604-33-1 | Cholesteryl linoleate

Packsize	Purity	Availability	Price	Discounted Price
50mg	95%	in stock	$43.00	$30.00
100mg	95%	in stock	$80.00	$56.00
250mg	95%	in stock	$155.00	$108.00
500mg	95%	in stock	$287.00	$201.00
1g	95%	in stock	$377.00	$264.00

Description

• Catalog Number: AB72006
• Chemical Name: Cholesteryl linoleate
• CAS Number: 604-33-1
• Molecular Formula: C45H76O2
• Molecular Weight: 649.0837
• MDL Number: MFCD00003644
• SMILES: CCCCC/C=C\C/C=C\CCCCCCCC(=O)O[C@H]1CC[C@]2(C(=CC[C@@H]3[C@@H]2CC[C@]2([C@H]3CC[C@@H]2[C@@H](CCCC(C)C)C)C)C1)C

Computed Properties

• Complexity: 1020
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 8
• Defined Bond Stereocenter Count: 2
• Heavy Atom Count: 47
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 21
• XLogP3: 15.9

Literature

• Insights into myalgic encephalomyelitis/chronic fatigue syndrome phenotypes through comprehensive metabolomics.

  Scientific reports 20180101

• Lipidomic analyses of female mice lacking hepatic lipase and endothelial lipase indicate selective modulation of plasma lipid species.

  Lipids 20140601

• The Chlamydia trachomatis CT149 protein exhibits esterase activity in vitro and catalyzes cholesteryl ester hydrolysis when expressed in HeLa cells.

  Microbes and infection 20121101

• Pyripyropene A, an acyl-coenzyme A:cholesterol acyltransferase 2-selective inhibitor, attenuates hypercholesterolemia and atherosclerosis in murine models of hyperlipidemia.

  Arteriosclerosis, thrombosis, and vascular biology 20110501

• Intramural coronary lipid injection induces atheromatous lesions expressing proinflammatory chemokines: implications for the development of a porcine model of atherosclerosis.

  Cardiovascular revascularization medicine : including molecular interventions 20110101

• Cannabidiol-2',6'-dimethyl ether as an effective protector of 15-lipoxygenase-mediated low-density lipoprotein oxidation in vitro.

  Biological & pharmaceutical bulletin 20110101

• Modification of composition of a nanoemulsion with different cholesteryl ester molecular species: effects on stability, peroxidation, and cell uptake.

  International journal of nanomedicine 20100101

• Macrophage activation induces formation of the anti-inflammatory lipid cholesteryl-nitrolinoleate.

  The Biochemical journal 20090101

• Lipids including cholesteryl linoleate and cholesteryl arachidonate contribute to the inherent antibacterial activity of human nasal fluid.

  Journal of immunology (Baltimore, Md. : 1950) 20080915

• Roles of endogenously synthesized sterols in the endocytic pathway.

  The Journal of biological chemistry 20060811

• The reduction of cholesteryl linoleate in lipoproteins: an index of clinical severity in beta-thalassemia/Hb E.

  Clinical chemistry and laboratory medicine 20060101

• Selective uptake and efflux of cholesteryl linoleate in LDL by macrophages expressing 12/15-lipoxygenase.

  Biochemical and biophysical research communications 20051209

• Endovascular needle injection of cholesteryl linoleate into the arterial wall produces complex vascular lesions identifiable by intravascular ultrasound: early development in a porcine model of vulnerable plaque.

  Coronary artery disease 20050601

• Identification and analysis of products formed from phospholipids in the free radical oxidation of human low density lipoproteins.

  Journal of lipid research 20050201

• Sequence of the lid affects activity and specificity of Candida rugosa lipase isoenzymes.

  Protein science : a publication of the Protein Society 20031001

• Cholesteryl ester oxidation products in atherosclerosis.

  Molecular aspects of medicine 20030101

• Oxidized cholesteryl linoleates stimulate endothelial cells to bind monocytes via the extracellular signal-regulated kinase 1/2 pathway.

  Arteriosclerosis, thrombosis, and vascular biology 20020401

• Preparation of the addition products of alpha-tocopherol with cholesteryl linoleate-peroxyl radicals.

  Bioscience, biotechnology, and biochemistry 20020301

• Estradiol esterification in the human preovulatory follicle.

  Steroids 20011201