leukoencephalopathy in children treated for acute lymphoblastic leukemia without irradiation.

  AJNR. American journal of neuroradiology 20051001

• [Treatment strategy for primary gastric cancer with peritoneal dissemination].

  Gan to kagaku ryoho. Cancer & chemotherapy 20051001

• [Case report--postoperative continuous intraarterial infusion of small doses of 5-FU successfully controlled residual tumor and liver metastasis of stage IV gastric cancer].

  Gan to kagaku ryoho. Cancer & chemotherapy 20051001

• Is low-dose methotrexate nephrotoxic? Case report and review of the literature.

  Clinical nephrology 20051001

• Brain white matter changes during treatment of a child for acute lymphoblastic leukemia.

  Journal of Nippon Medical School = Nippon Ika Daigaku zasshi 20051001

• Pemphigus vulgaris: a case-based update.

  Journal (Canadian Dental Association) 20051001

• [Delayed improvement of anemia treated with intravenous iron and epoetin alfa after hip replacement surgery].

  Revista espanola de anestesiologia y reanimacion 20051001

• Term delivery choriocarcinoma patient with brain and lung metastases successfully treated by etoposide, methotrexate, actomycin D, cyclophosphamide and vincristine (EMA-CO) chemotherapy.

  Acta medica Okayama 20051001

• Wegener's granulomatosis: a challenging disease for otorhinolaryngologists.

  Acta oto-laryngologica 20051001

• [Safety and efficacy of hypotonic CDDP intraperitoneal administration for gastric cancer with peritoneal dissemination].

  Gan to kagaku ryoho. Cancer & chemotherapy 20051001

• Methotrexate/misoprostol vs. a more standard approach for termination of pregnancies of undetermined location: a randomized, controlled trial.

  The Journal of reproductive medicine 20051001

• Wegener granulomatosis presenting as bilateral loss of vision.

  Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20051001

• Primary intraocular lymphoma arising during methotrexate treatment of temporal arteritis.

  Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 20051001

• Response to initial treatment of low and intermediate risk gestational trophoblastic disease with methotrexate and folinic acid.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20051001

• Development of a large-scale chemogenomics database to improve drug candidate selection and to understand mechanisms of chemical toxicity and action.

  Journal of biotechnology 20050929

• Poly(amidoamine) dendrimer-based multifunctional engineered nanodevice for cancer therapy.

  Journal of medicinal chemistry 20050922

• Primary biliary cirrhosis.

  The New England journal of medicine 20050922

• Translocation of a long amino-terminal domain through ER membrane by following signal-anchor sequence.

  The EMBO journal 20050921

• Low-dose chemotherapy for Epstein-Barr virus-positive post-transplantation lymphoproliferative disease in children after solid organ transplantation.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050920

• Does timing of adjuvant chemotherapy influence the prognosis after early breast cancer? Results of the Danish Breast Cancer Cooperative Group (DBCG).

  British journal of cancer 20050919

• Tolerability of cyclosphosphamide and methotrexate induction immunosuppression in nonhuman primates.

  Toxicology 20050915

• Novel 5-substituted, 2,4-diaminofuro[2,3-d]pyrimidines as multireceptor tyrosine kinase and dihydrofolate reductase inhibitors with antiangiogenic and antitumor activity.

  Bioorganic & medicinal chemistry 20050915

• Expression profiles of osteosarcoma that can predict response to chemotherapy.

  Cancer research 20050915

• ABCG2 harboring the Gly482 mutation confers high-level resistance to various hydrophilic antifolates.

  Cancer research 20050915

• Methotrexate-modified superparamagnetic nanoparticles and their intracellular uptake into human cancer cells.

  Langmuir : the ACS journal of surfaces and colloids 20050913

• Cyclin A as a marker for prognosis and chemotherapy response in advanced breast cancer.

  British journal of cancer 20050905

• Treatment continuation in patients receiving biological agents or conventional DMARD therapy.

  Annals of the rheumatic diseases 20050901

• Multicentric reticulohistiocytosis associated with rheumatoid arthritis.

  Rheumatology international 20050901

• Effectiveness of systematic monitoring of rheumatoid arthritis disease activity in daily practice: a multicentre, cluster randomised controlled trial.

  Annals of the rheumatic diseases 20050901

• Effects and interaction of 7-hydroxy methotrexate and methotrexate in leukaemic cells ex vivo measured by the thymidylate synthase inhibition assay.

  Cancer chemotherapy and pharmacology 20050901

• The reduced folate carrier gene is a novel selectable marker for recombinant protein overexpression.

  Molecular pharmacology 20050901

• Breast cancer recurrence dynamics following adjuvant CMF is consistent with tumor dormancy and mastectomy-driven acceleration of the metastatic process.

  Annals of oncology : official journal of the European Society for Medical Oncology 20050901

• Primary chemotherapy in operable breast carcinoma comparing CMF (cyclophosphamide, methotrexate, 5-fluorouracil) with an anthracycline-containing regimen: short-term responses translated into long-term outcomes.

  Annals of oncology : official journal of the European Society for Medical Oncology 20050901

• Pharmaceutical liquid crystals: the relevance of partially ordered systems.

  Journal of pharmaceutical sciences 20050901

• Methotrexate for Crohn's disease: experience in a district general hospital.

  European journal of gastroenterology & hepatology 20050901

• Bendamustine prolongs progression-free survival in metastatic breast cancer (MBC): a phase III prospective, randomized, multicenter trial of bendamustine hydrochloride, methotrexate and 5-fluorouracil (BMF) versus cyclophosphamide, methotrexate and 5-fluorouracil (CMF) as first-line treatment of MBC.

  Anti-cancer drugs 20050901

• Successful treatment with adalimumab in infliximab-resistant Crohn's disease.

  Journal of gastroenterology and hepatology 20050901

• Cyclophosphamide and antithymocyte globulin as a conditioning regimen for allogeneic marrow transplantation in patients with aplastic anaemia: a long-term follow-up.

  British journal of haematology 20050901

• Breast conservation after neoadjuvant chemotherapy for stage II carcinoma of the breast.

  Journal of the American College of Surgeons 20050901

• Nuclear winter.

  Transfusion 20050901

• The classic: recent advances in chemotherapy of metastatic osteogenic sarcoma. 1972.

  Clinical orthopaedics and related research 20050901

• The activities of purine-catabolizing enzymes and the level of nitric oxide in rat kidneys subjected to methotrexate: protective effect of caffeic acid phenethyl ester.

  Molecular and cellular biochemistry 20050901

• Incidence and prognostic impact of amenorrhea during adjuvant therapy in high-risk premenopausal breast cancer: analysis of a National Cancer Institute of Canada Clinical Trials Group Study--NCIC CTG MA.5.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050901

• Methotrexate-induced status epilepticus.

  American journal of hematology 20050901

• 4-Demethoxy-3'-deamino-3'-aziridinyl-4'-methylsulphonyl-daunorubicin (PNU-159548): a promising new candidate for chemotherapeutic treatment of osteosarcoma patients.

  European journal of cancer (Oxford, England : 1990) 20050901

• Influence of methylenetetrahydrofolate reductase polymorphisms on efficacy and toxicity of methotrexate in patients with juvenile idiopathic arthritis.

  The Journal of rheumatology 20050901

• Rapid improvement of calcinosis in juvenile dermatomyositis with alendronate therapy.

  The Journal of rheumatology 20050901

• A survey of Canadian gastroenterologists about the use of methotrexate in patients with Crohn's disease.

  Canadian journal of gastroenterology = Journal canadien de gastroenterologie 20050901

• Acute cardiac toxicity associated with high-dose intravenous methotrexate therapy: case report and review of the literature.

  Pharmacotherapy 20050901

• Relation between chemotherapy dose, oestrogen receptor expression, and body-mass index.

  Lancet (London, England) 20050901

• Juvenile rheumatoid arthritis with myelofibrosis with myeloid metaplasia.

  Indian journal of pediatrics 20050901

• Secondary analysis of Radiation Therapy Oncology Group study (RTOG) 9310: an intergroup phase II combined modality treatment of primary central nervous system lymphoma.

  Journal of neuro-oncology 20050901

• Identifying good prognosis group of breast cancer patients with 1-3 positive axillary nodes for adjuvant cyclophosphamide, methotrexate and 5-fluorouracil (CMF) chemotherapy.

  Japanese journal of clinical oncology 20050901

• [Chemotherapy for brain tumor].

  Nihon rinsho. Japanese journal of clinical medicine 20050901

• [Cardiac effects of cytokines produced after rituximab infusion].

  Bulletin du cancer 20050901

• [Peripheral mononuclear cells and cytokine circulating levels during adalimumab therapy in patients with rheumatoid arthritis].

  Recenti progressi in medicina 20050901

• A comparison of the outcomes of non-randomised chemotherapy regimens in node positive breast cancer.

  Journal of experimental & clinical cancer research : CR 20050901

• [The influence of IL-6 polymorphism on efficacy of treatment of rheumatoid arthritis patients with methotrexate and prednisone].

  Polskie Archiwum Medycyny Wewnetrznej 20050901

• The relationship between folate transport activity at low pH and reduced folate carrier function in human Huh7 hepatoma cells.

  Biochimica et biophysica acta 20050830

• Persistent nicotine treatment potentiates amplification of the dihydrofolate reductase gene in rat lung epithelial cells as a consequence of Ras activation.

  The Journal of biological chemistry 20050826

• [Recurrent aseptic osteonecrosis in Crohn's disease - extraintestinal manifestation or steroid related complication?].

  Deutsche medizinische Wochenschrift (1946) 20050826

• [Symmetric polyarthritis in a patient with Churg-Strauss syndrome].

  Deutsche medizinische Wochenschrift (1946) 20050819

• Near-final word on adjuvant chemotherapy for breast cancer is good news.

  Journal of the National Cancer Institute 20050817

• Enhanced glucose absorption in the rat small intestine following repeated doses of 5-fluorouracil.

  Chemico-biological interactions 20050815

• Synthesis of classical, four-carbon bridged 5-substituted furo[2,3-d]pyrimidine and 6-substituted pyrrolo[2,3-d]pyrimidine analogues as antifolates.

  Journal of medicinal chemistry 20050811

• [Effects of primary chemotherapy with single methotrexate on low-risk gestational trophoblastic neoplasia and influencing factors thereof].

  Zhonghua yi xue za zhi 20050810

• HPLC analysis of PAMAM dendrimer based multifunctional devices.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050805

• Pharmacogenetic and metabolite measurements are associated with clinical status in patients with rheumatoid arthritis treated with methotrexate: results of a multicentred cross sectional observational study.

  Annals of the rheumatic diseases 20050801

• Cost effectiveness of etanercept (Enbrel) in combination with methotrexate in the treatment of active rheumatoid arthritis based on the TEMPO trial.

  Annals of the rheumatic diseases 20050801

• Methotrexate preconditioning allows sufficient engraftment to confer drug resistance in mice transplanted with marrow expressing drug-resistant dihydrofolate reductase activity.

  The Journal of pharmacology and experimental therapeutics 20050801

• Methotrexate-induced pancytopenia: serious and under-reported? Our experience of 25 cases in 5 years.

  Rheumatology (Oxford, England) 20050801

• Disease-modifying antirheumatic drug use in the elderly rheumatoid arthritis patient.

  Clinics in geriatric medicine 20050801

• Adjuvant chemotherapy for elderly patients (> or =70 years) with early high-risk breast cancer: a retrospective analysis of 260 patients.

  Annals of oncology : official journal of the European Society for Medical Oncology 20050801

• Cold agglutinin disease associated with adenovirus infection after allogeneic bone marrow transplantation.

  Bone marrow transplantation 20050801

• Bladder cancer 'adjuvant-lite': tastes great (works as well) and less filling (less toxic)?

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050801

• Adjuvant cisplatin plus methotrexate versus methotrexate, vinblastine, epirubicin, and cisplatin in locally advanced bladder cancer: results of a randomized, multicenter, phase III trial (AUO-AB 05/95).

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050801

• Hyperfractionated cyclophosphamide with high-doses of arabinosylcytosine and methotrexate (HyperCHiDAM Verona 897).

  Cancer 20050801

• Unrelated donor bone marrow transplantation for 100 pediatric patients: a single institute's experience.

  Bone marrow transplantation 20050801

• Safety and potential efficacy of low-dose methotrexate for treatment of chronic graft-versus-host disease.

  Bone marrow transplantation 20050801

• Efficiency of combined methotrexate/chloroquine therapy in adjuvant-induced arthritis.

  Fundamental & clinical pharmacology 20050801

• Prospective evaluation of renal function in pediatric and adult patients treated with high-dose ifosfamide, cisplatin and high-dose methotrexate.

  Anti-cancer drugs 20050801

• Methotrexate-loaded biodegradable polymeric micelles: preparation, physicochemical properties and in vitro drug release.

  Colloids and surfaces. B, Biointerfaces 20050801

• Randomized trial comparing cyclophosphamide, epirubicin, and fluorouracil with cyclophosphamide, methotrexate, and fluorouracil in premenopausal women with node-positive breast cancer: update of National Cancer Institute of Canada Clinical Trials Group Trial MA5.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050801

• Randomized trial of cyclophosphamide versus methotrexate for induction of remission in early systemic antineutrophil cytoplasmic antibody-associated vasculitis.

  Arthritis and rheumatism 20050801

• Genetically based resistance to the antiinflammatory effects of methotrexate in the air-pouch model of acute inflammation.

  Arthritis and rheumatism 20050801

• Three-year oral clodronate treatment does not impair mineralization of newly formed bone--a histomorphometric study.

  Calcified tissue international 20050801

• Retroperitoneal fibrosis and ankylosing spondylitis: which links?

  Seminars in arthritis and rheumatism 20050801

• Diffusion-weighted MR imaging of early methotrexate-related neurotoxicity in children.

  AJNR. American journal of neuroradiology 20050801

• B-cell lymphoma of the larynx in a patient with rheumatoid arthritis.

  The Journal of laryngology and otology 20050801

• In vitro sustained human transscleral drug delivery of fluorescein-labeled dexamethasone and methotrexate with fibrin sealant.

  Current eye research 20050801

• [Stage IV gastric cancer patient who underwent palliative gastrectomy showing complete response to induction therapy with methotrexate plus 5-fluorouracil and secondary treatment with oral TS-1].

  Gan to kagaku ryoho. Cancer & chemotherapy 20050801

• Ornithine decarboxylase prevents methotrexate-induced apoptosis by reducing intracellular reactive oxygen species production.

  Apoptosis : an international journal on programmed cell death 20050801

• HER2 overexpression as a predictive marker in a randomized trial comparing adjuvant cyclophosphamide/methotrexate/5-fluorouracil with epirubicin in patients with stage I/II breast cancer: long-term results.

  Clinical breast cancer 20050801

• Methotrexate-paclitaxel-epirubicin-carboplatin (M-TEC) combination chemotherapy in patients with advanced bladder cancer: an open label phase II study.

  Journal of chemotherapy (Florence, Italy) 20050801

• [Mice transduced with double-mutant dihydrofolate reductase-cytidine deaminase fusion gene attained protection from high dose chemotherapy].

  Zhonghua wai ke za zhi [Chinese journal of surgery] 20050801

• First-time manifestation of giant-cell arteritis during methotrexate treatment.

  Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20050801

• Thermo-chemo-radiotherapy for advanced bile duct carcinoma.

  World journal of gastroenterology 20050721

• Randomized phase III trial of cisplatin with or without topotecan in carcinoma of the uterine cervix: a Gynecologic Oncology Group Study.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050720

• Long-term survival results of a randomized trial comparing gemcitabine plus cisplatin, with methotrexate, vinblastine, doxorubicin, plus cisplatin in patients with bladder cancer.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050720

• Immunosuppressant and immunomodulatory treatment for dermatomyositis and polymyositis.

  The Cochrane database of systematic reviews 20050720

• Methotrexate for primary biliary cirrhosis.

  The Cochrane database of systematic reviews 20050720

• Effect of polymorphisms in folate-related genes on in vitro methotrexate sensitivity in pediatric acute lymphoblastic leukemia.

  Blood 20050715

• Modified ProMACE-MOPP hybrid regimen with moderate-dose methotrexate for patients with primary CNS lymphoma.

  Annals of hematology 20050701

• Venorelbine and methotrexate for the treatment of Rosai-Dorfman disease.

  Pediatric blood & cancer 20050701

• AIDS-related Burkitt's lymphoma versus diffuse large-cell lymphoma in the pre-highly active antiretroviral therapy (HAART) and HAART eras: significant differences in survival with standard chemotherapy.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050701

• Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.

  Journal of pharmaceutical sciences 20050701

• Predictive value of in vitro assessment of cytotoxic drug activity in advanced breast cancer.

  Anti-cancer drugs 20050701

• The role of preoperative radiotherapy in nonmetastatic high-grade osteosarcoma of the extremities for limb-sparing surgery.

  International journal of radiation oncology, biology, physics 20050701

• Combination of copper-chelating agent, trientine, and methotrexate attenuates colorectal carcinoma development and angiogenesis in mice.

  Oncology reports 20050701

• Oral effects of low-dose methotrexate treatment.

  Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20050701

• Modulation of orphan nuclear receptor NURR1 expression by methotrexate in human inflammatory joint disease involves adenosine A2A receptor-mediated responses.

  Journal of immunology (Baltimore, Md. : 1950) 20050701

• Patterns of toxicity in older patients with breast cancer receiving adjuvant chemotherapy.

  Breast cancer research and treatment 20050701

• Clinical images: Radiographic healing of osseous sarcoidosis.

  Arthritis and rheumatism 20050701

• Neovascularization and neoinnervation of subcutaneously placed nucleus pulposus and the inhibitory effects of certain drugs.

  Spine 20050701

• Highly active antiretroviral therapy and outcome of AIDS-related Burkitt's lymphoma or leukemia. Results of the PETHEMA-LAL3/97 study.

  Haematologica 20050701

• [Effectiveness of methotrexate for the escape by salazosulfapyridine].

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20050701

• Late magnetic resonance imaging features of leukoencephalopathy in children with central nervous system tumours following high-dose methotrexate and neuraxis radiation therapy.

  European journal of cancer (Oxford, England : 1990) 20050701

• Pulsed high-dose corticosteroids combined with low-dose methotrexate in severe localized scleroderma.

  Archives of dermatology 20050701

• Localization and differential activity of P-glycoprotein in the bovine olfactory and nasal respiratory mucosae.

  Pharmaceutical research 20050701

• 'Atrophic telogen effluvium' from cytotoxic drugs and a randomized controlled trial to investigate the possible protective effect of pretreatment with a topical vitamin D analogue in humans.

  The British journal of dermatology 20050701

• Subungual verrucous carcinoma of the thumb treated by intra-arterial infusion with methotrexate.

  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20050701

• Evaluation of the efficacy of mifepristone/misoprostol and methotrexate/misoprostol for medical abortion.

  Indian journal of medical sciences 20050701

• Rosai-Dorfman disease: successful long-term results by combination chemotherapy with prednisone, 6-mercaptopurine, methotrexate, and vinblastine: a case report.

  International journal of surgical pathology 20050701

• Primary intracranial dural lymphoma of mucosa-associated lymphoid tissue (MALT) type: report of one case and review of the literature.

  Bulletin du cancer 20050701

• Low dose methotrexate induces apoptosis with reactive oxygen species involvement in T lymphocytic cell lines to a greater extent than in monocytic lines.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20050701

• Treatment results of methotrexate and folinic acid as primary chemotherapy for nonmetastatic gestational trophoblastic neoplasia.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20050701

• [Effective treatment for a methotrexate-associated lymphoproliferative disorder with R-CHOP following administration of rituximab].

  [Rinsho ketsueki] The Japanese journal of clinical hematology 20050701

• Co-localization and interaction of organic anion transporter 1 with caveolin-2 in rat kidney.

  Experimental & molecular medicine 20050630

• Chemotherapy for breast cancer during pregnancy: an 18-year experience from five London teaching hospitals.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050620

• Potential risk of a common hereditary thrombophilia and adjuvant chemotherapy for low-stage breast cancer.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050620

• Identification of amino acids required for the functional up-regulation of human dihydrofolate reductase protein in response to antifolate Treatment.

  The Journal of biological chemistry 20050617

• Pharmacogenetics of outcome in children with acute lymphoblastic leukemia.

  Blood 20050615

• Nanoparticle targeting of anticancer drug improves therapeutic response in animal model of human epithelial cancer.

  Cancer research 20050615

• In vitro and in vivo methotrexate disposition in alveolar macrophages: comparison of pharmacokinetic parameters of two formulations.

  International journal of pharmaceutics 20050613

• Targeting and inhibition of cell growth by an engineered dendritic nanodevice.

  Journal of medicinal chemistry 20050602

• A randomised, double blind, placebo controlled, multicentre trial of combination therapy with methotrexate plus ciclosporin in patients with active psoriatic arthritis.

  Annals of the rheumatic diseases 20050601

• Diagnosis and monitoring a case of light-chain deposition disease in the kidney using a new, sensitive immunoassay.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20050601

• Cyclosporine A and mycophenolate mofetil vs cyclosporine A and methotrexate for graft-versus-host disease prophylaxis after stem cell transplantation from HLA-identical siblings.

  Bone marrow transplantation 20050601

• Cyclosporin A and mini short-term methotrexate vs cyclosporin A as graft-versus-host disease prophylaxis in patients with beta thalassemia major undergoing allogeneic blood and marrow transplantation.

  Bone marrow transplantation 20050601

• Rat reduced-folate carrier-1 is localized basolaterally in MDCK kidney epithelial cells and contributes to the secretory transport of methotrexate and fluoresceinated methotrexate.

  Cell and tissue research 20050601

• Overexpression of AP endonuclease protects Leishmania major cells against methotrexate induced DNA fragmentation and hydrogen peroxide.

  Molecular and biochemical parasitology 20050601

• Pharmacokinetic study of methotrexate following intra-articular injection of methotrexate loaded poly(L-lactic acid) microspheres in rabbits.

  Journal of pharmaceutical sciences 20050601

• Survival of adults treated for medulloblastoma using paediatric protocols.

  European journal of cancer (Oxford, England : 1990) 20050601

• Fungal infections as a complication of therapy for sarcoidosis.

  QJM : monthly journal of the Association of Physicians 20050601

• Long-term survival in locally advanced oral cavity cancer: an analysis of patients treated with neoadjuvant cisplatin-based chemotherapy followed by surgery.

  Head & neck 20050601

• Methotrexate related adverse effects in patients with RA.

  Annals of the rheumatic diseases 20050601

• Low-dose methotrexate: a mainstay in the treatment of rheumatoid arthritis.

  Pharmacological reviews 20050601

• Haematopoietic stem cell transplantation in haemophagocytic lymphohistiocytosis.

  British journal of haematology 20050601

• High folic acid levels and failure of single-dose methotrexate treatment in ectopic pregnancy.

  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20050601

• Viable cervical pregnancy with levonorgestrel containing intrauterine device, treated successfully with methotrexate and mifepristone.

  European journal of obstetrics, gynecology, and reproductive biology 20050601

• Frequency, predictors, and economic impact of upward dose adjustment of infliximab in managed care patients with rheumatoid arthritis.

  Journal of managed care pharmacy : JMCP 20050601

• Long-term follow-up of patients with birdshot retinochoroidopathy treated with corticosteroid-sparing systemic immunomodulatory therapy.

  Ophthalmology 20050601

• Reversible optic neuropathy associated with low-dose methotrexate therapy.

  Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society 20050601

• Prolonged perturbation of the oscillations of hepatoma Fao cell proliferation by a single small dose of methotrexate.

  Pathologie-biologie 20050601

• Lymphomatoid papulosis in a patient with atopic eczema on long-term ciclosporin therapy.

  The British journal of dermatology 20050601

• Management of leptomeningeal malignancy.

  Expert opinion on pharmacotherapy 20050601

• [The treatment of juvenile rheumatism: pharmacotherapy].

  Zeitschrift fur Rheumatologie 20050601

• [Reducing toxicity of methotrexate with folic acid].

  Zeitschrift fur Rheumatologie 20050601

• Human embryonic stem cell methyl cycle enzyme expression: modelling epigenetic programming in assisted reproduction?

  Reproductive biomedicine online 20050601

• Comparison of multidose and single-dose methotrexate protocols for the treatment of ectopic pregnancy.

  American journal of obstetrics and gynecology 20050601

• [A case of head and neck squamous cell carcinoma suffering from acute renal failure after methotrexate administrator].

  Gan to kagaku ryoho. Cancer & chemotherapy 20050601

• [Graft-versus-ATLL effect induced by abrupt discontinuation of immunosuppression following allogeneic bone marrow transplantation].

  Gan to kagaku ryoho. Cancer & chemotherapy 20050601

• IgG immune response to tumor-associated carbohydrate antigens (TF, Tn, alphaGal) in patients with breast cancer: impact of neoadjuvant chemotherapy and relation to the survival.

  Experimental oncology 20050601

• Herpes simplex encephalitis as a complication of adjuvant chemotherapy treatment for breast cancer.

  Clinical oncology (Royal College of Radiologists (Great Britain)) 20050601

• Transplant-finalized salvage of adult acute lymphoblastic leukemia: results of a mitoxantrone- and methotrexate-based regimen in 36 patients.

  Leukemia & lymphoma 20050601

• No evidence of association of methylenetetrahydrofolate reductase polymorphism with occurrence of second neoplasms after treatment of childhood leukemia.

  Leukemia & lymphoma 20050601

• [Pyogenic spondylitis by methicillin-resistant Staphylococcus aureus (MRSA) during M-VAC therapy: a case report].

  Hinyokika kiyo. Acta urologica Japonica 20050601

• Chronic plaque psoriasis.

  Clinical evidence 20050601

• Assessment of ovarian failure and osteoporosis in premenopausal breast cancer survivors.

  Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners 20050601

• Complex karyotypic abnormalities in a case of acute myeloid leukaemia--M4Eo.

  The Malaysian journal of pathology 20050601

• [Individual monitoring of thiopurine and methotrexate treatment].

  Ugeskrift for laeger 20050516

• The human multidrug resistance protein MRP5 transports folates and can mediate cellular resistance against antifolates.

  Cancer research 20050515

• Capillary electrophoretic determination of methotrexate, leucovorin and folic acid in human urine.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050505

• Acute erythroleukemia in a rheumatoid arthritis patient during low-dose methotrexate therapy.

  Rheumatology international 20050501

• Synthesis and drug release behavior of poly (trimethylene carbonate)-poly (ethylene glycol)-poly (trimethylene carbonate) nanoparticles.

  Biomaterials 20050501

• Expression, localization, and functional characteristics of breast cancer resistance protein in Caco-2 cells.

  Drug metabolism and disposition: the biological fate of chemicals 20050501

• A new high-performance liquid chromatographic/electrospray ionization tandem mass spectrometric method for the simultaneous determination of cyclophosphamide, methotrexate and 5-fluorouracil as markers of surface contamination for occupational exposure monitoring.

  Journal of mass spectrometry : JMS 20050501

• Value of intravenous 6-mercaptopurine during continuation treatment in childhood acute lymphoblastic leukemia and non-Hodgkin's lymphoma: final results of a randomized phase III trial (58881) of the EORTC CLG.

  Leukemia 20050501

• Involvement of P-gp in the process of apoptosis in peripheral blood mononuclear cells.

  International immunopharmacology 20050501

• Worse survival for TP53 (p53)-mutated breast cancer patients receiving adjuvant CMF.

  Annals of oncology : official journal of the European Society for Medical Oncology 20050501

• Severe vertigo requiring hospitalization whilst taking low-dose oral methotrexate for psoriasis.

  Clinical and experimental dermatology 20050501

• Timing of CMF chemotherapy in combination with tamoxifen in postmenopausal women with breast cancer: role of endocrine responsiveness of the tumor.

  Annals of oncology : official journal of the European Society for Medical Oncology 20050501

• Alteration of the organ uptake of the (99m)Tc-radiopharmaceuticals, (99m)Tc-DPD, (99m)Tc-DMSA, (99m)Tc-tin colloid and (99m)Tc-MAA, induced by the applied cytotoxic drugs methotrexate sodium and cyclophosphamide.

  Nuclear medicine communications 20050501

• Determining patient preferences for improved chemotoxicity during treatment for advanced bladder cancer.

  European journal of cancer care 20050501

• Inhibitors of histone deacetylases alter kinetochore assembly by disrupting pericentromeric heterochromatin.

  Cell cycle (Georgetown, Tex.) 20050501

• Mucositis after allogeneic hematopoietic stem cell transplantation: a cohort study of methotrexate- and non-methotrexate-containing graft-versus-host disease prophylaxis regimens.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20050501

• Preliminary neutron diffraction studies of Escherichia coli dihydrofolate reductase bound to the anticancer drug methotrexate.

  Acta crystallographica. Section D, Biological crystallography 20050501

• Dermatoses of pregnancy update.

  Journal of the American Academy of Dermatology 20050501

• Methotrexate-induced bullous acral erythema in a child.

  Journal of the American Academy of Dermatology 20050501

• Cauda equina and conus medullaris syndrome in sarcoidosis.

  The neurologist 20050501

• Secondary chemotherapy for high-risk gestational trophoblastic neoplasia.

  Gynecologic oncology 20050501

• Expectant, medical, or surgical management of first-trimester miscarriage: a meta-analysis.

  Obstetrics and gynecology 20050501

• Anomalies associated with failed methotrexate and misoprostol termination.

  Obstetrics and gynecology 20050501

• A mutation in the drug transporter gene ABCC2 associated with impaired methotrexate elimination.

  Pharmacogenetics and genomics 20050501

• Methotrexate suppresses inflammatory agonist induced interleukin 6 synthesis in osteoblasts.

  The Journal of rheumatology 20050501

• Etanercept treatment in patients with refractory systemic onset juvenile rheumatoid arthritis.

  The Journal of rheumatology 20050501

• Hydroxychloroquine does not decrease serum methotrexate concentrations in children with juvenile idiopathic arthritis.

  Arthritis and rheumatism 20050501

• Prevalence of leukoencephalopathy in children treated for acute lymphoblastic leukemia with high-dose methotrexate.

  AJNR. American journal of neuroradiology 20050501

• Myelopathy due to intrathecal chemotherapy: report of six cases.

  Journal of pediatric hematology/oncology 20050501

• Vincristine-induced urinary bladder paralysis.

  Journal of pediatric hematology/oncology 20050501

• The multidrug resistance protein 5 (ABCC5) confers resistance to 5-fluorouracil and transports its monophosphorylated metabolites.

  Molecular cancer therapeutics 20050501

• Effects of calcineurin inhibitors on an in vitro assay for chronic urticaria.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20050501

• Methotrexate therapy of oral corticosteroid-dependent asthmatics reduces serum immunoglobulins: correlation with clinical response to therapy.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20050501

• High-dose methotrexate in acute lymphoblastic leukemia: where is the evidence for its continued use?

  Pharmacotherapy 20050501

• Primary central nervous system lymphoma: a single-centre experience of 55 unselected cases.

  Clinical oncology (Royal College of Radiologists (Great Britain)) 20050501

• Transport mechanism and substrate specificity of human organic anion transporter 2 (hOat2 [SLC22A7]).

  The Journal of pharmacy and pharmacology 20050501

• [Relapsing polychondritis -- a case report and review of the literature].

  Laryngo- rhino- otologie 20050501

• Capillary electrophoretic determination of triamterene, methotrexate, and creatinine in human urine.

  Journal of separation science 20050501

• [Leucovorin rescue after continuing infusion of high dose methotrexate].

  Zhonghua er ke za zhi = Chinese journal of pediatrics 20050501

• Transient encephalopathy after intrathekal methotrexate chemotherapy: diffusion-weighted MRI.

  Journal of neuro-oncology 20050501

• [Sarcoidosis--immunological features and clinical issues].

  Nihon rinsho. Japanese journal of clinical medicine 20050501

• [Methotrexate].

  Nihon rinsho. Japanese journal of clinical medicine 20050501

• [Trial of front-line intensive chemotherapy followed by peripheral blood stem cell transplantation in high-intermediate and high risk non-Hodgkin's lymphoma patients].

  [Rinsho ketsueki] The Japanese journal of clinical hematology 20050501

• Methotrexate determination in pharmaceuticals by enantioselective HPLC.

  Journal of pharmaceutical and biomedical analysis 20050429

• Leflunomide or methotrexate for juvenile rheumatoid arthritis.

  The New England journal of medicine 20050421

• Re: Treatment of accidental intrathecal methotrexate overdose.

  Journal of the National Cancer Institute 20050420

• Neuropsychological outcome after chemotherapy for primary CNS lymphoma: a prospective study.

  Neurology 20050412

• Expression of resistance markers to methotrexate predicts clinical improvement in patients with rheumatoid arthritis.

  Annals of the rheumatic diseases 20050401

• Long-term results of dose density therapy in patients with aggressive lymphoma.

  Annals of hematology 20050401

• Folic acid supplementation during methotrexate treatment: nonsense?

  Rheumatology (Oxford, England) 20050401

• Preoperative sequential chemotherapy in locally advanced squamous cell carcinoma of the head and neck.

  Head & neck 20050401

• Accumulation of methotrexate and methotrexate polyglutamates in lymphoblasts and treatment outcome in children with B-progenitor-cell acute lymphoblastic leukemia: a Pediatric Oncology Group study.

  Leukemia 20050401

• Interactions of carboxypeptidase G2 with 6S-leucovorin and 6R-leucovorin in vitro: implications for the application in case of methotrexate intoxications.

  Cancer chemotherapy and pharmacology 20050401

• Non-total body irradiation containing preparative regimen in alternative donor bone marrow transplantation for severe aplastic anemia.

  Bone marrow transplantation 20050401

• Comparison of pulse methotrexate and pulse dactinomycin in the treatment of low-risk gestational trophoblastic neoplasia.

  The Australian & New Zealand journal of obstetrics & gynaecology 20050401

• Synthesis and in vitro antitumor activity of 4(3H)-quinazolinone derivatives with dithiocarbamate side chains.

  Bioorganic & medicinal chemistry letters 20050401

• Primary stage I-IIE non-Hodgkin's lymphoma of uterine cervix and upper vagina: evidence for a conservative approach in a study on three patients.

  Gynecologic oncology 20050401

• Neoadjuvant combined chemotherapy followed by external whole pelvic irradiation in two cases of primary extranodal non-Hodgkin's lymphoma of the uterine cervix.

  Gynecologic oncology 20050401

• Psoriasis-induced postoperative cardiac failure.

  The Annals of thoracic surgery 20050401

• Primary CNS lymphoma of T-cell origin: a descriptive analysis from the international primary CNS lymphoma collaborative group.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050401

• Physical function and health related quality of life: analysis of 2-year data from randomized, controlled studies of leflunomide, sulfasalazine, or methotrexate in patients with active rheumatoid arthritis.

  The Journal of rheumatology 20050401

• Reversing myocardial microvascular disease in a patient with rheumatoid arthritis.

  The Journal of rheumatology 20050401

• A phase II trial of sequential chemotherapy with docetaxel and methotrexate followed by gemcitabine and cisplatin for metastatic urothelial cancer.

  American journal of clinical oncology 20050401

• The effects of ondansetron and granisetron on electrocardiography in children receiving chemotherapy for acute leukemia.

  American journal of clinical oncology 20050401

• The effect of Bcrp1 (Abcg2) on the in vivo pharmacokinetics and brain penetration of imatinib mesylate (Gleevec): implications for the use of breast cancer resistance protein and P-glycoprotein inhibitors to enable the brain penetration of imatinib in patients.

  Cancer research 20050401

• Nephrotic syndrome in patients with peripheral blood stem cell transplant.

  American journal of kidney diseases : the official journal of the National Kidney Foundation 20050401

• Predicting response to methotrexate, vinblastine, doxorubicin, and cisplatin neoadjuvant chemotherapy for bladder cancers through genome-wide gene expression profiling.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20050401

• Folic acid and folinic acid supplements and methotrexate therapy: comment on the article by Morgan et al.

  Arthritis and rheumatism 20050401

• Continuous indices of core data set measures in rheumatoid arthritis clinical trials: lower responses to placebo than seen with categorical responses with the American College of Rheumatology 20% criteria.

  Arthritis and rheumatism 20050401

• [Clinical randomized comparative trial of ProMACE-CytaBOM regimen and CHOP regimen in treating non-Hodgkin's lymphoma].

  Ai zheng = Aizheng = Chinese journal of cancer 20050401

• [Treatment effect of percutaneous vertebroplasty combined with interventional chemotherapy on vertebral metastases].

  Ai zheng = Aizheng = Chinese journal of cancer 20050401

• Traditional therapies in the management of moderate to severe chronic plaque psoriasis: an assessment of the benefits and risks.

  The British journal of dermatology 20050401

• Adjuvant anthracycline-based chemotherapy for early breast cancer: do the dose and schedule matter?

  Cancer treatment reviews 20050401

• [Modified pharmacokinetic modulating chemotherapy for progressive gastric cancer accompanied by peritoneal dissemination].

  Gan to kagaku ryoho. Cancer & chemotherapy 20050401

• [A case of advanced gastric cancer with bone metastasis and severe DIC responding to hypertensive subselective chemotherapy with pharmacokinetic modulating chemotherapy].

  Gan to kagaku ryoho. Cancer & chemotherapy 20050401

• Functional analysis of polymorphisms in the organic anion transporter, SLC22A6 (OAT1).

  Pharmacogenetics and genomics 20050401

• The current status of perioperative chemotherapy for invasive bladder cancer: a multiinstitutional retrospective study in Japan.

  International journal of clinical oncology 20050401

• Antiinflammatory therapies for cystic fibrosis: past, present, and future.

  Pharmacotherapy 20050401

• Polymorphisms of genes controlling homocysteine levels and IQ score following the treatment for childhood ALL.

  Pharmacogenomics 20050401

• Modern modified 'ultra' Goeckerman therapy: a PASI assessment of a very effective therapy for psoriasis resistant to both prebiologic and biologic therapies.

  The Journal of dermatological treatment 20050401

• Preparation and characterization of a biodegradable drug targeting system for anticancer drug delivery: microsphere-antibody conjugate.

  Journal of drug targeting 20050401

• Combination of gemcitabine and irinotecan for recurrent metastatic osteogenic sarcoma.

  Clinical advances in hematology & oncology : H&O 20050401

• Carboxypeptidase-G2 rescue in a patient with high dose methotrexate-induced nephrotoxicity.

  Cancer research and treatment : official journal of Korean Cancer Association 20050401

• Interference of 7-hydroxymethotrexate with the determination of methotrexate in plasma samples from children with acute lymphoblastic leukemia employing routine clinical assays.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050325

• Beware of the unilateral red eye: don't miss blinding uveitis.

  The Medical journal of Australia 20050321

• Sequencing of chemotherapy and radiation therapy in early-stage breast cancer: updated results of a prospective randomized trial.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050320

• Osteosarcoma: a randomized, prospective trial of the addition of ifosfamide and/or muramyl tripeptide to cisplatin, doxorubicin, and high-dose methotrexate.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050320

• Methylenetetrahydrofolate reductase polymorphisms and therapy response in pediatric acute lymphoblastic leukemia.

  Cancer research 20050315

• Treatment of early childhood medulloblastoma by postoperative chemotherapy alone.

  The New England journal of medicine 20050310

• MTX-induced white matter changes are associated with polymorphisms of methionine metabolism.

  Neurology 20050308

• The 2000 Burkitt lymphoma trial in Malawi.

  Pediatric blood & cancer 20050301

• The treatment of primary central nervous system lymphoma in 122 immunocompetent patients: a population-based study of successively treated cohorts from the British Colombia Cancer Agency.

  Cancer 20050301

• High-dose methotrexate toxicity in elderly patients with primary central nervous system lymphoma.

  Annals of oncology : official journal of the European Society for Medical Oncology 20050301

• Combined chemotherapy with carmustine, doxorubicin, etoposide, vincristine, and cyclophosphamide plus mitoxantrone, cytarabine and methotrexate with citrovorum factor for the treatment of aggressive non-Hodgkin lymphoma: a long-term follow-up study.

  Cancer 20050301

• Course of mental fatigue and motivation in breast cancer patients receiving adjuvant chemotherapy.

  Annals of oncology : official journal of the European Society for Medical Oncology 20050301

• FK506 ameliorates spontaneous locomotor activity in collagen-induced arthritis: implication of distinct effect from suppression of inflammation.

  International immunopharmacology 20050301

• Sarcomas of the head and neck. Results from the treatment of 25 patients.

  European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 20050301

• Relapse rate of patients with low-risk gestational trophoblastic tumor initially treated with single-agent chemotherapy.

  Gynecologic oncology 20050301

• Can we alter the natural history of Crohn disease in children?

  Journal of pediatric gastroenterology and nutrition 20050301

• Thiopurine methyltransferase in acute lymphoblastic leukaemia: biochemical and molecular biological aspects.

  European journal of cancer (Oxford, England : 1990) 20050301

• [Examination of the escape phenomenon in disease modifying antirheumatic drugs].

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20050301

• Combination nonviral interleukin-2 gene immunotherapy for head and neck cancer: from bench top to bedside.

  The Laryngoscope 20050301

• A woman who couldn't speak: report of methotrexate neurotoxicity.

  Postgraduate medical journal 20050301

• Methotrexate for psoriasis: current European practice. A postal survey.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20050301

• Comparison of ARF after myeloablative and nonmyeloablative hematopoietic cell transplantation.

  American journal of kidney diseases : the official journal of the National Kidney Foundation 20050301

• [Clinical analysis of resectable breast cancer: a report of 6 263 cases].

  Ai zheng = Aizheng = Chinese journal of cancer 20050301

• Traditional systemic treatments have not fully met the needs of psoriasis patients: results from a national survey.

  Journal of the American Academy of Dermatology 20050301

• [Case of central nervous system lymphoma metastasized to breast after remission by methotrexate chemotherapy].

  No shinkei geka. Neurological surgery 20050301

• Monitoring patients on methotrexate: hepatic fibrosis not seen in patients with normal serum assays of aminoterminal peptide of type III procollagen.

  The British journal of dermatology 20050301

• [Treatment with leflunomide in rheumatoid arthritis].

  Zeitschrift fur Rheumatologie 20050301

• Quantitative thallium-201 scintigraphy in childhood osteosarcoma: Comparison with technetuim-99m MDP and magnetic resonance imaging in the evaluation of chemotherapeutic response.

  Pediatric hematology and oncology 20050301

• Acral erythema caused by high-dose methotrexate therapy in patients with osteogenic sarcoma.

  Pediatric hematology and oncology 20050301

• [Minutes of the 23th meeting of the European Society for Therapeutic Radiology and Oncology (ESTRO). Amsterdam, 24-28 October 2004].

  Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique 20050301

• Combining traditional agents and biologics for the treatment of psoriasis.

  Seminars in cutaneous medicine and surgery 20050301

• [The clinical spectrum of dermatomyositis].

  Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20050301

• Polyuria associated with high-dose methotrexate in two patients with acute lymphoblastic leukaemia.

  Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners 20050301

• Clinical role of multidrug resistance protein 1 expression in chemotherapy resistance in early-stage breast cancer: the Austrian Breast and Colorectal Cancer Study Group.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050220

• Preradiation chemotherapy with methotrexate, cisplatin, 5-fluorouracil, and leucovorin for pediatric nasopharyngeal carcinoma.

  Cancer 20050215

• Primary chemotherapy with cyclophosphamide, methotrexate, and 5-fluorouracil in operable breast carcinoma.

  Cancer 20050215

• Review article: monitoring of immunomodulators in inflammatory bowel disease.

  Alimentary pharmacology & therapeutics 20050215

• An 19F magnetic resonance-based in vivo assay of solid tumor methotrexate resistance: proof of principle.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20050215

• A randomised factorial trial of sequential doxorubicin and CMF vs CMF and chemotherapy alone vs chemotherapy followed by goserelin plus tamoxifen as adjuvant treatment of node-positive breast cancer.

  British journal of cancer 20050214

• Carboxypeptidase G2 rescue in patients with methotrexate intoxication and renal failure.

  British journal of cancer 20050214

• Long term safety of methotrexate in routine clinical care: discontinuation is unusual and rarely the result of laboratory abnormalities.

  Annals of the rheumatic diseases 20050201

• Motexafin gadolinium generates reactive oxygen species and induces apoptosis in sensitive and highly resistant multiple myeloma cells.

  Blood 20050201

• Human organic anion transporter MRP4 (ABCC4) is an efflux pump for the purine end metabolite urate with multiple allosteric substrate binding sites.

  American journal of physiology. Renal physiology 20050201

• Transport of bile acids, sulfated steroids, estradiol 17-beta-D-glucuronide, and leukotriene C4 by human multidrug resistance protein 8 (ABCC11).

  Molecular pharmacology 20050201

• The anti-inflammatory action of methotrexate is not mediated by lymphocyte apoptosis, but by the suppression of activation and adhesion molecules.

  Clinical immunology (Orlando, Fla.) 20050201

• Expression and purification of recombinant human angiopoietin-2 produced in Chinese hamster ovary cells.

  Protein expression and purification 20050201

• The effect of methotrexate and glucocorticosteroids on apoptosis of phythemaglutinin-stimulated mononuclear cells from peripheral blood.

  Fundamental & clinical pharmacology 20050201

• Chemoresistant placental site trophoblastic tumor with hilar lymph node metastasis: an unusual site of involvement.

  Gynecologic oncology 20050201

• Neoadjuvant chemotherapy with cyclophosphamide, mitoxantrone, and 5-fluorouracil in locally advanced breast cancer.

  Onkologie 20050201

• Good clinical response of breast cancers to neoadjuvant chemoendocrine therapy is associated with improved overall survival.

  Annals of oncology : official journal of the European Society for Medical Oncology 20050201

• The outcome of elderly patients with advanced urothelial carcinoma after platinum-based combination chemotherapy.

  Annals of oncology : official journal of the European Society for Medical Oncology 20050201

• Modulation of IMPDH2, survivin, topoisomerase I and vimentin increases sensitivity to methotrexate in HT29 human colon cancer cells.

  The FEBS journal 20050201

• Single amino acid (482) variants of the ABCG2 multidrug transporter: major differences in transport capacity and substrate recognition.

  Biochimica et biophysica acta 20050201

• Understanding the role of Leu22 variants in methotrexate resistance: comparison of wild-type and Leu22Arg variant mouse and human dihydrofolate reductase ternary crystal complexes with methotrexate and NADPH.

  Acta crystallographica. Section D, Biological crystallography 20050201

• Methotrexate toxicity induced by acute renal failure.

  Journal of the Royal Society of Medicine 20050201

• Methotrexate reduces incidence of vascular diseases in veterans with psoriasis or rheumatoid arthritis.

  Journal of the American Academy of Dermatology 20050201

• Bilateral ocular myositis as a late complication of dermatomyositis.

  The Journal of rheumatology 20050201

• HLA-B27 associated spondyloarthropathy, vasculitis, and amyloid enteropathy: response to infliximab.

  The Journal of rheumatology 20050201

• Second induction in pediatric patients with recurrent acute lymphoid leukemia using DFCI-ALL protocols.

  Journal of pediatric hematology/oncology 20050201

• Small cell carcinoma of bladder: a single-center prospective study of 25 cases treated in analogy to small cell lung cancer.

  Urology 20050201

• [Treatment of childhood Burkitt lymphoma according to LMB89 protocol in Casablanca].

  Bulletin du cancer 20050201

• [A patient with metastatic breast cancer associated with retention of pleural effusion with no response to both CMF and exemestane, whose life was saved by high-dose toremifene].

  Gan to kagaku ryoho. Cancer & chemotherapy 20050201

• Available options in chemotherapy for advanced gastric cancer: the current developments in Japan.

  Expert opinion on pharmacotherapy 20050201

• Cognitive changes in children treated for acute lymphoblastic leukemia with chemotherapy only according to the Pediatric Oncology Group 9605 protocol.

  Journal of child neurology 20050201

• [Etopside, methotrexate, kengshengmycin/etopside, cisplatin chemotherapy for chemorefractory gestational trophoblastic tumour].

  Zhonghua fu chan ke za zhi 20050201

• [Study on the indication of surgical resection of pulmonary metastasis of malignant trophoblastic tumor].

  Zhonghua fu chan ke za zhi 20050201

• [Assessment of staging and prognostic scoring system for malignant trophoblastic neoplasia].

  Zhonghua fu chan ke za zhi 20050201

• [Clinical analysis of 13 cases of gestational trophoblastic tumor misdiagnosed as ectopic pregnancy].

  Zhonghua fu chan ke za zhi 20050201

• [Protective effects of transplantation of hCNTF-transfected cell line on axotomy-induced degeneration of retinal ganglion cells].

  [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20050201

• Rheumatoid arthritis: an update.

  Delaware medical journal 20050201

• Systemic treatment for moderate to severe psoriasis: estimates of failure rates and direct medical costs in a north-eastern US managed care plan.

  The Journal of dermatological treatment 20050201

• Over-expression, purification, and characterization of recombinant human arylamine N-acetyltransferase 1.

  The protein journal 20050201

• 30 years' follow up of randomised studies of adjuvant CMF in operable breast cancer: cohort study.

  BMJ (Clinical research ed.) 20050129

• Exploring the role of different drug transport routes in permeability screening.

  Journal of medicinal chemistry 20050127

• Methotrexate and oral ulceration.

  British dental journal 20050122

• Advanced-stage large-cell lymphoma in children and adolescents: results of a randomized trial incorporating intermediate-dose methotrexate and high-dose cytarabine in the maintenance phase of the APO regimen: a Pediatric Oncology Group phase III trial.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050120

• Locoregional radiation therapy in patients with high-risk breast cancer receiving adjuvant chemotherapy: 20-year results of the British Columbia randomized trial.

  Journal of the National Cancer Institute 20050119

• Low tumor cell density environment yields survival advantage of tumor cells exposed to MTX in vitro.

  Biochimica et biophysica acta 20050118

• Adjuvant sequential methotrexate --> 5-fluorouracil vs 5-fluorouracil plus leucovorin in radically resected stage III and high-risk stage II colon cancer.

  British journal of cancer 20050117

• Arginine-482 is not essential for transport of antibiotics, primary bile acids and unconjugated sterols by the human breast cancer resistance protein (ABCG2).

  The Biochemical journal 20050115

• [Erdheim-Chester disease].

  Deutsche medizinische Wochenschrift (1946) 20050107

• Folate pathway gene expression differs in subtypes of acute lymphoblastic leukemia and influences methotrexate pharmacodynamics.

  The Journal of clinical investigation 20050103

• An open, randomized comparison study of cyclosporine A, cyclosporine A + methotrexate and cyclosporine A + hydroxychloroquine in the treatment of early severe rheumatoid arthritis.

  Rheumatology international 20050101

• Estimated prediagnosis radiological progression: an important tool for studying the effects of early disease modifying antirheumatic drug treatment in rheumatoid arthritis.

  Annals of the rheumatic diseases 20050101

• A good response to early DMARD treatment of patients with rheumatoid arthritis in the first year predicts remission during follow up.

  Annals of the rheumatic diseases 20050101

• Preservation of folate transport activity with a low-pH optimum in rat IEC-6 intestinal epithelial cell lines that lack reduced folate carrier function.

  American journal of physiology. Cell physiology 20050101

• Down syndrome, drug metabolism and chromosome 21.

  Pediatric blood & cancer 20050101

• Adenosine and methotrexate polyglutamate concentrations in patients with juvenile arthritis.

  Rheumatology (Oxford, England) 20050101

• Genomic screening and complications of hematopoietic stem cell transplantation: has the time come?

  Bone marrow transplantation 20050101

• Lack of an effect of breast cancer resistance protein (BCRP/ABCG2) overexpression on methotrexate polyglutamate export and folate accumulation in a human breast cancer cell line.

  Biochemical pharmacology 20050101

• Cologne high-dose sequential chemotherapy in relapsed and refractory Hodgkin lymphoma: results of a large multicenter study of the German Hodgkin Lymphoma Study Group (GHSG).

  Annals of oncology : official journal of the European Society for Medical Oncology 20050101

• Interlaboratory validation of a CD71-based flow cytometric method (Microflow) for the scoring of micronucleated reticulocytes in mouse peripheral blood.

  Environmental and molecular mutagenesis 20050101

• Leukoencephalopathy around a tumor cyst following intracystic methotrexate injection.

  Pediatric neurology 20050101

• Intermittent rises in plasma homocysteine in patients with rheumatoid arthritis treated with higher dose methotrexate.

  Annals of the rheumatic diseases 20050101

• Sensitization of human erythroleukemia K562 cells resistant to methotrexate by inhibiting IMPDH.

  Medical science monitor : international medical journal of experimental and clinical research 20050101

• Systemic therapy does not usually clear psoriasis, but treatment success does not require clearing.

  Journal of the American Academy of Dermatology 20050101

• Multicentric reticulohistiocytosis with prominent cutaneous lesions and proximal muscle weakness masquerading as dermatomyositis.

  The Journal of rheumatology 20050101

• Images in haematology. Combined central retinal artery and vein occlusions as the presenting signs of ocular relapse in acute lymphoblastic leukaemia.

  British journal of haematology 20050101

• Response to chemotherapy and treating institution predict survival in primary central nervous system lymphoma.

  British journal of haematology 20050101

• Intrathecal chemotherapy for patients with meningeal carcinomatosis.

  Surgical neurology 20050101

• Early suppression of disease activity is essential for maintenance of work capacity in patients with recent-onset rheumatoid arthritis: five-year experience from the FIN-RACo trial.

  Arthritis and rheumatism 20050101

• Presentation and analysis of data on radiographic outcome in clinical trials: experience from the TEMPO study.

  Arthritis and rheumatism 20050101

• Long-term survival in high-grade axial osteosarcoma with bone and lung metastases treated with chemotherapy only.

  Journal of pediatric hematology/oncology 20050101

• Cervical pregnancy treated with transvaginal ultrasound-guided intra-amniotic instillation of methotrexate.

  Archives of gynecology and obstetrics 20050101

• [The second-line chemotherapy for urological cancers].

