599-04-2 | D-(-)-Pantolactone

Packsize	Purity	Availability	Price	Discounted Price
5g	98%	in stock	$6.00	$4.00
10g	98%	in stock	$8.00	$5.00
25g	98%	in stock	$13.00	$9.00
100g	98%	in stock	$36.00	$25.00
250g	98%	in stock	$72.00	$50.00
500g	98%	in stock	$99.00	$69.00

Description

• Catalog Number: AB45832
• Chemical Name: D-(-)-Pantolactone
• CAS Number: 599-04-2
• Molecular Formula: C6H10O3
• Molecular Weight: 130.1418
• MDL Number: MFCD00005392
• SMILES: O[C@H]1C(=O)OCC1(C)C

Computed Properties

• Complexity: 139
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 9
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 1
• XLogP3: 0.5

Literature

• L-pantoyl lactone dehydrogenase from Rhodococcus erythropolis: genetic analyses and application to the stereospecific oxidation of L-pantoyl lactone.

  Applied microbiology and biotechnology 20120701

• Synthesis of molluscicidal agent cyanolide a macrolactone from D-(-)-pantolactone.

  The Journal of organic chemistry 20110204

• Biocatalytic properties of a recombinant Fusarium proliferatum lactonase with significantly enhanced production by optimal expression in Escherichia coli.

  Applied biochemistry and biotechnology 20101001

• A striking exception to the chelate model for acyclic diastereocontrol: efficient access to a versatile propargyl alcohol for chemical synthesis.

  Molecules (Basel, Switzerland) 20091215

• Asymmetric histidine-catalyzed cross-aldol reactions of enolizable aldehydes: access to defined configured quaternary stereogenic centers.

  Journal of the American Chemical Society 20091125

• Synthesis and absolute configuration of novel N,O-psiconucleosides using (R)-N-phenylpantolactam as a resolution agent.

  The Journal of organic chemistry 20080905

• Total synthesis and antitumor activity of ZK-EPO: the first fully synthetic epothilone in clinical development.

  Angewandte Chemie (International ed. in English) 20061204

• Directed evolution and characterization of a novel D-pantonohydrolase from Fusarium moniliforme.

  Journal of agricultural and food chemistry 20060809

• Practical resolution system for DL-pantoyl lactone using the lactonase from Fusarium oxysporum.

  Journal of biotechnology 20050721

• Total synthesis of polycavernoside A, a lethal toxin of the red alga Polycavernosa tsudai.

  The Journal of organic chemistry 20050708

• Exogenous supply of pantoyl lactone to excised leaves increases their pantothenate levels.

  Annals of botany 20050501

• Gene cloning and overexpression of two conjugated polyketone reductases, novel aldo-keto reductase family enzymes, of Candida parapsilosis.

  Applied microbiology and biotechnology 20040401

• A formal synthesis of (-)-mycalamide A.

  Journal of the American Chemical Society 20040114

• Optical rotation of noncovalent aggregates.

  Journal of the American Chemical Society 20031224

• Practical asymmetric synthesis of a potent Cathepsin K inhibitor. Efficient palladium removal following Suzuki coupling.

  The Journal of organic chemistry 20030404

• (R)-2,4-Dihydroxybutyramide seco-pseudonucleosides: new versatile homochiral synthons for synthesis of modified oligonucleotides.

  Organic letters 20021226

• Synthesis of (+/-)-5-epi-citreoviral and (+/-)-citreoviral and the kinetic resolution of an allylic silane by a [3 + 2] annulation.

  Organic letters 20020822

• Double diastereoselective intramolecular cyclopropanation to P-chiral [3.1.0]-bicyclic phosphonates.

  Organic letters 20020711

• A screening system for enantioselective enzymes based on differential cell growth.

  Chemical communications (Cambridge, England) 20020707

• Synthesis of diastereomerically enriched 2-bromoesters and their reaction with nucleophiles.

  Chirality 20010201