660867-80-1 | 2-Methylpyridine-4-boronic acid pinacol ester

Packsize	Purity	Availability	Price	Discounted Price
1g	95%	in stock	$16.00	$12.00
5g	95%	in stock	$45.00	$32.00
10g	95%	in stock	$78.00	$55.00
25g	95%	in stock	$194.00	$136.00

Description

• Catalog Number: AB48703
• Chemical Name: 2-Methylpyridine-4-boronic acid pinacol ester
• CAS Number: 660867-80-1
• Molecular Formula: C12H18BNO2
• Molecular Weight: 219.0878
• MDL Number: MFCD08061590
• SMILES: Cc1nccc(c1)B1OC(C(O1)(C)C)(C)C

Computed Properties

• Complexity: 252
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 16
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1

Upstream Synthesis Route

2-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine, commonly known as $name$, is a versatile compound widely utilized in chemical synthesis as a key building block. This compound plays a crucial role in various organic reactions due to its unique structural properties and reactivity.One of the primary applications of 2-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine is as a boron-containing reagent in Suzuki coupling reactions. In these reactions, $name$ serves as a boronic acid source, enabling the formation of carbon-carbon bonds through cross-coupling with aryl or vinyl halides under the catalysis of palladium. This method is widely used in the synthesis of complex organic molecules, such as pharmaceuticals, agrochemicals, and materials.Moreover, 2-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine is also employed in various other transformations, including C-H activation, Buchwald-Hartwig amination, and Heck reactions. Its ability to undergo selective functionalization and regioselective transformations makes it a valuable tool for organic chemists seeking to construct diverse chemical structures efficiently.Overall, the versatile nature of 2-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine makes it a valuable reagent in modern organic synthesis, enabling the rapid and controlled construction of complex molecules with high efficiency and selectivity.