611-13-2 | Methyl 2-furoate

Packsize	Purity	Availability	Price	Discounted Price
5g	95%	in stock	$19.00	$13.00
25g	95%	in stock	$28.00	$20.00
100g	95%	in stock	$60.00	$42.00
500g	95%	in stock	$249.00	$175.00

Description

• Catalog Number: AB75621
• Chemical Name: Methyl 2-furoate
• CAS Number: 611-13-2
• Molecular Formula: C6H6O3
• Molecular Weight: 126.11
• MDL Number: MFCD00003236
• SMILES: COC(=O)c1ccco1
• NSC Number: 35551

Computed Properties

• Complexity: 111
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 9
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• XLogP3: 1

Upstream Synthesis Route

Methyl furan-2-carboxylate, a versatile compound in chemical synthesis, serves as a vital building block in various reactions, owing to its unique structure and reactivity. With its electron-rich furan ring and carboxylate group, this compound finds applications in the synthesis of pharmaceuticals, agrochemicals, and materials.One of the prominent uses of methyl furan-2-carboxylate is in the production of heterocyclic compounds. By undergoing cyclization reactions with appropriate reagents, it can lead to the formation of diverse heterocycles, such as pyrroles, pyrazoles, and indoles. These heterocyclic motifs are prevalent in numerous bioactive molecules and natural products, making methyl furan-2-carboxylate a valuable tool in the synthesis of these compounds.Furthermore, methyl furan-2-carboxylate can act as a key intermediate in the preparation of esters, amides, and various functionalized derivatives. Through esterification or amidation reactions, it can be modified to introduce different substituents, altering the properties and functionality of the resulting compounds. This flexibility enables chemists to tailor molecules for specific applications, such as drug design or materials science.Overall, the strategic use of methyl furan-2-carboxylate in chemical synthesis highlights its significance as a versatile building block with wide-ranging applications in the creation of complex molecular structures.

Literature

• Chemical and biochemical study of industrially produced San Simón da Costa smoked semi-hard cow's milk cheeses: Effects of storage under vacuum and different modified atmospheres.

  Journal of dairy science 20100501

• 3-[4-(Benz-yloxy)phen-yl]-1-(2-fur-yl)-3-hydroxy-prop-2-en-1-one.

  Acta crystallographica. Section E, Structure reports online 20081201

• Enantioselective synthesis of furo[2,3-b]furans, a spongiane diterpenoid substructure.

  Organic letters 20051124

• Facile asymmetric synthesis of the core nuclei of xanthanolides, guaianolides, and eudesmanolides.

  Organic letters 20030320

• Enantioselective synthesis of (-)-roccellaric acid.

  Organic letters 20010503