6329-61-9 | Decahydroisoquinoline

Packsize	Purity	Availability	Price	Discounted Price
1g	95%	in stock	$33.00	$23.00
5g	95%	in stock	$56.00	$39.00
25g	95%	in stock	$177.00	$124.00
100g	95%	in stock	$510.00	$357.00

Description

• Catalog Number: AB72501
• Chemical Name: Decahydroisoquinoline
• CAS Number: 6329-61-9
• Molecular Formula: C9H17N
• Molecular Weight: 139.23798000000002
• MDL Number: MFCD00012096
• SMILES: C1CCC2C(C1)CNCC2
• NSC Number: 43479

Computed Properties

• Complexity: 111
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 10
• Hydrogen Bond Acceptor Count: 1
• Hydrogen Bond Donor Count: 1
• Undefined Atom Stereocenter Count: 2
• XLogP3: 2.2

Literature

• Protic ionic liquids based on decahydroisoquinoline: lost superfragility and ionicity-fragility correlation.

  The journal of physical chemistry. B 20120112

• Physiology and pathology of calcium signaling in the brain.

  Frontiers in pharmacology 20120101

• Essential structure of opioid κ receptor agonist nalfurafine for binding to κ receptor 1: synthesis of decahydroisoquinoline derivatives and their pharmacologies.

  Chemical & pharmaceutical bulletin 20120101

• Sulfinylated azadecalins act as functional mimics of a pollen germination stimulant in Arabidopsis pistils.

  The Plant journal : for cell and molecular biology 20111201

• Remodelling of the natural product fumagillol employing a reaction discovery approach.

  Nature chemistry 20111201

• Drug discovery using chemical systems biology: weak inhibition of multiple kinases may contribute to the anti-cancer effect of nelfinavir.

  PLoS computational biology 20110401

• Amygdalar glutamatergic neuronal systems play a key role on the hibernating state of hamsters.

  BMC neuroscience 20110101

• Molecular Basis for Drug Resistance in HIV-1 Protease.

  Viruses 20101101

• Straightforward assembly of the octahydroisoquinoline core of morphinan alkaloids.

  Organic letters 20100521

• Diastereoselective synthesis of a highly functionalized angularly substituted cis-perhydroisoquinoline-3,6-dione via organoiron.

  The Journal of organic chemistry 20100305

• Decahydroisoquinoline derivatives as novel non-peptidic, potent and subtype-selective somatostatin sst(3) receptor antagonists.

  Bioorganic & medicinal chemistry letters 20100301

• Abundant lattice inclusion phenomenon with sterically hindered and inherently shape-selective tetraarylpyrenes.

  The Journal of organic chemistry 20091120

• Drug-resistant molecular mechanism of CRF01_AE HIV-1 protease due to V82F mutation.

  Journal of computer-aided molecular design 20090501

• 1H-Pyrazolo[3,4-g]hexahydro-isoquinolines as selective glucocorticoid receptor antagonists with high functional activity.

  Bioorganic & medicinal chemistry letters 20080215

• 2-Benzenesulfonyl-8a-benzyl-hexahydro-2H-isoquinolin-6-ones as selective glucocorticoid receptor antagonists.

  Bioorganic & medicinal chemistry letters 20071015

• Subtype selectivity and flexibility of ionotropic glutamate receptors upon antagonist ligand binding.

  Organic & biomolecular chemistry 20060321

• Dielectric and shear mechanical alpha and beta relaxations in seven glass-forming liquids.

  The Journal of chemical physics 20051215

• Two secondary modes in decahydroisoquinoline: which one is the true Johari Goldstein process?

  The Journal of chemical physics 20050615

• Locomotor activity detects subunit-selective effects of agonists and decahydroisoquinoline antagonists at AMPA/kainic acid ionotropic glutamate receptors in adult rats.

  Psychopharmacology 20050401

• Differential modulation of microglia superoxide anion and thromboxane B2 generation by the marine manzamines.

  BMC pharmacology 20050101

• Pharmacological characterization of glutamatergic agonists and antagonists at recombinant human homomeric and heteromeric kainate receptors in vitro.

  Neuropharmacology 20040501

• Rhodium-catalyzed anti-Markovnikov hydroamination of vinylarenes.

  Journal of the American Chemical Society 20030514

• [Synthetic study of biologically important nitrogen containing natural products: development of new methodology and design of leading compounds for new pharmaceuticals].

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20030401

• CYP3A4-mediated hepatic metabolism of the HIV-1 protease inhibitor saquinavir in vitro.

  Xenobiotica; the fate of foreign compounds in biological systems 20020101

• Ring closing metathesis mediated synthesis of 4a-aryloxodecahydroisoquinolines, intermediates in the preparation of novel opiates.

  Organic letters 20011101

• Inhibitors of AMPA and kainate receptors.

  Current medicinal chemistry 20010901

• Role of AMPA and GluR5 kainate receptors in the development and expression of amygdala kindling in the mouse.

  Neuropharmacology 20010101