7209-38-3 | 1,4-Bis(3-aminopropyl)piperazine

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$26.00	$18.00
5g	98%	in stock	$34.00	$24.00
25g	98%	in stock	$74.00	$52.00
100g	98%	in stock	$203.00	$142.00
500g	98%	in stock	$573.00	$402.00

Description

• Catalog Number: AB42654
• Chemical Name: 1,4-Bis(3-aminopropyl)piperazine
• CAS Number: 7209-38-3
• Molecular Formula: C10H24N4
• Molecular Weight: 200.3244
• MDL Number: MFCD00006161
• SMILES: NCCCN1CCN(CC1)CCCN

Computed Properties

• Complexity: 116
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 14
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 6
• XLogP3: -1.4

Literature

• Retraction notice to 'Layer silicates modified with 1,4-bis(3-aminopropyl)piperazine for the removal of Th(IV), U(VI) and Eu(III) from aqueous media' [J. Hazard. Mater. 171 (2009) 514-523].

  Journal of hazardous materials 20111030

• New ferrocenic pyrrolo[1,2-a]quinoxaline derivatives: synthesis, and in vitro antimalarial activity--Part II.

  European journal of medicinal chemistry 20110601

• Synthesis and in vitro biological evaluation of new polyamine conjugates as potential anticancer drugs.

  European journal of medicinal chemistry 20101201

• Synthesis and cytotoxic activity of a new potential DNA bisintercalator: 1,4-Bis{3-[N-(4-chlorobenzo[g]phthalazin-1-yl)aminopropyl]}piperazine.

  Bioorganic & medicinal chemistry 20100715

• Layer silicates modified with 1,4-bis(3-aminopropyl)piperazine for the removal of Th(IV), U(VI) and Eu(III) from aqueous media.

  Journal of hazardous materials 20091115

• Designed pendant chain covalently bonded to analogue of heulandite for removal of divalent toxic metals from aqueous solution: thermodynamic and equilibrium study.

  Journal of colloid and interface science 20090901

• Synthesis, characterization, and properties of organically templated lanthanide oxalatophosphates with a three-dimensional honeycomb structure: (H4APPIP)[Ln3(C2O4)(5.5)(H2PO4)2].5H2O (Ln = Er-Lu, APPIP = 1,4-bis(3-aminopropyl)piperazine).

  Inorganic chemistry 20090216

• New ferrocenic pyrrolo[1,2-a]quinoxaline derivatives: synthesis, and in vitro antimalarial activity.

  Bioorganic & medicinal chemistry 20081015

• Synthesis and preliminary evaluation of new ursolic and oleanolic acids derivatives as antileishmanial agents.

  Journal of enzyme inhibition and medicinal chemistry 20081001

• Designed pendant chain covalently bonded to silica gel for cation removal.

  Journal of hazardous materials 20080815

• Synthesis, structure, and polymorphism studies in amine-templated open-framework zinc phosphites.

  Inorganic chemistry 20080616

• Pharmacomodulation on the 3-acetylursolic acid skeleton: Design, synthesis, and biological evaluation of novel N-{3-[4-(3-aminopropyl)piperazinyl]propyl}-3-O-acetylursolamide derivatives as antimalarial agents.

  Bioorganic & medicinal chemistry 20080115

• Development of piperazine-tethered heterodimers as potent antimalarials against chloroquine-resistant P. falciparum strains. Synthesis and molecular modeling.

  Bioorganic & medicinal chemistry letters 20070701

• One pot synthesis of pyrimidine and bispyrimidine derivatives and their evaluation for anti-inflammatory and analgesic activities.

  Bioorganic & medicinal chemistry 20070515

• [Thieno[3,2-c]quinoline-4-yl-amines--synthesis and investigation of activity against malaria].

  Die Pharmazie 20060401

• 1,4-bis(3-aminopropyl)piperazine libraries: from the discovery of classical chloroquine-like antimalarials to the identification of new targets.

  Combinatorial chemistry & high throughput screening 20050201

• Synthesis, antimalarial activity, and molecular modeling of new pyrrolo[1,2-a]quinoxalines, bispyrrolo[1,2-a]quinoxalines, bispyrido[3,2-e]pyrrolo[1,2-a]pyrazines, and bispyrrolo[1,2-a]thieno[3,2-e]pyrazines.

  Journal of medicinal chemistry 20040408

• Synthesis and antimalarial evaluation of new 1,4-bis(3-aminopropyl)piperazine derivatives.

  Bioorganic & medicinal chemistry letters 20031103

• Recent news related to substrates and inhibitors of plant amine oxidases.

  Biochimica et biophysica acta 20030411

• Synthesis and in vitro and in vivo antimalarial activity of N1-(7-chloro-4-quinolyl)-1,4-bis(3-aminopropyl)piperazine derivatives.

  Journal of medicinal chemistry 20030213