  Gan to kagaku ryoho. Cancer & chemotherapy 20050101

• Proton magnetic resonance spectroscopy in immunocompetent patients with primary central nervous system lymphoma.

  Journal of neuro-oncology 20050101

• [Panuveitis as a possible ophthalmic complication of Kikuchi-Fujimoto disease].

  Archivos de la Sociedad Espanola de Oftalmologia 20050101

• Q-TWiST analysis of cyclophosphamide, epirubicin, fluorouracil versus cyclophosphamide, methotrexate, fluorouracil treatment for premenopausal women with node-positive breast cancer.

  PharmacoEconomics 20050101

• Natural killer T-cell lymphoma of the tongue.

  The Annals of otology, rhinology, and laryngology 20050101

• Reversal of cirrhosis in a patient with primary biliary cirrhosis-autoimmune hepatitis overlap syndrome.

  Digestive diseases and sciences 20050101

• Medical termination of pregnancy in the early first trimester.

  The journal of family planning and reproductive health care 20050101

• The ability of disease modifying antirheumatic drugs to induce and maintain improvement in patients with rheumatoid arthritis. epidemiology of DMARDs treatment in Japan.

  Clinical and experimental rheumatology 20050101

• Practices for managing a flare of long-standing rheumatoid arthritis: survey among French rheumatologists.

  Clinical and experimental rheumatology 20050101

• Compliance and toxicity of adjuvant CMF in elderly breast cancer patients: a single-center experience.

  BMC cancer 20050101

• [Guidelines for RA therapies].

  Nihon rinsho. Japanese journal of clinical medicine 20050101

• [Treatment of juvenile idiopathic arthritis].

  Nihon rinsho. Japanese journal of clinical medicine 20050101

• [Disease modifying anti-rheumatic drugs (DMARDs): an overview].

  Nihon rinsho. Japanese journal of clinical medicine 20050101

• [Methotrexate for therapy of rheumatoid arthritis].

  Nihon rinsho. Japanese journal of clinical medicine 20050101

• [Combination drug therapy in rheumatoid arthritis].

  Nihon rinsho. Japanese journal of clinical medicine 20050101

• [Adverse effects of DMARDs in treatment of rheumatoid arthritis].

  Nihon rinsho. Japanese journal of clinical medicine 20050101

• [Tailor-made medicine and genomic drug discovery in rheumatoid arthritis].

  Nihon rinsho. Japanese journal of clinical medicine 20050101

• Treatment of acute lymphocytic leukemia using zinc adjuvant with chemotherapy and radiation--a case history and hypothesis.

  Medical hypotheses 20050101

• Acute transient cerebral toxicity associated with administration of high-dose methotrexate.

  Medical principles and practice : international journal of the Kuwait University, Health Science Centre 20050101

• Osteogenic progenitor cell potency after high-dose chemotherapy (COSS-96).

  Anticancer research 20050101

• Disease-modifying antirheumatic drugs and bone mass in rheumatoid arthritis.

  Clinical and experimental rheumatology 20050101

• Post-treatment residual tissue in idiopathic retroperitoneal fibrosis: active residual disease or silent 'scar' ? A study using 18F-fluorodeoxyglucose positron emission tomography.

  Clinical and experimental rheumatology 20050101

• Urinary excretion of alpha-GST and albumin in rheumatoid arthritis patients treated with methotrexate or other DMARDs alone or in combination with NSAIDs.

  Scandinavian journal of rheumatology 20050101

• Probable psychiatric side effects of azathioprine.

  Psychosomatic medicine 20050101

• Response time and safety profile of pulsed oral methotrexate therapy in idiopathic retinal periphlebitis.

  European journal of ophthalmology 20050101

• [Study on elimination delay in high dose methotrexate therapy in childhood acute lymphoblastic leukemia].

  Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20050101

• [Evaluation of compliance through specific interviews: a prospective study of 73 children with acute lymphoblastic leukemia].

  Jornal de pediatria 20050101

• Chorioretinitis as a complication of pauciarticular juvenile rheumatoid arthritis.

  Journal of pediatric ophthalmology and strabismus 20050101

• Methotrexate induction of human sulfotransferases in Hep G2 and Caco-2 cells.

  Journal of applied toxicology : JAT 20050101

• Preoperative second-line chemotherapy induces objective responses in primary breast cancer.

  Wiener klinische Wochenschrift 20050101

• Primary cutaneous nocardiosis in 2 patients on immunosuppressants.

  Scandinavian journal of infectious diseases 20050101

• EMA-EP Regimen, as first line multiple agent chemotherapy in high risk GTD patients (stage II-IV).

  International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20050101

• [Medical abortion using methotrexate and misoprostol. Efficacy and tolerability].

  Akusherstvo i ginekologiia 20050101

• Treatment of intravenous immunoglobulin-resistant Kawasaki disease with methotrexate.

  Scandinavian journal of rheumatology 20050101

• Exacerbation of Whipple's disease associated with infliximab treatment.

  Scandinavian journal of rheumatology 20050101

• Methotrexate use in rheumatoid arthritis is associated with few clinically significant liver function test abnormalities.

  Clinical and experimental rheumatology 20050101

• Sensitisation of Ehrlich ascitic tumour cells to methotrexate by inhibiting glutaminase.

  Anticancer research 20050101

• Glucose transporter GLUT1 in colorectal adenocarcinoma cell lines is inversely correlated with tumour cell proliferation.

  Anticancer research 20050101

• Management of the upper extremity in juvenile rheumatoid arthritis.

  The Journal of the American Academy of Orthopaedic Surgeons 20050101

• Chemoprevention by pyrimethamine.

  Immunopharmacology and immunotoxicology 20050101

• [Treatment of adult Berkitt-like lymphoma].

  Terapevticheskii arkhiv 20050101

• High dose methotrexate in adult patients with osteosarcoma: clinical and pharmacokinetic results.

  Acta oncologica (Stockholm, Sweden) 20050101

• In vivo effects of high-dose methotrexate on bone remodeling in rats.

  Pharmacological reports : PR 20050101

• Pancytopenia induced by low-dose methotrexate. A study of the cases reported to the Finnish Adverse Drug Reaction Register From 1991 to 1999.

  Scandinavian journal of rheumatology 20050101

• [Relapsing polychondritis. A case report of a patient treated with methotrexate and celecoxib].

  Revista medica del Instituto Mexicano del Seguro Social 20050101

• Effect of creatinine clearance on patterns of toxicity in older patients receiving adjuvant chemotherapy for breast cancer.

  Drugs & aging 20050101

• Long-term follow-up of patients with birdshot retinochoroidopathy treated with systemic immunosuppression.

  Ocular immunology and inflammation 20050101

• Severe encephalopathy induced by the first but not the second course of high-dose methotrexate mirrored by plasma homocysteine elevations and preceded by extreme differences in pretreatment plasma folate.

  Oncology 20050101

• Treatment of acute promyelocytic leukemia: a single institution experience.

  Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion 20050101

• [Psoriatic arthritis: combined treatment with prospidin and methotrexate].

  Terapevticheskii arkhiv 20050101

• [Efficacy of different chemotherapy programs, indications for surgery and radiotherapy in primary mediastinal B-cell lymphosarcoma].

  Terapevticheskii arkhiv 20050101

• Adjuvant fluorouracil, epirubicin and cyclophosphamide in early breast cancer: is it cost-effective?

  Acta oncologica (Stockholm, Sweden) 20050101

• [Methotrexate for the treatment of patients with chronic cutaneous sarcoidosis: 4 cases].

  Annales de dermatologie et de venereologie 20050101

• Optimal management of severe plaque form of psoriasis.

  American journal of clinical dermatology 20050101

• Treatment of pemphigus vulgaris: current and emerging options.

  American journal of clinical dermatology 20050101

• Adjuvant chemotherapy in 780 patients with early breast cancer: 10-year data from Saudi Arabia.

  Medical oncology (Northwood, London, England) 20050101

• High-dose methotrexate and/or leucovorin rescue for the treatment of children with lymphoblastic malignancies: do we really know why, when and how?

  Neoplasma 20050101

• Have methotrexate-induced liver fibrosis and cirrhosis become rare? A matter for reappraisal of routine liver biopsies.

  Dermatology (Basel, Switzerland) 20050101

• Puerto Rico psoriasis study group: efficacy and safety of etanercept.

  Journal of drugs in dermatology : JDD 20050101

• Prognostic impact of age in children and adolescents with acute lymphoblastic leukemia: data from the trials ALL-BFM 86, 90, and 95.

  Klinische Padiatrie 20050101

• Effect of anticancer agents on codeinone-induced apoptosis in human cancer cell lines.

  Anticancer research 20050101

• A liver fibrosis cocktail? Psoriasis, methotrexate and genetic hemochromatosis.

  BMC dermatology 20050101

• [Treatment results of Langerhans cell histiocytosis with LSH II protocol].

  Casopis lekaru ceskych 20050101

• Methotrexate causes oxidative stress in rat kidney tissues.

  Renal failure 20050101

• Severe hepatotoxicity in a rheumatoid arthritis patient switched from leflunomide to methotrexate.

  MedGenMed : Medscape general medicine 20050101

• Mediterranean diet or extended fasting's influence on changing the intestinal microflora, immunoglobulin A secretion and clinical outcome in patients with rheumatoid arthritis and fibromyalgia: an observational study.

  BMC complementary and alternative medicine 20050101

• Aurothiomalate and hydroxychloroquine inhibit nitric oxide production in chondrocytes and in human osteoarthritic cartilage.

  Scandinavian journal of rheumatology 20050101

• Transient absorption spectra and kinetics of folic acid (vitamin B11) and some kinetic data of folinic acid and methotrexate.

  Oncology research 20050101

• Artemether: a new therapeutic strategy in experimental rheumatoid arthritis.

  Immunopharmacology and immunotoxicology 20050101

• [The individual differences in responses of cancer patient blood cells on radiation treatment during the chemotherapy].

  Radiatsionnaia biologiia, radioecologiia 20050101

• [Meningeal carcinomatosis in cancer patients].

  Tumori 20050101

• Effect of intracerebroventricular methotrexate on brain amines.

  Indian journal of physiology and pharmacology 20050101

• Disease modifying treatment for feline rheumatoid arthritis.

  Veterinary and comparative orthopaedics and traumatology : V.C.O.T 20050101

• [Systemic management of autoimmune anterior uveitis].

  Klinika oczna 20050101

• Influence of tumor necrosis factor α in rheumatoid arthritis.

  GMS health technology assessment 20050101

• A mathematical model of the folate cycle: new insights into folate homeostasis.

  The Journal of biological chemistry 20041231

• Benzoyl ring halogenated classical 2-amino-6-methyl-3,4-dihydro-4-oxo-5-substituted thiobenzoyl-7H-pyrrolo[2,3-d]pyrimidine antifolates as inhibitors of thymidylate synthase and as antitumor agents.

  Journal of medicinal chemistry 20041230

• Synthesis of classical, three-carbon-bridged 5-substituted furo[2,3-d]pyrimidine and 6-substituted pyrrolo[2,3-d]pyrimidine analogues as antifolates.

  Journal of medicinal chemistry 20041230

• Synthesis and in vitro antifolate activity of rotationally restricted aminopterin and methotrexate analogues.

  Journal of medicinal chemistry 20041230

• Use of combination therapy with immunomodulators and immunosuppressants in treating multiple sclerosis.

  Neurology 20041228

• Growth phase regulation of the main folate transporter of Leishmania infantum and its role in methotrexate resistance.

  The Journal of biological chemistry 20041224

• Disparate mechanisms of antifolate resistance provoked by methotrexate and its metabolite 7-hydroxymethotrexate in leukemia cells: implications for efficacy of methotrexate therapy.

  Blood 20041215

• Association of peripheral multifocal choroiditis with sarcoidosis: a study of thirty-seven patients.

  Arthritis and rheumatism 20041215

• Adjuvant chemotherapy for lymph node-negative, estrogen receptor-negative breast cancer: a tale of three trials.

  Journal of the National Cancer Institute 20041215

• Treatment of axillary lymph node-negative, estrogen receptor-negative breast cancer: updated findings from National Surgical Adjuvant Breast and Bowel Project clinical trials.

  Journal of the National Cancer Institute 20041215

• Feasibility and response to induction chemotherapy intensified with high-dose methotrexate for young children with newly diagnosed high-risk disseminated medulloblastoma.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20041215

• Unusual sites of metastatic malignancy: case 3. Acute leukemia presenting as bilateral proptosis.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20041215

• Antifolate resistance in a HeLa cell line associated with impaired transport independent of the reduced folate carrier.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20041215

• Coexistence of treatment-related MLL cleavage and rearrangement in a child with haemophagocytic lymphohistiocytosis.

  British journal of cancer 20041213

• [Treatment of primary mediastinal large B-cell lymphomas].

  Orvosi hetilap 20041212

• Methotrexate enhances prostaglandin D2-stimulated heat shock protein 27 induction in osteoblasts.

  Prostaglandins, leukotrienes, and essential fatty acids 20041201

• Comparing vaginal and buccal misoprostol when used after methotrexate for early abortion.

  Contraception 20041201

• Effects of folylpolyglutamate synthetase modulation on chemosensitivity of colon cancer cells to 5-fluorouracil and methotrexate.

  Gut 20041201

• Leflunomide inhibits transendothelial migration of peripheral blood mononuclear cells.

  Annals of the rheumatic diseases 20041201

• Enhanced Fcgamma receptor I, alphaMbeta2 integrin receptor expression by monocytes and neutrophils in rheumatoid arthritis: interaction with platelets.

  The Journal of rheumatology 20041201

• Folate, homocysteine, and cobalamin status in patients with rheumatoid arthritis treated with methotrexate, and the effect of low dose folic acid supplement.

  The Journal of rheumatology 20041201

• Guidelines for blood test monitoring of methotrexate toxicity in juvenile idiopathic arthritis.

  The Journal of rheumatology 20041201

• [Pneumocystis pneumonia -- atypical manifestation in an immunosuppressed patient with rheumatoid arthritis].

  RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin 20041201

• Homocysteine: exploring its potential as a pharmacodynamic biomarker of antifolate chemotherapy.

  Pharmacogenomics 20041201

• Effects of disease-modifying antirheumatic drugs and antiinflammatory cytokines on human osteoclastogenesis through interaction with receptor activator of nuclear factor kappaB, osteoprotegerin, and receptor activator of nuclear factor kappaB ligand.

  Arthritis and rheumatism 20041201

• [Efficacy of modified BFM-90 regimen on children and adolescents with T cell lymphoblastic lymphoma: a report of 20 cases].

  Ai zheng = Aizheng = Chinese journal of cancer 20041201

• Clinical outcomes of patients treated for cervical pregnancy with or without methotrexate.

  Journal of Korean medical science 20041201

• Effect of organic isothiocyanates on breast cancer resistance protein (ABCG2)-mediated transport.

  Pharmaceutical research 20041201

• Crohn's disease over 20 years after diagnosis in a referral population.

  Gastroenterologie clinique et biologique 20041201

• [Two cases of retroperitoneal liposarcoma arisen from perirenal fat tissue, which could not be diagnosed preoperatively].

  Hinyokika kiyo. Acta urologica Japonica 20041201

• The 'alphabet' of rheumatoid arthritis treatment.

  Medsurg nursing : official journal of the Academy of Medical-Surgical Nurses 20041201

• [The effects of interleukin-11 on high-dose methotrexate (HDMTX) induced mucositis in Wistar rats].

  Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20041201

• Methotrexate in resistant ENL.

  International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association 20041201

• [Respiratory complications of new treatments for rheumatoid arthritis].

  Revue des maladies respiratoires 20041201

• Isolated central nervous system blast crisis in chronic myeloid leukemia.

  Hematological oncology 20041201

• Quantifying trade-offs: quality of life and quality-adjusted survival in a randomised trial of chemotherapy in postmenopausal patients with lymph node-negative breast cancer.

  British journal of cancer 20041129

• [Haemopericardium in rheumatoid arthritis treated with methotrexate].

  Ugeskrift for laeger 20041122

• [Ankylosing spondylitis].

  Presse medicale (Paris, France : 1983) 20041120

• Multidrug resistance protein 4 (ABCC4)-mediated ATP hydrolysis: effect of transport substrates and characterization of the post-hydrolysis transition state.

  The Journal of biological chemistry 20041119

• Risk-adapted, combined-modality therapy with VAMP/COP and response-based, involved-field radiation for unfavorable pediatric Hodgkin's disease.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20041115

• Restoration of transport activity by co-expression of human reduced folate carrier half-molecules in transport-impaired K562 cells: localization of a substrate binding domain to transmembrane domains 7-12.

  The Journal of biological chemistry 20041105

• Patient preferences for treatment of rheumatoid arthritis.

  Annals of the rheumatic diseases 20041101

• Combined donor leucocyte administration and immunosuppressive drug treatment for survival of rat heart allografts.

  Transplant immunology 20041101

• Immunosuppressants, infection, and inflammation.

  Clinical immunology (Orlando, Fla.) 20041101

• Patterns of locoregional failure in patients with operable breast cancer treated by mastectomy and adjuvant chemotherapy with or without tamoxifen and without radiotherapy: results from five National Surgical Adjuvant Breast and Bowel Project randomized clinical trials.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20041101

• Breast tumour growth inhibition in vitro through the combination of cyclophosphamide/metotrexate/5-fluorouracil, epirubicin/cyclophosphamide, epirubicin/paclitaxel, and epirubicin/docetaxel with the bisphosphonates ibandronate and zoledronic acid.

  Oncology reports 20041101

• Acute promyelocytic leukemia and HIV-1 infection: case report and review of the literature.

  American journal of hematology 20041101

• [What have we learned about giant cell arteritis during the last decade?].

  La Revue de medecine interne 20041101

• Tumor excision and reconstruction of the upper cervical spine: a multidisciplinary approach.

  Plastic and reconstructive surgery 20041101

• Antisense glutaminase inhibition decreases glutathione antioxidant capacity and increases apoptosis in Ehrlich ascitic tumour cells.

  European journal of biochemistry 20041101

• Delayed-type hypersensitivity reaction with iscador M given in combination with cytotoxic chemotherapy.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20041101

• Same gain, less pain: potential patient preferences for adjuvant treatment in premenopausal women with early breast cancer.

  European journal of cancer (Oxford, England : 1990) 20041101

• The pseudopapilledema of neonatal-onset multisystem inflammatory disease.

  American journal of ophthalmology 20041101

• Absorption of intravesically applied drugs: comparison of normal and ileal augmented rabbit bladder.

  The Journal of urology 20041101

• Clinical presentation and treatment outcome of children with Burkitt lymphoma in Lebanon: a single institution's experience.

  Journal of pediatric hematology/oncology 20041101

• Oxidative stress contributes to methotrexate-induced small intestinal toxicity in rats.

  Scandinavian journal of gastroenterology 20041101

• Contribution of common polymorphisms in reduced folate carrier and gamma-glutamylhydrolase to methotrexate polyglutamate levels in patients with rheumatoid arthritis.

  Pharmacogenetics 20041101

• [Primary study of relationship between serum level of VEGF and non-Hodgkin's lymphoma in children and adolescent patients].

  Ai zheng = Aizheng = Chinese journal of cancer 20041101

• Efficacy of conventional immunosuppressive drugs in IBD.

  Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20041101

• Damage control in rheumatoid arthritis. Hard-hitting, early treatment is crucial to curbing joint destruction.

  Postgraduate medicine 20041101

• Transferrin-oligomers as potential carriers in anticancer drug delivery.

  Pharmaceutical research 20041101

• [Carcinomatous meningitis from urothelial carcinoma of bladder and ureter: case report].

  Nihon Hinyokika Gakkai zasshi. The japanese journal of urology 20041101

• Recent advances in primary CNS lymphoma.

  Current opinion in oncology 20041101

• Uridine diphosphoglucuronosyl transferase and methylenetetrahydrofolate reductase polymorphisms as genomic predictors of toxicity and response to irinotecan-, antifolate- and fluoropyrimidine-based chemotherapy.

  Journal of chemotherapy (Florence, Italy) 20041101

• [The practice guideline 'Photo(chemo)therapy and systemic therapy in severe chronic plaque-psoriasis'].

  Nederlands tijdschrift voor geneeskunde 20041023

• Treatment of accidental intrathecal methotrexate overdose with intrathecal carboxypeptidase G2.

  Journal of the National Cancer Institute 20041020

• Phase II study of a triplet regimen in advanced colorectal cancer using methotrexate, oxaliplatin and 5-fluorouracil.

  British journal of cancer 20041018

• Restriction of de novo nucleotide biosynthesis interferes with clonal expansion and differentiation into effector and memory CD8 T cells.

  Journal of immunology (Baltimore, Md. : 1950) 20041015

• [Chronic inflammatory bowel diseases].

  Deutsche medizinische Wochenschrift (1946) 20041015

• A spinal cord intravascular lymphomatosis with exceptionally good outcome.

  Neurology 20041012

• Summaries for patients. Prednisone plus methotrexate for polymyalgia rheumatica.

  Annals of internal medicine 20041005

• Prednisone plus methotrexate for polymyalgia rheumatica: a randomized, double-blind, placebo-controlled trial.

  Annals of internal medicine 20041005

• Methotrexate in polymyalgia rheumatica: kernel of truth or curse of Tantalus?

  Annals of internal medicine 20041005

• Two is better than one? Combination therapy in rheumatoid arthritis.

  Rheumatology (Oxford, England) 20041001

• Quality of adjuvant CMF chemotherapy for node-positive primary breast cancer: a population-based study.

  Journal of cancer research and clinical oncology 20041001

• Successful treatment of rheumatoid arthritis is associated with a reduction in serum sE-selectin and thrombomodulin level.

  Clinical rheumatology 20041001

• A prospective randomized trial comparing cyclosporine and short course methotrexate with cyclosporine and mycophenolate mofetil for GVHD prophylaxis in myeloablative allogeneic bone marrow transplantation.

  Bone marrow transplantation 20041001

• Lumiracoxib does not affect methotrexate pharmacokinetics in rheumatoid arthritis patients.

  The Annals of pharmacotherapy 20041001

• Review article: chronic active disease and maintaining remission in Crohn's disease.

  Alimentary pharmacology & therapeutics 20041001

• Decrease of anti-cyclic citrullinated peptide antibodies and rheumatoid factor following anti-TNFalpha therapy (infliximab) in rheumatoid arthritis is associated with clinical improvement.

  Annals of the rheumatic diseases 20041001

• Influence of guideline adherence on outcome in a randomised controlled trial on the efficacy of methotrexate with folate supplementation in rheumatoid arthritis.

  Annals of the rheumatic diseases 20041001

• Methotrexate related adverse effects in patients with rheumatoid arthritis are associated with the A1298C polymorphism of the MTHFR gene.

  Annals of the rheumatic diseases 20041001

• Use of immunomodulary agents is difficult in treating autoimmune hepatitis patients.

  Journal of clinical gastroenterology 20041001

• 1-hexylcarbamoyl-5-fluorouracil + cyclophosphamide + tamoxifen versus CMF + tamoxifen in women with lymph node-positive breast cancer after primary surgery: a randomized controlled trial.

  Oncology reports 20041001

• Toxicity and efficacy of intensive chemotherapy for children with acute lymphoblastic leukemia (ALL) after first bone marrow or extramedullary relapse.

  Pediatric blood & cancer 20041001

• Outcome of children with B cell lymphoma in Venezuela with the LMB-89 protocol.

  Pediatric blood & cancer 20041001

• Inhibition of Leishmania major pteridine reductase by 2,4,6-triaminoquinazoline: structure of the NADPH ternary complex.

  Acta crystallographica. Section D, Biological crystallography 20041001

• Aggressive cutaneous T-cell lymphomas after TNFalpha blockade.

  Journal of the American Academy of Dermatology 20041001

• Methotrexate inhibits the glyoxalase system in vivo in children with acute lymphoid leukaemia.

  European journal of cancer (Oxford, England : 1990) 20041001

• Second-order advantage achieved with four-way fluorescence excitation-emission-kinetic data processed by parallel factor analysis and trilinear least-squares. Determination of methotrexate and leucovorin in human urine.

  Analytical chemistry 20041001

• A pleiotropic defect reducing drug accumulation in cisplatin-resistant cells.

  Journal of inorganic biochemistry 20041001

• Chlamydial infection preceding the development of rheumatoid arthritis: a brief report.

  Clinical rheumatology 20041001

• Pharmacogenetics of methotrexate.

  Pharmacogenomics 20041001

• [Bilateral optic neuropathy revealing systemic sarcoidosis].

  La Revue de medecine interne 20041001

• Determination of methotrexate in pharmaceutical formulations by flow injection analysis exploiting the reaction with potassium permanganate.

  Farmaco (Societa chimica italiana : 1989) 20041001

• The effect of folic acid and folinic acid supplements on purine metabolism in methotrexate-treated rheumatoid arthritis.

  Arthritis and rheumatism 20041001

• Safety and efficacy of tumor necrosis factor alpha blockade in systemic lupus erythematosus: an open-label study.

  Arthritis and rheumatism 20041001

• Characterization of pristane-induced arthritis, a murine model of chronic disease: response to antirheumatic agents, expression of joint cytokines, and immunopathology.

  Arthritis and rheumatism 20041001

• Reduction of synovial sublining layer inflammation and proinflammatory cytokine expression in psoriatic arthritis treated with methotrexate.

  Arthritis and rheumatism 20041001

• Glomerular dysfunction, independent of tubular dysfunction, induced by antineoplastic chemotherapy in children.

  Pediatrics international : official journal of the Japan Pediatric Society 20041001

• Unexpected response of hormone-refractory prostate cancer to treatment with an antileukemic chemotherapy regimen.

  Urology 20041001

• Testicular granulocytic sarcoma, a source of diagnostic confusion.

  Urology 20041001

• [Goal and results of the COSS study].

  Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V... 20041001

• A novel breath test for the non-invasive assessment of small intestinal mucosal injury following methotrexate administration in the rat.

  Scandinavian journal of gastroenterology 20041001

• Eisai hyperbilirubinemic rat (EHBR) as an animal model affording high drug-exposure in toxicity studies on organic anions.

  Drug metabolism and pharmacokinetics 20041001

• Methotrexate-loxoprofen interaction: involvement of human organic anion transporters hOAT1 and hOAT3.

  Drug metabolism and pharmacokinetics 20041001

• [Methotrexate-induced interstitial pneumonitis in a child with acute lymphoblastic leukemia].

  [Rinsho ketsueki] The Japanese journal of clinical hematology 20041001

• [Multiple myeloma of the IgD-lambda type invading CNS].

  [Rinsho ketsueki] The Japanese journal of clinical hematology 20041001

• [MTX/CDDP/5-FU double modulation intra-peritoneal chemotherapy for advanced and metastatic gastric cancer--comparison with intra-aortic route and intra-venous route].

  Gan to kagaku ryoho. Cancer & chemotherapy 20041001

• Antimetabolites in the treatment of arthritis: current status of the use of antimetabolites.

  Nucleosides, nucleotides & nucleic acids 20041001

• Two inhibitors of DNA-synthesis lead to inhibition of cytokine production via a different mechanism.

  Nucleosides, nucleotides & nucleic acids 20041001

• Comparison of anti-arthritic properties of leflunomide with methotrexate and FK506: effect on T cell activation-induced inflammatory cytokine production in vitro and rat adjuvant-induced arthritis.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20041001

• Anthracycline vs nonanthracycline adjuvant therapy for breast cancer.

  Oncology (Williston Park, N.Y.) 20041001

• Declines in mortality from acute myocardial infarction in successive incidence and birth cohorts of patients with rheumatoid arthritis.

  Circulation 20040928

• Deleted in colon cancer protein expression in colorectal cancer metastases: a major predictor of survival in patients with unresectable metastatic disease receiving palliative fluorouracil-based chemotherapy.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040915

• Characterization of a folate transporter in HeLa cells with a low pH optimum and high affinity for pemetrexed distinct from the reduced folate carrier.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20040915

• Salvage therapy for primary CNS lymphoma with a combination of rituximab and temozolomide.

  Neurology 20040914

• Enhanced in vitro invasiveness and drug resistance with altered gene expression patterns in a human lung carcinoma cell line after pulse selection with anticancer drugs.

  International journal of cancer 20040910

• [When to begin rheumatism treatment? Initial combination therapy helps fastest].

  MMW Fortschritte der Medizin 20040909

• [Three joints swollen, blood sedimentation increased. Methotrexate to be given immediately?].

  MMW Fortschritte der Medizin 20040909

• Inflammatory bowel disease: management issues during pregnancy.

  Archives of gynecology and obstetrics 20040901

• Comparison of serum nitric oxide levels in active juvenile rheumatoid arthritis with those of patients in remission.

  Rheumatology international 20040901

• Differential effects of leflunomide and methotrexate on cytokine production in rheumatoid arthritis.

  Annals of the rheumatic diseases 20040901

• Fluorescein-methotrexate transport in rat choroid plexus analyzed using confocal microscopy.

  American journal of physiology. Renal physiology 20040901

• Tacrolimus as monotherapy or combined with minidose methotrexate for graft-versus-host disease prophylaxis after allogeneic peripheral blood stem cell transplantation: long-term outcomes.

  Bone marrow transplantation 20040901

• Disseminated histoplasmosis presenting as pancytopenia in a methotrexate-treated patient.

  American journal of hematology 20040901

• A randomised comparative study of the short term clinical and biological effects of intravenous pulse methylprednisolone and infliximab in patients with active rheumatoid arthritis despite methotrexate treatment.

  Annals of the rheumatic diseases 20040901

• Hepatitis B vaccination in children with juvenile idiopathic arthritis.

  Annals of the rheumatic diseases 20040901

• Experience with the use of low-dose methotrexate for inflammatory bowel disease.

  European journal of gastroenterology & hepatology 20040901

• Aberrant methylation in the promoter region of the reduced folate carrier gene is a potential mechanism of resistance to methotrexate in primary central nervous system lymphomas.

  British journal of haematology 20040901

• The treatment of neoplastic meningitis.

  Expert opinion on pharmacotherapy 20040901

• Drug-induced and iatrogenic infiltrative lung disease.

  Clinics in chest medicine 20040901

• Methotrexate and cytarabine inhibit progression of human lymphoma in NOD/SCID mice carrying a mutant dihydrofolate reductase and cytidine deaminase fusion gene.

  Molecular therapy : the journal of the American Society of Gene Therapy 20040901

• Indirect and total costs of early rheumatoid arthritis: a randomized comparison of combined step-down prednisolone, methotrexate, and sulfasalazine with sulfasalazine alone.

  The Journal of rheumatology 20040901

• Risk factors for methotrexate-induced abnormal laboratory monitoring results in patients with rheumatoid arthritis.

  The Journal of rheumatology 20040901

• Critical limb ischaemia associated with chemotherapy for breast cancer.

  Journal of the Royal Society of Medicine 20040901

• Atypical teratoid/rhabdoid tumour with leptomeningeal dissemination in an adult.

  Acta neurochirurgica 20040901

• Results of a randomised phase II study comparing docetaxel with methotrexate in patients with recurrent head and neck cancer.

  European journal of cancer (Oxford, England : 1990) 20040901

• Clinical outcome in patients with locally advanced bladder carcinoma treated with conservative multimodality therapy.

  Urology 20040901

• High response rate and manageable toxicity with an intensive, short-term chemotherapy programme for Burkitt's lymphoma in adults.

  British journal of haematology 20040901

• Dual targeting of Bruton's tyrosine kinase and Janus kinase 3 with rationally designed inhibitors prevents graft-versus-host disease (GVHD) in a murine allogeneic bone marrow transplantation model.

  British journal of haematology 20040901

• [When are drug-eluting stents effective? A critical analysis of the presently available data].

  Zeitschrift fur Kardiologie 20040901

• Short-term intermittent intravenous clodronate in the prevention of bone loss related to chemotherapy-induced ovarian failure.

  Breast cancer research and treatment 20040901

• Signet ring cell adenocarcinoma of the urachus.

  International journal of urology : official journal of the Japanese Urological Association 20040901

• [Soft tissue sarcoma: postoperative chemotherapy].

  Gan to kagaku ryoho. Cancer & chemotherapy 20040901

• [Ulcerative colitis. Chronic active course].

  Zeitschrift fur Gastroenterologie 20040901

• [Immunosuppressive therapy for inflammatory bowel disease: consensus by the Austrian working group on IBD].

  Zeitschrift fur Gastroenterologie 20040901

• Polyglutamation of methotrexate with common polymorphisms in reduced folate carrier, aminoimidazole carboxamide ribonucleotide transformylase, and thymidylate synthase are associated with methotrexate effects in rheumatoid arthritis.

  Arthritis and rheumatism 20040901

• Evaluation of antimitotic activity of Rotula aquatica (Lour): a traditional herb used in treatment of cancer.

  Indian journal of experimental biology 20040901

• Could immunosuppressive drugs reduce recurrence rate after second resection for Crohn disease?

  Inflammatory bowel diseases 20040901

• [Medical treatment of ectopic pregnancy: a randomized clinical trial comparing metotrexate-mifepristone and methotrexate-placebo].

  Journal de gynecologie, obstetrique et biologie de la reproduction 20040901

• Relationship of high pretreatment folic acid level and failure of methotrexate in ectopic pregnancy: a pilot study.

  The Journal of reproductive medicine 20040901

• [Septic shock following intracavitary Bacillus Calmette-Guerin therapy for postcystectomy ureteral cancer].

  Hinyokika kiyo. Acta urologica Japonica 20040901

• [Imaging in acute toxic encephalopathy].

  Journal of neuroradiology. Journal de neuroradiologie 20040901

• Determinants of survival in Nigerians with Burkitt's lymphoma.

  African journal of medicine and medical sciences 20040901

• Combination benefit of a pyrimidylpiperazine derivative (Y-40138) and methotrexate in arthritic rats.

  European journal of pharmacology 20040830

• [Importance of timing of music therapy in chemotherapy of cancer patients].

  Praxis 20040818

• Correlation between ligand-receptor affinity and the transcription readout in a yeast three-hybrid system.

  Biochemistry 20040817

• A co-translational model to explain the in vivo import of proteins into HeLa cell mitochondria.

  The Biochemical journal 20040815

• Clinical practice of immunosuppressive treatments in multiple sclerosis: results of a second international questionnaire.

  Journal of the neurological sciences 20040815

• Receptor binding characteristics and cytotoxicity of insulin-methotrexate.

  World journal of gastroenterology 20040815

• Mechanism of the pharmacokinetic interaction between methotrexate and benzimidazoles: potential role for breast cancer resistance protein in clinical drug-drug interactions.

  Cancer research 20040815

• Differential protein expression analysis of Leishmania major reveals novel roles for methionine adenosyltransferase and S-adenosylmethionine in methotrexate resistance.

  The Journal of biological chemistry 20040806

• Tamoxifen treatment reverses the adverse effects of chemotherapy-induced ovarian failure on serum lipids.

  British journal of cancer 20040802

• Ectopic pregnancy: an update.

  Current opinion in obstetrics & gynecology 20040801

• Treatment with immunosuppressive and anti-inflammatory agents delays onset of canine genetic narcolepsy and reduces symptom severity.

  Experimental neurology 20040801

• Neo-adjuvant chemotherapy for operable gastric cancer: long term results of the Dutch randomised FAMTX trial.

  European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 20040801

• Methotrexate and folic acid: what is the optimal combination?

  Rheumatology (Oxford, England) 20040801

• Anakinra: an inhibitor of IL-1 for the treatment of rheumatoid arthritis.

  Expert opinion on biological therapy 20040801

• Depression: a case of neuronal life and death?

  Biological psychiatry 20040801

• Gemcitabine-associated scleroderma-like changes of the lower extremities.

  Journal of the American Academy of Dermatology 20040801

• Self-resolution of Epstein-Barr virus-associated B-cell lymphoma in a patient with dermatomyositis following withdrawal of mycophenolate mofetil and methotrexate.

  Journal of the American Academy of Dermatology 20040801

• Prolonged fever of unknown origin and hemophagocytosis evolving into acute lymphoblastic leukemia.

  American journal of hematology 20040801

• A substrate specific functional polymorphism of human gamma-glutamyl hydrolase alters catalytic activity and methotrexate polyglutamate accumulation in acute lymphoblastic leukaemia cells.

  Pharmacogenetics 20040801

• Multimodal treatment of children with unresectable or recurrent desmoid tumors: an 11-year longitudinal observational study.

  Journal of pediatric hematology/oncology 20040801

• Organic anion transporter 3 is involved in the brain-to-blood efflux transport of thiopurine nucleobase analogs.

  Journal of neurochemistry 20040801

• Combination leflunomide and methotrexate (MTX) therapy for patients with active rheumatoid arthritis failing MTX monotherapy: open-label extension of a randomized, double-blind, placebo controlled trial.

  The Journal of rheumatology 20040801

• Mucosa-associated lymphoid tissue lymphoma (MALT) of salivary glands and scleroderma: a case report.

  Clinical rheumatology 20040801

• Primary acute lymphoblastic leukemia cells use a novel promoter and 5'noncoding exon for the human reduced folate carrier that encodes a modified carrier translated from an upstream translational start.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20040801

• [Comparing CHOP, CHOP+HD-MTX,and BFM-90 regimens in the survival rate of children and adolescents with B cell non-Hodgkin's lymphoma].

  Ai zheng = Aizheng = Chinese journal of cancer 20040801

• The use of methotrexate in rheumatoid arthritis.

  Seminars in arthritis and rheumatism 20040801

• Determination of the chiral and achiral related substances of methotrexate by cyclodextrin-modified micellar electrokinetic chromatography.

  Electrophoresis 20040801

• Invasive ductal carcinoma within a fibroadenoma of the breast.

  International journal of clinical oncology 20040801

• Placental site trophoblastic tumor: an overview.

  The Journal of reproductive medicine 20040801

• Helping patients to help themselves. Interview by Janis Smy.

  Nursing times 20040801

• [Usefulness of FDG-PET in monitoring effects of the modality therapy for central nervous system malignant lymphoma: report of three cases].

  No shinkei geka. Neurological surgery 20040801

• Rheumatoid arthritis treatment progressing.

  Health news (Waltham, Mass.) 20040801

• [Mismatched hematopoietic stem cell transplantation using GIAC protocol: report of 100 cases].

  Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20040801

• Structural studies on bioactive compounds. 39. Biological consequences of the structural modification of DHFR-inhibitory 2,4-diamino-6-(4-substituted benzylamino-3-nitrophenyl)-6-ethylpyrimidines ('benzoprims').

  Journal of medicinal chemistry 20040729

• Conventional adjuvant chemotherapy versus single-cycle, autograft-supported, high-dose, late-intensification chemotherapy in high-risk breast cancer patients: a randomized trial.

  Journal of the National Cancer Institute 20040721

• Reduced expression of small GTPases and hypermethylation of the folate binding protein gene in cisplatin-resistant cells.

  British journal of cancer 20040719

• Multiple sclerosis: management issues during pregnancy.

  European journal of obstetrics, gynecology, and reproductive biology 20040715

• How effective are the usual treatments for Crohn's disease?

  Alimentary pharmacology & therapeutics 20040715

• Clonal evolution as pathogenetic mechanism in relapse of primary CNS lymphoma.

  Neurology 20040713

• Direct determination of vibrational density of states change on ligand binding to a protein.

  Physical review letters 20040709

• Adsorption of methotrexate and calcium leucovorin onto cholestyramine in vitro.

  International journal of pharmaceutics 20040708

• Primary cardiac T-cell lymphoma.

  Annals of hematology 20040701

• Layered double hydroxide as an efficient drug reservoir for folate derivatives.

  Biomaterials 20040701

• Fever as a risk factor causing delayed elimination of methotrexate in pediatric patients receiving high doses of cancer chemotherapy.

  Cancer chemotherapy and pharmacology 20040701

• Assessment of biological prognostic factors provides clinically relevant information in patients with diffuse large B-cell lymphoma--a Nordic Lymphoma Group study.

  Annals of hematology 20040701

• Systemic treatment with either cyclosporin A or methotrexate does not influence the T helper 1/T helper 2 balance in psoriatic patients.

  Journal of clinical immunology 20040701

• High-dose methotrexate therapy of childhood acute lymphoblastic leukemia: lack of relation between serum methotrexate concentration and creatinine clearance.

  Pediatric blood & cancer 20040701

• Single nucleotide polymorphism profiling across the methotrexate pathway in normal subjects and patients with rheumatoid arthritis.

  Pharmacogenomics 20040701

• Neutropenic enterocolitis as a presenting complication of acute lymphoblastic leukemia: an unusual case marked by delayed perforation of the descending colon.

  Journal of pediatric surgery 20040701

• Disruption of AtMRP4, a guard cell plasma membrane ABCC-type ABC transporter, leads to deregulation of stomatal opening and increased drought susceptibility.

  The Plant journal : for cell and molecular biology 20040701

• Concurrent and adjuvant chemotherapy for nasopharyngeal carcinoma: a factorial study.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040701

• Giant cell arteritis in a patient taking etanercept and methotrexate.

  The Journal of rheumatology 20040701

• A novel CIAS1 mutation and plasma/cerebrospinal fluid cytokine profile in a German patient with neonatal-onset multisystem inflammatory disease responsive to methotrexate therapy.

  Pediatrics 20040701

• Intensive therapy for aggressive lymphoma.

  The New England journal of medicine 20040701

• Sulfasalazine is a potent inhibitor of the reduced folate carrier: implications for combination therapies with methotrexate in rheumatoid arthritis.

  Arthritis and rheumatism 20040701

• Medical methods for first-trimester abortion.

  American family physician 20040701

• Management of patients with metastatic gestational trophoblastic tumor.

  Gynecologic oncology 20040701

• Single-agent pulse dactinomycin has only modest activity for methotrexate-resistant gestational trophoblastic neoplasia.

  Gynecologic oncology 20040701

• Reported medication errors associated with methotrexate.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20040701

• Health-related quality of life in axillary node-negative, estrogen receptor-negative breast cancer patients undergoing AC versus CMF chemotherapy: findings from the National Surgical Adjuvant Breast and Bowel Project B-23.

  Breast cancer research and treatment 20040701

• [Salvianolic acid A inhibits nucleoside transport and potentiates the antitumor activity of chemotherapeutic drugs].

  Yao xue xue bao = Acta pharmaceutica Sinica 20040701

• Methotrexate induced accelerated nodulosis.

  The Journal of the Association of Physicians of India 20040701

• Trial of Atorvastatin in Rheumatoid Arthritis (TARA): double-blind, randomised placebo-controlled trial.

  Lancet (London, England) 20040619

• [Methotrexate combined with leflunomide or hydroxychloroquine in the treatment of rheumatoid arteritis].

  Zhonghua yi xue za zhi 20040617

• p14ARF expression increases dihydrofolate reductase degradation and paradoxically results in resistance to folate antagonists in cells with nonfunctional p53.

  Cancer research 20040615

• Use of neoadjuvant chemotherapy prior to radical hysterectomy in cervical cancer: monitoring tumour shrinkage and molecular profile on magnetic resonance and assessment of 3-year outcome.

  British journal of cancer 20040614

• [Diagnosis and therapy of rheumatoid arthritis].

  Deutsche medizinische Wochenschrift (1946) 20040604

• Methotrexate induces interleukin-8 production by human bronchial and alveolar epithelial cells.

  Clinical science (London, England : 1979) 20040601

• Mouse reduced in osteosclerosis transporter functions as an organic anion transporter 3 and is localized at abluminal membrane of blood-brain barrier.

  The Journal of pharmacology and experimental therapeutics 20040601

• Use of methotrexate-based peptide substrates to characterize the substrate specificity of prostate-specific membrane antigen (PSMA).

  Cancer biology & therapy 20040601

• Intra-articular methotrexate in knee synovitis.

  Rheumatology (Oxford, England) 20040601

• Relationship between myalgias/arthralgias occurring in patients receiving quinupristin/dalfopristin and biliary dysfunction.

  The Journal of antimicrobial chemotherapy 20040601

• Lipophilic conjugates of methotrexate with short-chain alkylamino acids as DHFR inhibitors. Synthesis, biological evaluation, and molecular modeling.

  Bioorganic & medicinal chemistry 20040601

• Primary non-Hodgkin's lymphoma of the CNS treated with CHOD/BVAM or BVAM chemotherapy before radiotherapy: long-term survival and prognostic factors.

  International journal of radiation oncology, biology, physics 20040601

• Differential attenuation of clavicle growth after asymmetric mantle radiotherapy.

  International journal of radiation oncology, biology, physics 20040601

• Prevalence and course of fatigue in breast cancer patients receiving adjuvant chemotherapy.

  Annals of oncology : official journal of the European Society for Medical Oncology 20040601

• Targeting prostate-specific membrane antigen in cancer therapy: can molecular medicine be brought to the surface?

  Cancer biology & therapy 20040601

• High-dose methotrexate and asparaginase for the treatment of children with acute lymphoblastic leukemia: why and how?

  Journal of pediatric hematology/oncology 20040601

• Effects of intraventricular methotrexate on folate, adenosine, and homocysteine metabolism in cerebrospinal fluid.

  Journal of pediatric hematology/oncology 20040601

• General principles of medical therapy of inflammatory bowel disease.

  Gastroenterology clinics of North America 20040601

• Galloping ophthalmoplegia and numb chin in Burkitt lymphoma.

  Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society 20040601

• Anterior uveitis in a child with Takayasu's arteritis.

  Clinical & experimental ophthalmology 20040601

• [A case of curatively resected gastric cancer through an effective response to chemotherapy].

  Gan to kagaku ryoho. Cancer & chemotherapy 20040601

• Influence of polymerization technique and experimental variables on the particle properties and release kinetics of methotrexate from poly(butylcyanoacrylate) nanoparticles.

  Acta pharmaceutica (Zagreb, Croatia) 20040601

• Salvage chemotherapy for high-risk gestational trophoblastic tumor.

  The Journal of reproductive medicine 20040601

• EMA/EP chemotherapy for chemorefractory gestational trophoblastic tumor.

  The Journal of reproductive medicine 20040601

• Phase II study of sequential methotrexate and 5-fluorouracil chemotherapy against peritoneally disseminated gastric cancer with malignant ascites: a report from the Gastrointestinal Oncology Study Group of the Japan Clinical Oncology Group, JCOG 9603 Trial.

  Japanese journal of clinical oncology 20040601

• Seeding of malignant renal tumor through a nephrostomy tract.

  Journal of the Chinese Medical Association : JCMA 20040601

• [Preparation and characterization of stearic acid-grafted chitosan oligosaccharide polymeric micelles].

  Yao xue xue bao = Acta pharmaceutica Sinica 20040601

• [Fatal pancytopenia and methotrexate-trimethoprim-sulfamethoxazole interaction].

  Harefuah 20040601

• The H(+)-dependent reduced folate carrier 1 of humans and the sodium-dependent methotrexate carrier-1 of the rat are orthologs.

  FEBS letters 20040521

• Gene expression profiling reveals multiple toxicity endpoints induced by hepatotoxicants.

  Mutation research 20040518

• Allogeneic bone marrow transplantation for children with acute myelocytic leukemia in first remission demonstrates a role for graft versus leukemia in the maintenance of disease-free survival.

  Blood 20040515

• High-dose methotrexate-induced nephrotoxicity in patients with osteosarcoma.

  Cancer 20040515

• Proteasomes begin ornithine decarboxylase digestion at the C terminus.

  The Journal of biological chemistry 20040514

• Tight binding ligand approach to oligosaccharide-grafted protein.

  Bioorganic & medicinal chemistry letters 20040503

• How aggressive should initial therapy for rheumatoid arthritis be? Factors associated with response to 'non-aggressive' DMARD treatment and perspective from a 2-yr open label trial.

  Rheumatology (Oxford, England) 20040501

• A novel reduced intensity regimen for allogeneic hematopoietic stem cell transplantation associated with a reduced incidence of graft-versus-host disease.

  Bone marrow transplantation 20040501

• Methotrexate differentially affects growth of suspension and adherent cells.

  The international journal of biochemistry & cell biology 20040501

• Effect of graft-versus-host disease on the outcome of bone marrow transplantation from an HLA-identical sibling donor using GVHD prophylaxis with cyclosporin A and methotrexate.

  Leukemia 20040501

• Intracellular IL-4/IFN-gamma producing peripheral T lymphocyte subsets in B cell non-Hodgkin's lymphoma patients.

  European journal of haematology 20040501

• Final results of a phase I and pharmacokinetic study of gamma-methylene-10-deazaaminopterin (MDAM) administered intravenously daily for five consecutive days in patients with solid tumors.

  Cancer chemotherapy and pharmacology 20040501

• Specific tumour localisation of a huA33 antibody--carboxypeptidase A conjugate and activation of methotrexate-phenylalanine.

  International journal of oncology 20040501

• A case of multiple keratoacanthoma centrifugum marginatum.

  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20040501

• Down-regulation and altered localization of gamma-catenin in cisplatin-resistant adenocarcinoma cells.

  Molecular pharmacology 20040501

• Sirolimus and tacrolimus without methotrexate as graft-versus-host disease prophylaxis after matched related donor peripheral blood stem cell transplantation.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20040501

• Clinical relevance of different sequencing of doxorubicin and cyclophosphamide, methotrexate, and Fluorouracil in operable breast cancer.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040501

• Economic evaluation of folate supplementation during methotrexate treatment in rheumatoid arthritis.

  The Journal of rheumatology 20040501

• Previous ectopic pregnancy as a predictor of failure of systemic methotrexate therapy.

  Fertility and sterility 20040501

• Pharmacogenetic determinants of outcome in acute lymphoblastic leukaemia.

  British journal of haematology 20040501

• Markers for type II collagen breakdown predict the effect of disease-modifying treatment on long-term radiographic progression in patients with rheumatoid arthritis.

  Arthritis and rheumatism 20040501

• [Primary intraocular lymphoma with unusual clinical presentation and poor outcome].

  Klinische Monatsblatter fur Augenheilkunde 20040501

• Fatal acute encephalomyelitis after a single dose of intrathecal methotrexate.

  Pharmacotherapy 20040501

• Complete abortion of a nonviable cervical pregnancy following methotrexate treatment.

  American journal of perinatology 20040501

• Bilateral ear swelling and cough. Relapsing polychondritis.

  Postgraduate medicine 20040501

• Leflunomide.

  Rheumatic diseases clinics of North America 20040501

• Preparation of recombinant alpha-thrombin: high-level expression of recombinant human prethrombin-2 and its activation by recombinant ecarin.

  Journal of biochemistry 20040501

• [Effects of different first dose calcium tetrahydro-folate on toxicity and side effects of large dose methotrexate treated standard risk group children with acute lymphoblastic leukemia].

  Zhonghua er ke za zhi = Chinese journal of pediatrics 20040501

• Rheumatoid arthritis: more aggressive approach improves outlook.

  Cleveland Clinic journal of medicine 20040501

• [GVHD].

  Nihon rinsho. Japanese journal of clinical medicine 20040501

• Osteosarcoma occurring in osteogenesis imperfecta.

  Virchows Archiv : an international journal of pathology 20040501

• [Bone marrow aplasia following dipyrone treatment in a patient with Crohn's disease receiving long-term methotrexate].

  Gastroenterologie clinique et biologique 20040501

• Inactivation of the Leishmania tarentolae pterin transporter (BT1) and reductase (PTR1) genes leads to viable parasites with changes in folate metabolism and hypersensitivity to the antifolate methotrexate.

  The Journal of biological chemistry 20040430

• Dual purpose: some cancer therapies used to treat autoimmune diseases.

  Journal of the National Cancer Institute 20040421

• Induced abortion: an overview for internists.

  Annals of internal medicine 20040420

• [Effect of methotrexate on the immune response in selected experimental models].

  Postepy higieny i medycyny doswiadczalnej (Online) 20040420

• High-dose methotrexate pharmacokinetics and outcome of children and young adults with osteosarcoma.

  Cancer 20040415

• The health assessment questionnaire (HAQ) is strongly predictive of good outcome in early diffuse scleroderma: results from an analysis of two randomized controlled trials in early diffuse scleroderma.

  Rheumatology (Oxford, England) 20040401

• The development of targeted chemotherapy for CNS lymphoma-a pilot study of the IDARAM regimen.

  Cancer chemotherapy and pharmacology 20040401

• Quantitative evaluation of the drug-drug interactions between methotrexate and nonsteroidal anti-inflammatory drugs in the renal uptake process based on the contribution of organic anion transporters and reduced folate carrier.

  The Journal of pharmacology and experimental therapeutics 20040401

• Does vitamin A prevent high-dose-methotrexate-induced D-xylose malabsorption in children with cancer?

  Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20040401

• Labeling of fusion proteins of O6-alkylguanine-DNA alkyltransferase with small molecules in vivo and in vitro.

  Methods (San Diego, Calif.) 20040401

• Interleukin 4 plasma levels in psoriasis vulgaris patients.

  Medical science monitor : international medical journal of experimental and clinical research 20040401

• A prospective study of concurrent cyclophosphamide/methotrexate/5-fluorouracil and reduced-dose radiotherapy in patients with early-stage breast carcinoma.

  Cancer 20040401

• Effects of morphine on methotrexate disposition in mice.

  Clinical and experimental pharmacology & physiology 20040401

• Tolerance of radiotherapy and chemotherapy in elderly patients with bladder cancer.

  American journal of clinical oncology 20040401

• A randomized controlled trial of colchicine plus ursodiol versus methotrexate plus ursodiol in primary biliary cirrhosis: ten-year results.

  Hepatology (Baltimore, Md.) 20040401

• Cogan syndrome in children: early diagnosis and treatment is critical to prognosis.

  American journal of ophthalmology 20040401

• Methylated metabolites of 6-mercaptopurine are associated with hepatotoxicity.

  Clinical pharmacology and therapeutics 20040401

• Tyrosine kinase inhibitors of the epidermal growth factor receptor as adjuncts to systemic chemotherapy for muscle-invasive bladder cancer.

  Urology 20040401

• Methotrexate and MX-68, a new derivative of methotrexate, limit infarct size via adenosine-dependent mechanisms in canine hearts.

