66495-88-3 | 3-Hydroxy-2-methoxybenzaldehyde

Packsize	Purity	Availability	Price	Discounted Price
100mg	98%	in stock	$11.00	$8.00
250mg	95%	in stock	$13.00	$10.00
1g	95%	in stock	$47.00	$33.00
5g	98%	in stock	$187.00	$131.00

Description

• Catalog Number: AH17133
• Chemical Name: 3-Hydroxy-2-methoxybenzaldehyde
• CAS Number: 66495-88-3
• Molecular Formula: C8H8O3
• Molecular Weight: 152.1473
• MDL Number: MFCD06656119
• SMILES: COc1c(C=O)cccc1O

Computed Properties

• Complexity: 135
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 2
• XLogP3: 1

Upstream Synthesis Route

3-Hydroxy-2-methoxybenzaldehyde, also known as vanillin alcohol, is a versatile compound widely used in chemical synthesis. Its unique structure makes it a valuable building block in the production of various pharmaceuticals, fragrances, and flavorings.1. Amidation Reactions: 3-Hydroxy-2-methoxybenzaldehyde can undergo amidation reactions to produce amides, which are important intermediates in the synthesis of pharmaceutical compounds.2. Oxidation Reactions: Due to its phenolic group, this compound can be easily oxidized to form corresponding carboxylic acids or other functional groups, expanding its utility in organic synthesis.3. Mannich Reactions: The aldehyde group in 3-Hydroxy-2-methoxybenzaldehyde is reactive and can participate in Mannich reactions to yield β-amino alcohols, which are key structural motifs in drug discovery and development.In summary, 3-Hydroxy-2-methoxybenzaldehyde is a valuable compound in chemical synthesis due to its ability to participate in various reactions and serve as a precursor for the production of diverse organic compounds.

Literature

• Carbonic anhydrase inhibitors. Inhibition of human erythrocyte isozymes I and II with a series of antioxidant phenols.

  Bioorganic & medicinal chemistry 20090415