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The mixture of 'ecstasy' and its metabolites is toxic to human SH-SY5Y differentiated cells at in vivo relevant concentrations.
Archives of toxicology 20140201
-
Effects of MDMA (ecstasy) and two of its metabolites on rat embryos in vitro.
Reproductive toxicology (Elmsford, N.Y.) 20120801
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Radiosynthesis of carbon-11 labeled 6-methyldopamine ([¹¹C]MeDA).
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20120801
-
A convenient biomimetic synthesis of optically active putative neurotoxic metabolites of MDMA ('ecstasy') from R-(-)- and S-(+)-N-methyl-α-methyldopamine precursors.
Organic & biomolecular chemistry 20120514
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Six months treatment with ibopamine in patients with hypotony after vitreoretinal surgery for retinal detachment, uveitis or penetrating trauma.
Retina (Philadelphia, Pa.) 20120401
-
Pro-oxidant effects of Ecstasy and its metabolites in mouse brain synaptosomes.
British journal of pharmacology 20120201
-
A novel G protein-coupled receptor of Schistosoma mansoni (SmGPR-3) is activated by dopamine and is widely expressed in the nervous system.
PLoS neglected tropical diseases 20120201
-
Induction of glutathione synthesis and conjugation by 3,4-methylenedioxymethamphetamine (MDMA) and 3,4-dihydroxymethamphetamine (HHMA) in human and rat liver cells, including the protective role of some antioxidants.
Toxicology 20111118
-
Inhibition of 3,4-methylenedioxymethamphetamine metabolism leads to marked decrease in 3,4-dihydroxymethamphetamine formation but no change in serotonin neurotoxicity: implications for mechanisms of neurotoxicity.
Synapse (New York, N.Y.) 20111001
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Development and validation of LC-HRMS and GC-NICI-MS methods for stereoselective determination of MDMA and its phase I and II metabolites in human urine.
Journal of mass spectrometry : JMS 20110701
-
Chiral capillary electrophoresis-mass spectrometry of tetrahydroisoquinoline-derived neurotoxins: observation of complex stereoisomerism.
Journal of chromatography. A 20110520
-
Comparative neurochemical profile of 3,4-methylenedioxymethamphetamine and its metabolite alpha-methyldopamine on key targets of MDMA neurotoxicity.
Neurochemistry international 20110101
-
Kinetic cooperativity of tyrosinase. A general mechanism.
Acta biochimica Polonica 20110101
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Pigmented deposits on a Boston keratoprosthesis from topical ibopamine.
Cornea 20100901
-
Efficacy of 2% ibopamine on the dilation of patients with pseudoexfoliation syndrome.
European journal of ophthalmology 20100101
-
Synthesis and in vitro cytotoxicity profile of the R-enantiomer of 3,4-dihydroxymethamphetamine (R-(-)-HHMA): comparison with related catecholamines.
Chemical research in toxicology 20100101
-
The mydriatic effect of intracameral epinine hydrochloride.
Investigative ophthalmology & visual science 20091101
-
Further studies on the role of metabolites in (+/-)-3,4-methylenedioxymethamphetamine-induced serotonergic neurotoxicity.
Drug metabolism and disposition: the biological fate of chemicals 20091001
-
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Nature chemical biology 20091001
-
Concerted action of the cytosolic sulfotransferase, SULT1A3, and catechol-O-methyltransferase in the metabolism of dopamine in SK-N-MC human neuroblastoma cells.
Neuroscience research 20090701
-
Hydrolysis of 3,4-methylenedioxymethamphetamine (MDMA) metabolite conjugates in human, squirrel monkey, and rat plasma.
Analytical and bioanalytical chemistry 20090301
-
[Metabolites of ecstasy and cytotoxicity effects].
Annales pharmaceutiques francaises 20090301
-
Metabolites of MDMA induce oxidative stress and contractile dysfunction in adult rat left ventricular myocytes.
Cardiovascular toxicology 20090301
-
Simultaneous liquid chromatographic-electrospray ionization mass spectrometric quantification of 3,4-methylenedioxymethamphetamine (MDMA, Ecstasy) and its metabolites 3,4-dihydroxymethamphetamine, 4-hydroxy-3-methoxymethamphetamine and 3,4-methylenedioxyamphetamine in squirrel monkey and human plasma after acidic conjugate cleavage.
