6338-41-6 | 5-Hydroxymethyl-2-furancarboxylic acid

Packsize	Purity	Availability	Price	Discounted Price
250mg	98%	in stock	$6.00	$4.00
1g	98%	in stock	$8.00	$5.00
5g	98%	in stock	$16.00	$11.00
10g	98%	in stock	$28.00	$19.00
25g	98%	in stock	$63.00	$44.00
100g	98%	in stock	$212.00	$148.00

Description

• Catalog Number: AB45323
• Chemical Name: 5-Hydroxymethyl-2-furancarboxylic acid
• CAS Number: 6338-41-6
• Molecular Formula: C6H6O4
• Molecular Weight: 142.1094
• MDL Number: MFCD03274472
• SMILES: OCc1ccc(o1)C(=O)O
• NSC Number: 40739

Computed Properties

• Complexity: 134
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 10
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 2

Upstream Synthesis Route

5-Hydroxymethyl-2-furancarboxylic acid, also known as HMF, is a versatile compound commonly used in chemical synthesis. Its unique structure and properties make it a valuable building block in various organic reactions.One key application of 5-Hydroxymethyl-2-furancarboxylic acid is in the synthesis of pharmaceuticals. This compound can serve as a precursor to various drug molecules due to its ability to undergo different chemical transformations. By incorporating HMF into the synthesis pathway, chemists can access a wide range of pharmaceutical compounds with desirable properties.Additionally, 5-Hydroxymethyl-2-furancarboxylic acid is also utilized in the production of agrochemicals. Its reactivity and functional groups make it suitable for creating pesticides and herbicides that are effective in agriculture. Chemists can modify HMF to introduce specific properties that enhance the performance of these agrochemical products.Furthermore, this compound plays a crucial role in the development of materials science. By utilizing the unique reactivity of 5-Hydroxymethyl-2-furancarboxylic acid, researchers can design and synthesize new materials with tailored properties. These materials may find applications in various industries, including electronics, coatings, and adhesives.In conclusion, 5-Hydroxymethyl-2-furancarboxylic acid is a versatile compound with diverse applications in chemical synthesis. Its role in pharmaceutical, agrochemical, and materials science highlights its importance as a valuable building block in organic chemistry.

Literature

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  Mutagenesis 20120101

• Trace amounts of furan-2-carboxylic acids determine the quality of solid agar plates for bacterial culture.

  PloS one 20120101

• Microbial degradation of furanic compounds: biochemistry, genetics, and impact.

  Applied microbiology and biotechnology 20111201

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• Estimation of dietary intake of 5-hydroxymethylfurfural and related substances from coffee to Spanish population.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100201

• Gold-catalyzed aerobic oxidation of 5-hydroxymethylfurfural in water at ambient temperature.

  ChemSusChem 20090720

• Microcirculatory effects of changing blood hemoglobin oxygen affinity during hemorrhagic shock resuscitation in an experimental model.

  Shock (Augusta, Ga.) 20090601

• Biomass into chemicals: aerobic oxidation of 5-hydroxymethyl-2-furfural into 2,5-furandicarboxylic acid with gold nanoparticle catalysts.

  ChemSusChem 20090101

• Dietary exposure to 5-hydroxymethylfurfural from Norwegian food and correlations with urine metabolites of short-term exposure.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20081201

• Suppression of blood lipid concentrations by volatile Maillard reaction products.

  Nutrition (Burbank, Los Angeles County, Calif.) 20080101

• Formation of 5-hydroxymethyl-2-furfural (HMF) and 5-hydroxymethyl-2-furoic acid during roasting of coffee.

  Molecular nutrition & food research 20070401

• Nematicidal activity of 5-hydroxymethyl-2-furoic acid against plant-parasitic nematodes.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20070101

• Identification and urinary excretion of metabolites of 5-(hydroxymethyl)-2-furfural in human subjects following consumption of dried plums or dried plum juice.

  Journal of agricultural and food chemistry 20060517

• Oxidation of heterocyclic and aromatic aldehydes to the corresponding carboxylic acids by Acetobacter and Serratia strains.

  Biotechnology letters 20041101

• New secondary metabolites from the marine endophytic fungus Apiospora montagnei.

  Journal of natural products 20040601

• A new antioxidant isobenzofuranone derivative from the algicolous marine fungus Epicoccum sp.

  Planta medica 20030901

• Two new xanthone derivatives from the algicolous marine fungus Wardomyces anomalus.

  Journal of natural products 20030501

• New macrolides and furan carboxylic acid derivative from the sponge-derived fungus Cladosporium herbarum.

  Journal of natural products 20010401