64744-50-9 | 4,4-Pentamethylene-2-pyrrolidinone

Packsize	Purity	Availability	Price	Discounted Price
5g	95%	in stock	$18.00	$12.00
10g	95%	in stock	$25.00	$17.00
25g	95%	in stock	$31.00	$22.00
100g	95%	in stock	$92.00	$64.00
500g	95%	in stock	$415.00	$290.00

Description

• Catalog Number: AB66294
• Chemical Name: 4,4-Pentamethylene-2-pyrrolidinone
• CAS Number: 64744-50-9
• Molecular Formula: C9H15NO
• Molecular Weight: 153.2215
• MDL Number: MFCD00177938
• SMILES: O=C1NCC2(C1)CCCCC2

Computed Properties

• Complexity: 170
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 1
• Hydrogen Bond Donor Count: 1
• XLogP3: 1.5

Literature

• The stabilizing effect of moisture on the solid-state degradation of gabapentin.

  AAPS PharmSciTech 20110901

• Novel neuroprotective strategies in ischemic retinal lesions.

  International journal of molecular sciences 20100101

• Gabapentin-lactum-chloranilic acid (1/1).

  Acta crystallographica. Section E, Structure reports online 20100101

• Development and application of a validated HPLC method for the analysis of dissolution samples of gabapentin drug products.

  Journal of pharmaceutical and biomedical analysis 20080107

• Development and application of a validated HPLC method for the determination of gabapentin and its major degradation impurity in drug products.

  Journal of pharmaceutical and biomedical analysis 20070411

• Comparative effects of some hydrophilic excipients on the rate of gabapentin and baclofen lactamization in lyophilized formulations.

  International journal of pharmaceutics 20070306

• Gabapentin-lactam induces dendritic filopodia and motility in cultured hippocampal neurons.

  The Journal of pharmacology and experimental therapeutics 20061001

• Gabapentin-lactam, but not gabapentin, reduces protein aggregates and improves motor performance in a transgenic mouse model of Huntington's disease.

  Naunyn-Schmiedeberg's archives of pharmacology 20040801

• Retinal ganglion cell survival is enhanced by gabapentin-lactam in vitro: evidence for involvement of mitochondrial KATP channels.

  Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20040301

• Determination of gabapentin-lactam in serum of patients under gabapentin therapy.

  Arzneimittel-Forschung 20040101

• The neuroprotective properties of gabapentin-lactam.

  Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20011101

• [The effect of gabapentin and gabapentin-lactam on retinal ganglion cell survival. Situation after acute retinal ischemia in animal models].

  Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 20010301