621-54-5 | 3-(3-Hydroxyphenyl)propionic acid

Packsize	Purity	Availability	Price	Discounted Price
1g	95%	in stock	$13.00	$9.00
5g	95%	in stock	$34.00	$24.00
25g	95%	in stock	$108.00	$76.00
100g	95%	in stock	$375.00	$262.00

Description

• Catalog Number: AB44245
• Chemical Name: 3-(3-Hydroxyphenyl)propionic acid
• CAS Number: 621-54-5
• Molecular Formula: C9H10O3
• Molecular Weight: 166.1739
• MDL Number: MFCD00016554
• SMILES: OC(=O)CCc1cccc(c1)O

Computed Properties

• Complexity: 156
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 12
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 3
• XLogP3: 1.4

Literature

• Impact of short-term intake of red wine and grape polyphenol extract on the human metabolome.

  Journal of agricultural and food chemistry 20120328

• F420H2-dependent degradation of aflatoxin and other furanocoumarins is widespread throughout the actinomycetales.

  PloS one 20120101

• Metabolomic applications to decipher gut microbial metabolic influence in health and disease.

  Frontiers in physiology 20120101

• In vitro bioaccessibility and gut biotransformation of polyphenols present in the water-insoluble cocoa fraction.

  Molecular nutrition & food research 20110501

• Comparative genomics and functional analysis of niche-specific adaptation in Pseudomonas putida.

  FEMS microbiology reviews 20110301

• The mind-body-microbial continuum.

  Dialogues in clinical neuroscience 20110301

• Escherichia coli mhpR gene expression is regulated by catabolite repression mediated by the cAMP-CRP complex.

  Microbiology (Reading, England) 20110201

• Global metabolic phenotyping in an experimental laparotomy model of surgical trauma.

  Journal of proteome research 20110107

• Antioxidative protection of dietary bilberry, chokeberry and Lactobacillus plantarum HEAL19 in mice subjected to intestinal oxidative stress by ischemia-reperfusion.

  BMC complementary and alternative medicine 20110101

• The homogentisate and homoprotocatechuate central pathways are involved in 3- and 4-hydroxyphenylacetate degradation by Burkholderia xenovorans LB400.

  PloS one 20110101

• Screening of an E. coli O157:H7 Bacterial Artificial Chromosome Library by Comparative Genomic Hybridization to Identify Genomic Regions Contributing to Growth in Bovine Gastrointestinal Mucus and Epithelial Cell Colonization.

  Frontiers in microbiology 20110101

• Colonic metabolites of berry polyphenols: the missing link to biological activity?

  The British journal of nutrition 20101001

• Proanthocyanidin metabolites associated with dietary fibre from in vitro colonic fermentation and proanthocyanidin metabolites in human plasma.

  Molecular nutrition & food research 20100701

• A comparison of the in vitro biotransformation of (-)-epicatechin and procyanidin B2 by human faecal microbiota.

  Molecular nutrition & food research 20100601

• Metabolic alterations in the hamster co-infected with Schistosoma japonicum and Necator americanus.

  International journal for parasitology 20100501

• Urinary excretion of phenolic acids in rats fed cranberry.

  Journal of agricultural and food chemistry 20100414

• Bioavailability of various polyphenols from a diet containing moderate amounts of berries.

  Journal of agricultural and food chemistry 20100414

• Flavanols and anthocyanins in cardiovascular health: a review of current evidence.

  International journal of molecular sciences 20100101

• 3-Hydroxyphenylpropionate and phenylpropionate are synergistic activators of the MhpR transcriptional regulator from Escherichia coli.

  The Journal of biological chemistry 20090807

• Bioprocessing of wheat bran improves in vitro bioaccessibility and colonic metabolism of phenolic compounds.

  Journal of agricultural and food chemistry 20090722

• Dihydroxylated phenolic acids derived from microbial metabolism reduce lipopolysaccharide-stimulated cytokine secretion by human peripheral blood mononuclear cells.

  The British journal of nutrition 20090701

• Procyanidin dimers are metabolized by human microbiota with 2-(3,4-dihydroxyphenyl)acetic acid and 5-(3,4-dihydroxyphenyl)-gamma-valerolactone as the major metabolites.

