6268-49-1 | 4-Dimethylaminoazobenzene-4'-carboxylic acid

Packsize	Purity	Availability	Price	Discounted Price
1g	97%	in stock	$20.00	$14.00
5g	97%	in stock	$57.00	$40.00
25g	97%	in stock	$208.00	$146.00
100g	97%	in stock	$624.00	$437.00

Description

• Catalog Number: AB67365
• Chemical Name: 4-Dimethylaminoazobenzene-4'-carboxylic acid
• CAS Number: 6268-49-1
• Molecular Formula: C15H15N3O2
• Molecular Weight: 269.2985
• MDL Number: MFCD00058988
• SMILES: CN(c1ccc(cc1)/N=N/c1ccc(cc1)C(=O)O)C
• NSC Number: 36265

Computed Properties

• Complexity: 341
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 20
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 4
• XLogP3: 4.1

Literature

• Extra- and intracellular imaging of human matrix metalloprotease 11 (hMMP-11) with a cell-penetrating FRET substrate.

  The Journal of biological chemistry 20121102

• DFT study of the interaction between the conjugated fluorescein and dabcyl system, using fluorescene quenching method.

  Journal of molecular modeling 20120901

• A host-guest-recognition-based electrochemical aptasensor for thrombin detection.

  Biosensors & bioelectronics 20120515

• Probing Y-shaped DNA structure with time-resolved FRET.

  Nanoscale 20120307

• Development of on-line high performance liquid chromatography (HPLC)-biochemical detection methods as tools in the identification of bioactives.

  International journal of molecular sciences 20120101

• A 'turn-on' fluorescent chemosensor based on peptidase for detecting copper(II).

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20120101

• A new electrochemical biosensor for DNA detection based on molecular recognition and lead sulfide nanoparticles.

  Analytical biochemistry 20111215

• A simple 'molecular beacon'-based fluorescent sensing strategy for sensitive and selective detection of mercury (II).

  Chemical communications (Cambridge, England) 20111128

• Direct and continuous fluorescence-based measurements of Pyrococcus horikoshii DNA N-6 adenine methyltransferase activity.

  Analytical biochemistry 20111115

• Comparison of three rapid and easy bacterial DNA extraction methods for use with quantitative real-time PCR.

  European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20110901

• Detection of mercury and phenylmercury ions using DNA-based fluorescent probe.

  The Analyst 20110821

• Mechanism of antisense oligonucleotide interaction with natural RNAs.

  Journal of biomolecular structure & dynamics 20110801

• The application of β-cyclodextrin derivative functionalized aligned carbon nanotubes for electrochemically DNA sensing via host-guest recognition.

  Analytica chimica acta 20110309

• Lensless CCD-based fluorometer using a micromachined optical Söller collimator.

  Lab on a chip 20110307

• Construction of a 'turn-on' fluorescent probe system for His-tagged proteins.

  Bioorganic & medicinal chemistry letters 20101201

• Modulation of notch-1 signaling alleviates vascular endothelial growth factor-mediated diabetic nephropathy.

  Diabetes 20100801

• A FRET-based microplate assay for human protein kinase CK2, a target in neoplastic disease.

  Journal of enzyme inhibition and medicinal chemistry 20100401

• Brain-derived neurotrophic factor and epidermal growth factor activate neuronal m-calpain via mitogen-activated protein kinase-dependent phosphorylation.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20100120

• Recent trends in monitoring of European water framework directive priority substances using micro-sensors: a 2007-2009 review.

  Sensors (Basel, Switzerland) 20100101

• Profiling of calpain activity with a series of FRET-based substrates.

  Biochimica et biophysica acta 20091001

• Highly selective DNA-based sensor for lead(II) and mercury(II) ions.

  Analytical chemistry 20090315

• Molecular beacon-based real-time PCR detection of primary isolates of Salmonella Typhimurium and Salmonella Enteritidis in environmental and clinical samples.

  BMC microbiology 20090101

• Protein Never in Mitosis Gene A Interacting-1 regulates calpain activity and the degradation of cyclooxygenase-2 in endothelial cells.

  Journal of inflammation (London, England) 20090101

• Pyrene excimer signaling molecular beacons for probing nucleic acids.

  Journal of the American Chemical Society 20080109

• Dynamic compression counteracts IL-1beta induced inducible nitric oxide synthase and cyclo-oxygenase-2 expression in chondrocyte/agarose constructs.

  Arthritis research & therapy 20080101

• A continuous assay for foot-and-mouth disease virus 3C protease activity.

  Analytical biochemistry 20070915

• Entrapment of fluorescence signaling DNA enzymes in sol-gel-derived materials for metal ion sensing.

  Analytical chemistry 20070501

• Catalysis and rational engineering of trans-acting pH6DZ1, an RNA-cleaving and fluorescence-signaling deoxyribozyme with a four-way junction structure.

  Chembiochem : a European journal of chemical biology 20060901

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Frequency of common HFE variants in the Saudi population: a high throughput molecular beacon-based study.

  BMC medical genetics 20060101

• Mechanism of translocation and kinetics of DNA unwinding by the helicase RecG.

  Biochemistry 20051227

• Characterization of SARS main protease and inhibitor assay using a fluorogenic substrate.

  Biochemical and biophysical research communications 20040611

• Use of a multiple-enzyme/multiple-reagent assay system to quantify activity levels in samples containing mixtures of matrix metalloproteinases.

  Biochemistry 20040323

• Quantitation of cytomegalovirus (hCMV) DNA and beta-actin DNA by duplex real-time fluorescence PCR in solid organ (liver) transplant recipients.

  Medical microbiology and immunology 20031101

• Stage-specific profiling of Plasmodium falciparum proteases using an internally quenched multispecificity protease substrate.

  Biochemical and biophysical research communications 20031003

• Proteolytic stability of beta-peptide bonds probed using quenched fluorescent substrates incorporating a hemoglobin cleavage site.

  FEBS letters 20030130

• Chimeric RNA-DNA molecular beacon assay for ribonuclease H activity.

  Molecular and cellular probes 20020801

• HLA-DRB fluorotyping by dark quenching and automated analysis.

  Tissue antigens 20011001

• Ultrasensitive optical DNA biosensor based on surface immobilization of molecular beacon by a bridge structure.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20011001

• Simultaneous absolute quantification of target and control templates by real-time fluorescence reverse transcription-PCR using 4-(4'-dimethylaminophenylazo)benzoic acid as a dark quencher dye.

  Clinical chemistry 20010301

• Real Time PCR Using Molecular Beacons : A New Tool to Identify Point Mutations and to Analyze Gene Expression in Mycobacterium tuberculosis.

  Methods in molecular medicine 20010101

• Novel fluorogenic substrates for assaying retroviral proteases by resonance energy transfer.

  Science (New York, N.Y.) 19900223