608-66-2 | Galactitol

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$16.00	$11.00
5g	98%	in stock	$25.00	$17.00
25g	98%	in stock	$25.00	$17.00
100g	98%	in stock	$43.00	$30.00
1kg	98%	in stock	$383.00	$268.00
5kg	98%	in stock	$1,776.00	$1,243.00

Description

• Catalog Number: AG94179
• Chemical Name: Galactitol
• CAS Number: 608-66-2
• Molecular Formula: C6H14O6
• Molecular Weight: 182.1718
• MDL Number: MFCD00064288
• SMILES: OC[C@H]([C@@H]([C@@H]([C@H](CO)O)O)O)O

Computed Properties

• Complexity: 105
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 4
• Heavy Atom Count: 12
• Hydrogen Bond Acceptor Count: 6
• Hydrogen Bond Donor Count: 6
• Rotatable Bond Count: 5
• XLogP3: -3.1

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  Acta paediatrica (Oslo, Norway : 1992) 20060201

• Crystal structures and spectroscopic characterization of galactitol complexes of trivalent lanthanide and divalent alkaline earth chlorides.

  Carbohydrate research 20060116

• Proton MR spectroscopy and imaging of a galactosemic patient before and after dietary treatment.

  AJNR. American journal of neuroradiology 20060101

• Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.

  Molecular systems biology 20060101

• Pathophysiology of impaired ovarian function in galactosaemia.

  Human reproduction update 20060101

• Chemical constituents of Selinum cryptotaenium.

  Journal of Asian natural products research 20060101

• H-NS controls metabolism and stress tolerance in Escherichia coli O157:H7 that influence mouse passage.

  BMC microbiology 20060101

• The use of comparative genomic hybridization to characterize genome dynamics and diversity among the serotypes of Shigella.

  BMC genomics 20060101

• Oxygen limitation modulates pH regulation of catabolism and hydrogenases, multidrug transporters, and envelope composition in Escherichia coli K-12.

  BMC microbiology 20060101

• inGeno--an integrated genome and ortholog viewer for improved genome to genome comparisons.

  BMC bioinformatics 20060101

• The biochemical differentiation of Enterobacter sakazakii genotypes.

  BMC microbiology 20060101

• [Study on the chemical constituents of Buddleja purdomii].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20051101

• Galactosemia in Thai patient at Phramongkutklao Hospital: a case report.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20051101

• An updated review of the long-term neurological effects of galactosemia.

  Pediatric neurology 20050901

• Suckling rat brain regional distribution of acetylcholinesterase activity in galactosaemia in vitro.

  Metabolic brain disease 20050901

• Characterization of two major groups of diarrheagenic Escherichia coli O26 strains which are globally spread in human patients and domestic animals of different species.

  FEMS microbiology letters 20050815

• [Characterization and identification of Ralstonia solanacearum by ion-exchange chromatography].

  Se pu = Chinese journal of chromatography 20050701

• Desulfurococcus fermentans sp. nov., a novel hyperthermophilic archaeon from a Kamchatka hot spring, and emended description of the genus Desulfurococcus.

  International journal of systematic and evolutionary microbiology 20050501

• Mg2+-ATPase activity in suckling rat brain regions in galactosaemia in vitro. L-Cysteine and glutathione effects.

  Toxicology in vitro : an international journal published in association with BIBRA 20050301

• Suckling rat brain regional distribution of Na+,K+-atpase activity in the in vitro galactosaemia: the effect of L-cysteine and glutathione.

  Metabolic brain disease 20050301

• The protective effect of L-cysteine and glutathione on the adult and aged rat brain (Na+,K+)-ATPase and Mg2+-ATPase activities in galactosemia in vitro.

  Metabolic brain disease 20050301

• Galactitol and galactonate in red blood cells of children with the Duarte/galactosemia genotype.

  Molecular genetics and metabolism 20050201

• The effect of diet on total antioxidant status, erythrocyte membrane Na+,K+-ATPase and Mg2+-ATPase activities in patients with classical galactosaemia.

  Clinical nutrition (Edinburgh, Scotland) 20050201

• Four new prenylated isoflavonoids in Tadehagi triquetrum.

  Journal of agricultural and food chemistry 20050126

• A comprehensive update of the sequence and structure classification of kinases.

  BMC structural biology 20050101

• Galactosaemia: early treatment with an elemental formula.

  Journal of inherited metabolic disease 20050101

• Quantitative determination of endogenous sorbitol and fructose in human nerve tissues by atmospheric-pressure chemical ionization liquid chromatography/tandem mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20050101

• Analysis of polyols in urine by liquid chromatography-tandem mass spectrometry: a useful tool for recognition of inborn errors affecting polyol metabolism.

  Journal of inherited metabolic disease 20050101

• Genetic diversity among Pasteurella multocida strains of avian, bovine, ovine and porcine origin from England and Wales by comparative sequence analysis of the 16S rRNA gene.

  Microbiology (Reading, England) 20041201

• High tolerance for oral galactose in classical galactosaemia: dietary implications.

  Archives of disease in childhood 20041101

• Trichosporon mycotoxinivorans sp. nov., a new yeast species useful in biological detoxification of various mycotoxins.

