71989-14-5 | Fmoc-Asp(OtBu)-OH

Packsize	Purity	Availability	Price	Discounted Price
250mg	98%	in stock	$6.00	$4.00
5g	95%	in stock	$7.00	$5.00
10g	98%	in stock	$12.00	$8.00
25g	>98%	in stock	$23.00	$16.00
100g	95%	in stock	$55.00	$39.00

Description

• Catalog Number: AB46167
• Chemical Name: Fmoc-Asp(OtBu)-OH
• CAS Number: 71989-14-5
• Molecular Formula: C23H25NO6
• Molecular Weight: 411.4477
• MDL Number: MFCD00037131
• SMILES: O=C(N[C@H](C(=O)O)CC(=O)OC(C)(C)C)OCC1c2ccccc2c2c1cccc2

Computed Properties

• Complexity: 620
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 30
• Hydrogen Bond Acceptor Count: 6
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 9
• XLogP3: 3.5

Upstream Synthesis Route

Fmoc-L-Asp(OtBu)-OH is a key reagent in chemical synthesis processes, particularly in the field of peptide synthesis. This amino acid derivative is widely utilized for its ability to introduce a protected aspartic acid residue into the growing peptide chain. By incorporating Fmoc-L-Asp(OtBu)-OH at specific points during the synthesis, chemists can control the sequence and structure of the peptide being produced.In solid-phase peptide synthesis, Fmoc-L-Asp(OtBu)-OH is commonly used as a building block to construct complex peptides with specific functionality. The Fmoc (fluorenylmethyloxycarbonyl) group serves as a temporary protecting group, facilitating the stepwise assembly of the peptide chain on a solid support. The OtBu (tert-butyloxycarbonyl) group on the aspartic acid side chain provides additional protection, preventing undesired side reactions and ensuring the fidelity of the synthesis process.Overall, the application of Fmoc-L-Asp(OtBu)-OH enables chemists to efficiently and selectively incorporate aspartic acid residues into peptides, offering precise control over peptide design and functionality. Its versatility and reliability make it a valuable tool in peptide chemistry and drug development research.