Forensic science international 20090130
-
Low pulse pressure is an independent predictor of mortality and morbidity in non ischaemic, but not in ischaemic advanced heart failure patients.
International journal of cardiology 20090124
-
Cross-functioning between the extraneuronal monoamine transporter and multidrug resistance protein 1 in the uptake of adrenaline and export of 5-(glutathion-S-yl)adrenaline in rat cardiomyocytes.
Chemical research in toxicology 20090101
-
[Effects of 2% ibopamine eye drops on the results of computerized visual field].
Arquivos brasileiros de oftalmologia 20090101
-
Liquid chromatographic-electrospray ionization mass spectrometric assay for simultaneous determination of 3,4-methylenedioxymethamphetamine and its metabolites 3,4-methylenedioxyamphetamine, 3,4-dihydroxymethamphetamine, and 4-hydroxy-3-methoxymethamphetamine in rat brain.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20081015
-
Nonlinear pharmacokinetics of (+/-)3,4-methylenedioxymethamphetamine (MDMA, 'Ecstasy') and its major metabolites in squirrel monkeys at plasma concentrations of MDMA that develop after typical psychoactive doses.
The Journal of pharmacology and experimental therapeutics 20081001
-
[2% ibopamine vs. water-drinking test as a provocative test for glaucoma].
Arquivos brasileiros de oftalmologia 20080101
-
Effect of methyl derivatives of dopamine on tumor necrosis factor alpha and lipid peroxidation.
Annals of the New York Academy of Sciences 20071201
-
3-O-methyldopamine (3-O-methoxytyramine) interferes with the internal standard 3,4-dihydroxybenzylamine in a plasma catecholamine HPLC method.
Clinical chemistry 20071101
-
Ambient temperature effects on 3,4-methylenedioxymethamphetamine-induced thermodysregulation and pharmacokinetics in male monkeys.
Drug metabolism and disposition: the biological fate of chemicals 20071001
-
Validated liquid chromatographic-electrospray ionization mass spectrometric assay for simultaneous determination of 3,4-methylenedioxymethamphetamine and its metabolites 3,4-methylenedioxyamphetamine, 3,4-dihydroxymethamphetamine, and 4-hydroxy-3-methoxymethamphetamine in squirrel monkey plasma.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070815
-
Neurotoxicity mechanisms of thioether ecstasy metabolites.
Neuroscience 20070608
-
[Positive ibopamine provocative test in normal-tension glaucoma suspects].
Klinische Monatsblatter fur Augenheilkunde 20070401
-
Influence of CYP2D6 polymorphism on 3,4-methylenedioxymethamphetamine ('Ecstasy') cytotoxicity.
Pharmacogenetics and genomics 20061101
-
A new approach for treatment of hypertension: modifying D1 dopamine receptor function.
Cardiovascular & hematological agents in medicinal chemistry 20061001
-
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
-
[Treatment of uveitis-associated refractory ocular hypotony with topical ibopamine].
Klinische Monatsblatter fur Augenheilkunde 20060501
-
Topical ibopamine in the treatment of chronic ocular hypotony attributable to vitreoretinal surgery, uveitis, or penetrating trauma.
American journal of ophthalmology 20060301
-
[Prostaglandin analogues reduce the ibopamine provocative test specificity in glaucoma].
Arquivos brasileiros de oftalmologia 20060101
-
Correlation between the ibopamine provocative test and the diurnal tension curve in glaucoma patients.
Arquivos brasileiros de oftalmologia 20060101
-
Comparison between the 1% and 2% ibopamine provocative test in primary open-angle glaucoma patients: sensitivity, specificity and tolerability.
Arquivos brasileiros de oftalmologia 20060101
-
The comparison of topical ibopamine 2% with tonography to identify the outflow resistance in eyes with ocular hypertension.
Ophthalmic research 20050101
-
A comparative study on the acute and long-term effects of MDMA and 3,4-dihydroxymethamphetamine (HHMA) on brain monoamine levels after i.p. or striatal administration in mice.
