62596-29-6 | Morusin

Packsize	Purity	Availability	Price	Discounted Price
1mg	98%	in stock	$41.00	$29.00
5mg	98%	in stock	$157.00	$110.00
10mg	98%	in stock	$207.00	$145.00
20mg	98%	in stock	$394.00	$276.00
25mg	98%	in stock	$441.00	$309.00
50mg	98%	in stock	$791.00	$554.00

Description

• Catalog Number: AG69450
• Chemical Name: Morusin
• CAS Number: 62596-29-6
• Molecular Formula: C25H24O6
• Molecular Weight: 420.4545
• MDL Number: MFCD09953814
• SMILES: CC(=CCc1c(oc2c(c1=O)c(O)cc1c2C=CC(O1)(C)C)c1ccc(cc1O)O)C
• NSC Number: 649220

Computed Properties

• Complexity: 805
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 31
• Hydrogen Bond Acceptor Count: 6
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 3
• XLogP3: 5.5

Literature

• Morusin induces paraptosis-like cell death through mitochondrial calcium overload and dysfunction in epithelial ovarian cancer.

  Chemico-biological interactions 20180301

• Involvement of the antioxidative property of morusin in blocking phorbol ester-induced malignant transformation of JB6 P(+) mouse epidermal cells.

  Chemico-biological interactions 20170225

• Antitumor progression potential of morusin suppressing STAT3 and NFκB in human hepatoma SK-Hep1 cells.

  Toxicology letters 20150122

• Protection of prenylated flavonoids from Mori Cortex Radicis (Moraceae) against nitric oxide-induced cell death in neuroblastoma SH-SY5Y cells.

  Archives of pharmacal research 20120101

• Inhibitory effects of constituents from Morus alba var. multicaulis on differentiation of 3T3-L1 cells and nitric oxide production in RAW264.7 cells.

  Molecules (Basel, Switzerland) 20110719

• Inhibition and structural reliability of prenylated flavones from the stem bark of Morus lhou on β-secretase (BACE-1).

  Bioorganic & medicinal chemistry letters 20110515

• Isolation of cholinesterase-inhibiting flavonoids from Morus lhou.

  Journal of agricultural and food chemistry 20110511

• The biochemical and cellular basis for nutraceutical strategies to attenuate neurodegeneration in Parkinson's disease.

  International journal of molecular sciences 20110101

• Induction of Biologically Active Flavonoids in Cell Cultures of Morus nigra and Testing their Hypoglycemic Efficacy.

  Scientia pharmaceutica 20110101

• Cytotoxic prenylated flavonoids from Morus alba.

  Fitoterapia 20101201

• Prenylated flavones from Artocarpus altilis.

  Journal of natural medicines 20101001

• New isoprenylated flavonoids and cytotoxic constituents from Artocarpus tonkinensis.

  Journal of Asian natural products research 20100701

• New isoprenylated flavonoid from Morus alba.

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100601

• Inhibitory effects on mushroom tyrosinase by flavones from the stem barks of Morus lhou (S.) Koidz.

  Journal of enzyme inhibition and medicinal chemistry 20081201

• [Studies on chemical constituents from twigs of Morus atropurpurea].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20081101

• Morusin induces apoptosis and suppresses NF-kappaB activity in human colorectal cancer HT-29 cells.

  Biochemical and biophysical research communications 20080718

• Phenolic constituents from the wood of Morus australis with cytotoxic activity.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20080101

• [Studies on chemical constituents from bark of Morus nigra].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20071201

• [Determination of morusin in cortex mori].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070601

• Hypoglycemic effect of Egyptian Morus alba root bark extract: effect on diabetes and lipid peroxidation of streptozotocin-induced diabetic rats.

  Journal of ethnopharmacology 20050914

• Antimicrobial and cytotoxic activity of 18 prenylated flavonoids isolated from medicinal plants: Morus alba L., Morus mongolica Schneider, Broussnetia papyrifera (L.) Vent, Sophora flavescens Ait and Echinosophora koreensis Nakai.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20041101

• Antinephritis and radical scavenging activity of prenylflavonoids.

  Fitoterapia 20031201

• Root turnover: an important source of microbial substrates in rhizosphere remediation of recalcitrant contaminants.

  Environmental science & technology 20020401

• Effects of naturally occurring prenylated flavonoids on enzymes metabolizing arachidonic acid: cyclooxygenases and lipoxygenases.

  Biochemical pharmacology 20011101

• Cytotoxic activity of low molecular weight polyphenols against human oral tumor cell lines.

  Anticancer research 20000101