69098-15-3 | Nickel(ii) chloride hydrate

Packsize	Purity	Availability	Price	Discounted Price
5g	95%	in stock	$25.00	$17.00
25g	95%	in stock	$49.00	$34.00
100g	95%	in stock	$105.00	$74.00
500g	95%	in stock	$305.00	$214.00

Description

• Catalog Number: AB77472
• Chemical Name: Nickel(ii) chloride hydrate
• CAS Number: 69098-15-3
• Molecular Formula: Cl2NiO
• Molecular Weight: 147.61468000000002
• MDL Number: MFCD00149809
• SMILES: [Cl-].[Cl-].[Ni+2].O

Computed Properties

• Complexity: 2.8
• Covalently-Bonded Unit Count: 2
• Heavy Atom Count: 4
• Hydrogen Bond Acceptor Count: 1
• Hydrogen Bond Donor Count: 1

Literature

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  Journal of inorganic biochemistry 20130901

• Anti-apoptotic proteins and catalase-dependent apoptosis resistance in nickel chloride-transformed human lung epithelial cells.

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• Expression, purification, and activity assay of peptide deformylase from Escherichia coli and Staphylococcus aureus.

  Molecular and cellular biochemistry 20111101

• Activation of Akt/GSK3β and Akt/Bcl-2 signaling pathways in nickel-transformed BEAS-2B cells.

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• Two separate Ni(2+) -sensitive voltage-gated Ca(2+) channels modulate transretinal signalling in the isolated murine retina.

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• Chiroptical detection of condensed nickel(II)-Z-DNA in the presence of the B-DNA via porphyrin exciton coupled circular dichroism.

  The journal of physical chemistry. B 20110825

• βig-h3 regulates store-operated Ca2+ entry and promotes the invasion of human hepatocellular carcinoma cells.

  Cell biology international 20110801

• Nickel promotes the invasive potential of human lung cancer cells via TLR4/MyD88 signaling.

  Toxicology 20110711

• Synaptically driven state transitions in distal dendrites of striatal spiny neurons.

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• L-carnitine protects against nickel-induced neurotoxicity by maintaining mitochondrial function in Neuro-2a cells.

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• Calcium microdomains near R-type calcium channels control the induction of presynaptic long-term potentiation at parallel fiber to purkinje cell synapses.

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• Imbalanced K+ and Ca2+ subthreshold interactions contribute to increased hypothalamic presympathetic neuronal excitability in hypertensive rats.

  The Journal of physiology 20110201

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• R-type Ca(2+) channels contribute to fast synaptic excitation and action potentials in subsets of myenteric neurons in the guinea pig intestine.

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• Dendritic calcium signaling in ON and OFF mouse retinal ganglion cells.

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  Chemphyschem : a European journal of chemical physics and physical chemistry 20100201

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  Talanta 20091215

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• Longer lasting electroretinographic recordings from the isolated and superfused murine retina.

  Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20091001

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• Effects of nickel, chromate, and arsenite on histone 3 lysine methylation.

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  Journal of cellular physiology 20090101

• Exploration of mononucleotides as fixed ligands towards chiral discrimination of hexose monosaccharides by the kinetic method.

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  Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20081001

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• Mechanical stress induces tumor necrosis factor-{alpha} production through Ca2+ release-dependent TLR2 signaling.

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  Protein and peptide letters 20080101

• Voltage-gated Ca2+ currents are necessary for slow-wave propagation in the canine gastric antrum.

  American journal of physiology. Cell physiology 20071101

• Effects of nickel on human and fish red blood cells.

  Bioscience reports 20071001

• The Cav3.2/alpha1H T-type Ca2+ current is a molecular determinant of excitatory effects of GABA in adult sensory neurons.

  Molecular and cellular neurosciences 20071001

• Interaction of the alternating double stranded copolymer poly(dA-dT) x poly(dA-dT) with NiCl(2) and CdCl(2): solution behavior.

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  Toxicology and applied pharmacology 20070515

• JNK1, but not JNK2, is required for COX-2 induction by nickel compounds.

  Carcinogenesis 20070401

• Effects of intrathecal injection of T-type calcium channel blockers in the rat formalin test.

