-
Effect of decursin on the pharmacokinetics of theophylline and its metabolites in rats.
Journal of ethnopharmacology 20121121
-
Comparison of N-acetyltransferase-2 enzyme genotype-phenotype and xanthine oxidase enzyme activity between Swedes and Koreans.
Journal of clinical pharmacology 20121001
-
Effect of decursinol angelate on the pharmacokinetics of theophylline and its metabolites in rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20121001
-
The methyl xanthine caffeine inhibits DNA damage signaling and reactive species and reduces atherosclerosis in ApoE(-/-) mice.
Arteriosclerosis, thrombosis, and vascular biology 20121001
-
Microvascular blood flow responses to muscle contraction are not altered by high-fat feeding in rats.
Diabetes, obesity & metabolism 20120801
-
The effects of xanthine oxidase inhibition by febuxostat on the pharmacokinetics of theophylline.
International journal of clinical pharmacology and therapeutics 20120501
-
Regulation of muscle microcirculation in health and diabetes.
Diabetes & metabolism journal 20120401
-
Development and validation of a sensitive LC-MS/MS method for the simultaneous quantitation of theophylline and its metabolites in rat plasma.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120315
-
cGMP phosphodiesterase inhibition improves the vascular and metabolic actions of insulin in skeletal muscle.
American journal of physiology. Endocrinology and metabolism 20110801
-
N-Acetyltransferase-2 (NAT2) gene polymorphisms and enzyme activity in Serbs: unprecedented high prevalence of rapid acetylators in a White population.
Journal of clinical pharmacology 20110701
-
Disposition kinetics of caffeine and paraxanthine in Nile tilapia (Oreochromis niloticus): characterization of the main metabolites.
Archives of environmental contamination and toxicology 20110501
-
Genistein alters caffeine exposure in healthy female volunteers.
European journal of clinical pharmacology 20110401
-
Loss of insulin-mediated microvascular perfusion in skeletal muscle is associated with the development of insulin resistance.
Diabetes, obesity & metabolism 20100901
-
Plant polyphenol curcumin significantly affects CYP1A2 and CYP2A6 activity in healthy, male Chinese volunteers.
The Annals of pharmacotherapy 20100601
-
Is 1-methylxanthine an ideal model substrate for establishing the renal tubular transport of organic ions?
International journal of clinical pharmacology and therapeutics 20100201
-
Demethylation of theophylline (1,3-dimethylxanthine) to 1-methylxanthine: the first step of an antioxidising cascade.
Redox report : communications in free radical research 20100101
-
Simultaneous action of the flavonoid quercetin on cytochrome P450 (CYP) 1A2, CYP2A6, N-acetyltransferase and xanthine oxidase activity in healthy volunteers.
Clinical and experimental pharmacology & physiology 20090801
-
Two distinct pathways for metabolism of theophylline and caffeine are coexpressed in Pseudomonas putida CBB5.
Journal of bacteriology 20090701
-
Enhancement of radiotherapeutic effectiveness by temperature-sensitive liposomal 1-methylxanthine.
International journal of pharmaceutics 20090508
-
Interleukin-6 attenuates insulin-mediated increases in endothelial cell signaling but augments skeletal muscle insulin action via differential effects on tumor necrosis factor-alpha expression.
Diabetes 20090501
-
Caffeine metabolic ratios for the in vivo evaluation of CYP1A2, N-acetyltransferase 2, xanthine oxidase and CYP2A6 enzymatic activities.
Current drug metabolism 20090501
-
Phenotyping of N-acetyltransferase type 2 and xanthine oxidase with caffeine: when should urine samples be collected?
European journal of clinical pharmacology 20090401
-
1-Methylxanthine enhances the radiosensitivity of tumor cells.
International journal of radiation biology 20090201
-
Relaxing and contracting effects of theophylline's metabolites on the rabbit upper gastrointestinal tract.
Fundamental & clinical pharmacology 20081001
-
Anti-inflammatory effect of theophylline in rats and its involvement of the glucocorticoid-glucocorticoid receptor system.
Journal of pharmacological sciences 20080401
-
Point: There is capillary recruitment in active skeletal muscle during exercise.
Journal of applied physiology (Bethesda, Md. : 1985) 20080301
-
[Recommended treatment of apnea in premature infants. A review based on literature and own experience].
Medycyna wieku rozwojowego 20080101
-
Inhibitory effects of caffeine and its metabolites on intracellular lipid accumulation in murine 3T3-L1 adipocytes.
