62561-75-5 | (2R)-2-amino-3-(4-iodophenyl)propanoic acid

Packsize	Purity	Availability	Price	Discounted Price
1g	97%	in stock	$26.00	$18.00
5g	97%	in stock	$65.00	$45.00
10g	97%	in stock	$98.00	$69.00
25g	97%	in stock	$211.00	$148.00
100g	97%	in stock	$713.00	$499.00

Description

• Catalog Number: AB78375
• Chemical Name: (2R)-2-amino-3-(4-iodophenyl)propanoic acid
• CAS Number: 62561-75-5
• Molecular Formula: C9H10INO2
• Molecular Weight: 291.0857
• MDL Number: MFCD00063067
• SMILES: N[C@@H](C(=O)O)Cc1ccc(cc1)I

Computed Properties

• Complexity: 179
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 13
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 3
• XLogP3: -0.9

Literature

• Differentiation of enantiomeric drugs by iodo-substituted L-amino acid references under electrospray ionization mass spectrometric conditions.

  Rapid communications in mass spectrometry : RCM 20120615

• A de novo peptide hexamer with a mutable channel.

  Nature chemical biology 20111030

• An alternative and expedient synthesis of radioiodinated 4-iodophenylalanine.

  Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20111001

• Site-specific incorporation of 4-iodo-L-phenylalanine through opal suppression.

  Journal of biochemistry 20100801

• One plasmid selection system for the rapid evolution of aminoacyl-tRNA synthetases.

  Bioorganic & medicinal chemistry letters 20090715

• Improved synthesis of no-carrier-added p-[124I]iodo-L-phenylalanine and p-[131I]iodo-L-phenylalanine for nuclear medicine applications in malignant gliomas.

  Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20080401

• Intra-individual comparison of p-[123I]-iodo-L-phenylalanine and L-3-[123I]-iodo-alpha-methyl-tyrosine for SPECT imaging of gliomas.

  European journal of nuclear medicine and molecular imaging 20080101

• Para-[(123)I]iodo-L-phenylalanine in patients with pancreatic adenocarcinoma: tumour uptake, whole-body kinetics, dosimetry.

  Nuklearmedizin. Nuclear medicine 20080101

• 123/125I-labelled 2-iodo-L: -phenylalanine and 2-iodo-D: -phenylalanine: comparative uptake in various tumour types and biodistribution in mice.

  European journal of nuclear medicine and molecular imaging 20060801

• Use of the Sonogashira coupling reaction for the 'two-step' labeling of phenylalanine peptide side chains with organometallic compounds.

  Bioconjugate chemistry 20060101

• Neighbouring group processes in the deamination of protonated phenylalanine derivatives.

  Organic & biomolecular chemistry 20051021

• Validation of brain tumour imaging with p-[123I]iodo-L-phenylalanine and SPECT.

  European journal of nuclear medicine and molecular imaging 20050901

• The site-specific incorporation of p-iodo-L-phenylalanine into proteins for structure determination.

  Nature biotechnology 20041001

• Binding of inhibitory aromatic amino acids to Streptomyces griseus aminopeptidase.

  Acta crystallographica. Section D, Biological crystallography 20041001

• Phasing in iodine for structure determination.

  Nature biotechnology 20041001

• p-[123I]iodo-L-phenylalanine for detection of pancreatic cancer: basic investigations of the uptake characteristics in primary human pancreatic tumour cells and evaluation in in vivo models of human pancreatic adenocarcinoma.

  European journal of nuclear medicine and molecular imaging 20040401

• Action and efficacy of p-[131I]iodo-L-phenylalanine on primary human glioma cell cultures and rats with C6-gliomas.

  Anticancer research 20040101

• An expanded eukaryotic genetic code.

  Science (New York, N.Y.) 20030815

• Initial evaluation of the feasibility of single photon emission tomography with p-[123 I]iodo-L-phenylalanine for routine brain tumour imaging.

  Nuclear medicine communications 20020201

• Four color fret dye nucleotide terminators for DNA sequencing.

  Nucleosides, nucleotides & nucleic acids 20010101