  Systematic and applied microbiology 20041101

• Anaphylaxis to excipient mannitol: evidence for an immunoglobulin E-mediated mechanism.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20041001

• Cognitive strengths and weaknesses in children and adolescents homozygous for the galactosemia Q188R mutation: a descriptive study.

  Neuropsychology 20041001

• Identification of sorbitol transporters expressed in the phloem of apple source leaves.

  Plant & cell physiology 20040801

• Aeromonas spp. and infectious diarrhea, Hong Kong.

  Emerging infectious diseases 20040801

• Characterization of Neisseria meningitidis isolates collected from 1974 to 2003 in Japan by multilocus sequence typing.

  Journal of medical microbiology 20040701

• The genes and enzymes for the catabolism of galactitol, D-tagatose, and related carbohydrates in Klebsiella oxytoca M5a1 and other enteric bacteria display convergent evolution.

  Molecular genetics and genomics : MGG 20040701

• Protective effect of L-cysteine and glutathione on the modulated suckling rat brain Na+, K+, -ATPase and Mg2+ -ATPase activities induced by the in vitro galactosaemia.

  Pharmacological research 20040501

• Ophthalmoscopic and morphogenetic changes in rat lens induced by galactose: attenuation by pyruvate.

  Diabetes, obesity & metabolism 20040501

• The metabolic role and evolution of L-arabinitol 4-dehydrogenase of Hypocrea jecorina.

  European journal of biochemistry 20040501

• Autodisplay of active sorbitol dehydrogenase (SDH) yields a whole cell biocatalyst for the synthesis of rare sugars.

  Chembiochem : a European journal of chemical biology 20040402

• Galactonate determination in urine by stable isotope dilution gas chromatography-mass spectrometry.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040305

• tRNA-intergenic spacer PCR for the identification of Pasteurella and Mannheimia spp.

  Veterinary microbiology 20040305

• Galactitol and galactonate accumulation in heart and skeletal muscle of mice with deficiency of galactose-1-phosphate uridyltransferase.

  Molecular genetics and metabolism 20040201

• The galactokinase of Hypocrea jecorina is essential for cellulase induction by lactose but dispensable for growth on d-galactose.

  Molecular microbiology 20040201

• The alternative D-galactose degrading pathway of Aspergillus nidulans proceeds via L-sorbose.

  Archives of microbiology 20040101

• Age dependence of endogenous galactose formation in Q188R homozygous galactosemic patients.

  Molecular genetics and metabolism 20040101

• Galactitol and galactonate in red blood cells of galactosemic patients.

  Molecular genetics and metabolism 20031101

• D-xylose metabolism in Hypocrea jecorina: loss of the xylitol dehydrogenase step can be partially compensated for by lad1-encoded L-arabinitol-4-dehydrogenase.

  Eukaryotic cell 20031001

• [The inhibitory effect of aldose reductase inhibitor for proliferation in the lens epithelial cells of rat sugar cataract].

  Nippon Ganka Gakkai zasshi 20031001

• Sugar complexes with neodymium nitrate. Spectroscopic and structural studies of two Nd(NO3)3-galactitol complexes.

  Carbohydrate research 20030910

• Hyperinsulinism in infancy: understanding the pathophysiology.

  The international journal of biochemistry & cell biology 20030901

• Transgenic mice overexpressing aldose reductase in Schwann cells show more severe nerve conduction velocity deficit and oxidative stress under hyperglycemic stress.

  Molecular and cellular neurosciences 20030801

• Apoptotic cell death in the lens epithelium of rat sugar cataract.

  Experimental eye research 20030701

• New derivatives of D-mannaric and galactaric acids. Synthesis of a new stereoregular Nylon 66 analog from carbohydrate-based monomers having the D-manno configuration.

  Carbohydrate research 20030501

• Verbal dyspraxia and galactosemia.

  Pediatric research 20030301

• NADPH-dependent reductases and polyol formation in human leukemia cell lines.

  Chemico-biological interactions 20030201

• Sugar interaction with metal ion: crystal structure and spectroscopic study of SrCl2.galactitol.4H2O.

  Journal of inorganic biochemistry 20030201

• [Mutation P28T in gene GK1 as the cause of a familial galactokinase deficiency].

  Archivos de la Sociedad Espanola de Oftalmologia 20030201

• Insights into the pathogenesis of galactosemia.

  Annual review of nutrition 20030101

• [Effect of various sources of nitrogen and carbon on the biosynthesis of proteolytic enzymes in a culture of Aspergillus awamori 21/96].

  Prikladnaia biokhimiia i mikrobiologiia 20030101

• Minalrestat and leukocyte migration in diabetes mellitus.

  Diabetes/metabolism research and reviews 20030101

• Renal excretion of galactose and galactitol in patients with classical galactosaemia, obligate heterozygous parents and healthy subjects.

  Journal of inherited metabolic disease 20030101

• Sugar recognition by human galactokinase.

  BMC biochemistry 20030101

• Extending knowledge of Escherichia coli metabolism by modeling and experiment.

