6146-52-7 | 5-Nitroindole

Packsize	Purity	Availability	Price	Discounted Price
5g	95%	in stock	$13.00	$9.00
10g	95%	in stock	$21.00	$15.00
25g	95%	in stock	$29.00	$20.00
500g	95%	in stock	$541.00	$379.00

Description

• Catalog Number: AB69478
• Chemical Name: 5-Nitroindole
• CAS Number: 6146-52-7
• Molecular Formula: C8H6N2O2
• Molecular Weight: 162.1454
• MDL Number: MFCD00005673
• SMILES: O=N(=O)c1ccc2c(c1)cc[nH]2
• NSC Number: 520594

Computed Properties

• Complexity: 190
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 12
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 1
• XLogP3: 2.5

Literature

• Modification of the siRNA passenger strand by 5-nitroindole dramatically reduces its off-target effects.

  Chembiochem : a European journal of chemical biology 20120903

• Modulation of imprinting efficiency in nanogels with catalytic activity in the Kemp elimination.

  Journal of molecular recognition : JMR 20120601

• Thermodynamic Control of Small RNA-Mediated Gene Silencing.

  Frontiers in genetics 20120101

• Integrated NMR and computational study of push-pull NLO probes: interplay of solvent and structural effects.

  The journal of physical chemistry. A 20110908

• A multi-step process of viral adaptation to a mutagenic nucleoside analogue by modulation of transition types leads to extinction-escape.

  PLoS pathogens 20100801

• Cationic nucleoside lipids derived from universal bases: A rational approach for siRNA transfection.

  Bioconjugate chemistry 20100616

• Replication of a universal nucleobase provides unique insight into the role of entropy during DNA polymerization and pyrophosphorolysis.

  Biochemistry 20100413

• Template-directed ligation of tethered mononucleotides by t4 DNA ligase for kinase ribozyme selection.

  PloS one 20100101

• Potential benefits of sequential inhibitor-mutagen treatments of RNA virus infections.

  PLoS pathogens 20091101

• Evolving a polymerase for hydrophobic base analogues.

  Journal of the American Chemical Society 20091021

• Primer fabrication using polymerase mediated oligonucleotide synthesis.

  BMC genomics 20090101

• Thiazole orange and Cy3: improvement of fluorescent DNA probes with use of short range electron transfer.

  The Journal of organic chemistry 20080606

• [Oligodeoxynucleotides containing substituted 4-nitroindoles: synthesis and study of their DNA duplexes].

  Bioorganicheskaia khimiia 20080101

• Synthesis of a universal 5-nitroindole ribonucleotide and incorporation into RNA by a viral RNA-dependent RNA polymerase.

  Chembiochem : a European journal of chemical biology 20070813

• [Spectral analysis of the effect of different polymerization potential on electrosynthesized poly (5-nitroindole) films].

  Guang pu xue yu guang pu fen xi = Guang pu 20070601

• Solution structure and dynamics of DNA duplexes containing the universal base analogues 5-nitroindole and 5-nitroindole 3-carboxamide.

  Nucleic acids research 20070501

• Analysis of multiple single nucleotide polymorphisms closely positioned in the ovine PRNP gene using linear fluorescent probes and melting curve analysis.

  BMC infectious diseases 20070101

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• 1H NMR spectral studies on the polymerization mechanism of indole and its derivatives.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20060301

• Large fragment Bst DNA polymerase for whole genome amplification of DNA from formalin-fixed paraffin-embedded tissues.

  BMC genomics 20060101

• Novel anellated pyrazoloquinolin-3-ones: synthesis and in vitro BZR activity.

  Bioorganic & medicinal chemistry 20050516

• Generic expansion of the substrate spectrum of a DNA polymerase by directed evolution.

  Nature biotechnology 20040601

• Facile polymerization of dNTPs bearing unnatural base analogues by DNA polymerase alpha and Klenow fragment (DNA polymerase I).

  Biochemistry 20030909

• Method for detection of single-base mismatches using bimolecular beacons.

  Journal of the American Chemical Society 20020320

• [Enhancing the stability of oligonucleotide duplexes. The effect of adding 1-(2'-deoxy-beta-d-ribofuranosyl)-5-nitroindole].

  Molekuliarnaia biologiia 20020101

• An efficient conversion of 5-nitroisatin into 5-nitroindole derivative.

  Bioorganic & medicinal chemistry letters 20010326