7144-05-0 | piperidin-4-ylmethanamine

Packsize	Purity	Availability	Price	Discounted Price
1g	96%	in stock	$7.00	$5.00
5g	96%	in stock	$19.00	$14.00
25g	95%	in stock	$82.00	$58.00
100g	95%	in stock	$299.00	$209.00
500g	>98.0%(GC)(T)	in stock	$1,063.00	$744.00

Description

• Catalog Number: AB65898
• Chemical Name: piperidin-4-ylmethanamine
• CAS Number: 7144-05-0
• Molecular Formula: C6H14N2
• Molecular Weight: 114.1888
• MDL Number: MFCD00006007
• SMILES: NCC1CCNCC1
• NSC Number: 62826

Computed Properties

• Complexity: 57.5
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 8
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 1
• XLogP3: -0.4

Literature

• Structure-guided evolution of potent and selective CHK1 inhibitors through scaffold morphing.

  Journal of medicinal chemistry 20111222

• Discovery of 4-amino-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamides as selective, orally active inhibitors of protein kinase B (Akt).

  Journal of medicinal chemistry 20100311

• Design, synthesis, characterization, and biological evaluation of triazine dendrimers bearing paclitaxel using ester and ester/disulfide linkages.

  Bioconjugate chemistry 20091101

• Identification of 4-(4-aminopiperidin-1-yl)-7H-pyrrolo[2,3-d]pyrimidines as selective inhibitors of protein kinase B through fragment elaboration.

  Journal of medicinal chemistry 20080410

• Identification of a novel 4-aminomethylpiperidine class of M3 muscarinic receptor antagonists and structural insight into their M3 selectivity.

  Journal of medicinal chemistry 20060921

• Novel substituted 4-aminomethylpiperidines as potent and selective human beta3-agonists. Part 1: aryloxypropanolaminomethylpiperidines.

  Bioorganic & medicinal chemistry letters 20021021

• Novel substituted 4-aminomethylpiperidines as potent and selective human beta3-agonists. Part 2: arylethanolaminomethylpiperidines.

  Bioorganic & medicinal chemistry letters 20021021