  Behavioural pharmacology 20070201

• Dendritic calcium spikes induce bi-directional synaptic plasticity in the lateral amygdala.

  Neuropharmacology 20070101

• In vitro availability of ofloxacin in presence of metals essential to human body.

  Pakistan journal of pharmaceutical sciences 20070101

• Asymmetric fluorination of alpha-aryl acetic acid derivatives with the catalytic system NiCl2-Binap/R3SiOTf/2,6-lutidine.

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• EGFR-mediated expression of aquaporin-3 is involved in human skin fibroblast migration.

  The Biochemical journal 20061201

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• The Edinger-Westphal nucleus of the juvenile rat contains transient- and repetitive-firing neurons.

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  Environmental and molecular mutagenesis 20060401

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  Pakistan journal of pharmaceutical sciences 20060401

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  Pakistan journal of pharmaceutical sciences 20060401

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  Dalton transactions (Cambridge, England : 2003) 20060214

• The role of Ni(2+)-sensitive T-type Ca(2+) channels in the regulation of spontaneous excitation in detrusor smooth muscles of the guinea-pig bladder.

  BJU international 20060101

• SAMMA induces premature human acrosomal loss by Ca2+ signaling dysregulation.

  Journal of andrology 20060101

• Nickel(II) affects poly(ADP-ribose) polymerase-mediated DNA repair in normal and cancer cells.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20060101

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  Biomeditsinskaia khimiia 20060101

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  Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 20060101

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  Toxicology letters 20051215

• Use of the aquatic lichen Dermatocarpon luridum as bioindicator of copper pollution: accumulation and cellular distribution tests.

  Environmental pollution (Barking, Essex : 1987) 20051201

• Calcium concentration changes during sensory transduction in spider mechanoreceptor neurons.

  The European journal of neuroscience 20051201

• Essential role of PI-3K, ERKs and calcium signal pathways in nickel-induced VEGF expression.

  Molecular and cellular biochemistry 20051101

• Amperometric biosensing systems based on motility and gravitaxis of flagellate algae for aquatic risk assessment.

  Analytical chemistry 20051015

• Mechanisms of enhanced taurine release under Ca2+ depletion.

  Neurochemistry international 20051001

• TRPC4 knockdown suppresses epidermal growth factor-induced store-operated channel activation and growth in human corneal epithelial cells.

  The Journal of biological chemistry 20050916

• A Ni(2+)-sensitive component of the ERG b-wave from the isolated bovine retina is related to E-type voltage-gated Ca(2+) channels.

  Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20050901

• Gene expression profiling of hypoxia signaling in human hepatocellular carcinoma cells.

  Physiological genomics 20050811

• Direct effect of CoC12 and NiCl2 on citrate uptake by the rat renal brush border membrane.

  Industrial health 20050701

• Dendritic sodium spikelets and low-threshold calcium spikes in turtle olfactory bulb granule cells.

  Journal of neurophysiology 20050301

• Effects of three nickel salts on germinating seeds of Grevillea exul var. rubiginosa, an endemic serpentine Proteaceae.

  Annals of botany 20050301

• The role of voltage-gated Na+ channels in excitation-contraction coupling of rat heart determined by BmK I, an alpha-like scorpion neurotoxin.

  Toxicology in vitro : an international journal published in association with BIBRA 20050301

• Effect of divalent metal ions on DNA studied by capillary electrophoresis.

  Electrophoresis 20050301

• Redox imbalance induced by contact sensitizers triggers the maturation of dendritic cells.

  The Journal of investigative dermatology 20050301

• Cytokine transcript profiling in CD34+-progenitor derived dendritic cells exposed to contact allergens and irritants.

  Toxicology letters 20050115

• 5-Hydroxytryptamine action in the rat olfactory bulb: in vitro electrophysiological patch-clamp recordings of juxtaglomerular and mitral cells.

  Neuroscience 20050101

• Nodal/activin signaling establishes oral-aboral polarity in the early sea urchin embryo.

  Developmental dynamics : an official publication of the American Association of Anatomists 20041201

• Scavenging action of zinc and green tea polyphenol on cisplatin and nickel induced nitric oxide generation and lipid peroxidation in rats.

  Biomedical and environmental sciences : BES 20041201

• Effect of transition metal ions (cobalt and nickel chlorides) on intestinal iron absorption.

