622-30-0 | N-Benzylhydroxylamine

Packsize	Purity	Availability	Price	Discounted Price
1g	96%	in stock	$68.00	$48.00
5g	96%	in stock	$201.00	$141.00
10g	96%	in stock	$322.00	$225.00
25g	96%	in stock	$626.00	$439.00
100g	96%	in stock	$1,691.00	$1,184.00

Description

• Catalog Number: AB50904
• Chemical Name: N-Benzylhydroxylamine
• CAS Number: 622-30-0
• Molecular Formula: C7H9NO
• Molecular Weight: 123.1525
• MDL Number: MFCD06654467
• SMILES: ONCc1ccccc1

Computed Properties

• Complexity: 69.3
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 9
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 2
• XLogP3: 1

Upstream Synthesis Route

N-Benzylhydroxylamine is a versatile compound commonly used in chemical synthesis as a reagent for specifically targeting carbonyl compounds. This compound is particularly useful in the field of organic chemistry due to its ability to act as a nucleophile towards various carbonyl-containing functional groups.By reacting with aldehydes and ketones, N-Benzylhydroxylamine can undergo selective condensation reactions to form oximes. These oximes can then be further manipulated through various transformations, such as Beckmann rearrangements, to synthesize a wide range of valuable organic compounds including pharmaceuticals, agrochemicals, and fine chemicals.Furthermore, N-Benzylhydroxylamine is an essential building block in the preparation of heterocycles and diverse nitrogen-containing structures. Its role in chemical synthesis extends to the formation of key intermediates in the production of specialty chemicals and complex organic molecules.In summary, N-Benzylhydroxylamine serves as a valuable tool in chemical synthesis, offering chemists a versatile and efficient means to introduce functional groups and generate structurally complex compounds in a controlled and selective manner.

Literature

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  Journal of the American Chemical Society 20121010

• NBHA reduces acrolein-induced changes in ARPE-19 cells: possible involvement of TGFβ.

  Current eye research 20110401

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  Acta crystallographica. Section E, Structure reports online 20100301

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  The Journal of organic chemistry 20100205

• Acrolein toxicity: Comparison with reactive oxygen species.

  Biochemical and biophysical research communications 20090109

• N-benzyl aspartate nitrones: unprecedented single-step synthesis and [3 + 2] cycloaddition reactions with alkenes.

  Organic letters 20081016

• A practical synthesis of (3R,4R)-N-tert-butoxycarbonyl-4-hydroxymethylpyrrolidin-3-ol.

  Organic & biomolecular chemistry 20070907

• Highly efficient three-component synthesis of beta-lactams from N-methylhydroxylamine, aldehydes, and phenylacetylene.

  Chemistry, an Asian journal 20060717

• Neurotoxicity of reactive aldehydes: the concept of 'aldehyde load' as demonstrated by neuroprotection with hydroxylamines.

  Brain research 20060620

• Cyclopropylamine inactivation of cytochromes P450: role of metabolic intermediate complexes.

  Archives of biochemistry and biophysics 20050415

• Enantioselective synthesis of alpha,beta-disubstituted-beta-amino acids.

  Journal of the American Chemical Society 20031001