625-05-8 | 3-Amino-3-methylbutyric acid

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$9.00	$6.00
5g	98%	in stock	$17.00	$12.00
10g	97%	in stock	$28.00	$19.00
100g	98%	in stock	$257.00	$180.00

Description

• Catalog Number: AB49092
• Chemical Name: 3-Amino-3-methylbutyric acid
• CAS Number: 625-05-8
• Molecular Formula: C5H11NO2
• Molecular Weight: 117.1463
• MDL Number: MFCD06245495
• SMILES: OC(=O)CC(N)(C)C

Computed Properties

• Complexity: 98.6
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 8
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 2
• XLogP3: -2.9

Literature

• Amino acid transport system A is involved in inflammatory nociception in rats.

  Brain research 20120417

• Tertiary active transport of amino acids reconstituted by coexpression of System A and L transporters in Xenopus oocytes.

  American journal of physiology. Endocrinology and metabolism 20090901

• Temperature dependence of rotational disorder in a non-standard amino acid from X-ray crystallography and molecular dynamics simulation.

  Physical chemistry chemical physics : PCCP 20090421

• NMR-spectroscopy-based metabonomic approach to the analysis of Bay41-4109, a novel anti-HBV compound, induced hepatotoxicity in rats.

  Toxicology letters 20070928

• Acidosis-sensing glutamine pump SNAT2 determines amino acid levels and mammalian target of rapamycin signalling to protein synthesis in L6 muscle cells.

  Journal of the American Society of Nephrology : JASN 20070501

• Differentiation of three pairs of positional isomers of hybrid peptides with repeats of phenylalanine-beta3-h-valine/beta3-valine-phenylalanine by electrospray ionization tandem mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20070101

• Human radiation dosimetry of [11C]MeAIB, a new tracer for imaging of system A amino acid transport.

  European journal of nuclear medicine and molecular imaging 20061001

• N-(methylamino)isobutyric acid inhibits proliferation of CFSC-2C hepatic stellate cells.

  Biochemical pharmacology 20040715

• Inhibition of glutamine transport depletes glutamate and GABA neurotransmitter pools: further evidence for metabolic compartmentation.

  Journal of neurochemistry 20030401

• Uptake of [N-methyl-11C]alpha-methylaminoisobutyric acid in untreated head and neck cancer studied by PET.

  European journal of nuclear medicine and molecular imaging 20030101

• Amino acid uptake in the skeletal muscle measured using [11C]methylaminoisobutyrate (MEAIB) and PET.

  European journal of nuclear medicine and molecular imaging 20021101

• Biodistribution of [11C] methylaminoisobutyric acid, a tracer for PET studies on system A amino acid transport in vivo.

  European journal of nuclear medicine 20010701