611-53-0 | 4-Amino-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-iodopyrimidin-2(1H)-one

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$15.00	$10.00
5g	98%	in stock	$60.00	$42.00
10g	98%	in stock	$120.00	$84.00
25g	98%	in stock	$200.00	$140.00

Description

• Catalog Number: AB50924
• Chemical Name: 4-Amino-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-iodopyrimidin-2(1H)-one
• CAS Number: 611-53-0
• Molecular Formula: C9H12IN3O4
• Molecular Weight: 353.1137
• MDL Number: MFCD00038063
• SMILES: OC[C@H]1O[C@H](C[C@@H]1O)n1cc(I)c(nc1=O)N

Computed Properties

• Complexity: 398
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 3
• Heavy Atom Count: 17
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 2
• XLogP3: -0.7

Literature

• Improved synthesis and mutagenicity of oligonucleotides containing 5-hydroxymethylcytosine, 5-formylcytosine and 5-carboxylcytosine.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20111202

• Fluorescent pyrimidopyrimidoindole nucleosides: control of photophysical characterizations by substituent effects.

  The Journal of organic chemistry 20070706

• MIA (melanoma inhibitory activity) promoter mediated tissue-specific suicide gene therapy of malignant melanoma.

  Cancer gene therapy 20040601

• Asymmetric photocross-linking pattern of restriction endonuclease EcoRII to the DNA recognition sequence.

  The Journal of biological chemistry 20020419

• X-ray analyses of d(GCGAAAGC) and d(GXGAAAGCT), where X = 2'-deoxy-5-iodocytidine.

  Nucleic acids research. Supplement (2001) 20010101

• Efficacy of select antivirals against Cryptosporidium parvum in vitro.

  FEMS microbiology letters 19981101

• In vitro susceptibility of varicella-zoster virus to E-5-(2-bromovinyl)-2'-deoxyuridine and related compounds.

  Antimicrobial agents and chemotherapy 19820101

• Relative potencies of different anti-herpes agents in the topical treatment of cutaneous herpes simplex virus infection of athymic nude mice.

  Antimicrobial agents and chemotherapy 19791101

• Nucleosides. 110. Synthesis and antiherpes virus activity of some 2'-fluoro-2'-deoxyarabinofuranosylpyrimidine nucleosides.

  Journal of medicinal chemistry 19790101