  Journal of cardiovascular pharmacology 20040401

• Safety of rituximab therapy during the first trimester of pregnancy: a case history.

  European journal of haematology 20040401

• Gastroretentive delivery systems: hollow beads.

  Drug development and industrial pharmacy 20040401

• Fatal methotrexate-induced pneumonitis in a psoriatic patient.

  Military medicine 20040401

• Modified magrath regimens for adults with Burkitt and Burkitt-like lymphomas: preserved efficacy with decreased toxicity.

  Leukemia & lymphoma 20040401

• [A case of anaphylactic shock induced by pirarubicin hydrochloride].

  Hinyokika kiyo. Acta urologica Japonica 20040401

• [Active chemotherapy with gemcitabine, carboplatin and docetaxel for three patients with MVAC-resistant liver metastasis of urothelial carcinoma].

  Hinyokika kiyo. Acta urologica Japonica 20040401

• Leflunomide in the treatment of rheumatoid arthritis.

  Clinical therapeutics 20040401

• The analysis of correlations between drug resistance and clinical/laboratory measures found in a group of children with all treated by ALL-BFM 90 protocol.

  Bulletin du cancer 20040401

• Identification of proline residues in the core cytoplasmic and transmembrane regions of multidrug resistance protein 1 (MRP1/ABCC1) important for transport function, substrate specificity, and nucleotide interactions.

  The Journal of biological chemistry 20040326

• Reversed-phase high-performance liquid chromatography of polar lipids. II. Procedure for a phospholipid derivative of methotrexate.

  Journal of chromatography. A 20040326

• Initial treatment of aggressive lymphoma with high-dose chemotherapy and autologous stem-cell support.

  The New England journal of medicine 20040325

• Methotrexate conjugates: a molecular in vivo protein tag.

  Angewandte Chemie (International ed. in English) 20040319

• Relation between the duration of remission and hyperglycemia during induction chemotherapy for acute lymphocytic leukemia with a hyperfractionated cyclophosphamide, vincristine, doxorubicin, and dexamethasone/methotrexate-cytarabine regimen.

  Cancer 20040315

• Primary cultures of microglial cells for testing toxicity of anticancer drugs.

  Toxicology letters 20040314

• Cloning, expression, and characterization of Mycobacterium tuberculosis dihydrofolate reductase.

  FEMS microbiology letters 20040312

• [Collagen diseases and rheumatic diseases].

  Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20040310

• Wegener's granulomatosis of the prostate gland.

  Rheumatology international 20040301

• Sodium-dependent methotrexate carrier-1 is expressed in rat kidney: cloning and functional characterization.

  American journal of physiology. Renal physiology 20040301

• Insulin-induced enhancement of antitumoral response to methotrexate in breast cancer patients.

  Cancer chemotherapy and pharmacology 20040301

• Using loco-regional recurrence as an indicator of the quality of breast cancer treatment.

  European journal of cancer (Oxford, England : 1990) 20040301

• Combined intravenous methotrexate and cyclophosphamide for refractory childhood lupus nephritis.

  Annals of the rheumatic diseases 20040301

• Folate supplementation and methotrexate treatment in rheumatoid arthritis: a review.

  Rheumatology (Oxford, England) 20040301

• The effect of the steroid-sparing response to low-dose methotrexate on bone metabolism in glucocorticoid-dependent asthmatics.

  Clinica chimica acta; international journal of clinical chemistry 20040301

• Optimal management of methotrexate intoxication in a child with osteosarcoma.

  The Annals of pharmacotherapy 20040301

• Drug-induced liver injury.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20040301

• Quinoxaline chemistry. Part XVII. Methyl [4-(substituted 2-quinoxalinyloxy) phenyl] acetates and ethyl N-([4-(substituted 2-quinoxalinyloxy) phenyl] acetyl) glutamates analogs of methotrexate: synthesis and evaluation of in vitro anticancer activity.

  Farmaco (Societa chimica italiana : 1989) 20040301

• Combination therapy to treat moderate to severe psoriasis.

  Journal of the American Academy of Dermatology 20040301

• Recovering the true targets of specific ligands by virtual screening of the protein data bank.

  Proteins 20040301

• Severe complications after intrathecal methotrexate (MTX) for treatment of primary central nervous system lymphoma (PCNSL).

  Clinical neurology and neurosurgery 20040301

• Atypical Cogan's syndrome presenting with bilateral acute glaucoma.

  Eye (London, England) 20040301

• Emergency treatment of life-threatening intrathecal methotrexate overdose.

  Neurotoxicology 20040301

• Granulocytic sarcoma of the testis.

  Urology 20040301

• Neoadjuvant cisplatinum based combination chemotherapy in patients with invasive bladder cancer: a combined analysis of two Nordic studies.

  European urology 20040301

• [A case of advanced gastric cancer with DIC treated by sequential MTX and 5-FU].

  Gan to kagaku ryoho. Cancer & chemotherapy 20040301

• [Two cases of breast cancer markedly responded to neoadjuvant chemoendocrine therapy (2 cycles of CMF and tamoxifen, pCR and near pCR)].

  Gan to kagaku ryoho. Cancer & chemotherapy 20040301

• Differential mucin expression in colon carcinoma HT-29 clones with variable resistance to 5-fluorouracil and methotrexate.

  Biology of the cell 20040301

• Ten-year radiographic outcome in patients with rheumatoid factor positive rheumatoid arthritis treated with aggressive immunosuppressive combination therapy.

  The Journal of rheumatology. Supplement 20040301

• Infiltrative lung disease due to noncytotoxic agents.

  Clinics in chest medicine 20040301

• Chemotherapy-induced lung disease.

  Clinics in chest medicine 20040301

• Drug-induced pleural disease.

  Clinics in chest medicine 20040301

• Drug-induced pulmonary infection.

  Clinics in chest medicine 20040301

• [Reduced intensity stem cell transplantation for metastatic renal cell carcinoma].

  Nihon Hinyokika Gakkai zasshi. The japanese journal of urology 20040301

• Intrahepatic arterial administration of low-dose methotrexate in patients with severe hepatic graft-versus-host disease: an open-label, uncontrolled trial.

  Clinical therapeutics 20040301

• Defining the appropriate dosage of folinic acid after high-dose methotrexate for childhood acute lymphatic leukemia that will prevent neurotoxicity without rescuing malignant cells in the central nervous system.

  Journal of pediatric hematology/oncology 20040301

• Leflunomide for chronic sarcoidosis.

  Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG 20040301

• Lactoferrin reduces methotrexate-induced small intestinal damage, possibly through inhibition of GLP-2-mediated epithelial cell proliferation.

  Digestive diseases and sciences 20040301

• Induction of a multifactorial resistance phenotype by high paclitaxel selective pressure in a human ovarian carcinoma cell line.

  Journal of experimental & clinical cancer research : CR 20040301

• Pharmacogenetics and inflammatory bowel disease: progress and prospects.

  Inflammatory bowel diseases 20040301

• Therapeutic effect of the combination of etanercept and methotrexate compared with each treatment alone in patients with rheumatoid arthritis: double-blind randomised controlled trial.

  Lancet (London, England) 20040227

• Cognitive status and quality of life after treatment for primary CNS lymphoma.

  Neurology 20040224

• Cell cycle activation linked to neuronal cell death initiated by DNA damage.

  Neuron 20040219

• 20S proteasome mediated degradation of DHFR: implications in neurodegenerative disorders.

  Archives of biochemistry and biophysics 20040215

• Intensive sequential chemotherapy with hematopoietic growth factor support for non-Hodgkin lymphoma in patients infected with the human immunodeficiency virus.

  Cancer 20040215

• Reduced folate carrier mutations are not the mechanism underlying methotrexate resistance in childhood acute lymphoblastic leukemia.

  Cancer 20040215

• Monitoring methotrexate-induced hepatic fibrosis in patients with psoriasis: are serial liver biopsies justified?

  Alimentary pharmacology & therapeutics 20040215

• [Treatment with methotrexate in a patient with subglottic stenosis as initial manifestation of limited Wegener granulomatosis].

  Medicina clinica 20040214

• Treatment-induced leukoencephalopathy in primary CNS lymphoma: a clinical and autopsy study.

  Neurology 20040210

• Outcome of flat bone sarcomas (other than Ewing's) in children and adolescents: a study of 25 cases.

  British journal of cancer 20040209

• A survey of British rheumatologists' DMARD preferences for rheumatoid arthritis.

  Rheumatology (Oxford, England) 20040201

• Multidrug resistance protein 4 (MRP4/ABCC4) mediates efflux of bimane-glutathione.

  The international journal of biochemistry & cell biology 20040201

• Role of curcumin and the inhibition of NF-kappaB in the onset of chemotherapy-induced mucosal barrier injury.

  Leukemia 20040201

• Feasibility of central co-ordinated EMA/CO for gestational trophoblastic disease in the Netherlands.

  BJOG : an international journal of obstetrics and gynaecology 20040201

• Methotrexate eluting stents: to modify or cure?

  Heart (British Cardiac Society) 20040201

• Treatment of intracranial rat glioma model with implant of radiosensitizer and biomodulator drug combined with external beam radiotherapy.

  International journal of radiation oncology, biology, physics 20040201

• Adjuvant chemotherapy in elderly patients with breast cancer: a survey of the Breast International Group (BIG).

  Annals of oncology : official journal of the European Society for Medical Oncology 20040201

• The management and survival of patients with advanced germ-cell tumours: improving outcome in intermediate and poor prognosis patients.

  Clinical oncology (Royal College of Radiologists (Great Britain)) 20040201

• Reduced full-field electroretinogram (ERG) in a patient treated with methotrexate.

  Acta ophthalmologica Scandinavica 20040201

• Reversible posterior leucoencephalopathy during oral treatment with methotrexate.

  Journal of neurology 20040201

• [Adjuvant chemotherapy for breast cancer--a current controversy].

  Gan to kagaku ryoho. Cancer & chemotherapy 20040201

• Malignant lymphoma associated with rheumatoid arthritis, developing shortly after initiation of oral methotrexate.

  Internal medicine (Tokyo, Japan) 20040201

• Effect of MX-68 on airway inflammation and hyperresponsiveness in mice and guinea-pigs.

  The Journal of pharmacy and pharmacology 20040201

• [Observation on treatment of post-remission acute myeloid leukemia patients by lingxiong piaoling powder and longchan cigu decoction].

  Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20040201

• Intravenous methotrexate for treatment of interstitial pregnancy: a case report.

  The Journal of reproductive medicine 20040201

• Treating immunobullous diseases: an update.

  Dermatology nursing 20040201

• [Radiation and concomitant chemotherapy after surgery for breast cancer].

  Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique 20040201

• [Sequencing of adjuvant treatment after surgery for invasive breast cancer].

  Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique 20040201

• [Signet ring cell carcinoma of the urinary bladder: a case report].

  Hinyokika kiyo. Acta urologica Japonica 20040201

• Isolated central nervous system relapse in lymphoid blast crisis chronic myeloid leukemia and acute lymphoblastic leukemia in patients on imatinib therapy.

  Leukemia & lymphoma 20040201

• [Methotrexate use in patients with systemic lupus erythematosus].

  Revista medica de Chile 20040201

• Area under the curve of methotrexate and creatinine clearance are outcome-determining factors in primary CNS lymphomas.

  British journal of cancer 20040126

• Primary mediastinal large B-cell lymphoma (PMLBCL): long-term results from a retrospective multicentre Italian experience in 138 patients treated with CHOP or MACOP-B/VACOP-B.

  British journal of cancer 20040126

• Improved survival in patients with peritoneal metastases from colorectal cancer: a preliminary study.

  British journal of cancer 20040126

• Effect of the methylenetetrahydrofolate reductase C677T polymorphism on chemosensitivity of colon and breast cancer cells to 5-fluorouracil and methotrexate.

  Journal of the National Cancer Institute 20040121

• Docetaxel and cisplatin with granulocyte colony-stimulating factor (G-CSF) versus MVAC with G-CSF in advanced urothelial carcinoma: a multicenter, randomized, phase III study from the Hellenic Cooperative Oncology Group.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040115

• A prominent low-pH methotrexate transport activity in human solid tumors: contribution to the preservation of methotrexate pharmacologic activity in HeLa cells lacking the reduced folate carrier.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20040115

• Interleukin-12 enhances the sensitivity of human osteosarcoma cells to 4-hydroperoxycyclophosphamide by a mechanism involving the Fas/Fas-ligand pathway.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20040115

• [Malignant rheumatoid arthritis in the young with polyneuritis as an initial symptom].

  Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20040110

• Heat shock protein 72 binds and protects dihydrofolate reductase against oxidative injury.

  Biochemical and biophysical research communications 20040102

• Three cycles of adriamycin, bleomycin, vinblastine, and dacarbazine (ABVD) or epirubicin, bleomycin, vinblastine, and methotrexate (EBVM) plus extended field radiation therapy in early and intermediate Hodgkin disease: 10-year results of a randomized trial.

  Blood 20040101

• Bone marrow stroma damage induced by chemotherapy for acute lymphoblastic leukemia in children.

  Pediatric research 20040101

• Successful salvage therapy of resistant gestational trophoblastic disease with etoposide, methotrexate, actinomycin-D, etoposide, cisplatin (EMA/EP).

  Archives of gynecology and obstetrics 20040101

• Expression of thymidylate synthase, thymidine phosphorylase, dihydropyrimidine dehydrogenase, E2F-1, Bak, Bcl-X, and Bcl-2, and clinical outcomes for gastric cancer patients treated with bolus 5-fluorouracil.

  Oncology reports 20040101

• Antibody-directed enzyme-prodrug therapy.

  Methods in molecular medicine 20040101

• Hemostatic side effects of high-dose methotrexate in childhood acute lymphoblastic leukemia.

  Pediatric hematology and oncology 20040101

• Rheumatologic manifestations of sarcoidosis.

  Current opinion in rheumatology 20040101

• Successful treatment without cranial radiotherapy of children receiving intensified chemotherapy for acute lymphoblastic leukaemia: results of the risk-stratified randomized central nervous system treatment trial MRC UKALL XI (ISRC TN 16757172).

  British journal of haematology 20040101

• Analysis of dihydrofolate reductase and reduced folate carrier gene status in relation to methotrexate resistance in osteosarcoma cells.

  Annals of oncology : official journal of the European Society for Medical Oncology 20040101

• Vinorelbine, methotrexate and fluorouracil (VMF) as first-line therapy in metastatic breast cancer: significance of the time between initiation of adjuvant therapy and of therapy for metastatic breast cancer.

  Annals of oncology : official journal of the European Society for Medical Oncology 20040101

• Platinum-free combination chemotherapy in patients with advanced or metastatic transitional cell carcinoma.

  Cancer 20040101

• Problems with nomenclature and pharmacodynamics in trophoblastic disease.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040101

• Combined standard graft-versus-host disease (GvHD) prophylaxis with mycophenolate mofetil (MMF) in allogeneic peripheral blood stem cell transplantation from unrelated donors.

  Bone marrow transplantation 20040101

• Periaortitis: gadolinium-enhanced magnetic resonance imaging and response to therapy in four patients.

  Annals of vascular surgery 20040101

• Significance of mismatch repair protein expression in the chemotherapeutic response of sporadic invasive ductal carcinoma of the breast.

  The breast journal 20040101

• Adherence to the guidelines of the CCCE in the treatment of node-positive breast cancer patients.

  European journal of cancer (Oxford, England : 1990) 20040101

• Impact of initial aggressive drug treatment with a combination of disease-modifying antirheumatic drugs on the development of work disability in early rheumatoid arthritis: a five-year randomized followup trial.

  Arthritis and rheumatism 20040101

• Capillary leak syndrome induced by acitretin.

  The British journal of dermatology 20040101

• Outcome of children with high-risk acute lymphoblastic leukemia (HR-ALL): Nordic results on an intensive regimen with restricted central nervous system irradiation.

  Pediatric blood & cancer 20040101

• Methotrexate pharmacokinetics and survival in osteosarcoma.

  Pediatric blood & cancer 20040101

• Novel magnetic supports for small molecule affinity capture of proteins for use in proteomics.

  Molecular diversity 20040101

• Medical methods for first trimester abortion.

  The Cochrane database of systematic reviews 20040101

• Antiproliferative efficacy of the third-generation bisphosphonate, zoledronic acid, combined with other anticancer drugs in leukemic cell lines.

  International journal of hematology 20040101

• Intestinal barrier function and secretion in methotrexate-induced rat intestinal mucositis.

  Digestive diseases and sciences 20040101

• Fatigue, weight gain, lethargy and amenorrhea in breast cancer patients on chemotherapy: is subclinical hypothyroidism the culprit?

  Breast cancer research and treatment 20040101

• A childhood cavernous conundrum.

  Survey of ophthalmology 20040101

• Lymphomatoid papulosis associated with recurrent cutaneous T-cell lymphoma.

  Annals of the Academy of Medicine, Singapore 20040101

• [Disseminated necrotizing leukoencephalopathy].

  Nihon rinsho. Japanese journal of clinical medicine 20040101

• [A case of polymyalgia rheumatica with improved steroid-responsibility after discontinuing carbamazepine].

  No to shinkei = Brain and nerve 20040101

• Synovial sarcoma after chemotherapy for osteosarcoma: a case report.

  Clinical orthopaedics and related research 20040101

• The results of treatment with idarubicin in childhood acute nonlymphoblastic leukemia.

  The Turkish journal of pediatrics 20040101

• Infliximab-induced lupus or rheumatoid arthritis (RA) overlapping with systemic lupus erythematosus (SLE) unmasked by infliximab.

  Clinical and experimental rheumatology 20040101

• Recent translational research: antiangiogenic therapy for breast cancer - where do we stand?

  Breast cancer research : BCR 20040101

• Hypoxia-inducible factor 1 alpha in high-risk breast cancer: an independent prognostic parameter?

  Breast cancer research : BCR 20040101

• EMA-EP regimen, as firstline multiple agent chemotherapy in high-risk GTT patients (stage II-IV).

  International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20040101

• Medical methods for first trimester abortion.

  The Cochrane database of systematic reviews 20040101

• Colchicine for primary biliary cirrhosis.

  The Cochrane database of systematic reviews 20040101

• Amelioration of methotrexate-induced enteritis by melatonin in rats.

  Cell biochemistry and function 20040101

• Methotrexate-induced leukoencephalopathy reversed by aminophylline and high-dose folinic acid.

  Acta haematologica 20040101

• Dehydropyrimidine dehydrogenase deficiency in a cancer patient undergoing 5-fluorouracil chemotherapy.

  Anticancer research 20040101

• The standardised mistletoe extract PS76A2 improves QoL in patients with breast cancer receiving adjuvant CMF chemotherapy: a randomised, placebo-controlled, double-blind, multicentre clinical trial.

  Anticancer research 20040101

• Local recurrence in breast cancer after conservative surgery: timing of radiotherapy and sequencing of chemotherapy.

  Anticancer research 20040101

• Enter Alimta: a new generation antifolate.

  The oncologist 20040101

• Leflunomide-associated pancytopenia with or without methotrexate.

  The Annals of pharmacotherapy 20040101

• [Breast cancer adjuvants: results of a DUR (drug utilization research) study].

  I supplementi di Tumori : official journal of Societa italiana di cancerologia ... [et al.] 20040101

• Deactivation of endothelium and reduction in angiogenesis in psoriatic skin and synovium by low dose infliximab therapy in combination with stable methotrexate therapy: a prospective single-centre study.

  Arthritis research & therapy 20040101

• [Markov model of decision making for basic therapy of rheumatoid arthritis: oder of monotherapy and expenses for drug therapy].

  Terapevticheskii arkhiv 20040101

• [Tubal pregnancy treated with oral methotrexate. Report of one case].

  Ginecologia y obstetricia de Mexico 20040101

• Treatment of dermatomyositis and polymyositis with anti-tumor necrosis factor-alpha: long-term follow-up.

  European neurology 20040101

• Mutation and accumulation of p53 related to results of adjuvant therapy of postmenopausal breast cancer patients.

  Acta oncologica (Stockholm, Sweden) 20040101

• A case of L-dopa-responsive parkinsonian syndrome after low-dose oral methotrexate intake.

  Clinical neuropharmacology 20040101

• Synthesis and characterization of dextran-peptide-methotrexate conjugates for tumor targeting via mediation by matrix metalloproteinase II and matrix metalloproteinase IX.

  Bioconjugate chemistry 20040101

• Methotrexate for ankylosing spondylitis.

  The Cochrane database of systematic reviews 20040101

• Efficacy of infusional biomodulated 5-fluorouracil in metastatic colorectal cancer after raltitrexed failure.

  Anticancer research 20040101

• Renal function in rheumatoid arthritis patients treated with methotrexate and infliximab.

  Clinical and experimental rheumatology 20040101

• [Treatment of Wegener's granulomatosis].

  Reumatismo 20040101

• Design and development of new combinations of the CMF agents with taxanes (paclitaxel or docetaxel) in advanced breast cancer: a feasibility study.

  Tumori 20040101

• Interstitial lung disease induced by drugs and radiation.

  Respiration; international review of thoracic diseases 20040101

• Effective knock down of very high ABCG2 expression by a hammerhead ribozyme.

  Anticancer research 20040101

• Failure of alkylating agents to improve induction chemotherapy of oropharyngeal squamous cell cancer.

  Anticancer research 20040101

• Evaluation and management of brain metastatic patients with high-risk gestational trophoblastic tumors.

  International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20040101

• Doppler study of myometrium in invasive gestational trophoblastic disease.

  International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20040101

• Immunohistochemical investigations and introduction of new therapeutic strategies in scleromyxoedema: case report.

  BMC dermatology 20040101

• Nasal-type NK/T-cell lymphoma successfully treated with ProMACE-CytaBOM therapy.

  Dermatology (Basel, Switzerland) 20040101

• Effect of vitamin A against methotrexate-induced damage to the small intestine in rats.

  Medical principles and practice : international journal of the Kuwait University, Health Science Centre 20040101

• [The treatment of recurrent uveitis with TNF-alpha inhibitors].

  Reumatismo 20040101

• All-transretinoic acid and chemotherapy in the treatment of acute promyelocytic leukemia.

  Indian journal of cancer 20040101

• [Managing methotrexate toxicity: a case report].

  Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20040101

• Effect of primary anthracycline-based chemotherapy on disseminated tumor cells in locally advanced breast cancer.

  Anticancer research 20040101

• Methotrexate as a photosensitiser.

  Anticancer research 20040101

• Infliximab therapy in rheumatoid arthritis and ankylosing spondylitis-induced specific antinuclear and antiphospholipid autoantibodies without autoimmune clinical manifestations: a two-year prospective study.

  Arthritis research & therapy 20040101

• [Effect of small-dose glucocorticoids on the course of early rheumatic arthritis].

  Klinicheskaia meditsina 20040101

• Evidence-based evaluation of immunomodulatory therapy for the cutaneous manifestations of lupus.

  Advances in dermatology 20040101

• [The effect of antitumor polychemotherapy on the structural, metabolic, and functional status of erythrocytes in patients with head and neck tumors].

  Eksperimental'naia i klinicheskaia farmakologiia 20040101

• Gemcitabine-induced apoptosis in a drug-resistant mouse leukemia L1210 cell line that does not express p53.

  Advances in enzyme regulation 20040101

• [Synthesis of a lipid derivative of the antitumor agent methotrexate].

  Bioorganicheskaia khimiia 20040101

• [Immunologic monitoring in children with acute lymphoblastic leukemia during maintenance treatment with regard to co-existing infections].

  Wiadomosci lekarskie (Warsaw, Poland : 1960) 20040101

• Patterns of weight and body composition change in premenopausal women with early stage breast cancer: has weight gain been overestimated?

  Cancer nursing 20040101

• Induction of autoantibodies in refractory rheumatoid arthritis treated by infliximab.

  Clinical and experimental rheumatology 20040101

• Combination therapies in spondyloarthropathies.

  The Kobe journal of medical sciences 20040101

• [Febrile neutropenia in patients with breast cancer submitted to chemotherapy: a 12-year experience].

  Revista da Associacao Medica Brasileira (1992) 20040101

• Localized nodular vasculitis: a new variant of localized cutaneous polyarteritis nodosa?

  Clinical and experimental rheumatology 20040101

• Churg Strauss syndrome--successful induction of remission with methotrexate and unexpected high cardiac and pulmonary relapse ratio during maintenance treatment.

  Clinical and experimental rheumatology 20040101

• [Treatment results in children with standard-risk acute lymphoblastic leukemia. Report of the Polish Pediatric Leukemia/Lymphoma Study Group].

  Przeglad lekarski 20040101

• Preliminary individual adjuvant chemotherapy for primary central nervous system lymphomas based on the expression of drug-resistance genes.

  Brain tumor pathology 20040101

• [Diagnostic significance of reticulocyte analysis by flow cytometry, in children with acute lymphoblastic leukaemia (ALL) on chemotherapy].

  Medycyna wieku rozwojowego 20040101

• Therapeutic potential of 5-[125I]iodo-2'-deoxyuridine and methotrexate in the treatment of advanced neoplastic meningitis.

  International journal of radiation biology 20040101

• Clinical and radiological disease-course in a Swedish DMARD-treated early RA-inception cohort: an observational study.

  Scandinavian journal of rheumatology 20040101

• [Autoimmune urticaria. Treatment with methotrexate].

  Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993) 20040101

• Successful treatment of multicentric reticulohistiocytosis with a combination of infliximab, prednisolone and methotrexate.

  Acta dermato-venereologica 20040101

• Clostridium difficile toxin assay in psoriatic patients.

  Tropical gastroenterology : official journal of the Digestive Diseases Foundation 20040101

• Reduction of drug toxicity using dendrimers based on melamine.

  Molecular pharmaceutics 20040101

• Cellular uptake of Clostridium botulinum C2 toxin: membrane translocation of a fusion toxin requires unfolding of its dihydrofolate reductase domain.

  Biochemistry 20031230

• Methylenetetrahydrofolate reductase C677T polymorphism and toxicity in allogeneic hematopoietic cell transplantation.

  Transplantation 20031227

• A new and efficient synthesis of pyrrolo[2,3-d]pyrimidine anticancer agents: Alimta (LY231514, MTA), homo-Alimta, TNP-351, and some aryl 5-substituted pyrrolo[2,3-d]pyrimidines.

  The Journal of organic chemistry 20031226

• Ovarian ablation as adjuvant therapy for premenopausal women with breast cancer--another step forward.

  Journal of the National Cancer Institute 20031217

• Adjuvant chemotherapy followed by goserelin versus either modality alone for premenopausal lymph node-negative breast cancer: a randomized trial.

  Journal of the National Cancer Institute 20031217

• High-dose methotrexate-based chemotherapy followed by consolidating radiotherapy in non-AIDS-related primary central nervous system lymphoma: European Organization for Research and Treatment of Cancer Lymphoma Group Phase II Trial 20962.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20031215

• Primary central nervous system lymphoma: results of a pilot and phase II study of systemic and intraventricular chemotherapy with deferred radiotherapy.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20031215

• Reversible ovarian ablation or chemotherapy: are we ready for quality of life to guide adjuvant treatment decisions in breast cancer?

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20031215

• Quality of life in goserelin-treated versus cyclophosphamide + methotrexate + fluorouracil-treated premenopausal and perimenopausal patients with node-positive, early breast cancer: the Zoladex Early Breast Cancer Research Association Trialists Group.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20031215

• Incidence and predictors of low dose-intensity in adjuvant breast cancer chemotherapy: a nationwide study of community practices.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20031215

• Is surgery necessary after complete clinical remission following neoadjuvant chemotherapy for early breast cancer?

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20031215

• Preoperative therapy versus immediate surgery in nonmetastatic osteosarcoma.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20031215

• Hepatitis C and methotrexate.

  Arthritis and rheumatism 20031215

• Low-risk persistent gestational trophoblastic disease treated with low-dose methotrexate: efficacy, acute and long-term effects.

  British journal of cancer 20031215

• Induced protein dimerization in vivo through covalent labeling.

  Journal of the American Chemical Society 20031210

• Radiographic progression in early rheumatoid arthritis: a 12-month randomized controlled study comparing the combination of cyclosporin and methotrexate with methotrexate alone.

  Rheumatology (Oxford, England) 20031201

• Bone mineral density in premenopausal women treated for node-positive early breast cancer with 2 years of goserelin or 6 months of cyclophosphamide, methotrexate and 5-fluorouracil (CMF).

  Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20031201

• White matter and cerebral metabolite changes in children undergoing treatment for acute lymphoblastic leukemia: longitudinal study with MR imaging and 1H MR spectroscopy.

  Radiology 20031201

• Progression of osteosarcoma after high-dose methotrexate: over-rescue by folinic acid.

  Pediatric hematology and oncology 20031201

• Alkylglycerol opening of the blood-brain barrier to small and large fluorescence markers in normal and C6 glioma-bearing rats and isolated rat brain capillaries.

  British journal of pharmacology 20031201

• Disseminated tuberculosis, pulmonary aspergillosis and cutaneous herpes simplex infection in a patient with infliximab and methotrexate.

  Intensive care medicine 20031201

• Lectinocytochemical detection of apoptotic murine leukemia L1210 cells.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20031201

• Role of macrophages and stellate cells in the pathogenesis of veno-occlusive disease: an electron microscopic case study.

  Experimental and molecular pathology 20031201

• Novel therapies in pediatric rheumatic diseases.

  Current opinion in pediatrics 20031201

• Molecular characterization of human and rat organic anion transporter OATP-D.

  American journal of physiology. Renal physiology 20031201

• Pegylated asparaginase in combination with high-dose methotrexate for consolidation in adult acute lymphoblastic leukaemia in first remission: a pilot study.

  British journal of haematology 20031201

• [Standard and experimental therapy of cutaneous T-cell lymphoma].

  Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20031201

• Vinblastine, bleomycin, and methotrexate chemotherapy plus irradiation for patients with early-stage, favorable Hodgkin lymphoma: the experience of the Gruppo Italiano Studio Linfomi.

  Cancer 20031201

• Population pharmacokinetics of hydroxychloroquine in patients with rheumatoid arthritis.

  Therapeutic drug monitoring 20031201

• Differences and similarities among expert opinions on the diagnosis and treatment of pemphigus vulgaris.

  Journal of the American Academy of Dermatology 20031201

• Febrile ulceronecrotic Mucha-Habermann's disease managed with methylprednisolone semipulse and subsequent methotrexate therapies.

  Journal of the American Academy of Dermatology 20031201

• High incidence of hepatotoxicity of isoniazid treatment for tuberculosis chemoprophylaxis in patients with rheumatoid arthritis treated with methotrexate or sulfasalazine and anti-tumour necrosis factor inhibitors.

  Annals of the rheumatic diseases 20031201

• Graft-versus-lymphoma effect of donor lymphocyte infusion in indolent lymphomas relapsed after allogeneic stem cell transplantation.

  Bone marrow transplantation 20031201

• [Drug therapy of rheumatoid arthritis].

  Der Orthopade 20031201

• Efficient protection from methotrexate toxicity and selection of transduced human hematopoietic cells following gene transfer of dihydrofolate reductase mutants.

  Experimental hematology 20031201

• Severe lactic acidosis due to thiamine deficiency in a patient with B-cell leukemia/lymphoma on total parenteral nutrition during high-dose methotrexate therapy.

  Journal of pediatric hematology/oncology 20031201

• Treatment of high-risk gestational trophoblastic neoplasia with etoposide, methotrexate, actinomycin D, cyclophosphamide, and vincristine chemotherapy.

  Gynecologic oncology 20031201

• A pilot study of CODOX-M/IVAC in primary refractory or relapsed high-grade non-Hodgkin's lymphoma. A Scotland and Newcastle Lymphoma Group Study.

  Haematologica 20031201

• Cardiac lymphoma successfully treated with high dose chemotherapy followed by autologous haematopoietic stem cell transplantation.

  Haematologica 20031201

• [Immunomodulation in penetrating keratoplasty. Current status and perspectives].

  Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 20031201

• Effect of a drug combination treatment on ocular perfusion in recurrent idiopathic intermediate uveitis.

  Ocular immunology and inflammation 20031201

• Extranodal lymphoma originating from mucosa-associated lymphoid tissue of the nasopharynx.

  Acta oto-laryngologica 20031201

• Cervical hydatidiform molar pregnancy.

  The Australian & New Zealand journal of obstetrics & gynaecology 20031201

• Association of intestinal malignant lymphoma and ulcerative colitis.

  Internal medicine (Tokyo, Japan) 20031201

• Severe relapsing polychondritis occurring after ear piercing.

  The Journal of rheumatology 20031201

• Intractable pain in a rheumatoid wrist.

  The Journal of rheumatology 20031201

• A case of edematous dermatomyositis.

  The Journal of rheumatology 20031201

• Linear scleroderma en coup de sabre and brain calcification: is there a pathogenic relationship?

  The Journal of rheumatology 20031201

• [Efficacy and side effects of methotrexate in the treatment of ectopic pregnancy].

  Zhonghua fu chan ke za zhi 20031201

• Effect of ketoprofen and its enantiomers on the renal disposition of methotrexate in the isolated perfused rat kidney.

  The Journal of pharmacy and pharmacology 20031201

• Intravitreal methotrexate injections for intraocular involvement in primary central nervous system lymphoma.

  Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 20031201

• Comparison of intrathecal chemotherapy for leptomeningeal carcinomatosis of a solid tumor: methotrexate alone versus methotrexate in combination with cytosine arabinoside and hydrocortisone.

  Japanese journal of clinical oncology 20031201

• Effect of methotrexate and folinic acid on skeletal growth in mice.

  Acta paediatrica (Oslo, Norway : 1992) 20031201

• [A case report of a young patient with invasive bladder cancer].

  Hinyokika kiyo. Acta urologica Japonica 20031201

• Behçet's disease with relapsing cutaneous polyarteritis-nodosa-like lesions, responsive to oral cyclosporine therapy.

  Dermatology online journal 20031201

• Simultaneous determination of L- and D-methotrexate using a sequential injection analysis/amperometric biosensors system.

  Biosensors & bioelectronics 20031130

• High-level expression of full-length antibodies using trans-complementing expression vectors.

  Biotechnology and bioengineering 20031120

• Moderate neutropenia with adjuvant CMF confers improved survival in early breast cancer.

  British journal of cancer 20031117

• Infertility rates following POMB/ACE chemotherapy for male and female germ cell tumours - a retrospective long-term follow-up study.

  British journal of cancer 20031117

• Methotrexate/misoprostol embryopathy: report of four cases resulting from failed medical abortion.

  American journal of medical genetics. Part A 20031115

• Intensive methotrexate and cytarabine followed by high-dose chemotherapy with autologous stem-cell rescue in patients with newly diagnosed primary CNS lymphoma: an intent-to-treat analysis.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20031115

• Uncommon hematologic malignancies. Case 3. Parotid swelling during treatment for transformed mycosis fungoides.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20031115

• A substructure approach toward polymeric receptors targeting dihydrofolate reductase inhibitors. 2. Molecularly imprinted polymers against Z-l-glutamic acid showing affinity for larger molecules.

  The Journal of organic chemistry 20031114

• [Wegener's granulomatosis (morbus Wegener)].

  Praxis 20031112

• Lymph nodes in the irradiated field influence the yield of radiation-induced chromosomal aberrations in lymphocytes from breast cancer patients.

  International journal of radiation oncology, biology, physics 20031101

• Thymidine rescue: an antidote for pemetrexed-related toxicity in the setting of acute renal failure.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20031101

• Cyclosporin A in rheumatoid arthritis.

  Annals of the rheumatic diseases 20031101

• Cyclosporin and methotrexate therapy.

  Annals of the rheumatic diseases 20031101

• Reduced folate carrier protein expression in osteosarcoma: implications for the prediction of tumor chemosensitivity.

  Cancer 20031101

• Protein expression of the glucocorticoid receptor in childhood acute lymphoblastic leukemia.

  Haematologica 20031101

• Comparison of rheumatoid arthritis clinical trial outcome measures: a simulation study.

  Arthritis and rheumatism 20031101

• Prognostic factors in a large cohort of patients with early undifferentiated inflammatory arthritis after application of a structured management protocol.

  Arthritis and rheumatism 20031101

• [Quadruple therapy with CsA, MTX, MMF and ATG for preventing graft-versus-host disease in unrelated donor hematopoietic stem cell transplantation].

  Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20031101

• [Advanced liver fibrosis secondary to methotrexate treatment].

  Gastroenterologia y hepatologia 20031101

• Orbital myositis in a patient with primary biliary cirrhosis: successful treatment with methotrexate and corticosteroids.

  The Israel Medical Association journal : IMAJ 20031101

• [A case of advanced gastric cancer that responded to docetaxel with low-dose 5-FU and cisplatin combination chemotherapy after becoming chemoresistant to M-FLP].

  Gan to kagaku ryoho. Cancer & chemotherapy 20031101

• Hypoxanthine transport in human glioblastoma cells and effect on cell susceptibility to methotrexate.

  Pharmaceutical research 20031101

• Longterm observational study of methotrexate use in a Dutch cohort of 1022 patients with rheumatoid arthritis.

  The Journal of rheumatology 20031101

• The interaction of the steroidal antagonist faslodex and methotrexate.

  Cellular and molecular biology (Noisy-le-Grand, France) 20031101

• [Successful recovery of an acute myelogenous leukemia patient from a coma possibly due to leukoencephalopathy].

  [Rinsho ketsueki] The Japanese journal of clinical hematology 20031101

• [Successful radiotherapy for the thoracic cord infiltration of adult T-cell leukemia/lymphoma].

  [Rinsho ketsueki] The Japanese journal of clinical hematology 20031101

• [Management of non-surgical treatment of ectopic pregnancy].

  Journal de gynecologie, obstetrique et biologie de la reproduction 20031101

• Gold sodium thiomalate and chloroquine inhibit cytokine production in monocytic THP-1 cells through distinct transcriptional and posttranslational mechanisms.

  Journal of clinical immunology 20031101

• Lymphomatoid granulomatosis treated with rituximab and chemotherapy.

  Clinical advances in hematology & oncology : H&O 20031101

• The region between transmembrane domains 1 and 2 of the reduced folate carrier forms part of the substrate-binding pocket.

  The Journal of biological chemistry 20031017

• Treatment of corticosteroid-responsive autoimmune inner ear disease with methotrexate: a randomized controlled trial.

  JAMA 20031008

• Fluorescein-methotrexate transport in brush border membrane vesicles from rat small intestine.

  Life sciences 20031003

• Simultaneous determination of methotrexate and its eight metabolites in human whole blood by capillary zone electrophoresis.

  Journal of chromatography. A 20031003

• Inhibition of cytokine production by methotrexate. Studies in healthy volunteers and patients with rheumatoid arthritis.

  Rheumatology (Oxford, England) 20031001

• Myelotoxicity due to methotrexate - an iatrogenic cause.

  European journal of haematology 20031001

• Survival and effectiveness of leflunomide compared with methotrexate and sulfasalazine in rheumatoid arthritis: a matched observational study.

  Annals of the rheumatic diseases 20031001

• Remission of methotrexate-resistant rheumatoid arthritis after receiving 5-fluorouracil for colon cancer.

  Journal of internal medicine 20031001

• Effect of methotrexate and folinic acid on accumulation of iron in mice.

  Medical hypotheses 20031001

• HPLC determination of erythrocyte methotrexate polyglutamates after low-dose methotrexate therapy in patients with rheumatoid arthritis.

  Clinical chemistry 20031001

• Normalization of methotrexate-induced high levels of serum transaminases after ursodeoxycholic acid administration in a rheumatoid arthritis patient.

  Rheumatology (Oxford, England) 20031001

• Methotrexate-induced esophagitis in a child with Crohn disease.

  Journal of pediatric gastroenterology and nutrition 20031001

• Long-term outcomes of allogeneic stem cell transplant recipients after calcineurin inhibitor-induced neurotoxicity.

  British journal of haematology 20031001

• Allogeneic peripheral blood stem cell transplantation for high-risk non-Hodgkin's lymphoma.

  Bone marrow transplantation 20031001

• Differential effects of FK506 and methotrexate on inflammatory cytokine levels in rat adjuvant-induced arthritis.

  The Journal of rheumatology 20031001

• Medical management of a cervical pregnancy: a case report.

  Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC 20031001

• Selective estrogen receptor modulators as inhibitors of repopulation of human breast cancer cell lines after chemotherapy.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20031001

• Tacrolimus in rheumatoid arthritis patients receiving concomitant methotrexate: a six-month, open-label study.

  Arthritis and rheumatism 20031001

• Neurotoxicity of intrathecal methotrexate: MR imaging findings.

  AJNR. American journal of neuroradiology 20031001

• Inclusion body myositis in connective tissue disorders: case report and review of the literature.

  Clinical rheumatology 20031001

• A fluorine-labeled methotrexate as a probe for monitoring tumor antifolate pharmacokinetics: synthesis, in vitro cytotoxicity, and pilot in vivo 19F magnetic resonance spectra.

  Molecular cancer therapeutics 20031001

• [Cancer chemotherapy in the future. Discussion].

  Gan to kagaku ryoho. Cancer & chemotherapy 20031001

• [Adult onset Still's disease (AOSD) treated with a combination of prednisolone, cyclosporin A, and methotrexate].

  Ryumachi. [Rheumatism] 20031001

• Hyponatremia during administration of tacrolimus in an allogeneic bone marrow transplant recipient.

  International journal of hematology 20031001

• [A report of two cases--two patients of the extremely advanced hepatocellular carcinoma have responded completely for a long time after a combination therapy consisting of arterial chemotherapy and injection of interferon-alpha].

  Gan to kagaku ryoho. Cancer & chemotherapy 20031001

• Management of low-risk gestational trophoblastic neoplasia in indigent women.

  The Journal of reproductive medicine 20031001

• Management of an anaphylactoid reaction to methotrexate with a stepwise graded challenge.

  Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 20031001

• [Principles of treatment and military medical examination of the patients with indolent Non-Hodgkin's lymphomas].

  Voenno-meditsinskii zhurnal 20031001

• Effective anti-viral therapy for hemophagocytic syndrome associated with B-cell lymphoma.

  Leukemia & lymphoma 20031001

• Effect of polyglutamylation of methotrexate on its accumulation and the development of resistance in the protozoan parasite Leishmania.

  Biochemical pharmacology 20030915

• Pretreatment haemoglobin levels significantly predict the tumour response to primary chemotherapy in human breast cancer.

  British journal of cancer 20030915

• ErbB2 overexpression in human breast carcinoma is correlated with p21Cip1 up-regulation and tyrosine-15 hyperphosphorylation of p34Cdc2: poor responsiveness to chemotherapy with cyclophoshamide methotrexate, and 5-fluorouracil is associated with Erb2 overexpression and with p21Cip1 overexpression.

  Cancer 20030915

• Intensive chemotherapy with cyclophosphamide, doxorubicin, high-dose methotrexate/ifosfamide, etoposide, and high-dose cytarabine (CODOX-M/IVAC) for human immunodeficiency virus-associated Burkitt lymphoma.

  Cancer 20030915

• Lymphoblastic lymphoma of childhood and the LSA2-L2 protocol: the 30-year experience at Memorial-Sloan-Kettering Cancer Center.

  Cancer 20030915

• Inhibition of induced chemoresistance by cotreatment with (E)-5-(2-bromovinyl)-2'-deoxyuridine (RP101).

  Cancer research 20030915

• Mislocalization of membrane proteins associated with multidrug resistance in cisplatin-resistant cancer cell lines.

  Cancer research 20030915

• [Treatment of primary biliary cirrhosis].

  Orvosi hetilap 20030907

• Sirolimus, tacrolimus, and low-dose methotrexate for graft-versus-host disease prophylaxis in mismatched related donor or unrelated donor transplantation.

  Blood 20030901

• Transport of fluorescein methotrexate by multidrug resistance-associated protein 3 in IEC-6 cells.

  American journal of physiology. Gastrointestinal and liver physiology 20030901

• Outcome after hyperbaric oxygen treatment for cyclophosphamide-induced refractory hemorrhagic cystitis.

  The Journal of urology 20030901

• Medical treatment of ectopic pregnancies: a randomized clinical trial comparing methotrexate-mifepristone and methotrexate-placebo.

  Human reproduction (Oxford, England) 20030901

• Squamous cell carcinoma of the big toe successfully treated by intra-arterial infusion with methotrexate.

  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20030901

• Patients with high-risk aggressive lymphoma treated with frontline intensive chemotherapy and autografting: evidence of marked differences in outcome between patients with age-adjusted International Prognostic Index scores 2 and 3.

  Cancer 20030901

• Primary central nervous system lymphoma: Phase I evaluation of infusional bromodeoxyuridine with whole brain accelerated fractionation radiation therapy after chemotherapy.

  Cancer 20030901

• Complete remission in advanced blastic NK-cell lymphoma/leukemia in elderly patients using the hyper-CVAD regimen.

  American journal of hematology 20030901

• Endothelial dysfunction in young patients with long-term rheumatoid arthritis and low disease activity.

  Atherosclerosis 20030901

• Effect of immunostimulatory ribomunyl on the preventive treatment of rat adjuvant arthritis with cyclosporine and methotrexate.

  The Journal of rheumatology 20030901

• Therapeutic benefits of irsogladine maleate on aphthous stomatitis induced by methotrexate in rheumatoid arthritis.

  The Journal of rheumatology 20030901

• Reduced folate carrier and dihydrofolate reductase expression in acute lymphocytic leukemia may predict outcome: a Children's Cancer Group Study.

  Journal of pediatric hematology/oncology 20030901

• Successful treatment of life-threatening generalized infantile myofibromatosis using low-dose chemotherapy.

  Journal of pediatric hematology/oncology 20030901

• The influence of cyclin D1 (CCND1) 870A>G polymorphism and CCND1-thymidylate synthase (TS) gene-gene interaction on the outcome of childhood acute lymphoblastic leukaemia.

  Pharmacogenetics 20030901

• Effects of leflunomide on human cartilage.

  Farmaco (Societa chimica italiana : 1989) 20030901

• Wild-type breast cancer resistance protein (BCRP/ABCG2) is a methotrexate polyglutamate transporter.

  Cancer research 20030901

• Raynaud's phenomenon after combined adjuvant chemotherapy for breast cancer.

  Chemotherapy 20030901

• The effect of low-dose methotrexate on bone mineral density in patients with early rheumatoid arthritis.

  Rheumatology international 20030901

• Tuboovarian abscess caused by Candida glabrata in a febrile neutropenic patient.

  Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20030901

• Comparison between methotrexate and azathioprine in the treatment of chronic active Crohn's disease: a randomised, investigator-blind study.

  Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20030901

• CD34 positive selection as prophylaxis against graft versus host disease in allogeneic peripheral blood stem cell transplantation.

  Leukemia & lymphoma 20030901

• A randomized trial of induction therapy (daunorubicin, vincristine, prednisone versus daunorubicin, vincristine, prednisone, cytarabine and 6-thioguanine) in adult acute lymphoblastic leukemia with long-term follow-up: an Eastern Cooperative Oncology Group Study (E3486).

  Leukemia & lymphoma 20030901

• Post-transplant Burkitt's leukemia or lymphoma. Study of five cases treated with specific intensive therapy (PETHEMA ALL-3/97 trial).

  Leukemia & lymphoma 20030901

• Rituximab in heavily pretreated cutaneous B-cell lymphoma.

  Leukemia & lymphoma 20030901

• Genomic imbalances associated with methotrexate resistance in human osteosarcoma cell lines detected by comparative genomic hybridization-based techniques.

  European journal of cell biology 20030901

• Encouraging result of tamoxifen in a retinoblastoma patient with central nervous system metastasis.

  Pediatric hematology and oncology 20030901

• Cyclosporin A-associated status epilepticus related to hematopoietic stem cell transplantation for thalassemia.

  Pediatric hematology and oncology 20030901

• [Systemic treatment of cutaneous lupus erythematosus].

  Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20030901

• Characterization of the role of polar amino acid residues within predicted transmembrane helix 17 in determining the substrate specificity of multidrug resistance protein 3.

  Biochemistry 20030826

• Risk of acute leukemia following epirubicin-based adjuvant chemotherapy: a report from the National Cancer Institute of Canada Clinical Trials Group.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030815

• Homocysteine, pharmacogenetics, and neurotoxicity in children with leukemia.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030815

• Combined oral cyclosporin and methotrexate therapy in patients with rheumatoid arthritis elevates methotrexate levels and reduces 7-hydroxymethotrexate levels when compared with methotrexate alone.

  Rheumatology (Oxford, England) 20030801

• A functional study on polymorphism of the ATP-binding cassette transporter ABCG2: critical role of arginine-482 in methotrexate transport.

  The Biochemical journal 20030801

• Analysis of single nucleotide polymorphism C3435T of the multidrug resistance gene MDR1 in acute lymphoblastic leukemia.

  International journal of oncology 20030801

• Long term structural effects of combination therapy in patients with early rheumatoid arthritis: five year follow up of a prospective double blind controlled study.

  Annals of the rheumatic diseases 20030801

• Antifolate resistance associated with loss of MRP1 expression and function in Chinese hamster ovary cells with markedly impaired export of folate and cholate.

  Molecular pharmacology 20030801

• A molecule solves psoriasis? Systemic therapies for psoriasis inducing interleukin 4 and Th2 responses.

  Journal of molecular medicine (Berlin, Germany) 20030801

• Cisplatin, epirubicin, leucovorin and 5-fluorouracil (PELF) is more active than 5-fluorouracil, doxorubicin and methotrexate (FAMTX) in advanced gastric carcinoma.

  Annals of oncology : official journal of the European Society for Medical Oncology 20030801

• Exogenous biopterins requirement for iNOS function in vascular smooth muscle cells.

  Journal of cardiovascular pharmacology 20030801

• Cotransport of reduced glutathione with bile salts by MRP4 (ABCC4) localized to the basolateral hepatocyte membrane.

  Hepatology (Baltimore, Md.) 20030801

• Prognostic implication of cyclin E expression and its relationship with cyclin D1 and p27Kip1 expression on tissue microarrays of node negative breast cancer.

  Journal of surgical oncology 20030801

• Effects of taurine deficiency and chronic methanol administration on rat retina, optic nerve and brain amino acids and monoamines.

  Nutritional neuroscience 20030801

• Survival analyses from the ZEBRA study. goserelin (Zoladex) versus CMF in premenopausal women with node-positive breast cancer.

  European journal of cancer (Oxford, England : 1990) 20030801

• Methotrexate cytotoxicity on MCF-7 breast cancer cells is not altered by exposure to 25 Hz, 1.5 mT magnetic field and iron (III) chloride hexahydrate.

  Bioelectrochemistry (Amsterdam, Netherlands) 20030801

• Fatal interstitial pulmonary fibrosis in anti-Jo-1-negative amyopathic dermatomyositis.

  Journal of the American Academy of Dermatology 20030801

• Current systemic therapies for psoriasis: where are we now?

  Journal of the American Academy of Dermatology 20030801

• Evaluation and management of psoriatic arthritis: the role of biologic therapy.

  Journal of the American Academy of Dermatology 20030801

• A single point mutation in Drosophila dihydrofolate reductase confers methotrexate resistance to a transgenic CHO cell line.

  Genome 20030801

• Induction of graft-versus-autoimmune (GVA) disease effect against refractory psoriasis by complete donor-type chimerism and graft-versus-host disease after allogeneic hematopoietic stem cell transplantation.

  Bone marrow transplantation 20030801

• The systemic treatment of advanced and metastatic bladder cancer.

  The Lancet. Oncology 20030801

• Methotrexate therapy in asthma increases T cell susceptibility to corticosteroid inhibition.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20030801

• Methotrexate, hydroxychloroquine, and intramuscular gold in rheumatoid arthritis.

  The Journal of rheumatology 20030801

• Toward a definition and method of assessment of treatment failure and treatment effectiveness: the case of leflunomide versus methotrexate.

  The Journal of rheumatology 20030801

• Leflunomide, a new disease-modifying drug for treating active rheumatoid arthritis in methotrexate-controlled phase II clinical trial.

  Chinese medical journal 20030801

• [A case of advanced gastric cancer with liver and intra-abdominal lymph node metastasis treated by hypertensive selective chemotherapy with pharmacokinetic modulating chemotherapy].

  Gan to kagaku ryoho. Cancer & chemotherapy 20030801

• Uptake of 5-methyltetrahydrofolate into PC-3 human prostate cancer cells is carrier-mediated.

  The Journal of nutritional biochemistry 20030801

• Cytomegalovirus infection in a patient with rheumatoid arthritis.

  Joint, bone, spine : revue du rhumatisme 20030801

• Evaluation of Xenopus tropicalis as an alternative test organism for frog embryo teratogenesis assay--Xenopus (FETAX).

  Drug and chemical toxicology 20030801

• Early medical termination pregnancy with methotrexate and misoprostol in lower segment cesarean section cases.

  The journal of obstetrics and gynaecology research 20030801

• Second-line chemotherapy with bleomycin, methotrexate, and vinorelbine (BMV) for patients with squamous cell carcinoma of the head, neck and esophagus (SCC-HN&E) pretreated with a cisplatin-containing regimen: a phase II study.

  Journal of chemotherapy (Florence, Italy) 20030801

• Ovarian cancer in elderly women.

  Oncology (Williston Park, N.Y.) 20030801

• [Evaluation of surgical resection of pulmonary metastasis of trophoblastic tumour].

  Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20030801

• Upregulation of HER-2/neu by ovarian ablation: results of a randomized trial comparing leuprorelin to CMF as adjuvant therapy in node-positive breast cancer patients.

  Breast cancer research and treatment 20030801

• Adjuvant chemotherapy in early breast cancer: optimal and suboptimal anthracycline-containing regimens.

  Breast cancer research and treatment 20030801

• [Gemcitabine/cisplatin vs. MVAC. 5 year survival outcome of the phase III study of chemotherapy of advanced urothelial carcinoma in Germany].

  Der Urologe. Ausg. A 20030801

• The limited efficacy of methotrexate, actinomycin D and cisplatin (MAP) for patients with advanced testicular cancer.