  European journal of clinical investigation 20040901

• Evidence that HSP70 gene expression may be useful for assessing the cytocompatibility of dental biomaterials.

  Dental materials journal 20040601

• Enhancement of excitatory postsynaptic potentials by preceding application of acetylcholine in mesencephalic dopamine neurons.

  Neuroscience research 20040501

• Capacitative calcium entry and TRPC channel proteins are expressed in rat distal pulmonary arterial smooth muscle.

  American journal of physiology. Lung cellular and molecular physiology 20040401

• Nodal and BMP2/4 signaling organizes the oral-aboral axis of the sea urchin embryo.

  Developmental cell 20040301

• Pigment cells trigger the onset of gastrulation in tropical sea urchin Echinometra mathaei.

  Development, growth & differentiation 20040201

• Nickel compounds act through phosphatidylinositol-3-kinase/Akt-dependent, p70(S6k)-independent pathway to induce hypoxia inducible factor transactivation and Cap43 expression in mouse epidermal Cl41 cells.

  Cancer research 20040101

• Inhibitors of hypoxic pulmonary vasoconstriction prevent high-altitude pulmonary edema in rats.

  Wilderness & environmental medicine 20040101

• Nickel impairs the repair of UV- and MNNG-damaged DNA.

  Cellular & molecular biology letters 20040101

• Properties of pacemaker potentials recorded from myenteric interstitial cells of Cajal distributed in the mouse small intestine.

  The Journal of physiology 20031215

• The sources and sequestration of Ca(2+) contributing to neuroeffector Ca(2+) transients in the mouse vas deferens.

  The Journal of physiology 20031201

• Nickel (Ni2+) enhancement of microtubule assembly in vitro is dependent on GTP function.

  Toxicology and applied pharmacology 20031201

• Fever-like temperature induces maturation of dendritic cells through induction of hsp90.

  International immunology 20030901

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  Sheng li xue bao : [Acta physiologica Sinica] 20030825

• Metal-1,4-dithio-2,3-dihydroxybutane chelates: novel inhibitors of the Rho transcription termination factor.

  Biochemistry 20030805

• Store-operated Ca2+ entry in first trimester and term human placenta.

  The Journal of physiology 20030715

• Cloning, expression, purification and crystallization of the N-domain from the alpha(2) subunit of the membrane-spanning Na,K-ATPase protein.

  Acta crystallographica. Section D, Biological crystallography 20030701

• The involvement of hypoxia-inducible transcription factor-1-dependent pathway in nickel carcinogenesis.

  Cancer research 20030701

• Inhibitors of Na+/H+ and Na+/Ca2+ exchange depress intracellular calcium elevation induced by ischemia/reperfusion in rat cardiac myocytes.

  Sheng li xue bao : [Acta physiologica Sinica] 20030625

• Nickel induces oxidative stress and genotoxicity in human lymphocytes.

  Toxicology and applied pharmacology 20030615

• The protein complex composed of nickel-binding SrnQ and DNA binding motif-bearing SrnR of Streptomyces griseus represses sodF transcription in the presence of nickel.

  The Journal of biological chemistry 20030516

• Effect of a chemical mixture on dermal penetration of arsenic and nickel in male pig in vitro.

  Journal of toxicology and environmental health. Part A 20030411

• Hydrodehalogenation of chlorobenzene on activated carbon and activated carbon supported catalysts.

  Chemosphere 20030301

• p38 Mitogen-activated protein kinase and extracellular signal-regulated kinases play distinct roles in the activation of dendritic cells by two representative haptens, NiCl2 and 2,4-dinitrochlorobenzene.

  The Journal of investigative dermatology 20030301

• Nickel-induced oxidative stress and effect of antioxidants in human lymphocytes.

  Archives of toxicology 20030301

• Nickel in subunit beta of the acetyl-CoA decarbonylase/synthase multienzyme complex in methanogens. Catalytic properties and evidence for a binuclear Ni-Ni site.

  The Journal of biological chemistry 20030221

• Role of the T-type Ca2+ current on the contractile performance of guinea pig detrusor smooth muscle.

