623-49-4 | Ethyl cyanoformate

Packsize	Purity	Availability	Price	Discounted Price
5g	95%	in stock	$6.00	$5.00
25g	95%	in stock	$17.00	$12.00
100g	95%	in stock	$51.00	$36.00

Description

• Catalog Number: AB46103
• Chemical Name: Ethyl cyanoformate
• CAS Number: 623-49-4
• Molecular Formula: C4H5NO2
• Molecular Weight: 99.088
• MDL Number: MFCD00001836
• SMILES: CCOC(=O)C#N
• NSC Number: 65347

Computed Properties

• Complexity: 110
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 7
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• XLogP3: 0.6

Literature

• A highly enantioselective catalytic Strecker reaction of cyclic (Z)-aldimines.

  Chemical communications (Cambridge, England) 20120518

• C2-symmetric recyclable organocatalyst for enantioselective Strecker reaction for the synthesis of α-amino acid and chiral diamine--an intermediate for APN inhibitor.

  The Journal of organic chemistry 20120504

• Enantioselective trapping of an α-chiral carbanion of acyclic nitrile by a carbon electrophile.

  Chemical communications (Cambridge, England) 20120318

• Asymmetric cyanation of activated olefins with ethyl cyanoformate catalyzed by a modular titanium catalyst.

  Organic letters 20100319

• Enantioselective cyanoformylation of aldehydes catalyzed with solid base mediated chiral V(V) salen complexes.

  Chirality 20100101

• Asymmetric cyanation of aldehydes, ketones, aldimines, and ketimines catalyzed by a versatile catalyst generated from cinchona alkaloid, achiral substituted 2,2'-biphenol and tetraisopropyl titanate.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20091102

• Dual-activation asymmetric strecker reaction of aldimines and ketimines catalyzed by a tethered bis(8-quinolinolato) aluminum complex.

  Journal of the American Chemical Society 20091028

• Conformer lifetimes of ethyl cyanoformate from exchange-averaged rotational spectra.

  The journal of physical chemistry. A 20090625

• Cyanide ion promoted addition of acyl phosphonates to ethyl cyanoformate: synthesis of tertiary carbinols via tandem carbon-carbon bond formations.

  The Journal of organic chemistry 20070914

• Synthesis of alpha-keto esters by the rhodium-catalysed reaction of cyanoformate with arylboronic acids.

  Chemical communications (Cambridge, England) 20070719

• Evidence of conformational exchange averaging in the thermal rotational spectrum of ethyl cyanoformate.

  The journal of physical chemistry. A 20060615

• Synthesis, structure and reactivity of 5-pyranosyl-1,3,4-oxathiazol-2-ones.

  Carbohydrate research 20060116

• Dual Lewis acid-Lewis base activation in enantioselective cyanation of aldehydes using acetyl cyanide and cyanoformate as cyanide sources.

  Journal of the American Chemical Society 20050824

• Catalytic asymmetric cyano-ethoxycarbonylation reaction of aldehydes using a YLi3 tris(binaphthoxide) (YLB) complex: mechanism and roles of achiral additives.

  Journal of the American Chemical Society 20050316

• Cp*RuCl-catalyzed [2 + 2 + 2] cycloadditions of alpha,omega-diynes with electron-deficient carbon-heteroatom multiple bonds leading to heterocycles.

  Journal of the American Chemical Society 20050119

• Catalytic, asymmetric synthesis of cyanohydrin ethyl carbonates.

  Organic letters 20031113

• 2-azabicyclo[2.2.2]octa-3,5-dione via a nitrile Diels-Alder reaction.

  The Journal of organic chemistry 20031017