7212-44-4 | (6E)-3,7,11-trimethyldodeca-1,6,10-trien-3-ol

Packsize	Purity	Availability	Price	Discounted Price
5g	95%	in stock	$8.00	$5.00
25g	95%	in stock	$34.00	$24.00
100g	95%	in stock	$79.00	$55.00

Description

• Catalog Number: AC92982
• Chemical Name: (6E)-3,7,11-trimethyldodeca-1,6,10-trien-3-ol
• CAS Number: 7212-44-4
• Molecular Formula: C15H26O
• Molecular Weight: 222.36634000000004
• MDL Number: MFCD00008911
• SMILES: C=CC(CCC=C(CCC=C(C)C)C)(O)C

Computed Properties

• Complexity: 269
• Covalently-Bonded Unit Count: 1
• Defined Bond Stereocenter Count: 1
• Heavy Atom Count: 16
• Hydrogen Bond Acceptor Count: 1
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 7
• Undefined Atom Stereocenter Count: 1
• XLogP3: 4.6

Literature

• Hedycaryol synthase in complex with nerolidol reveals terpene cyclase mechanism.

  Chembiochem : a European journal of chemical biology 20140124

• Activity of tea tree oil and nerolidol alone or in combination against Pediculus capitis (head lice) and its eggs.

  Parasitology research 20121101

• Volatiles from apple trees infested with light brown apple moth larvae attract the parasitoid Dolichogenidia tasmanica.

  Journal of agricultural and food chemistry 20120926

• Biosynthesis of wine aroma: transcript profiles of hydroxymethylbutenyl diphosphate reductase, geranyl diphosphate synthase, and linalool/nerolidol synthase parallel monoterpenol glycoside accumulation in Gewürztraminer grapes.

  Planta 20120901

• Transdermal behaviors comparisons among Evodia rutaecarpa extracts with different purity of evodiamine and rutaecarpine and the effect of topical formulation in vivo.

  Fitoterapia 20120701

• Chemical diversity of essential oils from Asteriscus graveolens (Forssk.) less.: identification of cis-8-Acetoxychrysanthenyl acetate as a new natural component.

  Chemistry & biodiversity 20120401

• Nerolidol effects on mitochondrial and cellular energetics.

  Toxicology in vitro : an international journal published in association with BIBRA 20120301

• Identification, functional characterization, and regulation of the enzyme responsible for floral (E)-nerolidol biosynthesis in kiwifruit (Actinidia chinensis).

  Journal of experimental botany 20120301

• Identification and characterization of the linalool/nerolidol synthase from Streptomyces clavuligerus.

  Chembiochem : a European journal of chemical biology 20111104

• [Analyze on chemical compositions of Dalbergia odorifera essential oils extracted by CO2-supercritical-fluid-extraction and steam distillation extraction].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20111101

• In vivo genotoxicity assessment of nerolidol.

  Journal of applied toxicology : JAT 20111001

• Toxicity of Rhododendron anthopogonoides essential oil and its constituent compounds towards Sitophilus zeamais.

  Molecules (Basel, Switzerland) 20110825

• Evaluation of the mutagenicity of sesquiterpenic compounds and their influence on the susceptibility towards antibiotics of two clinically relevant bacterial strains.

  Mutation research 20110714

• Conversion of airborne nerolidol to DMNT emission requires additional signals in Achyranthes bidentata.

  FEBS letters 20110623

• In vitro and in vivo activity of three sesquiterpenes against L(3) larvae of Anisakis type I.

  Experimental parasitology 20110201

• Chemical composition of essential oils from leaves, stems, flower heads and roots of Conyza bonariensis L. from Tunisia.

  Natural product research 20110101

• Effects of immunotoxic activity of the major essential oil of Angelica purpuraefolia Chung against Aedes aegypti L.

  Immunopharmacology and immunotoxicology 20101201

• The effect of terpenes on percutaneous absorption of tiaprofenic acid gel.

  Archives of pharmacal research 20101101

• The molecular basis of host plant selection in Melaleuca quinquenervia by a successful biological control agent.

  Phytochemistry 20100801

• Inhibitory effect of terpene nerolidol on the growth of Babesia parasites.

  Parasitology international 20100601

• Sesquiterpenes from Oplopanax horridus.

  Journal of natural products 20100423

• Addendum to Fragrance material review on Nerolidol (isomer unspecified).

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100101

• Different approaches for improving skin accumulation of topical corticosteroids.

