611-10-9 | Ethyl 2-oxocyclopentanecarboxylate

Packsize	Purity	Availability	Price	Discounted Price
100g	97%	in stock	$11.00	$8.00
500g	97%	in stock	$49.00	$35.00

Description

• Catalog Number: AB46055
• Chemical Name: Ethyl 2-oxocyclopentanecarboxylate
• CAS Number: 611-10-9
• Molecular Formula: C8H12O3
• Molecular Weight: 156.1791
• MDL Number: MFCD00001412
• SMILES: CCOC(=O)C1CCCC1=O

Computed Properties

• Complexity: 174
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Undefined Atom Stereocenter Count: 1
• XLogP3: 0.9

Upstream Synthesis Route

Ethyl 2-oxocyclopentanecarboxylate is a versatile chemical compound commonly used in chemical synthesis for various applications. This compound serves as a key intermediate in the synthesis of numerous organic compounds, particularly in the preparation of pharmaceuticals, agrochemicals, and fine chemicals. Its unique structure and reactivity make it a valuable building block in organic synthesis.In chemical transformations, Ethyl 2-oxocyclopentanecarboxylate can undergo various reactions such as esterification, alkylation, and condensation, leading to the formation of complex molecular structures. Its functional groups enable it to participate in diverse reactions, allowing chemists to tailor the molecule to obtain specific desired products.One common application of Ethyl 2-oxocyclopentanecarboxylate is in the synthesis of heterocyclic compounds. By reacting with other reagents or functional groups, it can be used to construct rings containing oxygen, nitrogen, sulfur, or other elements, which are prevalent in many bioactive and pharmaceutical compounds.Additionally, this compound is employed in the preparation of chiral molecules and asymmetric synthesis. Its ability to act as a chiral precursor or building block facilitates the creation of enantiomerically pure compounds, crucial in the pharmaceutical industry for drug development.Overall, Ethyl 2-oxocyclopentanecarboxylate plays a pivotal role in modern organic chemistry, enabling chemists to access a wide range of structurally diverse and complex molecules through strategic synthetic pathways. Its versatility and reactivity make it a valuable tool for researchers and practitioners alike in the field of chemical synthesis.

Literature

• Cu(I)- and Cu(II)-catalyzed cyclo- and Michael addition reactions of unsaturated β-ketoesters.

  The Journal of organic chemistry 20110715

• From cyclopentanone oximes to bis[1,2,3]dithiazolo-s-indacenes, cyclopenta[c][1,2]thiazine, pentathiepino-, tetrathiino-, and thienocyclopenta[1,2,3]dithiazoles as a rich source of new materials.

  The Journal of organic chemistry 20051111

• Investigations into the metal species of the homogeneous iron(III) catalyzed Michael addition reactions.

  Physical chemistry chemical physics : PCCP 20050707

• Synthesis of bicyclo[4.n.1]alkanones.

  The Journal of organic chemistry 20041001

• Hydrogenation of cinchona alkaloids over supported Pt catalyst.

  Chirality 20030101

• Enantioselective Michael addition catalyzed by cinchona alkaloids.

  Chirality 20010101