  Japanese journal of clinical oncology 20030801

• [Renal tubular dysfunction in patients with rheumatoid arthritis starting with low dose of methotrexate].

  Polskie Archiwum Medycyny Wewnetrznej 20030801

• Clinical aspects of gestational trophoblastic disease: a review based partly on 25-year experience of a statewide registry.

  The Australian & New Zealand journal of obstetrics & gynaecology 20030801

• Cognitive functions in primary central nervous system lymphoma patients treated with chemotherapy and stem cell transplantation: preliminary findings.

  Clinical advances in hematology & oncology : H&O 20030801

• Design and synthesis of dihydrofolate reductase inhibitors encompassing a bridging ester group. Evaluation in a mouse colitis model.

  Journal of medicinal chemistry 20030731

• [Treatment of autoimmune hepatitis].

  Orvosi hetilap 20030727

• Validation of a flow cytometric acridine orange micronuclei methodology in rats.

  Mutation research 20030725

• Graft-versus-host disease after nonmyeloablative versus conventional hematopoietic stem cell transplantation.

  Blood 20030715

• Chemotherapy alone as initial treatment for primary CNS lymphoma in patients older than 60 years: a multicenter phase II study (26952) of the European Organization for Research and Treatment of Cancer Brain Tumor Group.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030715

• Evaluation of pain associated with oral mucositis during the acute period after administration of high-dose chemotherapy.

  Cancer 20030715

• Transport of methotrexate, methotrexate polyglutamates, and 17beta-estradiol 17-(beta-D-glucuronide) by ABCG2: effects of acquired mutations at R482 on methotrexate transport.

  Cancer research 20030715

• Study of stability of methotrexate in acidic solution spectrofluorimetric determination of methotrexate in pharmaceutical preparations through acid-catalyzed degradation reaction.

  Journal of pharmaceutical and biomedical analysis 20030714

• UK introduces measures to reduce errors with methotrexate.

  BMJ (Clinical research ed.) 20030712

• Shaping of tumor and drug-resistant genomes by instability and selection.

  Oncogene 20030710

• Colloidal anticancer drugs bioavailabilities in oral administration models.

  International journal of pharmaceutics 20030709

• Dihydrofolate reductase mutant with exceptional resistance to methotrexate but not to trimetrexate.

  Journal of medicinal chemistry 20030703

• The prevalence of patients with rheumatoid arthritis in the West Midlands fulfilling the BSR criteria for anti-tumour necrosis factor therapy: an out-patient study.

  Rheumatology (Oxford, England) 20030701

• MRI in methotrexate-related leukoencephalopathy: Disseminated necrotising leukoencephalopathy in comparison with mild leukoencephalopathy.

  Neuroradiology 20030701

• Fatal toxicity following radio- and chemotherapy of medulloblastoma in a child with unrecognized Nijmegen breakage syndrome.

  Medical and pediatric oncology 20030701

• Long-term survival in osteosarcoma patients following retinoblastoma using doxorubicin, cisplatin, and methotrexate.

  Medical and pediatric oncology 20030701

• Transient encephalopathy following high-dose methotrexate.

  Medical and pediatric oncology 20030701

• Effectiveness of a measurement feedback system on outcome in rheumatoid arthritis: a controlled clinical trial.

  Annals of the rheumatic diseases 20030701

• Identification of two differentially expressed mitochondrial genes in a methotrexate-resistant Chinese hamster cell strain derived from v79 cells using RNA fingerprinting by arbitrary primed polymerase chain reaction.

  Radiation research 20030701

• Suppressive effect of combination treatment of leflunomide and methotrexate on chemokine expression in patients with rheumatoid arthritis.

  Clinical and experimental immunology 20030701

• Prognostic value of quality of life scores for time to progression (TTP) and overall survival time (OS) in advanced breast cancer.

  European journal of cancer (Oxford, England : 1990) 20030701

• Combined chemotherapy including high-dose methotrexate in KSHV/HHV8-associated primary effusion lymphoma.

  American journal of hematology 20030701

• Erythema annulare centrifugum-type psoriasis: a particular variant of acute-eruptive psoriasis.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20030701

• Psoriasis, vasculitis and methotrexate.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20030701

• Dose reduction of coadministered 6-mercaptopurine decreases myelotoxicity following high-dose methotrexate in childhood leukemia.

  Leukemia 20030701

• Methotrexate vs Cyclosporin A as a single agent for graft-versus-host disease prophylaxis in pediatric patients with hematological malignancies undergoing allogeneic bone marrow transplantation from HLA-identical siblings: a single-center analysis in Japan.

  Bone marrow transplantation 20030701

• Five-year followup of rheumatoid arthritis patients after early treatment with disease-modifying antirheumatic drugs versus treatment according to the pyramid approach in the first year.

  Arthritis and rheumatism 20030701

• Bioavailability of oral vs. subcutaneous low-dose methotrexate in patients with Crohn's disease.

  Alimentary pharmacology & therapeutics 20030701

• Neoadjuvant chemotherapy for osteosarcoma of the extremities with metastases at presentation: recent experience at the Rizzoli Institute in 57 patients treated with cisplatin, doxorubicin, and a high dose of methotrexate and ifosfamide.

  Annals of oncology : official journal of the European Society for Medical Oncology 20030701

• Rare expression of epithelial cell adhesion molecule on residual micrometastatic breast cancer cells after adjuvant chemotherapy.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20030701

• Dactylitis of the thumb extending to the radial bursa.

  The Journal of rheumatology 20030701

• Down-regulation of thiamine transporter THTR2 gene expression in breast cancer and its association with resistance to apoptosis.

  Molecular cancer research : MCR 20030701

• Minimally invasive management of 14.5-week abdominal pregnancy without laparotomy: a novel approach using percutaneous sonographically guided feticide and systemic methotrexate.

  Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine 20030701

• Generation of dendritic cells from the ventricular fluid in patients with meningeal carcinomatosis.

  Journal of neuroimmunology 20030701

• [Indication and effect of immunosuppression in patients with scleritis].

  Klinische Monatsblatter fur Augenheilkunde 20030701

• Acrylic cement added with antiblastics in the treatment of bone metastases. Ultrastructural and in vitro analysis.

  The Journal of bone and joint surgery. British volume 20030701

• Viable cervical pregnancy managed with systemic Methotrexate, uterine artery embolization, and local tamponade with inflated Foley catheter balloon.

  American journal of perinatology 20030701

• Quadriparesis in a young female suffering from rheumatoid arthritis.

  The Journal of the Association of Physicians of India 20030701

• [Results and suggestion from comparing between world excellent protocols of childhood acute lymphoblastic leukemia].

  Zhonghua er ke za zhi = Chinese journal of pediatrics 20030701

• Development of apoptosis-resistant dihydrofolate reductase-deficient Chinese hamster ovary cell line.

  Biotechnology and bioengineering 20030630

• Evidence for two interacting ligand binding sites in human multidrug resistance protein 2 (ATP binding cassette C2).

  The Journal of biological chemistry 20030627

• Residues 45 and 404 in the murine reduced folate carrier may interact to alter carrier binding and mobility.

  Biochimica et biophysica acta 20030627

• A bifunctional molecule that displays context-dependent cellular activity.

  Journal of the American Chemical Society 20030625

• ABCG2 transports sulfated conjugates of steroids and xenobiotics.

  The Journal of biological chemistry 20030620

• Quality-of-life-adjusted survival comparison of sustained-release cytosine arabinoside versus intrathecal methotrexate for treatment of solid tumor neoplastic meningitis.

  Cancer 20030615

• Presentation serum selenium predicts for overall survival, dose delivery, and first treatment response in aggressive non-Hodgkin's lymphoma.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030615

• Can endocrine treatment for hormone-positive premenopausal women with early breast cancer replace adjuvant chemotherapy?

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030615

• Paradigm shift in adjuvant treatment of receptor positive premenopausal breast cancer patients? Not yet!

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030615

• Combined endocrine blockade in premenopausal breast cancer: a superior therapeutic option for adjuvant management?

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030615

• Epidermal growth factor receptor (EGFR)-targeted immunoliposomes mediate specific and efficient drug delivery to EGFR- and EGFRvIII-overexpressing tumor cells.

  Cancer research 20030615

• Non-steroidal anti-inflammatory drugs affect the methotrexate transport in IEC-6 cells.

  Life sciences 20030613

• Influence of high-dose methotrexate therapy (HD-MTX) on glomerular and tubular kidney function.

  Medical and pediatric oncology 20030601

• Imatinib Mesylate (Gleevec) is a useful agent in the salvage treatment of adults with relapsed/refractory Philadelphia positive acute leukemias.

  Hematology (Amsterdam, Netherlands) 20030601

• Decreased transfusion requirements in patients given stem cell allografts using a non-myeloablative conditioning regimen: a single institution experience.

  Hematology (Amsterdam, Netherlands) 20030601

• A phase III trial of sequential adjuvant chemotherapy for operable breast carcinoma: final analysis with 10-year follow-up.

  Cancer 20030601

• High-dose sequential chemotherapy and peripheral blood progenitor cell autografting in patients with refractory and/or recurrent Hodgkin lymphoma: a multicenter study of the intergruppo Italiano Linfomi showing prolonged disease free survival in patients treated at first recurrence.

  Cancer 20030601

• Simultaneous occurrence of hepatic focal nodular hyperplasia and uterine endometrial stromal nodule in a patient having treated breast infiltrating ductal carcinoma.

  Acta obstetricia et gynecologica Scandinavica 20030601

• Surgical management of cataracts in children with juvenile rheumatoid arthritis-associated uveitis.

  American journal of ophthalmology 20030601

• Doxorubicin in combination with fluorouracil and cyclophosphamide (i.v. FAC regimen, day 1, 21) versus methotrexate in combination with fluorouracil and cyclophosphamide (i.v. CMF regimen, day 1, 21) as adjuvant chemotherapy for operable breast cancer: a study by the GEICAM group.

  Annals of oncology : official journal of the European Society for Medical Oncology 20030601

• Successful treatment of bcr/abl-positive acute mixed lineage leukemia by unmanipulated bone marrow transplantation from an HLA-haploidentical (3-antigen-mismatched) cousin.

  Bone marrow transplantation 20030601

• Pregnancy after EMA/CO for gestational trophoblastic disease: a report from The Netherlands.

  BJOG : an international journal of obstetrics and gynaecology 20030601

• A simple method for enriching populations of transfected CHO cells for cells of higher specific productivity.

  Journal of immunological methods 20030601

• Intrathecal chemotherapy for recurrent central nervous system intraocular lymphoma.

  Ophthalmology 20030601

• Antagonism by methotrexate on mercaptopurine disposition in lymphoblasts during up-front treatment of acute lymphoblastic leukemia.

  Clinical pharmacology and therapeutics 20030601

• Intracarotid administration of short-chain alkylglycerols for increased delivery of methotrexate to the rat brain.

  British journal of pharmacology 20030601

• mRNA expression levels of E2F transcription factors correlate with dihydrofolate reductase, reduced folate carrier, and thymidylate synthase mRNA expression in osteosarcoma.

  Molecular cancer therapeutics 20030601

• Long-term survival in acute lymphoblastic leukaemia in adults treated according to the LALA 87 protocol.

  Chemotherapy 20030601

• Activity of a novel anti-folate (PDX, 10-propargyl 10-deazaaminopterin) against human lymphoma is superior to methotrexate and correlates with tumor RFC-1 gene expression.

  Leukemia & lymphoma 20030601

• Addition of a low fixed number of CD3+ cells to CD34-enriched allografts: effects on engraftment, graft-versus-host disease, and survival after related and unrelated peripheral stem cell transplantation.

  Journal of hematotherapy & stem cell research 20030601

• Methotrexate pneumonitis in a patient with rheumatoid arthritis.

  Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 20030601

• Current disease-modifying therapies in multiple sclerosis.

  Seminars in neurology 20030601

• Unstratified chemotherapy for non-metastatic osteosarcoma of the extremities in children.

  Journal of the Formosan Medical Association = Taiwan yi zhi 20030601

• Landmark adjuvant randomized clinical trials of systemic therapy in early breast cancer.

  Drugs of today (Barcelona, Spain : 1998) 20030601

• Cyclophosphamide, methotrexate, and cytarabine embropathy: is apoptosis the common pathway?

  Birth defects research. Part A, Clinical and molecular teratology 20030601

• Non-hodgkins lymphoma.

  Clinical evidence 20030601

• Reversal of marrow fibrosis in agnogenic myeloid metaplasia by allogeneic peripheral blood stem cell transplantation.

  Asian Pacific journal of allergy and immunology 20030601

• [Treatment of patients with juvenile rheumatoid arthritis with combination of leflunomide and methotrexate].

  Zhonghua er ke za zhi = Chinese journal of pediatrics 20030601

• Rheumatoid arthritis.

  Clinical evidence 20030601

• [Combination therapy in rheumatoid arthritis].

  Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20030529

• Dexamethasone versus prednisone and daily oral versus weekly intravenous mercaptopurine for patients with standard-risk acute lymphoblastic leukemia: a report from the Children's Cancer Group.

  Blood 20030515

• Primary metastatic osteosarcoma: presentation and outcome of patients treated on neoadjuvant Cooperative Osteosarcoma Study Group protocols.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030515

• Prolonged perilesional edema after treatment of parenchymal neurocysticercosis: methotrexate as a corticosteroid-sparing agent.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20030515

• Multidrug resistance protein (MRP) 1 and MRP3 attenuate cytotoxic and transactivating effects of the cyclopentenone prostaglandin, 15-deoxy-Delta(12,14)prostaglandin J2 in MCF7 breast cancer cells.

  Biochemistry 20030513

• Treatment of refractory juvenile idiopathic arthritis via pulse therapy using methylprednisolone and cyclophosphamide.

  Sao Paulo medical journal = Revista paulista de medicina 20030505

• Inactivation of deoxycytidine kinase and overexpression of P-glycoprotein in AraC and daunorubicin double resistant leukemic cell lines.

  Leukemia research 20030501

• Pharmacophore-based molecular docking to account for ligand flexibility.

  Proteins 20030501

• Automated generation of MCSS-derived pharmacophoric DOCK site points for searching multiconformation databases.

  Proteins 20030501

• Melatonin prevents methotrexate-induced hepatorenal oxidative injury in rats.

  Journal of pineal research 20030501

• Polymorphisms in the thymidylate synthase and methylenetetrahydrofolate reductase genes and sensitivity to the low-dose methotrexate therapy in patients with rheumatoid arthritis.

  International journal of molecular medicine 20030501

• Factors associated with toxicity, final dose, and efficacy of methotrexate in patients with rheumatoid arthritis.

  Annals of the rheumatic diseases 20030501

• Methotrexate is the leading DMARD in Finland.

  Annals of the rheumatic diseases 20030501

• New insights into the immunopathogenesis and treatment of small vessel vasculitis of the kidney.

  Current opinion in nephrology and hypertension 20030501

• Second malignancies following adjuvant chemotherapy: 6-year results from a Belgian randomized study comparing cyclophosphamide, methotrexate and 5-fluorouracil (CMF) with an anthracycline-based regimen in adjuvant treatment of node-positive breast cancer patients.

  Annals of oncology : official journal of the European Society for Medical Oncology 20030501

• Vinorelbine, methotrexate and fluorouracil (VMF) as first-line therapy in metastatic breast cancer: a randomized phase II trial.

  Annals of oncology : official journal of the European Society for Medical Oncology 20030501

• Treatment-specific changes in gene expression discriminate in vivo drug response in human leukemia cells.

  Nature genetics 20030501

• Enantioseparation using cyclosophoraoses as a novel chiral additive in capillary electrophoresis.

  Carbohydrate research 20030501

• Large-dose intravenous methotrexate-induced cutaneous toxicity: can oral magnesium oxide reduce pain?

  Anesthesia and analgesia 20030501

• Albumin-based drug delivery as novel therapeutic approach for rheumatoid arthritis.

  Journal of immunology (Baltimore, Md. : 1950) 20030501

• Different responses to preoperative chemotherapy for invasive lobular and invasive ductal breast carcinoma.

  European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 20030501

• Biochemical and clinical aspects of methotrexate neurotoxicity.

  Chemotherapy 20030501

• Primary mediastinal large B-cell lymphoma with sclerosis in pediatric and adolescent patients: treatment and results from three therapeutic studies of the Berlin-Frankfurt-Münster Group.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030501

• Natural history of more than 20 years of node-positive primary breast carcinoma treated with cyclophosphamide, methotrexate, and fluorouracil-based adjuvant chemotherapy: a study by the Cancer and Leukemia Group B.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030501

• Side effects of adjuvant endocrine treatment in premenopausal breast cancer patients: a prospective randomized study.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030501

• Acute hypokalemic tetraparesis induced by intravenous methotrexate.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030501

• Acute toxicity of concurrent adjuvant radiotherapy and chemotherapy (CMF or AC) in breast cancer patients. a prospective, comparative, non-randomised study.

  European journal of cancer (Oxford, England : 1990) 20030501

• Gestational trophoblastic tumor after medical abortion.

  Obstetrics and gynecology 20030501

• In vitro and in vivo antitumor activity of methotrexate conjugated to human serum albumin in human cancer cells.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20030501

• Cogan's syndrome presenting as Sjögren's syndrome followed by acute aortic regurgitation.

  Clinical rheumatology 20030501

• Postmolar surveillance at a trophoblastic disease center that serves indigent women.

  American journal of obstetrics and gynecology 20030501

• Prognostic value of cyclic GMP in patients undergoing allogeneic bone marrow transplantation after conditioning with total body irradiation.

  Bone marrow transplantation 20030501

• [Methotrexate in conjunction with meloxicam for treating ankylosing spondylitis: a clinical observation of the efficacy and safety].

  Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20030501

• Phase 1/2 pilot study of methotrexate-laurocapram topical gel for the treatment of patients with early-stage mycosis fungoides.

  Archives of dermatology 20030501

• A lupus-like syndrome associated with infliximab therapy.

  Inflammatory bowel diseases 20030501

• [Male breast cancer].

  Gan to kagaku ryoho. Cancer & chemotherapy 20030501

• [Combined MTX.5-FU.CDGP for the treatment of head and neck cancer].

  Gan to kagaku ryoho. Cancer & chemotherapy 20030501

• Brachytherapy boost to the tumour bed in high risk patients after limited surgery for breast cancer.

  Clinical oncology (Royal College of Radiologists (Great Britain)) 20030501

• [Retroperitoneal fibrosarcoma. Apropos of a case].

  Archivos espanoles de urologia 20030501

• [Rare opportunistic disease in a patient treated with immunosuppressive therapy for rheumatoid arthritis].

  Anales de medicina interna (Madrid, Spain : 1984) 20030501

• [Sub-cutaneous location of Burkitt's lymphoma. Apropos of 1 case at Yopougon Central University Hospital, Abidjan (Côte d'Ivoire)].

  Bulletin de la Societe de pathologie exotique (1990) 20030501

• [Auto-immune hepatitis: therapeutic management].

  Gastroenterologie clinique et biologique 20030501

• A case of primary plasma cell leukemia with hairy-cell morphology and lambda-type Bence-Jones protein. Immunohistochemical and molecular analysis.

  Japanese journal of clinical oncology 20030501

• Kinetic modeling of triamterene intestinal absorption and its inhibition by folic acid and methotrexate.

  Journal of drug targeting 20030501

• [Tormenting muscle pains refractory to all treatment attempts. Finally cortisone therapy leads to right track].

  MMW Fortschritte der Medizin 20030424

• [Human leukocyte antigen mismatched hemopietic stem cell transplants for the treatment of leukemia].

  Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20030418

• [Cerebral metastasis in choriocarcinoma a case report].

  Praxis 20030416

• Presurgical chemotherapy compared with immediate surgery and adjuvant chemotherapy for nonmetastatic osteosarcoma: Pediatric Oncology Group Study POG-8651.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030415

• Use of a cyclophosphamide-induction methotrexate-maintenance regimen for the treatment of Wegener's granulomatosis: extended follow-up and rate of relapse.

  The American journal of medicine 20030415

• Cyclosporin A monotherapy versus cyclosporin A and methotrexate combination therapy in patients with early rheumatoid arthritis: a double blind randomised placebo controlled trial.

  Annals of the rheumatic diseases 20030401

• Concurrent sequencing of full-dose CMF chemotherapy and radiation therapy in early breast cancer has no effect on treatment delivery.

  European journal of cancer (Oxford, England : 1990) 20030401

• Molecular cloning and expression of the dihydrofolate reductase (DHFR) gene from adult buffalo fly (Haematobia irritans exigua): effects of antifolates.

  Insect molecular biology 20030401

• Ten-year outcome after combined modality therapy for inflammatory breast cancer.

  International journal of radiation oncology, biology, physics 20030401

• Salvage treatment with etoposide (VP-16), ifosfamide and cytarabine (Ara-C) for patients with recurrent primary central nervous system lymphoma.

  European journal of haematology 20030401

• Early autologous stem-cell transplantation versus conventional chemotherapy as front-line therapy in high-risk, aggressive non-Hodgkin's lymphoma: an Italian multicenter randomized trial.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030401

• Intensification of mercaptopurine/methotrexate maintenance chemotherapy may increase the risk of relapse for some children with acute lymphoblastic leukemia.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030401

• Pharmacoeconomics of medical abortion: a review of cost in the United States, Europe and Asia.

  Expert opinion on pharmacotherapy 20030401

• Cutaneous ulceration with methotrexate.

  Prescrire international 20030401

• Fertility in male patients treated with neoadjuvant chemotherapy for osteosarcoma.

  Journal of pediatric hematology/oncology 20030401

• Induction of long-term remission of a relapsed childhood B-acute lymphoblastic leukemia with rituximab chimeric anti-CD20 monoclonal antibody and autologous stem cell transplantation.

  Journal of pediatric hematology/oncology 20030401

• Alternate treatments in asthma.

  Chest 20030401

• Disparate results in studies of methotrexate plus corticosteroids in the treatment of giant cell arteritis: comment on the article by Hoffman et al.

  Arthritis and rheumatism 20030401

• Vision loss in giant cell arteritis patients treated with alternate-day corticosteroids: comment on the article by Hoffman et al.

  Arthritis and rheumatism 20030401

• Low-dose continuous chemotherapy for metastatic melanoma: a phase II trial.

  Melanoma research 20030401

• Cognitive performance and magnetic resonance imaging findings after high-dose systemic and intraventricular chemotherapy for primary central nervous system lymphoma.

  Archives of neurology 20030401

• Intrathecal methotrexate-induced acute cerebellar syndrome.

  Annals of hematology 20030401

• Termination of disease-modifying antirheumatic drugs in rheumatoid arthritis and in psoriatic arthritis. A comparative study of 270 cases.

  Zeitschrift fur Rheumatologie 20030401

• High-dose methotrexate: on the relationship of methotrexate elimination time vs renal function and serum methotrexate levels in 1164 courses in 264 Swedish children with acute lymphoblastic leukaemia (ALL).

  Cancer chemotherapy and pharmacology 20030401

• 21. The adjuvant treatment of breast cancer.

  International journal of clinical practice 20030401

• Epithelioid trophoblastic tumour: report of a case in the fallopian tube.

  Pathology 20030401

• Acute promyelocytic leukemia: a case-based review.

  Hematology (Amsterdam, Netherlands) 20030401

• Psoriatic arthritis: a guide for dermatology nurses.

  Dermatology nursing 20030401

• Current status and future of relapsed primary central nervous system lymphoma (PCNSL).

  Leukemia & lymphoma 20030401

• Adjuvant chemotherapy in breast cancer: back to the future.

  Onkologie 20030401

• Randomised trial: One cycle of anthracycline-containing adjuvant chemotherapy compared with six cycles of CMF treatment in node-positive, hormone receptor-negative breast cancer patients.

  Onkologie 20030401

• [Cerebral ischemic events and anti-cancer therapy].

  Revue neurologique 20030401

• Allergic contact dermatitis in methotrexate manufacture.

  Contact dermatitis 20030401

• The induction of apoptosis by methotrexate in activated lymphocytes as indicated by fluorescence hyperpolarization: a possible model for predicting methotrexate therapy for rheumatoid arthritis patients.

  Cell structure and function 20030401

• [Study on the genetic alterations in MTX-resistant cells by differential polymerase chain reaction].

  Yi chuan xue bao = Acta genetica Sinica 20030401

• [Can a combination therapy with leflunomide be recommended for patients with active rheumatoid arthritis?].

  Zeitschrift fur Rheumatologie 20030401

• [Acute respiratory distress syndrome due to pneumonitis following intrathecal methotrexate administration].

  Revue des maladies respiratoires 20030401

• [Erb-2 overexpression in breast cancer].

  Ginekologia polska 20030401

• Conservative management of placenta accreta and unruptured interstitial cornual pregnancy using methotrexate.

  European journal of obstetrics, gynecology, and reproductive biology 20030326

• Retroviral transduction of a mutant dihydrofolate reductase-thymidylate synthase fusion gene into murine marrow cells confers resistance to both methotrexate and 5-fluorouracil.

  Human gene therapy 20030320

• Related umbilical cord blood transplantation in patients with thalassemia and sickle cell disease.

  Blood 20030315

• Optimal chemotherapy for women with breast cancer: the plot thickens.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030315

• Regulatory approvals of pediatric oncology drugs: previous experience and new initiatives.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030315

• Methotrexate stimulates lung epithelial cells to release inflammatory cell chemotactic activities.

  Experimental lung research 20030301

• Long-term sequelae in children treated for brain tumors: impairments, disability, and handicap.

  Pediatric hematology and oncology 20030301

• High survival rate in childhood non-Hodgkin lymphoma without CNS involvement: results of BFM 95 study in Kuwait.

  Pediatric hematology and oncology 20030301

• Benign intracranial hypertension in association with acute lymphoblastic leukemia.

  Pediatric hematology and oncology 20030301

• Mucosal permeability regulates receptor binding of luminal epidermal growth factor in the adult rat intestine.

  International journal of molecular medicine 20030301

• Use of methotrexate in juvenile idiopathic arthritis.

  Archives of disease in childhood 20030301

• Use of plasma exchange in methotrexate removal in a patient with osteosarcoma and acute renal insufficiency.

  American journal of hematology 20030301

• Reduced-intensity bone marrow transplantation from an alternative unrelated donor for myelodysplastic syndrome of first-donor origin.

  American journal of hematology 20030301

• Expression of cell cycle regulatory proteins in breast carcinomas before and after preoperative chemotherapy.

  Breast cancer research and treatment 20030301

• The utility of positron emission tomography in the evaluation of autoimmune hearing loss.

  Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 20030301

• Use of methotrexate in sarcoid-associated optic neuropathy.

  Ophthalmology 20030301

• Cyclosporin A and methotrexate are equally effective in reducing T cell numbers in psoriatic skin lesions but have no consistent effect on IFN-gamma and IL-4 expression in psoriatic skin in situ.

  Archives of dermatological research 20030301

• Continuing chemotherapy or not after the induction treatment in advanced breast cancer patients. clinical outcomes and oncologists' preferences.

  European journal of cancer (Oxford, England : 1990) 20030301

• Serum transthyretin monomer as a possible marker of blood-to-CSF barrier disruption.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20030301

• Sulfate conjugating and transport functions of MDCK distal tubular cells.

  Kidney international 20030301

• An index of the three core data set patient questionnaire measures distinguishes efficacy of active treatment from that of placebo as effectively as the American College of Rheumatology 20% response criteria (ACR20) or the Disease Activity Score (DAS) in a rheumatoid arthritis clinical trial.

  Arthritis and rheumatism 20030301

• Mifepristone and misoprostol and methotrexate/misoprostol in clinical practice for abortion.

  American journal of obstetrics and gynecology 20030301

• Successful reintroduction of methotrexate after acute pneumonitis in a patient with acute lymphoblastic leukemia.

  Annals of hematology 20030301

• Proteome mapping of the protozoan parasite Leishmania and application to the study of drug targets and resistance mechanisms.

  Molecular & cellular proteomics : MCP 20030301

• Early diagnosis and stage-adapted treatment of Wegener's granulomatosis.

  The Journal of laryngology and otology 20030301

• Low dose methotrexate in inflammatory bowel disease: current status and future directions.

  The American journal of gastroenterology 20030301

• Effects of sodium in hydration solution on plasma methotrexate concentrations following high-dose methotrexate in children with acute lymphoblastic leukemia.

  Cancer chemotherapy and pharmacology 20030301

• Steroid myopathy in a child with juvenile rheumatoid arthritis. Case report.

  Panminerva medica 20030301

• The dose related effect of steroids on blast reduction rate and event free survival in children with acute lymphoblastic leukemia.

  Leukemia & lymphoma 20030301

• [Treatment of Crohn's disease].

  Therapeutische Umschau. Revue therapeutique 20030301

• [Study on graft-versus-host disease in the allogeneic peripheral blood stem cell transplantation for the treatment of leukemia].

  Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20030301

• Position statement: immunomodulator therapy for inflammatory Bowel disease.

  The Israel Medical Association journal : IMAJ 20030301

• Loss of multidrug resistance protein 1 expression and folate efflux activity results in a highly concentrative folate transport in human leukemia cells.

  The Journal of biological chemistry 20030227

• [Expression of human-mouse chimeric antibody ch-BD1 and its affinity to human bladder cancer in vitro and in vivo].

  Zhonghua yi xue za zhi 20030225

• The coordination of the isomerization of a conserved non-prolyl cis peptide bond with the rate-limiting steps in the folding of dihydrofolate reductase.

  Journal of molecular biology 20030214

• Design, synthesis, and biological activities of classical N-[4-[2-(2-amino-4-ethylpyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-l-glutamic acid and its 6-methyl derivative as potential dual inhibitors of thymidylate synthase and dihydrofolate reductase and as potential antitumor agents.

  Journal of medicinal chemistry 20030213

• Designing protein dimerizers: the importance of ligand conformational equilibria.

  Journal of the American Chemical Society 20030212

• Substitution of Trp1242 of TM17 alters substrate specificity of human multidrug resistance protein 3.

  American journal of physiology. Gastrointestinal and liver physiology 20030201

• Post-induction residual disease in translocation t(12;21)-positive childhood ALL.

  Medical and pediatric oncology 20030201

• Perfusion MRI and SPECT of brain after treatment for childhood acute lymphoblastic leukemia.

  Medical and pediatric oncology 20030201

• Inflammatory bowel disease in pregnancy.

  Gut 20030201

• Potent inhibition of human folylpolyglutamate synthetase by a phosphinic acid mimic of the tetrahedral reaction intermediate.

  Biochemical pharmacology 20030201

• Characterization of the transport properties of human multidrug resistance protein 7 (MRP7, ABCC10).

  Molecular pharmacology 20030201

• Combined-modality treatment of leptomeningeal gliomatosis.

  Neurosurgery 20030201

• Transport of 5-formyltetrahydrofolate into primary cultured rat astrocytes.

  Archives of biochemistry and biophysics 20030201

• HER2 overexpression and doxorubicin in adjuvant chemotherapy for resectable breast cancer.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030201

• Value of P-glycoprotein and clinicopathologic factors as the basis for new treatment strategies in high-grade osteosarcoma of the extremities.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030201

• Accelerated versus standard cyclophosphamide, epirubicin and 5-fluorouracil or cyclophosphamide, methotrexate and 5-fluorouracil: a randomized phase III trial in locally advanced breast cancer.

  Annals of oncology : official journal of the European Society for Medical Oncology 20030201

• The use of disease modifying antirheumatic drugs in women with rheumatoid arthritis of childbearing age: a survey of practice patterns and pregnancy outcomes.

  The Journal of rheumatology 20030201

• High-dose 5-fluorouracil plus low dose methotrexate plus or minus low-dose PALA in advanced colorectal cancer: a randomised phase II-III trial of the EORTC Gastrointestinal Group.

  European journal of cancer (Oxford, England : 1990) 20030201

• The anti-inflammatory actions of methotrexate are critically dependent upon the production of reactive oxygen species.

  British journal of pharmacology 20030201

• Effect of caffeine consumption on efficacy of methotrexate in rheumatoid arthritis.

  Arthritis and rheumatism 20030201

• RNA expression of breast cancer resistance protein, lung resistance-related protein, multidrug resistance-associated proteins 1 and 2, and multidrug resistance gene 1 in breast cancer: correlation with chemotherapeutic response.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20030201

• [Value of serum progesterone for ectopic pregnancy in therapeutic effect monitoring].

  Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20030201

• Risk of abnormal pregnancy completing chemotherapy for gestational trophoblastic tumor.

  Gynecologic oncology 20030201

• The combination of calcipotriol and methotrexate compared with methotrexate and vehicle in psoriasis: results of a multicentre placebo-controlled randomized trial.

  The British journal of dermatology 20030201

• Advanced ureteral cancer with complete remission achieved by taxan containing systemic chemotherapy.

  International journal of urology : official journal of the Japanese Urological Association 20030201

• Predictors of success in methotrexate treatment of women with unruptured tubal pregnancies.

  Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 20030201

• [The rheumatologist's conflict between 'off-label' prescription and failure to render assistance].

  Zeitschrift fur Rheumatologie 20030201

• Deoxycoformycin-containing combination chemotherapy for adult T-cell leukemia-lymphoma: Japan Clinical Oncology Group Study (JCOG9109).

  International journal of hematology 20030201

• Methotrexate-induced acral erythema with bullous reaction.

  Dermatology online journal 20030201

• A new approach to the diagnosis and treatment of intravascular lymphoma.

  Journal of neuro-oncology 20030201

• Large diversity in transport-mediated methotrexate resistance in human leukemia cell line CCRF-CEM established in a high concentration of leucovorin.

  Cancer science 20030201

• [Psoriasis and systemic lupus erythematosus: a rare association with specific therapeutic problems].

  Annales de medecine interne 20030201

• Posterior leukoencephalopathy following intrathecal chemotherapy with MRA-documented vasospasm.

  Neurology 20030128

• [Evidence-based treatment of methotrexate-resistant rheumatoid arthritis. Combinations of conventional disease-modifying antirheumatic agents].

  Deutsche medizinische Wochenschrift (1946) 20030124

• Effect of methylenetetrahydrofolate reductase 677C-->T polymorphism on toxicity and homocysteine plasma level after chronic methotrexate treatment of ovarian cancer patients.

  International journal of cancer 20030120

• Non-classical antifolates, 5-(N-phenylpyrrolidin-3-yl)-2,4,6-triaminopyrimidines and 2,4-Diamino-6(5H)-oxopyrimidines, synthesis and antitumor studies.

  Bioorganic & medicinal chemistry 20030102

• Subacute leukencephalopathy after low-dose intrathecal methotrexate in an adolescent heterozygous for the MTHFR C677T polymorphism.

  Medical and pediatric oncology 20030101

• Effect of oral contraceptive on ovarian function in young females undergoing neoadjuvant chemotherapy treatment for osteosarcoma.

  Oncology reports 20030101

• Dental abnormalities in children after chemotherapy treatment for acute lymphoid leukemia.

  Leukemia research 20030101

• Will pharmacogenetics allow better prediction of methotrexate toxicity and efficacy in patients with rheumatoid arthritis?

  Annals of the rheumatic diseases 20030101

• High-dose methotrexate clearance following prior vancomycin administration: no significant interaction in the absence of overt renal impairment.

  Annals of oncology : official journal of the European Society for Medical Oncology 20030101

• Adjuvant chemotherapy with cyclophosphamide, methotrexate, and 5-fluorouracil, vincristine, and prednisone compared with single-agent L-phenylalanine mustard for patients with operable breast carcinoma and positive axillary lymph nodes: 20-year results of a Southwest Oncology Group study.

  Cancer 20030101

• Pancytopenia associated with leflunomide and methotrexate.

  The Annals of pharmacotherapy 20030101

• HHV8-related non-Hodgkin's lymphoma of the spermatic cord in a patient with HIV-associated multicentric Castleman disease.

  American journal of hematology 20030101

• Bone status evaluation with calcaneal ultrasound in children with chronic rheumatic diseases. A one year followup study.

  The Journal of rheumatology 20030101

• Life-threatening reversible bone marrow toxicity in a rheumatoid arthritis patient switched from leflunomide to infliximab.

  Rheumatology (Oxford, England) 20030101

• Recent progress in ankylosing spondylitis treatment.

  Expert opinion on pharmacotherapy 20030101

• Methotrexate therapy for primary biliary cirrhosis.

  The American journal of gastroenterology 20030101

• Efficacy of colchicine in patients with primary biliary cirrhosis poorly responsive to ursodiol and methotrexate.

  The American journal of gastroenterology 20030101

• Adenosine A2A or A3 receptors are required for inhibition of inflammation by methotrexate and its analog MX-68.

  Arthritis and rheumatism 20030101

• Unproven hypothesis that leflunomide is better than methotrexate as measured by magnetic resonance imaging: comment on the article by Reece et al.

  Arthritis and rheumatism 20030101

• Leflunomide for treating rheumatoid arthritis.

  The Cochrane database of systematic reviews 20030101

• Pharmacokinetics and pharmacodynamics of methotrexate in non-neoplastic diseases.

  Clinical pharmacokinetics 20030101

• Baboons undergoing orthotopic concordant cardiac xenotransplantation surviving more than 300 days: effect of immunosuppressive regimen.

  The Journal of thoracic and cardiovascular surgery 20030101

• [Chronically active Crohn's disease].

  Zeitschrift fur Gastroenterologie 20030101

• [Maintaining a remission].

  Zeitschrift fur Gastroenterologie 20030101

• The effects of chemotherapeutic agents on the regulation of thrombin on cell surfaces.

  British journal of haematology 20030101

• Combination therapy in childhood leukaemia: in vitro studies of thiopurines and inhibitors of purine metabolism on apoptosis.

  Annals of clinical biochemistry 20030101

• Successful desensitization to high-dose methotrexate after systemic anaphylaxis.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20030101

• Prevalence of dermatophytosis in patients with rheumatoid arthritis.

  Rheumatology international 20030101

• [Inflammatory bowel diseases (IBD) -- critical discussion of etiology, pathogenesis, diagnostics, and therapy].

  Der Radiologe 20030101

• The immunoassay of methotrexate by capillary electrophoresis with laser-induced fluorescence detection.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20030101

• Assessment of the intestinal permeability following postoperative chemotherapy for human malignant disease.

  European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes 20030101

• Ocular cicatricial pemphigoid.

  Clinical & experimental optometry 20030101

• Difficult treatment issues in sarcoidosis.

  Journal of internal medicine 20030101

• Effects of non-steroidal anti-inflammatory drugs on the methotrexate transport in rat small intestine.

  Scandinavian journal of gastroenterology 20030101

• Impact of Mrp2 on the biliary excretion and intestinal absorption of furosemide, probenecid, and methotrexate using Eisai hyperbilirubinemic rats.

  Pharmaceutical research 20030101

• [Bladder cancer: realities and perspectives].

  Bulletin du cancer 20030101

• Primary NK/T cell lymphoma of the testis. A case report and review of the literature.

  Acta haematologica 20030101

• Gestational trophoblastic syndrome: an audit of 112 patients. A South African experience.

  International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20030101

• Successful use of anti-retroviral therapy in combination with cytotoxic chemotherapy for persistent molar pregnancy: a case report.

  International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20030101

• Sclerosing encapsulating peritonitis (SEP) as a delayed complication of continuous hyperthermic peritoneal perfusion (CHPP): report of a case.

  Surgery today 20030101

• Nasal NK/T-cell lymphoma with disseminated disease treated with aggressive combined therapy.

  Medical oncology (Northwood, London, England) 20030101

• Orbital myositis in a rheumatoid arthritis patient during etanercept treatment.

  Clinical and experimental rheumatology 20030101

• [Griscelli syndrome: a case report].

  Klinische Padiatrie 20030101

• High-dose daunorubicin as liposomal compound (Daunoxome) in elderly patients with acute lymphoblastic leukemia.

  The hematology journal : the official journal of the European Haematology Association 20030101

• Identification of chemotherapeutic refractory cases based on human chorionic gonadotropin values among patients with low-risk persistent trophoblastic disease treated with 8-day methotrexate-folinic acid.

  European journal of gynaecological oncology 20030101

• [Drug safety. Preventing medication errors].

  Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20030101

• Responsiveness of skin metastases to CMF in a patient with urothelial carcinoma of the bladder: a case report.

  Tumori 20030101

• Primary colorectal T-cell lymphoma.

  Journal of gastroenterology 20030101

• Hyperhomocysteinemia in children with juvenile idiopathic arthritis is not influenced by methotrexate treatment and folic acid supplementation: a pilot study.

  Clinical and experimental rheumatology 20030101

• Biphenotypic acute leukemia following intensive adjuvant chemotherapy for breast cancer: case report and review of the literature.

  The breast journal 20030101

• S-1 in the treatment of advanced and recurrent gastric cancer: current state and future prospects.

  Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 20030101

• Paraneoplastic pemphigus with bronchiolitis obliterans in a child.

  Pediatric dermatology 20030101

• Delayed methotrexate clearance in osteosarcoma patients treated with multiagent regimens of neoadjuvant chemotherapy.

  Oncology reports 20030101

• Combination of adenovirus-mediated thymidine kinase gene therapy with cytotoxic chemotherapy in bladder cancer in vitro.

  Urologic oncology 20030101

• [The assessment of plasma levels of insulin-like growth factor (IGF-I) and binding protein (IGFBP-3) during the maintenance therapy and after remissionof acute lymphoblastic leukemia (ALL)].

  Endokrynologia, diabetologia i choroby przemiany materii wieku rozwojowego : organ Polskiego Towarzystwa Endokrynologow Dzieciecych 20030101

• [The influence of age, gender and modifications of therapeutic protocols on physical development of children and adolescents after completion of therapy for acute lymphoblastic leukemia].

  Endokrynologia, diabetologia i choroby przemiany materii wieku rozwojowego : organ Polskiego Towarzystwa Endokrynologow Dzieciecych 20030101

• Treatment of early RA in clinical practice: a comparative study of two different DMARD/corticosteroid options.

  Clinical and experimental rheumatology 20030101

• Blood TNF-alpha and combination therapy for rheumatoid arthritis.

  Clinical and experimental rheumatology 20030101

• [Gold preparations in therapy of rheumatoid and psoriatic arthritis].

  Terapevticheskii arkhiv 20030101

• Membrane transport of folates.

  Vitamins and hormones 20030101

• Reduced folate carrier: biochemistry and molecular biology of the normal and methotrexate-resistant cell.

  British journal of biomedical science 20030101

• [The role of the conventional drugs in the treatment of rheumatoid arthritis].

  Recenti progressi in medicina 20030101

• [Kidney involvement in rheumatoid arthritis].

  Reumatismo 20030101

• Methotrexate intolerance in elderly patients with rheumatoid arthritis: what are the alternatives?

  Drugs & aging 20030101

• [Efficacy and safety of treatment with methotrexate, leflunomide, detralex, and their combination of patients with rheumatoid arthritis].

  Likars'ka sprava 20030101

• Comparison of antiproliferative effects of experimental and established antipsoriatic drugs on human keratinocytes, using a simple 96-well-plate assay.

  In vitro cellular & developmental biology. Animal 20030101

• Chemotherapy and antiangiogenesis--drug-specific, dose-related effects.

  Acta oncologica (Stockholm, Sweden) 20030101

• [Locoregional chemotherapy of locally advanced breast cancer in a pre-treated patient: case report].

  Tumori 20030101

• Immunosuppressive and cytotoxic therapy for pulmonary sarcoidosis.

  The Cochrane database of systematic reviews 20030101

• High dose methotrexate for ocular lesions of Behçet's disease. Preliminary short-term results.

  Advances in experimental medicine and biology 20030101

• Palliative chemotherapy after failure of high-dose chemotherapy in breast cancer--toxicity and efficacy.

  Anticancer research 20030101

• [Current concepts of pharmacotherapy in rheumatoid arthritis].

  Vestnik Rossiiskoi akademii meditsinskikh nauk 20030101

• Effect of different neoadjuvant chemotherapy regimens on locally advanced breast cancer.

  Neoplasma 20030101

• [Behçet's disease].

  Annales de dermatologie et de venereologie 20030101

• [Idiopathic hypereosinophilic syndrome associated with rheumatoid arthritis. A case report].

  Reumatismo 20030101

• [Improved results in children with acute lymphoblastic leukemia treated with the ALL-BFM 90 protocol in the Czech Republic].

  Casopis lekaru ceskych 20030101

• Fibroblastic rheumatism: a variant of non-Langerhans cell histiocytoses?

  Pediatric dermatology 20030101

• Drug targeting by macromolecules without recognition unit?

  Journal of molecular recognition : JMR 20030101

• Deaza analogs of folic acid as antitumor agents.

  Current pharmaceutical design 20030101

• Effect of retinoblastoma tumor suppressor gene expression on chemosensitivity of human osteosarcoma cell lines.

  Oncology reports 20030101

• Methotrexate for the treatment of unruptured tubal pregnancy: a prospective nonrandomized study.

  JSLS : Journal of the Society of Laparoendoscopic Surgeons 20030101

• Burkitt's lymphoma in the base of the tongue: differential diagnosis and management.

  ORL; journal for oto-rhino-laryngology and its related specialties 20030101

• 5-Fluorouracil, methotrexate, leucovorin, CDDP and epirubicin (FEPMTX): a wide-spectrum regimen of salvage chemotherapy for high-grade advanced gastric cancer.

  Hepato-gastroenterology 20030101

• Transition from methotrexate and cyclosporine to other therapies including retinoids, ultraviolet light and biologic agents in the management of patients with psoriasis.

  The Journal of dermatological treatment 20030101

• Case studies in severe psoriasis: A clinical strategy.

  The Journal of dermatological treatment 20030101

• [Innovative technologies in the complex treatment of patients with rheumatoid arthritis].

  Vestnik Rossiiskoi akademii meditsinskikh nauk 20030101

• [The modern organ- and function-sparing surgical treatment in oncology].

  Vestnik Rossiiskoi akademii meditsinskikh nauk 20030101

• Methotrexate inhibition of bone mineral density increase in growing rabbits: prevention by folinic acid.

  Clinical and experimental rheumatology 20030101

• Comprehensive nursing approach to infliximab infusion therapy.

  Journal of infusion nursing : the official publication of the Infusion Nurses Society 20030101

• [Neuro-Behçet's disease].

  Ryoikibetsu shokogun shirizu 20030101

• Homocysteine in patients with rheumatoid arthritis in relation to inflammation and B-vitamin treatment.

  Scandinavian journal of rheumatology 20030101

• Anaphylactoid reaction to carboplatin: successful 'desensitization'.

  Allergologia et immunopathologia 20030101

• Treatment of a pineal yolk sac tumor: report of one case.

  Acta paediatrica Taiwanica = Taiwan er ke yi xue hui za zhi 20030101

• Methylenetetrahydrofolate reductase gene polymorphism and glucocorticoid intake in children with ALL and aseptic osteonecrosis.

  Klinische Padiatrie 20030101

• Etanercept versus etanercept plus methotrexate: a registry-based study suggesting that the combination is clinically more efficacious.

  Arthritis research & therapy 20030101

• [Prognostication of hematotoxicity for radio- and chemotherapy in patients with breast cancer].

  Voprosy onkologii 20030101

• Medication sheets for patients. Oral chemotherapy.

  Clinical journal of oncology nursing 20030101

• Newer approaches to the treatment of rheumatoid arthritis.

  WMJ : official publication of the State Medical Society of Wisconsin 20030101

• Summated chemotherapy dose-intensity versus loco-regional response in locally advanced breast cancer: its possible implications.

  Indian journal of cancer 20030101

• Immunosuppressive antimetabolites inhibit induction of contact hypersensitivity while lymphoablative drugs also prevent its expression.

  European journal of dermatology : EJD 20030101

• Leflunomide improves the clinical response in patients with active rheumatoid arthritis treated with methotrexate.

  Clinical and experimental rheumatology 20030101

• The Utrecht experience with different treatment strategies in early rheumatoid arthritis.

  Clinical and experimental rheumatology 20030101

• Combination therapy in early rheumatoid arthritis.

  Clinical and experimental rheumatology 20030101

• Effect of antitumor agents on cytotoxicity induction by sodium fluoride.

  Anticancer research 20030101

• Early effects of different cytostatic protocols for head and neck cancer on oncogene activation in animal experiments.

  Anticancer research 20030101

• [Significantly improvement of antibody expression level in CHO cells through downregulation of the DHFR gene in expression vector].

  Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20030101

• Kynurenine and neopterin levels in patients with rheumatoid arthritis and osteoporosis during drug treatment.

  Advances in experimental medicine and biology 20030101

• [Efficacy of medical therapy in preventing the post-surgical recurrence in Crohn's disease].

  Annali italiani di chirurgia 20030101

• Correlation between methotrexate-induced intestinal damage and decrease in polyamine content.

  Life sciences 20021227

• Home care during the pancytopenic phase after allogeneic hematopoietic stem cell transplantation is advantageous compared with hospital care.

  Blood 20021215

• Adjuvant therapy for premenopausal women with breast cancer: is it time for another paradigm shift?

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20021215

• Randomized adjuvant trial of tamoxifen and goserelin versus cyclophosphamide, methotrexate, and fluorouracil: evidence for the superiority of treatment with endocrine blockade in premenopausal patients with hormone-responsive breast cancer--Austrian Breast and Colorectal Cancer Study Group Trial 5.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20021215

• Goserelin versus cyclophosphamide, methotrexate, and fluorouracil as adjuvant therapy in premenopausal patients with node-positive breast cancer: The Zoladex Early Breast Cancer Research Association Study.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20021215

• Combination chemotherapy and radiotherapy for primary central nervous system lymphoma: Radiation Therapy Oncology Group Study 93-10.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20021215

• Block sequential adriamycin CMF--optimal non-myeloablative chemotherapy for high risk adjuvant breast cancer?

  British journal of cancer 20021202

• Methotrexate-induced optic neuropathy.

  Clinical & experimental ophthalmology 20021201

• Clinical trials for pediatric scleroderma.

  Current rheumatology reports 20021201

• Purine enzymes in patients with rheumatoid arthritis treated with methotrexate.

  Annals of the rheumatic diseases 20021201

• Intra-arterial catheter directed therapy for severe graft-versus-host disease.

  British journal of haematology 20021201

• Successful non-T cell-depleted HLA haplo-identical three-loci mismatched hematopoietic stem cell transplantation from mother to son based on the feto-maternal microchimerism in chronic myelogenous leukemia.

  Bone marrow transplantation 20021201

• Advances in medical therapy for Crohn's disease.

  Current gastroenterology reports 20021201

• Thymidylate synthase protein expression in colorectal cancer metastases predicts for clinical outcome to leucovorin-modulated bolus or infusional 5-fluorouracil but not methotrexate-modulated bolus 5-fluorouracil.

  Annals of oncology : official journal of the European Society for Medical Oncology 20021201

• Preponderance of methylenetetrahydrofolate reductase C677T homozygosity among leukemia patients intolerant to methotrexate.

  Annals of oncology : official journal of the European Society for Medical Oncology 20021201

• A pilot study of short-course intensive multiagent chemotherapy in metastatic and axial skeletal osteosarcoma.

  Annals of oncology : official journal of the European Society for Medical Oncology 20021201

• Role of the E45K-reduced folate carrier gene mutation in methotrexate resistance in human leukemia cells.

  Leukemia 20021201

• Contemporary disease modifying antirheumatic drugs (DMARD) in patients with recent onset rheumatoid arthritis in a US private practice: methotrexate as the anchor drug in 90% and new DMARD in 30% of patients.

  The Journal of rheumatology 20021201

• Eosinophilia, arthritis, and soft tissue swellings.

  The Journal of rheumatology 20021201

• Case of PSTT treated with chemotherapy followed by open uterine tumor resection to preserve fertility.

  Gynecologic oncology 20021201

• The rheumatoid arthritis patient in the clinic: comparing more than 1,300 consecutive DMARD courses.

  Rheumatology (Oxford, England) 20021201

• Anti-tumour necrosis factor therapy associated with cutaneous vasculitis.

  Rheumatology (Oxford, England) 20021201

• G-CSF-primed haploidentical marrow transplantation without ex vivo T cell depletion: an excellent alternative for high-risk leukemia.

  Bone marrow transplantation 20021201

• Effect of chronic methanol administration on amino acids and monoamines in retina, optic nerve, and brain of the rat.

  Toxicology and applied pharmacology 20021201

• [Immunosuppressive medication in multiple sclerosis].

  Revista de neurologia 20021201

• Monitoring of methotrexate and reduced folates in the cerebrospinal fluid of cancer patients.

  International journal of clinical pharmacology and therapeutics 20021201

• [Recent advance in adjuvant therapy for breast cancer].

  Gan to kagaku ryoho. Cancer & chemotherapy 20021201

• [A patient with mantle cell lymphoma who successfully underwent auto-PBSCT in combination with in vivo purging of tumor cells using rituximab].

  Gan to kagaku ryoho. Cancer & chemotherapy 20021201

• [Methotrexate for the treatment of rheumatoid arthritis in Japan--much more still remains to be resolved].

  Nihon rinsho. Japanese journal of clinical medicine 20021201

• [Pharmacogenetics of disease modifying anti-rheumatic drugs].

  Nihon rinsho. Japanese journal of clinical medicine 20021201

• [Clinical implication of cyclosporin for rheumatoid arthritis].

  Nihon rinsho. Japanese journal of clinical medicine 20021201

• [Combination therapy of disease-modifying antirheumatic drugs(DMARDs) in rheumatoid arthritis].

  Nihon rinsho. Japanese journal of clinical medicine 20021201

• [Efficacy of leflunomide].

  Nihon rinsho. Japanese journal of clinical medicine 20021201

• Coeliac disease following high-dose chemotherapy.

  Clinical oncology (Royal College of Radiologists (Great Britain)) 20021201

• Pasteurella multocida infection in a post-chemotherapy neutropenic host following cat exposure.

  Clinical oncology (Royal College of Radiologists (Great Britain)) 20021201

• Optimal therapy of primary ocular lymphoma.

