66607-27-0 | 3-Iodo-1H-indazole

Packsize	Purity	Availability	Price	Discounted Price
1g	95%	in stock	$8.00	$5.00
5g	95%	in stock	$16.00	$12.00
10g	95%	in stock	$31.00	$22.00
25g	95%	in stock	$77.00	$54.00
100g	95%	in stock	$307.00	$215.00

Description

• Catalog Number: AI03448
• Chemical Name: 3-Iodo-1H-indazole
• CAS Number: 66607-27-0
• Molecular Formula: C7H5IN2
• Molecular Weight: 244.0325
• MDL Number: MFCD04972469
• SMILES: Ic1n[nH]c2c1cccc2

Computed Properties

• Complexity: 129
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 10
• Hydrogen Bond Acceptor Count: 1
• Hydrogen Bond Donor Count: 1
• XLogP3: 2.2

Upstream Synthesis Route

3-Iodo-1H-indazole is a versatile compound that finds widespread application in chemical synthesis. As a reactive and functionalized indazole derivative, it plays a crucial role in various synthetic methodologies for the preparation of complex organic molecules.One key application of 3-Iodo-1H-indazole is as a building block in the synthesis of pharmaceutical compounds. Its unique structural properties make it an ideal precursor for the construction of biologically active molecules, especially in the development of drug candidates. By incorporating 3-Iodo-1H-indazole into synthetic pathways, chemists can access a diverse range of novel compounds with potential medicinal benefits.Furthermore, 3-Iodo-1H-indazole is commonly utilized in transition metal-catalyzed cross-coupling reactions. Its iodine substituent provides a convenient handle for introducing various functional groups onto the indazole scaffold under mild reaction conditions. This enables the rapid assembly of complex molecular structures with high efficiency and selectivity, making it a valuable tool in the toolbox of synthetic chemists.Overall, the versatile nature of 3-Iodo-1H-indazole makes it a valuable reagent in the field of chemical synthesis, offering opportunities for the design and preparation of innovative chemical entities with diverse applications.

Literature

• Design, synthesis and biological evaluation of Trypanosoma brucei trypanothione synthetase inhibitors.

  ChemMedChem 20120102