  Genome biology 20030101

• Stable-isotope dilution analysis of galactose metabolites in human erythrocytes.

  Rapid communications in mass spectrometry : RCM 20030101

• Mutations in galactose-1-phosphate uridyltransferase gene in patients with idiopathic presenile cataract.

  Journal of inherited metabolic disease 20030101

• Bioinformatic analyses of the bacterial L-ascorbate phosphotransferase system permease family.

  Journal of molecular microbiology and biotechnology 20030101

• Stereoselective oxidation of aliphatic diols and reduction of hydroxy-ketones with galactitol dehydrogenase from Rhodobacter sphaeroides D.

  Communications in agricultural and applied biological sciences 20030101

• Metabolism of 13C galactose by lymphoblasts from patients with galactosemia determined by NMR spectroscopy.

  Molecular genetics and metabolism 20021201

• Clinical features of galactokinase deficiency: a review of the literature.

  Journal of inherited metabolic disease 20021201

• The in vitro effects of galactose and its derivatives on rat brain Mg2+-ATPase activity.

  Pharmacology & toxicology 20021101

• Sugar interaction with metal ions. The coordination behavior of neutral galactitol to Ca(II) and lanthanide ions.

  Carbohydrate research 20020909

• The solvent-free thermal dehydration of hexitols on zeolites.

  Carbohydrate research 20020816

• Identification of galactitol and galactonate in red blood cells by gas chromatography/mass spectrometry.

  Clinica chimica acta; international journal of clinical chemistry 20020801

• Iridoid glucosides from Veronica hederifolia.

  Chemical & pharmaceutical bulletin 20020801

• Phenylethanoid and iridoid glycosides from Veronica persica.

  Chemical & pharmaceutical bulletin 20020601

• [FTIR and FT-Raman spectroscopic investigation on two complexes of La3+ with galactitol].

  Guang pu xue yu guang pu fen xi = Guang pu 20020601

• Two class II D-tagatose-bisphosphate aldolases from enteric bacteria.

  Archives of microbiology 20020501

• A biodegradable injectable implant sustains systemic and ocular delivery of an aldose reductase inhibitor and ameliorates biochemical changes in a galactose-fed rat model for diabetic complications.

  Pharmaceutical research 20020301

• Osmoregulatory alterations in taurine uptake by cultured human and bovine lens epithelial cells.

  Investigative ophthalmology & visual science 20020201

• Galactokinase deficiency: a case report.

  Journal of pediatric ophthalmology and strabismus 20020101

• Characterization of Escherichia coli strains associated with canine pyometra.

  Polish journal of veterinary sciences 20020101

• Selective pericyte degeneration in the retinal capillaries of galactose-fed dogs results from apoptosis linked to aldose reductase-catalyzed galactitol accumulation.

  Journal of diabetes and its complications 20020101

• The effect of galactose metabolic disorders on rat brain Na+,K+-ATPase activity.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20020101

• Phenotypic characterization of Microsporum canis isolated from cats and dogs.

  Mycoses 20011201

• Polyphasic investigation of the diversity within Lactobacillus plantarum related strains revealed two L. plantarum subgroups.

  Systematic and applied microbiology 20011201

• Proton magnetic resonance spectroscopy of brain metabolites in galactosemia.

  Annals of neurology 20010801

• Intrinsic inhibition of aldose reductase.

  Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20010801

• Galactose metabolism in normal human lymphoblasts studied by (1)H, (13)C and (31)P NMR spectroscopy of extracts.

  NMR in biomedicine 20010501

• Galactose metabolism in mice with galactose-1-phosphate uridyltransferase deficiency: sucklings and 7-week-old animals fed a high-galactose diet.

  Molecular genetics and metabolism 20010401

• [Development of chromogenic agar medium for isolation of enterohaemorrhagic Escherichia coli O26].

  Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases 20010401

• Asaia siamensis sp. nov., an acetic acid bacterium in the alpha-proteobacteria.

  International journal of systematic and evolutionary microbiology 20010301

• In vivo evidence of brain galactitol accumulation in an infant with galactosemia and encephalopathy.

  The Journal of pediatrics 20010201

• [Early childhood cataract in hereditary UDP-galactose-4-epimerase deficiency--a case report].

  Klinische Monatsblatter fur Augenheilkunde 20010201

• The role of aldose reductase in sugar cataract formation: aldose reductase plays a key role in lens epithelial cell death (apoptosis).

  Chemico-biological interactions 20010130

• Complexation of trivalent lanthanide cations by galactitol in the solid state. The crystal structure and an FT-IR study of 2NdCl3.galactitol.14H2O.

  Carbohydrate research 20010115

• Sugar interaction with metal ions. The crystal structure and Raman spectra study of SmCl3-galactitol complex.

  Journal of inorganic biochemistry 20010115

• Phenotypic characterization of Trichophyton rubrum isolates from two geographic locations in Brazil.

  European journal of epidemiology 20010101

• N-[5-(trifluoromethyl)-6-methoxy-1-naphthalenyl]thioxomethyl]- N-methylglycine (Tolrestat), a potent, orally active aldose reductase inhibitor.

  Journal of medicinal chemistry 19840301