6960-45-8 | 7-Nitroindole-2-carboxylic acid

Packsize	Purity	Availability	Price	Discounted Price
1mg	97%	in stock	$6.00	$4.00
25mg	97%	in stock	$7.00	$5.00
50mg	97%	in stock	$9.00	$6.00
250mg	97%	in stock	$28.00	$19.00
1g	95%	in stock	$48.00	$34.00
5g	97%	in stock	$75.00	$52.00

Description

• Catalog Number: AB70180
• Chemical Name: 7-Nitroindole-2-carboxylic acid
• CAS Number: 6960-45-8
• Molecular Formula: C9H6N2O4
• Molecular Weight: 206.1549
• MDL Number: MFCD00044720
• SMILES: [O-][N+](=O)c1cccc2c1[nH]c(c2)C(=O)O
• NSC Number: 69877

Computed Properties

• Complexity: 288
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 15
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 1
• XLogP3: 1.7

Literature

• Synthesis, biological evaluation, and structure-activity relationships of a novel class of apurinic/apyrimidinic endonuclease 1 inhibitors.

  Journal of medicinal chemistry 20120412

• Lucanthone and its derivative hycanthone inhibit apurinic endonuclease-1 (APE1) by direct protein binding.

  PloS one 20110101

• Genome-wide reprogramming in the mouse germ line entails the base excision repair pathway.

  Science (New York, N.Y.) 20100702

• Cross-talk-free dual-color fluorescence cross-correlation spectroscopy for the study of enzyme activity.

  Analytical chemistry 20100215

• Radiation resistance in glioma cells determined by DNA damage repair activity of Ape1/Ref-1.

  Journal of radiation research 20100101

• Identification and characterization of inhibitors of human apurinic/apyrimidinic endonuclease APE1.

  PloS one 20090101