British journal of pharmacology 20050101
-
Stereochemical analysis of 3,4-methylenedioxymethamphetamine and its main metabolites in human samples including the catechol-type metabolite (3,4-dihydroxymethamphetamine).
Drug metabolism and disposition: the biological fate of chemicals 20040901
-
The toxicity of N-methyl-alpha-methyldopamine to freshly isolated rat hepatocytes is prevented by ascorbic acid and N-acetylcysteine.
Toxicology 20040805
-
Metabolism is required for the expression of ecstasy-induced cardiotoxicity in vitro.
Chemical research in toxicology 20040501
-
Ibopamine provocative test and glaucoma: consideration of factors that may influence the examination.
Current eye research 20040301
-
Hepatotoxicity of 3,4-methylenedioxyamphetamine and alpha-methyldopamine in isolated rat hepatocytes: formation of glutathione conjugates.
Archives of toxicology 20040101
-
The effects of 2% ibopamine eye drops on the intraocular pressure and pupil motility of patients with open-angle glaucoma.
European journal of ophthalmology 20040101
-
Effect of ibopamine on aqueous humor production in normotensive humans.
Investigative ophthalmology & visual science 20031101
-
Synthesis, in vitro formation, and behavioural effects of glutathione regioisomers of alpha-methyldopamine with relevance to MDA and MDMA (ecstasy).
Brain research 20031017
-
Apparent heterogeneous responsiveness of human platelet rich plasma to catecholamines.
Platelets 20030501
-
Effects of ibopamine eye drops on intraocular pressure and aqueous humor flow in healthy volunteers and patients with open-angle glaucoma.
European journal of ophthalmology 20030501
-
Comparative study of the effects of 2% ibopamine, 10% phenylephrine, and 1% tropicamide on the anterior segment.
Investigative ophthalmology & visual science 20030101
-
High-performance liquid chromatography with electrochemical detection applied to the analysis of 3,4-dihydroxymethamphetamine in human plasma and urine.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020405
-
Synthesis and capillary electrophoretic analysis of enantiomerically enriched reference standards of MDMA and its main metabolites.
Bioorganic & medicinal chemistry 20020401
-
Determination of MDMA and its metabolites in blood and urine by gas chromatography-mass spectrometry and analysis of enantiomers by capillary electrophoresis.
Journal of analytical toxicology 20020401
-
Ibopamine test and frequency doubling perimetry in early glaucoma diagnosis.
Acta ophthalmologica Scandinavica. Supplement 20020101
-
3,4-Dihydroxymethamphetamine (HHMA). A major in vivo 3,4-methylenedioxymethamphetamine (MDMA) metabolite in humans.
Chemical research in toxicology 20010901
-
Treatment of severe ocular hypotony in AIDS patients with cytomegalovirus retinitis and cidofovir-associated uveitis.
Ocular immunology and inflammation 20010901
-
Treatment of severe ocular hypotony in AIDS patients with cytomegalovirus retinitis and cidofovir-associated uveitis.
Ocular immunology and inflammation 20010901
-
The underreporting of results and possible mechanisms of 'negative' drug trials in patients with chronic heart failure.
International journal of cardiology 20010801
-
Effects of 2% ibopamine on pupil, refraction, anterior segment anatomy and intraocular pressure.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20010601
-
Confounding by contraindication in a nationwide cohort study of risk for death in patients taking ibopamine.
Annals of internal medicine 20010403
-
Serotonergic neurotoxicity of methylenedioxyamphetamine and methylenedioxymetamphetamine.
Advances in experimental medicine and biology 20010101
-
The neurotoxic effects of methylenedioxymethamphetamine (MDMA) and its metabolites on rat brain spheroids in culture.
Cell biology and toxicology 19990601
-
Dose-dependent separation of dopaminergic and adrenergic effects of epinine in healthy volunteers.
Naunyn-Schmiedeberg's archives of pharmacology 19951001
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[Asymptomatic autoimmune hemolysis linked to alpha-methyldopa. Importance of the study of erythrocyte survival in vivo].
Revue francaise de transfusion et immuno-hematologie 19820601
