7206-70-4 | 4-Amino-5-chloro-2-methoxybenzoic acid

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$15.00	$10.00
5g	98%	in stock	$28.00	$19.00
25g	98%	in stock	$66.00	$47.00
100g	98%	in stock	$175.00	$123.00
500g	98%	in stock	$757.00	$530.00

Description

• Catalog Number: AB66624
• Chemical Name: 4-Amino-5-chloro-2-methoxybenzoic acid
• CAS Number: 7206-70-4
• Molecular Formula: C8H8ClNO3
• Molecular Weight: 201.60702000000003
• MDL Number: MFCD00038794
• SMILES: COc1cc(N)c(cc1C(=O)O)Cl

Computed Properties

• Complexity: 200
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 13
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 2
• XLogP3: 2.1

Literature

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• Antidepressant-like effects of neferine in the forced swimming test involve the serotonin1A (5-HT1A) receptor in mice.

  European journal of pharmacology 20100525

• Involvement of the 5-HT(1A) receptor in the anti-immobility effects of fluvoxamine in the forced swimming test and mouse strain differences in 5-HT(1A) receptor binding.

  European journal of pharmacology 20100310

• Synthesis and structure-activity relationships of 4-amino-5-chloro-N-(1,4-dialkylhexahydro-1,4-diazepin-6-yl)-2-methoxybenzamide derivatives, novel and potent serotonin 5-HT3 and dopamine D2 receptors dual antagonist.

  Chemical & pharmaceutical bulletin 20020701

• Endogenous 5-HT tonically inhibits spontaneous firing activity of dorsal hippocampus CA1 pyramidal neurons through stimulation of 5-HT(1A) receptors in quiet awake rats: in vivo electrophysiological evidence.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20010201