619-42-1 | Methyl 4-bromobenzoate

Packsize	Purity	Availability	Price	Discounted Price
10g	98%	in stock	$5.00	$4.00
25g	98%	in stock	$6.00	$5.00
100g	98%	in stock	$14.00	$10.00
500g	98%	in stock	$70.00	$49.00

Description

• Catalog Number: AB46514
• Chemical Name: Methyl 4-bromobenzoate
• CAS Number: 619-42-1
• Molecular Formula: C8H7BrO2
• Molecular Weight: 215.044
• MDL Number: MFCD00013531
• SMILES: COC(=O)c1ccc(cc1)Br
• NSC Number: 9392

Computed Properties

• Complexity: 139
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• XLogP3: 3

Upstream Synthesis Route

Methyl 4-Bromobenzoate is a versatile compound commonly used in chemical synthesis due to its reactivity and structural properties. With a molecular formula of C8H7BrO2, this organic ester plays a crucial role in various synthetic processes.One of the primary applications of Methyl 4-Bromobenzoate in chemical synthesis is its involvement in esterification reactions. By reacting this compound with alcohols in the presence of an acid catalyst, esters with diverse functional groups can be easily synthesized. These esters find extensive use in the fragrance, flavor, and pharmaceutical industries, contributing to the production of various consumer products.Furthermore, Methyl 4-Bromobenzoate serves as a precursor in the preparation of biologically active compounds and pharmaceutical intermediates. Its bromine functional group allows for further derivatization, enabling the synthesis of complex molecules with specific biological activities. This compound's versatility makes it a valuable building block in the creation of medicinally important compounds.In addition to its role in esterification and pharmaceutical synthesis, Methyl 4-Bromobenzoate can also participate in cross-coupling reactions and other transformations, leading to the formation of novel molecular architectures. Its ability to undergo diverse chemical reactions makes it a valuable tool for organic chemists engaged in the discovery and development of new compounds with unique properties.

Literature

• Synthesis of classical, three-carbon-bridged 5-substituted furo[2,3-d]pyrimidine and 6-substituted pyrrolo[2,3-d]pyrimidine analogues as antifolates.

  Journal of medicinal chemistry 20041230