BioFactors (Oxford, England) 20080101
-
Theophylline and its metabolites produce a stimulating cholinergic effect on the small intestine and a nonadrenergic noncholinergic relaxing effect on the colon: a comparative study in the rabbit intestine.
Journal of veterinary pharmacology and therapeutics 20071201
-
Reduction in non-glomerular renal clearance of the caffeine metabolite 1-methylxanthine by probenecid.
International journal of clinical pharmacology and therapeutics 20070801
-
The screening and characterization of 6-aminopurine-based xanthine oxidase inhibitors.
Bioorganic & medicinal chemistry 20070515
-
Acute effects of wortmannin on insulin's hemodynamic and metabolic actions in vivo.
American journal of physiology. Endocrinology and metabolism 20070301
-
Concordance between the deduced acetylation status generated by high-speed: real-time PCR based NAT2 genotyping of seven single nucleotide polymorphisms and human NAT2 phenotypes determined by a caffeine assay.
Clinica chimica acta; international journal of clinical chemistry 20070201
-
In vivo evaluation of CYP1A2, CYP2A6, NAT-2 and xanthine oxidase activities in a Greek population sample by the RP-HPLC monitoring of caffeine metabolic ratios.
Biomedical chromatography : BMC 20070201
-
Effect of diet on the development of drug metabolism by cytochrome P-450 enzymes in healthy infants.
Pediatric research 20061201
-
Caffeine N3-demethylation (CYP1A2) in a population with an increased exposure to polychlorinated biphenyls.
European journal of clinical pharmacology 20061201
-
Caffeine metabolites are inhibitors of the nuclear enzyme poly(ADP-ribose)polymerase-1 at physiological concentrations.
Biochemical pharmacology 20060928
-
Associations between CYP2E1 promoter polymorphisms and plasma 1,3-dimethyluric acid/theophylline ratios.
European journal of clinical pharmacology 20060801
-
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
-
[Determination of the activity of cytochrome P-450 CYP2A6 by HPLC method with caffeine as metabolizing probe].
Yao xue xue bao = Acta pharmaceutica Sinica 20060301
-
Kinetic analysis and modelling of the allosteric behaviour of liver and muscle glycogen phosphorylases.
Journal of molecular recognition : JMR 20060101
-
Re-investigation of the concordance of human NAT2 phenotypes and genotypes.
Archives of toxicology 20050401
-
Measurement of caffeine and five of the major metabolites in urine by high-performance liquid chromatography/tandem mass spectrometry.
Journal of mass spectrometry : JMS 20050301
-
Capillary electrochromatography of caffeine and its metabolites in rat brain microdialysate.
Electrophoresis 20050201
-
Exercise and insulin-mediated capillary recruitment in muscle.
Exercise and sport sciences reviews 20050101
-
Local methacholine but not bradykinin potentiates insulin-mediated glucose uptake in muscle in vivo by augmenting capillary recruitment.
Diabetologia 20041201
-
High-throughput liquid chromatography-tandem mass spectrometry assay for plasma theophylline and its metabolites.
Clinical chemistry 20041101
-
Skeletal muscle contraction stimulates capillary recruitment and glucose uptake in insulin-resistant obese Zucker rats.
American journal of physiology. Endocrinology and metabolism 20041001
-
Separation, pre-concentration, and HPLC analysis of methylxanthines in urine samples.
Journal of separation science 20041001
-
Inhibition of the human organic anion transporter 1 by the caffeine metabolite 1-methylxanthine.
Biochemical and biophysical research communications 20040716
-
Phenotyping of N-acetyltransferase type 2 by caffeine from uncontrolled dietary exposure.
European journal of clinical pharmacology 20040301
-
Insulin sensitivity of muscle capillary recruitment in vivo.
Diabetes 20040201
-
Cytochrome P450 1A2 (CYP1A2) activity, mammographic density, and oxidative stress: a cross-sectional study.
Breast cancer research : BCR 20040101
-
Cytochrome P450 1A2 (CYP1A2) activity and risk factors for breast cancer: a cross-sectional study.
Breast cancer research : BCR 20040101
-
Acetylator phenotyping in patients with malignant lymphomas, using caffeine as the metabolic probe.
Polish journal of pharmacology 20040101
-
T-1032, a cyclic GMP phosphodiesterase-5 inhibitor, acutely blocks physiologic insulin-mediated muscle haemodynamic effects and glucose uptake in vivo.
British journal of pharmacology 20031201
-
TNF-alpha acutely inhibits vascular effects of physiological but not high insulin or contraction.
American journal of physiology. Endocrinology and metabolism 20030901
-
Inhibiting NOS blocks microvascular recruitment and blunts muscle glucose uptake in response to insulin.
