636-26-0 | 5-Methyl-2-thiouracil

Packsize	Purity	Availability	Price	Discounted Price
1g	95%	in stock	$25.00	$18.00
5g	95%	in stock	$26.00	$18.00
25g	95%	in stock	$60.00	$42.00
100g	95%	in stock	$203.00	$142.00

Description

• Catalog Number: AB67647
• Chemical Name: 5-Methyl-2-thiouracil
• CAS Number: 636-26-0
• Molecular Formula: C5H6N2OS
• Molecular Weight: 142.1789
• MDL Number: MFCD00009777
• SMILES: Cc1c[nH]c(=S)[nH]c1=O
• NSC Number: 9377

Computed Properties

• Complexity: 197
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 9
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 2

Literature

• Binding of metal ions by pyrimidine base pairs in DNA duplexes.

  Chemical Society reviews 20111201

• Role of the heat capacity change in understanding and modeling melting thermodynamics of complementary duplexes containing standard and nucleobase-modified LNA.

  Biochemistry 20110614

• Excited-state dynamics of 6-aza-2-thiothymine and 2-thiothymine: highly efficient intersystem crossing and singlet oxygen photosensitization.

  The journal of physical chemistry. B 20100708

• 2'-Modified oligonucleotides for antisense therapeutics.

  Current topics in medicinal chemistry 20070101

• Influence of thioketo substitution on the properties of uracil and its noncovalent interactions with alkali metal ions: threshold collision-induced dissociation and theoretical studies.

  The journal of physical chemistry. A 20060202

• EPR study of a copper impurity center in a single crystal of 2-thiothymine.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20051001

• Role of histidine-85 in the catalytic mechanism of thymidine phosphorylase as assessed by targeted molecular dynamics simulations and quantum mechanical calculations.

  Biochemistry 20040120

• 5-Methyl-2-thiouracil.

  Acta crystallographica. Section C, Crystal structure communications 20020901

• Structure-activity relationship of ligands of uracil phosphoribosyltransferase from Toxoplasma gondii.

  Biochemical pharmacology 19940817