67915-31-5 | Terconazole

Packsize	Purity	Availability	Price	Discounted Price
25mg	95%	in stock	$33.00	$23.00
50mg	95%	in stock	$62.00	$43.00
100mg	95%	in stock	$74.00	$52.00
250mg	95%	in stock	$114.00	$80.00
1g	95%	in stock	$303.00	$212.00

Description

• Catalog Number: AI54857
• Chemical Name: Terconazole
• CAS Number: 67915-31-5
• Molecular Formula: C26H31Cl2N5O3
• Molecular Weight: 532.462
• MDL Number: MFCD05662369
• SMILES: Clc1ccc(c(c1)Cl)[C@]1(OC[C@@H](O1)COc1ccc(cc1)N1CCN(CC1)C(C)C)Cn1cncn1
• NSC Number: 760361

Computed Properties

• Complexity: 693
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 2
• Heavy Atom Count: 36
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 8
• XLogP3: 4.8

Literature

• Why are most phospholipidosis inducers also hERG blockers?

  Archives of toxicology 20171201

• Elucidating mechanisms of toxicity using phenotypic data from primary human cell systems--a chemical biology approach for thrombosis-related side effects.

  International journal of molecular sciences 20150101

• Propiconazole is a specific and accessible brassinosteroid (BR) biosynthesis inhibitor for Arabidopsis and maize.

  PloS one 20120101

• Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

  PLoS computational biology 20111201

• Boric acid for recurrent vulvovaginal candidiasis: the clinical evidence.

  Journal of women's health (2002) 20110801

• Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2.

  Journal of medicinal chemistry 20110714

• Identification of clinically used drugs that activate pregnane X receptors.

  Drug metabolism and disposition: the biological fate of chemicals 20110101

• Development of a simple liquid chromatography-tandem mass spectrometry method for multiresidue determination of antifungal drugs in chicken tissues.

  Journal of AOAC International 20110101

• Chromatographic and electrophoretic techniques used in the analysis of triazole antifungal agents-a review.

  Talanta 20100915

• 5-(4-Chloro-phen-yl)-3-(2,4-dimethyl-thiazol-5-yl)-1,2,4-triazolo[3,4-a]isoquinoline.

  Acta crystallographica. Section E, Structure reports online 20100501

• Chemical combinations elucidate pathway interactions and regulation relevant to Hepatitis C replication.

  Molecular systems biology 20100101

• About the role of enantioselective selector-selectand interactions and the mobilities of diastereomeric associates in enantiomer separations using CE.

  Electrophoresis 20090801

• Identification of antifungal compounds active against Candida albicans using an improved high-throughput Caenorhabditis elegans assay.

  PloS one 20090101

• Chromatographic/mass spectrometric method for the estimation of itraconazole and its metabolite in human plasma. Application to a bioequivalence study.

  Arzneimittel-Forschung 20090101

• Enantioselective separation of azole compounds by EKC. Reversal of migration order of enantiomers with CD concentration.

  Electrophoresis 20070801

• Three-dimensional quantitative structure-activity relationship analysis of human CYP51 inhibitors.

  Drug metabolism and disposition: the biological fate of chemicals 20070301

• Fungistatic activity of freshly killed termite, Nasutitermes acajutlae, soldiers in the Caribbean.

  Journal of insect science (Online) 20070101

• Inhibition of the enzymatic activity of heme oxygenases by azole-based antifungal drugs.

  The Journal of pharmacology and experimental therapeutics 20061001

• Anti-inflammatory and anti-itch activity of sertaconazole nitrate.

  Archives of dermatological research 20060901

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Enantiomeric separation of ketoconazole and terconazole antifungals by electrokinetic chromatography: Rapid quantitative analysis of ketoconazole in pharmaceutical formulations.

  Electrophoresis 20051001

• Prediction of genotoxicity of chemical compounds by statistical learning methods.

  Chemical research in toxicology 20050601

• Paecilomyces lilacinus vaginitis in an immuno-competent patient.

  Emerging infectious diseases 20030901

• Topical treatment for vaginal candidiasis (thrush) in pregnancy.

  The Cochrane database of systematic reviews 20010101