American journal of physiology. Endocrinology and metabolism 20030701
-
Preventive effect of zaprinast and 3-isobutyl, 1-methylxanthine (phosphodiesterase inhibitors) on gastric injury induced by nonsteroidal antiinflammatory drugs in rats.
Digestive diseases and sciences 20030501
-
Nonnutritive flow impairs uptake of fatty acid by white muscles of the perfused rat hindlimb.
American journal of physiology. Endocrinology and metabolism 20030301
-
Interaction of ibuprofen and probenecid with drug metabolizing enzyme phenotyping procedures using caffeine as the probe drug.
British journal of clinical pharmacology 20030201
-
Pharmacokinetics of intravenous theophylline in mutant Nagase analbuminemic rats.
Life sciences 20030131
-
Insulin-mediated hemodynamic changes are impaired in muscle of Zucker obese rats.
Diabetes 20021201
-
Effects of acute renal failure induced by uranyl nitrate on the pharmacokinetics of intravenous theophylline in rats: the role of CYP2E1 induction in 1,3-dimethyluric acid formation.
The Journal of pharmacy and pharmacology 20021201
-
Severe 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) intoxication: insights into the measurement of hepatic cytochrome P450 1A2 induction.
Clinical pharmacology and therapeutics 20020801
-
Differences in caffeine and paraxanthine metabolism between human and murine CYP1A2.
Biochemical pharmacology 20020615
-
Lipid infusion impairs physiologic insulin-mediated capillary recruitment and muscle glucose uptake in vivo.
Diabetes 20020401
-
Autocrine and paracrine regulation of lymphocyte CB2 receptor expression by TGF-beta.
Biochemical and biophysical research communications 20020111
-
Skeletal muscle microvascular recruitment by physiological hyperinsulinemia precedes increases in total blood flow.
Diabetes 20020101
-
Group I aptazymes as genetic regulatory switches.
BMC biotechnology 20020101
-
Structural basis for the binding affinity of xanthines with the DNA intercalator acridine orange.
Journal of medicinal chemistry 20011220
-
Exercise training improves insulin-mediated capillary recruitment in association with glucose uptake in rat hindlimb.
Diabetes 20011201
-
Physiologic hyperinsulinemia enhances human skeletal muscle perfusion by capillary recruitment.
Diabetes 20011201
-
Urinary biomarkers for assessing dietary exposure to caffeine.
Food additives and contaminants 20011201
-
Use of novel solid-phase extraction sorbent materials for high-performance liquid chromatography quantitation of caffeine metabolism products methylxanthines and methyluric acids in samples of biological origin.
Journal of chromatography. B, Biomedical sciences and applications 20010815
-
The effect of pregnancy on cytochrome P4501A2, xanthine oxidase, and N-acetyltransferase activities in humans.
Clinical pharmacology and therapeutics 20010801
-
Validity of an ELISA for N-acetyltransferase-2 (NAT2) phenotyping.
Journal of immunological methods 20010501
-
Inhibition of human CYP1A2 activity in vitro by methylxanthines: potent competitive inhibition by 8-phenyltheophylline.
Xenobiotica; the fate of foreign compounds in biological systems 20010301
-
Determination of urinary methylated purine pattern by high-performance liquid chromatography.
Journal of chromatography. B, Biomedical sciences and applications 20010210
-
Caffeine metabolism before and after liver transplantation.
International journal of clinical pharmacology and therapeutics 20010201
-
Caffeine metabolism in a group of 67 patients with primary biliary cirrhosis.
International journal of clinical pharmacology and therapeutics 20010101
-
Xanthine oxidase activity and blood glutathione redox ratio in infants and children with septic shock syndrome.
Intensive care medicine 20010101
-
[The acetylator polymorphism in a Khmer population: clinical consequences].
Therapie 20010101
-
Neurotoxic convulsions induced by theophylline and its metabolites in mice.
Biological & pharmaceutical bulletin 19960601
-
Structure-activity relationships for the binding of ligands to xanthine or guanine phosphoribosyl-transferase from Toxoplasma gondii.
Biochemical pharmacology 19951109
-
Synthesis and structure-activity relationships of deazaxanthines: analogs of potent A1- and A2-adenosine receptor antagonists.
Journal of medicinal chemistry 19940513
-
Enhancement of acute myocardial lesions by asthma drugs in rats.
Toxicologic pathology 19940101
-
Synthesis of paraxanthine analogs (1,7-disubstituted xanthines) and other xanthines unsubstituted at the 3-position: structure-activity relationships at adenosine receptors.
Journal of medicinal chemistry 19931029
