695-53-4 | 5,5-Dimethyloxazolidine-2,4-dione

Packsize	Purity	Availability	Price	Discounted Price
1g	95%	in stock	$13.00	$9.00
5g	95%	in stock	$16.00	$11.00
10g	95%	in stock	$19.00	$14.00
25g	95%	in stock	$23.00	$17.00
100g	95%	in stock	$50.00	$35.00
500g	95%	in stock	$245.00	$171.00

Description

• Catalog Number: AC75216
• Chemical Name: 5,5-Dimethyloxazolidine-2,4-dione
• CAS Number: 695-53-4
• Molecular Formula: C5H7NO3
• Molecular Weight: 129.114
• MDL Number: MFCD00005379
• SMILES: O=C1NC(=O)C(O1)(C)C

Computed Properties

• Complexity: 173
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 9
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 1
• XLogP3: 0.1

Literature

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  Toxicology 20141204

• In utero dimethadione exposure causes postnatal disruption in cardiac structure and function in the rat.

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  Journal of medicinal chemistry 20111222

• Co-variation in frequency and severity of cardiovascular and skeletal defects in Sprague-Dawley rats after maternal administration of dimethadione, the N-demethylated metabolite of trimethadione.

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  Bioorganic & medicinal chemistry letters 20101101

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  Reproductive biomedicine online 20100801

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• The clinical importance of the trimethadione tolerance test as a method for quantitative assessment of hepatic functional reserve in patients with biliary atresia.

  Journal of clinical pharmacy and therapeutics 20011201

• Na(+)-dependent pH regulation by the amitochondriate protozoan parasite Giardia intestinalis.

  The Journal of biological chemistry 20010803

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  Biology of reproduction 20010601

• Trimethadione N-demethylation by rat liver CYP2E1 in vitro.

  Research communications in molecular pathology and pharmacology 19960701

• Effects of the oxazolidinedione anticonvulsants trimethadione and dimethadione and the barbiturate homolog 5,5-dimethylbarbituric acid on N-nitrosodiethylamine-initiated renal and hepatic carcinogenesis in the F344/NCr rat.

  Archives of toxicology 19920101

• Characterization of ethosuximide reduction of low-threshold calcium current in thalamic neurons.

  Annals of neurology 19890601

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  Neuroscience letters 19890313

• Cardiac defects in children of mothers receiving anticonvulsant therapy during pregnancy.

  The Journal of pediatrics 19760801