  Clinical oncology (Royal College of Radiologists (Great Britain)) 20021201

• [Primary study on establishment of namalwa 12/MTX resistant cell strain and its mechanism].

  Ai zheng = Aizheng = Chinese journal of cancer 20021201

• Challenges in the management of Burkitt's lymphoma.

  Clinical lymphoma 20021201

• Epidemiology of Burkitt's lymphoma in Enugu, Nigeria.

  Annals of tropical paediatrics 20021201

• In vitro human scleral permeability of fluorescein, dexamethasone-fluorescein, methotrexate-fluorescein and rhodamine 6G and the use of a coated coil as a new drug delivery system.

  Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20021201

• Molecular, biochemical, and cellular pharmacology of pemetrexed.

  Seminars in oncology 20021201

• Etoposide, doxorubicin and cisplatin alternating with 5-fluorouracil, doxorubicin and high-dose methotrexate in patients with advanced adenocarcinoma of the stomach or the gastroesophageal junction.

  Journal of chemotherapy (Florence, Italy) 20021201

• Decreased hepatobiliary transport of methotrexate in adjuvant arthritis rats.

  Xenobiotica; the fate of foreign compounds in biological systems 20021201

• Treatment of refractory Churg-Strauss-Syndrome (CSS) by TNF-alpha blockade.

  Immunobiology 20021201

• Pharmacodynamic modeling of chemotherapeutic effects: application of a transit compartment model to characterize methotrexate effects in vitro.

  AAPS pharmSci 20021201

• Epstein-Barr virus-associated lymphoproliferative disorder in a patient with rheumatoid arthritis on methotrexate and rofecoxib: idiosyncratic reaction or pharmacogenetics?

  Delaware medical journal 20021201

• Polymorphism G80A in the reduced folate carrier gene and its relationship to methotrexate plasma levels and outcome of childhood acute lymphoblastic leukemia.

  Blood 20021115

• Can cure in patients with osteosarcoma be achieved exclusively with chemotherapy and abrogation of surgery?

  Cancer 20021115

• A novel folate transport activity in human mesothelioma cell lines with high affinity and specificity for the new-generation antifolate, pemetrexed.

  Cancer research 20021115

• [The effect of comedication with folic or folinic acid on the toxicity and efficacy of methotrexate in rheumatoid arthritis: a randomized, double blind, placebo controlled study of 48 weeks].

  Nederlands tijdschrift voor geneeskunde 20021109

• Synthesis of classical and nonclassical, partially restricted, linear, tricyclic 5-deaza antifolates.

  Journal of medicinal chemistry 20021107

• Concomitant leflunomide therapy in patients with active rheumatoid arthritis despite stable doses of methotrexate. A randomized, double-blind, placebo-controlled trial.

  Annals of internal medicine 20021105

• Summaries for patients. Combination therapy for rheumatoid arthritis.

  Annals of internal medicine 20021105

• Remission of lymphoma after drug withdrawal in rheumatoid arthritis.

  The Medical journal of Australia 20021104

• Resistance to multiple novel antifolates is mediated via defective drug transport resulting from clustered mutations in the reduced folate carrier gene in human leukaemia cell lines.

  The Biochemical journal 20021101

• Charged amino acids in the sixth transmembrane helix of multidrug resistance protein 1 (MRP1/ABCC1) are critical determinants of transport activity.

  The Journal of biological chemistry 20021101

• Nonmyeloablative transplantation with or without alemtuzumab: comparison between 2 prospective studies in patients with lymphoproliferative disorders.

  Blood 20021101

• Induction therapy with idarubicin alone significantly influences event-free survival duration in patients with newly diagnosed hypergranular acute promyelocytic leukemia: final results of the GIMEMA randomized study LAP 0389 with 7 years of minimal follow-up.

  Blood 20021101

• Inhibition of the multidrug resistance protein 1 (MRP1) by peptidomimetic glutathione-conjugate analogs.

  Molecular pharmacology 20021101

• Early changes in [18F]FLT uptake after chemotherapy: an experimental study.

  European journal of nuclear medicine and molecular imaging 20021101

• Improvement over time in outcome for children with acute lymphoblastic leukemia in second remission given hematopoietic stem cell transplantation from unrelated donors.

  Leukemia 20021101

• Prospective molecular monitoring of BCR/ABL transcript in children with Ph+ acute lymphoblastic leukaemia unravels differences in treatment response.

  British journal of haematology 20021101

• Role of LHRH agonists in premenopausal women with oestrogen receptor-positive breast cancer: the ZEBRA experience.

  European journal of cancer (Oxford, England : 1990) 20021101

• Unusual sites of involvement in non-Hodgkin's lymphoma: Case 2. Isolated meningeal anaplastic large-cell lymphoma.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20021101

• Prevention of autoimmune attack and disease progression in multiple sclerosis: current therapies and future prospects.

  Internal medicine journal 20021101

• A dexamethasone, vinblastine, cyclophosphamide, etoposide, methotrexate and bleomycin (D-VICEMB) protocol as first-line treatment of patients aged 70 years or older affected by intermediate/high grade non-Hodgkin's lymphoma.

  Haematologica 20021101

• Churg-Strauss syndrome: clinical and serological features of 19 patients from a single Italian centre.

  Rheumatology (Oxford, England) 20021101

• Association of baseline levels of markers of bone and cartilage degradation with long-term progression of joint damage in patients with early rheumatoid arthritis: the COBRA study.

  Arthritis and rheumatism 20021101

• [Gastrointestinal side effects in the therapy of rheumatologic diseases].

  Zeitschrift fur Gastroenterologie 20021101

• Tailored chemotherapy for malignant lymphoma arising in the setting of posttransplant lymphoproliferative disorder after solid organ transplantation.

  Journal of pediatric hematology/oncology 20021101

• Methotrexate polyglutamation may lack prognostic significance in children with B-cell precursor acute lymphoblastic leukemia treated with intensive oral methotrexate.

  Journal of pediatric hematology/oncology 20021101

• A mathematical model of in vivo methotrexate accumulation in acute lymphoblastic leukemia.

  Cancer chemotherapy and pharmacology 20021101

• Epirubicin versus CMF as adjuvant therapy for stage I and II breast cancer: a prospective randomised study.

  European journal of cancer (Oxford, England : 1990) 20021101

• Coexisting true hermaphroditism and partial hydatidiform mole developing metastatic gestational trophoblastic tumors. A case report.

  Virchows Archiv : an international journal of pathology 20021101

• Long-term follow-up of allogeneic stem cell transplantation in patients with severe aplastic anemia after conditioning with cyclophosphamide plus antithymocyte globulin.

  Annals of hematology 20021101

• Treatment outcome of adolescents with acute lymphoblastic leukemia.

  Annals of hematology 20021101

• Photohydrolysis of methotrexate produces pteridine, which induces poly-G-specific DNA damage through photoinduced electron transfer.

  Photochemistry and photobiology 20021101

• Vitamin D and systemic therapy.

  Cutis 20021101

• [A case of pyloric or antral malignant stenosis treated with arterial infusion chemotherapy and palliative therapy--self-expandable metal stents through gastrostomy].

  Gan to kagaku ryoho. Cancer & chemotherapy 20021101

• [A case of gastric cancer associated with synchronous liver metastasis successfully treated with combination therapy of systemic and hepatic arterial infusion chemotherapy].

  Gan to kagaku ryoho. Cancer & chemotherapy 20021101

• Methotrexate-related neurotoxicity in the treatment of childhood acute lymphoblastic leukemia.

  The Israel Medical Association journal : IMAJ 20021101

• Hippocampal brain amines in methotrexate-induced learning and memory deficit.

  Canadian journal of physiology and pharmacology 20021101

• Delays in diagnosing breast cancer--the impact of concurrent pregnancy and lactation.

  The Australian & New Zealand journal of obstetrics & gynaecology 20021101

• [Behcet's disease therapy review].

  Anales de medicina interna (Madrid, Spain : 1984) 20021101

• Carboxypeptidase-G2 rescue in cancer patients with delayed methotrexate elimination after high-dose methotrexate therapy.

  Leukemia & lymphoma 20021101

• [Analysis of efficacy and safety of multiple intravenous infusion of anti-tumor necrosis factor-alpha monoclonal antibody (Remicade) combined with methotrexate compared with sodium aurothiomalate and intramuscular depot methylprednisolone in rheumatoid arthritis].

  Polskie Archiwum Medycyny Wewnetrznej 20021101

• Amplification using CHO cell expression vectors.

  Current protocols in molecular biology 20021101

• Methotrexate treatment and mortality in rheumatoid arthritis.

  Lancet (London, England) 20021005

• Azathioprine or methotrexate in the treatment of patients with steroid-dependent or steroid-resistant ulcerative colitis: results of an open-label study on efficacy and tolerability in inducing and maintaining remission.

  Alimentary pharmacology & therapeutics 20021001

• Aggressive management of juvenile dermatomyositis results in improved outcome and decreased incidence of calcinosis.

  Journal of the American Academy of Dermatology 20021001

• Identification of a novel human organic anion transporting polypeptide as a high affinity thyroxine transporter.

  Molecular endocrinology (Baltimore, Md.) 20021001

• Rescue of combination therapy failures using infliximab, while maintaining the combination or monotherapy with methotrexate: results of an open trial.

  Rheumatology (Oxford, England) 20021001

• Therapy-induced leukemias and myelodysplastic syndromes after breast cancer treatment: an underemphasized clinical problem.

  Annals of surgical oncology 20021001

• Characterization of a novel metabolic strategy used by drug-resistant tumor cells.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20021001

• Methotrexate: vital new information about a middle aged drug.

  The Journal of rheumatology 20021001

• Combination therapy with methotrexate and hydroxychloroquine for rheumatoid arthritis increases exposure to methotrexate.

  The Journal of rheumatology 20021001

• Longitudinal measurement of methotrexate liver concentrations does not correlate with liver damage, clinical efficacy, or toxicity during a 3.5 year double blind study in rheumatoid arthritis.

  The Journal of rheumatology 20021001

• Effective removal of methotrexate by high-flux hemodialysis.

  Pediatric nephrology (Berlin, Germany) 20021001

• CMF (cyclophosphamide, methotrexate, 5-fluorouracil) versus CNF (cyclophosphamide, mitoxantrone, 5-fluorouracil) as adjuvant chemotherapy for stage II lymph-node positive breast cancer: results by demographic and clinical subgroups.

  American journal of clinical oncology 20021001

• [Psoriatic onycho-pachydermo- periostitis].

  Zeitschrift fur Rheumatologie 20021001

• Combination of ifosfamide, methotrexate, and etoposide (IMVP) as a salvage therapy for relapsed and refractory aggressive non-Hodgkin lymphoma: retrospective study.

  Croatian medical journal 20021001

• Intralesional corticosteroid treatment of multiple eruptive keratoacanthomas: case report and review of a controversial therapy.

  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20021001

• Chemotherapy for breast cancer brain metastases.

  Onkologie 20021001

• Severe immune hemolysis after minor ABO-mismatched allogeneic peripheral blood progenitor cell transplantation occurs more frequently after nonmyeloablative than myeloablative conditioning.

  Transfusion 20021001

• Epstein-Barr virus-associated lymphoproliferative disease occurring in a patient with sarcoidosis treated by methotrexate and methylprednisolone.

  European journal of haematology 20021001

• Adjuvant chemotherapy for deep muscle-invasive transitional cell bladder carcinoma - a practice guideline.

  The Canadian journal of urology 20021001

• Dimerizer-regulated gene expression.

  Current opinion in biotechnology 20021001

• Traditional therapies: glucocorticoids, azathioprine, methotrexate, hydroxyurea.

  Clinical and experimental dermatology 20021001

• Effects of methotrexate upon inflammatory parameters induced by carrageenan in the mouse model of pleurisy.

  Mediators of inflammation 20021001

• Chemosensitization of carmustine with maitake beta-glucan on androgen-independent prostatic cancer cells: involvement of glyoxalase I.

  Journal of alternative and complementary medicine (New York, N.Y.) 20021001

• System approach to modeling metabolite formation from parent drug: a working example with methotrexate.

  Methods and findings in experimental and clinical pharmacology 20021001

• The application of electroporation to transfect hematopoietic cells and to deliver drugs and vaccines transcutaneously for cancer treatment.

  Technology in cancer research & treatment 20021001

• Involvement of the peripheral benzodiazepine receptor in the development of rheumatoid arthritis in Mrl/lpr mice.

  European journal of pharmacology 20020927

• The murine-reduced folate carrier gene can act as a selectable marker and a suicide gene in hematopoietic cells in vivo.

  Human gene therapy 20020920

• An animal model for the study of chronopharmacokinetics of drugs and application to methotrexate and vinorelbine.

  Toxicology and applied pharmacology 20020915

• [How long should cyclophosphamide therapy of Wegener's granulomatosis continue?].

  Deutsche medizinische Wochenschrift (1946) 20020913

• [Corticosteroid saving-up in giant cell arteritis?].

  Deutsche medizinische Wochenschrift (1946) 20020913

• Receptor-dependence of the transcription read-out in a small-molecule three-hybrid system.

  Chembiochem : a European journal of chemical biology 20020902

• Loss of heterozygosity of p16 correlates with minimal residual disease at the end of the induction therapy in non-high risk childhood B-cell precursor acute lymphoblastic leukemia.

  Leukemia research 20020901

• Therapeutic options for sarcoidosis: new and old.

  Current opinion in pulmonary medicine 20020901

• Soluble HLA-DR levels in serum are associated with therapy and genetic factors in rheumatoid arthritis.

  Human immunology 20020901

• The role of posttransplantation maintenance chemotherapy in improving the outcome of autotransplantation in adult acute lymphoblastic leukemia.

  Blood 20020901

• Long-term outcome of neoadjuvant therapy for locally advanced breast carcinoma: effective clinical downstaging allows breast preservation and predicts outstanding local control and survival.

  Annals of surgery 20020901

• Pharmacodynamics of high-dose methotrexate in pediatric patients.

  The Annals of pharmacotherapy 20020901

• Late effects of adjuvant chemotherapy on cognitive function: a follow-up study in breast cancer patients.

  Annals of oncology : official journal of the European Society for Medical Oncology 20020901

• Pityriasis rubra pilaris in children.

  Journal of the American Academy of Dermatology 20020901

• Schedule-dependent synergism and antagonism between methotrexate and cytarabine against human leukemia cell lines in vitro.

  Leukemia 20020901

• Long-term results (12 years) of high-dose therapy in 127 patients with de novo multiple myeloma.

  Leukemia 20020901

• Therapy-related myelodysplastic syndrome or acute myelogenous leukemia in patients with acute promyelocytic leukemia (APL).

  Leukemia 20020901

• Ex vivo stimulation of renal transport of the cytostatic drugs methotrexate, cisplatin, topotecan (Hycamtin) and raltitrexed (Tomudex) by dexamethasone, T3 and EGF in intact human and rat kidney tissue and in human renal cell carcinoma.

  Urological research 20020901

• Local recurrence in the breast after conservative surgery--a study of prognosis and prognostic factors in 391 women.

  European journal of cancer (Oxford, England : 1990) 20020901

• Overexpression of wild-type breast cancer resistance protein mediates methotrexate resistance.

  Cancer research 20020901

• Bilateral recurrent focal myositis of gastrocnemius muscles after BCG vaccination.

  Rheumatology (Oxford, England) 20020901

• Neoadjuvant chemotherapy followed by salvage surgery: effect on survival of patients with primary noncurative gastric cancer.

  World journal of surgery 20020901

• Protection of the Peyer's patch-associated crypt and villus epithelium against methotrexate-induced damage is based on its distinct regulation of proliferation.

  The Journal of pathology 20020901

• Activity of postoperative carboplatin, etoposide, and high-dose methotrexate in pediatric CNS embryonal tumors: results of a phase II study in newly diagnosed children.

  Medical and pediatric oncology 20020901

• Outcome of B-cell non-Hodgkin lymphoma protocol CCCG-B NHL97: a report from Chinese multi-center cooperative group.

  Medical and pediatric oncology 20020901

• Effect of methotrexate on pulmonary function in patients with rheumatoid arthritis--a prospective study.

  Rheumatology international 20020901

• A successful second unrelated BMT (UBMT) from a different unrelated donor to treat ALL that relapsed after the initial UBMT.

  American journal of hematology 20020901

• Central nervous system relapse in acute promyelocytic leukemia.

  American journal of hematology 20020901

• A review of methotrexate-induced accelerated nodulosis.

  Pharmacotherapy 20020901

• Methotrexate-induced toxic leukoencephalopathy.

  Pharmacotherapy 20020901

• [Non-steroid therapy for sarcoidosis].

  Nihon rinsho. Japanese journal of clinical medicine 20020901

• Tumor necrosis factor-alpha receptor II polymorphism in patients from southern Europe with mild-moderate and severe rheumatoid arthritis.

  The Journal of rheumatology 20020901

• Combination chemotherapy with high-dose methotrexate and cytarabine with or without brain irradiation for primary central nervous system lymphomas.

  Journal of neuro-oncology 20020901

• Pathologic changes related to CMF primary chemotherapy in breast cancer. Pathological evaluation of response predicts clinical outcome.

  Breast cancer research and treatment 20020901

• [Chemotherapy of gastric cancer--a review of clinical trials in Japan].

  Gan to kagaku ryoho. Cancer & chemotherapy 20020901

• Intrathecal chemotherapy alone is inadequate central nervous system prophylaxis in patients with intermediate-grade non-Hodgkin's lymphoma.

  Leukemia & lymphoma 20020901

• [Alcohol and patients with gout].

  Ugeskrift for laeger 20020826

• A new type of high affinity folic acid transporter in the protozoan parasite Leishmania and deletion of its gene in methotrexate-resistant cells.

  The Journal of biological chemistry 20020816

• De novo purine synthesis inhibition and antileukemic effects of mercaptopurine alone or in combination with methotrexate in vivo.

  Blood 20020815

• Expression and activity of the DNA repair enzyme uracil DNA glycosylase during organogenesis in the rat conceptus and following methotrexate exposure in vitro.

  Biochemical pharmacology 20020815

• Effects of antirheumatic therapy on serum lipid levels in patients with rheumatoid arthritis: a prospective study.

  The American journal of medicine 20020815

• Concurrent cyclophosphamide, methotrexate, and 5-fluorouracil chemotherapy and radiotherapy for breast carcinoma: a well tolerated adjuvant regimen.

  Cancer 20020815

• Biological monitoring of hospital personnel occupationally exposed to antineoplastic agents.

  Toxicology letters 20020805

• Changes in BRCA1 and BRCA2 expression produced by chemotherapeutic agents in human breast cancer cells.

  The international journal of biochemistry & cell biology 20020801

• Optical biosensors for real-time measurement of analytes in blood plasma.

  Biosensors & bioelectronics 20020801

• Reversible vincristine-related flaccid paralysis in a child with acute lymphoblastic leukemia.

  Medical and pediatric oncology 20020801

• Characterization of methotrexate transport and its drug interactions with human organic anion transporters.

  The Journal of pharmacology and experimental therapeutics 20020801

• Primary granulocytic sarcoma of the urinary bladder: case report and review of the literature.

  Urology 20020801

• Multiple bilateral eyelid molluscum contagiosum lesions associated with TNFalpha-antibody and methotrexate therapy.

  American journal of ophthalmology 20020801

• Pharmacokinetic interaction between high-dose methotrexate and oxacillin.

  Therapeutic drug monitoring 20020801

• Homology modeling and docking mechanism of the mercaptosuccinate and methotrexate to P. falciparum 1-Cys peroxiredoxin: a preliminary molecular study.

  Journal of biomolecular structure & dynamics 20020801

• Ribonucleotide reductase and thymidine phosphorylation: two potential targets of azodicarbonamide.

  Biochemical pharmacology 20020801

• Mycophenolate mofetil for systemic lupus erythematosus refractory to other immunosuppressive agents.

  Rheumatology (Oxford, England) 20020801

• Analysis of improvements, full responses, remission and toxicity in rheumatoid patients treated with step-up combination therapy (methotrexate, cyclosporin A, sulphasalazine) or monotherapy for three years.

  Rheumatology (Oxford, England) 20020801

• The effects of disease-modifying anti-rheumatic drugs on the Health Assessment Questionnaire score. Lessons from the leflunomide clinical trials database.

  Rheumatology (Oxford, England) 20020801

• A case of treatment-related myelodysplastic syndrome and acute myelogenous leukemia following high-dose chemotherapy with autologous stem cell transplantation for non-Hodgkin's lymphoma.

  Journal of Korean medical science 20020801

• Osteosarcoma cells, resistant to methotrexate due to nucleoside and nucleobase salvage, are sensitive to nucleoside analogs.

  Cancer chemotherapy and pharmacology 20020801

• Not yet time to change the guidelines for monitoring methotrexate liver toxicity: they have served us well.

  The Journal of rheumatology 20020801

• Hyperhomocysteinemia in rheumatoid arthritis: influence of methotrexate treatment and folic acid supplementation.

  The Journal of rheumatology 20020801

• Methotrexate, hydroxychloroquine, and intramuscular gold in rheumatoid arthritis: relative area under the curve effectiveness and sequence effects.

  The Journal of rheumatology 20020801

• Severe cardiac involvement in children with systemic sclerosis and myositis.

  The Journal of rheumatology 20020801

• An international evaluation of CODOX-M and CODOX-M alternating with IVAC in adult Burkitt's lymphoma: results of United Kingdom Lymphoma Group LY06 study.

  Annals of oncology : official journal of the European Society for Medical Oncology 20020801

• Inflammatory bowel disease: sorting out the treatment options.

  Cleveland Clinic journal of medicine 20020801

• Chemosensitivity of normal human trophoblasts evaluated by a newly developed ATP-based luminescence assay.

  Anti-cancer drugs 20020801

• Chemotherapy in the post-MVAC era: the case for adjuvant chemotherapy.

  World journal of urology 20020801

• New drugs and new approaches for the treatment of metastatic urothelial cancer.

  World journal of urology 20020801

• A case of intravenous immunoglobulin-resistant Kawasaki disease treated with methotrexate.

  Yonsei medical journal 20020801

• Efficacy of tacrolimus in rheumatoid arthritis patients who have been treated unsuccessfully with methotrexate: a six-month, double-blind, randomized, dose-ranging study.

  Arthritis and rheumatism 20020801

• Prophylactic intrathecal methotrexate and hydrocortisone reduces central nervous system recurrence and improves survival in aggressive non-hodgkin lymphoma.

  Cancer 20020801

• Fetal methotrexate and misoprostol exposure: the past revisited.

  Teratology 20020801

• Simultaneous analysis of sulfur-containing excitatory amino acids using micellar electrokinetic chromatography with diode array and laser-induced fluorescence detection.

  Electrophoresis 20020801

• [Gestational trophoblastic tumors and recent clinical information].

  Gan to kagaku ryoho. Cancer & chemotherapy 20020801

• Natural killer cells contribute to the lethality of a murine model of Escherichia coli infection.

  Surgery 20020801

• Comparative antiproliferative effects of (111)In-DTPA-hEGF, chemotherapeutic agents and gamma-radiation on EGFR-positive breast cancer cells.

  Nuclear medicine and biology 20020801

• Evolving new therapies of autoimmune hepatitis.

  Clinics in liver disease 20020801

• A case of advanced esophageal cancer with extensive lymph node metastases successfully treated with multimodal therapy.

  Japanese journal of clinical oncology 20020801

• [Gemcitabine and urogenital tumors].

  Bulletin du cancer 20020801

• [Clinical observation on treatment of rheumatoid arthritis by combined therapy with methotrexate, sulfasalazine and Chinese herbal medicine].

  Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20020801

• Contribution of meta-analyses to the evaluation of treatments for advanced colorectal cancer.

  Expert review of anticancer therapy 20020801

• [Methotrexate therapy for rheumatism and collagen diseases].

  Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology 20020801

• Kinetic fluorimetric determination of the antineoplastic methotrexate (MTX) in human serum.

  Journal of pharmaceutical and biomedical analysis 20020731

• Combination of tacrolimus, methotrexate, and methylprednisolone prevents acute but not chronic graft-versus-host disease in unrelated bone marrow transplantation.

  Transplantation 20020727

• Conformational remodeling of proteasomal substrates by PA700, the 19 S regulatory complex of the 26 S proteasome.

  The Journal of biological chemistry 20020726

• A synthetic analog of prostaglandin E(1) prevents the production of reactive oxygen species in the intestinal mucosa of methotrexate-treated rats.

  Life sciences 20020719

• Novel aspects of resistance to drugs targeted to dihydrofolate reductase and thymidylate synthase.

  Biochimica et biophysica acta 20020718

• Endocrine responsiveness and tailoring adjuvant therapy for postmenopausal lymph node-negative breast cancer: a randomized trial.

  Journal of the National Cancer Institute 20020717

• VAMP and low-dose, involved-field radiation for children and adolescents with favorable, early-stage Hodgkin's disease: results of a prospective clinical trial.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020715

• Inhibition of heparin synthesis by methotrexate in rats in vivo.

  Biochemical pharmacology 20020715

• Randomized trial comparing cyclophosphamide, methotrexate, and 5-fluorouracil (CMF) with rotational CMF, epirubicin and vincristine as primary chemotherapy in operable breast carcinoma.

  Cancer 20020715

• Intrathecal methotrexate affects cognitive function in children with medulloblastoma.

  Neurology 20020709

• [Complicated antiphospholid antibody syndrome].

  Deutsche medizinische Wochenschrift (1946) 20020705

• A bacterial small-molecule three-hybrid system.

  Angewandte Chemie (International ed. in English) 20020702

• CD56 expression predicts occurrence of CNS disease in acute lymphoblastic leukemia.

  Leukemia research 20020701

• Leptomeningeal relapse of multiple myeloma following allogeneic stem cell transplantation.

  Leukemia research 20020701

• CYP3A4 induction by drugs: correlation between a pregnane X receptor reporter gene assay and CYP3A4 expression in human hepatocytes.

  Drug metabolism and disposition: the biological fate of chemicals 20020701

• Alpha(4)beta(7)/alpha(4)beta(1) dual integrin antagonists block alpha(4)beta(7)-dependent adhesion under shear flow.

  The Journal of pharmacology and experimental therapeutics 20020701

• Isolation, characterization and differential gene expression of multispecific organic anion transporter 2 in mice.

  Molecular pharmacology 20020701

• Transforming Growth Factor-beta2 protects the small intestine during methotrexate treatment in rats possibly by reducing stem cell cycling.

  British journal of cancer 20020701

• Methotrexate in the treatment of rheumatoid arthritis. II. In vivo effects on bone mineral density.

  Rheumatology (Oxford, England) 20020701

• Comparison of UV derivative-spectrophotometry and partial least-squares (PLS-1) calibration for determination of methotrexate and leucovorin in biological fluids.

  Analytical and bioanalytical chemistry 20020701

• Methotrexate intracellular disposition in acute lymphoblastic leukemia: a mathematical model of gamma-glutamyl hydrolase activity.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20020701

• Progression elevated gene-3, PEG-3, induces genomic instability in rodent and human tumor cells.

  Journal of cellular physiology 20020701

• Symptomatic hypoglycemia in children receiving oral purine analogues for treatment of childhood acute lymphoblastic leukemia.

  Medical and pediatric oncology 20020701

• Variant translocations of 11q23 in infant acute lymphoblastic leukemia (ALL): do outcomes differ from t(4;11)?

  Medical and pediatric oncology 20020701

• Increased factor VIII activity and dural sinus thrombosis.

  Medical and pediatric oncology 20020701

• Central nervous system lesions in adult T-cell leukaemia: MRI and pathology.

  Neuroradiology 20020701

• Giant cell arteritis complicated by spinal cord infarction: a therapeutic dilemma.

  The Journal of rheumatology 20020701

• Disseminated cryptococcal infection in rheumatoid arthritis treated with methotrexate and infliximab.

  The Journal of rheumatology 20020701

• [Tubulointerstitial nephritis and uveitis (TINU syndrome) - comorbidity and complications in four patients].

  Klinische Monatsblatter fur Augenheilkunde 20020701

• Advanced therapy for juvenile arthritis.

  Best practice & research. Clinical rheumatology 20020701

• Drug points: Severe myalgia from an interaction between treatments with pantoprazole and methotrexate.

  BMJ (Clinical research ed.) 20020622

• Tumour microvessel density as predictor of chemotherapy response in breast cancer patients.

  British journal of cancer 20020617

• Intensive, very short-term chemotherapy for advanced Burkitt's lymphoma in children.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020615

• Medication toxicity among patients with ankylosing spondylitis.

  Arthritis and rheumatism 20020615

• Physician treatment preferences in rheumatoid arthritis of differing disease severity and activity: the impact of cost on first-line therapy.

  Arthritis and rheumatism 20020615

• High rate of renal relapse in 71 patients with Wegener's granulomatosis under maintenance of remission with low-dose methotrexate.

  Arthritis and rheumatism 20020615

• Duration of adjuvant chemotherapy for breast cancer: a joint analysis of two randomised trials investigating three versus six courses of CMF.

  British journal of cancer 20020605

• Reduced folate carrier transports thiamine monophosphate: an alternative route for thiamine delivery into mammalian cells.

  American journal of physiology. Cell physiology 20020601

• Differences between children and adults in thiopurine methyltransferase activity and metabolite formation during thiopurine therapy: possible role of concomitant methotrexate.

  Therapeutic drug monitoring 20020601

• Sarcomatoid variant of anaplastic large cell lymphoma mimicking a primary breast cancer: a challenging diagnosis.

  Archives of pathology & laboratory medicine 20020601

• Analysis of methotrexate and folate transport by multidrug resistance protein 4 (ABCC4): MRP4 is a component of the methotrexate efflux system.

  Cancer research 20020601

• Homocysteine and folate status in methotrexate-treated patients with rheumatoid arthritis.

  Rheumatology (Oxford, England) 20020601

• Anaplastic large cell lymphoma in childhood: analysis of 72 patients treated on The United Kingdom Children's Cancer Study Group chemotherapy regimens.

  British journal of haematology 20020601

• Factors affecting long-term outcome after allogeneic haematopoietic stem cell transplantation for acute myelogenous leukaemia: a retrospective study of 172 adult patients reported to the Austrian Stem Cell Transplantation Registry.

  British journal of haematology 20020601

• Changes in microvessel density as assessed by CD34 antibodies after primary chemotherapy in human breast cancer.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20020601

• A cost effectiveness analysis of treatment options for methotrexate-naive rheumatoid arthritis.

  The Journal of rheumatology 20020601

• Cutaneous metastasis of gestational choriocarcinoma.

  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20020601

• Oral methotrexate for treatment of ectopic pregnancy.

  American journal of obstetrics and gynecology 20020601

• Folinic acid antagonizes methotrexate-induced differentiation of monocyte progenitors.

  Rheumatology international 20020601

• Polyarteritis nodosa presenting as polymyositis.

  Seminars in arthritis and rheumatism 20020601

• Bayesian population model of methotrexate to guide dosage adjustments for folate rescue in patients with breast cancer.

  Journal of clinical pharmacy and therapeutics 20020601

• Management of brain metastases in patients with high-risk gestational trophoblastic tumors.

  The Journal of reproductive medicine 20020601

• The present and future of combination chemotherapy in bladder cancer.

  Seminars in oncology 20020601

• [A patient with febrile and lymphatic hyperalgesia on returning from the tropics].

  La Revue de medecine interne 20020601

• Antiproliferative-antiinflammatory effects of methotrexate and sex hormones on cultured differentiating myeloid monocytic cells (THP-1).

  Annals of the New York Academy of Sciences 20020601

• In utero first trimester exposure to low-dose methotrexate with increased fetal nuchal translucency and associated malformations.

  Prenatal diagnosis 20020601

• Addition of either irinotecan or methotrexate to bolus 5-fluorouracil and high-dose folinic acid every 2 weeks in advanced colorectal carcinoma: a randomised study by the Southern Italy Cooperative Oncology Group.

  Annals of oncology : official journal of the European Society for Medical Oncology 20020601

• Detection and monitoring of methotrexate-associated lung injury using serum markers KL-6 and SP-D in rheumatoid arthritis.

  Internal medicine (Tokyo, Japan) 20020601

• [A case of cutaneous tuberculosis under steroid & immunosuppressant therapy for dermatomyositis].

  Kekkaku : [Tuberculosis] 20020601

• [Primary cardiac lymphoma: cytological diagnosis and treatment with response to polychemotherapy and hematopoietic precursor autotransplant. Presentation of a case a review of the literature].

  Anales de medicina interna (Madrid, Spain : 1984) 20020601

• Methotrexate induced seizures associated with acute reversible magnetic resonance imaging (MRI) changes in a patient with acute lymphoblastic leukemia.

  Leukemia & lymphoma 20020601

• Quantitative assessment of the clavicle radiostructure as a tool for estimation of the osteopathic effect of breast cancer chemotherapy.

  Breast cancer research and treatment 20020601

• Weight gain in women with breast cancer treated with adjuvant cyclophosphomide, methotrexate and 5-fluorouracil. Analysis of resting energy expenditure and body composition.

  Breast cancer research and treatment 20020601

• The role of combined method in organ-sparing treatment of muscle-invasive bladder cancer recurrences.

  Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica 20020601

• Central nervous system prophylaxis with high-dose methotrexate does not give rise to significant electroencephalographic changes in children with acute lymphoblastic leukemia.

  Journal of child neurology 20020601

• [2 years data of controlled trials with leflunomide vs. methotrexate and leflunomide vs. sulfasalazine].

  Zeitschrift fur Rheumatologie 20020601

• A prospective study of P-IMVP-16/CBDCA: a novel salvage chemotherapy for patients with aggressive non-Hodgkin's lymphoma who had previously received CHOP therapy as first-line chemotherapy.

  European journal of haematology 20020601

• Clinical characteristics of gestational trophoblastic disease at a single institute.

  The Tohoku journal of experimental medicine 20020601

• Methotrexate-associated liver toxicity in a patient with breast cancer: case report and literature review.

  The Netherlands journal of medicine 20020601

• [Retrospective study of adverse events in patients with rheumatoid arthritis treated with second-line drugs].

  Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi 20020601

• Alternating dose-dense chemotherapy in patients with high volume disseminated non-seminomatous germ cell tumours.

  British journal of cancer 20020520

• Self-aggregates of poly(2-hydroxyethyl aspartamide) copolymers loaded with methotrexate by physical and chemical entrapments.

  Journal of controlled release : official journal of the Controlled Release Society 20020517

• Intensified and shortened cyclical chemotherapy for adult acute lymphoblastic leukemia.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020515

• Interaction between methotrexate and ciprofloxacin.

  Journal of pediatric hematology/oncology 20020501

• Comparison of abortions induced by methotrexate or mifepristone followed by misoprostol.

  Obstetrics and gynecology 20020501

• CNS late-effects after ALL therapy in childhood. Part III: neuropsychological performance in long-term survivors of childhood ALL: impairments of concentration, attention, and memory.

  Medical and pediatric oncology 20020501

• Quantitative MRI assessment of leukoencephalopathy.

  Magnetic resonance in medicine 20020501

• Induction of apoptosis and modulation of activation and effector function in T cells by immunosuppressive drugs.

  Clinical and experimental immunology 20020501

• MR perfusion, diffusion and BOLD imaging of methotrexate-exposed swine brain.

  Journal of magnetic resonance imaging : JMRI 20020501

• HER-2 amplification and topoisomerase IIalpha gene aberrations as predictive markers in node-positive breast cancer patients randomly treated either with an anthracycline-based therapy or with cyclophosphamide, methotrexate, and 5-fluorouracil.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20020501

• A GAL4-based yeast three-hybrid system for the identification of small molecule-target protein interactions.

  Biochemical pharmacology 20020501

• Role of the C-terminus and the long cytoplasmic loop in reduced folate carrier expression and function.

  Biochemical pharmacology 20020501

• Population pharmacokinetics of adjuvant cyclophosphamide, methotrexate and 5-fluorouracil (CMF).

  European journal of cancer (Oxford, England : 1990) 20020501

• Influence of steroids and methotrexate on wound complications after elective rheumatoid hand and wrist surgery.

  The Journal of hand surgery 20020501

• Despite some expression of folate receptor alpha in human mesothelioma cells, internalization of methotrexate is predominantly carrier mediated.

  The Journal of thoracic and cardiovascular surgery 20020501

• Impact of leflunomide versus biologic agents on the costs of care for rheumatoid arthritis in a managed care population.

  The American journal of managed care 20020501

• Serum matrix metalloproteinase 3 levels during treatment with sulfasalazine or combination of methotrexate and sulfasalazine in patients with early rheumatoid arthritis.

  The Journal of rheumatology 20020501

• Multi-modality therapy leads to longer survival in primary central nervous system lymphoma patients.

  The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20020501

• [Chemotherapy and radiotherapy for urological cancer].

  Gan to kagaku ryoho. Cancer & chemotherapy 20020501

• [Incidence of emesis in outpatients on chemotherapy for breast cancer and the clinical efficacy of ondansetron hydrochloride tablets].

  Gan to kagaku ryoho. Cancer & chemotherapy 20020501

• In vitro effects of chemotherapeutic agents on human osteoblast-like cells.

  Calcified tissue international 20020501

• Methotrexate infusion and folinic acid as primary therapy for nonmetastatic and low-risk metastatic gestational trophoblastic tumors. 15 years of experience.

  The Journal of reproductive medicine 20020501

• Successful conservative treatment for advanced interstitial pregnancy. A case report.

  The Journal of reproductive medicine 20020501

• Advances in the medical management of rheumatoid arthritis.

  Hospital medicine (London, England : 1998) 20020501

• Urate-oxidase in the prevention and treatment of metabolic complications in patients with B-cell lymphoma and leukemia, treated in the Société Française d'Oncologie Pédiatrique LMB89 protocol.

  Annals of oncology : official journal of the European Society for Medical Oncology 20020501

• Use of disease-modifying antirheumatic drugs in patients with psoriatic arthritis.

  Joint, bone, spine : revue du rhumatisme 20020501

• Treatment of rheumatoid arthritis with methotrexate and hydroxychloroquine, methotrexate and sulfasalazine, or a combination of the three medications: results of a two-year, randomized, double-blind, placebo-controlled trial.

  Arthritis and rheumatism 20020501

• A multicenter, randomized, double-blind, placebo-controlled trial of adjuvant methotrexate treatment for giant cell arteritis.

  Arthritis and rheumatism 20020501

• Folic acid and folinic acid supplementation during low-dose methotrexate therapy for rheumatoid arthritis: comment on the article by van Ede et al.

  Arthritis and rheumatism 20020501

• Methotrexate twice weekly vs once weekly in rheumatoid arthritis: a pilot double-blind, controlled study.

  Rheumatology international 20020501

• [Breast carcinoma in accessory gland: a case report].

  Il Giornale di chirurgia 20020501

• [Primary renal non-Hodgkin lymphoma].

  La Tunisie medicale 20020501

• Synthesis of N-[4-[1-ethyl-2-(2,4-diaminofuro[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid as an antifolate.

  Journal of medicinal chemistry 20020425

• [Combination of mycophenolate mofetil with cyclosporine A and methotrexate for the prophylaxes of acute graft versus host disease in allogeneic peripheral stem cell transplantation].

  Zhonghua yi xue za zhi 20020425

• Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

  The Journal of biological chemistry 20020419

• [Skin nodules and ulcers of the limbs in a patient with rheumatoid arthritis].

  Deutsche medizinische Wochenschrift (1946) 20020405

• Anticardiolipin antibodies in rheumatoid patients treated with etanercept or conventional combination therapy: direct and indirect evidence for a possible association with infections.

  Annals of the rheumatic diseases 20020401

• A phase II trial of methotrexate-human serum albumin (MTX-HSA) in patients with metastatic renal cell carcinoma who progressed under immunotherapy.

  Cancer chemotherapy and pharmacology 20020401

• Analysis of kinetics using a hybrid maximum-entropy/nonlinear-least-squares method: application to protein folding.

  Biophysical journal 20020401

• Low-risk persistent gestational trophoblastic disease: outcome after initial treatment with low-dose methotrexate and folinic acid from 1992 to 2000.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020401

• Equivalence between ovarian suppression and chemotherapy in the adjuvant treatment of endocrine-responsive breast cancer.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020401

• Meeting highlights: International consensus panel on the treatment of primary breast cancer.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020401

• Hepatosplenic gammadelta T-cell lymphoma presenting with immune-mediated thrombocytopenia and hemolytic anemia (Evans' syndrome).

  American journal of hematology 20020401

• Choriocarcinoma and epithelial trophoblastic tumor: successful treatment of relapse with hysterectomy and high-dose chemotherapy with peripheral stem cell support: a case report.

  Gynecologic oncology 20020401

• Differing effects of methylenetetrahydrofolate reductase single nucleotide polymorphisms on methotrexate efficacy and toxicity in rheumatoid arthritis.

  Pharmacogenetics 20020401

• Polymorphisms in the methylenetetrahydrofolate reductase gene were associated with both the efficacy and the toxicity of methotrexate used for the treatment of rheumatoid arthritis, as evidenced by single locus and haplotype analyses.

  Pharmacogenetics 20020401

• Review article: monitoring for drug side-effects in inflammatory bowel disease.

  Alimentary pharmacology & therapeutics 20020401

• Chemotherapy-induced neurotoxicity: assessment and interventions for patients at risk.

  The American journal of nursing 20020401

• Delay to institution of therapy and induction of remission using single-drug or combination-disease-modifying antirheumatic drug therapy in early rheumatoid arthritis.

  Arthritis and rheumatism 20020401

• Less intense conditioning with fludarabine, cyclophosphamide, idarubicin and etoposide (FCIE) followed by allogeneic unselected peripheral blood stem cell transplantation in elderly patients with leukemia.

  Leukemia 20020401

• Long-term follow-up of short intensive multiagent chemotherapy without high-dose methotrexate ('Orange') in children with advanced non-lymphoblastic non-Hodgkin's lymphoma: a children's cancer group report.

  Leukemia 20020401

• Polymorphisms in methylenetetrahydrofolate reductase and methotrexate sensitivity in childhood acute lymphoblastic leukemia.

  Leukemia 20020401

• Drug survival, efficacy and toxicity of monotherapy with a fully human anti-tumour necrosis factor-alpha antibody compared with methotrexate in long-standing rheumatoid arthritis.

  Rheumatology (Oxford, England) 20020401

• Urticarial vasculitis: a paraneoplastic presentation of B-cell non-Hodgkin's lymphoma.

  Rheumatology (Oxford, England) 20020401

• [A case of gastric cancer with paraaortic lymph node metastasis responding to preoperative chemotherapy and surviving 4 years and 4 months after total gastrectomy].

  Gan to kagaku ryoho. Cancer & chemotherapy 20020401

• [A case of complete response (CR) persisting for 2 years and 10 months from UFT-E in a patient with liver metastasis of gastric cancer].

  Gan to kagaku ryoho. Cancer & chemotherapy 20020401

• Burkitt's lymphoma: single-centre experience with modified BFM protocol.

  Clinical and laboratory haematology 20020401

• Results of an international questionnaire on immunosuppressive treatment of multiple sclerosis.

  Multiple sclerosis (Houndmills, Basingstoke, England) 20020401

• Methotrexate leukoencephalopathy presenting as Klüver-Bucy syndrome and uncinate seizures.

  Pediatric neurology 20020401

• High dose ifosfamide in combination with high dose methotrexate, adriamycin and cisplatin in the neoadjuvant treatment of extremity osteosarcoma: preliminary results of an Italian Sarcoma Group/Scandinavian Sarcoma Group pilot study.

  Journal of chemotherapy (Florence, Italy) 20020401

• Folate status and the safety profile of antifolates.

  Seminars in oncology 20020401

• Multiple anomalies in a fetus exposed to low-dose methotrexate in the first trimester.

  Obstetrics and gynecology 20020401

• [Drug therapy and malpractice exemplified by combination leflunomide and methotrexate therapy].

  Zeitschrift fur Rheumatologie 20020401

• [Leflunomide + methotrexate combination therapy from the physician's viewpoint].

  Zeitschrift fur Rheumatologie 20020401

• Treatment of gestational trophoblastic tumors.

  Current treatment options in oncology 20020401

• [Prophylaxis of acute graft-versus-host disease after allogeneic bone marrow transplantation by mycophenolate mofetil in a murine model].

  Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20020401

• Ribosome display for selection of active dihydrofolate reductase mutants using immobilized methotrexate on agarose beads.

  FEBS letters 20020306

• Efficacy of carboplatin with an MEP (mitoxantrone, etoposide and prednisone) regimen for relapsed and CHOP-resistant diffuse large B-cell lymphomas.

  Leukemia research 20020301

• The MRP4/ABCC4 gene encodes a novel apical organic anion transporter in human kidney proximal tubules: putative efflux pump for urinary cAMP and cGMP.

  Journal of the American Society of Nephrology : JASN 20020301

• AIDS-related systemic non-Hodgkin's lymphoma at a large community program.

  AIDS research and human retroviruses 20020301

• Methotrexate exacerbates tumor progression in a murine model of chronic myeloid leukemia.

  The Journal of pharmacology and experimental therapeutics 20020301

• Phase III trial of fluorouracil, interferon alpha-2b, and cisplatin versus methotrexate, vinblastine, doxorubicin, and cisplatin in metastatic or unresectable urothelial cancer.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020301

• Phase I pharmacokinetic and sequence finding study of the combination of docetaxel and methotrexate in patients with solid tumours.

  European journal of cancer (Oxford, England : 1990) 20020301

• C-erbB-2 expression does not predict response to docetaxel or sequential methotrexate and 5-fluorouracil in advanced breast cancer.

  European journal of cancer (Oxford, England : 1990) 20020301

• Nephrotoxicity due to intermediate-dose methotrexate without rescue in an obese adolescent with acute lymphoblastic leukemia.

  Pediatric hematology and oncology 20020301

• Comparison of weakness progression in inclusion body myositis during treatment with methotrexate or placebo.

  Annals of neurology 20020301

• The predictive value of bcl-2, bax, bcl-xL, bag-1, fas, and fasL for chemotherapy response in advanced breast cancer.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20020301

• Methotrexate selection of long-term culture initiating cells following transduction of CD34(+) cells with a retrovirus containing a mutated human dihydrofolate reductase gene.

  Cancer gene therapy 20020301

• Methotrexate-induced apoptosis in hepatocytes after partial hepatectomy.

  European journal of pharmacology 20020301

• Pharmacological characterization of the ATP-dependent low K(m) guanosine 3',5'-cyclic monophosphate (cGMP) transporter in human erythrocytes.

  Biochemical pharmacology 20020301

• [A case of subacute transient cerebral dysfunction in a osteosarcoma patient following high-dose methotrexate].

  Gan to kagaku ryoho. Cancer & chemotherapy 20020301

• Anti-tumour necrosis factor treatment with infliximab in a case of giant cell arteritis resistant to steroid and immunosuppressive drugs.

  Rheumatology (Oxford, England) 20020301

• Successful autologous peripheral blood stem cell transplantation in transformed follicular lymphoma previously treated with radioimmunotherapy (iodine (131)I tositumomab).

  Bone marrow transplantation 20020301

• CT and MRI appearances of methotrexate leucoencephalopathy.

  Australasian radiology 20020301

• Expression, modulation and signalling of IL-17 receptor in fibroblast-like synoviocytes of patients with rheumatoid arthritis.

  Clinical and experimental immunology 20020301

• Invasive ductal carcinoma associated with tubular adenoma of the breast.

  Pathology international 20020301

• Rheumatoid arthritis: limiting the damage.

  Nursing times 20020301

• [Chronic polyradiculoneuritis disclosing sarcoidosis].

  Revue neurologique 20020301

• [Bone destruction and bone loss in rheumatoid arthritis--mechanism, prevention and treatment].

  Nihon rinsho. Japanese journal of clinical medicine 20020301

• Synthesis of a novel phosphatidylcholine conjugated to docosahexaenoic acid and methotrexate that inhibits cell proliferation.

  Anti-cancer drugs 20020301

• [Dual gene amplification and selection system with dihydrofolate reductase and glutamine synthetase genes effectively increase the foreign gene expression].

  Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology 20020301

• The feasibility of classical cyclophosphamide, methotrexate, 5-fluorouracil (CMF) for pre- and post-menopausal node-positive breast cancer patients in a Belgian multicentric trial: a study of consistency in relative dose intensity (RDI) and cumulative doses across institutions.

  Annals of oncology : official journal of the European Society for Medical Oncology 20020301

• Systemic immunosuppression fails to suppress cardiac cytokine induction in pressure overload hypertrophy in rats.

  Immunobiology 20020301

• A case of twin pregnancy with complete hydatidiform mole and coexisting fetus following IVF-ET.

  Journal of assisted reproduction and genetics 20020301

• Radiation myelitis in a 5-year-old girl.

  Journal of child neurology 20020301

• Establishment and characterization of new murine breast cancer cell lines.

  Archiv der Pharmazie 20020301

• Unrecognized cervical pregnancy treated by suction curettage and cervicovaginal tamponade.

  Zentralblatt fur Gynakologie 20020301

• Multidrug resistance (MDR-1) expression in AIDS-related lymphomas.

  Leukemia research 20020201

• Acute T-lymphoblastic leukemia relapsed with the character of myeloid/natural killer cell precursor phenotype: a case report.

  Leukemia research 20020201

• Renal outcome in Wegener's granulomatosis.

  Current rheumatology reports 20020201

• Chemotherapy for trophoblastic disease: current standards.

  Current opinion in obstetrics & gynecology 20020201

• Prognostic value of thymidine phosphorylase expression in breast carcinoma.

  International journal of cancer 20020201

• Cost-effectiveness comparison of therapy for psoriasis with a methotrexate-based regimen versus a rotation regimen of modified cyclosporine and methotrexate.

  Journal of the American Academy of Dermatology 20020201

• Methotrexate-induced systemic vasculitis.

  Medical and pediatric oncology 20020201

• Chemotherapy versus hormonal adjuvant treatment in premenopausal patients with breast cancer.

  European journal of cancer (Oxford, England : 1990) 20020201

• Role of radiotherapy in the treatment of supratentorial primitive neuroectodermal tumors in childhood: results of the prospective German brain tumor trials HIT 88/89 and 91.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020201

• High-level expression of human thyroid-stimulating hormone in Chinese hamster ovary cells by co-transfection of dicistronic expression vectors followed by a dual-marker amplification strategy.

  Biotechnology and applied biochemistry 20020201

• Effect of methotrexate polyglutamates on thioguanine nucleotide concentrations during continuation therapy of acute lymphoblastic leukemia with mercaptopurine.

  Leukemia 20020201

• Point mutations of the BCL-6 gene: clinical and prognostic correlation in B-diffuse large cell lymphoma.

  Leukemia 20020201

• COBRA combination therapy in patients with early rheumatoid arthritis: long-term structural benefits of a brief intervention.

  Arthritis and rheumatism 20020201

• Comparative assessment of leflunomide and methotrexate for the treatment of rheumatoid arthritis, by dynamic enhanced magnetic resonance imaging.

  Arthritis and rheumatism 20020201

• Clinical experience of capecitabine in metastatic breast cancer.

  European journal of cancer (Oxford, England : 1990) 20020201

• CsA-based post-graft immunosuppression: the main factor for improving outcome of allografted patients with acquired aplastic anemia. A retrospective survey by the Spanish Group of Hematopoietic Transplantation.

  Bone marrow transplantation 20020201

• [Clinical usefulness of ondansetron hydrochloride for nausea and vomiting during repeated courses of chemotherapy for malignant lymphoma--impact of prognosis announcement on anti-emetic effect and evaluation of patient perception of chemotherapy-associated adverse events].

  Gan to kagaku ryoho. Cancer & chemotherapy 20020201

• Significant impairment of high-dose methotrexate clearance following vancomycin administration in the absence of overt renal impairment.

  Annals of oncology : official journal of the European Society for Medical Oncology 20020201

• Radiographic outcome after three years of patients with early erosive rheumatoid arthritis treated with intramuscular methotrexate or parenteral gold. Extension of a one-year double-blind study in 174 patients.

  Rheumatology (Oxford, England) 20020201

• Methotrexate-induced nephrogenic diabetes insipidus: first case report.

  Rheumatology (Oxford, England) 20020201

• Current and future perspectives in advanced bladder cancer: is there a new standard?

  Seminars in oncology 20020201

• Gemcitabine doublets in advanced urothelial cancer.

  Seminars in oncology 20020201

• Novel gemcitabine-containing triplets in the management of urothelial cancer.

  Seminars in oncology 20020201

• Weight gain during adjuvant and neoadjuvant chemotherapy for breast cancer: an audit of 100 women receiving FEC or CMF chemotherapy.

  Clinical oncology (Royal College of Radiologists (Great Britain)) 20020201

• Cervical pregnancy: two case reports.

  Connecticut medicine 20020201

• [A case of rheumatoid arthritis complicated with a pneumonitis during concomitant treatment with methotrexate and bucillamine].

  Ryumachi. [Rheumatism] 20020201

• [A survey of the doses of methotrexate and salazosulfapyridine in Japanese patients with rheumatoid arthritis].

  Ryumachi. [Rheumatism] 20020201

• Experience with etanercept in an academic medical center: are infection rates increased?

  Arthritis and rheumatism 20020201

• Step-down approach using either cyclosporin A or methotrexate as maintenance therapy in early rheumatoid arthritis.

  Arthritis and rheumatism 20020201

• Therapeutic approaches to secondary progressive multiple sclerosis.

  Multiple sclerosis (Houndmills, Basingstoke, England) 20020201

• [Pharmacogenomics of the immunosuppressive agents].

  Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology 20020201

• No major cognitive impairment in young children with acute lymphoblastic leukemia using chemotherapy only: a prospective longitudinal study.

  Journal of pediatric hematology/oncology 20020201

• Pediatric acute lymphoblastic leukemia: redefining outcomes.

  Journal of pediatric hematology/oncology 20020201

• [The effect of low dose methotrexate treatment on bone mineral density in patients with rheumatoid arthritis].

  Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20020201

• Expression of P53 and bcl-2 proteins in T-cell lymphoblastic lymphoma: prognostic implications.

  Leukemia & lymphoma 20020201

• DNA ploidy and S-phase fraction as predictive factors of response and outcome following neoadjuvant methotrexate, vinblastine, epirubicin and cisplatin (M-VEC) chemotherapy for invasive bladder cancer.

  Scandinavian journal of urology and nephrology 20020201

• Leptomeningeal carcinomatosis after major remission to taxane-based front-line therapy in patients with advanced breast cancer.

  Journal of neuro-oncology 20020201

• [Adult Still's disease: study of a series of 11 cases].

  Journal des maladies vasculaires 20020201

• Polyglutamation of a novel antifolate, MX-68, is not necessary for its anti-arthritic effect.

  European journal of pharmacology 20020125

• Weekly pulse therapy of methotrexate improves survival compared with its daily administration in MRL/lpr mice.

  European journal of pharmacology 20020125

• Granulocyte colony-stimulating factor in induction treatment of children with non-Hodgkin's lymphoma: a randomized study of the French Society of Pediatric Oncology.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020115

• Rapidly alternating COPP/ABV/IMEP is not superior to conventional alternating COPP/ABVD in combination with extended-field radiotherapy in intermediate-stage Hodgkin's lymphoma: final results of the German Hodgkin's Lymphoma Study Group Trial HD5.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020115

• Multiple mechanisms of resistance to methotrexate and novel antifolates in human CCRF-CEM leukemia cells and their implications for folate homeostasis.

  Biochemical pharmacology 20020115

• Biotinylated methotrexate loaded erythrocytes for enhanced liver uptake. 'A study on the rat'.

  International journal of pharmaceutics 20020114

• Highly divergent dihydrofolate reductases conserve complex folding mechanisms.

  Journal of molecular biology 20020111

• [Safety aspects of folic acid for the general population].

  Praxis 20020109

• High-dose cyclophosphamide followed by autologous peripheral blood progenitor cell transplantation improves the salvage treatment for persistent or sensitive relapsed malignant lymphoma.

  Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20020101

• Prognostic implications of BCL6 rearrangement in uniformly treated patients with diffuse large B-cell lymphoma--a Nordic Lymphoma Group study.

  International journal of oncology 20020101

• Ventral polyradiculopathy with pediatric acute lymphocytic leukemia.

  Muscle & nerve 20020101

• Reduced-intensity conditioning followed by allografting of hematopoietic cells can produce clinical and molecular remissions in patients with poor-risk hematologic malignancies.

  Blood 20020101

• The effect of treatment and its related side effects in patients with severe ocular cicatricial pemphigoid.

  Ophthalmology 20020101

• Importance of radiotherapy in the outcome of patients with primary CNS lymphoma: an analysis of the CHOD/BVAM regimen followed by two different radiotherapy treatments.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020101

• Current treatment of juvenile rheumatoid arthritis.

  Pediatrics 20020101

• Technical factors associated with radiation pneumonitis after local +/- regional radiation therapy for breast cancer.

  International journal of radiation oncology, biology, physics 20020101

• A case of weak muscles.

  Annals of the rheumatic diseases 20020101

• Giant cell arteritis.

  Current opinion in rheumatology 20020101

• Effective treatment of early rheumatoid arthritis with a combination of methotrexate, prednisolone and cyclosporin.

  Rheumatology (Oxford, England) 20020101

• Methotrexate-related nonnecrotizing multifocal axonopathy detected by beta-amyloid precursor protein immunohistochemistry.

  Archives of pathology & laboratory medicine 20020101

• [A patient with advanced gastric cancer surviving for more than 5 years after neoadjuvant chemotherapy and curative resection].

  Gan to kagaku ryoho. Cancer & chemotherapy 20020101

• Association of baseline levels of urinary glucosyl-galactosyl-pyridinoline and type II collagen C-telopeptide with progression of joint destruction in patients with early rheumatoid arthritis.

  Arthritis and rheumatism 20020101

• Economic comparison of leflunomide and methotrexate in patients with rheumatoid arthritis: an evaluation based on a 1-year randomised controlled trial.

  PharmacoEconomics 20020101

• Fatal hemorrhage after radiochemotherapy for leptomeningeal dissemination of glioma: report of two cases.

  Surgical neurology 20020101

• Treatment of children and adolescents with localized parameningeal sarcoma: experience of the Intergroup Rhabdomyosarcoma Study Group protocols IRS-II through -IV, 1978-1997.

  Medical and pediatric oncology 20020101

• Transport activity of human MRP3 expressed in Sf9 cells: comparative studies with rat MRP3.

  Pharmaceutical research 20020101

• Bronchiolitis obliterans in a case of juvenile rheumatoid arthritis presented with pneumomediastinum.

  Respiration; international review of thoracic diseases 20020101

• [Infliximab in aggressive and refractory rheumatoid arthritis. A pilot study].

  Recenti progressi in medicina 20020101

• Second-line drugs used in recent-onset rheumatoid arthritis in Brittany (France).

  Joint, bone, spine : revue du rhumatisme 20020101

• Progesterone receptor status of breast cancer metastases.

  Journal of cancer research and clinical oncology 20020101

• Successful treatment of transitional cell carcinoma of the urethra with chemotherapy.

  Cancer investigation 20020101

• Leukemic leptomeningeal involvement in stage 0 and stage 1 chronic lymphocytic leukemia.

  Leukemia & lymphoma 20020101

• [An autopsy case of pulmonary and central nervous system metastatic osteosarcoma treated with thirty-six courses of chemotherapy over four years].

  Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20020101

• Effect of a 3-hour interval between methotrexate and 5-fluorouracil in the treatment of metastatic colorectal cancer.

  Japanese journal of clinical oncology 20020101

• [Mycophenolate mofetil in refractory Crohn's disease after failure of treatments by azathioprine or methotrexate].

  Gastroenterologie clinique et biologique 20020101

• Rheumatoid arthritis.

  Journal of the Medical Association of Georgia 20020101

• Cutaneous pleomorphic T-cell lymphoma coexisting with myelodysplastic syndrome transforming into acute myeloid leukemia: successful treatment with a fludarabine-containing regimen.

  European journal of haematology 20020101

• The expanding role of epirubicin in the treatment of breast cancer.

  Cancer control : journal of the Moffitt Cancer Center 20020101

• [Prognostic factors in lymph node negative breast cancer].

  Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] 20020101

• [Comparison of epirubicin and cyclophosphamide in 2-dose levels and classical CMF protocol in node-positive breast cancer. An adjuvant Phase III trial].

  Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] 20020101

• Neurotoxicity with leukoencephalopathy after a single intravenous high dose of methotrexate in a patient with lymphoma.

  Acta haematologica 20020101

• Schedule-selective biochemical modulation of 5-fluorouracil in advanced colorectal cancer--a phase II study.

  BMC cancer 20020101

• Intermediate-dose methotrexate and intravenous 6-mercaptopurine chemotherapy for children with acute lymphoblastic leukemia who did not respond to initial induction therapy.

  Journal of pediatric hematology/oncology 20020101

• Bullous acral erythema secondary to high-dose methotrexate.

  Journal of pediatric hematology/oncology 20020101

• Assessment of drug activity and proliferation ex vivo for prediction of outcome in aggressive non-Hodgkin's lymphomas.

  Acta oncologica (Stockholm, Sweden) 20020101

• Physical performance, toxicity, and quality of life as assessed by the physician and the patient.

  Acta oncologica (Stockholm, Sweden) 20020101

• Sequence- and time-dependent antagonism between raloxifene and methotrexate in human breast cancer cells.

  Anticancer research 20020101

• The impact of induction duration and the number of high-dose cycles on the long-term survival of women with metastatic breast cancer treated with high-dose chemotherapy with stem cell rescue: an analysis of sequential phase I/II trials from the Dana-Farber/Beth Israel STAMP program.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20020101

• Dihydropyrimidine dehydrogenase enzyme deficiency: clinical and genetic assessment of prevalence in Turkish cancer patients.

  Cancer investigation 20020101

• Central nervous system prophylaxis in haematological malignancies.

  Internal medicine journal 20020101

• Genotoxicity assessment using micronuclei assay in rheumatoid arthritis patients.

  Clinical and experimental rheumatology 20020101

• Combining cyclosporine with prevailing antirheumatic drug therapy in the treatment of juvenile idiopathic arthritis.

  Clinical and experimental rheumatology 20020101

• Clinical relevance of soluble c-erbB-2 for patients with metastatic breast cancer predicting the response to second-line hormone or chemotherapy.

  Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20020101

• Dextromethorphan is effective in the treatment of subacute methotrexate neurotoxicity.

  Pediatric hematology and oncology 20020101

• Treatment of giant-cell arteritis: where we have been and why we must move on.

  Cleveland Clinic journal of medicine 20020101

• [Changes in clinical and laboratory findings on oxidation metabolism in lymphocyte membranes of rheumatoid arthritis patients on synchronous programmed intensive therapy].

  Klinicheskaia meditsina 20020101

• [Synchronous programmed intensive therapy of patients with severe rheumatoid arthritis].

  Terapevticheskii arkhiv 20020101

• Long-term survival after regional chemotherapy for liver metastases from breast cancer. A case report.

  Tumori 20020101

• Altered subcellular localization of p53 in estrogen-dependent and estrogen-independent breast cancer cells.

  Cancer investigation 20020101

• Is there life after methotrexate?

  Cancer investigation 20020101

• [Peripheral blood hematopoietic cell transplant using immunosuppressive chemotherapy without bone marrow destruction: 'minitransplant'].

  Gaceta medica de Mexico 20020101

• Combination therapy with cyclosporine and methotrexate in patients with early rheumatoid arthritis soon inhibits TNFalpha production without decreasing TNFalpha mRNA levels. An in vivo and in vitro study.

  Clinical and experimental rheumatology 20020101

• Molecular action of methotrexate in inflammatory diseases.

  Arthritis research 20020101

• Study of chromosome damage in patients with breast cancer treated by two antineoplastic treatments.

  Teratogenesis, carcinogenesis, and mutagenesis 20020101

• Polyethylene glycol conjugates of methotrexate varying in their molecular weight from MW 750 to MW 40000: synthesis, characterization, and structure-activity relationships in vitro and in vivo.

  Bioconjugate chemistry 20020101

• Local methotrexate and dexamethasone phosphate for the treatment of recurrent primary intraocular lymphoma.

  Ophthalmic surgery and lasers 20020101

• [Unrelated donor stem cell transplantation in children: low toxicity using a GvHD-prophylaxis regimen with CSA, MTX, metronidazole,iv-immunoglobulin and ATG].

  Klinische Padiatrie 20020101

• Cyclophosphamide, methotrexate and fluorouracil (CMF) versus hormonal ablation with leuprorelin acetate as adjuvant treatment of node-positive, premenopausal breast cancer patients: preliminary results of the TABLE-study (Takeda Adjuvant Breast cancer study with Leuprorelin Acetate).

  Anticancer research 20020101

• 3-year results of docetaxel-based sequential and combination regimens in the adjuvant therapy of node-positive breast cancer: a pilot study.

  Anticancer research 20020101

• Combination therapy with methotrexate and cyclosporine A in juvenile idiopathic arthritis.

  Clinical and experimental rheumatology 20020101

• Neoadjuvant chemotherapy with sequential methotrexate and 5-fluorouracil scheduling, epirubicin and cisplatin for locally advanced bladder cancer.

  Oncology 20020101

• Isolated leptomeningeal carcinomatosis (carcinomatous meningitis) after taxane-induced major remission in patients with advanced breast cancer.

  Oncology 20020101

• Immune reconstitution during intensive chemotherapy in patients with human immunodeficiency virus related non-Hodgkin lymphoma.

  The hematology journal : the official journal of the European Haematology Association 20020101

• [Medical methods for pregnancy termination. A review of literature and its potential role in Mexico and Latin America].

  Gaceta medica de Mexico 20020101

• [Arterial chemoembolization in the combined treatment of malignant tumors of the tongue and maxilla: preliminary results].

  Vestnik rentgenologii i radiologii 20020101

• A simple technique for high-throughput screening of drugs that modulate normal and psoriasis-like differentiation in cultured human keratinocytes.

  Skin pharmacology and applied skin physiology 20020101

• [Infections of the musculoskeletal system with chronic polyarthritis during a combination therapy with Methotrexate and Leflunomide].

  Zeitschrift fur Orthopadie und ihre Grenzgebiete 20020101

• Mycophenolic acid and methotrexate inhibit lymphocyte cytokine production via different mechanisms.

  European cytokine network 20020101

• Emperipolesis in a common breast malignancy. A case report.

  Acta cytologica 20020101

• Comparative tolerability of systemic treatments for plaque-type psoriasis.

  Drug safety 20020101

• Second-line chemotherapy with a hybrid-alternating regimen of bolus 5FU modulated by methotrexate and infusional 5FU modulated by folinic acid in patients with metastatic colorectal cancer pretreated with 5FU. A phase 2 study.

  Oncology 20020101

• Inhalation delivery of anticancer agents via HFA-based metered dose inhaler using methotrexate as a model drug.

  Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine 20020101

• Efficacy of a primary chemotherapy regimen combining vinorelbine, epirubicin, and methotrexate (VEM) as neoadjuvant treatment in 89 patients with operable breast cancer.

  The oncologist 20020101

• Use of transcutaneous nerve stimulation wristband to treat methotrexate-induced nausea.

  Journal of cutaneous medicine and surgery 20020101

• Severe folate restriction results in depletion of and alteration in the composition of the intracellular folate pool, moderate sensitization to methotrexate and trimetrexate, upregulation of endogenous DHFR activity, and overexpression of metallothionein II and folate receptor alpha that, upon folate repletion, confer drug resistance to CHL cells.

  Journal of experimental therapeutics & oncology 20020101

• Options for early therapeutic abortion: a comparative review.

  Drugs 20020101

• Fibroblastic rheumatism: case report and review of the literature.

  Pediatric dermatology 20020101

• Neoadjuvant chemotherapy with cisplatin and methotrexate in patients with muscle-invasive bladder tumours.

  Acta oncologica (Stockholm, Sweden) 20020101

• Monitoring and assessing the safety of disease-modifying antirheumatic drugs: a West Midlands experience.

  Drug safety 20020101

• Effects of disease modifying agents and dietary intervention on insulin resistance and dyslipidemia in inflammatory arthritis: a pilot study.

  Arthritis research 20020101

• [Results of the treatment of childhood acute lymphoblastic leukemia according to the Berlin-Moscow-91 protocol in 1991-2000].

  Voprosy onkologii 20020101

• [Treatment of acute lymphoblastic leukemia in children according to the ALL-BFM-90m protocol in the Russian Federation and the Republic of Belarus].

  Voprosy onkologii 20020101

• Treatment of ankylosing spondylitis with disease modifying antirheumatic drugs.

  Clinical and experimental rheumatology 20020101

• Methotrexate in psoriatic arthritis.

  Clinical and experimental rheumatology 20020101

• [Diagnosis and treatment of rheumatoid arthritis].

  Medicina (Kaunas, Lithuania) 20020101

• Experimental modulation of cell-cell adhesion, invasiveness and differentiation in trophoblast cells.

  Cells, tissues, organs 20020101

• Genomic imbalances in drug-resistant T-cell acute lymphoblastic CEM leukemia cell lines.

  Blood cells, molecules & diseases 20020101

• Light and electron microscopic analysis of liver biopsy samples from rheumatoid arthritis patients receiving long-term methotrexate therapy.

  Scandinavian journal of rheumatology 20020101

• Chemotherapy-induced amenorrhea and fertility in women undergoing adjuvant treatment for breast cancer.

  Cancer control : journal of the Moffitt Cancer Center 20020101

• Transport of methotrexate into LNCaP human prostate cancer cells.

  BioFactors (Oxford, England) 20020101

• Ligand binding characteristics of two molecular forms, one equipped with a hydrophobic glycosyl phosphatidylinositol tail, of the folate binding protein purified from human milk.

  Bioscience reports 20020101

• The combined effects of antibacterial peptide cecropin A and anti-cancer agents on leukemia cells.

  Anticancer research 20020101

• Intrathecal chemotherapy in carcinomatous meningitis from breast cancer.

  Anticancer research 20020101

• A phase II study of weekly methotrexate, cisplatin, and 24-hour infusion of high-dose 5-fluorouracil and leucovorin (MP-HDFL) in patients with metastatic and recurrent esophageal cancer-improving toxicity profile by infusional schedule and double biochemical modulation of 5-fluorouracil.

  Anticancer research 20020101

• Thymidylate synthase and p53 expression in primary tumor do not predict chemotherapy outcome in metastatic colorectal carcinoma.

  Anticancer research 20020101

• [Evolution of adjuvant chemotherapy of breast cancer from Bonadonna to the taxanes].

  Magyar onkologia 20020101

• [Ocular relapse of acute lymphoblastic leukemia].

  Bulletin de la Societe belge d'ophtalmologie 20020101

• IgA pemphigus: the first two Scandinavian cases.

  Acta dermato-venereologica 20020101

• [Conservative treatment of ectopic pregnancy with methotrexate].

  Akusherstvo i ginekologiia 20020101

• [Treatment of patients with invasive bladder cancer].

  Urologiia (Moscow, Russia : 1999) 20020101

• Plasma from rheumatoid patients taking low dose methotrexate enhances platelet aggregation.

  Research communications in molecular pathology and pharmacology 20020101

• The use of G-CSF during first line chemotherapy adversely affects the yield of PBSC mobilization in non-Hodgkin's lymphoma patients.

  Advances in clinical pathology : the official journal of Adriatic Society of Pathology 20020101

• Nonablative allogeneic hematopoietic transplantation as adoptive immunotherapy for indolent lymphoma: low incidence of toxicity, acute graft-versus-host disease, and treatment-related mortality.

  Blood 20011215

• Chemotherapy with an every-2-week regimen of gemcitabine and paclitaxel in patients with transitional cell carcinoma who have received prior cisplatin-based therapy.

  Cancer 20011215

• [New developments in chemotherapy for metastasized bladder cancer].

  Nederlands tijdschrift voor geneeskunde 20011215

• Progress in the treatment of rheumatoid arthritis.

  JAMA 20011212

• Methotrexate in giant-cell arteritis.

  Annals of internal medicine 20011204

• Combination chemotherapy of the taxanes and antimetabolites: its use and limitations.

  European journal of cancer (Oxford, England : 1990) 20011201

• Locally advanced primary breast cancer: medium-term results of a randomised trial of multimodal therapy versus initial hormone therapy.

  European journal of cancer (Oxford, England : 1990) 20011201

• Long-term impact of chemotherapy-induced ovarian failure on bone mineral density (BMD) in premenopausal breast cancer patients. The effect of adjuvant clodronate treatment.

  European journal of cancer (Oxford, England : 1990) 20011201

• Infundibulohypophysitis in a man presenting with diabetes insipidus and cavernous sinus involvement.

  Journal of neurology, neurosurgery, and psychiatry 20011201

• Subcutaneous panniculitic T-cell lymphoma in childhood: successful response to chemotherapy.

  Medical and pediatric oncology 20011201

• Management of a 16-year-old boy with adenocarcinoma at the esophageal gastric junction.

  Medical and pediatric oncology 20011201

• CD34(+) cell subsets and long-term culture colony-forming cells evaluated on both autologous and normal bone marrow stroma predict long-term hematopoietic engraftment in patients undergoing autologous peripheral blood stem cell transplantation.

  Experimental hematology 20011201

• [Effective treatment with Lamivudine of patients with reactivation of hepatitis B following chemotherapy administration].

  Harefuah 20011201

• P16INK4a protein expression is associated with poor survival of the breast cancer patients after CMF chemotherapy.

  Breast cancer research and treatment 20011201

• Intracellular glutathione deficiency is associated with enhanced nuclear factor-kappaB activation in older non-insulin dependent diabetic patients.

  Free radical research 20011201

• Therapy for Australian cats with lymphosarcoma.

  Australian veterinary journal 20011201

• Role of non-alcoholic steatohepatitis in methotrexate-induced liver injury.

  Journal of gastroenterology and hepatology 20011201

• Lymphoblasts already in the DNA synthesis phase of the cell cycle can be reversibly arrested at the R/G transition.

  Chromosoma 20011201

• Randomized, double-blind, crossover, placebo-controlled trial of intravenous ondansetron for the prevention of intrathecal chemotherapy-induced vomiting in children.

  Journal of pediatric hematology/oncology 20011201

• Low relapse rate in children with acute lymphoblastic leukemia after risk-directed therapy.

  Journal of pediatric hematology/oncology 20011201

• Successful treatment of refractory Langerhans cell histiocytosis with unrelated cord blood transplantation.

  Journal of pediatric hematology/oncology 20011201

• Unrelated cord blood transplantation for an infant with chemotherapy-resistant progressive Langerhans cell histiocytosis.

  Journal of pediatric hematology/oncology 20011201

• Continuing therapy for childhood acute lymphoblastic leukaemia: clinical and cellular pharmacology of methotrexate, 6-mercaptopurine and 6-thioguanine.

  Cancer treatment reviews 20011201

• [Central nervous system involvement in Behçet's disease].

  Rinsho shinkeigaku = Clinical neurology 20011201

• [The binding characteristics of insulin-MTX to insulin receptor].

  Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao 20011201

• Separation methods for methotrexate, its structural analogues and metabolites.

  Journal of chromatography. B, Biomedical sciences and applications 20011125

• What is the ideal duration of adjuvant therapy for primary breast cancer: are four cycles of cyclophosphamide and doxorubicin enough?

  Current oncology reports 20011101

• Neoadjuvant chemotherapy for osteosarcoma of the extremity: long-term results of the Rizzoli's 4th protocol.

  European journal of cancer (Oxford, England : 1990) 20011101

• Expression of the reduced folate carrier SLC19A1 in IEC-6 cells results in two distinct transport activities.

  American journal of physiology. Cell physiology 20011101

• Treatment of psoriasis. Part 2. Systemic therapies.

  Journal of the American Academy of Dermatology 20011101

• The role of caspases in methotrexate-induced gastrointestinal toxicity.

  Surgery 20011101

• Influence of endocrine-related factors on response to perioperative chemotherapy for patients with node-negative breast cancer.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20011101

• Single nucleotide polymorphisms in the human reduced folate carrier: characterization of a high-frequency G/A variant at position 80 and transport properties of the His(27) and Arg(27) carriers.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20011101

• Bone turnover, joint damage and bone mineral density in early rheumatoid arthritis treated with combination therapy including high-dose prednisolone.

  Rheumatology (Oxford, England) 20011101

• The C677T mutation in the methylenetetrahydrofolate reductase gene: a genetic risk factor for methotrexate-related elevation of liver enzymes in rheumatoid arthritis patients.

  Arthritis and rheumatism 20011101

• Demonstration of response in rheumatoid arthritis patients who are nonresponders according to the American College of Rheumatology 20% criteria: the paradox of beneficial treatment effects in nonresponders in the ATTRACT trial. Anti-Tumor Necrosis Factor Trial in Rheumatoid Arthritis with Concomitant Therapy.

  Arthritis and rheumatism 20011101

• Localization of organic anion transporting polypeptide 4 (Oatp4) in rat liver and comparison of its substrate specificity with Oatp1, Oatp2 and Oatp3.

  Pflugers Archiv : European journal of physiology 20011101

• Carrier-mediated transport of folic acid in BeWo cell monolayers as a model of the human trophoblast.

  Placenta 20011101

• Treatment of acrodermatitis continua of Hallopeau with oral propylthiouracil and methotrexate.

  Clinical and experimental dermatology 20011101

• Management of fistulas in patients with Crohn's disease: antibiotic to antibody.

  Canadian journal of gastroenterology = Journal canadien de gastroenterologie 20011101

• [Neoadjuvant chemotherapy for invasive bladder cancer].

  Gan to kagaku ryoho. Cancer & chemotherapy 20011101

• Dermatomyositis.

  American family physician 20011101

• Adjuvant chemotherapy for osteosarcoma may not increase survival after neoadjuvant chemotherapy and surgical resection.

  Journal of surgical oncology 20011101

• Comparison of long-term outcome of children and adolescents with disseminated non-lymphoblastic non-Hodgkin lymphoma treated with COMP or daunomycin-COMP: A report from the Children's Cancer Group.

  Medical and pediatric oncology 20011101

• [Erythroderma after corticosteroid withdrawal in papulosquamous dermatosis in children. Diagnosis: pityriasis rubra pilaris, classic juvenile type].

  Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20011101

• Adult lymphoblastic lymphoma in Taiwan: an analysis of treatment results of 26 patients.

  Annals of hematology 20011101

• [Locally advanced or metastatic bladder carcinoma. Current aspects of therapy].

  Der Urologe. Ausg. A 20011101

• Chemoradiation for metastatic SCCA: role of comorbidity.

  The Laryngoscope 20011101

• Result of two randomized trials comparing nolatrexed (Thymitaq) versus methotrexate in patients with recurrent head and neck cancer.

  Annals of oncology : official journal of the European Society for Medical Oncology 20011101

• Comparative study of bulky stage IB and IA cervical cancer patients treated by radical hysterectomy with and without neoadjuvant chemotherapy: long-term follow-up.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20011101

• Medical management of cervical pregnancy--a report of two cases.

  Singapore medical journal 20011101

• [A clinical study of haploidentical transplantation using granulocyte colony-stimulating factor stimulating donor bone marrow].

  Zhonghua nei ke za zhi 20011101

• [Dermatomyositis and polymyositis: clinical aspects and treatment].

  Annales de medecine interne 20011101

• Methylation-dependent silencing of the reduced folate carrier gene in inherently methotrexate-resistant human breast cancer cells.

  The Journal of biological chemistry 20011026

• Clinical, immunologic, and pathologic correlates of bone marrow involvement in 291 patients with acquired immunodeficiency syndrome-related lymphoma.

  Blood 20011015

• Brief-duration high-intensity chemotherapy for patients with small noncleaved-cell lymphoma or FAB L3 acute lymphocytic leukemia: results of cancer and leukemia group B study 9251.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20011015

• Levels of phospholipid metabolites in breast cancer cells treated with antimitotic drugs: a 31P-magnetic resonance spectroscopy study.

  Cancer research 20011015

• Is there a place for leflunomide in the treatment of rheumatoid arthritis?

  Lancet (London, England) 20011013

• Mutation of Trp1254 in the multispecific organic anion transporter, multidrug resistance protein 2 (MRP2) (ABCC2), alters substrate specificity and results in loss of methotrexate transport activity.

  The Journal of biological chemistry 20011012

• [Meningeal carcinomatosis as the first manifestation of gastric adenocarcinoma].

  Casopis lekaru ceskych 20011011

• Overexpression of folate binding protein alpha is one of the mechanism explaining the adaptation of HT29 cells to high concentration of methotrexate.

  Cancer letters 20011010

• Hydrogels for combination delivery of antineoplastic agents.

  Biomaterials 20011001

• Multispecific substrate recognition of kidney-specific organic anion transporters OAT-K1 and OAT-K2.

  The Journal of pharmacology and experimental therapeutics 20011001

• Recent advances in the treatment of the seronegative spondyloarthropathies.

  Current rheumatology reports 20011001

• Transport of methotrexate into PC-3 human prostate cancer cells.

  Archives of biochemistry and biophysics 20011001

• Clinical relevance of consolidation radiotherapy and other main therapeutic issues in primary central nervous system lymphomas treated with upfront high-dose methotrexate.

  International journal of radiation oncology, biology, physics 20011001

• A role for methotrexate in the management of non-infectious orbital inflammatory disease.

  The British journal of ophthalmology 20011001

• Lack of pharmacokinetic interaction between rofecoxib and methotrexate in rheumatoid arthritis patients.

  Journal of clinical pharmacology 20011001

• Transport of methotrexate (MTX) and folates by multidrug resistance protein (MRP) 3 and MRP1: effect of polyglutamylation on MTX transport.

  Cancer research 20011001

• Drug-induced pneumonitis: the role of methotrexate.

  Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG 20011001

• Attribution of posttransplantation toxicity to methotrexate regarding genotype of methylenetetrahydrofolate reductase gene (MTHFR) polymorphism needs further clarification.

  Blood 20011001

• Pharmacokinetics and toxicity of intravitreal chemotherapy for primary intraocular lymphoma.

  Archives of ophthalmology (Chicago, Ill. : 1960) 20011001

• Experimental therapeutics with a new 10-deazaaminopterin in human mesothelioma: further improving efficacy through structural design, pharmacologic modulation at the level of MRP ATPases, and combined therapy with platinums.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20011001

• Medroxyprogesterone acetate alone or synergistic with chemotherapy suppresses colony formation and DNA synthesis in C6 glioma in vitro.

  International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20011001

• Leflunomide for the treatment of systemic lupus erythematosus: comment on the article by McMurray.

  Arthritis and rheumatism 20011001

• Inflammation and damage in an individual joint predict further damage in that joint in patients with early rheumatoid arthritis.

  Arthritis and rheumatism 20011001

• [Chorea in pediatric LES. A case report].

  Minerva pediatrica 20011001

• [Treatment of steroid-resistant polymyositis and dermatomyositis].

  Nihon rinsho. Japanese journal of clinical medicine 20011001

• [Methotrexate-ciprofloxacin interaction: report of two cases of severe intoxication].

  Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20011001

• [Transeptal steroids in necrotizing scleritis].

  Archivos de la Sociedad Espanola de Oftalmologia 20011001

• Nutritional regulation of homocysteine: effects of drugs.

  Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20011001

• Sex-related differences in the renal disposition of the acidic metabolite of clentiazem in rat.

  Xenobiotica; the fate of foreign compounds in biological systems 20011001

• A fludarabine-based dose-reduced conditioning regimen followed by allogeneic stem cell transplantation from related or unrelated donors in patients with myelodysplastic syndrome.

  Bone marrow transplantation 20011001

• Donor cell-derived acute myeloid leukemia developing 14 months after matched unrelated bone marrow transplantation for chronic myeloid leukemia.

  Bone marrow transplantation 20011001

• Subcutaneous infection with Mycobacterium fortuitum after allogeneic bone marrow transplantation.

  Bone marrow transplantation 20011001

• [A case of advanced gastric cancer with multiple liver metastases partially responding to combination intra-arterial chemotherapy via the hepatic artery and abdominal aorta].

  Gan to kagaku ryoho. Cancer & chemotherapy 20011001

• [A case of locally advanced breast cancer treated with hyperthermia in combination with radiotherapy].

  Gan to kagaku ryoho. Cancer & chemotherapy 20011001

• [A case of recurring breast cancer causing pericardial metastasis showing a good response following local treatment with methotrexate].

  Gan to kagaku ryoho. Cancer & chemotherapy 20011001

• [Clinical experience of intra-arterial chemotherapy for liver metastases of breast cancer patients].

  Gan to kagaku ryoho. Cancer & chemotherapy 20011001

• [Pharmacokinetics of 'subselective' arterial infusion chemotherapy].

  Gan to kagaku ryoho. Cancer & chemotherapy 20011001

• Co-amplification of dhfr and a homologue of hmsh3 in a Chinese hamster methotrexate-resistant cell line correlates with resistance to a range of chemotherapeutic drugs.

  Cancer chemotherapy and pharmacology 20011001

• FK506 is superior to methotrexate in therapeutic effects on advanced stage of rat adjuvant-induced arthritis.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20011001

• HT29-MTX and Caco-2/TC7 monolayers as predictive models for human intestinal absorption: role of the mucus layer.

  Journal of pharmaceutical sciences 20011001

• [New therapy developments in rheumatoid arthritis].

  Zeitschrift fur Rheumatologie 20011001

• Multiple herpes simplex virus infections with various resistance patterns in a matched unrelated donor transplant recipient.

  Bone marrow transplantation 20011001

• Childhood acute lymphoblastic leukemia: prognostic value of initial peripheral blast count in good responders to prednisone.

  Journal of pediatric hematology/oncology 20011001

• [Treatment of rheumatoid arthritis by inhibition of tumor necrosis factor with infliximab or etanercept].

  Nederlands tijdschrift voor geneeskunde 20010929

• Delivering adjuvant chemotherapy to women with early-stage breast carcinoma: current patterns of care.

  Cancer 20010915

• Transport of cyclic nucleotides and estradiol 17-beta-D-glucuronide by multidrug resistance protein 4. Resistance to 6-mercaptopurine and 6-thioguanine.

  The Journal of biological chemistry 20010907

• Flow cytometry: an improved method for the selection of highly productive gene-amplified CHO cells using flow cytometry.

  Biotechnology and bioengineering 20010905

• New chemotherapy combinations for advanced bladder cancer.

  Current opinion in urology 20010901

• Second-line treatment of advanced transitional cell carcinoma of the urothelial tract.

  Current opinion in urology 20010901

• Isolation of rat dihydrofolate reductase gene and characterization of recombinant enzyme.

  Antimicrobial agents and chemotherapy 20010901

• Evaluation of site-directed spin labeling for characterizing protein-ligand complexes using simulated restraints.

  Biophysical journal 20010901

• Methotrexate suppresses NF-kappaB activation through inhibition of IkappaBalpha phosphorylation and degradation.

  Journal of immunology (Baltimore, Md. : 1950) 20010901

• Functional interactions between arginine-133 and aspartate-88 in the human reduced folate carrier: evidence for a charge-pair association.

  The Biochemical journal 20010901

• Role of kidney-specific organic anion transporters in the urinary excretion of methotrexate.

  Kidney international 20010901

• Co-existent sickle cell disease and juvenile rheumatoid arthritis. Two cases with delayed diagnosis and severe destructive arthropathy.

  The Journal of rheumatology 20010901

• Endocarditis in adult onset Still's disease: a 12 month followup.

  The Journal of rheumatology 20010901

• Sensitivity of soft tissue sarcoma cell lines to chemotherapeutic agents: identification of ecteinascidin-743 as a potent cytotoxic agent.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20010901

• Therapeutic drug monitoring of cytotoxic drugs.

  British journal of clinical pharmacology 20010901

• Specificity of drug transport mediated by CaMDR1: a major facilitator of Candida albicans.

  Journal of biosciences 20010901

• Low-dose chemotherapy with methotrexate and vinblastine for patients with advanced aggressive fibromatosis.

  Cancer 20010901

• [Relapsing polychondritis associated with meningoencephalitis: case report].

  Arquivos de neuro-psiquiatria 20010901

• Effect of probenecid on ventricular cerebrospinal fluid methotrexate pharmacokinetics after intralumbar administration in nonhuman primates.

  Cancer chemotherapy and pharmacology 20010901

• Two-year, blinded, randomized, controlled trial of treatment of active rheumatoid arthritis with leflunomide compared with methotrexate. Utilization of Leflunomide in the Treatment of Rheumatoid Arthritis Trial Investigator Group.

  Arthritis and rheumatism 20010901

• Randomized, open-label, phase II trial of oral capecitabine (Xeloda) vs. a reference arm of intravenous CMF (cyclophosphamide, methotrexate and 5-fluorouracil) as first-line therapy for advanced/metastatic breast cancer.

  Annals of oncology : official journal of the European Society for Medical Oncology 20010901

• HER-2/neu overexpression and in vitro chemosensitivity to CMF and FEC in primary breast cancer.

  Breast cancer research and treatment 20010901

• Chemotherapy-induced bullous acral erythema in a subject with B-cell lymphoma.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20010901

• Antifolate resistance and its circumvention by new analogues.

  Human cell 20010901

• [Prospective randomized trial on the efficacy of adjuvant endocrine therapy for ER-positive breast cancer patients after radical mastectomy].

  Zhonghua zhong liu za zhi [Chinese journal of oncology] 20010901

• Idiopathic hypereosinophilic syndrome: a report of four cases in Arabs, and a review of the literature.

  African journal of medicine and medical sciences 20010901

• Dual role of vitamin C on lipid profile and combined application of cyclophosphamide, methotrexate and 5-fluorouracil treatment in fibrosarcoma-bearing rats.

  Cancer letters 20010828

• Primary central nervous system T-cell lymphoma.

  Neurology 20010828

• [Leflunomide plus methotrexate. Hope for patients with rheumatoid arthritis].

  MMW Fortschritte der Medizin 20010823

• Separation of selected anticancer drugs using superheated water as the mobile phase.

  Analytical chemistry 20010815

• Anti-inflammatory mechanisms of methotrexate in rheumatoid arthritis.

  Annals of the rheumatic diseases 20010801

• Sore throat and hyperferritinaemia.

  Journal of the Royal Society of Medicine 20010801

• Can expression of apoptosis genes, bcl-2 and bax, predict survival and responsiveness to chemotherapy in node-negative breast cancer patients?

  The Journal of surgical research 20010801

• CMF (cyclophosphamide, methotrexate, 5-fluorouracil) versus cnf (cyclophosphamide, mitoxantrone, 5-fluorouracil) as adjuvant chemotherapy for stage II lymph-node positive breast cancer: a phase III randomized multicenter study.

  American journal of clinical oncology 20010801

• Bone marrow failure from medication error: diagnosis by history, not biopsy.

  Archives of internal medicine 20010801

• Influence of adjuvant chemotherapy with cyclophosphamide, methotrexate and 5-fluorouracil on plasma melatonin and chosen hormones in breast cancer premenopausal patients.

  Journal of clinical pharmacy and therapeutics 20010801

• Methotrexate inhibits rheumatoid synovitis by inducing apoptosis.

  The Journal of rheumatology 20010801

• [A case of nonresectable scirrhous type gastric cancer treated by hypertensive subselective chemotherapy with pharmacokinetic modulating chemotherapy].

  Gan to kagaku ryoho. Cancer & chemotherapy 20010801

• Autologous peripheral blood stem cell transplantation in patients with relapsed lymphoma results in accelerated haematopoietic reconstitution, improved quality of life and cost reduction compared with bone marrow transplantation: the Hovon 22 study.

  British journal of haematology 20010801

• Intensification of salvage treatment with high-dose sequential chemotherapy improves the outcome of patients with refractory or relapsed aggressive non-Hodgkin's lymphoma.

  British journal of haematology 20010801

• Weekly intravenous methotrexate with folinic acid for nonmetastatic gestational trophoblastic neoplasia.

  Gynecologic oncology 20010801

• Protective effect of a synthetic analog of prostaglandin E(1) on the small intestinal damage induced by the administration of methotrexate to rats.

  Journal of pharmaceutical sciences 20010801

• Atypical retinal microvasculopathy after bone marrow transplantation.

  Clinical & experimental ophthalmology 20010801

• Severe oral manifestations of chronic graft-vs.-host disease.

  Journal of the American Dental Association (1939) 20010801

• Establishment of a consistent L929 bioassay system for TNF-alpha quantitation to evaluate the effect of lipopolysaccharide, phytomitogens and cytodifferentiation agents on cytotoxicity of TNF-alpha secreted by adherent human mononuclear cells.

  Mediators of inflammation 20010801

• HER-2 and topo-isomerase IIalpha as predictive markers in a population of node-positive breast cancer patients randomly treated with adjuvant CMF or epirubicin plus cyclophosphamide.

  Annals of oncology : official journal of the European Society for Medical Oncology 20010801

• Correlation between decreased apoptosis and multidrug resistance (MDR) in murine leukemic T cell lines.

  Leukemia & lymphoma 20010801

• Ultrastructural and biosynthetic characteristics of epidermal cells in patients with psoriasis treated with antiproliferative drugs.

  Bulletin of experimental biology and medicine 20010801

• Optimum anthracycline-based chemotherapy for early breast cancer.

  The Lancet. Oncology 20010801

• Therapeutic advances in the management of metastatic colorectal cancer.

  Expert review of anticancer therapy 20010801

• Role of Bax in apoptosis of IL-3-dependent cells.

  Oncogene 20010727

• Acquired pure red cell aplasia associated with lymphoproliferative disease of granular T lymphocytes.

  Blood 20010715

• Characteristics of transport of fluoresceinated methotrexate in rat small intestine.

  Life sciences 20010706

• Synthesis and biological activity of 7-oxo substituted analogues of 5-deaza-5,6,7,8-tetrahydrofolic acid (5-DATHF) and 5,10-dideaza-5,6,7,8-tetrahydrofolic acid (DDATHF).

  Journal of medicinal chemistry 20010705

• Early onset Pneumocystis carinii pneumonia after allogeneic peripheral blood stem cell transplantation.

  American journal of hematology 20010701

• Long-term cerebral metabolite changes on proton magnetic resonance spectroscopy in patients cured of acute lymphoblastic leukemia with previous intrathecal methotrexate and cranial irradiation prophylaxis.

  International journal of radiation oncology, biology, physics 20010701

• Follicular mycosis fungoides: a case report and review of the literature.

  Journal of cutaneous pathology 20010701

• Mechanism of folate transport across the human colonic basolateral membrane.

  American journal of physiology. Gastrointestinal and liver physiology 20010701

• Combined systemic and intraventricular chemotherapy in primary CNS lymphoma: a pilot study.

  Journal of neurology, neurosurgery, and psychiatry 20010701

• Pharmacogenetics of methotrexate: toxicity among marrow transplantation patients varies with the methylenetetrahydrofolate reductase C677T polymorphism.

  Blood 20010701

• Delay of the diagnostic lumbar puncture and intrathecal chemotherapy in children with acute lymphoblastic leukemia who undergo routine corticosteroid testing: Tokyo Children's Cancer Study Group study L89-12.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010701

• Adjuvant high-dose medroxyprogesterone acetate for early breast cancer: 13 years update in a multicentre randomized trial.

  British journal of cancer 20010701

• Metastatic placental site trophoblastic tumors: clinical aspects of two unique cases.

  Acta obstetricia et gynecologica Scandinavica 20010701

• Prognostic factors for survival and bladder recurrence in transitional cell carcinoma of the upper urinary tract.

  International journal of urology : official journal of the Japanese Urological Association 20010701

• The impact of p53 status on cellular sensitivity to antifolate drugs.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20010701

• A comparison of early intensive methotrexate/mercaptopurine with early intensive alternating combination chemotherapy for high-risk B-precursor acute lymphoblastic leukemia: a Pediatric Oncology Group phase III randomized trial.

  Leukemia 20010701

• Effect of folic or folinic acid supplementation on the toxicity and efficacy of methotrexate in rheumatoid arthritis: a forty-eight week, multicenter, randomized, double-blind, placebo-controlled study.

  Arthritis and rheumatism 20010701

• Outcome of acute lymphoblastic leukemia in children with AL90 regimen: impact of response to treatment and sex difference on prognostic factors.

  Medical and pediatric oncology 20010701

• [Fatal outcome of a multisystemic sarcoidosis in a 54-year-old patient].

  Pneumologie (Stuttgart, Germany) 20010701

• Combination chemotherapy containing mitoguazone, ifosfamide, methotrexate, etoposide (MIME) and G-CSF efficiently mobilize peripheral blood progenitor cells in heavily pre-treated relapsed lymphoma patients.

  European journal of haematology. Supplementum 20010701

• Ifosfamide- and etoposide-based chemotherapy as salvage and mobilizing regimens for poor prognosis lymphoma.

  European journal of haematology. Supplementum 20010701

• LDL induced association of anionic liposomes with cells and delivery of contents as shown by the increase in potency of liposome dependent drugs.

  Pharmaceutical research 20010701

• Do corticosteroids add any benefit to standard GVHD prophylaxis in allogeneic BMT?

  Bone marrow transplantation 20010701

• Treatment of acute promyelocytic leukaemia using a combination of all-trans retinoic acid and chemotherapy.

  Annals of the Academy of Medicine, Singapore 20010701

• [A case of SLE presenting the features of antiphospholipid antibody syndrome during a treatment for complicated cryptococcal meningitis].

  No to shinkei = Brain and nerve 20010701

• [Intravascular lymphomatosis: a case report].

  No shinkei geka. Neurological surgery 20010701

• Repetitious appearance and disappearance of different kinds of clonal cytogenetic abnormalities after allogeneic bone marrow transplantation.

  International journal of hematology 20010701

• [Typical forms of choriocarcinoma in clinical practice--diagnosis and therapeutic course in four patients].

  Zentralblatt fur Gynakologie 20010701

• The treatment of juvenile arthritis.

  Expert opinion on pharmacotherapy 20010701

• New developments in the prophylaxis and treatment of graft versus host disease.

  Expert opinion on pharmacotherapy 20010701

• A clinical study to determine the efficacy and safety of 1% methotrexate/Azone (MAZ) gel applied topically once daily in patients with psoriasis vulgaris.

  International journal of dermatology 20010701

• FLASHFLOOD: a 3D field-based similarity search and alignment method for flexible molecules.

  Journal of computer-aided molecular design 20010701

• Prognostic impact of CD45 antigen expression in high-risk, childhood B-cell precursor acute lymphoblastic leukemia.

  Leukemia & lymphoma 20010701

• Discussion. Treatment algorithm: managing rheumatoid arthritis.

  Managed care (Langhorne, Pa.) 20010701

• Advanced bladder cancer in a young female: a case report.

  The Tokai journal of experimental and clinical medicine 20010701

• Meta-analysis of adjuvant cyclophosphamide/methotrexate/5-fluorouracil chemotherapy in postmenopausal women with estrogen receptor-positive, node-positive breast cancer.

  Clinical breast cancer 20010701

• [Lymphedema of the upper limb, a complication of rheumatoid polyarthritis].

  Presse medicale (Paris, France : 1983) 20010630

• Randomized adjuvant chemotherapy trial in high-risk, lymph node-negative breast cancer patients identified by urokinase-type plasminogen activator and plasminogen activator inhibitor type 1.

  Journal of the National Cancer Institute 20010620

• Phase III trial comparing two dose levels of epirubicin combined with cyclophosphamide with cyclophosphamide, methotrexate, and fluorouracil in node-positive breast cancer.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010615

• Analysis of the prognostic effects of inclusion in a clinical trial and of myelosuppression on survival after adjuvant chemotherapy for breast carcinoma.

  Cancer 20010615

• Synthesis, antifolate, and antitumor activities of classical and nonclassical 2-amino-4-oxo-5-substituted-pyrrolo[2,3-d]pyrimidines.

  Journal of medicinal chemistry 20010607

• Reduction of telomerase activity in human liver cancer cells by a histone deacetylase inhibitor.

  Journal of cellular physiology 20010601

• Reversal of neurologic disturbances related to high-dose methotrexate by aminophylline.

  Medical and pediatric oncology 20010601

• Comparative study of intramuscular gold and methotrexate in a rheumatoid arthritis population from a socially deprived area.

  Annals of the rheumatic diseases 20010601

• A preclinical model for experimental chemotherapy of human head and neck cancer.

  International journal of oncology 20010601

• Nephrotoxicants induce endothelin release and signaling in renal proximal tubules: effect on drug efflux.

  Molecular pharmacology 20010601

• Western and Chinese antirheumatic drug-induced T cell apoptotic DNA damage uses different caspase cascades and is independent of Fas/Fas ligand interaction.

  Journal of immunology (Baltimore, Md. : 1950) 20010601

• The Société Française d'Oncologie Pédiatrique LMB89 protocol: highly effective multiagent chemotherapy tailored to the tumor burden and initial response in 561 unselected children with B-cell lymphomas and L3 leukemia.

  Blood 20010601

• Bleomycin, methotrexate, and CCNU in locally advanced or recurrent, inoperable, squamous-cell carcinoma of the vulva: an EORTC Gynaecological Cancer Cooperative Group Study. European Organization for Research and Treatment of Cancer.

  Gynecologic oncology 20010601

• Pteridine reductase mechanism correlates pterin metabolism with drug resistance in trypanosomatid parasites.

  Nature structural biology 20010601

• Long-term prognosis of breast cancer patients with 10 or more positive lymph nodes treated with CMF.

  European journal of cancer (Oxford, England : 1990) 20010601

• Different effects of methotrexate on DNA mismatch repair proficient and deficient cells.

  European journal of cancer (Oxford, England : 1990) 20010601

• 1H NMR visible lipids are induced by phosphonium salts and 5-fluorouracil in human breast cancer cells.

  Magnetic resonance in medicine 20010601

• Combined chemo- and radiotherapy vs. radiotherapy alone in the treatment of primary, nonresectable adenocarcinoma of the rectum.

  International journal of radiation oncology, biology, physics 20010601

• CHOD/BVAM regimen plus radiotherapy in patients with primary CNS non-Hodgkin's lymphoma.

  International journal of radiation oncology, biology, physics 20010601

• The history of folic acid.

  British journal of haematology 20010601

• Effect of endocrine treatment on sexuality in premenopausal breast cancer patients: a prospective randomized study.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010601

• Effects of overexpression of gamma-Glutamyl hydrolase on methotrexate metabolism and resistance.

  Cancer research 20010601

• Sp1 involvement in the 4beta-phorbol 12-myristate 13-acetate (TPA)-mediated increase in resistance to methotrexate in Chinese hamster ovary cells.

  European journal of biochemistry 20010601

• Disease modifying antirheumatic drugs: longterm safety issues.

  The Journal of rheumatology. Supplement 20010601

• Conventional DMARD options for patients with a suboptimal response to methotrexate.

  The Journal of rheumatology. Supplement 20010601

• Magnetic resonance imaging detection of avascular necrosis of the bone in children receiving intensive prednisone therapy for acute lymphoblastic leukemia or non-Hodgkin lymphoma.

  Leukemia 20010601

• Daunorubicin continuous infusion induces more toxicity than bolus infusion in acute lymphoblastic leukemia induction regimen: a randomized study.

  Leukemia 20010601

• High level resistance to glucocorticoids, associated with a dysfunctional glucocorticoid receptor, in childhood acute lymphoblastic leukemia cells selected for methotrexate resistance.

  Leukemia 20010601

• Therapeutic strategies: rotational therapy and combinations.

  Clinical and experimental dermatology 20010601

• Homocysteine modulation as a reason for continuous folic acid supplementation in methotrexate-treated rheumatoid arthritis patients.

  Rheumatology (Oxford, England) 20010601

• Metabolic functions of the liver during chemotherapy in children with acute lymphoblastic leukemia.

  International journal of clinical pharmacology and therapeutics 20010601

• Neoadjuvant chemotherapy for patients with synchronous multifocal osteosarcoma: results in eleven cases.

  Journal of chemotherapy (Florence, Italy) 20010601

• Amelioration of steroid-resistant chronic graft-versus-host-mediated liver disease via tacrolimus treatment.

  Journal of hematotherapy & stem cell research 20010601

• Management of inoperable carcinoma of the breast by curative radiotherapy and chemo-hormonotherapy.

  Onkologie 20010601

• Nonmyeloablative hematopoietic cell transplantation. Replacing high-dose cytotoxic therapy by the graft-versus-tumor effect.

  Annals of the New York Academy of Sciences 20010601

• Successful rescue with leucovorin and thymidine in a patient with high-dose methotrexate induced acute renal failure.

  Cancer chemotherapy and pharmacology 20010601

• Treatment of metastatic pancreatic adenocarcinoma: a comprehensive review.

  The Surgical clinics of North America 20010601

• Gastric linitis adenocarcinoma and carcinomatous meningitis: an infrequent but aggressive association--report of four cases.

  Annals of oncology : official journal of the European Society for Medical Oncology 20010601

• Prophylaxis of graft-versus-host disease with cyclosporine-prednisone is associated with increased risk of chronic graft-versus-host disease.

  Bone marrow transplantation 20010601

• [Chronic polyarthritis].

  MMW Fortschritte der Medizin 20010524

• [Methotrexate].

  Deutsche medizinische Wochenschrift (1946) 20010518

• Standard chemotherapy for gastric carcinoma: is it a myth?

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010515

• Flexible alignment of small molecules.

  Journal of medicinal chemistry 20010510

• Isolation of a family of organic anion transporters from human liver and kidney.

  Biochemical and biophysical research communications 20010504

• Treatment with cyclosporin switching to hydroxychloroquine in patients with rheumatoid arthritis.

  Annals of the rheumatic diseases 20010501

• Mutational analysis of the functional role of conserved arginine and lysine residues in transmembrane domains of the murine reduced folate carrier.

  Molecular pharmacology 20010501

• Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney.

  Molecular pharmacology 20010501

• Exercise reduces daily fatigue in women with breast cancer receiving chemotherapy.

  Medicine and science in sports and exercise 20010501

• Leflunomide and methotrexate.

  Current opinion in rheumatology 20010501

• Case reports and small case series: scleritis occurring in association with Takayasu disease.

  Archives of ophthalmology (Chicago, Ill. : 1960) 20010501

• Histologic response of high-grade nonmetastatic osteosarcoma of the extremity to chemotherapy,

  Clinical orthopaedics and related research 20010501

• American College of Rheumatology criteria for improvement in rheumatoid arthritis should only be calculated from scores that decrease on improvement.

  Arthritis and rheumatism 20010501

• Etanercept combined with conventional treatment in Wegener's granulomatosis: a six-month open-label trial to evaluate safety.

  Arthritis and rheumatism 20010501

• Early medical abortion with methotrexate and misoprostol.

  Obstetrics and gynecology 20010501

• Novel therapies for chronic myelogenous leukemia.

  Experimental hematology 20010501

• Mycophenolate Mofetil in the treatment of acute and chronic GVHD in hematopoietic stem cell transplant patients: four years of experience.

  Transplantation proceedings 20010501

• Conventional treatment of Crohn's disease: objectives and outcomes.

  Inflammatory bowel diseases 20010501

• Approach to corticosteroid-dependent and corticosteroid-refractory Crohn's disease.

  Inflammatory bowel diseases 20010501

• Methotrexate versus hyperosomolar glucose in the treatment of extrauterine pregnancy.

  Archives of gynecology and obstetrics 20010501

• Estrogen-receptor-directed neoadjuvant therapy for breast cancer: results of a randomised trial using formestane and methotrexate, mitozantrone and mitomycin C (MMM) chemotherapy.

  Annals of oncology : official journal of the European Society for Medical Oncology 20010501

• Physicochemical parameters responsible for the affinity of methotrexate analogs for rat canalicular multispecific organic anion transporter (cMOAT/MRP2).

  Pharmaceutical research 20010501

• Current concepts regarding pharmacologic treatment of rheumatoid and osteoarthritis.

