636-99-7 | (4-Nitrophenyl)hydrazine, HCl

Packsize	Purity	Availability	Price	Discounted Price
25g	98%	in stock	$13.00	$10.00
100g	98%	in stock	$40.00	$28.00
500g	98%	in stock	$150.00	$105.00

Description

• Catalog Number: AB68148
• Chemical Name: (4-Nitrophenyl)hydrazine, HCl
• CAS Number: 636-99-7
• Molecular Formula: C6H8ClN3O2
• Molecular Weight: 189.59962
• MDL Number: MFCD00040592
• SMILES: NNc1ccc(cc1)N(=O)=O.Cl

Computed Properties

• Complexity: 137
• Covalently-Bonded Unit Count: 2
• Heavy Atom Count: 12
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 1

Upstream Synthesis Route

The hydrazine derivative, (4-nitrophenyl)- hydrochloride (1:1), is a versatile compound widely employed in chemical synthesis processes. With its unique chemical properties, this compound serves as a key reagent in various reactions, particularly in organic synthesis. One of the primary applications of (4-nitrophenyl)- hydrazine hydrochloride lies in its role as a powerful reducing agent. Its ability to donate electrons makes it valuable in reducing important functional groups, such as carbonyl compounds, to yield desired products. This compound also participates in the synthesis of heterocyclic compounds by engaging in cyclization reactions, thus expanding its utility in drug discovery and material science applications. Furthermore, (4-nitrophenyl)- hydrazine hydrochloride can be utilized in the preparation of diverse organic compounds with specific functionalities, owing to its reactivity towards various substrates. Its involvement in the formation of C-N bonds, through nucleophilic addition reactions, makes it a valuable building block in the construction of complex molecules. Overall, (4-nitrophenyl)- hydrazine hydrochloride offers chemists a valuable tool for manipulating chemical structures and facilitating the synthesis of novel compounds in the realm of organic chemistry.

Literature

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  PloS one 20120101

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  Journal of the American Chemical Society 20030521

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  Biochimica et biophysica acta 20030411

• Two amine oxidases from Aspergillus niger AKU 3302 contain topa quinone as the cofactor: unusual cofactor link to the glutamyl residue occurs only at one of the enzymes.

  Biochimica et biophysica acta 19960607

• Active-site covalent modifications of quinoprotein amine oxidases from Aspergillus niger. Evidence for binding of the mechanism-based inhibitor, 1,4-diamino-2-butyne, to residue Lys356 involved in the catalytic cycle.

  European journal of biochemistry 19941101