  Neurourology and urodynamics 20030101

• Maintenance of sympathetic tone by a nickel chloride-sensitive mechanism in the rostral ventrolateral medulla of the adult rat.

  Neuroscience 20030101

• Optimisation of sample preparation methods for air imaging of ocular mucins by AFM.

  Ultramicroscopy 20030101

• Behavior and differentiation process of pigment cells in a tropical sea urchin Echinometra mathaei.

  Development, growth & differentiation 20030101

• Effects of salt and nickel ion on the conformational stability of Bacillus pasteurii UreE.

  FEBS letters 20020703

• Inflammatory responses and mucus secretion in rats with acute bronchiolitis induced by nickel chloride.

  Inhalation toxicology 20020401

• Free radicals-mediated induction of oxidized DNA bases and DNA-protein cross-links by nickel chloride.

  Mutation research 20020215

• Photoacoustic spectra of some biological metal chelates.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20020201

• Effect of soluble and particulate nickel compounds on the formation and repair of stable benzo[a]pyrene DNA adducts in human lung cells.

  Carcinogenesis 20020101

• [Effects of T-type calcium channel blockers on spontaneous meiotic maturation of mouse ovarian oocytes in vitro].

  Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20020101

• DNA damage in human colonic mucosa cells evoked by nickel and protective action of quercetin - involvement of free radicals?

  Cell biology and toxicology 20020101

• Osteoblast cell death on methacrylate polymers involves apoptosis.

  Journal of biomedical materials research 20011215

• Tolerance to nickel: oral nickel administration induces a high frequency of anergic T cells with persistent suppressor activity.

  Journal of immunology (Baltimore, Md. : 1950) 20011215

• Hydrogen peroxide mediates activation of nuclear factor of activated T cells (NFAT) by nickel subsulfide.

  Cancer research 20011115

• Differential effect of TEA on long-term synaptic modification in hippocampal CA1 and dentate gyrus in vitro.

  Neurobiology of learning and memory 20011101

• Maitotoxin-induced calcium entry in human lymphocytes: modulation by yessotoxin, Ca(2+) channel blockers and kinases.

  Cellular signalling 20011001

• Mechanism of trypsin-induced endothelium-dependent vasorelaxation in the porcine coronary artery.

  British journal of pharmacology 20011001

• Ca(2+) influx in the endothelial cells is required for the bradykinin-induced endothelium-dependent contraction in the porcine interlobar renal artery.

  The Journal of physiology 20010801

• Hard metal-induced disease: effects of metal cations in vitro on guinea pig isolated airways.

  Toxicology and applied pharmacology 20010801

• Spreading depression in human neocortical slices.

  Brain research 20010706

• Ni(2+), a double-acting inhibitor of neuronal nitric oxide synthase interfering with L-arginine binding and Ca(2+)/calmodulin-dependent enzyme activation.

  Biochemical and biophysical research communications 20010706

• Effects of nickel chloride on human platelets: enhancement of lipid peroxidation, inhibition of aggregation and interaction with ascorbic acid.

  Journal of toxicology and environmental health. Part A 20010323

• Involvement of the glycoproteic Ib-V-IX complex in nickel-induced platelet activation.

  Environmental health perspectives 20010301

• Conducted vasoconstriction in rat mesenteric arterioles: role for dihydropyridine-insensitive Ca(2+) channels.

  American journal of physiology. Heart and circulatory physiology 20010201

• DNA-protein crosslinks induced by nickel compounds in isolated rat lymphocytes: role of reactive oxygen species and specific amino acids.

  Toxicology and applied pharmacology 20010201

• alpha1H T-type Ca2+ channel is the predominant subtype expressed in bovine and rat zona glomerulosa.

  American journal of physiology. Cell physiology 20010201

• Age-dependent variation in contractility of adult cardiac myocytes.

  The international journal of biochemistry & cell biology 20010201

• Biochemical responses of Camellia sinensis (L.) O. Kuntze to heavy metal stress.

  Journal of environmental biology 20010101

• Modulation of phenotype, cytokine production and stimulatory function of CD34+-derived DC by NiCl(2) and SDS.

  Toxicology in vitro : an international journal published in association with BIBRA 20010101

• Compared effects of morphine and nickel chloride on NK cell activity in vitro in rats and monkeys.

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