637-01-4 | N,N,N',N'-Tetramethyl-p-phenylenediamine DiHCl

Packsize	Purity	Availability	Price	Discounted Price
250mg	95%	in stock	$16.00	$11.00
1g	95%	in stock	$19.00	$13.00
5g	95%	in stock	$36.00	$25.00
25g	95%	in stock	$128.00	$90.00
100g	95%	in stock	$349.00	$245.00

Description

• Catalog Number: AG65321
• Chemical Name: N,N,N',N'-Tetramethyl-p-phenylenediamine DiHCl
• CAS Number: 637-01-4
• Molecular Formula: C10H18Cl2N2
• Molecular Weight: 237.1693
• MDL Number: MFCD00012482
• SMILES: CN(c1ccc(cc1)N(C)C)C.Cl.Cl

Computed Properties

• Complexity: 108
• Covalently-Bonded Unit Count: 3
• Heavy Atom Count: 14
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 2

Literature

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  The Journal of toxicological sciences 20140201

• The redox state of cytochrome c modulates resistance to methotrexate in human MCF7 breast cancer cells.

  PloS one 20130101

• Tetramethylphenylenediamine protects the isolated heart against ischaemia-induced apoptosis and reperfusion-induced necrosis.

  British journal of pharmacology 20110301

• Photoreactions and molecular dynamics of radical pairs in a reversed micelle studied by time-resolved measurements of EPR and magnetic field effect.

  The journal of physical chemistry. B 20101118

• Comparative antioxidant activities and synergism of resveratrol and oxyresveratrol.

  Natural product research 20101101

• Interaction of C(60) fullerene with lipids.

  Chemistry and physics of lipids 20100601

• Using N,N,N',N'-tetramethyl-p-phenylenediamine (TMPD) to assay cyclooxygenase activity in vitro.

  Methods in molecular biology (Clifton, N.J.) 20100101

• Contralateral leg as a control during skeletal muscle ischemia-reperfusion.

  The Journal of surgical research 20090701

• Evidence for the presence of prostaglandin H synthase like enzyme in female Setaria cervi and its inhibition by diethylcarbamazine.

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  FEBS letters 20081029

• Photoreactions of 1,4-naphthoquinone with lysozyme studied by laser flash photolysis and steady-state analysis.

  Journal of photochemistry and photobiology. B, Biology 20080821

• Tetramethylphenylenediamine-induced hepatocyte cytotoxicity caused by lysosomal labilisation and redox cycling with oxygen activation.

  Chemico-biological interactions 20080310

• Mitochondrial regulation of caspase activation by cytochrome oxidase and tetramethylphenylenediamine via cytosolic cytochrome c redox state.

  The Journal of biological chemistry 20071026

• The oxidation/reduction kinetics of the plastoquinone pool controls the appearance of the I-peak in the O-J-I-P chlorophyll fluorescence rise: effects of various electron acceptors.

  Journal of photochemistry and photobiology. B, Biology 20070727

• Cyanide-induced death of cells in plant leaves.

  Biochemistry. Biokhimiia 20070501

• Inhibition of reversed electron transfer and proton transport in the beef heart cytochrome bc1 complex by chemical modification.

  Journal of biochemistry 20070301

• Effect of dehydroepiandrosterone (DHEA) treatment on oxidative energy metabolism in rat liver and brain mitochondria. A dose-response study.

  Clinical biochemistry 20070101

• Interaction of N,N,N',N'-tetramethyl-p-phenylenediamine with photosystem II as revealed by thermoluminescence: reduction of the higher oxidation states of the Mn cluster and displacement of plastoquinone from the Q(B) niche.

  Biochimica et biophysica acta 20061101

• Control by cytochrome c oxidase of the cellular oxidative phosphorylation system depends on the mitochondrial energy state.

  The Biochemical journal 20060615

• Stimulation by cytochrome c of the external pathway of NADH oxidation and ascorbate oxidation in the presence of TMPD.

  Doklady. Biochemistry and biophysics 20060101

• Kinetic analyses of the OJIP chlorophyll fluorescence rise in thylakoid membranes.

  Photosynthesis research 20050601

• Cytochrome c association with the inner mitochondrial membrane is impaired in the CNS of G93A-SOD1 mice.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20050105

• Mitochondrial oxidative phosphorylation is defective in the long-lived mutant clk-1.

  The Journal of biological chemistry 20041224

• Arginine 391 in subunit I of the cytochrome bd quinol oxidase from Escherichia coli stabilizes the reduced form of the hemes and is essential for quinol oxidase activity.

  The Journal of biological chemistry 20041224

• Studies on TMPD:TCNB; a donor-acceptor with room temperature paramagnetism and n-pi interaction.

  Molecules (Basel, Switzerland) 20040831

• Partial reconstruction of in vitro gluconeogenesis arising from mitochondrial l-lactate uptake/metabolism and oxaloacetate export via novel L-lactate translocators.

  The Biochemical journal 20040515

• Separation and quantitation of peroxidized phospholipids using high-performance thin-layer chromatography with tetramethyl-p-phenylenediamine detection.

  Analytical biochemistry 20040401

• A cytochrome c-enhanced peroxidation reaction with potential use in screening dietary antioxidants.

  Journal of pharmaceutical and biomedical analysis 20040310

• Heat shock protein 72 binds and protects dihydrofolate reductase against oxidative injury.

  Biochemical and biophysical research communications 20040102

• [The cytochrome cbo from the obligate methylotroph Methylobacillus flagellatus KT is a cytochrome-c oxidase].

  Mikrobiologiia 20040101

• First estimation of C4-H bond dissociation energies of NADH and its radical cation in aqueous solution.

  Journal of the American Chemical Society 20031217

• N,N,N',N'-tetramethyl-p-phenylenediamine initiates the appearance of a well-resolved I peak in the kinetics of chlorophyll fluorescence rise in isolated thylakoids.

  Biochimica et biophysica acta 20031208

• An alternate photosynthetic electron donor system for PSI supports light dependent nitrogen fixation in a non-heterocystous cyanobacterium, Plectonema boryanum.

  Journal of plant physiology 20030101

• Participation of chloroplasts in plant apoptosis.

  Bioscience reports 20030101

• Involvement of K+-ATP-dependent channel in transport of monovalent thallium (Tl+) across the inner membrane of rat liver mitochondria.

  Doklady. Biochemistry and biophysics 20030101

• Singlet oxygen trapping by DRD156 in micellar solutions.

  Life sciences 20021206

• Aeropyrum pernix K1, a strictly aerobic and hyperthermophilic archaeon, has two terminal oxidases, cytochrome ba3 and cytochrome aa3.

  Archives of microbiology 20021201

• The aerobic electron transport system of Eikenella corrodens.

  Canadian journal of microbiology 20021001

• Application of surface-enhanced laser desorption/ionization technology to the detection and identification of urinary parvalbumin-alpha: a biomarker of compound-induced skeletal muscle toxicity in the rat.

  Electrophoresis 20020901

• Carotid body chemosensory excitation induced by nitric oxide: involvement of oxidative metabolism.

  Respiratory physiology & neurobiology 20020801

• Dimerization of organic free radicals in solution. 1. Temperature dependent measurements.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20020401

• Mitochondrial respiration at low levels of oxygen and cytochrome c.

  Biochemical Society transactions 20020401

• Effect of cyclosporin A and its vehicle on cardiac and skeletal muscle mitochondria: relationship to efficacy of the respiratory chain.

  British journal of pharmacology 20010701