  Journal of agricultural and food chemistry 20090211

• Metabolic analysis of the soil microbe Dechloromonas aromatica str. RCB: indications of a surprisingly complex life-style and cryptic anaerobic pathways for aromatic degradation.

  BMC genomics 20090101

• Exploiting the pathway structure of metabolism to reveal high-order epistasis.

  BMC systems biology 20080101

• MFS transportome of the human pathogenic yeast Candida albicans.

  BMC genomics 20080101

• Characterization of the maduropeptin biosynthetic gene cluster from Actinomadura madurae ATCC 39144 supporting a unifying paradigm for enediyne biosynthesis.

  Journal of the American Chemical Society 20071031

• Sorghum bran in the diet dose dependently increased the excretion of catechins and microbial-derived phenolic acids in female rats.

  Journal of agricultural and food chemistry 20070627

• Weakening of salmonella with selected microbial metabolites of berry-derived phenolic compounds and organic acids.

  Journal of agricultural and food chemistry 20070516

• Coupled expression of MhpE aldolase and MhpF dehydrogenase in Escherichia coli.

  Biochemical and biophysical research communications 20060804

• Use of the pig caecum model to mimic the human intestinal metabolism of hispidulin and related compounds.

  Molecular nutrition & food research 20060101

• Sexual dimorphism in urinary metabolite profiles of Han Wistar rats revealed by nuclear-magnetic-resonance-based metabonomics.

  Analytical biochemistry 20050815

• Statistical total correlation spectroscopy: an exploratory approach for latent biomarker identification from metabolic 1H NMR data sets.

  Analytical chemistry 20050301

• Microbial metabolites of ingested caffeic acid are absorbed by the monocarboxylic acid transporter (MCT) in intestinal Caco-2 cell monolayers.

  Journal of agricultural and food chemistry 20041020

• The pig caecum model: a suitable tool to study the intestinal metabolism of flavonoids.

  Molecular nutrition & food research 20040901

• Supplementation with grape seed polyphenols results in increased urinary excretion of 3-hydroxyphenylpropionic Acid, an important metabolite of proanthocyanidins in humans.

  Journal of agricultural and food chemistry 20040825

• Transepithelial transport of chlorogenic acid, caffeic acid, and their colonic metabolites in intestinal caco-2 cell monolayers.

  Journal of agricultural and food chemistry 20040505

• Colonic metabolism of dietary polyphenols: influence of structure on microbial fermentation products.

  Free radical biology & medicine 20040115

• Identification of metabolites of (-)-epicatechin gallate and their metabolic fate in the rat.

  Journal of agricultural and food chemistry 20030827

• Regulation of the mhp cluster responsible for 3-(3-hydroxyphenyl)propionic acid degradation in Escherichia coli.

  The Journal of biological chemistry 20030725

• Inhibitory effects of urinary metabolites on platelet aggregation after orally administering Shimotsu-To, a traditional Chinese medicine, to rats.

  The Journal of pharmacy and pharmacology 20030201

• The relative toxicity of substituted phenols reported in cigarette mainstream smoke.

  Toxicological sciences : an official journal of the Society of Toxicology 20020901

• Effect of intestinal microflora on the urinary metabolic profile of rats: a (1)H-nuclear magnetic resonance spectroscopy study.

  Xenobiotica; the fate of foreign compounds in biological systems 20020901

• A novel Streptomyces gene, samR, with different effects on differentiation of Streptomyces ansochromogenes and Streptomyces coelicolor.

  Archives of microbiology 20020301

• Directly coupled high-performance liquid chromatography and nuclear magnetic resonance spectroscopic with chemometric studies on metabolic variation in Sprague--Dawley rats.

  Analytical biochemistry 20010415

• Electrospray ionisation mass spectrometric study of degradation products of quercetin, quercetin-3-glucoside and quercetin-3-rhamnoglucoside, produced by in vitro fermentation with human faecal flora.

  Rapid communications in mass spectrometry : RCM 20010101

• Genetic characterization and expression in heterologous hosts of the 3-(3-hydroxyphenyl)propionate catabolic pathway of Escherichia coli K-12.

  Journal of bacteriology 19970401