  Hand clinics 20010501

• Treatment of psoriasis in the Nordic countries: a questionnaire survey from 5739 members of the psoriasis associations data from the Nordic Quality of Life Study.

  Acta dermato-venereologica 20010501

• [A case of sarcoidosis acutely aggravated with high fever and diffuse interstitial pulmonary infiltrates].

  Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20010501

• Folinic acid protects against suppression of growth by methotrexate in mice.

  Biopharmaceutics & drug disposition 20010501

• Immunologic therapy for relapsing-remitting multiple sclerosis.

  Current neurology and neuroscience reports 20010501

• FlexE: efficient molecular docking considering protein structure variations.

  Journal of molecular biology 20010427

• Rational use of new and existing disease-modifying agents in rheumatoid arthritis.

  Annals of internal medicine 20010417

• A combination of etanercept and methotrexate for the treatment of refractory juvenile idiopathic arthritis: a pilot study.

  Annals of the rheumatic diseases 20010401

• Carrier-mediated hepatobiliary transport of a novel antifolate, N-[4-[(2,4-dianninopteridine-6-yl)methyl]-3,4-dihydro-2H-1,4-benzothiazin-7-yl]carbonyl-L-homoglutamic acid, in rats.

  Drug metabolism and disposition: the biological fate of chemicals 20010401

• Hepatic dysfunction in children with acute lymphoblastic leukemia in remission: relation to hepatitis infection.

  Medical and pediatric oncology 20010401

• Primary high-grade mucosa-associated lymphoid tissue-type lymphoma of the cervix presenting as a common endocervical polyp.

  Archives of pathology & laboratory medicine 20010401

• In vitro cytotoxic effects of a tyrosine kinase inhibitor STI571 in combination with commonly used antileukemic agents.

  Blood 20010401

• Results of an outpatient-based stem cell allotransplant program using nonmyeloablative conditioning regimens.

  American journal of hematology 20010401

• Lenograstim and filgrastim effects on neutrophil motility in patients undergoing chemotherapy: evaluation by computer-assisted image analysis.

  American journal of hematology 20010401

• Value of high-dose cytarabine during interval therapy of a Berlin-Frankfurt-Munster-based protocol in increased-risk children with acute lymphoblastic leukemia and lymphoblastic lymphoma: results of the European Organization for Research and Treatment of Cancer 58881 randomized phase III trial.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010401

• Treatment of Behçet's disease--an update.

  Seminars in arthritis and rheumatism 20010401

• Pharmacokinetics of nimustine, cytosine arabinoside, and methotrexate in cerebrospinal fluid during cerebrospinal fluid perfusion chemotherapy.

  Biological & pharmaceutical bulletin 20010401

• 5-fluorouracil modulated by leucovorin, methotrexate and mitomycin: highly effective, low-cost chemotherapy for advanced colorectal cancer.

  British journal of cancer 20010401

• Combination chemotherapy with mitoxantrone, methotrexate, and mitomycin (MMM regimen) in malignant pleural mesothelioma: a phase II study.

  American journal of clinical oncology 20010401

• Treatment of Felty's syndrome with leflunomide.

  The Journal of rheumatology 20010401

• Determinants of outcome after intensified therapy of childhood lymphoblastic leukaemia: results from Medical Research Council United Kingdom acute lymphoblastic leukaemia XI protocol.

  British journal of haematology 20010401

• Combination therapy with tacrolimus and anti-thymocyte globulin for the treatment of steroid-resistant acute graft-versus-host disease developing during cyclosporine prophylaxis.

  British journal of haematology 20010401

• [A case of successful management of nonresectable pancreas cancer with liver metastasis by intra-arterial infusion chemotherapy with angiotensin-II and administration of tegafur/uracil].

  Gan to kagaku ryoho. Cancer & chemotherapy 20010401

• Intra-arterial plus i.v. chemotherapy for advanced bulky squamous cell carcinoma of the buccal mucosa.

  Anti-cancer drugs 20010401

• Immunomodulatory drugs for multiple sclerosis: a systematic review of clinical and cost effectiveness.

  Expert opinion on pharmacotherapy 20010401

• Long-term outcome of treatment with protocols AL841, AL851, and ALHR88 in children with acute lymphoblastic leukemia: results obtained by the Kyushu-Yamaguchi Children's Cancer Study Group.

  International journal of hematology 20010401

• Very empirical treatment of solvation and entropy: a force field derived from log Po/w.

  Journal of computer-aided molecular design 20010401

• [Randomized trial on the effect of radiotherapy in addition to 6 cycles CMF in node-positive breast cancer].

  Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique 20010401

• [Long-term results of a randomized trial comparing breast-conserving therapy with mastectomy: European Organization for Research and Treatment of Cancer 10801 trial].

  Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique 20010401

• Effects of FK506 and other immunosuppressive anti-rheumatic agents on T cell activation mediated IL-6 and IgM production in vitro.

  International immunopharmacology 20010401

• Gemcitabine in advanced bladder cancer.

  Seminars in oncology 20010401

• Treatment of metastatic urothelial cancer in the post-MVAC era.

  World journal of urology 20010401

• [Low dose steroid therapy in rheumatoid arthritis: a model for therapy of inflammatory diseases?--Results of the LDPT Study].

  Zeitschrift fur Rheumatologie 20010401

• Protective effect of folinic acid on low-dose methotrexate genotoxicity.

  Zeitschrift fur Rheumatologie 20010401

• [Study of neoadjuvant chemotherapy for invasive bladder cancer with MEC (methotrexate, epirubicin, cisplatin) therapy].

  Hinyokika kiyo. Acta urologica Japonica 20010401

• [MTX/5FU sequential therapy for advanced and recurrent gastric cancer].

  Nihon rinsho. Japanese journal of clinical medicine 20010401

• ACOG Practice Bulletin. Clinical management guidelines for obstetrician-gynecologists. Medical management of abortion.

  Obstetrics and gynecology 20010401

• Breast cancer survival and in vitro tumor response in the extreme drug resistance assay.

  Breast cancer research and treatment 20010401

• Leflunomide and rheumatoid arthritis: new preparation. Neither the safest nor the most effective slow-acting antirheumatic drug.

  Prescrire international 20010401

• Occult breast cancer and axillary mass.

  Current treatment options in oncology 20010401

• Operable breast cancer.

  Current treatment options in oncology 20010401

• [Study on effect of moxibustion and guben yiliu III combined with chemotherapy in treating middle-late stage malignant tumor].

  Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20010401

• Rescue of embryonic lethality in reduced folate carrier-deficient mice by maternal folic acid supplementation reveals early neonatal failure of hematopoietic organs.

  The Journal of biological chemistry 20010330

• Repression of human reduced folate carrier gene expression by wild type p53.

  The Journal of biological chemistry 20010323

• Randomized trials of high dose chemotherapy for breast cancer.

  Biochimica et biophysica acta 20010321

• Competing risks analysis of patients with osteosarcoma: a comparison of four different approaches.

  Statistics in medicine 20010315

• Association of deletions and translocation of the reduced folate carrier gene with profound loss of gene expression in methotrexate-resistant K562 human erythroleukemia cells.

  Biochemical pharmacology 20010315

• High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes.

  Journal of medicinal chemistry 20010315

• Target analogue imprinted polymers with affinity for folic acid and related compounds.

  Journal of the American Chemical Society 20010314

• [Sarcoidosis].

  Medicina clinica 20010303

• Methotrexate and early postoperative complications in patients with rheumatoid arthritis undergoing elective orthopaedic surgery.

  Annals of the rheumatic diseases 20010301

• Inappropriate medical management of spinal epidural abscess.

  Annals of the rheumatic diseases 20010301

• Novel therapies for anti-neutrophil cytoplasmic antibody-associated vasculitis.

  Current opinion in nephrology and hypertension 20010301

• The three modules of ADP/ATP carrier cooperate in receptor recruitment and translocation into mitochondria.

  The EMBO journal 20010301

• Synergistic efficacy of 3n-butyrate and 5-fluorouracil in human colorectal cancer xenografts via modulation of DNA synthesis.

  Gastroenterology 20010301

• Expression of apoptosis-related markers and clinical outcome in patients with advanced colorectal cancer.

  British journal of cancer 20010301

• Adjuvant hysterectomy in low-risk gestational trophoblastic disease.

  Obstetrics and gynecology 20010301

• Fasting hypoglycemia is common during maintenance therapy for childhood acute lymphoblastic leukemia.

  The Journal of pediatrics 20010301

• Motor nervous pathway function is impaired after treatment of childhood acute lymphoblastic leukemia: a study with motor evoked potentials.

  Medical and pediatric oncology 20010301

• Use of methotrexate in the management of sight-threatening uveitis.

  Ocular immunology and inflammation 20010301

• Destructive eyelid lesions in sarcoidosis.

  Ophthalmic plastic and reconstructive surgery 20010301

• Methotrexate stimulates lung fibroblasts and epithelial cells to release eosinophil chemotactic activity.

  The Journal of rheumatology 20010301

• Metastatic placental site trophoblastic tumor. Report of a case with complete response to chemotherapy.

  The Journal of reproductive medicine 20010301

• Immunosuppressive and cytotoxic drugs in the treatment of rheumatic skin disorders.

  Seminars in cutaneous medicine and surgery 20010301

• Management of a patient with sarcoid calcaneitis and dactylitis.

  Joint, bone, spine : revue du rhumatisme 20010301

• The pharmacology of methotrexate.

  Expert opinion on pharmacotherapy 20010301

• How is it best to treat early rheumatoid arthritis patients?

  Best practice & research. Clinical rheumatology 20010301

• [Cisplatin and vinorelbine therapy of previously treated advanced breast cancer (preliminary studies)].

  Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20010301

• Are medical oncologists biased in their treatment of the large woman with breast cancer?

  Breast cancer research and treatment 20010301

• Sample size calculations for the two-sample problem using the multiplicative intensity model.

  Statistics in medicine 20010227

• Topoisomerase II inhibitor induced leukemia in a patient with AIDS.

  AIDS (London, England) 20010216

• Tamoxifen and chemotherapy for axillary node-negative, estrogen receptor-negative breast cancer: findings from National Surgical Adjuvant Breast and Bowel Project B-23.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010215

• Dose-intensive epirubicin-based chemotherapy is superior to an intensive intravenous cyclophosphamide, methotrexate, and fluorouracil regimen in metastatic breast cancer: a randomized multinational study.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010215

• Gemcitabine and cisplatin for advanced, metastatic bladder cancer.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010215

• Current management of rheumatoid arthritis.

  Hospital practice (1995) 20010215

• Thymidine kinase and thymidylate synthase in advanced breast cancer: response to tamoxifen and chemotherapy.

  Cancer research 20010215

• Methotrexate accumulates to similar levels in animals transplanted with normal versus drug-resistant transgenic marrow.

  Cancer research 20010215

• Thymidine utilization abnormality in proliferating lymphocytes and hepatocytes of the woodchuck.

  Veterinary immunology and immunopathology 20010210

• Results of intensive chemotherapy followed by hematopoietic stem-cell rescue in 22 patients with refractory or recurrent primary CNS lymphoma or intraocular lymphoma.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010201

• Survival in patients with intermediate or high grade non-Hodgkin's lymphoma: meta-analysis of randomized studies comparing third generation regimens with CHOP.

  British journal of cancer 20010201

• Testicular relapse in acute promyelocytic leukaemia.

  British journal of haematology 20010201

• No effect of phenobarbital pretreatment of rats on methotrexate pharmacokinetics in the isolated liver perfused in a single-pass way.

  Pharmacology 20010201

• [Can 67Ga citrate predict the efficacy of chemotherapy early in Hodgkin's lymphoma?].

  Revista espanola de medicina nuclear 20010201

• Bone marrow involvement by nasal NK cell lymphoma at diagnosis is uncommon.

  American journal of clinical pathology 20010201

• Hepatic dysfunction as the presenting feature of acute lymphoblastic leukemia.

  Journal of pediatric hematology/oncology 20010201

• Primary central nervous system lymphoma in childhood presenting as progressive panhypopituitarism.

  Journal of pediatric hematology/oncology 20010201

• Current understanding of methotrexate pharmacology and efficacy in acute leukemias. Use of newer antifolates in clinical trials.

  Haematologica 20010201

• Primary mediastinal large B-cell lymphoma with sclerosis: a clinical study of 89 patients treated with MACOP-B chemotherapy and radiation therapy.

  Haematologica 20010201

• Development of fulminant hepatitis B (precore variant mutant type) after the discontinuation of low-dose methotrexate therapy in a rheumatoid arthritis patient.

  Arthritis and rheumatism 20010201

• Prediction of node-negative breast cancer outcome by histologic grading and S-phase analysis by flow cytometry: an Eastern Cooperative Oncology Group Study (2192).

  American journal of clinical oncology 20010201

• Two patients with N3 bladder cancer successfully treated by internal iliac arterial infusion chemotherapy and irradiation: case reports.

  American journal of clinical oncology 20010201

• Neoadjuvant chemotherapy for high grade osteosarcoma of the extremities: long-term results for patients treated according to the Rizzoli IOR/OS-3b protocol.

  Journal of chemotherapy (Florence, Italy) 20010201

• [Psychological and behavioral disorders with good outcome in neurosarcoidosis].

  La Revue de medecine interne 20010201

• Comparison of the L10M consolidation regimen to an alternative regimen including escalating methotrexate/L-asparaginase for adult acute lymphoblastic leukemia: a Southwest Oncology Group Study.

  Leukemia 20010201

• A comparison of methods of loco-regional chemotherapy combined with systemic chemotherapy as neo-adjuvant treatment of osteosarcoma of the extremity.

  European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 20010201

• Induction therapy of adult acute lymphocytic leukemia without the use of vincristine or prednisone.

  Hematology/oncology clinics of North America 20010201

• Misoprostol administration in medical abortion. A comparison of three regimens.

  The Journal of reproductive medicine 20010201

• [Listeria arthritis in chronic polyarthritis during low dose prednisolone and methotrexate therapy. Case report and review of the literature].

  Zeitschrift fur Rheumatologie 20010201

• Alendronate in rheumatoid arthritis patients treated with methotrexate and glucocorticoids.

  Rheumatology international 20010201

• Transient posterior encephalopathy induced by chemotherapy in children.

  Pediatric neurology 20010201

• Psoriatic onycho-pachydermo-periostitis.

  Dermatology online journal 20010201

• [Neurological form of onset in haemophagocytic lymphohistiocytosis].

  Revista de neurologia 20010201

• Early medical abortion with methotrexate and misoprostol: outcomes and satisfaction among women aged 15-21 years.

  Journal of pediatric and adolescent gynecology 20010201

• [Long-term results with MACOP-B and radiation therapy for aggressive lymphomas].

  Onkologie 20010201

• New dermatological agents for the treatment of psoriasis.

  Journal of medicinal chemistry 20010201

• [Combination of mycophenolate mofetil with cyclosporine A and methotrexate as acute GVHD prophylaxis after unrelated donor allogeneic bone marrow transplantation].

  Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20010201

• Crystal structure of the hydrated strontium salt of methotrexate: two independent molecules with different conformations.

  Journal of medicinal chemistry 20010118

• Combined treatment of giant-cell arteritis with methotrexate and prednisone. a randomized, double-blind, placebo-controlled trial.

  Annals of internal medicine 20010116

• Response to cyclophosphamide, methotrexate, and fluorouracil in lymph node-positive breast cancer according to HER2 overexpression and other tumor biologic variables.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010115

• [Treatment of ectopic pregnancy with methotrexate].

  La Revue du praticien 20010115

• Impact of the reduced folate carrier on the accumulation of active thiamin metabolites in murine leukemia cells.

  The Journal of biological chemistry 20010112

• Chorea and antiphospholipid antibodies: treatment with methotrexate.

  Neurology 20010109

• Passive and iontophoretic transdermal penetration of methotrexate.

  International journal of pharmaceutics 20010105

• Misoprostol and pregnancy.

  The New England journal of medicine 20010104

• Therapeutic advances in ankylosing spondylitis.

  Expert opinion on investigational drugs 20010101

• Chemotherapy and marrow transplantation for congenital leukaemia.

  Archives of disease in childhood. Fetal and neonatal edition 20010101

• Diffuse brachial plexopathy after interscalene blockade in a patient receiving cisplatin chemotherapy: the pharmacologic double crush syndrome.

  Anesthesia and analgesia 20010101

• Inhibition of thymidine synthesis by folate analogues induces a Fas-Fas ligand-independent deletion of superantigen-reactive peripheral T cells.

  International immunology 20010101

• Thiols can either enhance or suppress DNA damage induction by catecholestrogens.

  Free radical biology & medicine 20010101

• Efficacy of parenteral methotrexate in refractory Crohn's disease.

  Alimentary pharmacology & therapeutics 20010101

• Primary central nervous system lymphoma 1991-1997: outcome and late adverse effects after combined modality treatment.

  Cancer 20010101

• Factors that influence the penetration of methotrexate through solid tissue.

  International journal of cancer 20010101

• Early medical abortion with methotrexate and misoprostol.

  Obstetrics and gynecology 20010101

• Evolving treatment strategies for inflammatory bowel disease.

  Annual review of medicine 20010101

• Generation of dual resistance to 4-hydroperoxycyclophosphamide and methotrexate by retroviral transfer of the human aldehyde dehydrogenase class 1 gene and a mutated dihydrofolate reductase gene.

  Molecular therapy : the journal of the American Society of Gene Therapy 20010101

• Impact of surgical resection of bladder cancer metastases refractory to systemic therapy on performance score: a phase II trial.

  Urology 20010101

• Should we always choose a nonparametric test when comparing two apparently nonnormal distributions?

  Journal of clinical epidemiology 20010101

• The value of amino-terminal propeptide of type III procollagen in routine screening for methotrexate-induced liver fibrosis: a 10-year follow-up.

  The British journal of dermatology 20010101

• Key determinants in the occurrence of clonal variation in humanized antibody expression of cho cells during dihydrofolate reductase mediated gene amplification.

  Biotechnology progress 20010101

• Schedule-dependent synergism and antagonism between raltitrexed ('Tomudex') and methotrexate in human colon cancer cell lines in vitro.

  Japanese journal of cancer research : Gann 20010101

• Evidence for immune activation against oxidized lipoproteins in inactive phases of juvenile chronic arthritis.

  The Journal of rheumatology 20010101

• SLATE: a method for the superposition of flexible ligands.

  Journal of computer-aided molecular design 20010101

• Biochemical modulation of 5-FU in systemic treatment of advanced colorectal cancer.

  Oncology (Williston Park, N.Y.) 20010101

• Bilateral empyema caused by adult-onset Still's disease.

  Respiration; international review of thoracic diseases 20010101

• [Cholesterol pericarditis associated with rheumatoid arthritis].

  Harefuah 20010101

• 6-mercaptopurine dosage and pharmacokinetics influence the degree of bone marrow toxicity following high-dose methotrexate in children with acute lymphoblastic leukemia.

  Leukemia 20010101

• Combined treatment with high-dose methotrexate, vincristine and procarbazine, without intrathecal chemotherapy, followed by consolidation radiotherapy for primary central nervous system lymphoma in immunocompetent patients.

  Oncology 20010101

• Angiogenesis sustains tumor dormancy in patients with breast cancer treated with adjuvant chemotherapy.

  Breast cancer research and treatment 20010101

• Influence of cyclic intravenous pamidronate on proinflammatory monocytic cytokine profiles and bone density in rheumatoid arthritis treated with low dose prednisolone and methotrexate.

  Clinical and experimental rheumatology 20010101

• Dihydrofolate reductase from Thermotoga maritima.

  Methods in enzymology 20010101

• Testing the role of chain connectivity on the stability and structure of dihydrofolate reductase from E. coli: fragment complementation and circular permutation reveal stable, alternatively folded forms.

  Protein science : a publication of the Protein Society 20010101

• Postsurgical sequential methotrexate/5-FU and leucovorin on outpatient basis for advanced colorectal carcinoma.

  Hepato-gastroenterology 20010101

• Stereoselectivity of the folate transporter in rabbit small intestine: studies with amethopterin enantiomers.

  Chirality 20010101

• Prognostic value of day 14 blast percentage and the absolute blast index in bone marrow of children with acute lymphoblastic leukemia.

  Pediatric hematology and oncology 20010101

• Parotid mucoepidermoid carcinoma following chemotherapy for childhood acute lymphoblastic leukemia.

  Pediatric hematology and oncology 20010101

• Combination chemotherapy of cisplatin, methotrexate, vinblastine, and high-dose tamoxifen for transitional cell carcinoma.

  Anticancer research 20010101

• [Continuous versus intermittent infusion in chemotherapy of colorectal cancer].

  Tumori 20010101

• Old and new drugs used in rheumatoid arthritis: a historical perspective. Part 1: the older drugs.

  American journal of therapeutics 20010101

• Methotrexate therapy in systemic lupus erythematosus.

  Lupus 20010101

• Effect of obesity on the leukocyte nadir in women treated with adjuvant cyclophosphamide, methotrexate, and fluorouracil dosed according to body surface area.

  Acta oncologica (Stockholm, Sweden) 20010101

• Dose-dense sequential adjuvant chemotherapy with epirubicin, paclitaxel and CMF in high-risk breast cancer.

  Oncology 20010101

• [Treatment of uveitis with immunosuppressives: antimetabolites and alkylating agents].

  Bulletin de la Societe belge d'ophtalmologie 20010101

• Renal involvement in juvenile rheumatoid arthritis: report of two cases.

  Clinical rheumatology 20010101

• Intrathecal chemotherapy with antineoplastic agents in children.

  Paediatric drugs 20010101

• Antioxidants as adjuvant therapy in rheumatoid disease. A preliminary study.

  Arzneimittel-Forschung 20010101

• Primary isolated lymphoma of the fourth ventricle: case report.

  Journal of neuro-oncology 20010101

• Hospital resources used for ectopic pregnancy treatment by laparoscopy and methotrexate.

  JSLS : Journal of the Society of Laparoendoscopic Surgeons 20010101

• Infliximab in the treatment of adult Still's disease refractory to conventional therapy.

  Clinical and experimental rheumatology 20010101

• Pilot study using the combination of methotrexate and thalidomide in the treatment of rheumatoid arthritis.

  Clinical and experimental rheumatology 20010101

• Relationship between dose-intensity of treatment and outcome for patients with osteosarcoma of the extremity treated with neoadjuvant chemotherapy.

  Oncology reports 20010101

• Clinical applications of a novel sustained-release injectable drug delivery system: DepoFoam technology.

  Cancer journal (Sudbury, Mass.) 20010101

• Risk-oriented postremission strategies in adult acute lymphoblastic leukemia: prospective confirmation of anthracycline activity in standard-risk class and role of hematopoietic stem cell transplants in high-risk groups.

  The hematology journal : the official journal of the European Haematology Association 20010101

• [Effect of inhibitors of enzymatic DNA methylation on the formation of reproductive structures and carotenoid production in Neurospora crassa].

  Prikladnaia biokhimiia i mikrobiologiia 20010101

• Central nervous system involvement in gestational trophoblastic neoplasia.

  European journal of gynaecological oncology 20010101

• Persistent plaques and linear pigmentation in adult-onset Still's disease.

  Dermatology (Basel, Switzerland) 20010101

• [Fetal aminopterin syndrome].

  Ryoikibetsu shokogun shirizu 20010101

• Parvovirus B19 infection in a child with acute lymphoblastic leukemia during induction therapy.

  Journal of pediatric hematology/oncology 20010101

• Thyroid carcinoma after successful treatment of osteosarcoma: a report of three patients.

  Journal of pediatric hematology/oncology 20010101

• Bilateral subdural effusions related to disease activity in familial hemophagocytic lymphohistiocytosis in an 8-month-old infant.

  Journal of pediatric hematology/oncology 20010101

• Folate supplementation during methotrexate treatment of patients with rheumatoid arthritis. An update and proposals for guidelines.

  Scandinavian journal of rheumatology 20010101

• Successful treatment of bronchiolitis obliterans organizing pneumonia with low-dose methotrexate in a patient with Hodgkin's disease.

  Oncology 20010101

• Benefits of leflunomide in systemic lupus erythematosus: a pilot observational study.

  Lupus 20010101

• Successful treatment of cervical and simultaneous cervico-isthmic pregnancy with methotrexate.

  Clinical and experimental obstetrics & gynecology 20010101

• A case report of a man with rheumatoid factor positive rheumatoid arthritis associated with collagenous colitis.

  Clinical and experimental rheumatology 20010101

• Beneficial effects of leflunomide in glucocorticoid- and methotrexate-resistant Takayasu's arteritis.

  Clinical and experimental rheumatology 20010101

• Sarcoidosis presenting as Heerfordt's syndrome with myopathy.

  Clinical and experimental rheumatology 20010101

• Effect of a synthetic analog of prostaglandin E1 on the intestinal mucosa of methotrexate-treated rats.

  Anticancer research 20010101

• Serial quantitative PCR analysis of bone marrow samples from breast cancer patients to monitor systemic micrometastases.

  Anticancer research 20010101

• [Adjuvant therapy of breast cancer].

  Khirurgiia 20010101

• [Double-blind trial of the effectiveness of antibodies to interferon-gamma and tumor necrosis factor-alpha in rheumatoid arthritis (preliminary results)].

  Terapevticheskii arkhiv 20010101

• [Local injection therapy of rheumatoid arthritis].

  Terapevticheskii arkhiv 20010101

• New therapeutic approaches to the management of rheumatoid arthritis.

  BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 20010101

• [Extracorporeal therapy of rheumatoid arthritis].

  Terapevticheskii arkhiv 20010101

• The effect of drugs and toxins on the process of apoptosis.

  Drug metabolism and drug interactions 20010101

• A randomized, controlled, single-blind trial of leflunomide in the treatment of rheumatoid arthritis.

  Journal of Tongji Medical University = Tong ji yi ke da xue xue bao 20010101

• [Treatment of acute lymphoblastic leukemia in adults as an unsolved problem].

  Terapevticheskii arkhiv 20010101

• Vinorelbine, epirubicin, and methotrexate (VEM) as primary treatment in locally advanced breast cancer.

  The oncologist 20010101

• Molecular and cellular biology of the human reduced folate carrier.

  Progress in nucleic acid research and molecular biology 20010101

• Cutaneous ulceration as a sign of methotrexate toxicity.

  European journal of dermatology : EJD 20010101

• [Effect of chemotherapeutical agents on the structure and function of blood serum albumin in breast cancer].

  Voprosy onkologii 20010101

• British National Lymphoma Investigation: pilot studies of neoadjuvant chemotherapy in clinical stage Ia and IIa Hodgkin's disease.

  Clinical oncology (Royal College of Radiologists (Great Britain)) 20010101

• Presurgical window of carboplatin and surgery and multidrug chemotherapy for the treatment of newly diagnosed metastatic or unresectable osteosarcoma: Pediatric Oncology Group Trial.

  Journal of pediatric hematology/oncology 20010101

• Altered pharmacokinetics and liver targetability of methotrexate by conjugation with lactosylated albumins.

  Drug delivery 20010101

• Differing sensitivity of tumor cells to apoptosis induced by iron deprivation in vitro.

  In vitro cellular & developmental biology. Animal 20010101

• Adjuvant treatment in node-negative, postmenopausal breast cancer.

  Cancer investigation 20010101

• A prospective, double-blind, randomized, placebo controlled trial of methotrexate in the treatment of giant cell arteritis (GCA).

  Clinical and experimental rheumatology 20010101

• Perforin granule release from cytotoxic lymphocytes ex vivo is inhibited by ciclosporin but not by methotrexate.

  Skin pharmacology and applied skin physiology 20010101

• [Conservative therapy in endocrine orbitopathy: 'State of the art'].

  Acta medica Austriaca 20010101

• MR findings in Balint's syndrome, following intrathecal methotrexate and cytarabine therapy in adult acute lymphoblastic leukemia.

  European neurology 20010101

• Recurrent molar pregnancy: report of a case with seven consecutive hydatidiform moles.

  Gynecologic and obstetric investigation 20010101

• [Methotrexate, liver and rheumatoid arthritis in tropical areas].

  Sante (Montrouge, France) 20010101

• Psoriasis in children: a guide to its diagnosis and management.

  Paediatric drugs 20010101

• Neoadjuvant moderately high-dose chemotherapy with rh-G-CSF in locally advanced breast carcinoma.

  Tumori 20010101

• Dose scheduling--Herceptin.

  Oncology 20010101

• New combinations with Herceptin in metastatic breast cancer.

  Oncology 20010101

• MACOP-B regimen followed by involved-field radiation therapy in early-stage aggressive non-Hodgkin's lymphoma patients: 14-year update results.

  Leukemia & lymphoma 20010101

• Therapy of pemphigus.

  Clinics in dermatology 20010101

• Pharmacokinetic considerations in the treatment of inflammatory bowel disease.

  Clinical pharmacokinetics 20010101

• Predictive relevance of soluble CD44v6 serum levels for the responsiveness to second line hormone- or chemotherapy in patients with metastatic breast cancer.

  Anticancer research 20010101

• Chemotherapy and concomitant irradiation in inflammatory breast cancer.

  Anticancer research 20010101

• Rituximab in combination with interferon-alpha in relapsed and refractory diffuse large B-cell non-Hodgkin's lymphoma.

  Acta haematologica 20010101

• Anticipating the future role of radiotherapy and chemotherapy in the treatment of head and neck cancer: a lesson from Manchester.

  Clinical oncology (Royal College of Radiologists (Great Britain)) 20010101

• Treatment of systemic sclerosis.

  American journal of clinical dermatology 20010101

• Clinical investigation of methotrexate in the treatment of ankylosing spondylitis.

  Scandinavian journal of rheumatology 20010101

• Changes in plasma homocysteine in arthritis patients starting treatment with low-dose methotrexate subsequently supplemented with folic acid.

  Scandinavian journal of rheumatology 20010101

• Does mechanical insult to cartilage trigger relapsing polychondritis?

  Scandinavian journal of rheumatology 20010101

• Phase 1/2 study of synchronous methotrexate, cisplatin, vincristine (MOPq10) chemotherapy and radiation for patients with locally advanced bladder cancer.

  Urologia internationalis 20010101

• Nonlinear fatty acid terminated polyanhydrides.

  Biomacromolecules 20010101

• Therapy of PCNSL at the Massachusetts General Hospital with high dose methotrexate and deferred radiotherapy.

  Annals of hematology 20010101

• Therapeutic management of refractory or relapsed primary central nervous system lymphomas.

  Annals of hematology 20010101

• High-dose sequential (HDS) chemotherapy for high-risk non-Hodgkin's lymphoma: long-term analysis and future developments.

  Annals of hematology 20010101

• Favorable outcome for children and adolescents with T-cell lymphoblastic lymphoma with an intensive ALL-type therapy without local radiotherapy.

  Annals of hematology 20010101

• Prolonged blood circulation of methotrexate by modulation of liposomal composition.

  Drug delivery 20010101

• Pyoderma gangrenosum in a patient with psoriatic arthritis.

  The Journal of the American Board of Family Practice 20010101

• Late effects of anticancer therapy on kidney function in children with acute lymphoblastic leukemia.

  Bratislavske lekarske listy 20010101

• Immunomodulating drugs in the management of psoriatic arthritis.

  American journal of clinical dermatology 20010101

• Toxicity of methotrexate treatment in psoriasis and psoriatic arthritis--short- and long-term toxicity in 104 patients.

  Clinical rheumatology 20010101

• Health-related quality of life and its potential prognostic implications in patients with aggressive lymphoma: a Nordic Lymphoma Group Trial.

  Medical oncology (Northwood, London, England) 20010101

• The worldwide perspective in the adjuvant treatment of primary lymph node positive breast cancer.

  Breast cancer (Tokyo, Japan) 20010101

• Polyarteritis nodosa developing after discoid lupus erythematosus.

  Clinical and experimental rheumatology 20010101

• Macrophage activation syndrome as the initial manifestation of systemic onset juvenile idiopathic arthritis.

  Clinical and experimental rheumatology 20010101

• Cellular abundance of es nucleoside transporters and differential drug toxicity in myelodysplastic syndrome (MDS) bone marrow cell subpopulations.

  Proceedings of the Western Pharmacology Society 20010101

• Variability of oral bioavailability for low dose methotrexate in rats.

  European journal of drug metabolism and pharmacokinetics 20010101

• Lacrimal duct stenosis and other ocular toxicity associated with adjuvant cyclophosphamide, methotrexate and 5-fluorouracil combination chemotherapy for early stage breast cancer.

  Clinical oncology (Royal College of Radiologists (Great Britain)) 20010101

• Acute abdomen during adjuvant chemotherapy: superior mesenteric artery thrombosis associated with CMF chemotherapy.

  Clinical oncology (Royal College of Radiologists (Great Britain)) 20010101

• Phase II study of sequential high-dose methotrexate and fluorouracil combined with doxorubicin as a neoadjuvant chemotherapy for scirrhous gastric cancer.

  Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 20010101

• Sequential methotrexate and 5-fluorouracil therapy for gastric cancer patients with peritoneal dissemination: a retrospective study.

  Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 20010101

• Unusual port presentation.

  Clinical journal of oncology nursing 20010101

• [Chemotherapy-associated myelosuppression in gynecological oncology].

  Gynakologisch-geburtshilfliche Rundschau 20010101

• Management of psoriasis vulgaris with methotrexate 0.25% in a hydrophilic gel: a placebo-controlled, double-blind study.

  Journal of cutaneous medicine and surgery 20010101

• Acquisition of multidrug resistance in recurrent breast cancer demonstrated by the histoculture drug response assay.

  Anticancer research 20010101

• Tamoxifen-based treatment induces clinically meaningful responses in multiple myeloma patients with relapsing disease after autotransplantation.

  Leukemia & lymphoma 20010101

• A clinical, molecular and cytogenetic study of 12 cases of human herpesvirus 8 associated primary effusion lymphoma in HIV-infected patients.

  The hematology journal : the official journal of the European Haematology Association 20010101

• Outcome is not improved by the use of alternating chemotherapy in elderly patients with aggressive lymphoma.

  The hematology journal : the official journal of the European Haematology Association 20010101

• Response to low-dose oral methotrexate and prednisone in two patients with angio-immunoblastic lymphadenopathy-type T-cell lymphoma.

  The hematology journal : the official journal of the European Haematology Association 20010101

• Investigations on the biological properties of the lipophilic DHFR-inhibitory benzoprims reveal non-folate modes of action and opportunities for anti-cancer drug design.

  Anti-cancer drug design 20010101

• Adjuvant and neoadjuvant chemotherapy in osteosarcoma.

  La Chirurgia degli organi di movimento 20010101

• [Drug therapy of Crohn disease].

  Duodecim; laaketieteellinen aikakauskirja 20010101

• [Lymphomatoid papulosis--a sheep in wolves' clothes].

  Duodecim; laaketieteellinen aikakauskirja 20010101

• Adjuvant doxorubicin and cyclophosphamide versus cyclophosphamide, methotrexate, and 5-fluorouracil chemotherapy in premenopausal women with axillary lymph node positive breast carcinoma.

  Cancer 20001215

• Atrial fibrillation occurring in a patient taking etanercept plus methotrexate for rheumatoid arthritis.

  Delaware medical journal 20001201

• Methotrexate, uracil and tegafur, and leucovorin chemotherapy for patients with breast cancer in progression after high-dose chemotherapy with peripheral blood progenitor cell transplant: a phase II study.

  American journal of clinical oncology 20001201

• Expression and characterization of recombinant human-derived Pneumocystis carinii dihydrofolate reductase.

  Antimicrobial agents and chemotherapy 20001101

• Acute neurotoxicity in children with B-lineage acute lymphoblastic leukemia (B-ALL) treated with intermediate risk protocols.

  Medical and pediatric oncology 20001101

• White matter changes on MRI during treatment in children with acute lymphoblastic leukemia: correlation with neuropsychological findings.

  Medical and pediatric oncology 20001101

• Serious liver disease in a patient receiving methotrexate and leflunomide.

  Arthritis and rheumatism 20001101

• Design, synthesis, and X-ray crystal structure of a potent dual inhibitor of thymidylate synthase and dihydrofolate reductase as an antitumor agent.

  Journal of medicinal chemistry 20001019

• Treatment for primary CNS lymphoma: the next step.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20000901

• Cutaneous ulcerations in a patient with rheumatoid arthritis receiving treatment with methotrexate.

  The Journal of rheumatology 20000901

• Methotrexate treatment protocols and the central nervous system: significant cure with significant neurotoxicity.

  Journal of child neurology 20000901

• [Carboxypeptidase-G2-rescue in a woman with methotrexate-induced renal failure].

  Medizinische Klinik (Munich, Germany : 1983) 20000815

• [A case of rheumatoid arthritis associated with autoimmune hemolytic anemia due to weekly low-dose methotrexate therapy].

  Ryumachi. [Rheumatism] 20000801

• Impotence in a patient with rheumatoid arthritis treated with methotrexate.

  The Journal of rheumatology 20000701

• Tacrolimus (FK506) and methotrexate as prophylaxis for acute graft-versus-host disease in pediatric allogeneic stem cell transplantation.

  Bone marrow transplantation 20000701

• Cerebral vasculopathy and multiple infarctions in a woman with carcinomatous meningitis while on treatment with intrathecal methotrexate.

  Journal of neuro-oncology 20000501

• Interactions of the human multidrug resistance proteins MRP1 and MRP2 with organic anions.

  Molecular pharmacology 20000401

• Carboxypeptidase G2 rescue in delayed methotrexate elimination in renal failure.

  Leukemia & lymphoma 20000401

• Anthracyclines trigger apoptosis of both G0-G1 and cycling peripheral blood lymphocytes and induce massive deletion of mature T and B cells.

  Cancer research 20000401

• Pneumocystis carinii pneumonia prophylaxis in patients with rheumatic diseases undergoing immunosuppressive therapy: prealence and associated features.

  Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20000401

• Cortical laminar necrosis caused by immunosuppressive therapy and chemotherapy.

  AJNR. American journal of neuroradiology 20000301

• Identification by RNA-based arbitrarily primed PCR of the involvement of cytochrome c oxidase in the development of resistance to methotrexate.

  Biochimica et biophysica acta 20000227

• Manic episode in an ifosfamide-treated patient.

  General hospital psychiatry 20000101

• Influence of cyclosporin A on radiological progression in early rheumatoid arthritis patients: a 42-month prospective study.

  Rheumatology international 20000101

• Cognitive sequelae in children treated for acute lymphoblastic leukemia with dexamethasone or prednisone.

  Journal of pediatric hematology/oncology 20000101

• Hepatocellular carcinoma: a rare late event in childhood acute lymphoblastic leukemia.

  Journal of pediatric hematology/oncology 20000101

• Veno-occlusive disease of the liver associated with thiopurines in a child with acute lymphoblastic leukemia.

  Pediatric hematology and oncology 20000101

• Acute stroke-like encephalopathy associated with high-dose methotrexate impurities.

  Journal of pediatric hematology/oncology 20000101

• Atypical methotrexate dermatitis and vasculitis in a patient with ankylosing spondylitis.

  Rheumatology international 20000101

• Leukocytoclastic vasculitis associated with methotrexate therapy.

  The Turkish journal of pediatrics 20000101

• Serosal complications of single-agent low-dose methotrexate used in gestational trophoblastic diseases: first reported case of methotrexate-induced peritonitis.

  British journal of cancer 19991101

• Carboxypeptidase G2 rescue in a 79 year-old patient with cranial lymphoma after high-dose methotrexate induced acute renal failure.

  Leukemia & lymphoma 19991101

• Antifungal activities of antineoplastic agents: Saccharomyces cerevisiae as a model system to study drug action.

  Clinical microbiology reviews 19991001

• Immunohistochemical and functional characterization of pH-dependent intestinal absorption of weak organic acids by the monocarboxylic acid transporter MCT1.

  The Journal of pharmacy and pharmacology 19991001

• [Fatal bone marrow aplasia after the 1st injection of methotrexate in a woman with Crohn's disease].

  Gastroenterologie clinique et biologique 19991001

• Intrathecal methotrexate-induced megaloblastic anemia in patients with acute leukemia.

  Archives of pathology & laboratory medicine 19990901

• Angio-neurotic oedema associated with methotrexate treatment in rheumatoid arthritis.

  Rheumatology (Oxford, England) 19990901

• Anterior lumbosacral radiculopathy after intrathecal methotrexate treatment.

  Pediatric neurology 19990801

• Ganciclovir-induced encephalopathy in a bone marrow transplant recipient.

  Bone marrow transplantation 19990801

• Developmental delay in fetal aminopterin/methotrexate syndrome.

  Teratology 19990701

• Toxic epidermal necrolysis and graft vs. host disease: a clinical spectrum but a diagnostic dilemma.

  Clinical and experimental dermatology 19990701

• Molecular cloning and characterization of a new multispecific organic anion transporter from rat brain.

  The Journal of biological chemistry 19990507

• Low-dose oral pulse methotrexate as monotherapy in elderly patients with bullous pemphigoid.

  Journal of the American Academy of Dermatology 19990501

• [Polymyositis induced by tiopronine].

  Presse medicale (Paris, France : 1983) 19990501

• Porphyria cutanea tarda affecting a rheumatoid arthritis patient treated with methotrexate: association or coincidence?

  Rheumatology (Oxford, England) 19990501

• Management of separation pain after single-dose methotrexate therapy for ectopic pregnancy.

  Obstetrics and gynecology 19990401

• Inhibitory effects of combinations of HER-2/neu antibody and chemotherapeutic agents used for treatment of human breast cancers.

  Oncogene 19990401

• Combination therapy in early rheumatoid arthritis: a randomised, controlled, double blind 52 week clinical trial of sulphasalazine and methotrexate compared with the single components.

  Annals of the rheumatic diseases 19990401

• Subacute encephalopathy after combination chemotherapy including moderate-dose methotrexate in a patient with gastric cancer.

  Anti-cancer drugs 19990301

• Leukoencephalopathy complicating an Ommaya reservoir and chemotherapy.

  Neuroradiology 19990201

• Prospective evaluation of high-dose ifosfamide-related nephrotoxicity in young adult patients with recurrent osteosarcoma previously treated with cisplatin, methotrexate and standard-dose ifosfamide.

  Anti-cancer drugs 19990101

• Delayed methotrexate clearance in a patient with sickle cell anemia and osteosarcoma.

  Journal of pediatric hematology/oncology 19990101

• Acute dysarthria induced by low dose methotrexate therapy in a patient with erythrodermic cutaneous T-cell lymphoma: an unusual manifestation of neurotoxicity.

  Clinical and experimental dermatology 19990101

• Toxicity profile of methotrexate in rheumatoid arthritis. A preliminary survey.

  Advances in experimental medicine and biology 19990101

• Nonmetastatic osteosarcoma of the extremity: results of a neoadjuvant chemotherapy protocol (IOR/OS-3) with high-dose methotrexate, intraarterial or intravenous cisplatin, doxorubicin, and salvage chemotherapy based on histologic tumor response.

  Tumori 19990101

• Transient tetraparesis after intrathecal and high-dose systemic methotrexate.

  Annals of hematology 19981101

• Phase III study comparing methotrexate and tacrolimus (prograf, FK506) with methotrexate and cyclosporine for graft-versus-host disease prophylaxis after HLA-identical sibling bone marrow transplantation.

  Blood 19981001

• Long-term nephrotoxicity of cisplatin, ifosfamide, and methotrexate in osteosarcoma.

  Pediatric nephrology (Berlin, Germany) 19980901

• Transient encephalopathy following high-dose methotrexate treatment in childhood acute lymphoblastic leukemia.

  Leukemia 19980801

• Synchronous radiochemotherapy in unfavorable brain tumors of children and young adults.

  Journal of neuro-oncology 19980801

• Acute neurotoxicity in children with B-precursor acute lymphoid leukemia: an association with intermediate-dose intravenous methotrexate and intrathecal triple therapy--a Pediatric Oncology Group study.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 19980501

• Two different drug-induced pulmonary complications in a patient suffering from rheumatoid arthritis.

  British journal of rheumatology 19980501

• Synthesis and biological activities of tricyclic conformationally restricted tetrahydropyrido annulated furo[2,3-d]pyrimidines as inhibitors of dihydrofolate reductases.

  Journal of medicinal chemistry 19980423

• Increased activity of a novel low pH folate transporter associated with lipophilic antifolate resistance in chinese hamster ovary cells.

  The Journal of biological chemistry 19980403

• Demyelination and single-carbon transfer pathway metabolites during the treatment of acute lymphoblastic leukemia: CSF studies.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 19980401

• Successful rescue in a patient with high dose methotrexate-induced nephrotoxicity and acute renal failure.

  Leukemia & lymphoma 19980301

• Pure methotrexate encephalopathy presenting with seizures: CT and MRI features.

  Pediatric radiology 19980201

• Methotrexate induced pericarditis and pericardial effusion in psoriatic patient.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 19980201

• Adult and two children with fetal methotrexate syndrome.

  Teratology 19980201

• Leukocytoclastic vasculitis induced by low-dose methotrexate: in vitro evidence for an immunologic mechanism.

  Journal of the European Academy of Dermatology and Venereology : JEADV 19980101

• Multiple folate enzyme inhibition: mechanism of a novel pyrrolopyrimidine-based antifolate LY231514 (MTA).

  Advances in enzyme regulation 19980101

• Potential salvage therapy for inadvertent intrathecal administration of vincristine.

  British journal of haematology 19971101

• Cutaneous necrotizing vasculitis after low dose methotrexate therapy for rheumatoid arthritis: a possible manifestation of methotrexate hypersensitivity.

  Clinical rheumatology 19971101

• Phase I trial of paclitaxel, carboplatin, and methotrexate with granulocyte colony-stimulating factor and leucovorin in advanced transitional cell carcinoma.

  Seminars in oncology 19971001

• Feasibility of adjuvant chemotherapy for breast cancer patients.

  Japanese journal of clinical oncology 19971001

• Assessment of brain perfusion by 99mTc-HMPAO SPECT in akinetic mutism due to high-dose intravenous methotrexate therapy.

  Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 19971001

• Folate and antifolate pharmacology.

  Seminars in oncology 19971001

• Nonclassical 2,4-diamino-5-aryl-6-ethylpyrimidine antifolates: activity as inhibitors of dihydrofolate reductase from Pneumocystis carinii and Toxoplasma gondii and as antitumor agents.

  Journal of medicinal chemistry 19970912

• Preliminary results. UFT/methotrexate/leucovorin for breast Ca patients in progression after HDCT/PBPC support.

  Oncology (Williston Park, N.Y.) 19970901

• Piperacillin-induced seizures.

  Clinical pediatrics 19970801

• Continuous plasma resin perfusion for detoxification of methotrexate.

  European journal of pediatrics 19970701

• Carboxypeptidase-G2, thymidine, and leucovorin rescue in cancer patients with methotrexate-induced renal dysfunction.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 19970501

• Long-term follow-up of 453 rheumatoid arthritis patients treated with methotrexate: an open, retrospective, observational study.

  British journal of rheumatology 19970501

• Intrathecal methotrexate overdose.

  Acta paediatrica (Oslo, Norway : 1992) 19970401

• Severe central nervous adverse effect of intrathecal chemotherapy in a 16-yr-old patient with Burkitt's type lymphoma.

  European journal of haematology 19970401

• The outcome of unrelated donor bone marrow transplantation in patients with hematologic malignancies using tacrolimus (FK506) and low dose methotrexate for graft-versus-host disease prophylaxis.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 19970401

• Effect of N9-methylation and bridge atom variation on the activity of 5-substituted 2,4-diaminopyrrolo[2,3-d]pyrimidines against dihydrofolate reductases from Pneumocystis carinii and Toxoplasma gondii.

  Journal of medicinal chemistry 19970328

• [High-dose methotrexate and cerebral neurotoxicity. Apropos of a case of arachnoiditis].

  Presse medicale (Paris, France : 1983) 19970301

• Myelodysplastic syndrome following successful therapy of acute promyelocytic leukemia.

  Leukemia 19970101

• Methotrexate related cutaneous vasculitis.

  Clinical rheumatology 19970101

• Tacrolimus and minidose methotrexate for prevention of acute graft-versus-host disease after matched unrelated donor marrow transplantation.

  Blood 19961201

• Liver cirrhosis due to methotrexate in a patient with rheumatoid arthritis.

  The Netherlands journal of medicine 19961201

• [Disseminated pneumoperitoneum during the therapy of lymphoma with methotrexate and cytosine arabinoside].

  Deutsche medizinische Wochenschrift (1946) 19961018

• Increased thromboembolic complications with concurrent tamoxifen and chemotherapy in a randomized trial of adjuvant therapy for women with breast cancer. National Cancer Institute of Canada Clinical Trials Group Breast Cancer Site Group.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 19961001

• Methotrexate hepatotoxicity in psoriatics: report of 104 patients from Nova Scotia, with analysis of risks from obesity, diabetes and alcohol consumption during long term follow-up.

  Canadian journal of gastroenterology = Journal canadien de gastroenterologie 19961001

• Intrathecal leucovorin after intrathecal methotrexate overdose.

  Journal of pediatric hematology/oncology 19960801

• Low dose methotrexate, bleomycin, doxorubicin, cyclophosphamide, vincristine, and dexamethasone with zalcitabine in patients with acquired immunodeficiency syndrome-related lymphoma. Effect on human immunodeficiency virus and serum interleukin-6 levels over time.

  Cancer 19960801

• 2',3'-Didehydro-3'-deoxythymidine: regulation of its metabolic activation by modulators of thymidine-5'-triphosphate biosynthesis.

  Molecular pharmacology 19960701

• Hepatic dysfunction following busulfan and cyclophosphamide myeloablation: a retrospective, multicenter analysis.

  Bone marrow transplantation 19960701

• [Paraplegia following intrathecal chemotherapy].

  Schweizerische medizinische Wochenschrift 19960622

• Acute febrile toxic reaction in patients with refractory rheumatoid arthritis who are receiving combined therapy with methotrexate and azathioprine.

  Arthritis and rheumatism 19960601

• [Untoward effects of low dose methotrexate therapy in rheumatoid arthritis].

  Ryumachi. [Rheumatism] 19960601

• Late cardiotoxicity after treatment for a malignant bone tumor.

  Medical and pediatric oncology 19960401

• Magnetic resonance imaging and neurological evaluation after treatment with high-dose methotrexate for acute lymphocytic leukaemia in young children.

  Acta paediatrica (Oslo, Norway : 1992) 19960401

• 2,4-diamino-5-deaza-6-substituted pyrido[2,3-d]pyrimidine antifolates as potent and selective nonclassical inhibitors of dihydrofolate reductases.

  Journal of medicinal chemistry 19960329

• Severe atypical neuropathy associated with administration of hematopoietic colony-stimulating factors and vincristine.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 19960301

• Ventriculolumbar perfusion chemotherapy with methotrexate and cytosine arabinoside for meningeal carcinomatosis: a pilot study in 13 patients.

  Surgical neurology 19960301

• Effects on fibrogenesis markers of rheumatoid arthritis therapy with methotrexate.

  The Journal of rheumatology 19960301

• High-affinity inhibitors of dihydrofolate reductase: antimicrobial and anticancer activities of 7,8-dialkyl-1,3-diaminopyrrolo[3,2-f]quinazolines with small molecular size.

  Journal of medicinal chemistry 19960216

• Steroid-free chemotherapy decreases the risk of hepatitis flare-up in hepatitis B virus carriers with non-Hodgkin's lymphoma.

  Blood 19960201

• Atypical MRI findings in treatment-related leukoencephalopathy: case report.

  Neuroradiology 19960201

• Anticytomegaloviral activity of methotrexate associated with preferential accumulation of drug by cytomegalovirus-infected cells.

  Antimicrobial agents and chemotherapy 19960201

• Increased matrix proteins, collagen and transforming growth factor are early markers of hepatotoxicity in patients on long-term methotrexate therapy.

  Journal of toxicology. Clinical toxicology 19960101

• Effect of some anticancer drugs and combined chemotherapy on renal toxicity.

  Biological signals 19960101

• [Radiological case of the month. Leukoencephalopathy caused by methotrexate in a child treated for acute lymphoblastic leukemia].

  Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 19960101

• Methotrexate-induced liver cirrhosis. Clinical, histological and serological studies--a further 10-year follow-up.

  Dermatology (Basel, Switzerland) 19960101

• Intelligence quotient in childhood acute lymphoblastic leukemia after prophylactic treatment in central nervous system with 18 Gy cranial irradiation and intrathecal methotrexate.

  Zhonghua Minguo xiao er ke yi xue hui za zhi [Journal]. Zhonghua Minguo xiao er ke yi xue hui 19960101

• Treatment-related disseminated necrotizing leukoencephalopathy with characteristic contrast enhancement of the white matter.

  Radiation medicine 19960101

• New drug developments for opportunistic infections in immunosuppressed patients: Pneumocystis carinii.

  Journal of medicinal chemistry 19951124

• Microangiopathy following allogeneic marrow transplantation. Association with cyclosporine and methylprednisolone for graft-versus-host disease prophylaxis.

  Transplantation 19951115

• Evaluation of potent inhibitors of dihydrofolate reductase in a culture model for growth of Pneumocystis carinii.

  Antimicrobial agents and chemotherapy 19951101

• Abnormalities of serum type III procollagen aminoterminal peptide in methotrexate-treated psoriatic patients with normal liver histology do not correlate with hepatic ultrastructural changes.

  The British journal of dermatology 19951001

• Methotrexate-linked ventricular arrhythmias.

  Acta dermato-venereologica 19950901

• [Pneumocystis carinii pneumonia associated with low dose methotrexate treatment for malignant rheumatoid arthritis].

  Ryumachi. [Rheumatism] 19950801

• Carboxypeptidase-G2 rescue in a patient with high dose methotrexate-induced nephrotoxicity.

  Cancer 19950801

• End-stage liver disease developing with the use of methotrexate in heterozygous alpha 1-antitrypsin deficiency.

  Arthritis and rheumatism 19950701

• Novel 2,4-diamino-5-substituted-pyrrolo[2,3-d]pyrimidines as classical and nonclassical antifolate inhibitors of dihydrofolate reductases.