  International journal of pharmaceutics 20091001

• Effect of citral, eugenol, nerolidol and alpha-terpineol on the ultrastructural changes of Trichophyton mentagrophytes.

  Fitoterapia 20090701

• [Simultaneous determination of water-soluble components and nerolidol in xiangdan injection by high performance liquid chromatography with column switching].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20081201

• Fragrance material review on cis-nerolidol.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20081101

• Fragrance material review on nerolidol (isomer unspecified).

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20081101

• Two nearly identical terpene synthases catalyze the formation of nerolidol and linalool in snapdragon flowers.

  The Plant journal : for cell and molecular biology 20080701

• Biosynthesis of the earthy odorant geosmin by a bifunctional Streptomyces coelicolor enzyme.

  Nature chemical biology 20071101

• Composition and cytotoxic activity of the leaf essential oil of Comptonia peregrina (L.) Coulter.

  Phytotherapy research : PTR 20070601

• The effect of terpene concentrations on the skin penetration of diclofenac sodium.

  International journal of pharmaceutics 20070420

• Antifungal effect of eugenol and nerolidol against Microsporum gypseum in a guinea pig model.

  Biological & pharmaceutical bulletin 20070101

• Nerolidol, an antiulcer constituent from the essential oil of Baccharis dracunculifolia DC (Asteraceae).

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20070101

• Biosynthesis of mono- and sesquiterpenes in strawberry fruits and foliage: 2H labeling studies.

  Journal of agricultural and food chemistry 20060222

• Identification, molecular cloning and functional characterization of an octaprenyl pyrophosphate synthase in intra-erythrocytic stages of Plasmodium falciparum.

  The Biochemical journal 20051115

• Plant science. New gene boosts plant's defenses against pests.

  Science (New York, N.Y.) 20050923

• Genetic engineering of terpenoid metabolism attracts bodyguards to Arabidopsis.

  Science (New York, N.Y.) 20050923

• Bioavailability of nerodilol-based transdermal therapeutic system of nicorandil in human volunteers.

  Journal of controlled release : official journal of the Controlled Release Society 20050818

• [Determination of nerolidol in volatile oil of Dalbergia odorifera by GC].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050601

• Biomimetic synthesis of acid-sensitive (-)-caparrapi oxide and (+)-8-epicaparrapi oxide induced by artificial cyclases.

  Organic letters 20050414

• Vanadium bromoperoxidase-catalyzed biosynthesis of halogenated marine natural products.

  Journal of the American Chemical Society 20041124

• Gain and loss of fruit flavor compounds produced by wild and cultivated strawberry species.

  The Plant cell 20041101

• The antibacterial effects of terpene alcohols on Staphylococcus aureus and their mode of action.

  FEMS microbiology letters 20040815

• Differential timing of spider mite-induced direct and indirect defenses in tomato plants.

  Plant physiology 20040501

• Characterization of nerolidol biotransformation based on indirect on-line estimation of biomass concentration and physiological state in batch cultures of Aspergillus niger.

  Biotechnology progress 20040101

• Content and composition of the essential oil of Thymus serpyllum L. growing wild in Estonia.

  Medicina (Kaunas, Lithuania) 20040101

• Terpenoid metabolism in wild-type and transgenic Arabidopsis plants.

  The Plant cell 20031201

• Activity and mechanisms of action of selected biocidal agents on Gram-positive and -negative bacteria.

  Journal of applied microbiology 20030101

• The maize gene terpene synthase 1 encodes a sesquiterpene synthase catalyzing the formation of (E)-beta-farnesene, (E)-nerolidol, and (E,E)-farnesol after herbivore damage.

  Plant physiology 20021201

• African elephant sesquiterpenes. II. Identification and synthesis of new derivatives of 2,3-dihydrofarnesol.

  Journal of natural products 20020901

• [Study on the chemical constituents of the volatile oil from Lysimachia trientaloides Hemsl].

  Se pu = Chinese journal of chromatography 20020501

• Characterization of the isoprenoid chain of coenzyme Q in Plasmodium falciparum.

  FEMS microbiology letters 20020122

• (+)-epi-Alpha-bisabolol [correction of bisbolol] is the wound-healing principle of Peperomia galioides: investigation of the in vivo wound-healing activity of related terpenoids.

  Journal of natural products 20011001

• Spider mite-induced (3S)-(E)-nerolidol synthase activity in cucumber and lima bean. The first dedicated step in acyclic C11-homoterpene biosynthesis.

  Plant physiology 19990901