625-51-4 | N-(Hydroxymethyl)acetamide

Packsize	Purity	Availability	Price	Discounted Price
1g	96%	in stock	$14.00	$10.00
5g	96%	in stock	$21.00	$15.00
25g	96%	in stock	$26.00	$19.00

Description

• Catalog Number: AB49182
• Chemical Name: N-(Hydroxymethyl)acetamide
• CAS Number: 625-51-4
• Molecular Formula: C3H7NO2
• Molecular Weight: 89.0932
• MDL Number: MFCD00014417
• SMILES: CC(=O)NCO

Computed Properties

• Complexity: 52.8
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 6
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 1
• XLogP3: -1

Upstream Synthesis Route

N-(Hydroxymethyl)acetamide is a versatile compound commonly utilized in chemical synthesis due to its unique properties and reactivity. In organic chemistry, it serves as a valuable building block for the synthesis of various complex molecules. Its functional groups enable it to participate in a wide range of chemical reactions, making it a valuable reagent in the production of pharmaceuticals, agrochemicals, and materials science.One of the key applications of N-(Hydroxymethyl)acetamide is in the formation of amides and esters through condensation reactions. By reacting with appropriate carboxylic acids or acid chlorides, this compound can be used to form a variety of amide and ester derivatives. Additionally, its hydroxyl group can undergo further chemical transformations, allowing for the introduction of other functional groups and increasing the compound's synthetic utility.Moreover, N-(Hydroxymethyl)acetamide can also act as a protecting group for amines in organic synthesis. By temporarily blocking the amino group with this compound, chemists can selectively modify other reactive sites in a molecule without affecting the amine functionality. This strategy is commonly employed in the synthesis of complex natural products and pharmaceutical intermediates.Overall, the versatility and reactivity of N-(Hydroxymethyl)acetamide make it a valuable tool in the toolbox of synthetic chemists, enabling the efficient and controlled construction of intricate molecular structures.

Literature

• New trends in nucleoside biotechnology.

  Acta naturae 20100701

• Immunity and other defenses in pea aphids, Acyrthosiphon pisum.

  Genome biology 20100101