  Journal of medicinal chemistry 19950609

• Malignant germ cell tumors in men infected with the human immunodeficiency virus: natural history and results of therapy.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 19950601

• FK506 treatment of graft-versus-host disease developing or exacerbating during prophylaxis and therapy with cyclosporin and/or other immunosuppressants. Japanese FK506 BMT Study Group.

  Bone marrow transplantation 19950601

• Ifosfamide-induced Fanconi syndrome.

  The Annals of pharmacotherapy 19950601

• [Ifosfamide-induced hemorrhagic cystitis and its prevention by mesna].

  Gan to kagaku ryoho. Cancer & chemotherapy 19950601

• Treatment of dermatomyositis with methotrexate.

  Journal of the American Academy of Dermatology 19950501

• Methotrexate-induced pericarditis and pericardial effusion; first reported case.

  Postgraduate medical journal 19950401

• Aminophylline for methotrexate-induced neurotoxicity.

  Lancet (London, England) 19950304

• 2,4-Diamino-5-substituted-quinazolines as inhibitors of a human dihydrofolate reductase with a site-directed mutation at position 22 and of the dihydrofolate reductases from Pneumocystis carinii and Toxoplasma gondii.

  Journal of medicinal chemistry 19950303

• The cost-effectiveness of liver biopsy in rheumatoid arthritis patients treated with methotrexate.

  Arthritis and rheumatism 19950301

• Advanced diffuse non-Hodgkin's lymphoma. Analysis of prognostic factors by the international index and by lactic dehydrogenase in an intergroup study.

  Cancer 19950201

• Guanosine triphosphate cyclohydrolase I regulates nitric oxide synthesis in renal proximal tubules.

  Journal of the American Society of Nephrology : JASN 19950201

• [Delayed clearance of methotrexate in a patient with malignant lymphoma who developed renal failure].

  Gan to kagaku ryoho. Cancer & chemotherapy 19950201

• Methotrexate-induced leukoencephalopathy. A case report.

  The Turkish journal of pediatrics 19950101

• Acute sensorineural hearing loss following intravenous ketoralac administration.

  The Journal of emergency medicine 19950101

• Arterial thrombosis after chemotherapy with cisplatin, vinblastine and methotrexate.

  The British journal of clinical practice 19950101

• Urinary N-acetyl-beta-D-glucosaminidase activity in leukaemic children during high-dose methotrexate therapy.

  Haematologia 19950101

• Possible cardiac side effects of granisetron, an antiemetic agent, in patients with bone and soft-tissue sarcomas receiving cytotoxic chemotherapy.

  Cancer chemotherapy and pharmacology 19950101

• A randomized, double-blind, cross-over study comparing a levosulpiride-based and a metoclopramide-based combination in the prevention of ProMECE-CytaBOM-induced emesis.

  Haematologica 19950101

• A case of methotrexate-induced acute renal failure successfully treated with plasma perfusion and sequential hemodialysis.

  Nephron 19950101

• [Cutaneous pseudolymphoma during treatment of rheumatoid polyarthritis with low-dose methotrexate].

  Annales de dermatologie et de venereologie 19950101

• [Methotrexate pneumonitis arising during the treatment of non-Hodgkin's lymphomas with the m-BACOD protocol].

  Bulletin du cancer 19950101

• Visual hallucinations following treatment with vincristine.

  Clinical and laboratory haematology 19941201

• The value of a baseline liver biopsy prior to methotrexate treatment.

  The British journal of dermatology 19941201

• Neuropsychologic effects of cranial irradiation, intrathecal methotrexate, and systemic methotrexate in childhood cancer.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 19941201

• Methotrexate in the treatment of psoriasis at the National Skin Centre, Singapore.

  Annals of the Academy of Medicine, Singapore 19941101

• [A heart transplant in a patient with doxorubicin-induced myocardiopathy as a complication of the treatment of a lymphoma].

  Revista espanola de cardiologia 19941101

• Cirrhosis in patients with rheumatoid arthritis receiving low dose methotrexate.

  British journal of rheumatology 19941001

• Vinorelbine is an active antiproliferative agent in pretreated advanced breast cancer patients: a phase II study.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 19941001

• Expression of the human multidrug resistance gene (MDR1) and prognostic correlation in human osteogenic sarcoma.

  The Tokai journal of experimental and clinical medicine 19940901

• Comparison of two schedules of intermediate-dose methotrexate and cytarabine consolidation therapy for childhood B-precursor cell acute lymphoblastic leukemia: a Pediatric Oncology Group study.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 19940901

• The clinical potential of ademetionine (S-adenosylmethionine) in neurological disorders.

  Drugs 19940801

• Transient neurological disturbances induced by the chemotherapy of high-dose methotrexate for osteogenic sarcoma.

  Anti-cancer drugs 19940801

• Acute diffuse muscular pain following initiation of methotrexate therapy.

  Annals of the rheumatic diseases 19940701

• Underrecognized postdosing reactions to methotrexate in patients with rheumatoid arthritis.

  The Journal of rheumatology 19940701

• Bladder cancer in patients on low-dose methotrexate and corticosteroids.

  Lancet (London, England) 19940514

• Accelerated nodulosis, pleural effusion, and pericardial tamponade during methotrexate therapy.

  The Journal of rheumatology 19940501

• Classical and nonclassical furo[2,3-d]pyrimidines as novel antifolates: synthesis and biological activities.

  Journal of medicinal chemistry 19940415

• [Severe bone marrow aplasia associated with cloxacillin treatment].

  Sangre 19940401

• [Extra-articular manifestations of rheumatoid arthritis at the time of basic methotrexate treatment: apropos of a case of nodulosis with pericarditis].

  Revue medicale de la Suisse romande 19940401

• Infection rate and use of antibiotics in patients with rheumatoid arthritis treated with methotrexate.

  Annals of the rheumatic diseases 19940401

• Methotrexate exposure prior to and during pregnancy.

  Teratology 19940201

• [Effects of drugs on the liver. A review illustrated with 3 clinical cases].

  Ugeskrift for laeger 19940110

• Postoperative chemotherapy increases the disease-free survival rate in primary gastric lymphomas stage IE and IIE.

  European journal of cancer (Oxford, England : 1990) 19940101

• Comparable prognostic factors and survival in elderly patients with aggressive non-Hodgkin's lymphoma treated with standard-dose adriamycin-based regimens.

  Annals of oncology : official journal of the European Society for Medical Oncology 19940101

• A phase III comparison of CHOP vs. m-BACOD vs. ProMACE-CytaBOM vs. MACOP-B in patients with intermediate- or high-grade non-Hodgkin's lymphoma: results of SWOG-8516 (Intergroup 0067), the National High-Priority Lymphoma Study.

  Annals of oncology : official journal of the European Society for Medical Oncology 19940101

• Acute ascending myelitis and encephalopathy after intrathecal cytosine arabinoside and methotrexate in an adolescent boy with acute lymphoblastic leukemia.

  Brain & development 19940101

• Concurrent acute megaloblastic anaemia and pneumonitis: a severe side-effect of low-dose methotrexate therapy during rheumatoid arthritis.

  Clinical rheumatology 19931201

• Changes in cell and protein content of cerebrospinal fluid in children with acute lymphoblastic leukaemia after allogeneic bone marrow transplantation.

  Bone marrow transplantation 19931201

• The effect of long-term methotrexate therapy on hepatic fibrosis in rheumatoid arthritis.

  Arthritis and rheumatism 19931201

• Fulminant hepatic failure after methotrexate and PUVA therapy for psoriasis.

  Journal of clinical gastroenterology 19931201

• Evaluation of kidney and liver subacute toxicity of antitumor agents using serum biochemical parameters in rats.

  Biochemistry and molecular biology international 19931101

• Comparison of methods for identifying early methotrexate-induced hepatotoxicity in patients with rheumatoid arthritis.

  Journal of nuclear medicine : official publication, Society of Nuclear Medicine 19931101

• Ultraviolet recall associated with etoposide and cyclophosphamide therapy.

  Clinical and experimental dermatology 19930901

• Identification of highly potent and selective inhibitors of Toxoplasma gondii dihydrofolate reductase.

  Antimicrobial agents and chemotherapy 19930901

• Severe megaloblastic anemia in a patient receiving low-dose methotrexate for psoriasis.

  Journal of the American Academy of Dermatology 19930901

• Methotrexate-induced neurotoxicity: appearance on indium-111-white blood cells, gallium-67-citrate and thallium-201-chloride scintigraphy.

  Journal of nuclear medicine : official publication, Society of Nuclear Medicine 19930801

• Renal effects of low dose methotrexate in rheumatoid arthritis.

  The Journal of rheumatology 19930701

• Primary chemotherapy for obstructive jaundice caused by intermediate-grade non-Hodgkin lymphoma.

  Cancer 19930501

• Porphyria cutanea tarda associated with methotrexate therapy.

  British journal of rheumatology 19930501

• Fatal cardiac nodules in a patient with rheumatoid arthritis treated with low dose methotrexate.

  The Journal of rheumatology 19930501

• Comparison of a standard regimen (CHOP) with three intensive chemotherapy regimens for advanced non-Hodgkin's lymphoma.

  The New England journal of medicine 19930408

• Methotrexate induced brain necrosis and severe leukoencephalopathy due to disconnection of an Ommaya device.

  Journal of neuro-oncology 19930301

• Determinants of serious liver disease among patients receiving low-dose methotrexate for rheumatoid arthritis.

  Arthritis and rheumatism 19930301

• Liver cirrhosis in rheumatoid arthritis patients treated with long-term methotrexate.

  Veterinary and human toxicology 19930201

• Oculomotor nerve palsy associated with vincristine treatment.

  Acta haematologica 19930101

• Liver fibrosis quantified by image analysis in methotrexate-treated patients with psoriasis.

  Journal of the American Academy of Dermatology 19930101

• Treatment of osteosarcoma: experience of the Cooperative Osteosarcoma Study Group (COSS).

  Cancer treatment and research 19930101

• Cerebral arterial disturbances in a transient encephalopathy induced by methotrexate.

  Medical oncology and tumor pharmacotherapy 19930101

• Long-term cerebral effects of CNS chemotherapy in children with acute lymphoblastic leukemia.

  Pediatric hematology and oncology 19930101

• A toxic interaction between mitomycin C and tamoxifen causing the haemolytic uraemic syndrome.

  European journal of cancer (Oxford, England : 1990) 19930101

• Proteinuria due to suboptimal hydration with high-dose methotrexate therapy.

  Cancer chemotherapy and pharmacology 19930101

• Pharmacokinetics and in vitro studies of l-leucovorin. Comparison with the d and d,l-leucovorin.

  Annals of oncology : official journal of the European Society for Medical Oncology 19930101

• Long-term effects of vincristine on the peripheral nervous system.

  Journal of neuro-oncology 19930101

• Myocardial ischemia after treatment with methotrexate, etoposide and cisplatin.

  Urologia internationalis 19930101

• Acute arterial thrombosis after escalated-dose methotrexate, vinblastine, doxorubicin, and cisplatin chemotherapy with recombinant granulocyte colony-stimulating factor. A possible new recombinant granulocyte colony-stimulating factor toxicity.

  Cancer 19921201

• Comparison of a second-generation combination chemotherapeutic regimen (m-BACOD) with a standard regimen (CHOP) for advanced diffuse non-Hodgkin's lymphoma.

  The New England journal of medicine 19921105

• The BFM-protocol for HIV-negative Burkitt's lymphomas and L3 ALL in adult patients: a high chance for cure.

  Annals of hematology 19921101

• [Methotrexate-induced skin detachment].

  Presse medicale (Paris, France : 1983) 19921024

• A pilot study on the influence of a corticotropin (4-9) analogue on Vinca alkaloid-induced neuropathy.

  Archives of neurology 19921001

• Three cases of malignant neoplasm, pneumonitis, and pancytopenia during treatment with low-dose methotrexate.

  The Clinical investigator 19921001

• Nuclear magnetic resonance abnormalities of the cerebral white matter in children with acute lymphoblastic leukemia and malignant lymphoma during and after central nervous system prophylactic treatment with intrathecal methotrexate.

  Cancer 19921001

• Methotrexate hepatotoxicity in psoriatic patients submitted to long-term therapy.

  Acta dermato-venereologica 19920901

• [Transient subacute encephalopathy induced by high-dose methotrexate treatment in children with acute lymphoblastic leukemia and malignant lymphoma].

  Gan to kagaku ryoho. Cancer & chemotherapy 19920901

• Orofacial complications of chemotherapy for breast cancer.

  Oral surgery, oral medicine, and oral pathology 19920801

• Treatment of recurrent head and neck cancer with cisplatin and 5-fluorouracil vs. the same plus bleomycin and methotrexate.

  The Laryngoscope 19920801

• Dynamic hepatic scintigraphy in the screening of psoriatic patients for methotrexate-induced hepatotoxicity.

  The British journal of dermatology 19920801

• [Effective treatment of liver metastasis and peritoneal dissemination of gastric cancer using intra-arterial therapy--a case report].

  Gan to kagaku ryoho. Cancer & chemotherapy 19920801

• [Burgdorf's reaction (painful acral erythema) in patients with acute lymphoblastic leukemia following medium-dose methotrexate therapy].

  Wiadomosci lekarskie (Warsaw, Poland : 1960) 19920601

• Marked increase in veno-occlusive disease of the liver associated with methotrexate use for graft-versus-host disease prophylaxis in patients receiving busulfan/cyclophosphamide.

  Blood 19920515

• [Neurologic complications during chemotherapy of children with acute lymphoid leukemia].

  Orvosi hetilap 19920503

• The relationship of sex and treatment modality to neuropsychologic outcome in childhood acute lymphoblastic leukemia.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 19920501

• Biochemical and biological studies on 2-desamino-2-methylaminopterin, an antifolate the polyglutamates of which are more potent than the monoglutamate against three key enzymes of folate metabolism.

  Cancer research 19920415

• Methotrexate treatment of severe asthma in children.

  Pediatrics 19920401

• Cytotoxic analog of somatostatin containing methotrexate inhibits growth of MIA PaCa-2 human pancreatic cancer xenografts in nude mice.

  Cancer letters 19920315

• [Nodular efflorescence and cutaneous vasculitis in rheumatoid arthritis treated with methotrexate].

  Presse medicale (Paris, France : 1983) 19920307

• Pyrazole-related nucleosides. Synthesis and antiviral/antitumor activity of some substituted pyrazole and pyrazolo[4,3-d]-1,2,3-triazin-4-one nucleosides.

  Journal of medicinal chemistry 19920306

• Akinetic mutism in bilateral necrotizing leucoencephalopathy after radiation and chemotherapy: electrophysiological and autopsy findings.

  Journal of neurology 19920301

• Low dose methotrexate treatment in adult Still's disease.

  The Journal of rheumatology 19920301

• Toxicity and side-effects of combination chemohormonal therapy of advanced breast cancer.

  Journal of the Indian Medical Association 19920201

• Clinical liver disease in patients with rheumatoid arthritis taking methotrexate.

  The Journal of rheumatology 19920201

• Long-term prospective study of methotrexate in the treatment of rheumatoid arthritis. 84-month update.

  Arthritis and rheumatism 19920201

• Methotrexate increases valproic acid-induced developmental toxicity, in particular neural tube defects in mice.

  Teratogenesis, carcinogenesis, and mutagenesis 19920101

• Transient encephalopathy following a single exposure of high-dose methotrexate in a child with acute lymphoblastic leukemia.

  Pediatric hematology and oncology 19920101

• Substitutive therapy in a case of methotrexate neurotoxicity.

  European journal of cancer (Oxford, England : 1990) 19920101

• Vitamin neurotoxicity.

  Molecular neurobiology 19920101

• Long-term neuropsychologic sequelae of childhood leukemia: comparison of two CNS prophylactic regimens.

  International journal of radiation oncology, biology, physics 19920101

• Visual field defects during low-dose methotrexate therapy.

  Documenta ophthalmologica. Advances in ophthalmology 19920101

• The effects of a salicylate, ibuprofen, and naproxen on the disposition of methotrexate in patients with rheumatoid arthritis.

  European journal of clinical pharmacology 19920101

• Behavioral effects of corticosteroids in children with acute lymphoblastic leukemia.

  Medical and pediatric oncology 19920101

• [Early neurotoxicity of high-dose of methotrexate and tetrahydrobiopterin deficiency].

  Archives francaises de pediatrie 19911201

• Adjuvant chemotherapy with doxorubicin plus cyclophosphamide, methotrexate, and fluorouracil in the treatment of resectable breast cancer with more than three positive axillary nodes.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 19911201

• [Clinical evaluation of severe toxicity in two patients with acute lymphoblastic leukemia receiving outpatient methotrexate therapy].

  [Rinsho ketsueki] The Japanese journal of clinical hematology 19911101

• Neurologic complications in allogeneic bone marrow transplant patients receiving cyclosporin.

  Bone marrow transplantation 19911101

• Stroke-like syndrome, mineralizing microangiopathy, and neuroaxonal dystrophy following intrathecal methotrexate therapy.

  Neurology 19911101

• Ornithine decarboxylase induction in mouse kidney as indicator of renal damage. Differential nephrotoxic effect of anticancer antifolate drugs.

  Cancer letters 19910901

• Drug-related pulmonary toxicity in non-Hodgkin's lymphoma. Comparative results with three different treatment regimens.

  Cancer 19910815

• Acute hepatotoxicity after high-dose methotrexate administration to rats.

  Pharmacology & toxicology 19910801

• Low dose MTX and NSAID induced 'mild' renal insufficiency and severe neutropenia.

  The Journal of rheumatology 19910801

• Clinical use of thymidine as a rescue agent from methotrexate toxicity.

  Investigational new drugs 19910801

• Low-dose chemotherapy with central nervous system prophylaxis and zidovudine maintenance in AIDS-related lymphoma. A prospective multi-institutional trial.

  JAMA 19910703

• Serum aminoterminal propeptide of type III procollagen in psoriasis and psoriatic arthritis: relation to liver fibrosis and arthritis.

  Journal of the American Academy of Dermatology 19910701

• The efficacy and toxicity of a constant low dose of methotrexate as a treatment for intractable rheumatoid arthritis: an open prospective study.

  The Journal of rheumatology 19910701

• Pneumocystis carinii dihydrofolate reductase used to screen potential antipneumocystis drugs.

  Antimicrobial agents and chemotherapy 19910701

• Methotrexate and histologic hepatic abnormalities: a meta-analysis.

  The American journal of medicine 19910601

• Hemiparesis and ischemic changes of the white matter after intrathecal therapy for children with acute lymphocytic leukemia.

  Cancer 19910415

• Low-dose methotrexate and cholangiocarcinoma of the common hepatic duct.

  Arthritis and rheumatism 19910401

• Brain lesions following combined treatment with methotrexate and craniospinal irradiation.

  Journal of neuro-oncology 19910401

• [Hepatocellular carcinoma in a patient with psoriasis and methotrexate-induced cirrhosis].

  Gastroenterologie clinique et biologique 19910101

• m-BACOD chemotherapy for intermediate- and high-grade non-Hodgkin's lymphoma.

  Cancer chemotherapy and pharmacology 19910101

• The role of maintenance therapy in the treatment of large-cell non-Hodgkin's lymphoma.

  Acta oncologica (Stockholm, Sweden) 19910101

• Transient cerebral dysfunction after treatment with moderately high-dose methotrexate.

  Annals of oncology : official journal of the European Society for Medical Oncology 19910101

• Acute reversible neurotoxicity after intrathecal low-dose methotrexate.

  European journal of cancer (Oxford, England : 1990) 19910101

• Inhibition of Pneumocystis dihydrofolate reductase by analogs of pyrimethamine, methotrexate and trimetrexate.

  The Journal of protozoology 19910101

• Acute reversible neurological deficit following intrathecal chemotherapy.

  Cancer chemotherapy and pharmacology 19910101

• Acute fatal myeloencephalopathy after combined intrathecal chemotherapy in a child with acute lymphoblastic leukemia.

  Medical and pediatric oncology 19910101

• High dose intravenous methotrexate and reversible focal neurological deficit.

  British journal of haematology 19901201

• [Fulminant hepatic failure induced by intermediate dose methotrexate in a case of non-Hodgkin's lymphoma].

  [Rinsho ketsueki] The Japanese journal of clinical hematology 19901101

• Incidence of neuropathy in 395 patients with ovarian cancer treated with or without cisplatin.

  Cancer 19901015

• Severe polyneuropathy and motor loss after intrathecal thiotepa combination chemotherapy: description of two cases.

  Anti-cancer drugs 19901001

• Methotrexate hepatotoxicity and the premature reporting of Mark Twain's death: both greatly exaggerated.

  Hepatology (Baltimore, Md.) 19901001

• Liver histology in patients receiving low dose pulse methotrexate for the treatment of rheumatoid arthritis.

  Annals of the rheumatic diseases 19900801

• Hepatitis with bridging fibrosis and reversible hepatic insufficiency in a woman with rheumatoid arthritis taking methotrexate.

  Arthritis and rheumatism 19900701

• [Acute coronary thrombosis and myocardial ischemia following chemotherapy of Hodgkin's disease].

  Onkologie 19900601

• Hepatic fibrosis with the use of methotrexate for juvenile rheumatoid arthritis.

  The Journal of rheumatology 19900601

• Dose response relationship of methotrexate in combination with cisplatin in murine bladder cancer.

  Urology 19900301

• Early blindness and coma during intrathecal chemotherapy for meningeal carcinomatosis.

  Cancer 19900201

• 5-Fluorouracil cardiotoxicity.

  European journal of gynaecological oncology 19900101

• Methotrexate-induced leukoencephalopathy is treatable with high-dose folinic acid: a case report and analysis of the literature.

  Pediatric hematology and oncology 19900101

• An adult case of acute lymphoblastic leukemia with necrotizing leukoencephalopathy.

  Japanese journal of medicine 19900101

• Serum type III procollagen peptide, dynamic liver function tests and hepatic fibrosis in psoriatic patients receiving methotrexate.

  The British journal of dermatology 19900101

• Sudden neurologic death after intrathecal methotrexate.

  Medical and pediatric oncology 19900101

• [Enhancing factors in the cardiotoxicity of anthracyclines].

  Anales espanoles de pediatria 19900101

• [Neurologic toxicity with low-dose methotrexate treatment].

  La Revue de medecine interne 19900101

• MR findings in methotrexate-induced CNS abnormalities.

  AJR. American journal of roentgenology 19891201

• Impotence in three rheumatoid arthritis patients treated with methotrexate.

  Arthritis and rheumatism 19891001

• Detection of hepatotoxicity associated with methotrexate therapy for psoriasis.

  Archives of dermatology 19890901

• Eruption of nodulosis and vasculitis during methotrexate therapy for rheumatoid arthritis.

  Clinical rheumatology 19890901

• Acute cerebral oedema induced by methotrexate.

  BMJ (Clinical research ed.) 19890819

• Acute, reversible hepatic failure associated with methotrexate treatment of rheumatoid arthritis.

  The Journal of rheumatology 19890801

• Cutaneous vasculitis after intermediate dose of methotrexate (IDMTX).

  British journal of haematology 19890801

• Acute cerebral oedema induced by methotrexate.

  BMJ (Clinical research ed.) 19890708

• Oral low-dose methotrexate (MTX) to be efficient in refractory rheumatoid arthritis and adult-onset Still's disease.

  American journal of kidney diseases : the official journal of the National Kidney Foundation 19890701

• Reversible treatment-related leukoencephalopathy.

  Journal of child neurology 19890701

• Acral erythema secondary to high-dose cytosine arabinoside with pain worsened by cyclosporine infusions.

  Cancer 19890615

• Acute cerebral oedema induced by methotrexate.

  BMJ (Clinical research ed.) 19890513

• Methotrexate neurotoxicity: in vitro studies using cerebellar explants from rats.

  Cancer research 19890501

• Combination chemotherapy for primary small intestinal lymphoma in the Middle East.

  European journal of cancer & clinical oncology 19890501

• The folate antagonist, methotrexate, is a potent inhibitor of murine and human cytomegalovirus in vitro.

  Antiviral research 19890301

• Behavioral side-effects of CNS prophylaxis.

  Journal of the American Academy of Child and Adolescent Psychiatry 19890301

• Mutants of human colon adenocarcinoma, selected for thymidylate synthase deficiency.

  Proceedings of the National Academy of Sciences of the United States of America 19890201

• Liver histology in rheumatoid arthritis patients receiving long-term methotrexate therapy. A prospective study with baseline and sequential biopsy samples.

  Arthritis and rheumatism 19890201

• Salvage of relapsed malignant histiocytosis by autologous bone marrow transplant.

  Bone marrow transplantation 19890101

• MR findings in methotrexate-induced CNS abnormalities.

  AJNR. American journal of neuroradiology 19890101

• Severe renal toxicity due to intermediate-dose methotrexate.

  Cancer chemotherapy and pharmacology 19890101

• Serum aminoterminal propeptide of type III procollagen. A non-invasive test for liver fibrogenesis in methotrexate-treated psoriatics.

  Acta dermato-venereologica 19890101

• Cochleovestibular toxicity related to dichloromethotrexate.

  Cancer investigation 19890101

• Methotrexate-related multifocal axonopathy. Report of an autopsy case.

  Acta neuropathologica 19890101

• The effects of diltiazem on methotrexate-induced nephrotoxicity.

  European journal of clinical pharmacology 19890101

• Experimental study on subacute neurotoxicity of methotrexate in cats.

  Acta neuropathologica 19890101

• Prospective evaluation of chronic cardiotoxicity due to high-dose epirubicin or combination chemotherapy with cyclophosphamide, methotrexate, and 5-fluorouracil.

  Cancer chemotherapy and pharmacology 19890101

• Seizure associated with low-dose naloxone.

  The American journal of emergency medicine 19890101

• Acute renal failure after high-dose methotrexate therapy. Role of hemodialysis and plasma exchange in methotrexate removal.

  Nephron 19890101

• Methotrexate-associated hepatotoxicity: retrospective analysis of 210 patients with rheumatoid arthritis.

  The American journal of medicine 19881201

• Histopathologic findings in the liver of rheumatoid arthritis patients treated with long-term bolus methotrexate.

  Arthritis and rheumatism 19881201

• Aggressive treatment improves survival in adult acute lymphoblastic leukemia.

  European journal of haematology 19881101

• Death from chemotherapy in gestational trophoblastic disease.

  European journal of obstetrics, gynecology, and reproductive biology 19881001

• Acute fever and delayed leukoencephalopathy following low dose intraventricular methotrexate.

  Journal of neurology, neurosurgery, and psychiatry 19881001

• Adjuvant chemotherapy for patients with high-grade soft-tissue sarcomas of the extremity.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 19880901

• Aminoterminal propeptide of type III procollagen in methotrexate-induced liver fibrosis and cirrhosis.

  The British journal of dermatology 19880901

• Accelerated nodulosis and vasculitis during methotrexate therapy for rheumatoid arthritis.

  Arthritis and rheumatism 19880901

• [Increased secretion of vasopressin and edema formation in high dosage methotrexate therapy].

  Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete 19880801

• Methotrexate analogues. 32. Chain extension, alpha-carboxyl deletion, and gamma-carboxyl replacement by sulfonate and phosphonate: effect on enzyme binding and cell-growth inhibition.

  Journal of medicinal chemistry 19880701

• A long-term prospective study of the use of methotrexate in rheumatoid arthritis. Update after a mean of fifty-three months.

  Arthritis and rheumatism 19880501

• Southwest Oncology Group clinical trials for intermediate- and high-grade non-Hodgkin's lymphomas.

  Seminars in hematology 19880401

• Methotrexate leukoencephalopathy mimicking cerebral abscess on CT brain scan.

  Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 19880401

• [Serial spectral EEG analysis in a patient with non-Hodgkin's lymphoma complicated by leukoencephalopathy induced by high-dose methotrexate].

  Gan to kagaku ryoho. Cancer & chemotherapy 19880401

• Methotrexate-induced impairment of taste acuity.

  Clinical and experimental dermatology 19880301

• Sexual dysfunction among patients with arthritis.

  Clinical rheumatology 19880301

• Natural and Chang liver cell cytotoxic studies of methotrexate-treated psoriatic patients with liver cirrhosis.

  Acta dermato-venereologica 19880101

• Primitive neuroectodermal tumor presenting as a delayed sequela to cranial irradiation and intrathecal methotrexate.

  Pediatric neurology 19880101

• Severe vincristine neurotoxicity in a patient with Charcot-Marie-Tooth disease.

  Pediatric hematology and oncology 19880101

• Renal impairment following the combined use of high-dose methotrexate and procarbazine.

  Cancer chemotherapy and pharmacology 19880101

• Hepatocellular carcinoma in a long-term survivor of acute lymphocytic leukemia.

  Cancer 19871115

• Comparison of single agent cisplatin and cisplatin containing combinations in treatment of murine bladder cancer.

  Urology 19871101

• Four-drug sequential regimen in advanced breast cancer.

  Breast cancer research and treatment 19871101

• Encephalomyelitis associated with leukemia in a child.

  Journal of child neurology 19871001

• Chemotherapy for adenocarcinoma of the lung (WHO III): A randomized study of vindesine versus lomustine, cyclophosphamide, and methotrexate versus all four drugs.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 19870801

• [Intrathecal methotrexate--overdosing in pediatric lymphoblastic leukemia].

  Psychiatrie, Neurologie, und medizinische Psychologie 19870601

• Southwest oncology group clinical trials for intermediate- and high-grade non-Hodgkin's lymphomas.

  Seminars in hematology 19870401

• Cerebral dysfunction secondary to high-dose methotrexate.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 19870401

• Activity of antifolates against Pneumocystis carinii dihydrofolate reductase and identification of a potent new agent.

  The Journal of experimental medicine 19870301

• The aminopyrine breath test, an inadequate early indicator of methotrexate-induced liver disease in patients with psoriasis.

  Clinical and investigative medicine. Medecine clinique et experimentale 19870301

• Toxicity of methotrexate in rheumatoid arthritis.

  The Journal of rheumatology 19870201

• Use of charcoal hemoperfusion with sequential hemodialysis to reduce serum methotrexate levels in a patient with acute renal insufficiency.

  The American journal of medicine 19870201

• Methotrexate hepatotoxicity and concentrations of methotrexate and folate in erythrocytes--relation to liver fibrosis and cirrhosis.

  Acta dermato-venereologica 19870101

• Convulsions and intracranial calcifications in a leukemic infant receiving only intrathecal methotrexate as central nervous system prophylaxis.

  Pediatric hematology and oncology 19870101

• [Subclinical leukoencephalopathy caused by methotrexate].

  Neurologia (Barcelona, Spain) 19870101

• Transient acute hepatotoxicity of high-dose methotrexate therapy during childhood.

  NCI monographs : a publication of the National Cancer Institute 19870101

• Reduced cerebral glucose metabolism and increased brain capillary permeability following high-dose methotrexate chemotherapy: a positron emission tomographic study.

  Annals of neurology 19870101

• Hepatotoxicity associated with low-dose, long-term methotrexate treatment of rheumatoid arthritis.

  Scandinavian journal of rheumatology 19870101

• Methotrexate-induced liver cirrhosis. A follow-up.

  Dermatologica 19870101

• Androgen depletion and repletion as a means of potentiating the effect of cytotoxic chemotherapy in advanced prostate cancer.

  Journal of steroid biochemistry 19870101

• Enhancement of methotrexate nephrotoxicity after cisplatin therapy.

  Cancer 19861215

• Transient cerebral dysfunction secondary to high-dose methotrexate.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 19861201

• Acute toxicity of epirubicin.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 19861201

• [Transient cerebral dysfunction induced by VCR, HD-MTX in a child with acute lymphocytic leukemia].

  [Rinsho ketsueki] The Japanese journal of clinical hematology 19861101

• Acute high-dose methotrexate neurotoxicity in the rat.

  Annals of neurology 19861101

• Effects of intraventricular methotrexate on cerebrospinal fluid monoamine metabolites in rhesus monkeys.

  Cancer treatment reports 19861001

• Myelin basic protein in CSF of children receiving intrathecal chemotherapy.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 19861001

• [Renal dipeptidylpeptidase IV excretion in drug-induced kidney changes].

  Zeitschrift fur Urologie und Nephrologie 19861001

• A model of methotrexate encephalopathy: neurotransmitter and pathologic abnormalities.

  Journal of child neurology 19861001

• Leukocytoclastic vasculitis after high-dose methotrexate.

  Annals of internal medicine 19860901

• Acute renal failure due to concomitant action of methotrexate and indomethacin.

  Lancet (London, England) 19860614

• Hepatotoxicity after long-term methotrexate therapy.

  Southern medical journal 19860501

• Exaggerated hypotension by N-formylmethionylleucyl-phenylalanine in indomethacin pretreated rats. Role of toxic oxygen.

  Agents and actions 19860301

• Clinical and pharmacokinetic evidence of a life-threatening interaction between methotrexate and ketoprofen.

  Lancet (London, England) 19860201

• Megaloblastic anaemia and methotrexate treatment.

  The British journal of dermatology 19860201

• Toxicity of low dose methotrexate in rheumatoid arthritis.

  The Journal of rheumatology. Supplement 19851201

• The impact of methotrexate on psycho-organic functioning.

  The British journal of dermatology 19851001

• Transient neurologic disturbances induced by high-dose methotrexate treatment.

  Cancer 19850915

• Enhanced inhibition of thymidylate synthase by methotrexate polyglutamates.

  The Journal of biological chemistry 19850815

• Central nervous system morbidity following an initial isolated central nervous system relapse and its subsequent therapy in childhood acute lymphoblastic leukemia.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 19850501

• Megaloblastic anaemia in psoriatic patients treated with methotrexate.

  The British journal of dermatology 19850501

• High-dose methotrexate-induced neurotoxicity associated with elevation of CSF myelin basic protein.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 19850401

• Remission induction of meningeal leukemia with high-dose intravenous methotrexate.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 19850401

• Incidence of hypertension after marrow transplantation among 112 patients randomized to either cyclosporine or methotrexate as graft-versus-host disease prophylaxis.

  British journal of haematology 19850301

• Acute renal failure and death following sequential intermediate-dose methotrexate and 5-FU: a possible adverse effect due to concomitant indomethacin administration.

  Cancer treatment reports 19850301

• Incidence of neoplasms in patients with rheumatoid arthritis exposed to different treatment regimens.

  The American journal of medicine 19850121

• Hepatotoxicity of prolonged methotrexate therapy for rheumatoid arthritis.

  Cleveland Clinic quarterly 19850101

• Transient encephalopathy after local application of methotrexate.

  Neuroradiology 19850101

• Transient neurologic dysfunction following moderate-dose methotrexate for undifferentiated lymphoma.

  Cancer 19841101

• Randomised trial comparing two combination chemotherapy regimens (Hexa-CAF vs CHAP-5) in advanced ovarian carcinoma.

  Lancet (London, England) 19840915

• Drug testing using a soft agar stem cell assay on patient and xenograft tumor material.

  International journal of radiation oncology, biology, physics 19840901

• Sequential methotrexate and 5-fluorouracil: improved response rate in metastatic colorectal cancer.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 19840601

• Small-vessel vasculitis and methotrexate.

  Annals of internal medicine 19840601

• [Cerebral complications after irradiation and administration of methotrexate in lymphatic leukemia in the computerized tomography picture].

  Ceskoslovenska neurologie a neurochirurgie 19840501

• Transient encephalopathy during the late course of treatment with high-dose methotrexate.

  Cancer 19840501

• Phase II and pharmacokinetic study of high-dose methotrexate in the treatment of advanced gynecologic malignancy. A Southwest Oncology Group Trial.

  Gynecologic oncology 19840501

• [Nephrotoxicity of antitumor chemotherapy].

  Presse medicale (Paris, France : 1983) 19840428

• Methotrexate in the treatment of metastatic and recurrent primary transitional cell carcinoma.

  The Journal of urology 19840301

• [Evaluation of severe side effects of high-dose methotrexate in osteosarcoma].

  Gan to kagaku ryoho. Cancer & chemotherapy 19840201

• Neurological complications of antineoplastic therapy.

  Acta neurologica Scandinavica. Supplementum 19840101

• Evaluation of chemotherapy in a murine model for bladder cancer.

  Oncology 19840101

• A murine model for bladder cancer.

  Progress in clinical and biological research 19840101

• Vascular changes of methotrexate-related disseminated necrotizing leukoencephalopathy.

  Acta neuropathologica 19840101

• Electroencephalographic findings in children treated with cytotoxic agents.

  Neuropsychobiology 19840101

• Paraparesis following intrathecal chemotherapy.

  Neurology 19830801

• Methotrexate-induced immune haemolytic anaemia.

  British journal of haematology 19830801

• Neurologic symptoms associated with parenteral acyclovir treatment after marrow transplantation.

  Annals of internal medicine 19830601

• MTX/5-FU trials in gastrointestinal and other cancers.

  Seminars in oncology 19830601

• Cyclosporin A associated nephrotoxicity in the first 100 days after allogeneic bone marrow transplantation: three distinct syndromes.

  British journal of haematology 19830501

• Assessment of liver function using fasting bile salt concentrations in psoriasis prior to and during methotrexate therapy.

  Clinica chimica acta; international journal of clinical chemistry 19830425

• Acute renal toxicity with combined use of amphotericin B and cyclosporine after marrow transplantation.

  Transplantation 19830301

• Methotrexate-induced renal impairment: clinical studies and rescue from systemic toxicity with high-dose leucovorin and thymidine.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 19830301

• [Porphyria cutanea tarda caused by methotrexate and buthiopurine therapy].

  Zeitschrift fur Hautkrankheiten 19830215

• [Case of disseminated necrotizing leukoencephalopathy following intrathecal methotrexate in acute lymphocytic leukemia].

  Gan no rinsho. Japan journal of cancer clinics 19830201

• Psychological response of patients receiving two drug regimens for lung carcinoma.

  The American journal of psychiatry 19830101

• Toxicity associated with combination chemotherapy for osteosarcoma: a report of the cooperative osteosarcoma study (COSS 80).

  Journal of cancer research and clinical oncology 19830101

• High dose systemic methotrexate-associated acute neurologic dysfunction.

  Medical and pediatric oncology 19830101

• Chemical pleuritis as the cause of acute chest pain following high-dose methotrexate treatment.

  Cancer 19830101

• Complications in methotrexate treatment of psoriasis with particular reference to liver fibrosis.

  The Journal of investigative dermatology 19821001

• Necrotising leucoencephalopathy associated with intrathecal/intraventricular methotrexate therapy.

  The Medical journal of Australia 19820918

• [The combination chemotherapy of vincristine, methotrexate, ACNU, and adriamycin for anaplastic carcinoma of the lung].

  Gan to kagaku ryoho. Cancer & chemotherapy 19820701

• Neurologic and cardiac toxicity following iv application of methotrexate.

  Cancer treatment reports 19820701

• Activity of sulfa drugs and dihydrofolate reductase inhibitors against Candida albicans.

  Experientia 19820415

• Cranial computed tomography during treatment of childhood lymphocytic leukemia. Factors predisposing to abnormalities.

  Acta paediatrica Scandinavica 19820301

• Syntheses of alpha- and gamma-substituted amides, peptides, and esters of methotrexate and their evaluation as inhibitors of folate metabolism.

  Journal of medicinal chemistry 19820201

• Galactose tolerance test and methotrexate-induced liver fibrosis and cirrhosis in patients with psoriasis.

  Acta dermato-venereologica 19820101

• Sequential chemotherapy of advanced colorectal cancer with standard or high-dose methotrexate followed by 5-fluorouracil.

  Medical and pediatric oncology 19820101

• Androgen priming and cytotoxic chemotherapy in advanced prostatic cancer.

  Cancer chemotherapy and pharmacology 19820101

• Sudden cardiac death following adriamycin therapy.

  Cancer 19810701

• Focal encephalopathy following methotrexate therapy. Administration via a misplaced intraventricular catheter.

  Archives of neurology 19810701

• Increased therapeutic index using moderate dose methotrexate and leucovorin twice weekly vs. weekly high dose methotrexate-leucovorin in patients with advanced squamous carcinoma of the head and neck: a safe new effective regimen.

  Cancer 19810515

• Life-threatening neuropathy and hepatotoxicity in infants during induction therapy for acute lymphoblastic leukemia.

  The Journal of pediatrics 19810401

• [A case of leucoencephalopathy caused by the intraventricular administration of methotrexate--follow-up analysis by computed tomography (author's transl)].

  Rinsho hoshasen. Clinical radiography 19810401

• [Disturbances of coagulation following high-dosage methotrexate with citrovorum factor rescue in patients with osteogenous sarcoma. (author's transl)].

  Klinische Padiatrie 19810301

• Progression of methotrexate-induced leukoencephalopathy in children with leukemia.

  Medical and pediatric oncology 19810101

• [Methotrexate-induced liver cirrhosis in psoriasis. Determination of tissue type and histopathological assessment].

  Ugeskrift for laeger 19800801

• Spindle cell cancer of bladder during cyclophosphamide therapy for Wegener's granulomatosis.

  The American journal of surgical pathology 19800401

• Methotrexate induced liver cirrhosis. Studies including serial liver biopsies during continued treatment.

  The British journal of dermatology 19800401

• Evaluation of nonhormonal cytotoxic chemotherapy in the Nb rat (Pr-90) prostatic carcinoma.

  Cancer 19800215

• HLA antigens in methotrexate-induced liver cirrhosis.

  Acta dermato-venereologica 19800101

• Chronic methotrexate toxicity to the central nervous system.

  Clinical bulletin 19800101

• Leukoencephalopathy following high-dose iv methotrexate chemotherapy with leucovorin rescue.

  Cancer treatment reports 19800101

• Triamterene-induced immune haemolytic anaemia with acute intravascular haemolysis and acute renal failure.

  Scandinavian journal of haematology 19790801

• [Acute lymphatic leukaemia in children: re-examination after remission of at least five years (author's transl)].

  Deutsche medizinische Wochenschrift (1946) 19790720

• Combination chemotherapy with vincristine and methotrexate for advanced refractory breast cancer.

  Cancer 19790701

• [Transient cerebral manifestations induced by intrathecal injection of methotrexate].

  La Nouvelle presse medicale 19790210

• Intrathecal methotrexate induced meningitis.

  Indian pediatrics 19790101

• [Non-leukemic disease of the central nervous system in children with acute lymphoblastic leukemia. II. Methotrexate-induced encephalopathy (author's transl)].

  Monatsschrift fur Kinderheilkunde 19781201

• Methotrexate encephalopathy. A neuropathologic study.

  Human pathology 19781101

• Acute encephalopathy after initiation of cranial irradiation for meningeal leukaemia.

  Lancet (London, England) 19781014

• The use of Adriamycin and mehtotrexate in carcinoma of the cervix. The development of a safe effective regimen.

  Obstetrics and gynecology 19780901

• Encephalomyelopathy following intrathecal methotrexate treatment in a child with acute leukemia.

  Cancer 19780901

• Leucoencephalopathy in patients on methotrexate.

  Lancet (London, England) 19780701

• Seizures following intrathecal cytosine arabinoside in young children with acute lymphoblastic leukemia.

  Cancer 19780701

• Methotrexate-induced renal failure and ineffectiveness of peritoneal dialysis.

  Archives of internal medicine 19780701

• Transient cerebral dysfunction following chemotherapy for osteogenic sarcoma.

  Annals of neurology 19780501

• Cerebromedullospinal disconnection after intraventricular methotrexate.

  Southern medical journal 19780401

• Intrathecal methotrexate causing paraplegia in a middle-aged woman.

  Acta haematologica 19780101

• Accidental intrathecal administration of vincristine.

  Medical and pediatric oncology 19780101

• Methotrexate-induced ventriculitis: appearance on routine radionculide scan and emission computed tomography.

  Clinical nuclear medicine 19780101

• Leukoencephalopathy following high-dose intravenous methotrexate chemotherapy: quantitative assessment of white matter attenuation using computed tomography.

  Neuroradiology 19780101

• Hepatoma in a child with methotrexate-induced hepatic fibrosis.

  JAMA 19771212

• Intracranial calcifications in childhood leukemia. An association with systemic chemotherapy.

  The Journal of pediatrics 19771201

• Methotrexate-induced sudden fatal pulmonary reaction.

  Cancer 19771001

• Chronic toxicity of methotrexate in rats: partial to complete projection of the liver by choline: Brief communication.

  Journal of the National Cancer Institute 19770901

• Morphogenesis of fibrosis and cirrhosis in methotrexate-treated patients with psoriasis.

  The American journal of surgical pathology 19770901

• Osteogenic sarcoma in a patient with aplastic anemia.

  Southern medical journal 19770701

• Liver biopsies from psoriatics related to methotrexate therapy. 3. Findings in post-methotrexate liver biopsies from 160 psoriatics.

  Acta pathologica et microbiologica Scandinavica. Section A, Pathology 19770701

• Acidic dissociation constants of folic acid, dihydrofolic acid, and methotrexate.

  The Journal of biological chemistry 19770610

• Methotrexate hepatotoxicity in children with leukemia.

  The Journal of pediatrics 19770601

• Computer assisted tomography in methotrexate encephalopathy.

  Journal of computer assisted tomography 19770401

• Hepatotoxicity in Wistar rats following chronic methotrexate administration: a model of human reaction.

  Journal of the National Cancer Institute 19770401

• Neuraxonal dystrophy of the brain in patients receiving antineoplastic chemotherapy.

  Acta neuropathologica 19770331

• Cerebral calcifications associated with intrathecal methotrexate therapy in acute lymphocytic leukemia.

  The Journal of pediatrics 19770301

• Computed tomographic appearance of methotrexate-induced necrotizing leukoencephalopathy.

  Radiology 19770201

• Thymidylate synthetase activity in the Novikoff hepatoma.

  Cancer research 19761201

• Current overview of EORTC clinical trials with tamoxifen.

  Cancer treatment reports 19761001

• Systemic chemotherapy for psoriasis: a national survey.

  Archives of dermatology 19760701

• Chemotherapy of psoriasis: ten years of experience.

  International journal of dermatology 19760601

• Letter: Vasculitis as a complication of high-dose methotrexate in the treatment of acute leukemia.

  American journal of diseases of children (1960) 19760601

• Paraplegia following intrathecal methotrexate: report of a case and review of the literature.

  Cancer 19760401

• Cerebral calcifications associated with intrathecal methotrexate therapy in acute lymphocytic leukemia.

  The Journal of pediatrics 19760401

• Effects of chemotherapy on the central nervous system. A study of parenteral methotrexate in long-term survivors of leukemia and lymphoma in childhood.

  Cancer 19760201

• [Disseminated necrotizing leukoencephalopathy following intrathecal methotrexate in childhood leukemia (author's transl)].

  Fukuoka igaku zasshi = Hukuoka acta medica 19760101

• Cytogenetic studies in a patient with acute granulocytic leukemia of seven and one-half years duration.

  Blood 19751101

• [Carcinoma of the liver in a child after seven-year complete remission of acute lymphoblastic leukaemia(author's transl)].

  Deutsche medizinische Wochenschrift (1946) 19750905

• Brain damage after intrathecal methotrexate.

  Journal of neurology, neurosurgery, and psychiatry 19750801

• Azaribine therapy for psoriasis. Evaluation of potential effects on the liver and other organ systems.

  Archives of dermatology 19750701

• The structure of dihydrofolate reductase. I. Inactivation of bacterial dihydrofolate reductase concomitant with modification of a methionine residue at the active site.

  The Journal of biological chemistry 19750225

• Intracerebral calcifications appearing during the course of acute lymphocytic leukemia treated with methotrexate and X-rays.

  Cancer 19750201

• Liver biopsy in methotrexate-treated psoriatics-a re-evalution.

  Acta dermato-venereologica 19750101

• Immunosuppressive and cytotoxic chemotherapy: long-term complications.

  Annals of internal medicine 19750101

• Hepatic drug metabolism and adverse hepatic drug reactions.

  Veterinary pathology 19750101

• Phenolization of bladder in treatment of massive intractable hematuria.

  Urology 19750101

• Treatment of advanced carcinoma of the cervix with adriamycin and methotrexate combined.

  Obstetrics and gynecology 19741001

• Methotrexate induced liver disease in psoriasis.

  The British journal of dermatology 19740601

• Leukoencephalopathy following the administration of methotrexate into the cerebrospinal fluid in the treatment of primary brain tumors.

  Cancer 19740401

• Proceedings: Daunorubicin cardiac toxicity in children with acute lymphocytic leukemia.

  Cancer 19740201

• Combination therapy in 130 patients with acute lymphoblastic leukemia (protocol 06 LA 66-Paris).

  Cancer research 19731201

• Paraplegia following intrathecal methotrexate.

  The Journal of pediatrics 19731201

• Liver injury associated with methotrexate therapy for psoriasis.

  Mayo Clinic proceedings 19731101

• Methotrexate-induced bone pain in childhood leukemia.

  American journal of diseases of children (1960) 19731001

• Irradiation, methotrexate toxicity, and the treatment of meningeal leukaemia.

  Lancet (London, England) 19730929

• Methoxyflurane nephrotoxicity. A study of dose response in man.

  JAMA 19730924

• Cirrhosis following methotrexate administration for psoriasis.

  The Medical journal of Australia 19730908

• Postoperative intracavitary chemotherapy of malignant gliomas. A preliminary study using methotrexate.

  Journal of neurosurgery 19730901

• Hepatotoxicity of long-term methotrexate therapy for psoriasis.

  Archives of internal medicine 19730901

• Azathioprine in psoriasis.

  Proceedings of the Royal Society of Medicine 19730801

• Psoriasis-liver-methotrexate interactions.

  Archives of dermatology 19730701

• Cancer chemotherapy by intra-arterial infusion with adriamycin.

  Journal of surgical oncology 19730501

• Seizures associated with vincristine sulfate therapy.

  The Journal of pediatrics 19730401

• [Serious neurological syndrome observed after first intraspinal administration of methotrexate in a child with acute lymphatic leukemia].

  Minerva pediatrica 19730331

• Necrotizing encephalopathy following intraventricular instillation of methotrexate.

  Archives of neurology 19730201

• Long-term effects of hydroxyurea in psoriases.

  British medical journal 19721209

• Structural and functional abnormalities of the liver in psoriasis before and during methotrexate therapy.

  The British journal of dermatology 19721201

• Methotrexate meningitis.

  Lancet (London, England) 19720923

• Intensive combined chemotherapy and radiotherapy in patients with nonresectable bronchogenic carcinoma.

  Cancer 19720801

• Methotrexate-associated liver disease in psoriatic patients.

  Northwest medicine 19720801

• Encephalopathy in acute leukaemia associated with methotrexate therapy.

  Archives of disease in childhood 19720601

• Cirrhosis following prolonged treatment of psoriasis with methotrexate orally.

  Southern medical journal 19720401

• Methotrexate hepatotoxicity in psoriasis--comparison of different dose regimens.

  British medical journal 19720311

• Combination sequential chemotherapy in advanced reticulum cell sarcoma.

  Cancer 19720301

• Treatment of Reiter's syndrome with methotrexate.

  Canadian Medical Association journal 19711204

• Remission maintenance therapy for meningeal leukemia: intrathecal methotrexate vs. intravenous bis-nitrosourea.

  Blood 19711201

• Hepatic structure and function in psoriasis before and after treatment with methotrexate.

  Gut 19711001

• Severe neurological damage associated with methotrexate therapy.

  Lancet (London, England) 19710904

• Methotrexate and hepatic disease.

  JAMA 19710621

• Methotrexate, alcohol, and liver damage.

  British medical journal 19710417

• Liver damage due to methotrexate in patients with psoriasis.

  British medical journal 19710320

• Comparison of CNS-leukaemia in children with acute leukaemia, induced either with rubidomycin or L-asparaginase.

  Padiatrie und Padologie 19710101

• Clinical note: allergic reaction to daunomycin (NSC-82151).

  Cancer chemotherapy reports 19701201

• Pityriasis rubra pilaris. Prolonged treatment with methotrexate.

  Archives of dermatology 19701201

• Evaluation of possible chronic hepatotoxicity from methotrexate for psoriasis.

  Archives of dermatology 19701201

• [Liver damage during methotrexate treatment of psoriasis].

  Nordisk medicin 19700917

• Methotrexate therapy of head and neck cancer: improvement in therapeutic index by the use of leucovorin 'rescue'.

  Cancer research 19700601

• Liver biopsy in psoriasis.

  The British journal of dermatology 19700301

• Intrathecal methotrexate.

  Lancet (London, England) 19700207

• Intermittent high dose oral methotrexate therapy in psoriasis.

  The British journal of dermatology 19700101

• Parenteral methotrexate in psoriasis. A report on the efficacy and toxicity of long-term intermittent treatment.

  Archives of dermatology 19691201

• Cirrhosis caused by methotrexate in the treatment of psoriasis.

  Archives of dermatology 19691101

• Cirrhosis following methotrexate administration for psoriasis.

  Archives of dermatology 19691101

• Development of myeloblastoma with massive breast and ovarian involvement during remission in acute leukemia.

  Cancer 19691001

• Mechanism of pyrimethamine-induced megaloblastosis in human bone marrow.

  The New England journal of medicine 19690612

• Vincristine-induced neuropathy. A clinical study of fifty leukemic patients.

  Neurology 19690401

• Neurofibrillary degeneration induced by vincristine therapy.

  Archives of neurology 19690201

• Methotrexate for psoriasis in weekly oral doses.

  Archives of dermatology 19690101

• Renal toxicity of methotrexate.

  Cancer 19690101

• Cirrhosis associated with methotrexate treatment of psoriasis.

  JAMA 19681111

• Neuropathy in lymphoblastic leukemia treated with vincristine.

  Archives of neurology 19670401

• The treatment of psoriasis with methotrexate.

  The British journal of dermatology 19670201

• Psoriasis and folic acid antagonists.

  The British journal of dermatology 19670201

• Megaloblastic anemia and methotrexate therapy.

  British medical journal 19660910