70254-61-4 | 2-Hydroxy-6-methyl-4h-pyran-4-one

Packsize	Purity	Availability	Price	Discounted Price
250mg	95%	in stock	$363.00	$254.00
1g	95%	in stock	$853.00	$597.00

Description

• Catalog Number: AC75452
• Chemical Name: 2-Hydroxy-6-methyl-4h-pyran-4-one
• CAS Number: 70254-61-4
• Molecular Formula: C6H6O3
• Molecular Weight: 126.11
• MDL Number: MFCD18820248
• SMILES: Cc1oc(O)cc(=O)c1
• NSC Number: 34625

Computed Properties

• Complexity: 200
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 9
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 1
• XLogP3: 0.5

Literature

• Structure-anti-leukemic activity relationship study of ortho-dihydroxycoumarins in U-937 cells: key role of the δ-lactone ring in determining differentiation-inducing potency and selective pro-apoptotic action.

  Bioorganic & medicinal chemistry 20120915

• Synthesis and antimicrobial evaluation of new pyrano[4,3-b]pyran and Pyrano[3,2-c]chromene derivatives bearing a 2-thiophenoxyquinoline nucleus.

  Archiv der Pharmazie 20120401

• Ethyl 2-(2-amino-5-methyl-1,2,4-triazolo[1,5-a]pyrimidin-7-yl)acetate.

  Acta crystallographica. Section E, Structure reports online 20120101

• Single step synthesis of strigolactone analogues from cyclic keto enols, germination stimulants for seeds of parasitic weeds.

  Bioorganic & medicinal chemistry 20110815

• 4-Hy-droxy-3-[(4-hy-droxy-6-methyl-2-oxo-3,6-dihydro-2H-pyran-3-yl)(3-thien-yl)meth-yl]-6-methyl-3,6-dihydro-2H-pyran-2-one.

  Acta crystallographica. Section E, Structure reports online 20110201

• Polyketide derivatives active against Botrytis cinerea in Gerbera hybrida.

  Planta 20110101

• 3,4,6-Trimethyl-1-phenyl-1H-pyrazolo-[3,4-b]pyridine.

  Acta crystallographica. Section E, Structure reports online 20100801

• Synthesis and in-vitro cytotoxic evaluation of novel pyridazin-4-one derivatives.

  Archiv der Pharmazie 20100501

• Diastereoselective synthesis of polycyclic acetal-fused pyrano[3,2-c]pyran-5(2H)-one derivatives.

  The Journal of organic chemistry 20090306

• Tricyclic pyrone compounds prevent aggregation and reverse cellular phenotypes caused by expression of mutant huntingtin protein in striatal neurons.

  BMC neuroscience 20090101

• Crystallization and preliminary X-ray diffraction studies of polyketide synthase-1 (PKS-1) from Cannabis sativa.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20080301

• Microbial synthesis of triacetic acid lactone.

  Biotechnology and bioengineering 20060305

• A unique highly oxygenated pyrano[4,3-c][2]benzopyran-1,6-dione derivative with antioxidant and cytotoxic activities from the fungus Phellinus igniarius.

  Organic letters 20050428

• Convenient replacement of the hydroxy by an amino group in 4 hydroxycoumarin and 4-hydroxy-6-methyl-2-pyrone under microwave irradiation.

  Molecules (Basel, Switzerland) 20040731

• Rational pathway engineering of type I fatty acid synthase allows the biosynthesis of triacetic acid lactone from D-glucose in vivo.

  Journal of the American Chemical Society 20040414

• Direct asymmetric Michael reactions of cyclic 1,3-dicarbonyl compounds and enamines catalyzed by chiral bisoxazoline-copper(II) complexes.

  The Journal of organic chemistry 20030627

• Gas chromatography/mass spectrometric characterisation of pyrolysis/silylation products of glucose and cellulose.

  Rapid communications in mass spectrometry : RCM 20020101

• Syntheses and biological activities of pyranyl-substituted cinnamates.

  Bioscience, biotechnology, and biochemistry 20010101