612-62-4 | 2-Chloroquinoline

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$8.00	$5.00
5g	98%	in stock	$14.00	$10.00
10g	98%	in stock	$17.00	$12.00
25g	98%	in stock	$42.00	$30.00
100g	98%	in stock	$168.00	$117.00

Description

• Catalog Number: AB61927
• Chemical Name: 2-Chloroquinoline
• CAS Number: 612-62-4
• Molecular Formula: C9H6ClN
• Molecular Weight: 163.60364
• MDL Number: MFCD00006741
• SMILES: Clc1ccc2c(n1)cccc2
• NSC Number: 6163

Computed Properties

• Complexity: 138
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 1
• XLogP3: 2.7

Literature

• Synthesis and 3D-QSAR analysis of 2-chloroquinoline derivatives as H37 RV MTB inhibitors.

  Chemical biology & drug design 20131201

• Prion inhibition with multivalent PrPSc binding compounds.

  Biomaterials 20121001

• Discovery of a new antileishmanial hit in 8-nitroquinoline series.

  European journal of medicinal chemistry 20120801

• C-C bond formation at C-2 of a quinoline ring: synthesis of 2-(1H-indol-3-yl)quinoline-3-carbonitrile derivatives as a new class of PDE4 inhibitors.

  Bioorganic & medicinal chemistry 20120401

• Identification, design and biological evaluation of bisaryl quinolones targeting Plasmodium falciparum type II NADH:quinone oxidoreductase (PfNDH2).

  Journal of medicinal chemistry 20120308

• A physico-chemical and biological study of novel chitosan-chloroquinoline derivative for biomedical applications.

  International journal of biological macromolecules 20111001

• Effects of highly active novel artemisinin-chloroquinoline hybrid compounds on β-hematin formation, parasite morphology and endocytosis in Plasmodium falciparum.

  Biochemical pharmacology 20110801

• Antiprotozoal activity of chloroquinoline based chalcones.

  European journal of medicinal chemistry 20110501

• [Rationale for hygienic regulations for the use of a new mixed herbicide antidote].

  Gigiena i sanitariia 20110101

• N-[(2-Chloro-3-quinol-yl)meth-yl]-4-fluoro-aniline.

  Acta crystallographica. Section E, Structure reports online 20101001

• 1-{6-Chloro-2-[(2-chloro-8-methyl-3-quinol-yl)meth-oxy]-4-phenyl-quinolin-3-yl}ethanone.

  Acta crystallographica. Section E, Structure reports online 20100801

• 4-Chloro-2,5-dimethyl-quinoline.

  Acta crystallographica. Section E, Structure reports online 20100801

• 1-{6-Chloro-2-[(2-chloro-3-quinol-yl)meth-oxy]-4-phenyl-3-quinol-yl}ethan-1-one.

  Acta crystallographica. Section E, Structure reports online 20100701

• 1-{6-Chloro-2-[(2-chloro-6-methyl-quinolin-3-yl)meth-oxy]-4-phenyl-quinolin-3-yl}ethanone.

  Acta crystallographica. Section E, Structure reports online 20100701

• Synthesis and in vitro biological evaluation of carbon-11-labeled quinoline derivatives as new candidate PET radioligands for cannabinoid CB2 receptor imaging.

  Bioorganic & medicinal chemistry 20100315

• Chemoenzymatic synthesis of chiral 2,2'-bipyridine ligands and their N-oxide derivatives: applications in the asymmetric aminolysis of epoxides and asymmetric allylation of aldehydes.

  Organic & biomolecular chemistry 20100307

• The identification of nonpeptide neurotensin receptor partial agonists from the potent antagonist SR48692 using a calcium mobilization assay.

  Bioorganic & medicinal chemistry letters 20090301

• Chemicals possessing a neurotrophin-like activity on dopaminergic neurons in primary culture.

  PloS one 20090101

• Azaarene cis-dihydrodiol-derived 2,2'-bipyridine ligands for asymmetric allylic oxidation and cyclopropanation.

  Chemical communications (Cambridge, England) 20081121

• N-(2-Chloro-quinolin-3-ylmethyl-ene)aniline.

  Acta crystallographica. Section E, Structure reports online 20080101

• Sensitive and rapid liquid chromatography/tandem mass spectrometric assay for the quantification of piperaquine in human plasma.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20071101

• Sensitive and rapid liquid chromatography/tandem mass spectrometric assay for the quantification of chloroquine in dog plasma.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070601

• Chloroquinolines block antibiotic efflux pumps in antibiotic-resistant Enterobacter aerogenes isolates.

  International journal of antimicrobial agents 20060601

• Use of highly active palladium-phosphinous acid catalysts in Stille, Heck, amination, and thiation reactions of chloroquinolines.

  The Journal of organic chemistry 20030905

• Novel synthesis of 2-chloroquinolines from 2-vinylanilines in nitrile solvent.

  The Journal of organic chemistry 20021101

• Synthesis of 1,4-disubstituted 2-methylpiperazine derivatives, new 5-HT(1A) receptor ligands.

  Acta poloniae pharmaceutica 20010101